HMGB1
January 30, 2020ALZHEIMERโS, DEMENTIA, PARKINSONโS
February 2, 2020
- 12P Individualized Breast Cancer Therapy Using Mcl-1 Inhibition Based Combination
- 155: Trem-1 Protects Monocyte From Apoptosis Via Mcl-1-Dependent Mechanism
- 1-Phenyl-1H-Indole Derivatives As A New Class Of Bcl-2/Mcl-1 Dual Inhibitors: Design, Synthesis, And Preliminary Biological Evaluation
- 2-Deoxyglucose Pretreatment Sensitizes Colon Cancer Cells To Cisplatin And Killer Trail Induced Apoptosis By Mcl-1 Downregulation
- 3656: Apoptosis In Human Cancer Cells In A Bcl-Xl, Bcl2 And Mcl-1 โฆ
- 3-Bromopyruvate Induces Apoptosis In Breast Cancer Cells By Downregulating Mcl-1 Through The Pi3K/Akt Signaling Pathway
- 3-Substituted-N-(4-Hydroxynaphthalen-1-Yl)Arylsulfonamides As A Novel Class Of Selective Mcl-1 Inhibitors: Structure-Based Design, Synthesis, Sar, And Biological โฆ
- 3-Thiomorpholin-8-Oxo-8H-Acenaphtho [1, 2-B] Pyrrole-9-Carbonitrile (S1) Derivatives As Pan-Bcl-2-Inhibitors Of Bcl-2, Bcl-Xl And Mcl-1
- 5-Fluorouracil Induction Of Fas And Apoptosis In Colon Cancer Patients: Relation Of Clinical Outcome With Thymidylate Synthase, Mcl-1 And Rb
- 7-Isopenthenyloxycoumarin, Arctigenin, And Hesperidin Modify Myeloid Cell Leukemia Type-1 (Mcl-1) Gene Expression By Hormesis In K562 Cell Line
- A Chemotherapy-Driven Increase In Mcl-1 Mediates The Effect Of Mir-375 On Cisplatin Resistance In Osteosarcoma Cells.
- A Competitive Stapled Peptide Screen Identifies A Selective Small Molecule That Overcomes Mcl-1-Dependent Leukemia Cell Survival
- A Critical Epithelial Survival Axis Regulated By Mcl-1 Maintains Thymic Function
- A Critical Epithelial Survival Axis Regulated By Mcl-1 Maintains Thymic Function In Mice
- A Inhibits Sodium Nitroprusside-Induced Cardiac H9C2 Cell Death Through Suppressing Activation Of Jnk And Preserving Mitochondrial Anti-Apoptotic Bcl-2 And Mcl-1
- A Kinase Inhibitor Screen Identifies Mcl-1 And Aurora Kinase A As Novel Treatment Targets In Antiestrogen-Resistant Breast Cancer Cells
- A Luciferase-Based Assay Identifies Niclosamide Derivatives Antagonizing Mcl-1 Through Post-Translational Down-Regulation
- A Major Role For Mcl-1 Antiapoptotic Protein In The Il-6-Induced Survival Of Human Myeloma Cells
- A Non-Apoptotic Function For Mcl-1 As An Activator Of Canonical Wnt Signaling In Keratinocytes
- A Non-Apoptotic Function Of Mcl-1 In Promoting Pluripotency And Modulating Mitochondrial Dynamics In Stem Cells
- A Novel Allosteric Mechanism For Molecular Inhibition Of Anti-Apoptotic Mcl-1
- A Novel Atp-Competitive Mek/Aurora Kinase Inhibitor Bi-847325 Reverses Acquired Braf Inhibitor Resistance Through Suppression Of Mcl-1 And Inhibition Of Mek โฆ
- A Novel Bh 3 Mimetic Efficiently Induces Apoptosis In Melanoma Cells Through Direct Binding To AntiโApoptotic Bclโ2 Family Proteins, Including Phosphorylated Mclโ1
- A Novel Bh3 Ligand That Selectively Targets Mcl-1 Reveals That Apoptosis Can Proceed Without Mcl-1 Degradation
- A Novel Bh3 Mimetic S1 Potently Induces Bax/BakโDependent Apoptosis By Targeting Both Bclโ2 And Mclโ1
- A Novel Biomarker Approach In Mcl-1 Dependent Relapsed/Refractory Aml
- A Novel Histone Deacetylase Inhibitor, Cg200745, Potentiates Anticancer Effect Of Docetaxel In Prostate Cancer Via Decreasing Mcl-1 And Bcl-Xl
- A Novel Pan Inhibitor Of Bcl-2 And Mcl-1 Apogossypolone (Apog2) With Superior Stability And Improved Activity Against Human Leukemia And Lymphoma Cells.
- A Novel Selective Mcl-1 Inhibitor Exhibits In Vitro And In Vivo Efficacy In Melanoma
- A Novel Small Molecule Fl118 That Selectively Inhibits Survivin, Mcl-1, Xiap And Ciap2 In A P53-Independent Manner, Shows Superior Antitumor Activity
- A Novel Small-Molecule Iap Antagonist, Azd5582, Draws Mcl-1 Down-Regulation For Induction Of Apoptosis Through Targeting Of Ciap1 And Xiap In Human โฆ
- A Novel Small-Molecule Inhibitor Of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro And In Vivo
- A Noxa/Mclโ1 Imbalance Underlies Chemoresistance Of Malignant Rhabdoid Tumor Cells
- A Phase 1, First-In-Human Study Of Amg 176, A Selective Mcl-1 Inhibitor, In Patients With Relapsed Or Refractory Multiple Myeloma
- A Pivotal Role For Mcl-1 In Bortezomib-Induced Apoptosis
- A Proteolytic Fragment Of Mcl-1 Exhibits Nuclear Localization And Regulates Cell Growth By Interaction With Cdk1
- A Same Day Assay Using Cytochrome C Release Determines Sensitivity To Cooperative Bcl-2 And Mcl-1 Targeting In Multiple โฆ
- A Short Term Biomarker-Based Assay Predicts Apoptotic Response To Combined Bcl-2/Mcl-1 Bh3 Mimetic Targeting In Myeloma Cells
- A Small Molecule Cyclin Dependent Kinase Inhibitor, Overcomes Drug Resistance Via Down-Regulation Of Mcl-1 In Multiple Myeloma (Mm)
- A Stapled Bim Bh3 Helix Overcomes The Mcl-1-Mediated Apoptotic Blockade Of Refractory Hematologic Cancers
- A Study Of Myc And Mcl-1 Transcript Levels Before And During Tyrosine Kinase Inhibitor Therapy In Chronic Myeloid Leukemia Patients
- A Subset Of Small Cell Lung Cancer (Sclc) Cell Lines Are Mcl-1-Dependent And Undergo Apoptosis In Response To Flavopiridol-Mediated Inhibition Of Cyclin-Dependent โฆ
- A Subset Of Small Cell Lung Cancer (Sclc) Cell Lines Is Mcl-1-Dependent And Responds To Cyclin-Dependent Kinase (Cdk) 9 Inhibition In Vitro And In Vivo
- A Subunit Of The Mammalian Oligosaccharyltransferase, Dadi, Interacts With Mcl-1, One Of The Bcl-2 Protein Family
- Aโ1210477, A Selective Mclโ1 Inhibitor, Overcomes Abtโ737 Resistance In Aml
- Absence Of Macrophage Mcl-1 Induces Foam Cell Formation And Atherosclerotic Plaque Apoptosis Without Affecting Plaque Development In Ldlrโ/โ Mice
- Abstract A021: Genipin Enhanced Apoptosis Of Gastric Cancer By Mitochondrial Dysfunction And Downregulation Of Stat3/Jak2/Mcl-1 Signaling Pathway
- Abstract A23: Noxa Determines Localization And Stability Of Mcl-1 And Consequently Abt-737 Sensitivity In Small Cell Lung Cancer.
- Abstract A60: Mcl-1 Confers Protection Of Her2-Positive Breast Cancer Cells To Hypoxia: Therapeutic Implications
- Abstract A65: A Novel Small-Molecule Iap Antagonist, Azd5582, Draws Mcl-1 Down-Regulation For Induction Of Apoptosis Through Targeting Of Ciap1 And Xiap In Human โฆ
- Abstract A65: Combinational Sirna Silencing Of Mcl-1 And P-Gp Enhances The Apoptotic Response In Human Breast Cancer Cells
- Abstract B07: Mcl-1-Mediated Resistance To Abt-263 Is Combated By Mtor Inhibition In Luminal Breast Cancers
- Abstract B071: Targeting The Antiapoptotic Protein Mcl-1 In Luminal B Breast Cancers
- Abstract B09: Mcl-1 Inhibition Improves Abt199 Efficacy For Bcl-2-Dependent Neuroblastoma
- Abstract B09: Targeting The Anti-Apoptotic Protein Mcl-1 With The Mtor Inhibitor Rad001 Sensitizes Luminal Breast Cancers To The Bcl-2/Bcl-Xl Inhibitor Abt-263
- Abstract B17: Synergism Between P53 And Mcl-1 In Hepatocyte Maturation And Survival
- Abstract B26: Targeting Glucose And Glutamine Metabolism In Melanoma Cells Influences Noxa And Mclโ1 Levels As Well As Susceptibility To TrailโInduced Apoptosis
- Abstract B76: Targeting Mcl-1 For Radiosensitization Of Pancreatic Cancers
- Abstract B89: The Effects Of Raf Kinase Inhibition With Either Sorafenib Or Plxโ4720 On Mclโ1 Expression And Cytotoxicity Alone And In Combination With Abtโ737 In โฆ
- Abstract C212: Discovery Of High Affinity Cyclic Peptidomimetics Binding Mcl-1 And Ras.
- Abstract C263: Mtor Inhibition Specifically Sensitizes Colorectal Cancers With Kras Or Braf Mutations To Bcl-2/Bcl-Xl Inhibition By Suppressing Mcl-1.
- Abstract C40: Inhibition Of Mcl-1 Through Covalent Modification Of A Non-Catalytic Lysine Side Chain
- Abstract C41: Targeting The Antiapoptotic Protein Mcl-1 In Glioblastoma Multiforme
- Abstract C48: Dual Targeting Of Myeloma Cells By 2-Deoxy-D-Glucose And Abt-199 Combination Respectively Through The Down-Regulation Of Mcl-1 And Binding To Bcl-2 โฆ
- Abstract C75: Overcoming Kras/Lkb1 Mutant Nsclc Resistance To Bet Bromodomain Inhibitors With Gemcitabine Or Mcl-1 Inhibition
- Abstract Cn04-02: Discovery Of Mcl-1 Inhibitors Using Fragment-Based Methods.
- Abstract Ddt01-01: The Discovery And Preclinical Characterization Of Amg 176: A First-In-Class Mcl-1 Inhibitor In Clinical Development For Multiple Myeloma
- Abstract Ddt01-02: Azd5991: A Potent And Selective Macrocyclic Inhibitor Of Mcl-1 For Treatment Of Hematologic Cancers
- Abstract Ia02: Mcl-1 Inhibitors For The Treatment Of Cancer
- Abstract Lb-212: Mcl-1 And Fbw7 Control A Dominant Survival Pathway Underlying Hdac And Bcl-2 Inhibitor Synergy In Squamous Cell Carcinoma.
- Abstract Lb-72: An Immunoassay Detecting Bcl-2: Bim And Mcl-1: Bim Complexes In The Phase 1 Monotherapy Study Of The Bcl-2 Inhibitor, Abt-199/Gdc-0199, In โฆ
- Abstract Lb-79: Synergistic Anticancer Effects Of The 9.2. 27Pe Immunotoxin And Abt-737 In Melanoma Involves Silencing Of The Anti-Apoptotic Protein Mcl-1
- Abstract P042: Loss Of Mcl-1 In The Heart Leads To Rapid Mitochondrial Dysfunction And Development Of Heart Failure
- Abstract P43: A Distinct Region Of Mcl-1 Defines Its Antisenescent Properties
- Abstract Sy16-02: The Discovery Of Mcl-1 Inhibitors Using Fragment-Based Methods And Structure-Based Design
- Abstract# 1801: Sns-032 Reduced The Expression Of Cyclin D1 And Mcl-1 And Inhibited Survival In Mantle Cell Lymphoma Cell Lines
- Abstract# 1815: Homoharringtonine Down-Regulates Mcl-1 And Induces Apoptosis In Chronic Lymphocytic Leukemia Cells
- Abstract# 3272: Regulation Of Mcl-1 And Its Contribution To Cell Survival And Drug Resistance In Breast Cancer
- Abstract# 3275: Up-Regulation Of Mcl-1 Via Xbp1-Mediated Activation Of Akt Is Critical For Survival Of Melanoma Cells Upon Er Stress
- Abstract# 3276: The Bh3 Mimetic Obatoclax (Gx15-070) Sensitized B-Nhl Cells To Trail-Mediated Apoptosis By Activating Bak And Inhibiting Mcl-1, Nf-\# 954; B And โฆ
- Abstract# 3284: Nicotine Enhances The Antiapoptotic Function Of Mcl-1 Through Phosphorylation
- Abstract# 3693: Sorafenib Inhibits Stat3-Regulated Expression Of Prosurvival Mcl-1 And Bcl-Xl Proteins To Enhance Trail-Mediated Apoptosis In Human Pancreatic โฆ
- Abstract# 3867: Degradation Of The Anti-Apoptotic Protein Mcl-1 Correlates With Mitotic Cell Death In Response To The Novel Ksp Inhibitor Arry-520.
- Abstract# 4601: Phosphorylation And Degradation Of Mcl-1 In Vinblastine-Induced Apoptosis
- Accumulation Of The Pro-Apoptotic Factor Bak Is Controlled By Antagonist Factor Mcl-1 Availability
- Acoustic Overstimulation Modifies Mclโ1 Expression In Cochlear Sensory Epithelial Cells
- Acquired Activation Of The Akt/Cyclooxygenase-2/Mcl-1 Pathway Renders Lung Cancer Cells Resistant To Apoptosis
- Acquired Apoptosis Resistance Mediated By Activation Of The Akt/Cox-2/Mcl-1 Pathway In Lung Cancer Cells
- Acquired Resistance To Abt-737 In Lymphoma Cells That Up-Regulate Mcl-1 And Bfl-1
- Actinidia Arguta (Hardy Kiwi) Root Extract Exerts Anti-Cancer Effects Via Mcl-1-Mediated Apoptosis In Cholangiocarcinoma
- Actinomycin D Decreases Mcl-1 Expression And Acts Synergistically With Abt-737 Against Small Cell Lung Cancer Cell Lines
- Actinomycin D Synergistically Enhances The Efficacy Of The Bh3 Mimetic Abt-737 By Downregulating Mcl-1 Expression
- Activating Transcription Factor-6 (Atf6) Mediates Apoptosis With Reduction Of Myeloid Cell Leukemia Sequence 1 (Mcl-1) Protein Via Induction Of Ww Domain Binding โฆ
- Activation By Fmlp Regulates Foxo (Forkhead) Transcription Factors By Multiple Pathways, One Of Which Includes The Binding Of Foxo To The Survival Factor Mclโ1
- Activation Of Atf4 Mediates Unwanted Mcl-1 Accumulation By Proteasome Inhibition
- Activation Of The Camp Signaling Pathway Increases Apoptosis In Human BโPrecursor Cells And Is Associated With Downregulation Of Mclโ1 Expression
- Activation Of The Camp Signaling Pathway Induces Apoptosis In Human B-Precursor Cells And Is Associated With Downregulation Of Mcl-1 Expression
- Activity Of Bortezomib Against Multiple Myeloma (Mm) Through Inhibition Of Interleukin (Il)-6 Signaling: A Role For Repression Of Myeloid Cell Leukemia (Mcl)-1.
- Activity Of The Selective Bcl-2 Inhibitor Abt-199 In Childhood B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By Mcl-1/Bcl-2 Expression Serving โฆ
- Acute Myeloid Leukemia Possessing Jumping Translocation Is Related To Highly Elevated Levels Of Eat/Mcl-1, A Bcl-2 Related Gene With Anti-Apoptotic Functions
- Adaptation To Er Stress As A Driver Of Increased Expression Of Mcl-1 With Melanoma Progression
- Adenovirus-Mediated Short Hairpin Rna (Shrna) Suppresses Mcl-1 Expression Enhancing Apoptosis Sensitivity In Gastric Cancer Cells.
- Adenovirus-Mediated Sirna Targeting Mcl-1 Gene Increases Radiosensitivity Of Pancreatic Carcinoma Cells In Vitro And In Vivo
- Adsorption Of 1, 2, 3-Trichloropropane (Tcp) To Meet A Mcl Of 5 Ppt
- Afatinib Down-Regulates Mcl-1 Expression Through The Perk-Eif2ฮ-Atf4 Axis And Leads To Apoptosis In Head And Neck Squamous Cell Carcinoma
- Affinities Of Mcl-1 And Bcl-Xl For Bh3-Only Proteins Define Distinct Survival Functions At The Outer Mitochondrial Membrane Of Multiple Myeloma Cells.
