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      Ginsenoside
      January 15, 2020
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      Phloretin
      January 15, 2020

       

      Gambogic Acid (Garcinia hanburyi)

      1. Studies on chemical modification and biology of a natural product, gambogic acid (II): Synthesis and bioevaluation of gambogellic acid and its derivatives from gambogic acid as antitumor agents
      2. Inducing cell cycle arrest and apoptosis by dimercaptosuccinic acid modified Fe3O4 magnetic nanoparticles combined with nontoxic concentration of bortezomib and gambogic acid in RPMI-8226 cells
      3. The Next Generation Non-competitive Active Polyester Nanosystems for Transferrin Receptor-mediated Peroral Transport Utilizing gambogic acid as a Ligand
      4. Crystallization of Pseudopolymorphs of Some Gamboge Pigments. Pyridine, Dimethylformamide and Dimethylsulfoxide Solvates of Morellic Acid, gambogic acid and Guttiferic Acid
      5. Studies on chemical structure modification and biology of a natural product, gambogic acid (I): Synthesis and biological evaluation of oxidized analogues of gambogic acid
      6. 1213901. Synthesis and anti-tumor activity of NO-donating derivatives of gambogic acid
      7. 345. Gamboge. Part I. The constitutions of the acids C 11 H 10 O 4 and C 12 H 10 O 6 derived from gambogic acid
      8. 47 gambogic acid delivery using lipid nanoparticles modified with cell-penetrating peptide
      9. A novel dual sensitive polymer-gambogic acid conjugate: synthesis, characterization, and in vitro evaluation
      10. A novel exploration of a combination of gambogic acid with TiO2 nanofibers: The photodynamic effect for HepG2 cell proliferation
      11. A novel redox/pH dual-responsive and hyaluronic acid-decorated multifunctional magnetic complex micelle for targeted gambogic acid delivery for the treatment of …
      12. A Probe into mechanism of gambogic acid-induced apoptosis in SPC-A-1 lung adenocarcinoma cells [J]
      13. A role for transferrin receptor in triggering apoptosis when targeted with gambogic acid
      14. A solvent-assisted active loading technology to prepare gambogic acid and all-trans retinoic acid co-encapsulated liposomes for synergistic anticancer therapy
      15. Absolute configuration of (−)-gambogic acid, an antitumor agent
      16. Abstract# 4392: Role of transferrin receptor 1 and Src in gambogic acid-induced apoptosis
      17. Advance on Mechanisms in Antitumor Effect of gambogic acid and Its Derivates [J]
      18. Aminated β-cyclodextrin-grafted Fe 3 O 4-loaded gambogic acid magnetic nanoparticles: preparation, characterization, and biological evaluation
      19. Aminated β-cyclodextrin-grafted Fe₃O₄-loaded gambogic acid magnetic nanoparticles: preparation, characterization, and biological evaluation
      20. An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors
      21. An open-labeled, randomized, multicentered, phase IIa study for advanced cancer treatment by gambogic acid injection (THS).
      22. An oxidative analogue of gambogic acid-induced apoptosis of human hepatocellular carcinoma cell line HepG2 is involved in its anticancer activity in vitro
      23. Anticancer effect and apoptosis induction of gambogic acid in human gastric cancer line BGC-823
      24. Anticancer effect and apoptosis induction of gambogic acid in human leukemia cell line K562 in vitro
      25. Anticancer effect of gambogic acid in gastric cancer line SGC-7901
      26. Anti-CD22-conjugated CdTe QDs co-loaded with doxorubicin and gambogic acid: a novel platform for lymphoma treatment
      27. Anti-EGFR-iRGD recombinant protein modified biomimetic nanoparticles loaded with gambogic acid to enhance targeting and antitumor ability in colorectal …
      28. Anti‑inflammatory effects of gambogic acid in murine collagen‑induced arthritis through PI3K/Akt signaling pathway
      29. Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells
      30. Antimetastatic Effects of gambogic acid are Mediated via the Actin Cytoskeleton and NF‐κ B Pathways in SK‐HEP 1 Cells
      31. Antiproliferative activity of gambogic acid isolated from Garcinia hanburyi in Hep3B and Huh7 cancer cells
      32. Antitumor activity of gambogic acid on NCI-H1993 xenografts via MET signaling pathway downregulation
      33. Apoptosis induction associated with the ER stress response through up-regulation of JNK in HeLa cells by gambogic acid
      34. Apoptosis-inducing effect of gambogic acid on K562 cells and its mechanism
      35. Apoptotic effect of gambogic acid in esophageal squamous cell carcinoma cells via suppression of the NF-κB pathway
      36. Application of Probe Drugs for Detecting Influences of gambogic acid on Cytochrome P450 Isoforms
      37. Autophagy inhibition promotes gambogic acid-induced suppression of growth and apoptosis in glioblastoma cells
