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GYPENOSIDE
September 24, 2022
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EXTRACELLULAR MICROVESICLES
September 24, 2022
  1. Metabolic messengers: FGF21
  2. Advances in biological functions and clinical studies of FGF21
  3. FGF21 in obesity and cancer: New insights
  4. A pyrexic effect of FGF21 independent of energy expenditure and UCP1
  5. FGF21 promotes thermogenic gene expression as an autocrine factor in adipocytes
  6. FGF21 suppresses alcohol consumption through an amygdalo-striatal circuit
  7. Stress-induced FGF21 and GDF15 in obesity and obesity resistance
  8. FGF19 and FGF21: In NASH we trust
  9. The roles and pharmacological effects of FGF21 in preventing aging-associated metabolic diseases
  10. Hepatic hormone FGF21 and its analogues in clinical trials
  11. Gut microbiota mediate the FGF21 adaptive stress response to chronic dietary protein-restriction in mice
  12. Association between serum FGF21 level and sarcopenia in older adults
  13. FGF21 facilitates autophagy in prostate cancer cells by inhibiting the PI3K–Akt–mTOR signaling pathway
  14. Neuroprotective effects of the FGF21 analogue LY2405319
  15. Hepatic FGF21 preserves thermoregulation and cardiovascular function during bacterial inflammation
  16. A feed-forward regulatory loop in adipose tissue promotes signaling by the hepatokine FGF21
  17. FGF21 is required for protein restriction to extend lifespan and improve metabolic health in male mice
  18. Pharmacological treatment with FGF21 strongly improves plasma cholesterol metabolism to reduce atherosclerosis
  19. Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21
  20. The Nuanced Metabolic Functions of Endogenous FGF21 Depend on the Nature of the Stimulus, Tissue Source, and Experimental Model
  21. OPA1 deletion in brown adipose tissue improves thermoregulation and systemic metabolism via FGF21
  22. Diagnostic value of serum biomarkers FGF21 and GDF15 compared to muscle sample in mitochondrial disease
  23. Hepatic P38 activation modulates systemic metabolism through FGF21-mediated interorgan communication
  24. FGF21 promotes non-small cell lung cancer progression by SIRT1/PI3K/AKT signaling
  25. Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and-independent mechanisms
  26. Central FGF21 production regulates memory but not peripheral metabolism
  27. Differential roles of GDF15 and FGF21 in systemic metabolic adaptation to the mitochondrial integrated stress response
  28. FGF21 prevents low-protein diet-induced renal inflammation in aged mice
  29. The same metabolic response to FGF21 administration in male and female obese mice is accompanied by sex-specific changes in adipose tissue gene expression
  30. Higher fasting plasma FGF21 concentration is associated with lower ad libitum soda consumption in humans
  31. Disease-specific plasma levels of mitokines FGF21, GDF15, and Humanin in type II diabetes and Alzheimer’s disease in comparison with healthy aging
  32. FGF21 is required for the metabolic benefits of IKKε/TBK1 inhibition
  33. Hepatic CPT1A Facilitates Liver–Adipose Cross Talk via Induction of FGF21 in Mice
  34. LLF580, an FGF21 analog, reduces triglycerides and hepatic fat in obese adults with modest hypertriglyceridemia
  35. FGF21 (Fibroblast Growth Factor 21) defines a potential cardiohepatic signaling circuit in end-stage heart failure
  36. FGF21 serum levels are related to insulin resistance, metabolic changes and obesity in Mexican people living with HIV (PLWH)
  37. FGF21 promotes migration and differentiation of epidermal cells during wound healing via SIRT1‐dependent autophagy
  38. Relationship between FGF21 and drug or nondrug therapy of type 2 diabetes mellitus
  39. Integration of FGF21 signaling and metabolomics in high-fat diet-induced obesity
  40. FGF21 induced by the ASK1-p38 pathway promotes mechanical cell competition by attracting cells
  41. FGF21/adiponectin ratio predicts deterioration in glycemia: a 4.6-year prospective study in China
  42. FGF21 ameliorates hepatic fibrosis by multiple mechanisms
  43. Ultrasound-assisted C3F8-filled PLGA nanobubbles for enhanced FGF21 delivery and improved prophylactic treatment of diabetic cardiomyopathy
  44. Anterograde regulation of mitochondrial genes and FGF21 signaling by hepatic LSD1
  45. Deadenylase-dependent mRNA decay of GDF15 and FGF21 orchestrates food intake and energy expenditure
  46. Dynamic folding modulation generates FGF21 variant against diabetes
  47. Serum FGF21 levels are altered by various factors including lifestyle behaviors in male subjects
  48. FoxO1 suppresses FGF21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance
  49. FGF21 modulates mitochondrial stress response in cardiomyocytes only under mild mitochondrial dysfunction
  50. Association of plasma FGF21 levels with muscle mass and muscle strength in a national multicentre cohort study: Korean Frailty and Aging Cohort Study
  51. Bupleuri radix extract ameliorates impaired lipid metabolism in high-fat diet-induced obese mice via gut microbia-mediated regulation of FGF21 signaling …
  52. FGF21: A novel regulator of glucose and lipid metabolism and whole-body energy balance
  53. Pubertal FGF21 deficit is central in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome
  54. Severe protein deficiency induces hepatic expression and systemic level of FGF21 but inhibits its hypothalamic expression in growing rats
  55. Short‐term protein restriction at advanced age stimulates FGF21 signalling, energy expenditure and browning of white adipose tissue
  56. Sulforaphane Regulates Glucose and Lipid Metabolisms in Obese Mice by Restraining JNK and Activating Insulin and FGF21 Signal Pathways
  57. Phytochemicals from the cocoa shell modulate mitochondrial function, lipid and glucose metabolism in hepatocytes via activation of FGF21/ERK, AKT, and mTOR …
  58. Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway
  59. Serum levels of FGF21, β-klotho, and BDNF in stable coronary artery disease patients with depressive symptoms: a cross-sectional single-center study
  60. Retinal glial remodeling by FGF21 preserves retinal function during photoreceptor degeneration
  61. Dietary Patterns and Their Associations With the FTO and FGF21 Gene Variants Among Emirati Adults
  62. Alginate self-adhesive hydrogel combined with dental pulp stem cells and FGF21 repairs hemisection spinal cord injury via apoptosis and autophagy …
  63. Mice with high FGF21 serum levels had a reduced preference for morphine and an attenuated development of acute antinociceptive tolerance and physical …
  64. Leptin, Acting at Central Level, Increases FGF21 Expression in White Adipose Tissue via PPARβ/δ
  65. FGF21 promotes ischaemic angiogenesis and endothelial progenitor cells function under diabetic conditions in an AMPK/NAD+‐dependent manner
  66. Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart
  67. FOXO1 inhibition synergizes with FGF21 to normalize glucose control in diabetic mice
  68. Preparation, characterization, and pharmacological study of a novel long-acting FGF21 with a potential therapeutic effect in obesity
  69. Ahnak deficiency attenuates high-fat diet-induced fatty liver in mice through FGF21 induction
  70. Plasma from healthy donors protects blood–brain barrier integrity via FGF21 and improves the recovery in a mouse model of cerebral ischaemia
  71. FGF21 attenuates high uric acid‑induced endoplasmic reticulum stress, inflammation and vascular endothelial cell dysfunction by activating Sirt1
  72. P7C3‐A20 alleviates fatty liver by shaping gut microbiota and inducing FGF21/FGF1, via the AMP‐activated protein kinase/CREB regulated transcription coactivator 2 …
  73. The miR-182-5p/FGF21/acetylcholine axis mediates the crosstalk between adipocytes and macrophages to promote beige fat thermogenesis
  74. Levels of β-klotho determine the thermogenic responsiveness of adipose tissues: Involvement of the autocrine action of FGF21
  75. Neural afferents as potential targets to ameliorate FGF21-mediated sympathoexcitation
  76. The role of FGF21 in the pathogenesis of cardiovascular disease
  77. Fibroblast growth factor 21 (FGF21) alleviates senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the SIRT1-mTOR signaling …
  78. Pharmacological FGF21 signals to glutamatergic neurons to enhance leptin action and lower body weight during obesity
  79. Long-term adjustment of hepatic lipid metabolism after chronic stress and the role of FGF21
  80. MiR-26b-5p regulates the preadipocyte differentiation by targeting FGF21 in goats
  81. Does FGF21 Mediate the Potential Decrease in Sweet Food Intake and Preference Following Bariatric Surgery?
  82. FGF21 enhances therapeutic efficacy and reduces side effects of dexamethasone in treatment of rheumatoid arthritis
  83. FGF21 Serum Levels in the Early Second Trimester Are Positively Correlated With the Risk of Subsequent Gestational Diabetes Mellitus: A Propensity …
  84. Behavioral, Hormonal, Inflammatory, and Metabolic Effects Associated with FGF21-Pathway Activation in an ALS Mouse Model
  85. FGF21: a promising therapeutic agent for alcoholic cardiomyopathy?†
  86. Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with …
  87. The relationship between sarcopenia detected in newly diagnosed colorectal cancer patients and FGF21, irisin and CRP levels
  88. FGF21 attenuates hypoxia‑induced dysfunction and inflammation in HPAECs via the microRNA‑27b‑mediated PPARγ pathway
  89. Pegbelfermin, a PEGylated FGF21 analogue, has pharmacology without bone toxicity after 1-year dosing in skeletally-mature monkeys
  90. FGF21 controls hepatic lipid metabolism via sex-dependent interorgan crosstalk
  91. Suppressive Effect of Autocrine FGF21 on Autophagy-Deficient Hepatic Tumorigenesis
  92. Novel adipokines CTRP1, CTRP9, and FGF21 in pediatric type 1 and type 2 diabetes: a cross-sectional analysis
  93. A novel GLP-1 and FGF21 dual agonist has therapeutic potential for diabetes and non-alcoholic steatohepatitis
  94. FGF21 impedes peripheral myelin development by stimulating p38 MAPK/c‐Jun axis
  95. Bicistronic reporter mice for monitoring of FGF21 expression
  96. Nutritional Regulation of Hepatic FGF21 by Dietary Restriction of Methionine
  97. FGF21 response to sucrose is associated with BMI and dorsal striatal signaling in humans
  98. Impact of Acutely Increased Endogenous-and Exogenous Ketone Bodies on FGF21 Levels in Humans
  99. FGF21-FGFR4 signaling in cardiac myocytes promotes concentric cardiac hypertrophy in mouse models of diabetes
  100. Mesenchymal stem cells modified by FGF21 and GLP1 ameliorate lipid metabolism while reducing blood glucose in type 2 diabetic mice
  101. Protein-carbohydrate interaction effects on energy balance, FGF21, IGF-1, and hypothalamic gene expression in rats
  102. Dietary induction of obesity and insulin resistance is associated with changes in FGF21 DNA methylation in liver of mice
  103. Hepatic Hedgehog Signaling Participates in the Crosstalk between Liver and Adipose Tissue in Mice by Regulating FGF21
  104. Combined genetic deletion of GDF15 and FGF21 has modest effects on body weight, hepatic steatosis and insulin resistance in high fat fed mice
  105. Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2
  106. Subcutaneous delivery of FGF21 mRNA therapy reverses obesity, insulin resistance, and hepatic steatosis in diet-induced obese mice
  107. Deficiency of Cathelicidin Attenuates High-Fat Diet Plus Alcohol-Induced Liver Injury through FGF21/Adiponectin Regulation
  108. Lycopene attenuates oxidative stress-induced hepatic dysfunction of insulin signal transduction: involvement of FGF21 and mitochondria
  109. Plasma Tsukushi Concentration Is Associated with High Levels of Insulin and FGF21 and Low Level of Total Cholesterol in a General Population without Medication
  110. Therapeutic effect and mechanism of combined use of FGF21 and insulin on diabetic nephropathy
  111. FGF21 alleviates acute liver injury by inducing the SIRT1‐autophagy signalling pathway
  112. Association of Elevated Plasma FGF21 and Activated FGF21 Signaling in Visceral White Adipose Tissue and Improved Insulin Sensitivity in Gestational …
  113. Effects of feeding frequency on growth performance, feed intake, metabolism and expression of FGF21 in grass carp (Ctenopharyngodon idellus)
  114. FGF21 outperforms GDF15 as a diagnostic biomarker of mitochondrial disease in children
  115. Plasma FGF21 concentrations and spontaneous self-selection of protein suggest that 15% protein in the diet may not be enough for male adult rats
  116. Acute deletion of the FOXO1-dependent hepatokine FGF21 does not alter basal glucose homeostasis or lipolysis in mice
  117. The Roles of FGF21 and ALCAT1 in Aerobic Exercise-Induced Cardioprotection of Postmyocardial Infarction Mice
  118. Rats self-select a constant protein-to-carbohydrate ratio rather than a constant protein-to-energy ratio and have low plasma FGF21 concentrations
  119. FGF21 alleviates pulmonary hypertension by inhibiting mTORC1/EIF4EBP1 pathway via H19
  120. Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine …
  121. Sitagliptin reduces FAP-activity and increases intact FGF21 levels in patients with newly detected glucose abnormalities