- Age-Related Changes In The Ratio Of Mcl-1/Bax Expression In The Rat Cochlea
- Aggravates Cardiac Apoptosis In L-Name-Induced Pressure Overload Model In Rats: Immunohistochemical Determination Of Cardiac Caspase-3, Mcl-1, Bax And Bcl-2
- Akt-Dependent Glucose Metabolism Promotes Mcl-1 Synthesis To Maintain Cell Survival And Resistance To Bcl-2 Inhibition
- Akt-Mediated Eminent Expression Of C-Flip And Mcl-1 Confers Acquired Resistance To Trail-Induced Cytotoxicity To Lung Cancer Cells
- AlcoholโMediated Missplicing Of Mclโ1 PreโMrna Is Involved In Neurotoxicity
- Alkaloids From Piper Nigrum Synergistically Enhanced The Effect Of Paclitaxel Against Paclitaxel-Resistant Cervical Cancer Cells Through The Downregulation Of Mcl-1
- Allosteric Inhibition Of Antiapoptotic Mcl-1
- Alpha2Beta1 Integrin Promotes T Cell Survival And Migration Through The Concomitant Activation Of Erk/Mcl-1 And P38 Mapk Pathways
- Alterations In The Noxa/Mcl-1 Axis Determine Sensitivity Of Small Cell Lung Cancer To The Bh3 Mimetic Abt-737
- Alvocidib Potentiates The Activity Of Azacytidine In An Mcl-1-Dependent Fashion
- Alvocidib Potentiates The Activity Of Cytarabine And Mitoxantrone Through The Targeting Of Mcl-1 When Administered In A Time Sequential Regimen In Aml
- Amg-176, An Mcl-1 Antagonist, Shows Preclinical Efficacy In Chronic Lymphocytic Leukemia
- Aml Sensitivity To Ym155 Is Modulated Through Akt And Mcl-1
- AmpโActivated Protein Kinase (Ampk)โInduced Preconditioning In Primary Cortical Neurons Involves Activation Of Mclโ1
- Ampk-Mediated Up-Regulation Of Mtorc2 And Mcl-1 Compromises The Anti-Cancer Effects Of Aspirin
- An Essential Role For Mcl-1 In Atr-Mediated Chk1 Phosphorylation
- An Internal Eeld Domain Facilitates Mitochondrial Targeting Of Mcl-1 Via
- An Internal Eeld Domain Facilitates Mitochondrial Targeting Of Mcl-1 Via A Tom70-Dependent Pathway
- An Intravenous (Iv) Route-Compatible Formulation Of Fl118, A Survivin, Mcl-1, Xiap, And Ciap2 Selective Inhibitor, Improves Fl118 Antitumor Efficacy And โฆ
- An Rna Interference Screen Reveals A Critical Role For Mcl-1 In Survival Of Cml Progenitor Cells.
- Anacardic Acids From Knema Hookeriana As Modulators Of Bcl-Xl/Bak And Mcl-1/Bid Interactions
- Analysis Of Antioxidant Enzymes Combined With The Detection Of Mcl-1 And Bax Expressions In Acute Childhood Leukemias
- Analysis Of Flexibility And Hotspots In Bcl-Xl And Mcl-1 Proteins For The Design Of Selective Small-Molecule Inhibitors
- Analyzing The Therapeutic Efficacy Of Navitoclax And Mcl-1 Inhibitors In Juvenile Myelomonyctic Leukemia
- And Cysteamine Supplementation During In Vitro Production Of Buffalo (Bubalus Bubalis) Embryos Affect Mrna Expression Of Bclโ2, BclโXl, Mclโ1, Bax And Bid
- And Metastatic Potential In Preclinical Models Of Osteosarcoma Through A Mechanism Potentially Involving The Inhibition Of Erk1/2, Mcl-1 And Ezrin Pathways
- And Sphingosine Kinase Inhibitor Interact Synergistically To Induces Apoptosis In Bcr/Abl+ Cells Sensitive And Resistant To Sti571 Through Down-Regulation Mcl-1
- And Validation Of Mitochondria-Based Functional Assays To Investigate The Mechanism Of Small-Molecule Inhibitors Of Bcl-2/Bcl-Xl/Mcl-1 (Bh3 Mimetics) In Cell-Free โฆ
- And Viscum Album Agglutinin-I-Induced Human Neutrophil Apoptosis: Viscum Album Agglutinin-I Accelerates The Loss Of Antiapoptotic Mcl-1 Expression And The โฆ
- Androgenic Regulation Of The Anti-Apoptotic Bcl-2 Family Member Mcl-1 In Prostate Cancer Cells.
- Anisomycin Treatment Enhances Trail-Mediated Apoptosis In Renal Carcinoma Cells Through The Down-Regulation Of Bcl-2, C-Flip (L) And Mcl-1
- Annonaceous Acetogenin Mimic Aa005 Suppresses Human Colon Cancer Cell Growth In Vivo Through Downregulation Of Mcl-1
- Anoikis, Initiated By Mcl-1 Degradation And Bim Induction, Is Deregulated During Oncogenesis
- Antagonism Between Mcl-1 And Puma Governs Stem/Progenitor Cell Survival During Hematopoietic Recovery From Stress
- Anti-Apoptosis Proteins Mcl-1 And Bcl-Xl Have Different P53-Binding Profiles
- Antiapoptotic Action Of 1, 25-Dihydroxyvitamin D3Is Associated With Increased Mitochondrial Mcl-1 And Raf-1 Proteins And Reduced Release Of Cytochrome C
- Anti-Apoptotic Activity And Proteasome-Mediated Degradation Of Xenopus Mcl-1 Protein In Egg Extracts
- Anti-Apoptotic Bcl-2 Family Member Mcl-1 Regulates Cell Viability And Bone-Resorbing Activity Of Osteoclasts
- Anti-Apoptotic Bcl-X L But Not Mcl-1 Contributes To Protection Against Virus-Induced Apoptosis
- Antiapoptotic Effect Of C-Jun N-Terminal Kinase-1 Through Mcl-1 Stabilization In Tnf-Induced Hepatocyte Apoptosis
- Anti-Apoptotic Effects Of Osteopontin Through The Up-Regulation Of Mcl-1 In Gastrointestinal Stromal Tumors
- Anti-Apoptotic Functions Of Bcl-W, Mcl-1, And A1 In Mitotic Cell Death
- Antiapoptotic Mcl-1 Is Critical For The Survival And Niche-Filling Capacity Of Foxp3+ Regulatory T Cells
- Anti-Apoptotic Mcl-1 Is Essential For The Development And Sustained Growth Of Acute Myeloid Leukemia
- Anti-Apoptotic Mcl-1 Localizes To The Mitochondrial Matrix And Couples Mitochondrial Fusion To Respiration
- Anti-Apoptotic Mcl-1 Plays A Critical Role In Maintenance Of Normal And Malignant Human Hematopoietic Stem Cells Through Flt3 Signaling.
- Anti-Apoptotic Proteins Bcl-2, Mcl-1 And A1 Summate Collectively To Maintain Survival Of Immune Cell Populations Both In Vitro And In Vivo
- Antiapoptotic Proteins Mcl-1 And Bcl-2 As Well As Growth Factors Fgf And Vegf Influence Survival Of Peripheral Blood And Bone Marrow Chronic โฆ
- Antibody Fragments Structurally Enable A Drug-Discovery Campaign On The Cancer Target Mcl-1
- Anticancer Activity Of Curcumin On Human Breast Adenocarcinoma: Role Of Mcl-1 Gene
- Anticancer Bioactive Peptides Suppress Human Colorectal Tumor Cell Growth And Induce Apoptosis Via Modulating The Parp-P53-Mcl-1 Signaling Pathway
- Anti-E6/E7/Mcl-1 Pegylated Lipoplexes For A Vaginal Treatment Of Cervical Cancer
- Antigen-Affinity Controls Pre-Germinal Center B Cell Selection By Promoting Mcl-1 Induction Through Baff Receptor Signaling
- Anti-Myeloma Effect Of Homoharringtonine With Concomitant Targeting Of The Myeloma-Promoting Molecules, Mcl-1, Xiap, And ฮ-Catenin
- Antimyeloma Effect Of The Simultaneous Inhibition Of Mcl-1 (With S63845) And Bcl-2 (With Venetoclax) In The Presence Of The Microenvironment
- Antioxidant Inhibition Of Gsk-3ฮ Stabilizes Anti-Apoptotic Factor Mcl-1 Leading To Decreased Apoptosis And Increased Cell Survival.
- Antisense Oligonucleotides Against Mcl-1 Result In Increased Apoptosis Of Human Neutrophils
- Antisense Strategy Shows That Mcl-1 Rather Than Bcl-2 Or Bcl-Xl Is An Essential Survival Protein Of Human Myeloma Cells
- Antisense Targeting Of Mcl-1 Has Therapeutic Potential In Gastric Cancer
- Anti-Survival And Pro-Apoptotic Effects On Hacat Human Keratinocytes Via Caspase-And Pkc-Dependent Downregulation Of Pkb, Hiap-1, Mcl-1, Xiap And Er โฆ
- Anti-Tubulin Antibody Drug Conjugates Potentiate Venetoclax Activity In Non-Hodgkin Lymphoma By Targeting Mcl-1
- Antitumor Activity Of Fl118, A Survivin, Mcl-1, Xiap, And Ciap2 Selective Inhibitor, Is Highly Dependent On Its Primary Structure And Steric Configuration
- Apigenin Induces Apoptosis By Suppressing Bcl-Xl And Mcl-1 Simultaneously Via Signal Transducer And Activator Of Transcription 3 Signaling In Colon Cancer
- Apog2 Inhibits The Antiapoptotic Protein, Mclโ1, And Induces MitochondriaโDependent Apoptosis In Human Colorectal Cancer Cells
- Apogossypol Derivative Bi-97C1 (Sabutoclax) Targeting Mcl-1 Sensitizes Prostate Cancer Cells To Mda-7/Il-24โMediated Toxicity
- Apoptosis And Bax, Bcl-2, Mcl-1 Expression In Neutrophils Of Crohn’S Disease Patients
- Apoptosis And Expression Of Apoptosis Regulating Proteins Bcl-2, Mcl-1, Bcl-X, And Bax In Malignant Mesothelioma
- Apoptosis By Il-2 Deprivation In Human Cd8+ T Cell Blasts Predominates Over Death Receptor Ligation, Requires Bim Expression And Is Associated With Mcl-1 Loss
- Apoptosis In Gallbladder Carcinomas And Dysplasias, Its Relation To The Expression Of Caspases 3, 6 And 8 And Apoptosis Regulating Proteins Bcl-2, Mcl-1 And Bax
- Apoptosis In P53 Protein-Deficient Cells Is Mediated By Bh3-Only Protein-Independent Derepression Of Bak Protein Through Down-Regulation Of Mcl-1 And Bcl-Xl โฆ
- Apoptosis Induced By 9, 11โDehydroergosterol Peroxide From Ganoderma Lucidum Mycelium In Human Malignant Melanoma Cells Is Mclโ1 Dependent
- Apoptosis Induced By Ginkgo Biloba (Egb761) In Melanoma Cells Is Mcl-1-Dependent
- Apoptosis Induced By Overall Metabolic Stress Converges On The Bcl-2 Family Proteins Noxa And Mcl-1
- Apoptosis Induced By The Kinase Inhibitor Bay 43-9006 In Human Leukemia Cells Involves Down-Regulation Of Mcl-1 Through Inhibition Of Translation
- Apoptosis Induction In Human Melanoma Cells By Inhibition Of Mek Is Caspase-Independent And Mediated By The Bcl-2 Family Members Puma, Bim, And Mcl-1
- Apoptosis Involving The Inhibition Of Rna Polymerase Ii Carboxyl-Terminal Domain Phosphorylation And The Loss Of The Anti-Apoptotic Bcl2 Family Member Mcl-1.
- Apoptosis Is Rapidly Triggered By Antisense Depletion Of Mcl-1 In Differentiating U937 Cells
- Apoptosis Protection By Mcl-1 And Bcl-2 Modulation Of Inositol 1, 4, 5-Trisphosphate Receptor-Dependent Ca2+ Signaling
- Apoptosis Threshold Set By Noxa And Mcl-1 After T Cell Activation Regulates Competitive Selection Of High-Affinity Clones
- Apoptosis Threshold Set By Noxa And Mcl-1 Regulates Competitive Selection Of T Cell Clones
- Apoptosis Through Regulation Of Bcl-2, Bax And Mcl-1 Expressions In Endometriotic Cyst Lesions And The Endometrium Of Women With Moderate To Severe Endometriosis
- Apoptotic Effect Of Galbanic Acid Via Activation Of Caspases And Inhibition Of Mclโ1 In H460 NonโSmall Lung Carcinoma Cells
- Apoptotic Index And Apoptosis Influencing Proteins Bclโ2, Mclโ1, Bax And Caspases 3, 6 And 8 In Pancreatic Carcinoma
- Apoptotic Regulation By Mcl-1 Through Heterodimerization
- Apoptotic Resistance Of Human Skin Mast Cells Is Mediated By Mcl-1
- Arsenic In The Shallow Ground Waters Of Conterminous United States: Assessment, Health Risks, And Costs For Mcl Compliance1
- Arsenic Trioxide Plus Abt-737 Is Synergistic To Induce Apoptosis In Aml Cells By Repression Of Mcl-1 Protein And Inactivation Of Bcl-2 Protein
- Arylazopyrazole Aap 1742 Inhibits Cdk S And Induces Apoptosis In Multiple Myeloma Cells Via Mclโ1 Downregulation
- Aspirin Induces Apoptosis In Human Leukemia Cells Independently Of Nf-ฮb And Mapks Through Alteration Of The Mcl-1/Noxa Balance
- Aspirin Induces Apoptosis In Human Leukemia Cells Independently Of Nf-ฮb And Mapks Through Alteration Of The Mcl-1/Noxa Balance.
- Aspirin Induces Apoptosis In Yd-8 Human Oral Squamous Carcinoma Cells Through Activation Of Caspases, Down-Regulation Of Mcl-1, And Inactivation Of Erk-1/2 And โฆ
- Aspirin Overcomes Navitoclax-Resistance In Hepatocellular Carcinoma Cells Through Suppression Of Mcl-1
- Assessment Of Bcl-2, Bcl-Xl And Mcl-1 In Bone Marrow Biopsy Samples Using Ventana Benchmark Xt Automated Slide Stainer
- Association Of Expression Of Mcl-1 And Puma Gene In Cervical Carcinomas [J]
- Association Of High-Level Mcl-1 Expression With In Vitro And In Vivo Prednisone Resistance In Mll-Rearranged Infant Acute Lymphoblastic Leukemia
- At-101 (-/-Gossypol) In Combination With Trastuzumab Triggers Apoptosis Through Inhibiting Bcl-2, Bcl-Xl And Mcl-1 Protein Levels In โฆ
- Atโ101 Downregulates Bcl 2 And Mcl 1 And Potentiates The Cytotoxic Effects Of Lenalidomide And Dexamethasone In Preclinical Models Of Multiple Myeloma And W โฆ
- At-101 Induces Apoptosis In Cll B Cells And Overcomes Stromal CellโMediated Mcl-1 Induction And Drug Resistance
- Atm-Dependent Expression Of Iex-1 Controls Nuclear Accumulation Of Mcl-1 And The Dna Damage Response
- Attacking Oncogene Addiction In B-Cll: Seliciclib First Engages The Mcl-1/Noxa Axis, After Which Gradual Exhaustion Of Bcl-2 Protection Leads To Bax Activation.
- Atypical Apc/CโDependent Degradation Of Mclโ1 Provides An Apoptotic Timer During Mitotic Arrest
- Aurora A And Mcl-1: New Potential Treatment Targets In Antiestrogen-Resistant Breast Cancer
- Autophagy-Mediated Hmgb1 Release Antagonizes Apoptosis Of Gastric Cancer Cells Induced By Vincristine Via Transcriptional Regulation Of Mcl-1
- Azd4573 Is A Highly Selective Cdk9 Inhibitor That Suppresses Mcl-1 And Induces Apoptosis In Hematological Cancer Cells.
- Aฮฒ Activation Of Sgk1 And Increase In Mclโ1 Expression Protects Against AฮฒโInduced Toxicity In Pc12 Cells
- -B]Pyrrole-9-Carbonitrile (S1) Based Molecules As Potent, Dual Inhibitors Of B-Cell Lymphoma 2 (Bcl-2) And Myeloid Cell Leukemia Sequence 1 (Mcl-1): Structure-Based Design โฆ
- Bad And Mcl-1 Regulation In Prostate Cancer
- Bad Dephosphorylation And Decreased Expression Of Mcl-1 Induce Rapid Apoptosis In Prostate Cancer Cells
- Bag3 Upregulates Mcl-1 Through Downregulation Of Mir-29B To Induce Anticancer Drug Resistance In Ovarian Cancer
- Bag3โDependent Expression Of Mclโ1 Confers Resistance Of Mutant Kras Colon Cancer Cells To The Hsp90 Inhibitor Auy922
- Bag3-Dependent Expression Of Mcl-1 Confers Resistance Of Mutant Kras Colon Cancer Cells To The Hsp90 Inhibitor Auy922โ Published In โฆ
- Bag3-Mediated Mcl-1 Stabilization Contributes To Drug Resistance Via Interaction With Usp9X In Ovarian Cancer
- Baicalein, A Component Of Scutellaria Baicalensis, Induces Apoptosis By Mcl-1 Down-Regulation In Human Pancreatic Cancer Cells
- Bak And Mcl-1 Are Essential For Temozolomide Induced Cell Death In Human Glioma
- Bak Binding To Bcl-Xl And Not To Mcl-1 Is Associated With Abt-737 Sensitivity In Multiple Myeloma Cell Lines
- Barr Virus Latent Membrane Protein-1 Protects B-Cell Lymphoma From Rituximab-Induced Apoptosis Through Mir-155-Mediated Akt Activation And Up-Regulation Of Mcl-1
- Bax/Mcl-1 Balance Affects Neutrophil Survival In Intermittent Hypoxia And Obstructive Sleep Apnea: Effects Of P38Mapk And Erk1/2 Signaling
- Bax-Bak Heterodimer As A Pharmacodynamic Biomarker Of On-Target Drug Action Of Mcl-1 Inhibitors To Evaluate In-Vivo Effectiveness.