      38. Bromodomain‑containing protein 4 is critical for the antiproliferative and pro‑apoptotic effects of gambogic acid in anaplastic thyroid cancer
      39. Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation
      40. Caspase-8 preferentially senses the apoptosis-inducing action of NG-18, a gambogic acid derivative, in human leukemia HL-60 cells
      41. CD44 targeted redox-triggered self-assembly with magnetic enhanced EPR effects for effective amplification of gambogic acid to treat triple-negative breast cancer
      42. Cell penetrating peptides functionalized gambogic acid-nanostructured lipid carrier for cancer treatment
      43. Cell-penetrating peptide conjugates of gambogic acid enhance the antitumor effect on human bladder cancer EJ cells through ROS-mediated apoptosis
      44. Co-delivery of gambogic acid and TRAIL plasmid by hyaluronic acid grafted PEI-PLGA nanoparticles for the treatment of triple negative breast cancer
      45. Combination of gambogic acid with cisplatin enhances the antitumor effects on cisplatin-resistant lung cancer cells by downregulating MRP2 and LRP …
      46. Combined therapy with EGFR TKI and gambogic acid for overcoming resistance in EGFR‑T790M mutant lung cancer
      47. Comparative studies on biophysical interactions between gambogic acid and serum albumin via multispectroscopic approaches and molecular docking
      48. Comparison of electron capture—atmospheric pressure chemical ionization and electrospray ionization for the analysis of gambogic acid and its main circulating …
      49. Computational study on the conformations of gambogic acid
      50. Crystal structure of the pyridine salt of gambogic acid
      51. Cytotoxic effect of gambogic acid on SH-SY5Y neuroblastoma cells is mediated by intrinsic caspase-dependent signaling pathway
      52. Daunorubicin and gambogic acid coloaded cysteamine-CdTe quantum dots minimizing the multidrug resistance of lymphoma in vitro and in vivo
      53. Design and synthesis of gambogic acid analogs as potent cytotoxic and anti-inflammatory agents
      54. Determination of Content and Entrapment Efficiency of Neo-gambogic acid Nanoparticles by HPLC
      55. Determination of gambogic acid in dog plasma by high‐performance liquid chromatography for a pharmacokinetic study
      56. Determination of gambogic acid in Gamboge by non-aqueous capillary electrophoresis
      57. Determination of gambogic acid in human plasma by liquid chromatography-atmospheric pressure chemical ionization–mass spectrometry
      58. Determination of the content of gambogic acid and gambogenic acid in gamboge by HPLC
      59. Determination of the Content of gambogic acid and Neo-gambogic acid in Gamboge by HPLC
      60. Determination of Total gambogic acid in Gamboge by ZrOCl_2 Colorimetry
      61. Development of a more efficient albumin-based delivery system for gambogic acid with low toxicity for lung cancer therapy
      62. Development of a safety and efficacy nanoemulsion delivery system encapsulated gambogic acid for acute myeloid leukemia in vitro and in vivo
      63. Differential apoptotic induction of gambogic acid, a novel anticancer natural product, on hepatoma cells and normal hepatocytes
      64. Dimeric c (RGD) peptide conjugated nanostructured lipid carriers for efficient delivery of gambogic acid to breast cancer
      65. Discovery, characterization and SAR of gambogic acid as a potent apoptosis inducer by a HTS assay
      66. Down-regulation of chemokine receptor CXCR4 by gambogic acid suppresses metastasis of pancreatic cancer in an orthotopic mouse model
      67. Effect of gambogic acid on cell apoptosis and expressions of Bax, Bcl-2 and Caspase-3 in colorectal cancer cells with
      68. Effect of gambogic acid on proliferation and apoptosis in 786-O cells
      69. Effect of gambogic acid on proliferation and apoptosis of human diffuse large B-cell lymphoma cell line OCI-LY-1
      70. Effect of gambogic acid on proliferation and invasion in colon cancer LoVo cell line
      71. Effect of gambogic acid on proliferation of SKM-1 cells and its mechanism
      72. Effect of gambogic acid on the proliferation of human colon carcinoma cell SW480 and the expression of VEGFR2 [J]
      73. Effect of gambogic acid on the regulation of hERG channel in K562 cells in vitro
      74. Effect on proliferation and apoptosis and regulation on nucleoporin Nup88 in acute leukemic cell U937 by gambogic acid
      75. Effects of gambogic acid on Bladder Cancer Cells
      76. Effects of gambogic acid on human telomerase reverse transcriptase and Bcl-2 protein in human osteosarcoma cells
      77. Effects of gambogic acid on regulation of steroid receptor coactivator-3 in lung adenocarcinoma A549 cells
      78. Effects of gambogic acid on the activation of caspase-3 and downregulation of SIRT1 in RPMI-8226 multiple myeloma cells via the accumulation of ROS