  122. FGF21 regulates alcohol intake: New hopes on the rise for alcohol use disorder treatment?
  123. Changes in hepatic triglyceride content with the activation of ER stress and increased FGF21 secretion during pregnancy
  124. Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis
  125. Recombinant FGF21 Attenuates Polychlorinated Biphenyl-Induced NAFLD/NASH by Modulating Hepatic Lipocalin-2 Expression
  126. ZFP36L1 regulates FGF21 mRNA turnover and modulates alcoholic hepatic steatosis and inflammation in mice
  127. Neuroprotective Effect of Lentivirus-Mediated FGF21 Gene Delivery in Experimental Alzheimer’s Disease is Augmented when Concerted with Rapamycin
  128. Efruxifermin, a long‐acting Fc‐fusion FGF21 analogue, reduces body weight gain but does not increase sympathetic tone or urine volume in Sprague Dawley rats
  129. Aerobic exercise regulates FGF21 and NLRP3 inflammasome-mediated pyroptosis and inhibits atherosclerosis in mice
  130. Another Kid on the Block: Long-acting FGF21 Analogue to Treat Dyslipidemia and Fatty Liver
  131. Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis
  132. FGF21 normalizes plasma glucose in mouse models of type 1 diabetes and insulin receptor dysfunction
  133. FGF21 attenuates pulmonary arterial hypertension via downregulation of miR‐130, which targets PPARγ
  134. Liraglutide regulates lipid metabolism via FGF21-LKB1-AMPK-ACC1 pathway in white adipose tissues and macrophage of type 2 diabetic mice
  135. Single Nucleotide Polymorphisms in Close Proximity to the Fibroblast Growth Factor 21 (FGF21) Gene Found to Be Associated with Sugar Intake in a Swedish …
  136. Pyruvate Upregulates Hepatic FGF21 Expression by Activating PDE and Inhibiting cAMP–Epac–CREB Signaling Pathway
  137. Plasma FGF21 concentrations are regulated by glucose independently of insulin and GLP-1 in lean, healthy humans
  138. Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric …
  139. The effect of FGF21 and its genetic variants on food and drug cravings, adipokines and metabolic traits
  140. Dynamic effects of dietary protein restriction on body weights, food consumption, and protein preference in C57BL/6J and FGF21‐KO mice
  141. Association between FGF19, FGF21 and lipocalin-2, and diabetes progression in PCOS
  142. Attenuation of FGF21 signalling might aggravate the impairment of glucose homeostasis during the high sucrose diet induced transition from prediabetes to …
  143. Hepatocyte-Secreted Autotaxin Exacerbates Nonalcoholic Fatty Liver Disease Through Autocrine Inhibition of the PPARα/FGF21 Axis
  144. An FGF21-like gene from swamp eel (Monopterus albus): Recombinant expression and its potential roles in glucose and lipid homeostasis
  145. … SIRT1 to regulate cell apoptosis, inflammatory response, and oxidative stress in acute myocardial infarction in rats via modulation of the FGF21/CREB/PGC1α pathway
  146. FGF21 and chronic kidney disease
  147. Potential of Hibiscus sabdariffa Linn. in managing FGF21 resistance in diet‐induced‐obesity rats via miR‐34a regulation
  148. High baseline FGF21 levels are associated with poor glucose-lowering efficacy of exenatide in patients with type 2 diabetes
  149. Dimethyl itaconate attenuates palmitate-induced insulin resistance in skeletal muscle cells through the AMPK/FGF21/PPARδ-mediated suppression of inflammation
  150. FGF21 Reduces Lipid Accumulation in Bovine Hepatocytes by Enhancing Lipid Oxidation and Reducing Lipogenesis via AMPK Signaling
  151. TWIST2 inhibits EMT and induces oxidative stress in lung cancer cells by regulating the FGF21-mediated AMPK/mTOR pathway
  152. Elevated serum FGF21 predicts the major adverse cardiovascular events in STEMI patients after emergency percutaneous coronary intervention
  153. DPP-4 inhibitor induces FGF21 expression via sirtuin 1 signaling and improves myocardial energy metabolism
  154. Non-Alcoholic Steatohepatitis Severity Associates with FGF21 Level and Kidney Glucose Uptake
  155. … -Cas9-based genome-wide screening identified novel targets for treating sorafenib-resistant hepatocellular carcinoma: a cross-talk between FGF21 and the NRF2 …
  156. Fatty Acid Desaturase 1 Influences Hepatic Lipid Homeostasis by Modulating the PPARα‐FGF21 Axis
  157. SNAI1 is upregulated during muscle regeneration and represses FGF21 and ATF3 expression by directly binding their promoters
  158. Production of active human FGF21 using tobacco mosaic virus-based transient expression system
  159. Circulating FGF21 vs. Stress Markers in Girls during Childhood and Adolescence, and in Their Caregivers: Intriguing Inter-Relations between Overweight/Obesity …
  160. Increased fibroblast growth factor 21 (FGF21) concentration in early second trimester amniotic fluid and its association with fetal growth
  161. Epigallocatechin-3-gallate ameliorates hepatic damages by relieve FGF21 resistance and promotion of FGF21–AMPK pathway in mice fed a high fat diet
  162. Dietary Essential Amino Acid Restriction Promotes Hyperdipsia via Hepatic FGF21
  163. Refined-JinQi-JiangTang tablet ameliorates hypertension through activation of FGF21/FGFR1 axis in fructose-fed rats
  164. Non-Alcoholic Fatty Liver Disease in Long-Term Type 2 Diabetes: Role of rs738409 PNPLA3 and rs499765 FGF21 Polymorphisms and Serum Biomarkers
  165. Fibroblast Growth Factor 21 (FGF21) Administration Sex-Specifically Affects Blood Insulin Levels and Liver Steatosis in Obese Ay Mice
  166. FGF21 contributes to metabolic improvements elicited by combination therapy with exenatide and pioglitazone in patients with type 2 diabetes
  167. Visceral adipose tissue-directed FGF21 gene therapy improves metabolic and immune health in BTBR mice
  168. Alternate-day fasting alleviates high fat diet induced non-alcoholic fatty liver disease through controlling PPARα/FGF21 signaling
  169. Serum levels of the cold stress hormones FGF21 and GDF-15 after cardiac arrest in infants and children enrolled in single center therapeutic hypothermia clinical trials
  170. Alcoholic fatty liver is blunted by rFGF21 administration in mice lacking adipose FGFR1: The role of FGF21 in PPARα-mediated regulation of adipose tissue mass
  171. The role of increased FGF21 in VLDL-TAG secretion and thermogenic gene expression in mice under protein malnutrition
  172. Sustained reduction of triglyceride and LDL cholesterol from single administration of the novel long-acting FGF21 analogue 0499
  173. FGF21 alleviates chronic inflammatory injury in the aging process through modulating polarization of macrophages
  174. KLF4 downregulates FGF21 to activate inflammatory injury and oxidative stress of LPS‑induced ATDC5 cells via SIRT1/NF‑κB/p53 signaling
  175. Does an increase in serum FGF21 level predict 28-day mortality of critical patients with sepsis and ARDS?
  176. Changes and significance of serum FGF21 in children with primary nephrotic syndrome and chronic renal failure
  177. Reduced triglycerides and LDL cholesterol from once-weekly administration of the well-tolerated novel FGF21 analogue 0499
  178. The Regulation Mechanism of different hair types in Inner Mongolia Cashmere Goat based on PI3K-AKT Pathway and FGF21
  179. Estradiol-dependent and independent effects of FGF21 in obese female mice
  180. Fibroblast growth factor 21 (FGF21) is increased in MDD and interacts with body mass index (BMI) to affect depression trajectory
  181. β-Hydroxybutyrate upregulates FGF21 expression through inhibition of histone deacetylases in hepatocytes
  182. FGF21 promotes wound healing of rat brain microvascular endothelial cells through facilitating TNF-α-mediated VEGFA and ERK1/2 signaling pathway
  183. FGF21 has a sex-specific role in calorie-restriction-induced beiging of white adipose tissue in mice
  184. FGF21 improves LPS-induced pulmonary microvascular endothelial cell dysfunction and inflammatory response through SIRT1-mediated NF-κB deacetylation
  185. Autotaxin, PPARs, and FGF21: An Eye Opener for Progressive Liver Disease?
  186. Author Correction: Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice
  187. FGF21 Counteracts Alcohol Intoxication by Activating Noradrenergic Neurons
  188. hsa_circ_0001955 Promotes Colorectal Cancer Progression by Regulating miR-583/FGF21 Axis
  189. Src homology 3 domain binding kinase 1 protects against hepatic steatosis and insulin resistance through the Nur77–FGF21 pathway
  190. Relationship between Serum FGF21 and vWF Expression and Carotid Atherosclerosis in Elderly Patients with Hypertension
  191. FGF21 defines a potential cardio-hepatic signaling circuit in human heart failure
  192. GATA2/FGF21 Axis Regulates the Effects of High Glucose on the Apoptosis, Autophagy and Oxidative Stress of Human Umbilical Vein Endothelial Cell via PI3K/AKT …
  193. Autocrine FGF21 signalling promotes beiging
  194. Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling
  195. Circulating myokines IL-6, IL-15 and FGF21 response to training is altered by exercise type but not by menopause in women with obesity
  196. Cardiovascular autonomic reflex tests and serum FGF21 levels in overweight and normal-weight men and women
  197. Protein preference and elevated plasma FGF21 induced by dietary protein restriction is similar in both male and female mice
  198. Involvement of FGF21 in pulmonary fibrosis
  199. Serum FGF21 levels are altered with various factors including lifestyle behaviors
  200. How a metabolic hormone, FGF21 (fibroblast growth factor 21) impacts reproduction
  201. FGF21 Response Varies by Sugar Type and is Associated with Body Weight, Dietary Added Sugar, and Neural Signaling in Humans
  202. Increased Plasma FGF21 and Activated FGF21 Signaling in Adipose Tissue and Its Possible Association With Insulin Sensitivity in Specific GDM Subtype
  203. Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2. Cells 2022, 11, 567
  204. Early warning for inactive ovaries based on liver function index, serum MDA, IL-6, FGF21 and ANGPTL8 in dairy cows
  205. Fibroblast growth factor 21 (FGF21) is a sensitive marker of osteoporosis in haemodialysis patients: a cross-sectional observational study
  206. Activating Effects of the Bioactive Compounds From Coffee By-Products on FGF21 Signaling Modulate Hepatic Mitochondrial Bioenergetics and Energy …
  207. Effect of aquatic training on serum Fetuin-A, ANGPTL4 and FGF21 levels in type 2 diabetic obese women
  208. Effect of Exercise Training on Serum FGF21 Level in Adults with Metabolic Disorders, A Meta-Analysis
  209. … -Transcriptome Sequencing Reveals CeRNA Regulatory Network of mRNAs, lncRNAs, miRNAs and circRNAs in Pulmonary Hypertension Treated with FGF21
  210. FGF21 Is a Potential Therapeutic for Morphine Preference and Dependence
  211. Correlation between Serum FGF21 Level and Diabetic Peripheral Neuropathy
  212. 115-LB: Liver-Derived FGF21 Mediates the Promoting Effect of Glucagon Receptor Antagonism on Beta-Cell Regeneration in Type 2 Diabetic Mice
  213. FGF21 Promotes Proliferation and Estradiol Synthesis in Porcine Granulosa Cells
  214. Virtual Reality Alleviates Post-Stroke Depression by Regulating FGF21
  215. Homocysteine-induced endoplasmic reticulum stress activates FGF21 via CREBH, resulting in browning and atrophy of white adipose tissue in Bhmt knockout mice
  216. Endogenous GDF15 and FGF21 additively alleviate hepatic steatosis and insulin resistance in obese mice.
  217. Population Pharmacokinetics (PK) and Pharmacodynamics (PD) of BIO89-100, a Novel GlycoPEGylated FGF21, in a Phase 1b/2a POC Study in Nonalcoholic …
  218. Obesity-resistance of UCP1-deficient mice associates with sustained FGF21 sensitivity in inguinal adipose tissue
  219. … 21 (FGF21) is increased in individuals with gestational diabetes mellitus (GDM) after 24 gestational weeks. However, it is unknown whether the increase in FGF21 …
  220. Pharmacokinetics of FGF21-164 fusion protein in mice using UHPLC-MS/MS method
  221. Effects of different exercise on liver lipid accumulation and FGF21 secretion in obese rats
  222. Association of Common Variants of FGF21 Gene Polymorphism Rs499765 and Rs838133 with Type 2 Diabetes Mellitus in Iraqi Population
  223. The effect of high Intensity Interval Training (HIIT) on adipsin, FGF21 and ABCA1 indices in obese men
  224. Design and characterization of a FGF1-FGF21 chimeric protein with increased stability and enhanced antidiabetic activities.
  225. Erratum. Hepatic CPT1A Facilitates Liver-Adipose Cross Talk via Induction of FGF21 in Mice. Diabetes 2022; 71: 31-42
  226. 144-OR: Adipose Modeling of FGF21 Signaling Mutations in a Severe Insulin Resistance Syndrome
  227. MiR-26b-5p Promotes Osteogenesis of Bone Mesenchymal Stem Cells via Suppressing FGF21
  228. The effect of special training exercise on FGF21 expression and FGFR-1 among CABG patients
  229. Multi-year participation in prolonged athletic training is associated with higher risk of chronic fatigue and abnormal serum FGF21 levels in professional athletes
  230. LLF580, an FGF21 Analog, Reduces Triglycerides and Hepatic Fat in obese persons with modestly elevated triglycerides: A 12 Week Randomized Double Blind …
  231. Abstract TP235: Delayed FGF21 Administration Improves Cerebrovascular Remodeling And White Matter Repair After Focal Stroke In Diabetic Mice
  232. FGF21 restores hippocampual mitochondrial dysfunction via enhancing Nrf2/HO-1 and AMPK/SirT1/PGC-1α signaling pathways to alleviate chronic …
  233. … Select Abstract: The Beneficial Effect of Fenofibrate on Diabetic Retinopathy Is Influenced by PPARA Genetic Variability and Is Mediated by an Increase in FGF21 …
  234. Effect of Eight Weeks of Aerobic Exercise with Ginger Supplementation on FGF21, Irisin and Insulin Resistance in Women with Type 2 Diabetes
  235. The Hepatokine FGF21 Increases the Human Spermatozoa Motility
  236. Homocysteine-induced endoplasmic reticulum stress activates FGF21 via CREBH, resulting in browning and atrophy of white adipose tissue in Bhmt knockout mice
  237. FGF21 Levels and Bone Mineral Density in Metabolically Healthy and Metabolically Unhealthy Obese Children
  238. The association between FGF21 and diabetic erectile dysfunction: Evidence from clinical and animal studies
  239. FGF21 is released during increased lipogenesisis state following rapid-onset radioiodine-induced hypothyroidism
  240. 1379-P: Combination of FGF21 and ß3-Adrenergic Treatment in Obese Mice
  241. FGF21 Promotes Senescence, Apoptosis, and Extracellular Matrix Degradation in Osteoarthritis via the AMPK Signaling Pathway
  242. 286-OR: FGF21 Decreases Hepatic Triglycerides in a Weight Loss-Independent but Sex-Dependent Manner
  243. Close association between lifestyle and circulating FGF21 levels: A systematic review and meta-analysis
  244. FGF21/FGFR1-β-KL Cascade in Cardiomyocytes Modulates Angiogenesis and Inflammation Under Metabolic Stress
  245. FGF21 Normalizes Plasma Glucose in Mouse Models of Type 1 Diabetes and Insulin Receptor Dysfunction John L Diener1, 2, Sarah Mowbray1, Waan-Jeng …
  246. Serum FGF21 Levels Predict the MACE in Patients With Myocardial Infarction After Coronary Artery Bypass Graft Surgery
  247. Multi-organ FGF21-FGFR1 signaling in metabolic health and disease
  248. Corrigendum to” Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance”[The Journal of Nutritional Biochemistry 57 (2018) …
  249. Circulating FGF21 and GDF15 as Biomarkers for Screening, Diagnosis, and Severity Assessment of Primary Mitochondrial Disorders in Children
  250. (+)-Dehydrovomifoliol Alleviates Oleic Acid-Induced Lipid Accumulation in HepG2 Cells via the PPARα–FGF21 Pathway
  251. The effect of 8 weeks of high-intensity interval training (HIIT) Tribulus terrestris supplementation on serum BDNF and FGF21 in obese women
  252. 212-LB: Therapeutic Effect of a Novel Long-Acting GLP-1/GCG/FGF21/Anticytokine Tetra-Specific Liver Microenvironment-Targeting Drug (OGB21502) in MCD …
  253. Maternal High-Fat Diet Alters the Characteristics of Astrocytes and Worsens the Outcome of Stroke in Rat Offspring, Which Improves After FGF21 …
  254. 211-LB: Antifibrotic Effect of a Novel Long-Acting GLP-1/GCG/FGF21/Anti-Cytokine Tetra-Specific Liver Microenvironment-Targeting Drug (OGB21502) in CCl4 …
  255. FGF21 contributes to metabolic improvements elicited by combination therapy with exenatide and pioglitazone in patients with type 2 diabetes
  256. Hepatic Stearoyl-CoA desaturase deficiency-mediated induction of the insulin-like growth factor-binding protein 1 requires FGF21.