- Bay 61-3606 Sensitizes Trail-Induced Apoptosis By Downregulating Mcl-1 In Breast Cancer Cells
- Bcl-2 And Mcl-1 Expression In Chinese Hamster Ovary Cells Inhibits Intracellular Acidification And Apoptosis Induced By Staurosporine
- Bcl-2 Family Member Mcl-1 Expression Is Reduced Under Hypoxia By The E3 Ligase Fbw7 Contributing To Bnip3 Induced Cell Death In Glioma Cells
- Bcl-2 Family Members Puma, Noxa And Mcl-1, In P53 Mediated Neuronal Cell Death
- Bcl-2 Family Proteins In Breast Development And Cancer: Could Mcl-1 Targeting Overcome Therapeutic Resistance?
- Bcl-2 Is A Better Abt-737 Target Than Bcl-Xl Or Bcl-W And Only Noxa Overcomes Resistance Mediated By Mcl-1, Bfl-1, Or Bcl-B
- Bcl-2, Mcl-1 And P53 Expression Confer Sensitivity To Bcl-2 Inhibitor Abt-737 In Multiple Myeloma.
- Bcl-Xl And Mcl-1 Are Involved In Prevention Of In Vitro Apoptosis In Rat Late-Stage Erythroblasts Derived From Bone Marrow
- Bcl-Xl And Mcl-1 Are The Key Bcl-2 Family Proteins In Melanoma Cell Survival
- Bcl-Xl And Mcl-1 Are The Major Determinants Of The Apoptotic Response To Dual Pi3K And Mek Blockage
- BclโXl And Mclโ1 Constitute Pertinent Targets In Ovarian Carcinoma And Their Concomitant Inhibition Is Sufficient To Induce Apoptosis
- Bcl-Xl And Mcl-1 Upregulation By Calreticulin Promotes Apoptosis Resistance Of Fibroblast-Like Synoviocytes Via Activation Of Pi3K/Akt And Stat3 Pathways In โฆ
- Bcl-Xl/Mcl-1 Inhibition And Rarฮณ Antagonism Work Cooperatively In Human Hl60 Leukemia Cells
- Bcr Signaling Inhibitors Differ In Their Ability To Overcome Mcl-1โMediated Resistance Of Cll B Cells To Abt-199
- Bcr-Abl+ Bp-All Exhibits Heightened Sensitivity To Simultaneous Induction Of Energy And Er Stress Via Downregulation Of Mcl-1 Expression
- Beclin 1 Restrains Tumorigenesis Through Mcl-1 Destabilization In An Autophagy-Independent Reciprocal Manner
- Becn1 And Bim Interactions With Mcl-1 Determine Fludarabine Resistance In Leukemic B Cells
- Berberine Sensitizes Trail-Induced Apoptosis Through Proteasome-Mediated Downregulation Of C-Flip And Mcl-1 Proteins
- Betulinic Acid-Induced Mcl-1 Expression In Human MelanomaโMode Of Action And Functional Significance
- Bfl-1/A1 Functions, Similar To Mcl-1, As A Selective Tbid And Bak Antagonist
- Bh3 Mimetic Abt-737 Sensitizes Colorectal Cancer Cells To Ixazomib Through Mcl-1 Downregulation And Autophagy Inhibition
- Bh3 Mimetic Obatoclax (Gx15-070) Mediates Mitochondrial Stress Predominantly Via Mcl-1 Inhibition And Induces Autophagy-Dependent Necroptosis In โฆ
- Bh3โLigand Regulates Access Of Mclโ1 To Its E3 Ligase
- Bh3-Only Proteins Are Dispensable For Apoptosis Induced By Pharmacological Inhibition Of Both Mcl-1 And Bcl-X L
- Bh3-Only Proteins In Control: Specificity Regulates Mcl-1 And Bak-Mediated Apoptosis
- Bh3-Only Proteins Mcl-1 And Bim As Well As Endonuclease G Are Targeted In Spongistatin 1โInduced Apoptosis In Breast Cancer Cells
- Bh3-Only Proteins Target Bcl-Xl/Mcl-1, Not Bax/Bak, To Initiate Apoptosis
- Bicyclic Helical Peptides As Dual Inhibitors Selective For Bcl2A1 And Mcl-1 Proteins
- Bicyclic Helical Peptides As Dual Inhibitors Selective For Bcl2A1 And Mclโ1 Proteins
- Bile Acid-Induced โMinority Mompโ Promotes Esophageal Carcinogenesis While Maintaining Apoptotic Resistance Via Mcl-1
- Bile Acid-Mediated Induction Of Cyclooxygenase-2 And Mcl-1 In Hepatic Stellate Cells
- Bile Acids Inhibit Mcl-1 Protein Turnover Via An Epidermal Growth Factor Receptor/Raf-1-Dependent Mechanism
- Bim And Mcl-1 Exert Key Roles In Regulating Jak2 V617F Cell Survival
- Bim Phosphorylation Enhances Its Pro-Apoptotic Activity Through Down-Regulation Of The Interaction With Mcl-1
- Bim Upregulation By Histone Deacetylase Inhibitors Mediates Interactions With The Bcl-2 Antagonist Abt-737: Evidence For Distinct Roles For Bcl-2, Bcl-Xl, And Mcl-1
- Binding Affinity Of Pro-Apoptotic Bh3 Peptides For The Anti-Apoptotic Mcl-1 And A1 Proteins: Molecular Dynamics Simulations Of Mcl-1 And A1 In Complex With Six โฆ
- Binding Mode Of Pyridoclax To Myeloid Cell Leukemia-1 (Mcl-1) Revealed By Nuclear Magnetic Resonance Spectroscopy, Docking And Molecular Dynamics Approaches
- Binding Of Released Bim To Mcl-1 Is A Mechanism Of Intrinsic Resistance To Abt-199 Which Can Be Overcome By Combination With Daunorubicin Or Cytarabine In Aml โฆ
- Binding Of Released Bim To Mcl-1 Is Responsible For Resistance To Abt-199 Which Can Be Overcome By Combination With Daunorubicin Or Cytarabine In Acute Myeloid โฆ
- Biochemical And Functional Comparisons Of Mcl-1 And Bcl-2 Proteins: Evidence For A Novel Mechanism Of Regulating Bcl-2 Family Protein Function.
- Biphasic Onset Of Splenic Apoptosis Following Hemorrhagic Shock: Critical Implications For Bax, Bcl-2, And Mcl-1 Proteins
- Birc6 Mediates Imatinib Resistance Independently Of Mcl-1
- Bisindolylmaleimide Ix Is A Potent Inducer Of Apoptosis In Chronic Lymphocytic Leukaemic Cells And Activates Cleavage Of Mcl-1
- Blocks Tumor Growth, Angiogenesis, And Metastatic Potential In Preclinical Models Of Osteosarcoma Through The Inhibition Of Erk1/2, Mclโ1, And Ezrin Pathways
- Bone Marrow MicroenvironmentโDerived Signals Induce Mcl-1 Dependence In Multiple Myeloma
- Bone Marrow Stroma-Induced Resistance Of Chronic Lymphocytic Leukemia Cells To Arsenic Trioxide Involves Mcl-1 Upregulation And Is Overcome By Inhibiting โฆ
- Bone Marrow Stromal Cells Enforce Mcl-1 Dependence In Multiple Myeloma Through The Secretion Of A Soluble Factor
- Bortezomib Antagonizes Microtubule-Interfering Drug-Induced Apoptosis By Inhibiting G2/M Transition And Mcl-1 Degradation
- Bortezomib Sensitivity Of Acute Myeloid Leukemia Cd34+ Cells Can Be Enhanced By Targeting The Persisting Activity Of Nf-ฮb And The Accumulation Of Mcl-1
- Bortezomib Sensitizes Human Glioblastoma Cells To Induction Of Apoptosis By Type I Interferons Through Noxa Expression And Mcl-1 Cleavage
- BortezomibโInduced Apoptosis In Mature TโCell Lymphoma Cells Partially Depends On Upregulation Of Noxa And Functional Repression Of Mclโ1
- Braf/Mek Inhibitors Selectively Prime Melanoma For Mcl-1 Dependence And Sensitize To Mcl-1 Inhibition
- Brafv600E-Dependent Mcl-1 Stabilization Leads To Everolimus Resistance In Colon Cancer Cells
- Bryostatin Induces Protein Kinase C Modulation, Mcl-1 Up-Regulation And Phosphorylation Of Bcl-2 Resulting In Cellular Differentiation And Resistance To Drug-Induced โฆ
- Bufadienolide Compounds Sensitize Human Breast Cancer Cells To Trail-Induced Apoptosis Via Inhibition Of Stat3/Mcl-1 Pathway
- Bufo Gargarizans Mcl-1 Cloning And Its Prokaryotic Recombinant Protein Expression
- By Reducing Global Mrna Translation In Several Ways, 2-Deoxyglucose Lowers Mcl-1 Protein And Sensitizes Hemopoietic Tumor Cells To Bh3 Mimetic Abt737
- Bz-423 Superoxide Signals B Cell Apoptosis Via Mcl-1, Bak, And Bax
- C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukaemia Cells
- C-Abl Regulates Mcl-1 Gene Expression In Chronic Lymphocytic Leukemia Cells
- Cafestol Overcomes Abt-737 Resistance In Mcl-1-Overexpressed Renal Carcinoma Caki Cells Through Downregulation Of Mcl-1 Expression And Upregulation Of โฆ
- Caffeine Inhibits PaclitaxelโInduced Apoptosis In Colorectal Cancer Cells Through The Upregulation Of Mclโ1 Levels
- Caki Cells To Trail-Induced Apoptosis Through Reactive Oxygen Species-Mediated Inhibition Of Akt Signaling And Downregulation Of Mcl-1 And C-Flip (L)
- Calcium Signals Inhibition Sensitizes Ovarian Carcinoma Cells To Anti-Bcl-Xl Strategies Through Mcl-1 Down-Regulation
- Caloric Restriction Modulates Mcl-1 Expression And Sensitizes Lymphomas To Bh3 Mimetic In Mice
- Camptothecin And Khat (Catha Edulis Forsk.) Induced Distinct Cell Death Phenotypes Involving Modulation Of C-Flipl, Mcl-1, Procaspase-8 And Mitochondrial โฆ
- Carcinoma Hep-G2 Cell Proliferation By Increasing Tnf-ฮ, Caspase-8, Caspase-3 And Bax But By Decreasing Tctp And Mcl-1 Expression In Vitro
- Cardiac Specific Deletion Of Mcl-1 Leads To Impaired Autophagy And Rapid Development Of Heart Failure
- Carfilzomib And Onx 0912 Inhibit Cell Survival And Tumor Growth Of Head And Neck Cancer And Their Activities Are Enhanced By Suppression Of Mcl-1 Or Autophagy
- Caspase Cleavage Of Mcl-1 Impairs Its Anti-Apoptotic Activity And Proteasomal Degradation In Non-Small Lung Cancer Cells
- Caspase-Dependent Mcl-1 Cleavage And Effect Of Mcl-1 Phosphorylation In Abt-737-Induced Apoptosis In Human Acute Lymphoblastic Leukemia Cell Lines
- Caspase-Dependent Post-Translational Modulation Of Mcl-1 By Abt-737 In Acute Lymphoblastic Cell Lines
- Caveolin-1 Regulates Mcl-1 Stability And Anoikis In Lung Carcinoma Cells
- Caveolin-1, Antiapoptosis Signaling, And Anchorage-Independent Cell Growth. Focus On โCaveolin-1 Regulates Mcl-1 Stability And Anoikis In Lung Carcinoma Cellsโ
- Cb-59. Bcl-2 Family Member Mcl-1 Regulates Hypoxia-Induced Cell Death Through Blocking Bh3-Only Member Bnip3 Function In โฆ
- Cbio-10Bcl-2 Family Member Mcl-1 Expression Is Reduced Under Hypoxia By The E3 Ligase Fbw7 Contributing To Bnip3 Induced Cell โฆ
- Cd44 Activation Enhances Acute Monoblastic Leukemia Cell Survival Via Mcl-1 Upregulation
- Cd44 Signaling Via Pi3K/Akt And Mapk/Erk Pathways Protects Cll Cells From Spontaneous And Drug Induced Apoptosis Through Mcl-1
- Cdk Inhibitors Roscovitine And Cr8 Trigger Mcl-1 Down-Regulation And Apoptotic Cell Death In Neuroblastoma Cells
- Cdk1/Cyclin B Plays A Key Role In Mitotic Arrest-Induced Apoptosis By Phosphorylation Of Mcl-1, Promoting Its Degradation And Freeing Bak From Sequestration
- Cdk5 Inhibitor Downregulates Mcl-1 And Sensitizes Pancreatic Cancer Cell Lines To Navitoclax
- Cdk9 Inhibition By Dinaciclib Potently Suppresses Mcl-1 To Induce Durable Apoptotic Responses In Aggressive Myc-Driven B-Cell Lymphoma In Vivo
- Cdk9 Inhibition Reverses Resistance To Abt-199 (Gdc-0199) By Down-Regulating Mcl-1
- Cdk9 Inhibitors Selectively Target Estrogen Receptor-Positive Breast Cancer Cells Through Combined Inhibition Of Myb And Mcl-1 Expression
- Cell Penetrating Proteins Targeting Mcl-1 Induce In Vitro And In Vivo On-Target Cancer Cell Killing Of Mcl-1 Dependent Cell Lines
- Cells To VorinostatโInduced Apoptosis Depends On Reactive Oxygen Species Production, Mitochondrial Dysfunction, Noxa Upregulation, Mclโ1 Cleavage, And Dna โฆ
- Ceramide Analogue Saclac Modulates Sphingolipid Levels And Mcl-1 Splicing To Induce Apoptosis In Acute Myeloid Leukemia
- C-Flip And The Noxa/Mcl-1 Axis Participate In The Synergistic Effect Of Pemetrexed Plus Cisplatin In Human Choroidal Melanoma Cells
- Changes In Mcl-1 And Bim Expression With Bortezomib And Melphalan Therapy For Multiple Myeloma.
- Changes In Mcl-1 Expression In Rectal Cancer In Relation To Neo-Adjuvant Radiotherapy
- Characterisation Of Mclโ1 Cleavage During Apoptosis Of Haematopoietic Cells
- Characterization And Development Of On-Target Mcl-1 Inhibitors; Bh3 Profiling Provides A Valuable Drug Discovery Tool.