      79. Effects of gambogic acid on the Production of Reactive Oxygen Species and Neutrophil Extracellular Traps
      80. EFFECTS OF gambogic acid ON THE PROLIFERATION AND CELL APOPTOSIS OF CELL LINE NCI-H929IN MULTIPLE MYELOMA
      81. Effects of gambogic acid on the regulation of nucleoporin Nup88 in HL-60 cells
      82. Effects of gambogic acid on the regulation of nucleoporin Nup88 in U937 cells
      83. Effects of gambogic acid on the regulation of steroid receptor coactivator-3 in A549 cells
      84. Effects of magnetic nanoparticle Fe_3O_4 on apoptosis of HepG2 cells induced by gambogic acid
      85. Effects of magnetic nanoparticle of Fe3O4 on apoptosis induced by gambogic acid in U937 leukemia cells.
      86. Effects of magnetic nanoparticles of Fe3O4 combinated with gambogic acid on apoptosis of SMMC-7721 cells
      87. Enhanced cytotoxicity of an anti-transferrin receptor IgG3-avidin fusion protein in combination with gambogic acid against human malignant hematopoietic …
      88. Enhancement of anticancer efficacy of chemotherapeutics by gambogic acid against gastric cancer cells
      89. Evaluation of in vitro and in vivo antitumor effects of gambogic acid-loaded layer-by-layer self-assembled micelles
      90. Experimental study on effects of gambogic acid with cisplatin to human osteosarcoma cells
      91. Experimental study on gambogic acid-induced gastric cancer cell apoptosis and anti-tumor metastasis
      92. Experimental study on gambogic acid-induced gastric cancer cell apoptosis and anti-tumor metastasis.
      93. Exploration of acute genotoxic effects and antigenotoxic potential of gambogic acid using Allium cepa assay
      94. Fine-tuning vitamin E-containing telodendrimers for efficient delivery of gambogic acid in colon cancer treatment
      95. Folate‐decorated arginine‐based poly (ester urea urethane) nanoparticles as carriers for gambogic acid and effect on cancer cells
      96. Functional inhibition of Hsp70 by Pifithrin-μ switches gambogic acid induced caspase dependent cell death to caspase independent cell death in human …
      97. GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms
      98. Gamboge. Part IV. Scission of gambogic acid by alkali
      99. gambogic acid
      100. gambogic acid activates AMP-activated protein kinase in mammalian cells
      101. gambogic acid Affects Ribosomal Occurrence in Glioma Cells by Downregulating the Phosphoinositide Kinase-3/Protein Kinase B/Mammalian Target of Rapamycin …
      102. gambogic acid ameliorates diabetes-induced proliferative retinopathy through inhibition of the HIF-1α/VEGF expression via targeting PI3K/AKT pathway
      103. gambogic acid ameliorates diabetes-induced proliferative retinopathy through inhibition of the HIF-1α/VEGF expression via targeting PI3K/AKT pathway
      104. gambogic acid and celastrol are two powerful anti-inflammatory drugs in arthritis
      105. gambogic acid and epigambogic acid, C-2 epimers with novel anticancer effects from Garcinia hanburyi
      106. gambogic acid and inhibition of tumor growth: a close association
      107. gambogic acid and its analogs inhibit gap junctional intercellular communication
      108. gambogic acid and its role in chronic diseases
      109. gambogic acid as a Non‐Competitive Inhibitor of ATP‐Binding Cassette Transporter B1 Reverses the Multidrug Resistance of Human Epithelial Cancers by …
      110. gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90
      111. gambogic acid binds to human CB2 receptors and exhibits potential partial agonist activity
      112. gambogic acid causes fin developmental defect in zebrafish embryo partially via retinoic acid signaling
      113. gambogic acid combined with CdTe QDs for leukemia cancer cells inhibition and their bio-safety for rat brain
      114. gambogic acid counteracts mutant p53 stability by inducing autophagy
      115. gambogic acid covalently interacts with IKK-2 to inhibit the NF-kB signaling pathway
      116. gambogic acid covalently modifies IκB kinase-β subunit to mediate suppression of lipopolysaccharide-induced activation of NF-κB in macrophages
      117. gambogic acid deactivates cytosolic and mitochondrial thioredoxins by covalent binding to the functional domain
      118. gambogic acid disrupts toll-like receptor4 activation by blocking lipopolysaccharides binding to myeloid differentiation factor 2
      119. gambogic acid down-regulates MDM2 oncogene and induces p21Waf1/CIP1 expression independent of p53
      120. gambogic acid efficiently kills stem-like colorectal cancer cells by upregulating zfp36 expression
      121. gambogic acid enhances proteasome inhibitor-induced anticancer activity
      122. gambogic acid enhances the radiosensitivity of human esophageal cancer cells by inducing reactive oxygen species via targeting Akt/mTOR pathway
      123. gambogic acid exerts cardioprotective effects in a rat model of acute myocardial infarction through inhibition of inflammation, iNOS and NF‑κB/p38 pathway
      124. gambogic acid exhibits anti-metastatic activity on malignant melanoma mainly through inhibition of PI3K/Akt and ERK signaling pathways
      125. gambogic acid exhibits anti-psoriatic efficacy through inhibition of angiogenesis and inflammation
      126. gambogic acid grafted low molecular weight heparin micelles for targeted treatment in a hepatocellular carcinoma model with an enhanced anti-angiogenesis effect
      127. gambogic acid identifies an isoform-specific druggable pocket in the middle domain of Hsp90β
      128. gambogic acid impairs tumor angiogenesis by targeting YAP/STAT3 signaling axis
      129. gambogic acid improves non-small cell lung cancer progression by inhibition of mTOR signaling pathway