  257. Examining the potential of Urolithins to induce hepatic Fibroblast Growth Factor 21 (FGF21) Expression and Release in High Fat Diet Induced Obesity
  258. 208-LB: Peripheral CB1 Inverse Agonism Improves Metabolism in DIO Mice Independent of Hepatic FGF21
  259. Understanding the physiology of FGF21
  260. Inventing new medicines: the FGF21 story
  261. The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic
  262. FGF21 is an Akt-regulated myokine
  263. FGF21 Requires βklotho to Act In Vivo
  264. FGF21 and cardiac physiopathology
  265. Going back to the biology of FGF21: new insights
  266. The effects of LY2405319, an FGF21 analog, in obese human subjects with type 2 diabetes
  267. PPARα is a key regulator of hepatic FGF21
  268. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
  269. FGF21 reloaded: challenges of a rapidly growing field
  270. FGF21 as a stress hormone: the roles of FGF21 in stress adaptation and the treatment of metabolic diseases
  271. A dozen years of discovery: insights into the physiology and pharmacology of FGF21
  272. FGF21 as a hepatokine, adipokine, and myokine in metabolism and diseases
  273. Different roles of N‐and C‐termini in the functional activity of FGF21
  274. FGF21 is an endocrine signal of protein restriction
  275. Discrete aspects of FGF21 in vivo pharmacology do not require UCP1
  276. A new frontier in FGF21 biology
  277. FGF21-based pharmacotherapy–potential utility for metabolic disorders
  278. FGF21: a novel prospect for the treatment of metabolic diseases
  279. FGF21 regulates sweet and alcohol preference
  280. FGF21 revolutions: recent advances illuminating FGF21 biology and medicinal properties
  281. Thermogenic activation induces FGF21 expression and release in brown adipose tissue
  282. FGF21 as Modulator of Metabolism in Health and Disease
  283. Interplay between FGF21 and insulin action in the liver regulates metabolism
  284. Defining the nutritional and metabolic context of FGF21 using the geometric framework
  285. Paradoxical regulation of human FGF21 by both fasting and feeding signals: is FGF21 a nutritional adaptation factor?
  286. FGF21 and the late adaptive response to starvation in humans
  287. FGF21 regulates metabolism through adipose-dependent and-independent mechanisms
  288. Cellular mechanisms by which FGF21 improves insulin sensitivity in male mice
  289. FGF21 N-and C-termini play different roles in receptor interaction and activation
  290. FGF21: a missing link in the biology of fasting
  291. Increased serum FGF21 levels in patients with nonalcoholic fatty liver disease
  292. Activation of Liver FGF21 in hepatocarcinogenesis and during hepatic stress
  293. Physiological and pharmacological roles of FGF21 in cardiovascular diseases
  294. The fasting polypeptide FGF21 can enter brain from blood
  295. FGF21 and the physiological regulation of macronutrient preference
  296. TNF-α represses β-Klotho expression and impairs FGF21 action in adipose cells: involvement of JNK1 in the FGF21 pathway
  297. Long-term cold adaptation does not require FGF21 or UCP1
  298. Inhibition of growth hormone signaling by the fasting-induced hormone FGF21
  299. FGF21 regulates metabolism and circadian behavior by acting on the nervous system
  300. Acute exercise induces FGF21 expression in mice and in healthy humans
  301. Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice
  302. Novel locus including FGF21 is associated with dietary macronutrient intake
  303. Lack of overt FGF21 resistance in two mouse models of obesity and insulin resistance
  304. Autophagy deficiency leads to protection from obesity and insulin resistance by inducing FGF21 as a mitokine
  305. Serum levels of the adipokine FGF21 depend on renal function
  306. Pharmacologic effects of FGF21 are independent of the “browning” of white adipose tissue
  307. The circulating metabolic regulator FGF21 is induced by prolonged fasting and PPARα activation in man
  308. FGF21 contributes to neuroendocrine control of female reproduction
  309. Targeting FGF21 for the treatment of nonalcoholic steatohepatitis
  310. FGF21 is an exocrine pancreas secretagogue
  311. Understanding the Physical Interactions in the FGF21/FGFR/β‐Klotho Complex: Structural Requirements and Implications in FGF21 Signaling
  312. Direct effects of FGF21 on glucose uptake in human skeletal muscle: implications for type 2 diabetes and obesity
  313. Fundamentals of FGF19 & FGF21 Action In Vitro and In Vivo
  314. FGF21 is a biomarker for mitochondrial translation and mtDNA maintenance disorders
  315. FGF21 is a sugar-induced hormone associated with sweet intake and preference in humans
  316. FGF21 acts centrally to induce sympathetic nerve activity, energy expenditure, and weight loss
  317. Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21
  318. Fatty liver and FGF21 physiology
  319. FGF21 attenuates lipolysis in human adipocytes–a possible link to improved insulin sensitivity
  320. Irisin and FGF21 are cold-induced endocrine activators of brown fat function in humans
  321. FGF21 gene therapy as treatment for obesity and insulin resistance
  322. FGF21 induces PGC-1α and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response
  323. Serum FGF21 levels are associated with brown adipose tissue activity in humans
  324. Treating diabetes and obesity with an FGF21-mimetic antibody activating the βKlotho/FGFR1c receptor complex
  325. FGF21 regulates PGC-1α and browning of white adipose tissues in adaptive thermogenesis
  326. FGF21-receptor agonists: an emerging therapeutic class for obesity-related diseases
  327. Fructose ingestion acutely stimulates circulating FGF21 levels in humans
  328. FGF21 mediates the lipid metabolism response to amino acid starvation
  329. Novel insights into the cardio-protective effects of FGF21 in lean and obese rat hearts
  330. The roles of FGF21 in atherosclerosis pathogenesis
  331. LY2405319, an engineered FGF21 variant, improves the metabolic status of diabetic monkeys
  332. FGF21 mimetic shows therapeutic promise
  333. Dynamic change of serum FGF21 levels in response to glucose challenge in human
  334. An FGF21-adiponectin-ceramide axis controls energy expenditure and insulin action in mice
  335. FGF21 takes a fat bite
  336. FGF21 signals protein status to the brain and adaptively regulates food choice and metabolism
  337. The regulation of FGF21 gene expression by metabolic factors and nutrients
  338. Fibroblast growth factors in cardiovascular disease: The emerging role of FGF21
  339. Rationale-based engineering of a potent long-acting FGF21 analog for the treatment of type 2 diabetes
  340. Stressed liver and muscle call on adipocytes with FGF21
  341. FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting
  342. Circulating FGF21 is liver derived and enhances glucose uptake during refeeding and overfeeding
  343. Regulation of longevity by FGF21: Interaction between energy metabolism and stress responses
  344. Defining “FGF21 Resistance” during obesity: Controversy, criteria and unresolved questions
  345. Tissue-specific expression of βKlotho and fibroblast growth factor (FGF) receptor isoforms determines metabolic activity of FGF19 and FGF21
  346. Endocrine protection of ischemic myocardium by FGF21 from the liver and adipose tissue
  347. FGF21 as an endocrine regulator in lipid metabolism: from molecular evolution to physiology and pathophysiology
  348. The FGF21–adiponectin axis in controlling energy and vascular homeostasis
  349. FGF21 promotes metabolic homeostasis via white adipose and leptin in mice
  350. FGF21 mediates endocrine control of simple sugar intake and sweet taste preference by the liver
  351. FGF21 as a therapeutic reagent
  352. Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models—association with liver and adipose tissue effects
  353. Serum FGF21 levels in adult m. 3243A> G carriers: clinical implications
  354. Glucocorticoids regulate the metabolic hormone FGF21 in a feed-forward loop
  355. Circulating FGF21 levels in human health and metabolic disease
  356. Hepatic FGF21 expression is induced at birth via PPARα in response to milk intake and contributes to thermogenic activation of neonatal brown fat
  357. Circulating FGF21 proteolytic processing mediated by fibroblast activation protein
  358. The role of FGF21 in type 1 diabetes and its complications
  359. A novel approach to improve the function of FGF21
  360. Inhibition of lipolysis may contribute to the acute regulation of plasma FFA and glucose by FGF21 in ob/ob mice
  361. Aging is associated with increased FGF21 levels but unaltered FGF21 responsiveness in adipose tissue
  362. A long-acting FGF21 molecule, PF-05231023, decreases body weight and improves lipid profile in non-human primates and type 2 diabetic subjects
  363. Plasma FGF21 is elevated by the intense lipid mobilization of lactation
  364. FGF21 is an insulin-dependent postprandial hormone in adult humans
  365. SGLT2 inhibition reprograms systemic metabolism via FGF21-dependent and-independent mechanisms
  366. Skeletal muscle mitochondrial uncoupling drives endocrine cross-talk through the induction of FGF21 as a myokine
  367. Circulating FGF21 levels are progressively increased from the early to end stages of chronic kidney diseases and are associated with renal function in …
  368. Glucose induces FGF21 mRNA expression through ChREBP activation in rat hepatocytes
  369. FGF21: an emerging therapeutic target for non-alcoholic steatohepatitis and related metabolic diseases
  370. Liver derived FGF21 maintains core body temperature during acute cold exposure
  371. FGF21-mediated improvements in glucose clearance require uncoupling protein 1
  372. Opposite alterations in FGF21 and FGF19 levels and disturbed expression of the receptor machinery for endocrine FGFs in obese patients
  373. Research perspectives on the regulation and physiological functions of FGF21 and its association with NAFLD
  374. Long-acting FGF21 has enhanced efficacy in diet-induced obese mice and in obese rhesus monkeys
  375. KLB is associated with alcohol drinking, and its gene product β-Klotho is necessary for FGF21 regulation of alcohol preference
  376. Nrf2 represses FGF21 during long-term high-fat diet–induced obesity in mice
  377. FGF21: The center of a transcriptional nexus in metabolic regulation
  378. FGF21 is a hormonal mediator of the human “thrifty” metabolic phenotype
  379. A critical role for ChREBP-mediated FGF21 secretion in hepatic fructose metabolism
  380. Endogenous FGF21-signaling controls paradoxical obesity resistance of UCP1-deficient mice
  381. FGF21 analogs of sustained action enabled by orthogonal biosynthesis demonstrate enhanced antidiabetic pharmacology in rodents
  382. Therapeutic potential of the endocrine fibroblast growth factors FGF19, FGF21 and FGF23
  383. Metabolic responses to dietary protein restriction require an increase in FGF21 that is delayed by the absence of GCN2
  384. Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
  385. Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action
  386. FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation
  387. FGF21 lowers plasma triglycerides by accelerating lipoprotein catabolism in white and brown adipose tissues
  388. Leptin as a Potential Regulator of FGF21
  389. Metformin stimulates FGF21 expression in primary hepatocytes
  390. mTORC1 is a major regulatory node in the FGF21 signaling network in adipocytes
  391. PGC-1α negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erbα axis
  392. Effects of insulin and exercise training on FGF21, its receptors and target genes in obesity and type 2 diabetes
  393. Exercise alleviates obesity-induced metabolic dysfunction via enhancing FGF21 sensitivity in adipose tissues
  394. Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates
  395. FGF21 signals to glutamatergic neurons in the ventromedial hypothalamus to suppress carbohydrate intake
  396. Differential specificity of endocrine FGF19 and FGF21 to FGFR1 and FGFR4 in complex with KLB
  397. Pancreatitis is an FGF21-deficient state that is corrected by replacement therapy
  398. ATF4-and CHOP-dependent induction of FGF21 through endoplasmic reticulum stress
  399. FGF21 is required for cardiac remodeling in pregnancy
  400. iNKT cells induce FGF21 for thermogenesis and are required for maximal weight loss in GLP1 therapy
  401. Dietary methionine restriction reduces inflammation independent of FGF21 action
  402. FGF21 Is Increased by Inflammatory Stimuli and Protects Leptin-Deficient ob/ob Mice from the Toxicity of Sepsis
  403. FGF21 as a mediator of adaptive responses to stress and metabolic benefits of anti-diabetic drugs
  404. FGF21 activates AMPK signaling: impact on metabolic regulation and the aging process
  405. Metabolic actions of FGF21: molecular mechanisms and therapeutic implications
  406. FGF21 attenuates pathological myocardial remodeling following myocardial infarction through the adiponectin-dependent mechanism
  407. FGF21 mediates the thermogenic and insulin-sensitizing effects of dietary methionine restriction but not its effects on hepatic lipid metabolism
  408. Increased FGF21 plasma levels in humans with sepsis and SIRS
  409. The PPARα-FGF21 hormone axis contributes to metabolic regulation by the hepatic JNK signaling pathway
  410. Molecular Hydrogen Improves Obesity and Diabetes by Inducing Hepatic FGF21 and Stimulating Energy Metabolism in db/db Mice
  411. A specific ChREBP and PPARα cross-talk is required for the glucose-mediated FGF21 response
  412. An overview of FGF19 and FGF21: the therapeutic role in the treatment of the metabolic disorders and obesity
  413. FGF19 and FGF21 for the treatment of NASH—two sides of the same coin? Differential and overlapping effects of FGF19 and FGF21 from mice to human
  414. Rush to the fire: FGF21 extinguishes metabolic stress, metaflammation and tissue damage
  415. Impaired mitochondrial fat oxidation induces FGF21 in muscle
  416. FGF21 increases water intake, urine output and blood pressure in rats
  417. Obesity is a fibroblast growth factor 21 (FGF21)-resistant state
  418. Integrated stress response stimulates FGF21 expression: Systemic enhancer of longevity
  419. Plasma FGF21 displays a circadian rhythm during a 72‐h fast in healthy female volunteers
  420. The lipid sensor GPR120 promotes brown fat activation and FGF21 release from adipocytes
  421. Circadian expression of FGF21 is induced by PPARα activation in the mouse liver
  422. A long‐acting FGF21 alleviates hepatic steatosis and inflammation in a mouse model of non‐alcoholic steatohepatitis partly through an FGF21‐adiponectin‐IL17A …
  423. FGF21 attenuates pulmonary fibrogenesis through ameliorating oxidative stress in vivo and in vitro
  424. Low protein-induced increases in FGF21 drive UCP1-dependent metabolic but not thermoregulatory endpoints
  425. FGF21 acts as a negative regulator of bile acid synthesis
  426. FGF21 deficiency is associated with childhood obesity, insulin resistance and hypoadiponectinaemia: the BCAMS Study
  427. FGF19 subfamily members: FGF19 and FGF21
  428. Metformin-induced inhibition of the mitochondrial respiratory chain increases FGF21 expression via ATF4 activation
  429. The FGF21 receptor signaling complex: Klothoβ, FGFR1c, and other regulatory interactions
  430. FGF21 protects myocardial ischemia-reperfusion injury through reduction of miR-145-mediated autophagy
  431. The hormone FGF21 stimulates water drinking in response to ketogenic diet and alcohol
  432. Serum FGF21 levels are increased in newly diagnosed type 2 diabetes with nonalcoholic fatty liver disease and associated with hsCRP levels independently
  433. High-level expression and purification of soluble recombinant FGF21 protein by SUMO fusion in Escherichia coli
  434. Activation of mTORC1 in skeletal muscle regulates whole-body metabolism through FGF21
  435. FGF21 mediates mesenchymal stem cell senescence via regulation of mitochondrial dynamics
  436. Homeostatic sensing of dietary protein restriction: a case for FGF21
  437. Plasma FGF21 levels are increased in patients with hypothyroidism independently of lipid profile
  438. FGF21 response to critical illness: effect of blood glucose control and relation with cellular stress and survival
  439. Development of a novel long-acting antidiabetic FGF21 mimetic by targeted conjugation to a scaffold antibody
  440. Regulation of FGF21 expression and secretion by retinoic acid receptor-related orphan receptor α
  441. Hepatic insulin resistance and increased hepatic glucose production in mice lacking FGF21
  442. FGF21 ameliorates nonalcoholic fatty liver disease by inducing autophagy
  443. Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans
  444. Plasma FGF21 levels in obese patients undergoing energy-restricted diets or bariatric surgery: a marker of metabolic stress?