- Characterization And Expression Analyses Of Anti-Apoptotic Bcl-2-Like Genes Nr-13, Mcl-1, Bcl-X1, And Bcl-X2 In Atlantic Cod (Gadus Morhua)
- Characterization Of Mcl-1 Isoforms And Their Impacts On Mammalian Cell Growth
- Characterization Of Pyoluteorin Derivatives As Mcl-1 Antagonists
- Characterization Of The Antiapoptotic Bcl-2 Family Member Myeloid Cell Leukemia-1 (Mcl-1) And The Stimulation Of Its Message By Gonadotropins In The Rat Ovary
- Characterizaton Of Mcl-1 In Regulating Different Forms Of Cell Death
- Chemical Perturbation Of Mcl-1 Pre-Mrna Splicing To Induce Apoptosis In Cancer Cells
- Chemotherapeutic Drugs Sensitize Human Renal Cell Carcinoma Cells To Abt-737 By A Mechanism Involving The Noxa-Dependent Inactivation Of Mcl-1 Or A1
- Chidamide Inhibits Aerobic Metabolism To Induce Pancreatic Cancer Cell Growth Arrest By Promoting Mcl-1 Degradation
- Chlamydia Trachomatis Can Protect Host Cells Against Apoptosis In The Absence Of Cellular Inhibitor Of Apoptosis Proteins And Mcl-1
- Chlamydia Trachomatis-Containing Vacuole Serves As Deubiquitination Platform To Stabilize Mcl-1 And To Interfere With Host Defense
- Chloroplumbagin Induces Cell Death In Breast Cancer Cells Through Mapk-Mediated Mcl-1 Inhibition
- Chloroquine Induces Apoptosis Of Human Hepatocellular Carcinoma Cells In Vitro By Mir-26B-Mediated Regulation Of Mcl-1
- Chop Treatment Enhances Dependency On Bcl-2, Mcl-1 And Bcl-Xl In Diffuse Large B-Cell Lymphoma: Pf521
- Chromatin Remodeling At Alu Repeats By Epigenetic Treatment Activates Silenced Microrna-512-5P With Downregulation Of Mcl-1 In Human Gastric Cancer Cells
- Chrysin Overcomes Trail Resistance Of Cancer Cells Through Mcl-1 Downregulation By Inhibiting Stat3 Phosphorylation
- Circular Rna Circ_0067934 Functions As An Oncogene In Breast Cancer By Targeting Mcl-1
- Circumvention Of Mcl-1-Dependent Drug Resistance By Simultaneous Chk1 And Mek1/2 Inhibition In Human Multiple Myeloma Cells
- Cleavage Of Mcl-1 By Caspases Impaired Its Ability To Counteract Bim-Induced Apoptosis
- Clinical Significance And Expression Of Puma, Mcl-1, And P53 In Human Renal Cell Carcinoma And Para-Carcinoma Tissues
- Clitocine Induces Apoptosis And Enhances The Lethality Of Abt-737 In Human Colon Cancer Cells By Disrupting The Interaction Of Mcl-1 And Bak
- Clitocine Potentiates Trail-Mediated Apoptosis In Human Colon Cancer Cells By Promoting Mcl-1 Degradation
- Clitocine Targets Mcl-1 To Induce Drug-Resistant Human Cancer Cell Apoptosis In Vitro And Tumor Growth Inhibition In Vivo
- Cloning And Bioinformatics Analysis Of Mcl-1 Cdna Of Bufo Japonicus Formosus [J]
- Cloning And Characterization Of Cdna Encoding The Porcine Mcl-1 Protein
- C-Myc Dependent Expression Of Pro-Apoptotic Bim Renders Her2-Overexpressing Breast Cancer Cells Dependent On Anti-Apoptotic Mcl-1
- Co-Delivery Of Gemcitabine And Mcl-1 Sirna Via Cationic Liposome-Based System Enhances The Efficacy Of Chemotherapy In Pancreatic Cancer
- Co-Inhibition Of Bcl-Xl And Mcl-1 With Bcl-2 Selective Inhibitors A1331852 And S63845 Enhances Cytotoxicity Of Cervical Cancer Cell Lines
- Colorectal Cancer Cell Lines With High Bcl-Xl And Low Mcl-1 Expression Are Sensitive To A Potent And Selective Bcl-Xl Inhibitor
- Combination Of Hypoglycemia And Metformin Impairs Tumor Metabolic Plasticity And Growth By Modulating The Pp2A-Gsk3ฮ-Mcl-1 Axis
- Combination Treatment Of Rad001 And Bez235 Exhibits Synergistic Antitumor Activity Via Down-Regulation Of P-4E-Bp1/Mcl-1 In Small Cell Lung Cancer
- Combined Inhibition Of Bcl-2 And Mcl-1 In Small Cell Lung Cancer (Sclc) Is Most Effective In Tumors With Low Bcl-Xl Expression
- Combined Inhibition Of Rac1 And Bcl-2/Bcl-Xl Synergistically Induces Glioblastoma Cell Death Through Down-Regulation Of The Usp9X/Mcl-1 Axis
- Combined Inhibition Of The Pi3K/Mtor/Mek Pathway Induces Bim/Mcl-1-Regulated Apoptosis In Pancreatic Cancer Cells
- Combined Targeting Of Mcl-1 With Tg02 And Bcl-2 With Abt-199/Abt-737 For Treatment Of Hematologic Malignancies
- Combined Targeting Of Mek And Mcl-1 Induces Apoptosis And Tumor Regression Of Kras Mutant Nsclc
- Comparison Of Umbelliprenin And Auraptene In Cytotoxic Effects And Myeloid Cell Leukemia Type-1 (Mcl-1) Gene Expression
- Compound C Sensitizes Caki Renal Cancer Cells To Trail-Induced Apoptosis Through Reactive Oxygen Species-Mediated Down-Regulation Of C-Flipl And Mcl-1
- Computer-Aided Drug Design Of Neuraminidase Inhibitors And Mcl-1 Specific Drugs
- Concomitant Targeting Of Hedgehog Signaling And Mcl-1 Synergistically Induces Cell Death In Hedgehog-Driven Cancer Cells
- Concurrent Inhibition Of Pi3K And Mtorc1/Mtorc2 Overcomes Resistance To Rapamycin Induced Apoptosis By DownโRegulation Of Mclโ1 In Mantle Cell Lymphoma
- Concurrent Inhibition Of Pi3-Kinase And Mtor Induces Cell Death In Diffuse Large B Cell Lymphomas, A Mechanism Involving Down Regulation Of Mcl-1
- Concurrent Inhibition Of Pim And Flt3 Kinases Enhances Apoptosis Of Flt3-Itd Acute Myeloid Leukemia Cells Through Increased Mcl-1 Proteasomal Degradation
- Constitutively Activated Akt-1 Is Vital For The Survival Of Human Monocyte-Differentiated Macrophages: Role Of Mcl-1, Independent Of Nuclear Factor (Nf)-ฮb, Bad, Or โฆ
- Construction Of Recombinant Plasmids Containing Shrna Targeting Mcl-1 Gene And Its Effect On Proliferation And Apoptosis Of Hepg2 Cells
- Contrasting Effects Of Nutlin-3 On Trail-And Docetaxel-Induced Apoptosis Due To Upregulation Of Trail-R2 And Mcl-1 In Human Melanoma Cells
- Cooperative Anti-Leukemic Effects Of Imatinib And Mcl-1 Antisense: Identification Of Mcl-1 As A Novel Target In Cml.
- Cooperative Regulation Of Mcl-1 By Janus Kinase/Stat And Phosphatidylinositol 3-Kinase Contribute To Granulocyte-Macrophage Colony-Stimulating Factor-Delayed โฆ
- Correction To โStructure Based Design Of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitorsโ
- Correction To: A Novel Histone Deacetylase Inhibitor, Cg200745, Potentiates Anticancer Effect Of Docetaxel In Prostate Cancer Via Decreasing Mcl-1 And Bcl-Xl.
- Correction: The Multikinase Inhibitor Sorafenib Potentiates Trail Lethality In Human Leukemia Cells In Association With Mcl-1 And Cflipl Down-Regulation
- Correlation Between Mcl-1 And Pakt Protein Expression In Colorectal Cancer
- Cover Picture: Deactivation Of Mclโ1 By DualโFunction SmallโMolecule Inhibitors Targeting The Bclโ2 Homology 3 Domain And Facilitating Mclโ1 Ubiquitination โฆ
- Coxiella Burnetii Inhibits Neutrophil Apoptosis By Exploiting Survival Pathways And Antiapoptotic Protein Mcl-1
- Critical B-Lymphoid Cell Intrinsic Role Of Endogenous Mcl-1 In C-Myc-Induced Lymphomagenesis
- Critical Contribution Of Mcl-1 In Emt-Associated Chemo-Resistance In A549 Non-Small Cell Lung Cancer
- Critical Role For Antiapoptotic Bcl-Xl And Mcl-1 In Human Macrophage Survival And Cellular Iap1/2 (Ciap1/2) In Resistance To Hiv-Vpr-Induced Apoptosis
- Critical Roles Of Noxa And Mcl-1 In The Signaling Mechanisms Of Bortezomib In Traf3-Deficient Mouse B Lymphoma And Human Multiple Myeloma Cells
- Crosstalk Among Bcl-2 Family Members In B-Cll: Seliciclib Acts Via The Mcl-1/Noxa Axis And Gradual Exhaustion Of Bcl-2 Protection
- Cryptosphaerolide, A Cytotoxic Mcl-1 Inhibitor From A Marine-Derived Ascomycete Related To The Genus Cryptosphaeria
- Culmination Of Mg132-Induced Apoptosis In Human Lung Cancer Nci-H1703 Cells Depends On A Positive Feedback Of Caspase Activation And Mcl-1 Cleavage
- Curcumin Induces Apoptosis And Inhibits Proliferation In Infantile Hemangioma Endothelial Cells Via Downregulation Of Mcl-1 And Hif-1ฮ
- Current And Emerging Therapies For Patients With Acute Myeloid Leukemia: A Focus On Mcl-1 And The Cdk9 Pathway.
- Cyc202 (R-Roscovitine) Induces Apoptosis In Multiple Myeloma Cells By Down Regulation Of Mcl-1
- Cyclic Amp Delays Neutrophil Apoptosis Via Stabilization Of Mcl-1
- Cyclic Marinopyrrole Derivatives As Disruptors Of Mcl-1 And Bcl-Xl Binding To Bim
- Cyclin E But Not Bcl-2, Bax Or Mcl-1 Is Differentially Expressed In Zap 70-Positive And Zap 70-Negative B-Cll Cells
- Cyclin E/Cdk2-Dependent Phosphorylation Of Mcl-1 Determines Its Stability And Cellular Sensitivity To Bh3 Mimetics
- Cyclin E1 Inhibition Can Overcome Sorafenib Resistance In Hepatocellular Carcinoma Cells Through Mcl-1 Suppression
- Cyclin-Dependent Kinase Inhibitor Drugs Drive Neutrophil Granulocyte Apoptosis By Transcriptional Inhibition Of The Key Survival Protein Mcl-1
- Cyclocommunol Induces Apoptosis In Human Oral Squamous Cell Carcinoma Partially Through A Mcl-1-Dependent Mechanism
- Cyclooxygenase-2 Inducing Mcl-1-Dependent Survival Mechanism In Human Lung Adenocarcinoma Cl1. 0 Cells Involvement Of Phosphatidylinositol 3 โฆ
- Cytokine-Dependent And Cytokine-Independent Roles For Mcl-1: Genetic Evidence For Multiple Mechanisms By Which Mcl-1 Promotes Survival In Primary T โฆ
- Cytotoxicity Induced By Manipulation Of Signal Transduction Pathways Is Associated With Down-Regulation Of Bcl-2 But Not Mcl-1 In Mcf-7 Human Breast Cancer
- De Novo Design, Synthesis And Evaluation Of Benzylpiperazine Derivatives As Highly Selective Binders Of Mclโ1
- Deactivation Of Mclโ1 By DualโFunction SmallโMolecule Inhibitors Targeting The Bclโ2 Homology 3 Domain And Facilitating Mclโ1 Ubiquitination
- Death Of Multiple Myeloma Cells Induced By Camp-Signaling Involves Downregulation Of Mcl-1 Via The Jak/Stat Pathway
- Decreased Mcl-1 Protein Level In The Striatum Of 1-Methyl-4-Phenyl-1, 2, 3, 6-Tetrahydropyridine (Mptp)-Treated Mice
- Degradation Of Mcl-1 By Bufalin Reverses Acquired Resistance To Osimertinib In Egfr-Mutant Lung Cancer
- Degradation Of Mcl-1 By Granzyme B Implications For Bim-Mediated Mitochondrial Apoptotic Events
- Degradation Of Mcl-1 By ฮ-Trcp Mediates Glycogen Synthase Kinase 3-Induced Tumor Suppression And Chemosensitization
- Degradation Of Mcl-1 Through Gsk-3ฮ Activation Regulates Apoptosis Induced By Bufalin In Non-Small Cell Lung Cancer H1975 Cells
- Delayed Apoptosis By Neutrophils From Copd Patients Is Associated With Altered Bak, Bcl-Xl, And Mcl-1 Mrna Expression
- Deleting Mcl-1 In Mast Cells: Getting 2 Birds With 1 Stone
- Deletion Of Mcl-1 Causes Lethal Cardiac Failure And Mitochondrial Dysfunction
- Deletion Of Mir155 Prevents Fas-Induced Liver Injury Through Up-Regulation Of Mcl-1
- Demethoxy-Reblastatin, An Hsp90 Inhibitor, Induces Mitochondria-Mediated Apoptosis Through Downregulation Of Mcl-1 In Human Hepatocellular Carcinoma Cells
- Deregulated Expression Of A1, Bcl-2, Bcl-Xl, And Mcl-1 Antiapoptotic Proteins And Bid, Bad, And Bax Proapoptotic Genes In Polycythemia Vera Patients
- Design, Synthesis And Biological Evaluation Of Two Chemical Classes As Novel Small Molecule Mcl-1 Inhibitors
- Design, Synthesis And Evaluation Of Marinopyrrole Derivatives As Selective Inhibitors Of Mcl-1 Binding To Pro-Apoptotic Bim And Dual Mcl-1/Bcl-Xl Inhibitors
- Design, Synthesis And Preliminary Bioactivity Studies Of Indomethacin Derivatives As Bcl-2/Mcl-1 Dual Inhibitors
- Design, Synthesis And Preliminary Biological Evaluation Of Indole-3-Carboxylic Acid-Based Skeleton Of Bcl-2/Mcl-1 Dual Inhibitors
- Design, Synthesis And Preliminary Biological Studies Of Pyrrolidine Derivatives As Mcl-1 Inhibitors
- Design, Synthesis And StructureโActivity Relationship Studies Of Morpholino-1H-Phenalene Derivatives That Antagonize Mcl-1/Bcl-2
- Designed Bh3 Peptides With High Affinity And Specificity For Targeting Mcl-1 In Cells
- Designing Of De Novo Dual Inhibitors For Bcl-Xl And Mcl-1 Of Bcl2-Family Proteins By Computational Methods
- Detection Of Bcl-2 In Kaposi’S Sarcoma Lesions Varies According To Histopathologic Stage, Whereas Expression Of Bcl-X And Mcl-1 Differs According To Human โฆ
- Determinants Of Bh3 Binding Specificity For Mcl-1 Versus Bcl-Xl
- Deubiquitinase Usp9X Confers Radioresistance Through Stabilization Of Mcl-1
- Deubiquitylating Enzyme Usp9X Regulates Radiosensitivity In Glioblastoma Cells By Mcl-1-Dependent And-Independent Mechanisms
- Development And Characterization Of Novel Mcl-1 Inhibitors For Treatment Of Cancer.
- Development And Maintenance Of B And T Lymphocytes Requires Antiapoptotic Mcl-1
- Development Of An Efficient Route Toward Meiogynin A-Derived Dual Inhibitors Of Bcl-Xl And Mcl-1 Anti-Apoptotic Proteins
- Development Of An Efficient Route Toward Meiogynin A-Inspired Dual Inhibitors Of Bcl-Xl And Mcl-1 Anti-Apoptotic Proteins
- Development Of Novel Dual Inhibitor Of Chemokine Receptor 4 And Mcl-1 Against Multiple Myeloma
- Development Of Small Molecule Inhibitors Of Mcl-1 For Cancer Therapy
- Dexamethasone Synergizes With Mcl-1 Inhibition In Multiple Myeloma Through Suppression Of S6 Phosphorylation
- Dicoumarol Sensitizes Renal Cell Carcinoma Caki Cells To Trail-Induced Apoptosis Through Down-Regulation Of Bcl-2, Mcl-1 And C-Flip In A Nqo1-Independent Manner
- Differences In Dna Binding Properties Between E2F1 And E2F4 Specify Repression Of The Mcl-1 Promoter
- Differences In Trail-Induced Changes Of Mcl-1 Expression Among Distinct Human Colon Epithelial Cell Lines
- Differential Binding Affinities Of Anti-Apoptotic Mcl-1 And A1 Proteins For The Pro-Apoptotic Bh3 Peptides: Understanding The Molecular Basis Using Md โฆ
- Differential Effects Of Aging On Mcl-1 And Caspase 3 Expression In Murine Small And Large Intestine
- Differential Effects Of Anti-Apoptotic Bcl-2 Family Members Mcl-1, Bcl-2, And Bcl-Xl On Celecoxib-Induced Apoptosis
- Differential Gadd45, P21C1P1/Waf1, Mcl-1 And Topoisomerase Ii Gene Induction And Secondary Dna Fragmentation After Camptothecin-Induced Dna Damage In โฆ
- Differential Mcl-1 Processing In Evasion Of Dca-Induced Apoptosis Of Colorectal Cancer Cells.