      130. gambogic acid increases the sensitivity to paclitaxel in drug‑resistant triple‑negative breast cancer via the SHH signaling pathway
      131. gambogic acid Induced Apoptosis through Activation of Caspase-dependent Pathway in Aortic Smooth Muscle Cells
      132. gambogic acid induced oxidative stress dependent caspase activation regulates both apoptosis and autophagy by targeting various key molecules (NF-κB, Beclin-1 …
      133. gambogic acid induced tumor cell apoptosis by T lymphocyte activation in H22 transplanted mice
      134. gambogic acid induces apoptosis and inhibits colorectal tumor growth via mitochondrial pathways
      135. gambogic acid induces apoptosis and regulates expressions of Bax and Bcl-2 protein in human gastric carcinoma MGC-803 cells
      136. gambogic acid induces apoptosis and sensitizes TRAIL-mediated apoptosis through downregulation of cFLIPL in renal carcinoma Caki cells
      137. gambogic acid induces apoptosis by regulating the expression of Bax and Bcl‐2 and enhancing caspase‐3 activity in human malignant melanoma A375 cells
      138. gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition
      139. gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase
      140. gambogic acid Induces Apoptosis in Imatinib-Resistant
      141. gambogic acid induces apoptosis in imatinib-resistant chronic myeloid leukemia cells via inducing proteasome inhibition and caspase-dependent Bcr-Abl …
      142. gambogic acid induces apoptosis of human malignant melanoma A375 cells
      143. gambogic acid induces apoptosis of Jurkat cell through the MAPK signal pathway
      144. gambogic acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling
      145. gambogic acid induces apoptosis of SK-MES-1 lung cancer cells
      146. gambogic acid induces apoptotic cell death in T98G glioma cells
      147. gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive …
      148. gambogic acid Induces Cell Apoptosis and Inhibits MAPK Pathway in PTEN−/−/p53−/− Prostate Cancer Cells In Vitro and Ex Vivo
      149. gambogic acid induces cell apoptosis through endoplasmic reticulum stress triggered inhibition of Akt signaling pathways in extranodal NK/T-cell lymphoma cells
      150. gambogic acid induces death inducer‐obliterator 1‐mediated apoptosis in Jurkat T cells
      151. gambogic acid induces death of K562 cells through autophagy and apoptosis mechanisms
      152. gambogic acid induces EGFR degradation and Akt/mTORC1 inhibition through AMPK dependent-LRIG1 upregulation in cultured U87 glioma cells
      153. gambogic acid induces G0/G1 arrest and apoptosis involving inhibition of SRC-3 and inactivation of Akt pathway in K562 leukemia cells
      154. gambogic acid induces G0/G1 cell cycle arrest and cell migration inhibition via suppressing PDGF receptor β tyrosine phosphorylation and Rac1 activity in rat aortic …
      155. gambogic acid induces growth inhibition and differentiation via upregulation of p21waf1/cip1 expression in acute myeloid leukemia cells
      156. gambogic acid induces heme oxygenase-1 through Nrf2 signaling pathway and inhibits NF-κB and MAPK activation to reduce inflammation in LPS-activated …
      157. gambogic acid induces mitochondria-dependent apoptosis by modulation of Bcl-2 and Bax in mantle cell lymphoma JeKo-1 cells
      158. gambogic acid induces Raji cell apoptosis in vitro and its mechanism
      159. gambogic acid induces the apoptosis an d arrests thec ycleo f human bladder cancer cells
      160. gambogic acid induces the apoptosis and autophagic cell death in human hepatoma cells
      161. gambogic acid inhibits angiogenesis and prostate tumor growth by suppressing vascular endothelial growth factor receptor 2 signaling
      162. gambogic acid inhibits angiogenesis through inhibiting PHD2–VHL–HIF-1α pathway
      163. gambogic acid inhibits angiogenesis through suppressing vascular endothelial growth factor-induced tyrosine phosphorylation of KDR/Flk-1
      164. gambogic acid inhibits cell proliferation via suppressing epithelial growth factor receptor tyrosine phosphorylation in rat aortic smooth muscle cell
      165. gambogic acid inhibits chemokine receptor CXCR4 signaling pathways and osteoclastogenesis in multiple myeloma
      166. gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells
      167. gambogic acid inhibits Hsp90 and deregulates TNF-α/NF-κB in HeLa cells
      168. gambogic acid inhibits Hsp90 and deregulates TNF-α/NF-κB in HeLa cells.
      169. gambogic acid inhibits Hsp90 expressions in thiram-induced tibial dyschondroplasia
      170. gambogic acid inhibits invasion of osteosarcoma via upregulation of TIMP-1
      171. gambogic acid inhibits LPS-induced macrophage pro-inflammatory cytokine production mainly through suppression of the p38 pathway
      172. gambogic acid inhibits malignant melanoma cell proliferation through mitochondrial p66shc/ROS-p53/Bax-mediated apoptosis
      173. gambogic acid Inhibits Melanoma through Regulation of miR‐199a‐3p/ZEB1 Signalling
      174. gambogic acid inhibits multiple myeloma mediated osteoclastogenesis through suppression of chemokine receptor CXCR4 signaling pathways
      175. gambogic acid inhibits osteoclast formation and ovariectomy-induced osteoporosis by suppressing the JNK, p38 and Akt signalling pathways
      176. gambogic acid inhibits proliferation of human lung carcinoma SPC-A1 cells in vivo and in vitro and represses telomerase activity and telomerase reverse transcriptase …
      177. gambogic acid inhibits spinal cord injury and inflammation through suppressing the p38 and Akt signaling pathways