  445. Glucagon stimulates hepatic FGF21 secretion through a PKA-and EPAC-dependent posttranscriptional mechanism
  446. FGF21 is essential for haematopoiesis in zebrafish
  447. A high circulating FGF21 level as a prognostic marker in patients with acute myocardial infarction
  448. Polyethylene glycol modified FGF21 engineered to maximize potency and minimize vacuole formation
  449. Triclosan leads to dysregulation of the metabolic regulator FGF21 exacerbating high fat diet-induced nonalcoholic fatty liver disease
  450. Peripherally derived FGF21 promotes remyelination in the central nervous system
  451. An engineered FGF21 variant, LY2405319, can prevent non-alcoholic steatohepatitis by enhancing hepatic mitochondrial function
  452. FGF21 expression and release in muscle cells: involvement of MyoD and regulation by mitochondria-driven signalling
  453. Exercise-induced secretion of FGF21 and follistatin are blocked by pancreatic clamp and impaired in type 2 diabetes
  454. The autocrine role of FGF21 in cultured adipocytes
  455. Fasting-induced FGF21 signaling activates hepatic autophagy and lipid degradation via JMJD3 histone demethylase
  456. ANGPTL6 expression is coupled with mitochondrial OXPHOS function to regulate adipose FGF21
  457. FGF21 resistance is not mediated by downregulation of beta-klotho expression in white adipose tissue
  458. Liver fat but not other adiposity measures influence circulating FGF21 levels in healthy young adult twins
  459. parameters, characteristics, and criteria for defining the term “FGF21 resistance”
  460. FGF21 attenuates high-fat diet-induced cognitive impairment via metabolic regulation and anti-inflammation of obese mice
  461. FGF19, FGF21, and an FGFR1/β-Klotho-activating antibody act on the nervous system to regulate body weight and glycemia
  462. FGF21 conducts a metabolic orchestra and fat is a key player
  463. FGF19 and FGF21 serum concentrations in human obesity and type 2 diabetes behave differently after diet-or surgically-induced weight loss
  464. Ketogenic diet impairs FGF21 signaling and promotes differential inflammatory responses in the liver and white adipose tissue
  465. Impact of short-term high-fat feeding and insulin-stimulated FGF21 levels in subjects with low birth weight and controls
  466. FGF21 improves glucose homeostasis in an obese diabetes-prone mouse model independent of body fat changes
  467. A liver-bone endocrine relay by IGFBP1 promotes osteoclastogenesis and mediates FGF21-induced bone resorption
  468. A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure
  469. Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution
  470. The FGF21-CCL11 axis mediates beiging of white adipose tissues by coupling sympathetic nervous system to type 2 immunity
  471. FGF21 prevents angiotensin II-induced hypertension and vascular dysfunction by activation of ACE2/angiotensin-(1–7) axis in mice
  472. Human HMGCS2 regulates mitochondrial fatty acid oxidation and FGF21 expression in HepG2 cell line
  473. FGF21 attenuates neurodegeneration through modulating neuroinflammation and oxidant-stress
  474. Distinct association of serum FGF21 or adiponectin levels with clinical parameters in patients with type 2 diabetes
  475. Liver-enriched transcription factor CREBH interacts with peroxisome proliferator-activated receptor α to regulate metabolic hormone FGF21
  476. Loss of FGF21 in diabetic mouse during hepatocellular carcinogenetic transformation
  477. Hepatic regulation of VLDL receptor by PPARβ/δ and FGF21 modulates non-alcoholic fatty liver disease
  478. FGF21 treatment ameliorates alcoholic fatty liver through activation of AMPK-SIRT1 pathway
  479. FGF21, energy expenditure and weight loss–how much brown fat do you need?
  480. FGF21 can be mimicked in vitro and in vivo by a novel anti-FGFR1c/β-Klotho bispecific protein
  481. Epigenetic modulation of FGF21 in the perinatal mouse liver ameliorates diet-induced obesity in adulthood
  482. FGF21 Attenuated LPS-Induced Depressive-Like Behavior via Inhibiting the Inflammatory Pathway
  483. Impact of FGF21 on glycemic control
  484. High‐protein diet more effectively reduces hepatic fat than low‐protein diet despite lower autophagy and FGF21 levels
  485. Dietary betaine supplementation increases FGF21 levels to improve glucose homeostasis and reduce hepatic lipid accumulation in mice
  486. FGF21 signaling in glutamatergic neurons is required for weight loss associated with dietary protein dilution
  487. FGF21 administration suppresses retinal and choroidal neovascularization in mice
  488. Serum FGF21 is associated with future cardiovascular events in patients with coronary artery disease
  489. Fenofibrate increases cardiac autophagy via FGF21/SIRT1 and prevents fibrosis and inflammation in the hearts of Type 1 diabetic mice
  490. Glucagon and lipid interactions in the regulation of hepatic AMPK signaling and expression of PPARα and FGF21 transcripts in vivo
  491. FGF21 alleviates neuroinflammation following ischemic stroke by modulating the temporal and spatial dynamics of microglia/macrophages
  492. Serum FGF21 levels in obese Korean children and adolescents
  493. A2A receptor activation attenuates hypertensive cardiac remodeling via promoting brown adipose tissue-derived FGF21
  494. FGF21 mitigates atherosclerosis via inhibition of NLRP3 inflammasome-mediated vascular endothelial cells pyroptosis
  495. CREBH improves diet-induced obesity, insulin resistance, and metabolic disturbances by FGF21-dependent and FGF21-independent mechanisms
  496. FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistance
  497. Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy
  498. Probiotic culture supernatant improves metabolic function through FGF21-adiponectin pathway in mice
  499. Up-regulation of Nrf2 is involved in FGF21-mediated fenofibrate protection against type 1 diabetic nephropathy
  500. FGF21 functions as a sensitive biomarker of APAP-treated patients and mice
  501. Central resistin/TLR4 impairs adiponectin signaling, contributing to insulin and FGF21 resistance
  502. Protective effect of FGF21 on type 1 diabetes-induced testicular apoptotic cell death probably via both mitochondrial-and endoplasmic reticulum stress-dependent …
  503. Serum FGF21 increases with hepatic fat accumulation in pediatric onset intestinal failure
  504. FGF21 mediates alcohol-induced adipose tissue lipolysis by activation of systemic release of catecholamine in mice [S]
  505. FGF21 underlies a hormetic response to metabolic stress in methylmalonic acidemia
  506. Autophagic control of cardiac steatosis through FGF21 in obesity-associated cardiomyopathy
  507. FGF21, a liver hormone that inhibits alcohol intake in mice, increases in human circulation after acute alcohol ingestion and sustained binge drinking at …
  508. Lactate induces FGF21 expression in adipocytes through a p38-MAPK pathway
  509. CREBH-FGF21 axis improves hepatic steatosis by suppressing adipose tissue lipolysis
  510. FGF21 protects dopaminergic neurons in Parkinson’s disease models via repression of Neuroinflammation
  511. Oncogenic KRAS reduces expression of FGF21 in acinar cells to promote pancreatic tumorigenesis in mice on a high-fat diet
  512. FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats
  513. Overexpression of β-klotho in adipose tissue sensitizes male mice to endogenous FGF21 and provides protection from diet-induced obesity
  514. Skeletal muscle increases FGF21 expression in mitochondrial disorders to compensate for energy metabolic insufficiency by activating the mTOR–YY1–PGC1α …
  515. Fasting decreases plasma FGF21 in obese subjects and the expression of FGF21 receptors in adipose tissue in both lean and obese subjects
  516. FGF21 ameliorates the neurocontrol of blood pressure in the high fructose-drinking rats
  517. FGF21 is not a major mediator for bone homeostasis or metabolic actions of PPARα and PPARγ agonists
  518. FGF21 protects the blood–brain barrier by upregulating PPARγ via FGFR1/β-klotho after traumatic brain injury
  519. Mice lacking neutral amino acid transporter B0AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control
  520. A novel Fc-FGF21 with improved resistance to proteolysis, increased affinity toward β-klotho, and enhanced efficacy in mice and cynomolgus monkeys
  521. Anti-inflammatory effects of exercise training in adipose tissue do not require FGF21
  522. Fibroblast growth factor (FGF21) protects mouse liver against D-galactose-induced oxidative stress and apoptosis via activating Nrf2 and PI3K/Akt pathways
  523. FGF21 and DPP-4 inhibitor equally prevents cognitive decline in obese rats
  524. Metformin prevents fatty liver and improves balance of white/brown adipose in an obesity mouse model by inducing FGF21
  525. FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival
  526. Hormone resistance in diabetes and obesity: insulin, leptin, and FGF21
  527. Physiological modulation of circulating FGF21: relevance of free fatty acids and insulin
  528. FGF21 protects against hypoxia injury through inducing HSP72 in cerebral microvascular endothelial cells
  529. The hepatokine FGF21 is crucial for peroxisome proliferator-activated receptor-α agonist-induced amelioration of metabolic disorders in obese mice
  530. FGF21 alleviates hepatic endoplasmic reticulum stress under physiological conditions
  531. FGF21 and the second coming of PPARγ
  532. … diet induces, whereas high-protein diet reduces hepatic FGF21 production in mice, but glucose and not amino acids up-regulate FGF21 in cultured hepatocytes
  533. Hepatic FGF21 mediates sex differences in high-fat high-fructose diet-induced fatty liver
  534. The nuclear receptor Rev-erbα regulates adipose tissue-specific FGF21 signaling
  535. Hydrodynamic delivery of FGF21 gene alleviates obesity and fatty liver in mice fed a high-fat diet
  536. HRD1‐ERAD controls production of the hepatokine FGF21 through CREBH polyubiquitination
  537. FGF21 induced by carbon monoxide mediates metabolic homeostasis via the PERK/ATF4 pathway
  538. Lack of FGF21 promotes NASH-HCC transition via hepatocyte-TLR4-IL-17A signaling
  539. Liver-derived FGF21 is essential for full adaptation to ketogenic diet but does not regulate glucose homeostasis
  540. Tanycytes regulate lipid homeostasis by sensing free fatty acids and signaling to key hypothalamic neuronal populations via FGF21 secretion
  541. Activation of cardiac AMPK-FGF21 feed-forward loop in acute myocardial infarction: Role of adrenergic overdrive and lipolysis byproducts
  542. Association between insulin resistance and impairment of FGF21 signal transduction in skeletal muscles
  543. Treatment of CIA mice with FGF21 down-regulates TH17-IL-17 axis
  544. FGF10 and FGF21 as regulators in adipocyte development and metabolism
  545. FGF21 signalling pathway and metabolic traits–genetic association analysis
  546. … enzyme-linked immunosorbent assay and ligand-binding mass spectrometry for analysis of biotransformation of protein therapeutics: application to various FGF21 …
  547. Pharmacokinetics and pharmacodynamics of PF‐05231023, a novel long‐acting FGF21 mimetic, in a first‐in‐human study
  548. Transcriptional repressor E4-binding protein 4 (E4BP4) regulates metabolic hormone fibroblast growth factor 21 (FGF21) during circadian cycles and feeding
  549. Molecular elements in FGF19 and FGF21 defining KLB/FGFR activity and specificity
  550. Interactions between FGF21 and BMP-2 in osteogenesis
  551. FGF21 is not required for glucose homeostasis, ketosis or tumour suppression associated with ketogenic diets in mice
  552. Time-imposed daily restricted feeding induces rhythmic expression of FGF21 in white adipose tissue of mice
  553. Dietary protein dilution limits dyslipidemia in obesity through FGF21-driven fatty acid clearance
  554. Serum FGF21 levels are elevated in association with lipodystrophy, insulin resistance and biomarkers of liver injury in HIV-1-infected patients
  555. Baseline HOMA IR and circulating FGF21 levels predict NAFLD improvement in patients undergoing a low carbohydrate dietary intervention for weight loss: a …
  556. Long-term caloric restriction in ApoE-deficient mice results in neuroprotection via FGF21-induced AMPK/mTOR pathway
  557. Metformin ameliorates experimental-obesity-associated autoimmune arthritis by inducing FGF21 expression and brown adipocyte differentiation
  558. Hepatic Sel1L‐Hrd1 ER‐associated degradation (ERAD) manages FGF21 levels and systemic metabolism via CREBH
  559. Pegylated FGF21 rapidly normalizes insulin-stimulated glucose utilization in diet-induced insulin resistant mice
  560. Diet polyphenol curcumin stimulates hepatic FGF21 production and restores its sensitivity in high-fat-diet–fed male mice
  561. Long-acting FGF21 inhibits retinal vascular leakage in in vivo and in vitro models
  562. FGF21 impairs adipocyte insulin sensitivity in mice fed a low-carbohydrate, high-fat ketogenic diet
  563. Physiology and Endocrinology Symposium: FGF21: Insights into mechanism of action from preclinical studies,
  564. Neuronal SIRT1 regulates macronutrient-based diet selection through FGF21 and oxytocin signalling in mice
  565. Altered GDF15 and FGF21 levels in response to strenuous exercise: a study in marathon runners
  566. FGF21 attenuates hypoxia‑induced dysfunction and apoptosis in HPAECs through alleviating endoplasmic reticulum stress
  567. Selective regulation of FGF19 and FGF21 expression by cellular and nutritional stress
  568. Hepatic posttranscriptional network comprised of CCR4–NOT deadenylase and FGF21 maintains systemic metabolic homeostasis
  569. FGF21 mimics a fasting-induced metabolic state and increases appetite in zebrafish
  570. Relationship between FGF21 and UCP1 levels under time-restricted feeding and high-fat diet
  571. Molecular Characterization and Mapping of FGF21 Gene in a Foodfish Species Asian Seabass
  572. Improved FGF21 sensitivity and restored FGF21 signaling pathway in high-fat diet/streptozotocin-induced diabetic rats after duodenal-jejunal bypass and …
  573. Targeted DNA demethylation of the FGF21 promoter by CRISPR/dCas9-mediated epigenome editing
  574. Fibroblast growth factor 21 (FGF21) promotes formation of aerobic myofibers via the FGF21‐SIRT1‐AMPK‐PGC1α pathway
  575. Early increases in serum FGF21 levels predict mortality of septic patients
  576. Head over hepatocytes for FGF21
  577. Pharmacokinetics (PK), pharmacodynamics (PD) and integrated PK/PD modeling of a novel long acting FGF21 clinical candidate PF-05231023 in diet …
  578. Additive protection by LDR and FGF21 treatment against diabetic nephropathy in type 2 diabetes model
  579. Increased plasma FGF21 level as an early biomarker for insulin resistance and metabolic disturbance in obese insulin-resistant rats
  580. Elevated FGF21 secretion, PGC-1α and ketogenic enzyme expression are hallmarks of iron–sulfur cluster depletion in human skeletal muscle
  581. Macronutrient Intake–Associated FGF21 Genotype Modifies Effects of Weight-Loss Diets on 2-Year Changes of Central Adiposity and Body Composition: The …
  582. Recombinant FGF21 protects against blood-brain barrier leakage through Nrf2 upregulation in type 2 diabetes mice
  583. FGF21 trafficking in intact human cells revealed by cryo-electron tomography with gold nanoparticles
  584. Increased serum level of FGF21 in gestational diabetes mellitus
  585. Genetic disruption of uncoupling protein 1 in mice renders brown adipose tissue a significant source of FGF21 secretion
  586. FGF21 suppresses hepatic glucose production through the activation of atypical protein kinase Cι/λ
  587. FGF21 is induced in cisplatin nephrotoxicity to protect against kidney tubular cell injury
  588. FGF21 decreases body weight without reducing food intake or bone mineral density in high-fat fed obese rhesus macaque monkeys