- Differential Noxa/Mcl-1 Balance In Peripheral Versus Lymph Node Chronic Lymphocytic Leukemia Cells Correlates With Survival Capacity
- Differential Regulation Of Bax And Bak By Anti-Apoptotic Bcl-2 Family Proteins Bcl-B And Mcl-1
- Differential Regulations And Roles Of Mcl-1 And Bcl-Xl During Megakaryopoiesis
- Differential Regulations And Roles Of Mcl-1 And Bcl-Xl During Megakaryopoiesis (์ด)
- Differential Responses Of Mcl-1 In Photosensitized Epithelial Vs Lymphoid-Derived Human Cancer Cells
- Dihydroartemisinin Suppresses Stat3 Signaling And Mcl-1 And Survivin Expression To Potentiate Abt-263-Induced Apoptosis In Non-Small Cell Lung Cancer Cells โฆ
- Diminishing Mcl-1 Protein Leads To Apoptosis Of Acute Myeloid Leukemia Cells Responding To All Trans Retinoic Acid Differentiation
- Dinaciclib Potently Suppresses Mcl-1 And Selectively Induces The Cell Death In Human Ips Cells Without Affecting The Viability Of Cardiac Tissue
- Dinaciclib, A Cdk Inhibitor Promotes Proteasomal Degradation Of Mcl-1 And Enhances Abt-737 Mediated Cell Death In Malignant Human Glioma Cell Lines
- Dinaciclib, A Cyclin-Dependent Kinase Inhibitor Promotes Proteasomal Degradation Of Mcl-1 And Enhances Abt-737โMediated Cell Death In Malignant Human โฆ
- Diphenhydramine Induces Melanoma Cell Apoptosis By Suppressing Stat3/Mcl-1 Survival Signaling And Retards B16-F10 Melanoma Growth In Vivo
- Direct Regulation Of Mitochondrial Fatty Acid Oxidation By Anti-Apoptotic Mcl-1
- Direct Repression Of The Mcl-1 Promoter By E2F1
- โDirected Binding For The Discovery Of Modulators Of ฮโHelixโMediated ProteinโProtein Interactions: ProofโOfโConcept Studies With The Apoptosis Regulator Mclโ1
- Discovery And Characterization Of 2, 5-Substituted Benzoic Acid Dual Inhibitors Of The Anti-Apoptotic Mcl-1 And Bfl-1 Proteins
- Discovery And Characterization Of New Small-Molecule Inhibitors Of Mcl-1 By High-Throughput Screening
- Discovery And Development Of 1, 2, 3, 4-Tetrahydroisoquinoline-3-Carboxylic Acid Derivatives As Bcl-2/Mcl-1 Inhibitors
- Discovery And Development Of Substituted Tyrosine Derivatives As Bcl-2/Mcl-1 Inhibitors
- Discovery And In Vivo Evaluation Of Macrocyclic Mcl-1 Inhibitors Featuring An ฮ-Hydroxy Phenylacetic Acid Pharmacophore Or Bioisostere
- Discovery And Structure-Activity Relationship Studies Of N-Substituted Indole Derivatives As Novel Mcl-1 Inhibitors
- Discovery Of 2-Indole-Acylsulfonamide Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods
- Discovery Of A Potent Inhibitor Of Melk That Inhibits Expression Of The Anti-Apoptotic Protein Mcl-1 And Tnbc Cell Growth
- Discovery Of Mcl-1 Inhibitors Based On A Thiazolidine-2, 4-Dione Scaffold
- Discovery Of Mcl-1 Inhibitors From Integrated High Throughput And Virtual Screening
- Discovery Of Mcl-1-Specific Inhibitor Azd5991 And Preclinical Activity In Multiple Myeloma And Acute Myeloid Leukemia
- Discovery Of Novel Biaryl Sulfonamide Based Mcl-1 Inhibitors
- Discovery Of Novel Small Molecule Inhibitors Of The Antiapoptotic Protein Mcl-1 Through High-Throughput Screening Approach
- Discovery Of Orally Bioavailable Novel Mcl-1 Inhibitors That Exhibit Selective Anti-Proliferative Activity In Mcl-1 Sensitive Cancer Cell Lines
- Discovery Of Potent 2-Indole-Acylsulfonamide Mcl-1 Inhibitors Using Structure Guided Fragment-Based Methods
- Discovery Of Potent And Selective Mcl-1 Inhibitors Using Fragment-Based Methods And Structure-Based Design.
- Discovery Of Potent Mcl-1/Bcl-Xl Dual Inhibitors By Using A Hybridization Strategy Based On Structural Analysis Of Target Proteins
- Discovery Of Potent Myeloid Cell Leukemia 1 (Mcl-1) Inhibitors Using Fragment-Based Methods And Structure-Based Design
- Discovery Of Potent Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors That Demonstrate In Vivo Activity In Mouse Xenograft Models Of Human Cancer
- Discovery Of Selective Mcl-1 Inhibitors Via Structure-Based Design And Structure-Activity Relationship Analysis
- Discovery Of Tricyclic Indoles That Potently Inhibit Mcl-1 Using Fragment-Based Methods And Structure-Based Design
- Discovery Of ฮ-Carboline Copper (Ii) Complexes As Mcl-1 Inhibitor And In Vitro And In Vivo Activity In Cancer Models
- Disruption Of Mcl-1ยท Bim Complex In Granzyme B-Mediated Mitochondrial Apoptosis
- Distinct Roles For Extracellular-Signal-Regulated Protein Kinase (Erk) Mitogen-Activated Protein Kinases And Phosphatidylinositol 3-Kinase In The Regulation Of Mcl-1 โฆ
- Distribution Of Bim Determines Mcl-1 Dependence Or Co-Dependence On Bcl-Xl/Bcl-2 In Multiple Myeloma
- Distribution Of Bim Determines Mcl-1 Dependence Or Codependence With Bcl-Xl/Bcl-2 In Mcl-1โExpressing Myeloma Cells
- Divaricoside Exerts Antitumor Effects, In Part, By Modulating Mcl-1 In Human Oral Squamous Cell Carcinoma Cells
- Dna Damage Response And Mcl-1 Destruction Initiate Apoptosis In Adenovirus-Infected Cells
- Dna Damaging Agent-Induced Apoptosis Is Controled By Mcl-1 Phosphorylation And Degradation Mediated By The Noxa/Mcl-1/Cdk2 Complex
- Dna Damaging Agent-Induced Apoptosis Is Regulated By Mcl-1 Phosphorylation And Degradation Mediated By The Noxa/Mcl-1/Cdk2 Complex
- Does N-Terminal Processing Of Mcl-1 Occur At Mitochondrial Outer Membrane Or Matrix?
- Downregulation Of Bcl-X L And Mcl-1 Is Sufficient To Induce Cell Death In Mesothelioma Cells Highly Refractory To Conventional Chemotherapy
- Down-Regulation Of C-Flip, Xiap And Mcl-1 Protein As Well As Depletion Of Reduced Glutathione Contribute To The Apoptosis Induction Of Glycyrrhenitic Acid Derivatives In โฆ
- Downregulation Of Mcl-1 And Upregulation Of Puma Using Mtor Inhibitors Enhance Antitumor Efficacy Of Bh3 Mimetics In Triple-Negative Breast Cancer
- Downregulation Of Mcl-1 By Daunorubicin Pretreatment Reverses Resistance Of Breast Cancer Cells To Tnf-Related Apoptosis-Inducing Ligand
- Downregulation Of Mcl-1 By Diallyl Disulfide Induces G2/M Arrest In Human Leukemia K562 Cells And Its Mechanism
- Down-Regulation Of Mcl-1 By Inhibition Of The Pi3-K/Akt Pathway Is Required For Cell Shrinkage-Dependent Cell Death
- Down-Regulation Of Mcl-1 By Small Interfering Rna Sensitizes Resistant Melanoma Cells To Fas-Mediated Apoptosis
- Downregulation Of Mcl-1 Has Anti-Inflammatory Pro-Resolution Effects And Enhances Bacterial Clearance From The Lung
- Downregulation Of Mcl-1 Potentiates Hdaci-Mediated Apoptosis In Leukemic Cells
- Downregulation Of Mcl-1 Synergizes The Apoptotic Response To Combined Treatment With Cisplatin And A Novel Fiber Chimeric Oncolytic Adenovirus
- Downregulation Of Mcl-1 Through Gsk-3ฮ Activation Contributes To Arsenic Trioxide-Induced Apoptosis In Acute Myeloid Leukemia Cells
- Downregulation Of Mcl-1 Through Inhibition Of Translation Contributes To Benzyl Isothiocyanate-Induced Cell Cycle Arrest And Apoptosis In Human Leukemia Cells
- Down-Regulation Of Mcl-1 With Antisense Technology Alters The Effect Of Various Cytotoxic Agents Used In Treatment Of Squamous Cell Carcinoma Of The Head And Neck
- Downregulation Of Mirโ20Bโ5P Facilitates Mycobacterium Tuberculosis Survival In Raw 264.7 Macrophages Via Attenuating The Cell Apoptosis By Mclโ1 Upregulation
- Down-Regulation Of Mir-320 Associated With Cancer Progression And Cell Apoptosis Via Targeting Mcl-1 In Cervical Cancer
- Downregulation Of Mir-363 Increases Drug Resistance In Cisplatin-Treated Hepg2 By Dysregulating Mcl-1
- Downregulation Of The Antiapoptotic Mclโ1 Protein And Apoptosis In Maโ11 Breast Cancer Cells Induced By An AntiโEpidermal Growth Factor ReceptorโPseudomonas โฆ
- Drug Combinations Co-Targeting Myeloid Cell Leukemia-1 (Mcl-1) Protein Can Overcome Microenvironmentally-Induced Multi-Drug Tolerance In Non-Hodgkin โฆ
- Dual Inhibition Of Bcl-Xl And Mcl-1 Is Required To Induce Tumour Regression In Lung Squamous Cell Carcinomas Sensitive To Fgfr Inhibition
- Dual Inhibition Of Mcl-1 By The Combination Of Carfilzomib And Tg02 In Multiple Myeloma
- Dual Inhibitors Of The Pro-Survival Proteins Bcl-2 And Mcl-1 Derived From Natural Compound Meiogynin A
- Dual Modulation Of Mcl-1 And Mtor Determines The Response To Sunitinib
- Dual Targeting Of Noxa/Mcl-1 Synergistically Induces Cell Death In Mantle Cell Lymphoma (Mcl) Cells
- Dynamic Changes In Mcl-1 Expression Regulate Macrophage Viability Or Commitment To Apoptosis During Bacterial Clearance
- Dynamic Changes In Mcl-1 Expression Regulate Macrophage Viability Or Commitment To Apoptosis During Bacterial Clearance.
- Dynamic Regulation Of Long-Chain Fatty Acid Oxidation By A Noncanonical Interaction Between The Mcl-1 Bh3 Helix And Vlcad
- Dynein Light Chain 1 Induces Assembly Of Large Bim Complexes On Mitochondria That Stabilize Mcl-1 And Regulate Apoptosis
- E.; Thorne, Rick F.; Allen, John; Hersey, Peter; Zhang, Xu Dong.โUp-Regulation Of Mcl-1 Is Critical For Survival Of Human Melanoma Cells Upon Endoplasmic โฆ
- E3 Ligase Fbw7 Participates In Oxidative StressโInduced Myocardial Cell Injury Via Interacting With Mclโ1
- Early Downregulation Of Mcl-1 Regulates Apoptosis Triggered By Cardiac Glycoside Unbs1450
- Eat/Mcl-1 Expression In The Human Embryonal Carcinoma Cells Undergoing Differentiation Or Apoptosis
- Eat/Mclโ1, A Member Of The Bclโ2 Related Genes, Confers Resistance To Apoptosis Induced By CisโDiammine Dichloroplatinum (Ii) Via A P53โIndependent Pathway
- Ectopic Overexpression Of Laptm5 Results In Lysosomal Targeting And Induces Mcl-1 Down-Regulation, Bak Activation, And Mitochondria-Dependent Apoptosis โฆ
- Effect Of (-)-Gossypol (At-101) On Transcriptional Regulation Of Noxa And Puma And On Mcl-1-Mediated Cancer Cell Resistance To Apoptosis
- Effect Of Acquired Resistance To Lapatinib In Her2-Positive Breast Cancer Cells On The Bcl-2 Family Members Mcl-1 And Bax.
- Effect Of Antisense Oligodeoxynucleotide Targeting Mcl-1 On Proliferation And Apoptosis Of Hepatocarcinoma Cells [J]
- Effect Of Arsenic Trioxide On Apoptosis In Lymphoblastoid Raji Cell Line With Relation To Expression Of Mcl-1 Gene
- Effect Of Curcumin On Apoptosis And Expression Of Apoptosis Regulating Proteins Mcl-1, Bax, Bak In Primary Acute Myeloid Leukemic Cells
- Effect Of Mcl-1 Antisense Oligonucleotide On Hela Cell Biology And Sensitivity Of Chemotherapy
- Effect Of Mir-29B On The Proliferation And Apoptosis Of Pulmonary Artery Smooth Muscle Cells By Targeting Mcl-1 And Ccnd2
- Effect Of Mir-363 On The Proliferation, Invasion And Apoptosis Of Laryngeal Cancer By Targeting Mcl-1
- Effect Of Vascular Endothelial Growth Factor On Apoptosis And Expression Of Bcl-2 And Mcl-1 In Acute Leukemia Cells
- Effective Caspase Inhibition Blocks Neutrophil Apoptosis And Reveals Mcl-1 As Both A Regulator And A Target Of Neutrophil Caspase Activation
- Effectiveness Of Small Interfering Rna (Sirna) Against The Mcl-1 Gene In A Canine Mammary Gland Tumor Cell Line
- Effects Of Casticin On Apoptosis And Expression Of Mcl-1 Protein In Ovarian Cancer Coc1 Cells [J]
- Effects Of Natural Products On Mcl-1 Expression And Function
- Effects Of Overexpressed Mcl-1 In Apoptosis Induced By The Er Stress Inducers Of Gastric Adenocarcinoma Cells [J]
- Effects Of The Mcl-1/Bcl-2 Inhibitor Gx015-070 (Obatoclaxยฎ) On Growth And Viability Of Canine And Human Neoplastic Mast Cells
- Efficacy Of Hcc Treatment With Proteasome Inhibitor Bortezomib Is Increased By Oncolytic Virotherapy Mediated Downregulation Of Mcl-1 And Bip
- Efficiently Kills Imatinib-Resistant Chronic Eosinophilic Leukemia Cells Harboring Gatekeeper Mutant T674I Fip1L1-Pdgfrฮฑ: Roles Of Mcl-1 And ฮ-Catenin
- Egf-Mediated Induction Of Mcl-1 At The Switch To Lactation Is Essential For Alveolar Cell Survival
- Egfr Mutations And Akt Phosphorylation Are Markers For Sensitivity To Combined Mcl-1 And Bcl-2/Xl Inhibition In Non-Small Cell Lung Cancer
- Egfr Regulates Mcl-1 Dependence In Chemoresistant And Acquired Abt-737-Resistant High-Risk Neuroblastoma (Hr Nb).
- Egfr Signaling Defines Mcl-1 Survival Dependency In Neuroblastoma
- Elevated Expression Of Mcl-1 Inhibits Apoptosis And Predicts Poor Prognosis In Patients With Surgically Resected Non-Small Cell Lung Cancer
- Elevated Expression Of The Apoptotic Regulator Mcl-1 At The Time Of Leukemic Relapse
- Elevated Mcl-1 Inhibits Thymocyte Apoptosis And Alters Thymic Selection
- Elevated Mcl-1 Perturbs Lymphopoiesis, Promotes Transformation Of Hematopoietic Stem/Progenitor Cells, And Enhances Drug Resistance
- Elimination Of Mcl-1 Is Required For The Initiation Of Apoptosis Following Ultraviolet Irradiation
- Elk4 Neutralization Sensitizes Glioblastoma To Apoptosis Through Downregulation Of The Anti-Apoptotic Protein Mcl-1
- Emerging Role Of Mcl-1 In Actively Counteracting Bh3-Only Proteins In Apoptosis
- Endiandric Acid Analogues From Beilschmiedia Ferruginea As Dual Inhibitors Of Bcl-Xl/Bak And Mcl-1/Bid Interactions
- Endogenous Association Of Bim Bh3โOnly Protein With Mclโ1, BclโXl And Bclโ2 On Mitochondria In Human B Cells
- Endogenous Bak Inhibitors Mcl-1 And Bcl-Xl: Differential Impact On Trail Resistance In Bax-Deficient Carcinoma
- Enhanced Apoptotic Effects By Downregulating Mcl-1: Evidence For The Improvement Of Photodynamic Therapy With Celecoxib
- Enhanced Apoptotic Effects By The Combination Of Curcumin And Methylseleninic Acid: Potential Role Of Mclโ1 And Fak
- Enhanced Killing Of Melanoma Cells By Simultaneously Targeting Mcl-1 And Noxa
- Enhanced Production Of Anti-Pd1 Antibody In Cho Cells Through Transient Co-Transfection With Anti-Apoptotic Genes Bcl-Xl And Mcl-1
- Enhancement Of Cell Survival By Stromal Cell-Derived Factor-1/Cxcl12 Involves Activation Of Creb And Induction Of Mcl-1 And C-Fos In Factor-Dependent Human Cell โฆ
- Enhancement Of Chemosensitivity By Simultaneously Silencing Of Mcl-1 And Survivin Genes Using Small Interfering Rna In Human Myelomonocytic Leukaemia
- Ephrina1 Induces Microrna-302B Expression In Malignant Mesothelioma Cells And Suppresses Tumor Growth Via Repression Of Mcl-1 Gene
- Epidermal Growth Factor (Egf) Suppresses Staurosporine-Induced Apoptosis By Inducing Mcl-1 Via The Mitogen-Activated Protein Kinase Pathway
- Epidermal Growth Factor Regulates Mcl-1 Expression Through The Mapk-Elk-1 Signalling Pathway Contributing To Cell Survival In Breast Cancer
- Epox Inhibits Angiogenesis By Degradation Of Mcl-1 Through Erk Inactivation
- Er Stress Sensitizes Cells To Trail Through Down-Regulation Of Flip And Mcl-1 And Perk-Dependent Up-Regulation Of Trail-R2
- Eradication Of Acute Myeloid Leukemia Is Enhanced By Combined Bcl-2 And Mcl-1 Targeting
- Erk Signaling Induces Apoptosis Of Acute Myelogenous Leukemia Cells Via Inhibition Of Eukaryotic Initiation Factor 4E-Binding Protein 1 And Down-Regulation Of Mcl-1
- Erk1/2 And The Bcl-2 Family Proteins Mcl-1, Tbid, And Bim Are Involved In Inhibition Of Apoptosis During Persistent Chlamydia Psittaci Infection
- Erk1/2โDependent Phosphorylation Of Bimel Promotes Its Rapid Dissociation From Mclโ1 And BclโXl
- Erratum: Antigen-Affinity Controls Pre-Germinal Center B Cell Selection By Promoting Mcl-1 Induction Through Baff Receptor Signaling
- Erratum: The Ratio Of Mcl-1 And Noxa Determines Abt737 Resistance In Squamous Cell Carcinoma Of The Skin
- Establishing Drug Discovery And Identification Of Hit Series For The Anti-Apoptotic Proteins, Bcl-2 And Mcl-1
- Estrogen Regulation Of Anti-Apoptotic Bcl-2 Family Member Mcl-1 Expression In Breast Cancer Cells
- Ethacrynic Acid Oxadiazole Analogs Induce Apoptosis In Malignant Hematologic Cells Through Downregulation Of Mcl-1 And C-Flip, Which Was Attenuated By Gstp1-1
- Ets-1 Mediates Upregulation Of Mcl-1 Downstream Of Xbp-1 In Human Melanoma Cells Upon Er Stress
- Eupafolin Enhances Trail-Mediated Apoptosis Through Cathepsin S-Induced Down-Regulation Of Mcl-1 Expression And Ampk-Mediated Bim Up-Regulation In โฆ
- Evaluating The Role Of Mcl-1 And Its Interacting Partners In Radioresistance Of Oral Cancer Cells
- Evaluation And Critical Assessment Of Putative Mcl-1 Inhibitors
- Evaluation Of Mcl-1 Inhibitors In Preclinical Models Of Multiple Myeloma
- Evaluation Of Pten And Mcl-1 Expressions In Nsclc Expressing Wild-Type Or Mutated Egfr
- Evidence For A Protective Role Of Mcl-1 In Proteasome Inhibitor-Induced Apoptosis
- Evodiamine Induces Apoptosis And Enhances Apoptotic Effects Of Erlotinib In Wild-Type Egfr Nsclc Cells Via S6K1-Mediated Mcl-1 Inhibition
- Evodiamine Induces Apoptosis And Enhances Trail-Induced Apoptosis In Human Bladder Cancer Cells Through Mtor/S6K1-Mediated Downregulation Of Mcl-1
- Exon Skipping In Mcl-1 Results In A Bcl-2 Homology Domain 3 Only Gene Product That Promotes Cell Death
- Exposure To The Viral By-Product Dsrna Or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis Via A Bim/Mcl-1 Imbalance
- Expression And Clinical Significance Of Mcl-1 In B Cell Non-Hodgkin’S Lymphoma
- Expression And Clinical Significance Of Mcl-1 In T-Cell Non-Hodgkin’S Lymphoma
- Expression And Prognostic Relevance Of Mcl-1 In Breast Cancer
- Expression And Regulation Of The Anti-Apoptotic Mcl-1 Protein In Human B-Cell Lymphoma.