      178. gambogic acid inhibits STAT3 phosphorylation through activation of protein tyrosine phosphatase SHP-1: potential role in proliferation and apoptosis
      179. gambogic acid inhibits the catalytic activity of human topoisomerase IIα by binding to its ATPase domain
      180. gambogic acid inhibits the growth of osteosarcoma cells in vitro by inducing apoptosis and cell cycle arrest
      181. gambogic acid inhibits the growth of ovarian cancer tumors by regulating p65 activity
      182. gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer
      183. gambogic acid inhibits TNF-α-induced invasion of human prostate cancer PC3 cells in vitro through PI3K/Akt and NF-κB signaling pathways
      184. gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway
      185. gambogic acid is a novel anti-cancer agent that inhibits cell proliferation, angiogenesis and metastasis
      186. gambogic acid is a tissue-specific proteasome inhibitor in vitro and in vivo
      187. gambogic acid is an antagonist of antiapoptotic Bcl-2 family proteins
      188. gambogic acid is cytotoxic to cancer cells through inhibition of the ubiquitin-proteasome system
      189. gambogic acid lysinate induces apoptosis in breast cancer MCF-7 cells by increasing reactive oxygen species
      190. gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells
      191. gambogic acid mediates transferrin receptor-1 phosphorylation leading to jnk-dependant apoptosis
      192. gambogic acid moderates cardiac responses to chronic hypoxia likely by acting on the proteasome and NF-κB pathway
      193. gambogic acid potentiates clopidogrel-induced apoptosis and attenuates irinotecan-induced apoptosis through down-regulating human carboxylesterase 1 and-2
      194. gambogic acid potentiates the chemosensitivity of colorectal cancer cells to 5‑fluorouracil by inhibiting proliferation and inducing apoptosis
      195. gambogic acid prevents angiotensin II‑induced abdominal aortic aneurysm through inflammatory and oxidative stress dependent targeting the PI3K/Akt/mTOR and NF …
      196. gambogic acid promotes apoptosis and resistance to metastatic potential in MDA-MB-231 human breast carcinoma cells
      197. gambogic acid protects from endotoxin shock by suppressing pro-inflammatory factors in vivo and in vitro
      198. gambogic acid reduced bcl-2 expression via p53 in human breast MCF-7 cancer cells
      199. gambogic acid regulates the migration and invasion of colorectal cancer via microRNA‑21‑mediated activation of phosphatase and tensin homolog
      200. gambogic acid reverses oxaliplatin resistance in colorectal cancer by increasing intracellular platinum levels
      201. gambogic acid sensitizes breast cancer cells to TRAIL-induced apoptosis by promoting the crosstalk of extrinsic and intrinsic apoptotic signalings
      202. gambogic acid sensitizes gemcitabine efficacy in pancreatic cancer by reducing the expression of ribonucleotide reductase subunit-M2 (RRM2)
      203. gambogic acid sensitizes ovarian cancer cells to doxorubicin through ROS-mediated apoptosis
      204. gambogic acid sensitizes resistant breast cancer cells to doxorubicin through inhibiting P-glycoprotein and suppressing survivin expression
      205. gambogic acid Shows Anti-Proliferative Effects on Non-Small Cell Lung Cancer (NSCLC) Cells by Activating Reactive Oxygen Species (ROS)-Induced …
      206. gambogic acid suppresses cancer invasion and migration by inhibiting TGFβ1-induced epithelial-to-mesenchymal transition
      207. gambogic acid suppresses colon cancer cell activity in vitro
      208. gambogic acid suppresses cytochrome P450 3A4 by downregulating pregnane X receptor and up-regulating DEC1 in human hepatoma HepG2 cells
      209. gambogic acid suppresses hypoxia‐induced hypoxia‐inducible factor‐1α/vascular endothelial growth factor expression via inhibiting phosphatidylinositol 3‐kinase …
      210. gambogic acid suppresses inflammation in rheumatoid arthritis rats via PI3K/Akt/mTOR signaling pathway
      211. gambogic acid suppresses pressure overload cardiac hypertrophy in rats
      212. gambogic acid synergistically potentiates cisplatin-induced apoptosis in non-small-cell lung cancer through suppressing NF-κB and MAPK/HO-1 signalling
      213. gambogic acid triggers DNA damage signaling that induces p53/p21Waf1/CIP1 activation through the ATR-Chk1 pathway
      214. gambogic acid triggers vacuolization-associated cell death in cancer cells via disruption of thiol proteostasis
      215. gambogic acid, a natural product inhibitor of Hsp90
      216. gambogic acid, a potent inhibitor of survivin, reverses docetaxel resistance in gastric cancer cells
      217. gambogic acid: A Caged Prenylated Garcinia Xanthone: Potent Anticancer Agent of Pharmaceutical Promise
      218. gambogic acid-encapsulated polymeric micelles improved therapeutic effects on pancreatic cancer
      219. gambogic acid-induced autophagy in nonsmall cell lung cancer NCI-H441 cells through a reactive oxygen species pathway
      220. gambogic acid‐induced degradation of mutant p53 is mediated by proteasome and related to CHIP
      221. gambogic acid-induced G 2 /M phase cell-cycle arrest via disturbing CDK7-mediated phosphorylation of CDC2/p34 in human gastric carcinoma BGC …
      222. gambogic acid-loaded biomimetic nanoparticles in colorectal cancer treatment
      223. gambogic acid-loaded electrosprayed particles for site-specific treatment of hepatocellular carcinoma
      224. gambogic acid-loaded magnetic Fe3O4 nanoparticles inhibit Panc-1 pancreatic cancer cell proliferation and migration by inactivating transcription factor …
      225. gambogic acid-loaded PEG–PCL nanoparticles act as an effective antitumor agent against gastric cancer