  589. Free fatty acids impair FGF21 action in HepG2 cells
  590. Low-protein and methionine, high-starch diets increase energy intake and expenditure, increase FGF21, decrease IGF-1, and have little effect on adiposity in mice
  591. FGF21 mimetic antibody stimulates UCP1-independent brown fat thermogenesis via FGFR1/βKlotho complex in non-adipocytes
  592. GCN2 and FGF21 are likely mediators of the protection from cancer, autoimmunity, obesity, and diabetes afforded by vegan diets
  593. A solid-phase PEGylation strategy for protein therapeutics using a potent FGF21 analog
  594. FAP finds FGF21 easy to digest
  595. Inhibition of vascular neointima hyperplasia by FGF21 associated with FGFR1/Syk/NLRP3 inflammasome pathway in diabetic mice
  596. FGF21 represses cerebrovascular aging via improving mitochondrial biogenesis and inhibiting p53 signaling pathway in an AMPK-dependent manner
  597. FGF21 promotes functional recovery after hypoxic-ischemic brain injury in neonatal rats by activating the PI3K/Akt signaling pathway via FGFR1/β-klotho
  598. Hepatic tristetraprolin promotes insulin resistance through RNA destabilization of FGF21
  599. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity
  600. FGF21 ameliorates diabetic cardiomyopathy by activating the AMPK-paraoxonase 1 signaling axis in mice
  601. FGF21 regulates insulin sensitivity following long-term chronic stress
  602. Membraneless reproducible MoS2 field-effect transistor biosensor for high sensitive and selective detection of FGF21
  603. Hepatic Crtc2 controls whole body energy metabolism via a miR-34a-FGF21 axis
  604. FGF21 induces autophagy‐mediated cholesterol efflux to inhibit atherogenesis via RACK1 up‐regulation
  605. FGF21-FGFR1 coordinates phospholipid homeostasis, lipid droplet function, and ER stress in obesity
  606. Mild cold exposure modulates fibroblast growth factor 21 (FGF21) diurnal rhythm in humans: relationship between FGF21 levels, lipolysis, and cold-induced …
  607. Acute hyperenergetic, high-fat feeding increases circulating FGF21, LECT2, and fetuin-A in healthy men
  608. Single ingestion of soy β-conglycinin induces increased postprandial circulating FGF21 levels exerting beneficial health effects
  609. High plasma FGF21 levels predicts major cardiovascular events in patients treated with atorvastatin (from the Treating to New Targets [TNT] Study)
  610. Negative correlation between cerebrospinal fluid FGF21 levels and BDI scores in male Chinese subjects
  611. Long-acting hypoglycemic effects of PEGylated FGF21 and insulin glargine in mice with type 1 diabetes
  612. Heme-regulated eIF2α kinase modulates hepatic FGF21 and is activated by PPARβ/δ deficiency
  613. Contribution of serum FGF21 level to the identification of left ventricular systolic dysfunction and cardiac death
  614. Delayed recanalization at 3 days after permanent MCAO attenuates neuronal apoptosis through FGF21/FGFR1/PI3K/Caspase-3 pathway in rats
  615. High-fat diet and FGF21 cooperatively promote aerobic thermogenesis in mtDNA mutator mice
  616. … scoparia extract attenuates non-alcoholic fatty liver disease in diet-induced obesity mice by enhancing hepatic insulin and AMPK signaling independently of FGF21 …
  617. KLF15‐activating Twist2 ameliorated hepatic steatosis by inhibiting inflammation and improving mitochondrial dysfunction via NF‐κB‐FGF21 or SREBP1c‐FGF21 …
  618. Mutual promotion of FGF21 and PPARγ attenuates hypoxia-induced pulmonary hypertension
  619. The protective effect of FGF21 on diabetes-induced male germ cell apoptosis is associated with up-regulated testicular AKT and AMPK/Sirt1/PGC-1α signaling
  620. Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non‐alcoholic fatty liver disease by up‐regulating the FGF21/PGC‐1α pathway
  621. Circulating FGF19 and FGF21 surge in early infancy from infra-to supra-adult concentrations
  622. The suitability of FGF21 and FGF23 as new biomarkers in endometrial cancer patients
  623. Exercise ameliorates the FGF21–adiponectin axis impairment in diet-induced obese mice
  624. The effect of eight weeks high intensity interval training (HIIT) on serum amounts of FGF21 and irisin in sedentary obese women
  625. Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: The role of the PPARα-FGF21 axis
  626. Elevated FGF21 leads to attenuated postnatal linear growth in preterm infants through GH resistance in chondrocytes
  627. Roux-en-Y gastric bypass surgery has unique effects on postprandial FGF21 but not FGF19 secretion
  628. Adiponectin—a mediator of specific metabolic actions of FGF21
  629. FGF21 increases cholesterol efflux by upregulating ABCA1 through the ERK1/2–PPARγ–LXRα pathway in THP1 macrophage-derived foam cells
  630. Cord blood FGF21 in gestational diabetes and its relationship with postnatal growth
  631. Alternate-day fasting alleviates diabetes-induced glycolipid metabolism disorders: roles of FGF21 and bile acids
  632. Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice
  633. The FGF21 response to fructose predicts metabolic health and persists after bariatric surgery in obese humans
  634. Recruitment of histone methyltransferase G9a mediates transcriptional repression of FGF21 gene by E4BP4 protein
  635. Hepatic FGF21 production is increased in late pregnancy in the mouse
  636. Brown adipose tissue and browning agents: irisin and FGF21 in the development of obesity in children and adolescents
  637. REV-ERBα regulates FGF21 expression in the liver via hepatic nuclear factor 6
  638. Pemafibrate prevents retinal pathological neovascularization by increasing FGF21 level in a murine oxygen-induced retinopathy model
  639. Inhibition of the ox-LDL-induced pyroptosis by FGF21 of human umbilical vein endothelial cells through the TET2-UQCRC1-ROS pathway
  640. Fibroblast growth factor 21 (FGF21) protects against high fat diet induced inflammation and islet hyperplasia in pancreas
  641. Bone marrow mesenchymal stem cells: fat on and blast off by FGF21
  642. FGF21 protects human umbilical vein endothelial cells against high glucose-induced apoptosis via PI3K/Akt/Fox3a signaling pathway
  643. Suppression of Nrf2 attenuates adipogenesis and decreases FGF21 expression through PPAR gamma in 3T3-L1 cells
  644. HDAC3 inhibition in diabetic mice may activate Nrf2 preventing diabetes-induced liver damage and FGF21 synthesis and secretion leading to aortic protection
  645. … intake associations with fasting glucose and insulin concentrations are not modified by selected genetic variants in a ChREBP-FGF21 pathway: a meta …
  646. Serum FGF21 and RBP4 levels in patients with chronic hepatitis C
  647. Pharmacological efficacy of FGF21 analogue, liraglutide and insulin glargine in treatment of type 2 diabetes
  648. FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in …
  649. The effects of high intensity interval training on serum levels of FGF21 and insulin resistance in obese men
  650. Fibroblast growth factor 21 (FGF21) inhibits macrophage-mediated inflammation by activating Nrf2 and suppressing the NF-κB signaling pathway
  651. FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway
  652. Novel sandwich immunoassays for the measurement of total and active FGF21
  653. Increased leptin, decreased adiponectin and FGF21 concentrations in adolescent offspring of women with gestational diabetes
  654. Time‐restricted feeding alleviates cardiac dysfunction induced by simulated microgravity via restoring cardiac FGF21 signaling
  655. Valproic acid and other HDAC inhibitors upregulate FGF21 gene expression and promote process elongation in glia by inhibiting HDAC2 and 3
  656. Changes in plasma concentrations and mRNA expression of hepatokines fetuin A, fetuin B and FGF21 in physiological pregnancy and gestational diabetes …
  657. FGF21 reverses hepatic steatosis, increases energy expenditure and improves insulin sensitivity in diet-induced obese mice
  658. FGF21 is associated with metabolic effects and treatment response in depressed bipolar II disorder patients treated with valproate
  659. High FGF21 levels are associated with altered bone homeostasis in HIV-1-infected patients
  660. Exercise increases serum fibroblast growth factor 21 (FGF21) levels
  661. The cell adhesion molecule L1 regulates the expression of FGF21 and enhances neurite outgrowth
  662. Age‐related bone loss is associated with FGF21 but not IGFBP1 in healthy adults
  663. Commentary: FGF21 holds promises for treating obesity-related insulin resistance and hepatosteatosis
  664. A new FGF21 analog for the treatment of fatty liver disease
  665. Hepatic-specific PPARα-FGF21 action in NAFLD
  666. Effect of circulating glucagon and free fatty acids on hepatic FGF21 production in dairy cows
  667. Fibroblast growth factor 21 (FGF21) ameliorates collagen-induced arthritis through modulating oxidative stress and suppressing nuclear factor-kappa B pathway
  668. FGF21 protects against aggravated blood-brain barrier disruption after ischemic focal stroke in diabetic db/db male mice via cerebrovascular PPARγ activation
  669. Upregulation of rat liver PPARα‐FGF21 signaling by a docosahexaenoic acid and thyroid hormone combined protocol
  670. Optimization and characterization of a novel FGF21 mutant
  671. Interaction of glucocorticoids with FXR/FGF19/FGF21-mediated ileum-liver crosstalk
  672. Factors associated with cognitive impairment in elderly versus nonelderly patients with metabolic syndrome: the different roles of FGF21
  673. AKR-001, an Fc-FGF21 analog, showed sustained pharmacodynamic effects on insulin sensitivity and lipid metabolism in type 2 diabetes patients
  674. High-efficiency expression and secretion of human FGF21 in Bacillus subtilis by intercalation of a mini-cistron cassette and combinatorial optimization of cell …
  675. Fibroblast growth factor 21 (FGF21) inhibits chondrocyte function and growth hormone action directly at the growth plate
  676. Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet
  677. Therapeutic effect of dichloroacetate against atherosclerosis via hepatic FGF21 induction mediated by acute AMPK activation
  678. Activation of GR but not PXR by dexamethasone attenuated acetaminophen hepatotoxicities via FGF21 induction
  679. Diminished diet-induced hyperglycemia and dyslipidemia and enhanced expression of PPARa and FGF21 in mice with hepatic ablation of brain-derived …
  680. Protein intake and amino acid supplementation regulate exercise recovery and performance through the modulation of mTOR, AMPK, FGF21, and immunity
  681. … of circulating exosomes derived from normal-weight and obese women on gluconeogenesis, glycogenesis, lipogenesis and secretion of FGF21 and fetuin A …
  682. Hepatic c-Jun regulates glucose metabolism via FGF21 and modulates body temperature through the neural signals
  683. SIRT1 mediates effects of FGF21 to ameliorate cisplatin-induced acute kidney injury
  684. Alcohol ingestion induces pancreatic islet dysfunction and apoptosis via mediation of FGF21 resistance
  685. Alterations in Hepatic FGF21, Co-Regulated Genes, and Upstream Metabolic Genes in Response to Nutrition, Ketosis and Inflammation in Peripartal Holstein …
  686. FGF21 in ataxia patients with spinocerebellar atrophy and mitochondrial disease
  687. Glyco-engineered long acting FGF21 variant with optimal pharmaceutical and pharmacokinetic properties to enable weekly to twice monthly subcutaneous …
  688. Activation of AK005401 aggravates acute ischemia/reperfusion mediated hippocampal injury by directly targeting YY1/FGF21
  689. Recombinant Lactococcus lactis NZ3900 expressing bioactive human FGF21 reduced body weight of Db/Db mice through the activity of brown adipose tissue
  690. Weight loss and concomitant adipose autophagy in methionine-restricted obese mice is not dependent on adiponectin or FGF21
  691. Whole transcriptome analysis and validation of metabolic pathways in subcutaneous adipose tissues during FGF21-induced weight loss in non-human …
  692. The sum of all browning in FGF21 therapeutics
  693. Sterol 12α-hydroxylase aggravates dyslipidemia by activating the ceramide/mTORC1/SREBP-1C pathway via FGF21 and FGF15
  694. Activating transcription factor 4-dependent induction of FGF21 during amino acid deprivation
  695. Cardiac FGF21 synthesis and release: an autocrine loop for boosting up antioxidant defenses in failing hearts
  696. Sex dimorphism in the FGF21 gene expression in liver and adipose tissues is dependent on the metabolic condition
  697. Cardiac myocyte KLF5 regulates body weight via alteration of cardiac FGF21
  698. TGF-β2, EGF, and FGF21 growth factors present in breast milk promote mesenteric lymph node lymphocytes maturation in suckling rats
  699. FGF21 decreases food intake and body weight in obese Göttingen minipigs
  700. Glucagon-dependent suppression of mTORC1 is associated with upregulation of hepatic FGF21 mRNA translation
  701. Ampelopsin improves insulin resistance by activating PPARγ and subsequently up-regulating FGF21-AMPK signaling pathway
  702. FGF21 exerts comparable pharmacological efficacy with Adalimumab in ameliorating collagen-induced rheumatoid arthritis by regulating systematic inflammatory …
  703. Srebp-1c/FGF21/Pgc-1α axis regulated by leptin signaling in adipocytes—possible mechanism of caloric restriction-associated metabolic remodeling of white adipose …
  704. Integrated Regulation of Hepatic Metabolism by Fibroblast Growth Factor 21 (FGF21) in Vivo
  705. Development of a long acting FGF21 analogue-albumin fusion protein and its anti-diabetic effects
  706. FGF21 protects against ox-LDL induced apoptosis through suppressing CHOP expression in THP1 macrophage derived foam cells
  707. FGF21 and glycemic control in patients with T1D
  708. FGF21 mediates the associations between exercise, ageing and glucose regulation
  709. The effect of two concurrent exercise modalities on serum concentrations of FGF21, irisin, follistatin, and myostatin in men with type 2 diabetes mellitus
  710. Insulin sensitizes FGF21 in glucose and lipid metabolisms via activating common AKT pathway
  711. Alteration in serum concentrations of FGF19, FGF21, and FGF23 in patients with urothelial carcinoma
  712. Reduced oxidative stress and enhanced FGF21 formation in livers of endurance-exercised rats with diet-induced NASH
  713. Alterations in 3-hydroxyisobutyrate and FGF21 metabolism are associated with protein ingestion–induced insulin resistance
  714. The effect of hydration status on plasma FGF21 concentrations in humans: A subanalysis of a randomised crossover trial
  715. FGF21 is dispensable for hypothermia induced by fasting in mice
  716. Role of PPAR in the control of torpor through FGF21-NPY pathway: from circadian clock to seasonal change in mammals
  717. Whey protein isolate inhibits hepatic FGF21 production, which precedes weight gain, hyperinsulinemia and hyperglycemia in mice fed a high-fat diet
  718. Metformin promotes cholesterol efflux in macrophages by up-regulating FGF21 expression: a novel anti-atherosclerotic mechanism
  719. Effects of central FGF21 infusion on the hypothalamus–pituitary–thyroid axis and energy metabolism in rats
  720. Fasting induces FGF21 in humans
  721. The metabolic hormone FGF21 is associated with endothelial dysfunction in hemodialysis patients
  722. Expression and purification of FGF21 in Pichia pastoris and its effect on fibroblast-cell migration
  723. Ethyl acetate extract of sappanwood alleviates experimental atherosclerosis in rats through changes in FGF21 and SREBP-2 expression
  724. Hypocaloric diet prevents the decrease in FGF21 elicited by high phosphorus intake
  725. Gene expression profiling reveals that PXR activation inhibits hepatic PPARα activity and decreases FGF21 secretion in male C57BL6/J mice