- Expression And Significance Of Mir-125A And Mcl-1 In Intestinal Tissue After Massive Small Bowel Resection In Rat
- Expression And Significance Of Mrna And Protein Of Eif4E, P-Eif4E And Mcl-1 In Pathological Scar
- Expression Levels Of P18Ink4C Modify The Cellular Efficacy Of Cyclin-Dependent Kinase Inhibitors Via Regulation Of Mcl-1 Expression In Tumor Cell Lines
- Expression Of Bcl-2, Bcl-X, Mcl-1, Bax And Bak In Human Uterine Leiomyomas And Myometrium During The Menstrual Cycle And After Menopause
- Expression Of Bcl-Xl And Mcl-1 In The Nonmelanoma Skin Cancers Of Renal Transplant Recipients
- Expression Of Mcl-1 And Bak Proteins In Nutritional Anemia And Its Clinical Significance
- Expression Of Mcl-1 And Bcl-2 Oncoproteins In Reactive And Neoplastic Lymphoid Tissues
- Expression Of Mcl-1 And Ki-67 In Papillary Thyroid Carcinomas
- Expression Of Mcl-1 And Microrna-29A In Extranodal Nk/T-Cell Lymphoma Tissue
- Expression Of Mcl-1 And P53 Proteins Predicts The Survival Of Patients With T3 Gastric Carcinoma
- Expression Of Mcl-1 In Cerebellar Granule Neurons Is Regulated By Igf-I In A Developmentally Specific Fashion
- Expression Of Mclโ1 In Mantle Cell Lymphoma Is Associated With HighโGrade Morphology, A High Proliferative State, And P53 Overexpression
- Expression Of Mcl-1 In Primary Acute Myeloid Leukemia Cells And Its Clinical Significance
- Expression Of Mcl-1 Protein In Human Cervical Lesions And Its Significance [J]
- Expression Of Mcl-1 Splicing Variants In Clear-Cell Renal Cancer And Their Correlation With Histopathological Parameters And Prognosis
- Expression Of The Bcl-2 Homologue Mcl-1 Correlates With Survival Of Peripheral Blood B Lymphocytes
- Expression Of The Epstein Barr Virus Transforming Protein Lmp1 Causes A Rapid And Transient Stimulation Of The Bcl-2 Homologue Mcl-1 Levels In B-Cell Lines
- Expression Of Vegf-A/C, Vegf-R2, Pdgf-ฮ/ฮ, C-Kit, Egfr, Her-2/Neu, Mcl-1 And Bmi-1 In Merkel Cell Carcinoma
- Expression Pattern And Biologic Relevance Of Bcl-2 And Mcl-1 In Pulmonary Neuroendocrine Tumors.
- Expression Profile Of Bcl-2, Bcl-Xl, And Mcl-1 Predicts Pharmacological Response To The Bcl-2 Selective Antagonist Venetoclax In Multiple Myeloma Models
- Exth-55. Concomitant Inhibition Of Rac1 And Bcl-2/Bcl-Xl Interferes With The Mcl-1/Usp9X Axis And Yields Synergistic Anti-Glioma Activity
- Farnesyltransferase Inhibitor Bms-214662 Induces Apoptosis In Myeloma Cells Through Puma Up-Regulation, Bax And Bak Activation, And Mcl-1 Elimination
- Fas-Mediated Neutrophil Apoptosis Is Accelerated By Bid, Bak, And Bax And Inhibited By Bcl-2 And Mcl-1
- Fbw7 Mutations Mediate Resistance Of Colorectal Cancer To Targeted Therapies By Blocking Mcl-1 Degradation
- Fbw7-Dependent Mcl-1 Degradation Mediates The Anticancer Effect Of Hsp90 Inhibitors
- Fbxo4 Inhibits Lung Cancer Cell Survival By Targeting Mcl-1 For Degradation
- Fbxw 7 Modulates Malignant Potential And CisplatinโInduced Apoptosis In Cholangiocarcinoma Through Notch 1 And Mcl 1
- Fenretinide Inactivation Of Mcl-1 Enhanced Activity Of The Bcl-2 Family Inhibitor Abt-737 In Acute Lymphoblastic Leukemia Cell Lines
- First Evidence That Oligopyridines, ฮ-Helix Foldamers, Inhibit Mcl-1 And Sensitize Ovarian Carcinoma Cells To Bcl-Xl-Targeting Strategies
- First Mcl-1-Selective Bh3 Mimetics As Potential Therapeutics For Targeted Treatment Of Cancer
- First-In-Class Cell-Penetrating Proteins Targeting Mcl-1 Induce Tumor Cell Apoptosis And Inhibition Of Tumor Growth In Vivo
- Five-Co-Ordinate Cobalt (Ii) And Nickel (Ii) Complexes Of 1, 4, 8, 11-Tetrakis (Diphenylphosphinomethyl)-1, 4, 8, 11-Tetraazacyclotetradecane (Tpta),[Mcl (Tpta)] X [X= Clo4 โฆ
- Fl118, A Survivin/Mcl-1/Xiap/Ciap2-Selective Inhibitor, Effectively Inhibits Human Mesothelioma Xenograft Growth In Animal Models.
- Flash Knockdown Sensitizes Cells To Fas-Mediated Apoptosis Via Down-Regulation Of The Anti-Apoptotic Proteins, Mcl-1 And Cflip Short
- Flavones Induce Neutrophil Apoptosis By Down-Regulation Of Mcl-1 Via A Proteasomal-Dependent Pathway
- Flavonoid Morin Inhibits Proliferation And Induces Apoptosis Of Melanoma Cells By Regulating Reactive Oxygen Species, Sp1 And Mcl-1
- Flavopiridol Decreases Mcl-1 And Initiates Early Mitochondrial Damage In Chronic Lymphocytic Leukemia (Cll) Cells.
- Flavopiridol Decreases Mcl-1 And Xiap In Acute Myeloid Leukemia Cell Resulting In Augmentation Of Sorafenib-Induced Apoptosis
- Flexibility And Specificity Of The Interaction Of Mcl-1 With Bim Bh3
- Flexibility Enables To Discriminate Between Ligands: Lessons From Structural Ensembles Of Bcl-Xl And Mcl-1
- Flt3 Inhibitor Fi-700 Neutralizes Mcl-1 And Enhances P53-Mediated Apoptosis In Acute Myeloid Leukemia (Aml) Cells With Activating Mutations Of Flt3 Via Mcl-1 โฆ
- Flt3 Kinases In Flt3-Itd Acute Myeloid Leukemia Post-Translationally Downregulates The Anti-Apoptotic Protein Mcl-1 Through Downregulation Of The Mcl-1 โฆ
- Flt3-Itd Confers Resistance To The Pi3K/Akt Pathway Inhibitors By Protecting The Mtor/4Ebp1/Mcl-1 Pathway Through Stat5 Activation In Acute Myeloid โฆ
- Flt3-Itd Up-Regulates Mcl-1 To Promote Survival Of Stem Cells In Acute Myeloid Leukemia Via Flt3-ItdโSpecific Stat5 Activation
- Fludarabine Induces Apoptosis In Chronic Lymphocytic Leukemia-The Role Of P53, Bcl-2, Bax, Mcl-1, And Bag-1 Proteins
- Fluorouracil-Induced Death Of Jurkat T-CellsโA Role For Caspases And Mcl-1
- Foam Cell Formation And Atherosclerotic Plaque Apoptosis And Markedly Decreased Neutrophil Recruitment In Ldlr-/-Mice Lacking Macrophage Mcl-1
- Forodesine Induces P53-Independent Apoptosis In Chronic Lymphocytic Leukemia Through Caspase-8 Activation, Mcl-1 Downregulation, Conformational Changes Of Bax โฆ
- FragmentโBased Design, Synthesis, And Biological Evaluation Of 1โSubstitutedโIndoleโ2โCarboxylic Acids As Selective Mclโ1 Inhibitors
- Fragment-Based Design, Synthesis, And Biological Evaluation Of N-Substituted-5-(4-Isopropylthiophenol)-2-Hydroxynicotinamide Derivatives As Novel Mcl-1 Inhibitors
- Fragment-Based Discovery Of Potent Inhibitors Of The Anti-Apoptotic Mcl-1 Protein
- Free Ligand 1D Nmr Conformational Signatures To Enhance Structure Based Drug Design Of A Mcl-1 Inhibitor (Azd5991) And Other Synthetic Macrocycles
- Frequent Stat3 Activation Is Associated With Mclโ1 Expression In Nasal NkโCell Lymphoma
- From Meiogynin A To The Synthesis Of Dual Inhibitors Of Bcl-Xl And Mcl-1 Anti-Apoptotic Proteins
- Fty720 Enhances Trail-Mediated Apoptosis By Up-Regulating Dr5 And Down-Regulating Mcl-1 In Cancer Cells
- Fty720 Induces Autophagy-Associated Apoptosis In Human Oral Squamous Carcinoma Cells, In Part, Through A Reactive Oxygen Species/Mcl-1-Dependent โฆ
- Functional Analysis Of The Human Mcl-1 Gene
- Functional Capacity Of Mcl-1-Specific Cytotoxic T-Cells
- Furowanin A-Induced Autophagy Alleviates Apoptosis And Promotes Cell Cycle Arrest Via Inactivation Stat3/Mcl-1 Axis In Colorectal Cancer
- Galectin 3 Protein Network Analysis By Reverse Protein Arrays Demonstrates Regulation Of Mcl-1, Pkc Delta And Cd74 Associated With Poor Survival In Patients โฆ
- Gamma Irradiation Of Human Leukaemic Cells Hl-60 And Molt-4 Induces Decrease In Mcl-1 And Bid, Release Of Cytochrome C, And Activation Of Caspase-8 And โฆ
- Gamma-Secretase Inhibition Attenuates Oxaliplatin-Induced Apoptosis Through Increased Mcl-1 And/Or Bcl-Xl In Human Colon Cancer Cells
- Gastrin Increases Mcl-1 Expression In Type I Gastric Carcinoid Tumors And A Gastric Epithelial Cell Line That Expresses The Cck-2 Receptor
- Gcs-100, A Novel Galectin-3 Antagonist, Modulates Mcl-1, Noxa, And Cell Cycle To Induce Myeloma Cell Death
- Gdc-0941 Sensitizes Breast Cancer To Abt-737 In Vitro And In Vivo Through Promoting The Degradation Of Mcl-1
- Genetic Biomarkers Predict Response To Dual Bcl-2 And Mcl-1 Targeting In Acute Myeloid Leukaemia Cells
- Genipin Induces Mitochondrial Dysfunction And Apoptosis Via Downregulation Of Stat3/Mcl-1 Pathway In Gastric Cancer
- Geraniin Suppresses Ovarian Cancer Growth Through Inhibition Of Nfโฮb Activation And Downregulation Of Mclโ1 Expression
- Gfi-1 Inhibits Proliferation And Colony Formation Of P210Bcr/Abl-Expressing Cells Via Transcriptional Repression Of Stat 5 And Mcl-1
- Glucocorticoid-Induced Leucine Zipper Is Expressed In Human Neutrophils And Promotes Apoptosis Through Mcl-1 Down-Regulation
- Glutamine Catabolism Maintains Mcl-1 Expression In Glucose-Deprived Multiple Myeloma
- Glutathione And Bcl-2 Targeting Facilitates Elimination By Chemoradiotherapy Of Human A375 Melanoma Xenografts Overexpressing Bcl-Xl, Bcl-2, And Mcl-1
- Glycogen Synthase Kinase 3ฮ And 3ฮ Mediate A Glucose-Sensitive Antiapoptotic Signaling Pathway To Stabilize Mcl-1
- Glycogen Synthase Kinase-3 Regulates Mitochondrial Outer Membrane Permeabilization And Apoptosis By Destabilization Of Mcl-1
- Glycolysis Inhibition Sensitizes Tumor Cells To Death Receptors-Induced Apoptosis By Amp Kinase Activation Leading To Mcl-1 Block In Translation
- Glycolysis Inhibition Targets Mcl-1 To Restore Sensitivity Of Lymphoma Cells To Abt-737-Induced Apoptosis
- Gm-Csf Rescues Tf-1 Cells From Growth Factor Withdrawal-Induced, But Not Differentiation-Induced Apoptosis: The Role Of Bcl-2 And Mcl-1
- Gรถ6976, A Flt3 Kinase Inhibitor, Exerts Potent Cytotoxic Activity Against Acute Leukemia Via Inhibition Of Survivin And Mcl-1
- Go6976, A Potent Flt3 Kinase Inhibitor, Exerts Antiproliferative Activity Against Acute Myeloid Leukemia Via Inhibition Of Survivin And Mcl-1 In The Presence Of โฆ
- Gossypol Induces Apoptosis In Multiple Myeloma Cells By Inhibition Of Interleukin-6 Signaling And Bcl-2/Mcl-1 Pathway
- Granulocyte Macrophage Colony-Stimulating Factor Signaling And Proteasome Inhibition Delay Neutrophil Apoptosis By Increasing The Stability Of Mcl-1
- Gsk3ฮ And Mcl-1 Mediate Cardiomyocyte Apoptosis In Response To High Glucose
- Guarding Effector T-Cell Survival: All For One, Mcl-1 For All?
- H1, A Derivative Of Tetrandrine, Enhances The Efficacy Of 5-Fu In Bel7402/5-Fu Cells Via Suppressing Stat3/Mcl-1 And Inducing Puma
- Harringtonine Induces Apoptosis In Nb4 Cells Through Down-Regulation Of Mcl-1
- Hb-Egf Is Associated With Dna Damage And Mcl-1 Turnover In Human Glioma Cell Lines Treated By Temozolomide
- Hbx Sensitizes Cells To Oxidative Stress-Induced Apoptosis By Accelerating The Loss Of Mcl-1 Protein Via Caspase-3 Cascade
- Hepatitis B Virus X Protein Enhances Cisplatin-Induced Hepatotoxicity Via A Mechanism Involving Degradation Of Mcl-1
- Hepatocyte Growth Factor Induces Mclโ1 In Primary Human Hepatocytes And Inhibits Cd95โMediated Apoptosis Via Akt
- Herceptin Sensitizes Erbb2 (Her2/Neu) Over Expressing Cells To Apoptosis By Reducing Anti-Apoptotic Mcl-1 Expression
- Herceptin Sensitizes Erbb2โOverexpressing Cells To Apoptosis By Reducing Antiapoptotic Mcl-1 Expression
- Heterodimerization Of Bak And Mcl-1 Activated By Detergent Micelles
- Hifโ1ฮ Has An AntiโApoptotic Effect In Human Airway Epithelium That Is Mediated Via Mclโ1 Gene Expression
- High Bcl-2/Mcl-1 Gene Expression Ratio Identifies Molecular Sub-Groups Of Multiple Myeloma Patients Extremely Sensitive To Abt-737
- High Expression Of Mcl-1 In Alk Positive And Negative Anaplastic Large Cell Lymphoma
- High-Grade Malignant Non-Hodgkin’S Lymphomas Differ From Low-Grade Lymphomasin The Extent Of Apoptosis Andtheir Expression Of Bcl-2, Mcl-1, Bax And P53
- High-Quality Nmr Structure Of Human Anti-Apoptotic Protein Domain Mcl-1 (171-327) For Cancer Drug Design
- Hispidulin Sensitizes Human Ovarian Cancer Cells To Trail-Induced Apoptosis By Ampk Activation Leading To Mcl-1 Block In Translation
- Homoharringtonine Interacts Synergistically With Bortezomib In Nhl Cells Through Mcl-1 And Noxa-Dependent Mechanisms
- Homoharringtonine Reduced Mcl-1 Expression And Induced Apoptosis In Chronic Lymphocytic Leukemia
- Hot-Spots Of Mcl-1 Protein.