      226. gambogic acid-loaded pH-sensitive mixed micelles for overcoming breast cancer resistance
      227. gambogic acid-loaded polymeric micelles for improved therapeutic effect in breast cancer
      228. General pharmacological properties, developmental toxicity, and analgesic activity of gambogic acid, a novel natural anticancer agent
      229. Global profiling of cellular targets of gambogic acid by quantitative chemical proteomics
      230. Hyaluronic acid-decorated redox-sensitive chitosan micelles for tumor-specific intracellular delivery of gambogic acid
      231. Hypoxia-induced resistance to cisplatin-mediated apoptosis in osteosarcoma cells is reversed by gambogic acid independently of HIF-1α
      232. Identification and quantitative determination of a major circulating metabolite of gambogic acid in human
      233. Identification of gambogic acid metabolites in rat bile by liquid chromatography-tandem mass spectrometry-ion trap-time-of-flight
      234. Improved druggability of gambogic acid using core–shell nanoparticles
      235. Improving aqueous solubility and antitumor effects by nanosized gambogic acid-mPEG2000 micelles
      236. Inclusion complex from cyclodextrin-grafted hyaluronic acid and pseudo protein as biodegradable nano-delivery vehicle for gambogic acid
      237. Induction of programmed erythrocyte death by gambogic acid
      238. Inhibition effect of gambogic acid on MUTZ-1 cell line and its possible mechanism
      239. Inhibition of glioblastoma growth and angiogenesis by gambogic acid: an in vitro and in vivo study
      240. Inhibition of human telomerase reverse transcriptase gene expression by gambogic acid in human hepatoma SMMC-7721 cells
      241. Inhibition of inwardly rectifying Kir2.x channels by the novel anti-cancer agent gambogic acid depends on both pore block and PIP2 interference
      242. Inhibition of Murine Macrophage Inwardly Rectifying Kir2. 1 Channels by gambogic acid
      243. Inhibition of α4 integrin mediated adhesion was involved in the reduction of B16-F10 melanoma cells lung colonization in C57BL/6 mice treated with gambogic acid
      244. Interaction between gambogic acid and dihydrofolate reductase and synergistic lethal effects with methotrexate on hepatoma cells
      245. Involvement of E-cadherin/AMPK/mTOR axis in LKB1-induced sensitivity of non-small cell lung cancer to gambogic acid
      246. Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis
      247. Involvement of RECK in gambogic acid induced anti‐invasive effect in A549 human lung carcinoma cells
      248. Involvement of Regulations of Nucleophosmin and Nucleoporins in gambogic acid‐Induced Apoptosis in Jurkat Cells
      249. Isolation and structure of neo-gambogic acid from Gamboge (Garcinia hanburryi)
      250. Magnetic and CD44 receptor dual targeting redox-responsive polymeric micelle for precise delivery of gambogic acid to triple-negative breast cancer
      251. Mechanism of gambogic acid-induced apoptosis in Raji cells
      252. Mechanisms of gambogic acid-induced apoptosis in non-small cell lung cancer cells in relation to transferrin receptors
      253. Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes
      254. Metabolism of gambogic acid in rats: a rare intestinal metabolic pathway responsible for its final disposition
      255. Methyl jasmonate sensitizes human bladder cancer cells to gambogic acid‐induced apoptosis through down‐regulation of EZH 2 expression by miR‐101
      256. Michael acceptor in gambogic acid—Its role and application for potent antitumor agents
      257. Microtubule depolymerization and phosphorylation of c-Jun N-terminal kinase-1 and p38 were involved in gambogic acid induced cell cycle arrest and apoptosis in …
      258. Modified chitosan derivative micelle system for natural anti-tumor product gambogic acid delivery
      259. Molecular formula and identity of β-guttiferin and α-gambogic acid
      260. Molecular targets of gambogic acid in cancer: recent trends and advancements
      261. Multifunctional effects of Cys–CdTe QDs conjugated with gambogic acid for cancer cell tracing and inhibition
      262. Nanodelivery of gambogic acid by functionalized graphene enhances inhibition of cell proliferation and induces G 0/G 1 cell cycle arrest in cervical, ovarian, and …
      263. Nanodelivery of gambogic acid by functionalized graphene enhances inhibition of cell proliferation and induces G₀/G₁ cell cycle arrest in cervical, ovarian, and …
      264. Nanomedicine-based combination of gambogic acid and retinoic acid chlorochalcone for enhanced anticancer efficacy in osteosarcoma
      265. Nanoparticle delivery and combination therapy of gambogic acid and all-trans retinoic acid
      266. Nanoparticles with optimal ratiometric co-delivery of docetaxel with gambogic acid for treatment of multidrug-resistant breast cancer
      267. New targets for the antitumor activity of gambogic acid in hematologic malignancies
      268. Next-Generation Noncompetitive Nanosystems Based on gambogic acid: In Silico Identification of Transferrin Receptor Binding Sites, Regulatory Shelf Stability, and …
      269. N-octyl-N-arginine-chitosan (OACS) micelles for gambogic acid oral delivery: preparation, characterization and its study on in situ intestinal perfusion
      270. N-octyl-N-arginine-chitosan micelles for gambogic acid intravenous delivery: characterization, cell uptake, pharmacokinetics, and biodistribution
      271. Novel long-circulating liposomes consisting of PEG modified β-sitosterol for gambogic acid delivery
      272. Optimization of Extracting Process of Neo-gambogic acid [J]
      273. Optimization of Extraction Process of gambogic acid [J]