  726. … of a new HRI activator as a new strategy to improve high‐fat‐diet‐induced glucose intolerance, hepatic steatosis, and hypertriglyceridaemia through FGF21
  727. Metabolic hormone FGF21 is induced in ground squirrels during hibernation but its overexpression is not sufficient to cause torpor
  728. FGF21 improves the adipocyte dysfunction related to seipin deficiency
  729. Tissue-specific actions of the metabolic hormones FGF15/19 and FGF21
  730. FGF21 inhibitor suppresses the proliferation and migration of human umbilical vein endothelial cells through the eNOS/PI3K/AKT pathway
  731. Fasting-induced FGF21 is repressed by LXR activation via recruitment of an HDAC3 corepressor complex in mice
  732. Ileal transposition surgery decreases fat mass and improves glucose metabolism in diabetic GK rats: possible involvement of FGF21
  733. Fibroblast growth factor 21 (FGF21) in human cerebrospinal fluid: relationship with plasma FGF21 and body adiposity
  734. Changes in FGF21 serum concentrations and liver mRNA expression in an experimental model of complete lipodystrophy and insulin-resistant diabetes
  735. Moderate-intensity continuous training improves FGF21 and KLB expression in obese mice
  736. Hepatic FGF21 expression is repressed after simvastatin treatment in mice
  737. High serum levels of FGF21 are decreased in bipolar mania patients during psychotropic medication treatment and are associated with increased metabolism …
  738. Sustained release of a GLP-1 and FGF21 dual agonist from an injectable depot protects mice from obesity and hyperglycemia
  739. Photoperiodic regulation of FGF21 production in the Siberian hamster
  740. Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury
  741. Mechanism for the effects of FGF21
  742. Hepatic STAMP2 mediates recombinant FGF21‐induced improvement of hepatic iron overload in nonalcoholic fatty liver disease
  743. Genetic fusion of human FGF21 to a synthetic polypeptide improves pharmacokinetics and pharmacodynamics in a mouse model of obesity
  744. LPS infusion suppresses serum FGF21 levels in healthy adult volunteers
  745. Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster
  746. Expression and pharmacological evaluation of fusion protein FGF21-L-Fc
  747. Liver GCN2 controls hepatic FGF21 secretion and modulates whole body postprandial oxidation profile under a low-protein diet
  748. DEPP/DEPP1/C10ORF10 regulates hepatic glucose and fat metabolism partly via ROS‐induced FGF21
  749. Astragalus polysaccharides affect insulin resistance by regulating the hepatic SIRT1-PGC-1α/PPARα-FGF21 signaling pathway in male Sprague Dawley rats …
  750. Effects of EPA and lipoic acid supplementation on circulating FGF21 and the fatty acid profile in overweight/obese women following a hypocaloric diet
  751. Erratum. Serum FGF21 Levels Are Increased in Obesity and Are Independently Associated With the Metabolic Syndrome in Humans. Diabetes 2008; 57: 1246–1253
  752. Parsing the potential neuroendocrine actions of FGF21 in primates
  753. Pegbelfermin (BMS‐986036), PEGylated FGF21, in patients with obesity and type 2 diabetes: results from a randomized phase 2 study
  754. FGF21 mediates the protective effect of fenofibrate against acetaminophen-induced hepatotoxicity via activating autophagy in mice
  755. Fibroblast growth factor-21 (FGF21) regulates low-density lipoprotein receptor (LDLR) levels in cells via the E3-ubiquitin ligase Mylip/Idol and the Canopy2 …
  756. PF-05231023, a long-acting FGF21 analogue, decreases body weight by reduction of food intake in non-human primates
  757. Intestinal serine protease inhibition increases FGF21 and improves metabolism in obese mice
  758. Digenic variants in the FGF21 signaling pathway associated with severe insulin resistance and pseudoacromegaly
  759. Cholesterol metabolism altered and FGF21 levels high after pediatric liver transplantation despite normal serum lipids
  760. … of Klothoβ (KLB) and fibroblast growth factor receptor-1 (FGFR1) in living cells reveal the fibroblast growth factor-21 (FGF21)-induced receptor complex
  761. Enhanced expression and distinctive characterization of a long-acting FGF21 and its potential to alleviate nonalcoholic steatohepatitis
  762. Restoration of leptin responsiveness in diet‐induced obese mice using an optimized leptin analog in combination with exendin‐4 or FGF21
  763. The Influence of Hypertensive Therapies on Circulating Factors: Clinical Implications for SCFAs, FGF21, TNFSF14 and TNF-α
  764. Successful glycemic control decreases the elevated serum FGF21 level without affecting normal serum GDF15 levels in a patient with mitochondrial diabetes
  765. FGF21 knockout mice generated using CRISPR/Cas9 reveal genetic alterations that may affect hair growth
  766. Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in …
  767. Two novel intronic polymorphisms of bovine FGF21 gene are associated with body weight at 18 months in Chinese cattle
  768. Increased HO‐1 levels ameliorate fatty liver development through a reduction of heme and recruitment of FGF21
  769. An Exome-Chip Association Analysis in Chinese Subjects Reveals a Functional Missense Variant of GCKR That Regulates FGF21 Levels
  770. Characterization and quantification of an fc-FGF21 fusion protein in rat serum using immunoaffinity LC-MS
  771. Changes in selected biochemical parameters (including FGF21) during subclinical and clinical ketosis in dairy cows
  772. Large-scale expression, purification, and glucose uptake activity of recombinant human FGF21 in Escherichia coli
  773. Effects of beta-conglycinin intake on circulating FGF21 levels and brown adipose tissue activity in Japanese young men: a single intake study and a …
  774. … okamurae extract ameliorates the hyperglycemia and body weight gain of db/db mice through regulation of the PI3K/Akt pathway and thermogenic factors by FGF21
  775. Baseline circulating FGF21 concentrations and increase after fenofibrate treatment predict more rapid glycemic progression in type 2 diabetes: results from the FIELD …
  776. Fibroblast Growth Factor 21 (FGF21) and Glucagon-Like Peptide 1 Contribute to Diabetes Resistance in Glucagon Receptor–Deficient Mice
  777. Modulation of the systemic immune response in suckling rats by breast milk TGF-β2, EGF and FGF21 supplementation
  778. Uric acid induced hepatocytes lipid accumulation through regulation of miR-149-5p/FGF21 axis
  779. The sweetest thing: regulation of macronutrient preference by FGF21
  780. Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation
  781. FGF21 regulates melanogenesis in alpaca melanocytes via ERK1/2-mediated MITF downregulation
  782. Genetic variants flanking the FGF21 gene were associated with renal function in Chinese patients with type 2 diabetes
  783. FGF21 analogue shows promise in the clinic
  784. Fibroblast growth factor 21 (FGF21) and bone: is there a relationship in humans?
  785. The moderate essential amino acid restriction entailed by low-protein vegan diets may promote vascular health by stimulating FGF21 secretion
  786. Autofluorescence imaging of living pancreatic islets reveals fibroblast growth factor-21 (FGF21)-induced metabolism
  787. Role of fibroblast growth factor 21 (FGF21) in undernutrition-related attenuation of growth in mice
  788. Pharmacologic inhibition of serotonin htr2b ameliorates hyperglycemia and the altered expression of hepatic FGF21, Sdf2l1, and htr2a in db/db mice and …
  789. FGF21 is associated with Acanthosis nigricans in obese patients
  790. The role of fibroblast growth factor 21 (FGF21) on energy balance, glucose and lipid metabolism
  791. Lower cerebrospinal fluid/plasma fibroblast growth factor 21 (FGF21) ratios and placental FGF21 production in gestational diabetes
  792. Berberine-induced activation of AMPK increases hepatic FGF21 expression via NUR77
  793. Agonistic β-Klotho antibody mimics fibroblast growth factor 21 (FGF21) functions
  794. … protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21)
  795. FGF21 regulates T-cell development in the neonatal and juvenile thymus
  796. miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction
  797. Differentiated embryo chondrocyte 1 (DEC1) is a novel negative regulator of hepatic fibroblast growth factor 21 (FGF21) in aging mice
  798. Role of adipokines FGF21, leptin and adiponectin in self-concept of youths with obesity
  799. Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by inducing …
  800. Klotho, FGF21 and FGF23: novel pathways to musculoskeletal health?
  801. Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids
  802. Highly selective and sensitive measurement of active forms of FGF21 using novel immunocapture enrichment with LC–MS/MS
  803. Fasting insulin and alanine amino transferase, but not FGF21, were independent parameters related with irisin increment after intensive aerobic exercising
  804. Hepatic stearoyl CoA desaturase 1 deficiency increases glucose uptake in adipose tissue partially through the PGC-1α–FGF21 axis in mice
  805. Associations between FGF21, osteonectin and bone turnover markers in type 2 diabetic patients with albuminuria
  806. A tryptophan hydroxylase inhibitor decreases hepatic FGF21 expression and circulating FGF21 in mice fed a high-fat diet
  807. FGF21 and its Relationship with Inflammatory and Metabolic Parameters in HIV Patients after Antiretroviral Treatment
  808. Chronic activation of PPARα with fenofibrate reduces autophagic proteins in the liver of mice independent of FGF21
  809. Hepatic FGF21 mediates tissue tolerance during bacterial inflammation by preserving cardiac function
  810. Elevated Fibroblast growth factor 21 (FGF21) in obese, insulin resistant states is normalised by the synthetic retinoid Fenretinide in mice
  811. Therapeutic approaches to Alzheimer’s type of dementia: a focus on FGF21 mediated neuroprotection
  812. Mediterranean Tomato‐Based Sofrito Sauce Improves Fibroblast Growth Factor 21 (FGF21) Signaling in White Adipose Tissue of Obese ZUCKER Rats
  813. In pursuit of a biomarker of weight gain susceptibility—is FGF21 a candidate?
  814. Metabolic responses to 24-hour fasting and mild cold exposure in overweight individuals are correlated and accompanied by changes in FGF21 concentration
  815. Effects of central fibroblast growth factor 21 (FGF21) in energy balance.
  816. Changes in liver gene expression and plasma concentration of Rbp4, Fetuin-A, and FGF21 in sprague-dawley rats subjected to different dietary interventions …
  817. α1-Adrenergic receptor downregulates hepatic FGF21 production and circulating FGF21 levels in mice
  818. FGF21 inhibits apolipoprotein (a) expression in HepG2 cells via the FGFR1-ERK1/2-Elk-1 pathway
  819. FGF21-protection against fructose-induced lipid accretion and oxidative stress is influenced by maternal nutrition in male progeny
  820. Circulating fibroblast growth factor 21 (FGF21) as diagnostic and prognostic biomarker in renal cancer
  821. Pulse wave velocity is associated with increased plasma oxLDL in ageing but not with FGF21 and habitual exercise
  822. Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. I. Effects on signaling and indices of insulin action
  823. Mapping the response of human fibroblast growth factor 21 (FGF21) promoter to serum availability and lipoic acid in HepG2 hepatoma cells
  824. FGF21 drives a shift in adipokine tone to restore metabolic health
  825. … cyanidin-3-glucoside attenuates high-fat-diet–induced body-weight gain and impairment of glucose tolerance in mice via effects on the hepatic hormone FGF21
  826. Therapeutic potential of FGF21 in diabetes
  827. A combined docosahexaenoic acid–thyroid hormone protocol upregulates rat liver β-Klotho expression and downstream components of FGF21 signaling as a …
  828. Maresin 1 regulates hepatic FGF21 in diet‐induced obese mice and in cultured hepatocytes
  829. Fibroblast growth factor 21 (FGF21) in children and adolescents with chronic kidney disease
  830. Balanced coagonist of GLP-1 and glucagon receptors corrects dyslipidemia by improving FGF21 sensitivity in hamster model
  831. The effect of vigorous aerobic exercise on serum levels of SIRT1, FGF21 and Fetuin A in women with type Ⅱ diabetes
  832. The swinging pendulum of biomarkers in mitochondrial disease: the role of FGF21
  833. Roles of FGF21 and irisin in obesity-related diabetes and pancreatic diseases
  834. The effect of high intensity interval training on serum levels of FGF21, insulin resistance and lipid profile in sedentary obese women
  835. Fibroblast Growth Factor 21 (FGF21) Gene Expression Is Elevated in the Liver of Mice Fed a High-Carbohydrate Liquid Diet and Attenuated by a Lipid Emulsion but Is …
  836. TCF4/β‑catenin complex is directly upstream of FGF21 in mouse stomach cancer cells
  837. Therapeutic role of fibroblast growth factor 21 (FGF21) in the amelioration of chronic diseases
  838. Predictive value of combined serum FGF21 and free t3 for survival in septic patients
  839. NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1
  840. Physiological and transcriptome analyses of transgenic FGF21 immature Rice seeds
  841. A common allele in FGF21 associated with preference for sugar consumption lowers body fat in the lower body and increases blood pressure
  842. Lipodystrophy HIV-related and FGF21: A new marker to follow the progression of lipodystrophy?
  843. Circulating CTRP1 levels in type 2 diabetes and their association with FGF21
  844. Plasma FGF21 concentrations, adipose fibroblast growth factor receptor-1 and β-klotho expression decrease with fasting in northern elephant seals
  845. Serum FGF21 in boys with idiopathic short stature: relationship to lipid profile, onset of puberty and growth
  846. Fibroblast growth factor-21 (FGF21) administration to early-lactating dairy cows. II. Pharmacokinetics, whole-animal performance, and lipid metabolism
  847. TRIB3 limits FGF21 induction during in vitro and in vivo nutrient deficiencies by inhibiting C/EBP–ATF response elements in the FGF21 promoter
  848. Thyroid hormone-induced expression of the hepatic scaffold proteins Sestrin2, β-Klotho, and FRS2α in relation to FGF21-AMPK signaling
  849. Cloning of goat FGF21 gene and its expression pattern in intramuscular adipocyte.
  850. Corrigendum to “ATF4-and CHOP-Dependent Induction of FGF21 through Endoplasmic Reticulum Stress”
  851. Is FGF23 or FGF21 a promising biomarker to indicate the aging process in COPD?
  852. FGF21 activation-mediated islet autophagy in Type 2 diabetes with pharmacotherapeutic potential
  853. Pharmacologic stimulation of central GLP-1 receptors has opposite effects on the alterations of plasma FGF21 levels induced by feeding and fasting
  854. TM-25659-induced activation of FGF21 level decreases insulin resistance and inflammation in skeletal muscle via GCN2 pathways
  855. FGF21 levels in pheochromocytoma/functional paraganglioma
  856. Moxibustion-simulating bipolar radiofrequency suppresses weight gain and induces adipose tissue browning via activation of UCP1 and FGF21 in a mouse …
  857. Serum levels of FGF21 and prediction of cardiovascular events
  858. FGF21, not GCN2, influences bone morphology due to dietary protein restrictions
  859. The good, the bad, and the unknown: Fructose and FGF21
  860. Relationship between Circulating FGF21 Concentrations and the Severity of Coronary Artery Damage in Subjects with Cardiovascular Disease
  861. Practical prospects for boosting hepatic production of the “pro-longevity” hormone FGF21
  862. Oral bezafibrate induces daily torpor and FGF21 in mice in a PPAR alpha dependent manner
  863. MS-275 induces hepatic FGF21 expression via H3K18ac-mediated CREBH signal
  864. Are you thirsty? FGF21 might be involved in that too
  865. Are Circulating FGF21 and NT-proBNP promising novel biomarkers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome?