- Hot-Spots Of Mcl-1 Protein: Miniperspective
- Hsp90 Inhibitor 17-Aag Sensitizes Bcl-2 Inhibitor (-)-Gossypol By Suppressing Erk-Mediated Protective Autophagy And Mcl-1 Accumulation In Hepatocellular โฆ
- Hsp90 Inhibitor Nvp-Auy922 Enhances Trail-Induced Apoptosis By Suppressing The Jak2-Stat3-Mcl-1 Signal Transduction Pathway In Colorectal Cancer Cells
- Htlv-1 Tax Stabilizes Mcl-1 Via Traf6-Dependent K63-Linked Polyubiquitination To Promote Cell Survival And Transformation
- Hu J, Dang N, Menu E, Et Al. Activation Of Atf4 Mediates Unwanted Mcl-1 Accumulation By Proteasome Inhibition. Blood. 2012; 119 (3): 826-837.
- Human Chronic Leukemic Cells By Abnobaviscumยฎ Flaxini, Mistletoe Extracts From Ash Tree: Involvement Of Activation Of Caspases, Mcl-1 Down-Regulation, And โฆ
- Human Eosinophils Express Bcl-2 Family Proteins: Modulation Of Mcl-1 Expression By Ifn-ฮ
- Human Glioma Cells To Histone Deacetylase Inhibitors Depends On Reactive Oxygen Species Production, Mitochondrial Dysfunction, Noxa Upregulation And Mcl-1 โฆ
- Human Oral Cancers Have Altered Expression Of Bclโ2 Family Members And Increased Expression Of The AntiโApoptotic Splice Variant Of Mclโ1
- Human Papillomavirus Type 16/18 Up-Regulates The Expression Of Interleukin-6 And Antiapoptotic Mcl-1 In NonโSmall Cell Lung Cancer
- Humanized Mcl-1 Mice Enable Accurate Preclinical Evaluation Of Mcl-1 Inhibitors Destined For Clinical Use
- Hydroxyquinoline-Derived Compounds And Analoguing Of Selective Mcl-1 Inhibitors Using A Functional Biomarker
- Hyperactive Ptpn11 Mutations Alters Leukemic Stem Cell Frequency Through Mcl-1 Overexpression
- Hypoxia Selects For High-Metastatic Lewis Lung Carcinoma Cells Overexpressing Mcl-1 And Exhibiting Reduced Apoptotic Potential In Solid Tumors
- Hypoxia-Induced P38 Mapk Activation Reduces Mcl-1 Expression And Facilitates Sensitivity Towards Bh3 Mimetics In Chronic Lymphocytic Leukemia
- Hypoxic Human Cancer Cells Are Sensitized To Bh-3 MimeticโInduced Apoptosis Via Downregulation Of The Bcl-2 Protein Mcl-1
- Identification Of A Non-Canonical Bh3 Peptide That Binds The Bh3 Pocket Of Mcl-1
- Identification Of A Novel Mcl-1 Protein Binding Motif
- Identification Of An Hla-A1 Restricted Ctl Epitope From Mcl-1
- Identification Of Mcl-1 As A Bcr/Abl-Dependent Target In Chronic Myeloid Leukemia (Cml): Evidence For Cooperative Antileukemic Effects Of Imatinib And Mcl-1 โฆ
- Identification Of Novel Mcl-1 Inhibitors Using Integrated Screening Approach: Combining High Throughput And Virtual Screening.
- Identification Of SmallโMolecule Inhibitors Of The Antiapoptotic Protein Myeloid Cell Leukaemiaโ1 (Mclโ1)
- Identifying Mcl-1 Protein Dependencies Using Dimerization-Specific Antibody Biomarker For Predicting Response To Targeted Apoptosis Inducing Therapies.
- Identifying The Druggable Interactome Of Ews-Fli1 Reveals Mcl-1 Dependent Differential Sensitivities Of Ewing Sarcoma Cells To Apoptosis Inducers
- Iex-1-Induced Cell Death Requires Bim And Is Modulated By Mcl-1
- Ifn-ฮ And Bortezomib Overcome Bcl-2 And Mcl-1 Overexpression In Melanoma Cells By Stimulating The Extrinsic Pathway Of Apoptosis
- Ige-Dependent Activation Of Human Mast Cells Up-Regulates Flip And Mcl-1 Anti-Apoptotic Proteins
- Ilโ15 Regulates Bclโ2 Family Members Bim And Mclโ1 Through Jak/Stat And Pi3K/Akt Pathways In T Cells
- Il-22 Accelerates Thymus Regeneration Via Stat3/Mcl-1 And Decreases Chronic Graft-Versus-Host Disease In Mice After Allotransplants
- Il-27 Inhibits Ifn-ฮ Induced Autophagy By Concomitant Induction Of Jak/Pi3 K/Akt/Mtor Cascade And Up-Regulation Of Mcl-1 In Mycobacterium Tuberculosis H37Rv โฆ
- Il-32ฮ Delays Spontaneous Apoptosis Of Human Neutrophils Through Mcl-1, Regulated Primarily By The P38 Mapk Pathway
- Il-6 Inhibits Apoptosis And Retains Oxidative Dna Lesions In Human Gastric Cancer Ags Cells Through Up-Regulation Of Anti-Apoptotic Gene Mcl-1
- Il-6 Inhibits Apoptosis Of Human Myeloma Cell Line Xg-7 Through Activation Of Jak/Stat Pathway And Up-Regulation Of Mcl-1.
- Il-6 Rescues The Hyporesponsiveness Of C-Rel Deficient B Cells Independent Of Bcl-Xl, Mcl-1, And Bcl-2
- Ilโ6 UpโRegulates Mclโ1 In Human Myeloma Cells Through Jak/Stat Rather Than Ras/Map Kinase Pathway
- Il-6-Independent Expression Of Mcl-1 In Human Multiple Myeloma
- Imbalance In Alternative Splicing Of Mcl-1 Inhibits Apoptosis In Diffuse Large B-Cell Lymphoma
- Immunoblot Analysis Of Cellular Expression Of Bcl-2 Family Proteins, Bcl-2, Bax, Bcl-X And Mcl-1, In Human Peripheral Blood And Lymphoid Tissues
- Immunoexpressions Of P21, Rb, Mcl-1 And Bad Gene Products In Normal, Hyperplastic And Carcinomatous Human Prostates
- Immunohistochemical Analysis Of Bcl-2, Bax, Bcl-X, And Mcl-1 Expression In Pancreatic Cancers
- Immunohistochemical Analysis Of Bcl-2, Bax, Bcl-X, And Mcl-1 Expression In Prostate Cancers.
- Immunohistochemical Analysis Of Bcl-2, Bax, Mcl-1, And Bcl-X Expression In Ovarian Surface Epithelial Tumors.
- Immunohistochemical Analysis Of Bcl-2, Bcl-X, Mcl-1, And Bax In Tumors Of Central And Peripheral Nervous System Origin.
- Immunohistochemical Analysis Of Mcl-1 And Bcl-2 Proteins In Normal And Neoplastic Lymph Nodes.
- Immunohistochemical Analysis Of Mcl-1 Protein In Human Tissues. Differential Regulation Of Mcl-1 And Bcl-2 Protein Production Suggests A Unique Role For Mcl-1 In โฆ
- Immunohistochemical Analysis Of The Antiapoptotic Mclโ1 And Bclโ2 Proteins In Follicular Lymphoma
- Immunohistochemical Localization Of Mclโ1 And Bclโ2 Proteins In Thymic Epithelial Tumours
- Immunohistochemical Measurement And Expression Of Mcl-1 In Infertile Testes
- Immunohistochemical Staining For Bcl-2 And Mcl-1 In Intrathyroidal Epithelial Thymoma (Itet)/Carcinoma Showing Thymus-Like Differentiation (Castle) And Cervical โฆ
- Impact Of Elevated Anti-Apoptotic Mcl-1 And Bcl-2 On The Development And Treatment Of Mll-Af9 Aml In Mice
- Imperatorin Acts As A Cisplatin Sensitizer Via Downregulating Mcl-1 Expression In Hcc Chemotherapy
- Imperatorin Induces Mcl-1 Degradation To Cooperatively Trigger Bax Translocation And Bak Activation To Suppress Drug-Resistant Human Hepatoma
- Imperatorin Targets Mcl-1 To Sensitize Cd133+ Lung Cancer Cells To ฮฮด-T Cell-Mediated Cytotoxicity
- Importance Of Mcl-1 For Alveolar Macrophage ApoptosisโAssociated Bacterial Killing
- Improved Binding Affinities Of Pyrrolidine Derivatives As Mcl-1 Inhibitors By Modifying Amino Acid Side Chains
- In B-Cells Isolated From Chronic Lymphocytic Leukemia Patients And Leukemia Cell Lines Is Overcome By The Pleiotropic Kinase Inhibitor Quercetin Through Mcl-1 Down โฆ
- In Human Multiple Myeloma Cells Promotes Myeloma Cell Growth And Survival In The Bone Marrow Microenvironment Via Upregulated Mcl-1 And Nfฮบb Signaling
- In Non-Transformed Cells Bak Activates Upon Loss Of Anti-Apoptotic Bcl-X L And Mcl-1 But In The Absence Of Active Bh3-Only Proteins
- In Silico Approaches To Identify Novel Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors For Treatment Of Cancer
- In Vitro Thymidine Kinase/Ganciclovir-Based Suicide Gene Therapy Using Replication Defective Herpes Simplex Virus-1 Against Leukemic B-Cell Malignancies (Mcl, Hcl โฆ
- In Vivo Localisation And Stability Of Human Mclโ1 Using Green Fluorescent Protein (Gfp) Fusion Proteins
- In Vivo Rna Silencing Ofthe Mcl-1 Gene Confers Increased Susceptibility Of Melanoma Cells To Apoptosis
- In Whole Blood: Involvement Of The Phosphoinositide 3-Kinase/Akt And Nf-ฮb Signaling Pathways, Leading To Increased Levels Of Mcl-1, A1, And Phosphorylated Bad
- Increased Expression Of Mcl-1 And Bcl-Xl And Decreased Expression Of Bcl-2 Associated With Melanoma Progression And Transcription Factors
- Increased Expression Of Mcl-1 Is Required For Protection Against Serum Starvation In Phosphatase And Tensin Homologue On Chromosome 10 Null Mouse Embryonic โฆ
- Increased Expression Of Mclโ1 Is Responsible For The Blockage Of TrailโInduced Apoptosis Mediated By Egf/Erbb1 Signaling Pathway
- Increased Foam Cell Formation And Atherosclerotic Plaque Apoptosis In Ldlrโ/โ Mice Lacking Macrophage Mcl-1
- Increased Leukocyte Survival And Accelerated Onset Of Lymphoma In The Absence Of Mcl-1 S159-Phosphorylation
- Increased Mclโ1 Expression Is Associated With Poor Prognosis In Ovarian Carcinomas
- Increased Mcl-1 Expression Predicts Poor Prognosis And Disease Recurrence In Acute Myeloid Leukemia
- Increased Synthesis Of Mcl-1 Protein Underlies Initial Survival Of Egfr-Mutant Lung Cancer To Egfr Inhibitors And Provides A Novel Drug Target
- Individualized Mitochondrial Functional Approach To Combination Of Bcl-2 And Mcl-1 Antagonism In Acute Myeloid Leukemia
- Indomethacin Causes Renal Epithelial Cell Injury Involving Mcl-1 Down-Regulation
- Induces Anti-Proliferative And Apoptotic Activities In Human Hormone-Refractory Prostate Cancer Through Histamine Receptor-Independent Mcl-1 Cleavage And Bak Up โฆ
- Induces Apoptosis In A Subset Of Cancer Cells (Lung Cancer, Colon Cancer And Mesothelioma) By Disrupting Bcl-Xl And Mcl-1 ProteinโProtein Interactions โฆ
- Induces Apoptosis Of Aml Blasts And Their Terminal Differentiation By Blocking Akt/Erk Survival Signals And Downregulating Bcl-2, Mcl-1 And Cyclin-D1 โฆ
- Induces Cell Death In Multiple Myeloma Cells By Inhibition Of Rna Polymerase IiโDependent Transcription And Down-Regulation Of Mcl-1
- Induces Expression Of Pim Kinases Through Stat5 To Confer Resistance To The Pi3K/Akt Pathway Inhibitors On Leukemic Cells By Enhancing The Mtorc1/Mcl-1 โฆ
- Inducing Apoptosis And Enhancing Chemosensitivity To Gemcitabine Via Rna Interference Targeting Mcl-1 Gene In Pancreatic Carcinoma Cell
- Induction By Clinically Active Flt3 Inhibitors In Flt3-Itd Acute Myeloid Leukemia Cells In Vitro And In Vivo Through Synergistic Downregulation Of Mcl-1 And Of Bcl โฆ
- Induction Of Apoptosis And Anti-Tumor Effects Of A Novel Pan Inhibitor Of Bcl-2 And Mcl-1 Apogossypolone (Apog2) In Multiple Myeloma Cells.