      274. Optimization of the formulation of gambogic acid nanosuspensions by the central composite design-response surface methodology
      275. Optimizing extraction process of neo-gambogic acid from gamboge by orthogonal test [J]
      276. PEG prodrug of gambogic acid: Amino acid and dipeptide spacer effects
      277. PEG–PLGA–PLL nanoparticles in combination with gambogic acid for reversing multidrug resistance of K562/A02 cells to daunorubicin
      278. Pharmacokinetics and Tissue Distribution Study of gambogic acid and gambogic acid Nanosuspension in Mice by UHPLC–MS/MS
      279. Pharmacokinetics of gambogic acid in rats
      280. Pharmacokinetics, tissue distribution and excretion of gambogic acid in rats
      281. PhaseⅠhuman tolerability trial of gambogic acid
      282. Pluronic F68-linoleic acid nano-spheres mediated delivery of gambogic acid for cancer therapy
      283. Poloxamer 407/TPGS mixed micelles for delivery of gambogic acid to breast and multidrug-resistant cancer
      284. Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells
      285. Potent anti-inflammatory and antiproliferative effects of gambogic acid in a rat model of antigen-induced arthritis
      286. Preparation, physical properties, and stability of gambogic acid-loaded micelles based on chitosan derivatives
      287. Preparative separation of gambogic acid and its C-2 epimer using recycling high-speed counter-current chromatography
      288. Progress in the Effect of Anti-tumor Molecular Targets of gambogic acid [J]
      289. Protective role of gambogic acid in experimental pulmonary fibrosis in vitro and in vivo
      290. Proteomic analysis revealed the important role of vimentin in human cervical carcinoma HeLa cells treated with gambogic acid
      291. Proteomic and bioinformatic analyses of possible target-related proteins of gambogic acid in human breast carcinoma MDA-MB-231 cells
      292. Proteomic identification of molecular targets of gambogic acid: role of stathmin in hepatocellular carcinoma
      293. Quantitative cardiotoxicity assessment of gambogic acid using multiple cellular phenotype analysis
      294. Radioiodinated of gambogic acid and its biodistribution in mice
      295. Rational Design of GO-Modified Fe3O4/SiO2 Nanoparticles with Combined Rhenium-188 and gambogic acid for Magnetic Target Therapy
      296. Reactive oxygen species accumulation contributes to gambogic acid-induced apoptosis in human hepatoma SMMC-7721 cells
      297. Redox-responsive polymeric micelles formed by conjugating gambogic acid with bioreducible poly (amido amine) s for the co-delivery of docetaxel and MMP-9 …
      298. Regulation of gambogic acid on hERG potassium channel protein of K562 leukemia cells [J]
      299. Repression of telomerase reverse transcriptase mRNA and hTERT promoter by gambogic acid in human gastric carcinoma cells
      300. Research progress of gambogic acid as active ingredient of traditional Chinese medicine (TCM) gamboge
      301. Research progress of gambogic acid in tumor.
      302. Reversal effect of gambogic acid on multidrug resistance of K562/A02 cell line
      303. Role of chloride channels in gambogic acid-induced apoptosis of poorly differentiated nasopharyngeal carcinoma cells
      304. Role of gambogic acid and NaI131 in A549/DDP cells
      305. Role of gambogic acid in Chemosensitization of Cancer
      306. ROS-mediated autophagy induced by dysregulation of lipid metabolism plays a protective role in colorectal cancer cells treated with gambogic acid
      307. Screening for natural compounds with anticancer activity in colon cancer cells identifies cytotoxic gambogic acid analogues
      308. Selective anti-proliferative effect of an anti-transferrin receptor IgG3-avidin fusion protein and gambogic acid in a panel of hematopoietic malignant cell lines
      309. Silencing pyruvate kinase M2 sensitizes human prostate cancer PC3 cells to gambogic acid-induced apoptosis
      310. Simultaneous determination and pharmacokinetic study of gambogic acid and gambogenic acid in rat plasma after oral administration of Garcinia hanburyi extracts …
      311. Single‐walled carbon nanotube and graphene nanodelivery of gambogic acid increases its cytotoxicity in breast and pancreatic cancer cells
      312. Single-walled carbon nanotube and graphene: Nano-delivery of gambogic acid increases its cytotoxicty in various cancer cells
      313. Solubility measurement and RESOLV-assisted nanonization of gambogic acid in supercritical carbon dioxide for cancer therapy
      314. Specific and slow inhibition of the kir2. 1 K+ channel by gambogic acid
      315. Spectacular modification of gambogic acid on microwave irradiation in methanol: Isolation and structure identification of two products with potent anti-tumor activity
      316. Stability and cytotoxicity of gambogic acid and its derivative, gambogoic acid
      317. Steroid receptor coactivator-3 is a pivotal target of gambogic acid in B-cell Non-Hodgkin lymphoma and an inducer of histone H3 deacetylation
      318. Structure elucidation of metabolites of gambogic acid in vivo in rat bile by high-performance liquid chromatography–mass spectrometry and high-performance liquid …
      319. Structure-activity relationship of gambogic acid
      320. Studies on chemical modification and biology of a natural product, gambogic acid (III): determination of the essential pharmacophore for biological activity
      321. Studies on Chemical Structure Modification and Structure Activity Relationship of Derivatives of gambogic acid at C (39)
      322. Studies on Chemical‐Structure Modification and Structure Activity Relationship of gambogic acid Derivatives at Carbon (34)