  866. FGF21—the cause of having a’sweet tooth’?
  867. Higher increase degree of FGF21 post long-term interdisciplinary weight loss therapy preserves the free fat mass and rest metabolic rate in adolescents with …
  868. The Metabolic Effects of FGF21: From Physiology to Pharmacology
  869. FGF21 ACEs hypertension
  870. Study on the kidney impairment and expressions of FGF21 from a rat model of vascular calcification
  871. Plasma FGF21 levels in rats are dependent on dietary proteins but not on dietary carbohydrates or fats
  872. Mice lacking neutral amino acid transporter B⁰AT1 (Slc6a19) have elevated levels of FGF21 and GLP-1 and improved glycaemic control
  873. IGFBP1—hepatokine and target for FGF21-mediated bone loss
  874. Levels of Fibroblast Growth Factor 21 (FGF21) in serum as diagnostic biomarker in patients with breast cancer
  875. Role of fibroblast growth factor 21 (FGF21) in the regulation of statural growth
  876. 1060-P: The Effect of FGF21/GLP-1 Fusion Protein on Glucose and Lipid Metabolism Using Diabetic Mice Models
  877. Comment on serum FGF21 and RBP4 levels in patients with chronic hepatitis C
  878. The effect of 8 weeks of aerobic exercise on serum levels of FGF21, Apolipoprotein A-1 and LDL-C to HDL-C ratio in obese women
  879. Methionine Restriction Alleviates Aging-related Cognitive Dysfunction via Stimulating FGF21-driven Mitochondrial Biogenesis (P14-026-19)
  880. The Role of FGF21 in Pancreatic Islet Metabolism
  881. Capparis spinosa improves the high fat diet-induced non-alcoholic steatohepatitis in rats: the possible role of FGF21
  882. The Effect of Eight Weeks of High Intensity Interval Training (HIIT) on Serum Irisin, FGF21 and Glycemic Indices in Type 2 Diabetic Women
  883. Comment on “FGF21 Response to Critical Illness: Effect of Blood Glucose Control and Relation With Cellular Stress and Survival” by Thiessen SE, et al
  884. Potential role for FGF21 as a mediator of thyroid hormone effects on metabolic regulation
  885. Divergent Metabolic and Cardiovascular Effects of FGF21
  886. Increase in FGF21 stimulates browning markers in white adipose tissue in rats fed a low protein high carbohydrate diet during acute cold exposure
  887. Link between FGF21 and blood pressure
  888. FGF21 inhibits lipid accumulation and inflammation induced by palmitate in human hepatocytes via SIRT1 pathway
  889. Effects of ethinylestradiol-cyproterone acetate vs. pioglitazone-flutamide-metformin on plasma FGF21 levels in adolescent girls with androgen excess
  890. Therapeutic Potential of FGF21 in Alzheimer’s Disease
  891. Evaluation of a cell model expressing βKlotho for screening FGF21 analogues
  892. PEG-FGF21 variant improves hepatic steatosis in a mouse model of NASH as determined by quantitative water-fat MRI
  893. Association of the 3′ UTR polymorphism (rs11665896) in the FGF21 gene with metabolic status and nutrient intake in children with obesity
  894. FGF21 levels in patients with breast cancer
  895. FGF21 inhibits adiponectin secretion in human adipocytes
  896. Pancreatitis: a loss of FGF21 function disease with potential for correction
  897. Effects of eight-week resistance training on serum level of βKlotho and FGF21 in diabetic women with non-alcoholic fatty liver disease
  898. A tryptophan hydroxylase inhibitor increases hepatic FGF21 production and decreases hepatic gluconeogenesis independently of insulin in db/db mice
  899. Astaxanthin Attenuates Hepatic Damages and Mitochondrial Dysfunction in Nonalcoholic Fatty Liver Disease by Regulating the FGF21/PGC-1α Pathway
  900. Key role for FGF21 in GLP1-mediated weight loss
  901. Mechanisms of action of methionine restriction and fibroblast growth factor 21 (FGF21)
  902. OR01-3 microRNA-34a-mediated FGF21 resistance in the adipose tissue contributes to insulin resistance and hypoadiponectinemia in diet-induced obesity
  903. Hepatic FGF21 is Under the Regulation of the Canonical Wnt Signaling Pathway
  904. The Role of FGF21 in Regulating Lipid and Glucose Metabolism
  905. Identification of a crucial amino acid responsible for the loss of specifying FGFR1–KLB affinity of the iodinated FGF21
  906. The Potential of Hibiscus sabdariffa Linn. for Treatment of Obesity: Focus on FGF21 in Liver and Adipose Tissue
  907. The Effect of Resistance Training with High and Moderate Intensities on Lipid Profile, Glycemic Index and FGF21 in Type 2 Diabetic Patients
  908. 370-OR: Hepatic FGF21 Expression Is Under the Regulation of the Canonical Wnt Signaling Pathway
  909. FGF21 determined angiogenic phenotypes in pulmonary endothelial cells
  910. P612 Involvement of the cardiomyokine FGF21 in protection against oxidative stress damage in the heart.
  911. The role of hepatic FGF21 (Fibroblast Growth Factor 21) in the maintenance of metabolic homeostasis during metabolic stress
  912. FGF21 action on human adipose tissue compromised by reduced βKlotho and FGFR1 expression in type 2 diabetes mellitus
  913. FGF21 alleviates neuroinflammation following ischemic stroke by modulating the temporal and spatial dynamics of microglia/macrophages
  914. Defective autophagy causes a maladaptive cardiac phenotype to exercise that leads to premature death and FGF21‐mediated protection against obesity and insulin …
  915. Protective Role of FGF21 in Adverse Cardiac Remodeling After Myocardial Infarction
  916. Effect of EPO on PRDM16, FGF21 expression and STAT phosphorylation of brown adipose tissue in HFD mice
  917. SREBP-1c knockdown attenuated fatty degeneration in hepatic L02 cells and inhibited CCL2 and FGF21 protein expression
  918. Positive correlations between and prediction of FGF21, adiponectin, leptin and NPY concentrations in the cerebrospinal fluid of Chinese subjects using back …
  919. GW29-e1353 A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling via Promoting Brown Adipose Tissue-Derived FGF21
  920. Construction of FGF21 knockout mouse models by the CRISPR/Cas9 system.
  921. Lack of FGF21 accelerates NASH-HCC transition via up-regulation of hepatic SPHK1-S1P-HIPPO signaling in murine models
  922. DOCTORAL DISSERTATION Translational Aspects of FGF21
  923. FGF21 and its Relationship with Inflammatory and Metabolic Parameters in HIV Patients after Antiretroviral Treatment
  924. Cloning and Expression Analysis of FGF21 Gene in Ctenopharyngodon idellus
  925. Restoring FGF21 reverses pancreatitis.
  926. Mechanisms and dynamics of mitochondrial disease stress responses: special emphasis on FGF21
  927. Altered FGF21 response in alcohol induced “Acute-on-chronic liver injury”(ACLI) model
  928. Expression, purification and characterization of recombinant canine FGF21 in Escherichia coli
  929. Therapeutic potential of FGF21 in cardiorenal syndrome
  930. Dietary protein and age-dependent female fertility: FGF21 trumps mTORC1
  931. The effects of eight weeks of resistance training on serum levels of FGF21, LCAT and LDL-C to HDL-C ratio in obese women
  932. Role of FGF21 and GCN2 in mediating the metabolic response to dietary protein restriction
  933. FGF21 Coordinates Adiponectin to Mediate the Beneficial Effects of Low-Protein Diet on Primordial Follicle Reserve
  934. Fibroblast Growth Factor 21 (FGF21) creates sugar-specific taste aversion to fructose through action in the brain in mice
  935. Effect of FGF21 on short-term white adipocyte adiponectin secretion
  936. An investigation of acute exercise and FGF21.
  937. The Liver-Derived Endocrine Hormone FGF21 Alters Metabolism and Diurnal Behavior via the Nervous System
  938. FGF21 prevents high fat diet-induced pancreatic cancer in mice expressing oncogenic Kras
  939. Regulation of the organokines FGF21 and chemerin by diet: metabolic and molecular effects in liver and adipose tissue of obese human subjects
  940. P1499 FGF21 CORRELATES POSITIVELY WITH ARTERIOVENOUS FISTULA OCCLUSION IN HEMODIALYSIS PATIENTS
  941. STUDIES ON THE REGULATION OF FGF21 GENE EXPRESSION BY (R)-α-LIPOIC ACID: MECHANISTIC INSIGHT INTO THE LIPID LOWERING PROPERTIES OF A …
  942. A2A Receptor Activation Attenuates Hypertensive Cardiac Remodeling Via Promoting Brown Adipose Tissue-Derived FGF21
  943. A Polymorphism in the FGF21 Gene is a Novel Risk Variant for Metabolic-Associated Steatohepatitis
  944. Expression of FGF21 and receptors FGFR1, FGFR2 in the first hair follicle growth cycle of mice.
  945. Association of FGF19, FGF21 and FGF23 with carbohydrate metabolism parameters and insulin resistance in patients with chronic kidney disease.
  946. FGF21 mediates corticosteroid-related bone mass loss through PPAR-
  947. O29: Régulation circadienne et nutritionnelle de FGF21 par PPARalpha
  948. Altered GDF15 and FGF21 Levels in Response to Strenuous Exercise: A Study in Marathon Runners
  949. Elevated FGF21 during insufficient sleep in active but not sedentary volunteers
  950. The secret life of FGF21
  951. FGF21 mediates the anti-depressant effects of exercise by coordinating the crosstalk between central and peripheral organs
  952. FGF21—central pathways of action unravelled
  953. Mistranslation drives alterations in protein levels and the effects of a synonymous variant at the FGF21 locus
  954. Factor-Associated Risk Factors of Mild Cognitive Impairment in Thalassemia Patients: Probable Role of FGF21
  955. Lack of FGF21 promotes NASH-HCC transition via exosome-mediated carcinogenetic signaling
  956. Fibroblast growth factor 21 (FGF21) in hyper-and hypothyroidism, association with metabolic disturbances
  957. FGF21: un lien entre reproduction et métabolisme
  958. FGF21 Expresses in Diabetic Hearts and Protects from Palmitate- and Diabetes-Induced Cardiac Cell Death In Vitro and In Vivo Via Erk1/2-Dependent P38 Mapk …
  959. FGF21 Prospects for Applications in Clinical Practice
  960. FGF21 restores photoreceptor function in type 1 diabetic mice
  961. FGF21: How sweet it is!
  962. mAb about FGF21
  963. Microglia-derived FGF21 as a modulator of astrocytic phenotype and cerebral ischemia injury
  964. Adipose and nonadipose effects of FGF21 delineated
  965. FGF21 as a Biomarker for Metabolic Stress in Heart Failure
  966. Effect of Moderate Aerobic Exercise on Serum Levels of FGF21 and Fetuin A in Women with Type 2 Diabetes
  967. The Physiology and Pharmacology of FGF21 in the Exocrine Pancreas
  968. The Consequences of LP Diet on Food Intake, Energy Expenditure and Hepatic and Hypothalamic FGF21 Are Reproduced by lLsine or Threonine Deficiency in Rats
  969. FGF21 action in the fat
  970. BIO89-100, a novel glycoPEGylated FGF21 Analog, Demonstrates Triglyceride Reduction and Broad Metabolic Effects in Spontaneously Diabetic Obese Cynomolgus …
  971. Correction for: Activation of AK005401 aggravates acute ischemia/reperfusion mediated hippocampal injury by directly targeting YY1/FGF21
  972. Ontogeny of FGF21 in the Human: Implications for Metabolic Health
  973. FGF21: A biomarker of neuromuscular diseases
  974. Regulation of glucose homeostasis by FGF21
  975. Comparison of Resistance, Aerobic and Combined Trainings Effects on the FGF21 Serum Levels in Active Elderly Men
  976. Regulation of Glucose Homeostasis by FGF21
  977. P3478 Glucose-dependent insulinotropic peptide is essential for maintenance of cardiac lipid metabolism via FGF21-dependent pathway
  978. Lack of FGF21 accelerates the Th17-IL-17 axis-mediated transition from nonalcoholic steatohepatitis to hepatocellular carcinoma
  979. The therapeutic effects of FGF21 on diabetic nephropathy are realized by augmenting autophagy via AMPK/mTOR signaling pathway
  980. FGF21 in acute and chronic alcohol consumption
  981. Fibroblast growth factor 21 (FGF21), free fatty acid (FFA), high sensitivity C-reactive protein (hsCRP) and homeostasis model assessment of insulin resistance (HOMA …
  982. FGF21 gets the juices flowing
  983. FGF21 prevented diabetic renal fibrosis
  984. Effect and mechanism of FGF21 on astrocyte damage induced by Aβ25-35
  985. FGF21 influences a’sweet tooth’in mice
  986. FGF21: starvation hormone to a clinical drug?
  987. 282-LB: Dysregulated FGF21 Links Hepatic Insulin Resistance to Dysfunctional BAT
  988. FGF21 Attenuates Neurodegeneration though Reducing Neuroinflammation and Oxidant-stress
  989. Mechanism of metabolic surgery mediated FGF21 in improving insulin resistance
  990. Glucagon Regulates Energy Balance via FGF21 Signaling in the Brain
  991. Pharmacological effects of recombinant FGF21 in ovariectomized mice C57Bl/6J
  992. The role of FGF21 in regulating energy homeostasis
  993. PPARα is a Key regulator of Hepatic FGF21 PPAR is a Key regulator of Hepatic FGF21
  994. Correlations between serum FGF21 and IRISIN levels and nutritional, biochemical, and anthropometric parameters in non-alcoholic fatty liver disease
  995. Expression of recombinant h-FGF21 in periplasmic space of Escherichia coli
  996. P rocess development of a FGF21 protein–antibody conjugate
  997. Regulation of FGF21 Gene Expression by Nutritional Signals and Physical Activity in vivo and in vitro
  998. Low protein/low methionine/high carbohydrate diets induce hyperphagia, increase energy expenditure and FGF21, but modestly affect adiposity in female BalbC mice.