      323. Studies on gambogic acid (IV): Exploring structure–activity relationship with IκB kinase-beta (IKKβ)
      324. Studies on lactoferrin nanoparticles of gambogic acid for oral delivery
      325. Studies on preparation and stability of human serum albumin nanoparticles containing gambogic acid
      326. Studies on the toxicity of gambogic acid in rats
      327. Study of the enhanced anticancer efficacy of gambogic acid on Capan-1 pancreatic cancer cells when mediated via magnetic Fe3O4 nanoparticles
      328. Study on gambogic acid-loaded Polylacticacid Nanoparticles
      329. Study on gambogic acid-loaded Polylacticacid Nanoparticles [J]
      330. Study on intestinal absorption kinetics of gambogic acid in rats
      331. Study progress on anti-tumor mechanism of gambogic acid [J]
      332. Subcellular localization and activity of gambogic acid
      333. Suppression of APC production during apoptosis of human colorectal cancer cell line SW480 induced by gambogic acid [J]
      334. Suppression of NF-κB signaling and P-glycoprotein function by gambogic acid synergistically potentiates adriamycin-induced apoptosis in lung cancer
      335. Synergetic effect of functional cadmium–tellurium quantum dots conjugated with gambogic acid for HepG2 cell-labeling and proliferation inhibition
      336. Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines
      337. Synergistic effect of 5-fluorouracil with gambogic acid on BGC-823 human gastric carcinoma
      338. Synergistic effect of a combination of nanoparticulate Fe3O4 and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells
      339. Synergistic effect of magnetic nanoparticles of Fe3O4 with gambogic acid on apoptosis of K562 leukemia cells
      340. Synthesis and antiangiogenic activity of novel gambogic acid derivatives
      341. Synthesis and antitumor activities of structure-related small molecular compounds of gambogic acid
      342. Synthesis and anti-tumor activity of NO-donating derivatives of gambogic acid
      343. Synthesis and Anti‐tumor Evaluation of B‐ring Modified Caged Xanthone Analogues of gambogic acid
      344. Synthesis and Anti-tumor Evaluation of Nitrile-Containing gambogic acid Derivatives
      345. Synthesis and Anti‐tumor Evaluation of Novel C‐37 Modified Derivatives of gambogic acid
      346. Synthesis and biological evaluation of novel derivatives of gambogic acid as anti-hepatocellular carcinoma agents
      347. Synthesis and evaluation of gambogic acid derivatives as antitumor agents. Part III
      348. Synthesis of caged 2, 3, 3a, 7a-tetrahydro-3, 6-methanobenzofuran-7 (6H)-ones: Evaluating the minimum structure for apoptosis induction by gambogic acid
      349. Systemic study of solvent-assisted active loading of gambogic acid into liposomes and its formulation optimization for improved delivery
      350. Targeting renal cell carcinoma with gambogic acid in combination with sunitinib in vitro and in vivo
      351. The combination of proteasome inhibitors bortezomib and gambogic acid triggers synergistic cytotoxicity in vitro but not in vivo
      352. The constitution of gambogic acid
      353. The growth inhibitory effect of gambogic acid on pancreatic cancer cells
      354. The natural compound gambogic acid radiosensitizes nasopharyngeal carcinoma cells under hypoxic conditions
      355. The natural interaction between gambogic acid and oxaliplatin and its probably mechanism
      356. The NF-kappa B inhibitor, celastrol, could enhance the anti-cancer effect of gambogic acid on oral squamous cell carcinoma
      357. The Noncompetitive Effect of gambogic acid Displaces Fluorescence-Labeled ATP but Requires ATP for Binding to Hsp90/HtpG
      358. The nuclear export of TR3 mediated gambogic acid-induced apoptosis in cervical cancer cells through mitochondrial dysfunction
      359. The regulation of neo-gambogic acid on miRNAs for epithelial-mesenchymal transition and drug-resistance of cervical cancer
      360. THERAPEUTIC POTENCIAL OF gambogic acid AND SILIBININ IN ACUTE MYELOBLASTIC LEUKEMIA-IN VITRO STUDIES: PB1708
      361. Therapeutic Potential of gambogic acid and Silibinin in Acute Myeloblastic Leukemia–in vitro studies
      362. Therapeutic potential of gambogic acid, a caged xanthone, to target cancer
      363. Titania-coated gold nanorods as an effective carrier for gambogic acid
      364. Toxicological studies of gambogic acid and its potential targets in experimental animals
      365. Transcriptional Analysis of the Effects of gambogic acid and Neogambogic acid: Inhibition of Staphylococcus aureus and methicillin-resistant Staphylococcus aureus
      366. Triphenylphosphonium-modified poly (ethylene glycol)-poly (ε-caprolactone) micelles for mitochondria-targeted gambogic acid delivery
      367. Tumor neovasculature-targeted cationic PEGylated liposomes of gambogic acid for the treatment of triple-negative breast cancer
      368. UHPLC‐MS method for determination of gambogic acid and application to bioavailability, pharmacokinetics, excretion and tissue distribution in rats
      369. UNC119 mediates gambogic acid-induced cell-cycle dysregulation through the Gsk3β/β-catenin pathway in hepatocellular carcinoma cells
      370. Viability inhibition effect of gambogic acid combined with cisplatin on osteosarcoma cells via mitochondria-independent apoptotic pathway
      371. Water-soluble gambogic acid PEGylated prodrugs: synthesis, characterization, physicochemical properties and in vitro hydrolysis
      372. α-Mangostin and gambogic acid as potential inhibitors of the p53–MDM2 interaction revealed by a yeast approach
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