  999. The physiology and pharmacology of the fasting-induced hormone, FGF21
  1000. FGF21 improves glucose homeostasis in diabetes-prone NZO mice
  1001. FGF21 in NASH and Liver Fibrosis
  1002. Going hedonic-the role of FGF21 in the preference for sweet and alcohol
  1003. FGF21 prevented diabetic renal fibrosis
  1004. Mesenchymal Stem Cells Overexpressing FGF21 Improve Functional Recovery After Traumatic Brain Injury
  1005. BIO89-100, a Novel Glycopegylated FGF21 Analogue, Demonstrates Robust Reduction in Serum Lipids and Long Half-life in a Phase 1 Randomized …
  1006. Serum FGF21 Levels in Obese Korean Children and Adolescents (J Obes Metab Syndr 2017; 26: 204–9)
  1007. Characterization of changes in temporal concentrations of fibroblast growth factor 21 (FGF21) before and after parturition in multiparous beef cows
  1008. Metabolic Stress Hormone FGF21: From Physiology to Pharmacology
  1009. Exercise, FGF21, and PGC-1: roles in hepatic metabolism
  1010. The role of FGF21 in the metabolic response to amino acid restriction
  1011. Hepatic FGF21 Expression Is Repressed after Simvastatin Treatment in Mice
  1012. Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake
  1013. P27. The fasting hormone FGF21-an alternative therapy for Alzheimer’s disease?
  1014. Dietary Carbohydrates but Not Proteins Are the Main Nutritional Determinant of FGF21 Production in Mice
  1015. Synchronizing Metabolism, Physiology, and Behavior Through mTORC1 and FGF21
  1016. Dietary Protein Restriction and FGF21 Influence Bone Morphology
  1017. Translational Control of FGF21 mRNA Expression is Responsive to Nutritional Stress
  1018. Effect of FGF21 on TLR4/p38MAPK Signaling Pathway in Nonalcoholic Fatty Liver Diseases of Rats
  1019. Long-acting FGF21 inhibits retinal vascular leakage in vivo and in vitro model
  1020. Patent: Methods of Treating FGF21-Associated Disorders
  1021. 1957-P: Intermittent Ketogenic Diet Ameliorates Diet-Induced Obesity and Fatty Liver with Improved FGF21 Signaling
  1022. Abstract WMP81: FGF21 Reduces Post-Stroke Blood Brain Barrier Damage in Diabetic db/db Male Mice
  1023. FGF21 resistance in adipose tissues as a cause of insulin resistance?
  1024. The impact of FGF21 on cardiac and whole-body energy metabolism
  1025. Preface to special issue on ‘The hormone FGF21: a paramount actor of endocrine metabolic regulation, and even more’
  1026. Relationship of FGF21 Levels With Major Cardiovascular Events in Patients Treated With Atorvastatin (From the Treating to New Targets [TNT] Study)
  1027. The role of fibroblast growth factor 21 (FGF21) in the regulation and correction of carbohydrate and lipid metabolism
  1028. Lactobacillus helveticus-MIKI-020 enhances hepatic FGF21 expression and decreases the core body temperature during sleep in mice
  1029. FGF21 inhibits omentin expression in adipocytes
  1030. The Protection of FGF21 on Chronic-Binge Alcohol-Induced Liver Injury
  1031. Low Protein/low Methionine/high Carbohydrate Diets Induce Hyperphagia, Increase Energy Expenditure and FGF21, but Modestly Affect Adiposity in Female BalbC …
  1032. Oral fructose does not acutely affect circulating FGF21 in mice
  1033. Administration of FGF21 analogue ameliorates hyperglycemia in streptozotocin-induced diabetic mice
  1034. 233-LB: Spinal Cord Injury Inhibited-FGF21 Signaling Is Associated with Dysregulation of Metabolic Gene Expression in Mouse Liver and Adipose Tissue
  1035. KLB, Encoding the Co-receptor for FGF21, is Mutated in Congenital Hypogonadotropic Hypogonadism
  1036. Preparation of Prokaryotic Expression Construct of Human FGF21 cDNA and Its Recombinant Protein Expression
  1037. FGF21 Is Epigenetically Regulated by a Methyl Donor Rich Diet and a Transgenerational Model of IUGR.
  1038. Effects of eight-week resistance training on serum level of β Klotho and FGF21 in diabetic women with non-alcoholic fatty liver disease
  1039. Mitogenic response of human carcinoma cells to the liver-derived hormone FGF21
  1040. FGF21 promotes the growth and proliferation of melanoma cells through regulating intracellular fatty acid oxidation
  1041. Induction of FGF21 by CO/PERK/ATF4 Pathway Mediates Metabolic Homeostasis
  1042. Protection of FGF21 as well as metallothionein for high fat diet induced cardiomyocyte impairment.
  1043. Estimation of FGF21 Concentration in Prepubertal Children with Growth Hormone Deficiency before and after 6 Months of Growth Hormone Treatment
  1044. FGF21, irisin and other novel players in endocrine metabolic regulation
  1045. 523: Fibroblast Growth Factor 21 (FGF21) protein levels in the placenta of macrosomic infants
  1046. Cardiac Fibroblast-derived FGF21 is a Novel Therapeutic Target for Cardiac Pathological Remodeling
  1047. Expression of FGF21 and β-Klotho regulate hepatic fibrosis through NF-κB and JNK pathways
  1048. Serum FGF21 Levels in Obese Korean Children and Adolescents (J Obes Metab Syndr 2017; 26: 204-9)
  1049. Protein restriction induces FGF21-dependent mechanisms that are distinct from dietary restriction to protect mice from high-fat diet-induced obesity and glucose …
  1050. 1833-P: A Novel Genetic Modified and Pegylated FGF21 Analog for the Treatment of Nonalcoholic Steatohepatitis in Nonhuman Primates
  1051. Central resitin infusion impairs FGF21/FGFR1/β-Klotho hypothalamic expression and promotes peripheral FGF21 resistance: involvement of resistin/TLR4 signalling …
  1052. Serum levels of FGF21 are reduced and negatively correlated with adiponectin in children with Prader-Willi syndrome
  1053. Autophagy, FGF21 and glucagon during critical illness: interactions and therapeutic perspectives
  1054. The Effects of Obesity, Weight Loss, and Weight Gain on Thymic Expression of FGF21
  1055. FGF21 regulates circadian behavior and metabolism by acting on the nervous system
  1056. The Carbohydrate-and Alcohol Intakes Associated FGF21 Genotype, Change in Alcohol Consumption, and Weight Change
  1057. Association of serum FGF21 levels with clinical parameters in elder patients with type 2 diabetes.
  1058. Towards Examining FGF21 Secretion from Pancreatic Islets in a Microfluidic Device
  1059. High Casein Diet Differentially Alters FGF21 Levels in Plasma and Cardiac Tissue in Rats
  1060. Fructose ingestion acutely stimulates circulating FGF21 levels in humans
  1061. Effects of Hydroalcoholic Extract of Sargassum Oligocystum on Serum Concentration of SIRT1 and FGF21 in Streptozotocin Induced Diabetic Rat
  1062. P107: NLRP3 inflammasome activation in macrophages suppresses FGF21 production in hepatocytes
  1063. Potential role of FGF21 in the metabolic pathophysiology of an ovine model of polycystic ovary syndrome
  1064. Skeletal muscle mitochondrial uncoupling induces a metabolic rescue cycle involving FGF21 as a myokine
  1065. Hepatic regulation of VLDL receptor by PPARb/d and FGF21 modulates non-alcoholic fatty liver disease
  1066. 227-LB: Dietary Protein Restriction Induced–FGF21 Improves Metabolic Health during Aging
  1067. Association between Serum FGF21 levels and bone mineral density in healthy postmenopausal Korean women
  1068. Circulating FGF21 in humans is potently induced by short term overfeeding of carbohydrates
  1069. Research progress on glycolipid metabolism regulating of FGF19 and FGF21 in adipose tissue
  1070. Cord Blood FGF21 and Leptin as Candidate Biomarkers of Early Infant Linear Growth Velocity in a Low‐Income Country
  1071. Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin 2 resistant mouse models—-Association with liver and adipose tissue effects 3
  1072. THE EFFECT OF ONE SESSION OF ENDURANCE TRAINING ON SERUM LEVELS OF FGF21 AND INSULIN RESISTANCE IN SEDENTARY WOMEN
  1073. Nutritional regulation of the hepatokine FGF21 in the liver: interdependence of the transcription factors ChREBP and PPARα
  1074. Oral recombinant Lactococcus lactis NZ3900 expressing bioactive human FGF21 reduced body weight of DbDb mice through the activity of brown adipose tissue
  1075. SUN-253 FGF21 correlates positively with arteriovenous fistula occlusion in hemodialysis patients
  1076. MUSCLE-RELATED miRNAS AND ITS RELATIONSHIP WITH CIRCULATING GDF15 AND FGF21 LEVELS IN PATIENTS WITH CARDIAC CACHEXIA
  1077. Heme Oxygenase-PPARα Induction of FGF21 in Hepatocytes Recruits pAMPK/pAKT and Attenuates Insulin Resistance in Obese Mice
  1078. … Children and Adolescents Have Higher Bone Mineral Density Than Normal Weighted Controls but Lower than Metabolically Healthy Obeses: No Effect of FGF21 …
  1079. LY2405319, a analog of FGF21 ameliorates α-SMA production through inhibition of succinate-GPR91 pathway in mice
  1080. GW26-e1025 Fenofibrate Prevention of Diabetic Cardiomyopathy Is Mediated by FGF21 Via Sirt1-Dependent Autophagy Modulation
  1081. Pterostilbene inhibits palmitate-induced lipid deposition in L6 myotubes by modulating PLIN5/FGF21 pathway.
  1082. … ARTICLE by a Recently Elected Academy Member: Hepatic mTORC1 controls locomotor activity, body temperature, and lipid metabolism through FGF21
  1083. PO-163 Aerobic exercise activates myocardial FGF21/FGFR1/PI3K-AKT signaling pathway and inhibits cardiomyocyte apoptosis in post-myocardial infarction rats
  1084. Thyroid Hormone-Induced Expression of the Hepatic Scaffold Proteins Sestrin2, β-Klotho, and FRS2α in Relation to FGF21-AMPK Signaling
  1085. Impacts of prenatal FGF21 upregulation on the thermogenic gene expression in the white adipose tissues of male C57BL/6J mice at adult stages
  1086. Vildagliptin Attenuates Cardiac Hypertrophy and Improves Ventricular Efficiency Through FGF21 Expression in Pressure-overloaded Mouse Heart
  1087. 1811-P: Induction of Hepatic Steatosis by a Methionine Choline Deficient Diet Promotes FGF21-Induced Insulin Secretion Independent of Diabetes
  1088. Effect of a bout of acute cold water immersion on circulating FGF21, Irisin and T3 hormones in SCUBA divers
  1089. Decreased beige adipocyte number and mitochondrial respiration coincide with reduced FGF21 gene expression in Sprague Dawley rats fed prenatal low protein and …
  1090. Inhibition of insulin resistance by PGE1 via autophagy-dependent FGF21 pathway in diabetic nephropathy Wei Wei, Xing-rong An, Shi-Jie Jin, Xiao-Xue Li, Ming Xu
  1091. Role of PPARα in control of torpor through FGF21-NPY pathway: From circadian clock genes to seasonal change and cardiovascular disease
  1092. The Circulating Furan Fatty Acid Metabolite CMPF Directly Enhances Hepatic FGF21 Secretion and Lipid Metabolism
  1093. FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in …
  1094. Withdrawal: Increased expression of fibroblast growth factor 21 (FGF21) during chronic undernutrition causes growth hormone insensitivity in chondrocytes by …
  1095. High Intensity Aerobic Exercise Activates Hepatic Fatty Acid Metabolism Related to PPARalpha-CREBH-FGF21 Axis in Non-alcoholic Fatty Liver Mice Rater than …
  1096. BIO89-100, a GlycoPEGylated FGF21 Analog, Improved Serum Lipids and Extended Half-Life in a Controlled Single Ascending Dose Trial in Healthy Subjects
  1097. Resveratrol stimulation of SIRT1 & exogenous delivery of FGF21 mimics metformin’s ability to alleviate non-alcoholic fatty liver disease caused by diet-induced obesity
  1098. Fibroblast growth factor 21 (FGF21) response in alcohol induced “acute-on-chronic liver injury”(ACLI) model
  1099. 222-LB: Diabetes Induces Liver Inflammation and FGF21 through C-Jun NH2-Terminal Kinase Pathways
  1100. Fibroblast Growth Factor 21 (FGF21) Mouse (E. coli), Tagless
  1101. 1896-P: Adipocyte-Derived Fibroblast Growth Factor 21 (FGF21) Contributes to Circulating FGF21 Pools in Diet-Induced Obese Mice
  1102. Defining the role of Fibroblast growth factor 21 (FGF21) in the pathogenesis of growth hormone resistance and subsequent growth failure in chronic childhood …
  1103. Understanding the Molecular Basis for FGF15/19 and FGF21 Actions on Energy Homeostasis
  1104. Hormonal Responses that Regulate the Metabolic Benefits of Exercise: The Contribution of the Melanocortin System and the Fibroblast Growth Factor 21 (FGF21) …
  1105. … factor 21 (FGF21) coupled with reduced adipose tissue BetaKlotho and FGF21 receptor 1 (FGFR1) expression in Type 2 diabetes may in part explain FGF21 …
  1106. Fibroblast Growth Factor 21 (FGF21) Mouse (E. coli), His-Tagged
  1107. Pharmaceutical inactivation of Erk1/2 does not affect function of FGF21 to regulate glucose and lipid metabolic hemostasis
  1108. R‐α‐lipoic acid potentiates fasting‐induced transcription and secretion of hepatic fibroblast growth factor 21 (FGF21)
  1109. Fibroblast growth factor 21 (FGF21) has a beneficial effect on carbohydrate and lipid metabolism and taste preferences in male and female mice with diet-induced …
  1110. … protein diet induces body weight loss and browning of subcutaneous white adipose tissue through enhanced expression of hepatic fibroblast growth factor 21 (FGF21 …
  1111. Fibroblast growth factor 21 (FGF21) and diabetes-induced vascular disease
  1112. Anti-adiposity impact of phosphodiesterase-5 inhibitor, Sildenafil is possibly through browning of white adipose tissue and FGF21 in obese rats
  1113. Fibroblast Growth Factor 21 (FGF21) Human (E. coli), Tagless
  1114. MON-163 Lowering of Circulating FGF21 by Modulation of Bile Acid Metabolism in Healthy Males
  1115. The mechanistic role of Fibroblast growth factor 21 (FGF21) in Growth Hormone resistance secondary to chronic childhood conditions
  1116. Sulforaphane Downregulates Hepatic Fibroblast Growth Factor 21 (FGF21) of Diet Induced Obese Mice
  1117. The role of the G-protein coupled receptor 120 (GPR120) on the FGF21 system in white and brown adipose tissues
  1118. Undernutrition and Growth Failure: Is Fibroblast Growth Factor 21 (FGF21) The Missing Link
  1119. Aerobic and Resistance Exercises Modulate Fibroblast Growth Factor-21 (FGF21) Level in Menopause Women with Type II Diabetic
  1120. Fibroblast Growth Factor 21 (FGF21) Human (E. coli), His-Tagged
  1121. Differentiated embryo chondrocyte1 (DEC1) is a novel negative regulator of hepatic Fibroblast growth factor 21 (FGF21) in aging mice
  1122. Combination of metformin plus orlistat prevents tumor progression: novel role of the metabolic hormone fibroblast growth factor 21 (FGF21)
  1123. Reply to Correspondence HEP-15-1008 “AHR-FGF21 dissociation of fatty liver from insulin resistance: a timely matter?”
  1124. The role of metabolic hormone fibroblast growth factor 21 (FGF21) in mammalian hibernation using transgenic ground squirrels
  1125. Research Article Circulating CTRP1 Levels in Type 2 Diabetes and Their Association with FGF21
  1126. 301-LB: Effects of Amino Acid Restriction on Development of Type 2 Diabetes in NZO Mice by FGF21 Secretion
  1127. 300-LB: FGF21 and a ß3-Adrenergic Agonist Synergistically Lower Blood Glucose in Obese Mice at Thermoneutrality
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