- Induction Of Apoptosis By Mcl-1 Inhibitors In Chronic Lymphocytic Leukemia Cells
- Induction Of Apoptosis In Large Granular Lymphocyte (Lgl) Leukemia By Jak Tyrosine Kinase Inhibitor Ag-490: Role Of Stat3-Regulated Mcl-1
- Induction Of Noxa Sensitizes Human Colorectal Cancer Cells Expressing Mcl-1 To The Small-Molecule Bcl-2/Bcl-Xl Inhibitor, Abt-737
- Infectious Pancreatic Necrosis Virus Induces Apoptosis Due To Down-Regulation Of Survival Factor Mcl-1 Protein Expression In A Fish Cell Line
- Inhibiting Mcl-1 With An Antisense Oligonucleotide Induces Cell Death In Acute Myeloid Leukemia Cells
- Inhibiting Mitochondrial-Dependent Proteolysis Of Mcl-1 Promotes Resistance To Dna Damage
- Inhibition Delays Neutrophil Apoptosis Via Cyclic Amp-Independent Activation Of Protein Kinase A And Protein Kinase A-Mediated Stabilization Of Mcl-1 And X-Linked โฆ
- Inhibition Of Antiapoptotic Bcl-Xl, Bcl-2, And Mcl-1 Proteins By Small Molecule Mimetics
- Inhibition Of Anti-Apoptotic Mcl-1 Exerts Anti-Leukemia Activity Through Modulation Of Leukemia-Stromal Interactions And Metabolic Functions In Aml
- Inhibition Of Anti-Apoptotic Protein Mcl-1 And Epigenetic Reader Brd4 With Small Molecule Inhibitors: Structure-Based Drug Design And Polypharmacology
- Inhibition Of Constitutive And Bcr-Induced Syk Activation Downregulates Mcl-1 And Induces Apoptosis In Chronic Lymphocytic Leukemia B Cells
- Inhibition Of Cyclin E1 Overcomes Temozolomide Resistance In Glioblastoma By Mclโ1 Degradation
- Inhibition Of Cyclin E1 Sensitizes Hepatocellular Carcinoma Cells To Regorafenib By Mcl-1 Suppression
- Inhibition Of Mcl-1 Blocks The Development Of Kras-Driven Adenocarcinoma Of The Lung
- Inhibition Of Mclโ1 By Obatoclax Sensitizes Sp2/0โAg14 Hybridoma Cells To Glutamine DeprivationโInduced Apoptosis
- Inhibition Of Mcl-1 Enhances Cell Death Induced By The Bcl-2-Selective Inhibitor Abt-199 In Acute Myeloid Leukemia Cells
- Inhibition Of Mcl-1 Enhances Lapatinib Toxicity And Overcomes Lapatinib Resistance Via Bak-Dependent Autophagy
- Inhibition Of Mcl-1 Enhances Pevonedistat-Triggered Apoptosis In Osteosarcoma Cells
- Inhibition Of Mcl-1 Enhances The Efficacy Of Tyrosine Kinase Inhibition In Flt3 Mutated Aml And Synergizes With Venetoclax Targeting Aml Stem Cells
- Inhibition Of Mcl-1 Expression By Citrate Enhances The Effect Of Bcl-Xl Inhibitors On Human Ovarian Carcinoma Cells
- Inhibition Of Mcl-1 In Breast Cancer Cells Promotes Cell Death In Vitro And In Vivo
- Inhibition Of Mcl-1 In Mammary And Cns Tumor Cells Promotes Cell Death In Vitro And In Vivo
- Inhibition Of Mcl-1 Promotes Senescence In Cancer Cells: Implications For Preventing Tumor Growth And Chemotherapy Resistance
- Inhibition Of Mcl-1 Through Covalent Modification Of A Noncatalytic Lysine Side Chain
- Inhibition Of Mcl-1 With The PanโBcl-2 Family Inhibitor (โ) Bi97D6 Overcomes Abt-737 Resistance In Acute Myeloid Leukemia
- Inhibition Of Mir-302 Suppresses Hypoxia-Reoxygenation-Induced H9C2 Cardiomyocyte Death By Regulating Mcl-1 Expression
- Inhibition Of Nanog/Nanogp8 Downregulates Mcl-1 In Colorectal Cancer (Crc) Cells, Enhances The Efficacy Of Bh3 Mimetics And Inhibits Clonogenicity
- Inhibition Of Nanog/Nanogp8 Downregulates Mcl-1 In Colorectal Cancer Cells And Enhances The Therapeutic Efficacy Of Bh3 Mimetics
- Inhibition Of P38 ฮ Mapk Enhances Proteasome Inhibitor-Induced Apoptosis Of Myeloma Cells By Modulating Hsp27, Bcl-X L, Mcl-1 And P53 Levels In Vitro And โฆ
- Inhibition Of Polo Like Kinase 1 In Sarcomas Induces Apoptosis That Is Dependent On Mcl-1 Suppression
- Inhibition Of Pp2A Prevents Mcl-1 Dephosphorylation At The Thr-163/Ser-159 Phosphodegron, Dramatically Reducing Expression In Mcl-1-Amplified Lymphoma Cells
- Inhibition Of Proteasomal Degradation Of Mcl-1 By Cobalt Chloride Suppresses Cobalt Chloride-Induced Apoptosis In Hct116 Colorectal Cancer Cells
- Inhibition Of Protein Geranylgeranylation Induces Apoptosis In Myeloma Plasma Cells By Reducing Mcl-1 Protein Levels
- Inhibition Of Sphingosine Kinase 2 Downregulates The Expression Of C-Myc And Mcl-1 And Induces Apoptosis In Multiple Myeloma
- Inhibition Of Stat3 Signaling Leads To Apoptosis Of Leukemic Large Granular Lymphocytes And Decreased Mcl-1 Expression
- Inhibition Of Store-Operated Channels By Carboxyamidotriazole Sensitizes Ovarian Carcinoma Cells To Anti-Bclxl Strategies Through Mcl-1 Down-Regulation
- Inhibition Of Syk More Effectively Overcomes Mcl-1 Mediated Abt-199 Resistance Of Bcr-Stimulated Cll Cells Than Inhibition Of Btk Or Pi3Kdelta
- Inhibition Of The Jak-Stat3-Mcl-1 Axis By Combining Ruxolitinib With S63845 Completely Prevents Plasmacytoma Growth In The Gp130-Regulated Ina-6 Xenograft โฆ
- Inhibition Of The Mek1/2/Erk1/2 Pathway Sensitizes Human Leukemia Cells To Perifosine-Mediated Lethality Through A Jnk-, Akt-, And Mcl-1-Dependent Process
- Inhibition Of Two Gastric Cancer Cell Lines Induced By Fucoxanthin Involves Downregulation Of Mcl-1 And Stat3
- Inhibition Of Usp9X Deubiquitinase Activity By Wp1130 Reduces Mcl-1 Levels And Induces Apoptosis In Cells From Patients With Plasma Cell Dyscrasia And Drug-Refractory โฆ
- Inhibition Of Xpo 1 Enhances Cell Death Induced By Abtโ199 In Acute Myeloid Leukaemia Via Mclโ1
- Inhibition Sensitizes NonโSmall Cell Lung Cancer With T790M Mutation To Irreversible Egfr Inhibitors Via Translational Suppression Of Mcl-1 By Ampk Activation
- Inhibitor Celecoxib Can Suppress The Proliferation Of Flt3-Itd Positive Acute Myeloid Leukemia Cells With Prominent Down Regulation Of Mek/Mcl-1 Expression In Vitro
- Inhibitor Nvp-Bez235-Induced Apoptosis In Human Renal Carcinoma Caki Cells Through Down-Regulation Of P53-Dependent Bcl-2 Expression And Inhibition Of Mcl-1 โฆ
- Inhibitor Ym-155 Sensitizes Tumor Necrosis FactorโRelated Apoptosis-Inducing Ligand-Resistant Glioma Cells To Apoptosis Through Mcl-1 Downregulation And By โฆ
- Inhibitors Of The Antiapoptotic Myeloid Cell Leukemia-1 (Mcl-1) May Provide Effective Treatment For Cancer
- Inhibits Jak2 Transcription And Induces Apoptosis In Human Myeloproliferative Disorder Cells Bearing Jak2V617F Through Caspase-3-Mediated Cleavage Of Mcl-1
- Integrated Genomics Identifies Mir-32/Mcl-1 Pathway As A Critical Driver Of Melanomagenesis: Implications For Mir-Replacement And Combination Therapy
- Interactions Between Cancer-Associated Fibroblasts And Tumor Cells Promote Mcl-1 Dependency In Estrogen Receptor-Positive Breast Cancers
- Interferon ฮ Extends The Survival Of Human Myeloma Cells Through An Upregulation Of The Mclโ1 AntiโApoptotic Molecule
- Interleukin (Il)-7 Promotes T-Cell Survival By Stabilization Of Mcl-1
- Interleukin 15โMediated Survival Of Natural Killer Cells Is Determined By Interactions Among Bim, Noxa And Mcl-1
- Interleukin-13 In Combination With Cd40 Ligand Potently Inhibits Apoptosis In Human B Lymphocytes: Upregulation Of Bcl-Xl And Mcl-1
- Interleukinโ15 Delays Human Neutrophil Apoptosis By Intracellular Events And Not Via Extracellular Factors: Role Of Mclโ1 And Decreased Activity Of Caspaseโ3 And โฆ
- Interleukin-3 Stimulation Of Mcl-1 Gene Transcription Involves Activation Of The Pu. 1 Transcription Factor Through A P38 Mitogen-Activated Protein Kinase-Dependent โฆ
- Interleukin-6 Contributes To Mcl-1 Up-Regulation And Trail Resistance Via An Akt-Signaling Pathway In Cholangiocarcinoma Cells
- Interleukin-6 Expression Through Mapk/P38/Nf-ฮb Signaling Pathway And The Resultant Antiapoptotic Effect On Endothelial Cells Through Mcl-1 Expression With Sil6-Rฮฑ
- Interrelated Roles For Mcl-1 And Bim In Regulation Of Trail-Mediated Mitochondrial Apoptosis
- Intersection Of Mitochondrial Fission And Fusion Machinery With Apoptotic Pathways: Role Of Mclโ1
- Intracellular Targeting Of The Oncogenic Muc1-C Protein With A Go-203 Nanoparticle Formulation Overcomes Mcl-1-And Bfl-1-Mediated Resistance In Human โฆ
- Intracellular Zinc Release-Activated Erk-Dependent Gsk-3 ฮโP53 And NoxaโMcl-1 Signaling Are Both Involved In Cardiac Ischemic-Reperfusion Injury
- Intrinsic Resistance Of Prostate Cancer To The Bh3 Mimetic Abt-737 Is Related To Expression Of The Anti-Apoptotic Mcl-1 And Additional Survival And Apoptosis Regulating โฆ
- Introduction Of Constitutivelly Active Akt In Primary Cll B-Cells Results In Upregulation Of Mcl-1, Bcl-Xl And Cyclin D3 And Promotes Leukemic Cell Survival.
- Investigating The Functional Roles Of Mcl-1 In Apoptosis In Mammalian Cells
- Investigation Of The Role Of Mcl-1 And Mer In The Regulation Of Eosinophil Apoptosis And Efferocytosis
- In-Vitro Treatment Of Lymphoma Cell Lines With Bay 43-9006 (Sorafenib) Is Followed By Typical Features Of Apoptosis And Down-Regulation Of Mcl-1 Pointing To An โฆ
- Involvement Of Eat/Mcl-1, An Anti-Apoptotic Bcl-2-Related Gene, In Murine Embryogenesis And Human Development
- Ionizing Radiation Sensitizes Breast Cancer Cells To Bcl-2 Inhibitor, Abt-737, Through Regulating Mcl-1
- Ionizing Radiation-Inducible Microrna Mir-193A-3P Induces Apoptosis By Directly Targeting Mcl-1
- Ipnv Vp5, A Novel Anti-Apoptosis Gene Of The Bcl-2 Family, Regulates Mcl-1 And Viral Protein Expression
- Irinotecan Treatment And Senescence Failure Promote The Emergence Of More Transformed And Invasive Cells That Depend On Anti-Apoptotic Mcl-1
- Islet Cell Hyperplasia In Transgenic Mice Overexpressing Eat/Mcl-1, A Bcl-2 Related Gene
- Isolation And Identification Of Cyclic Polyketides From Endiandra Kingiana Gamble (Lauraceae), As Bcl-Xl/Bak And Mcl-1/Bid Dual Inhibitors, And Approaches Toward The โฆ
- Iterative Optimization Yields Mcl-1โTargeting Stapled Peptides With Selective Cytotoxicity To Mcl-1โDependent Cancer Cells
- Itraq-Based Quantitative Proteomic Analysis Of The Anti-Apoptotic Effect Of Hyperin, Which Is Mediated By Mcl-1 And Bid, In H2O2-Injured Ea. Hy926 Cells
- Jaceosidin Induces Apoptosis Through Bax Activation And Down-Regulation Of Mcl-1 And C-Flip Expression In Human Renal Carcinoma Caki Cells
- Jak2V617F Drives Mcl-1 Expression And Sensitizes Acute Myeloid Leukemia Cells To Dual Inhibition Of Jak2 And Bcl-Xl
- Jak2V617F Drives Mcl-1 Expression And Sensitizes Hematologic Cell Lines To Dual Inhibition Of Jak2 And Bcl-Xl
- Junduqing Extractive Promotes The Apoptosis Of Nasopharyngeal Carcinoma Cells Through Down-Regulating Mcl-1 And Bcl-Xl And Up-Regulating Caspase-3, Caspase-8 โฆ
- Juvenile Doxorubicin Treatment Impairs Recovery And Promotes Apoptosis In Adult Hearts Via Failure Of Up-Regulation Of Mcl-1 After Myocardial Infarction
- Key Survival Factor, Mcl-1, Correlates With Sensitivity To Combined Bcl-2/Bcl-Xl Blockade
- Kills Human Leukemia Cells Via Down-Regulation Of Mcl-1 Through A Transcriptional โฆ
- Kinase Axis Enhances Cytotoxic Effects Of Proteasome Inhibitors On Flt3-ItdโPositive Aml Cells By Cooperatively Inhibiting The Mtorc1/4Ebp1/S6K/Mcl-1 โฆ
- -Kinase Inhibtor Sorafenib Interacts Synergistically With The Hdac Inhibitor Vorinostat To Induce Apoptosis In Cml Cells In Association With Downregulation Of Mcl-1 โฆ
- Kingianins OโQ: Pentacyclic Polyketides From Endiandra Kingiana As Inhibitor Of Mcl-1/Bid Interaction
- Klf4 And Yy1 Are Resistant Factors In Nhl And Potential Therapeutic Targets: The New Resistant Nf-ฮb/Yy1/Klf4/Bclxl/Mcl-1 Axis
- Knee Joint Immobility Induces Mcl-1 Gene Expression In Articular Chondrocytes
- Knockdown Of Microrna-203 Alleviates Lps-Induced Injury By Targeting Mcl-1 In C28/I2 Chondrocytes
- Knockdown Of P53 Levels In Human Keratinocytes Accelerates Mcl-1 And Bcl-X L Reduction Thereby Enhancing Uv-Light Induced Apoptosis
- Knockdown Of The Foxm1 Enhances The Sensitivity Of Gastric Cancer Cells To Cisplatin By Targeting Mcl-1
- Kribb11 Accelerates Mcl-1 Degradation Through An Hsf1-Independent, Mule-Dependent Pathway In A549 Non-Small Cell Lung Cancer Cells
- Krรถhnke Pyridines: Rapid And Facile Access To Mcl-1 Inhibitors
- Lack Of Mcl-1 Confers Resistance To Bortezomid In Multiple Myeloma.
- Lactate Dehydrogenase 5 Expression In Melanoma Increases With Disease Progression And Is Associated With Expression Of Bcl-Xl And Mcl-1, But Not Bcl-2 โฆ
- Lana-1, Bcl-2, Mcl-1 And Hif-1ฮ Protein Expression In Hiv-Associated Kaposi Sarcoma
- Lapatinib And Obatoclax Kill Cns Tumor Cells Through Blockade Of Erbb1/3/4 And Through Inhibition Of Bcl-Xl And Mcl-1
- Lapatinib And Obatoclax Kill Tumor Cells Through Blockade Of Erbb1/3/4 And Through Inhibition Of Bcl-Xl And Mcl-1
- Lapatinib Resistance In Hct116 Cells Is Mediated By Elevated Mcl-1 Expression And Decreased Bak Activation And Not By Erbb Receptor Kinase Mutation
- Leishmania Donovani Exploits Myeloid Cell Leukemia 1 (Mcl-1) Protein To Prevent Mitochondria-Dependent Host Cell Apoptosis
- Leptin Stimulates Ovarian Cancer Cell Growth And Inhibits Apoptosis By Increasing Cyclin D1 And Mcl-1 Expression Via The Activation Of The Mek/Erk1/2 And Pi3K/Akt โฆ
- Leptin Stimulates Ovarian Cancer Cell Growth And Inhibits Apoptosis By Increasing Cyclin D1 And Mcl-1 Expression Via The Activation Of The Mek/Erk1/2 And โฆ
- Leptin Stimulates Ovarian Cancer Cell Growth And Inhibits Apoptosis By Increasing Cyclin D1 And Mcl-1 Expression Via The Activation Of The Mek/Erk1/2 โฆ
- Leptomycin B-Induced Apoptosis Is Mediated Through Caspase Activation And Down-Regulation Of Mcl-1 And Xiap Expression, But Not Through The Generation Of Ros In โฆ
- Leukaemia Inhibitory Factor Protects Cholangiocarcinoma Cells From Cytotoxicity Via A Stat-3-Independent, Mcl-1 Activation
- Leukemia Inhibitory Factor Protects Cholangiocarcinoma Cells From Drug-Induced Apoptosis Via A Pi3K/Akt-Dependent Mcl-1 Activation
- L-Gossypol Inhibits Nf-ฮb, Down Regulates Mcl-1 And Induces Apoptosis Of Primary Acute Myeloid Leukaemia Cells.
- Light Induced Apoptosis Is Accelerated In Transgenic Retina Overexpressing Human Eat/Mcl-1, An Anti-Apoptotic Bcl-2 Related Gene
- Lipidoid Nanoparticle Mediated Silencing Of Mcl-1 Induces Apoptosis In Mantle Cell Lymphoma
- Lipoic Acid Decreases Mcl-1, Bcl-X L And Up Regulates Bim On Ovarian Carcinoma Cells Leading To Cell Death
- Lncrna H19 Overexpression Induces Bortezomib Resistance In Multiple Myeloma By Targeting Mcl-1 Via Mir-29B-3P
- Lncrna Tug1 Contributes To Escc Progression Via Regulating Mirโ148Aโ3P/Mclโ1/Wnt/ฮโCatenin Axis In Vitro
- Long Noncoding Rna Itgb1 Promotes Migration And Invasion Of Clear Cell Renal Cell Carcinoma By Downregulating Mcl-1
- Long Noncoding Rna Linc00152 Promotes Cell Proliferation Through Competitively Binding Endogenous Mirโ125B With Mclโ1 By Regulating Mitochondrial Apoptosis โฆ
- Long NonโCoding Rna Myoslid Functions As A Competing Endogenous Rna To Regulate Mclโ1 Expression By Sponging Mirโ29Cโ3P In Gastric Cancer
- Long Noncoding Rna Pvt1 Inhibits Renal Cancer Cell Apoptosis By Up-Regulating Mcl-1
- Loss In Mcl-1 Function Sensitizes Non-Hodgkin’S Lymphoma Cell Lines To The Bcl-2-Selective Inhibitor Venetoclax (Abt-199)
- Loss Of A Single Mcl-1 Allele Inhibits Myc-Driven Lymphomagenesis By Sensitizing Pro-B Cells To Apoptosis
- Loss Of Mcl-1 Leads To Impaired Autophagy And Rapid Development Of Heart Failure
- Loss Of Mcl-1 Protein And Inhibition Of
- Loss Of Mcl-1 Protein And Inhibition Of Electron Transport Chain Together Induce Anoxic Cell Death
- Loss Of P53 And Altered Mir15-A/16-1๎ฒMcl-1 Pathway In Cll: Insights From Tcl1-Tg:P53โ/โ Mouse Model And Primary Human Leukemia Cells
- Loss Of Pkcฮด Induces Prostate Cancer Resistance To Paclitaxel Through Activation Of Wnt/ฮ-Catenin Pathway And Mcl-1 Accumulation
- Low Affinity Interaction With Cll B-Cell Receptors Induces Apoptosis By Down-Regulating Mcl-1 And Up-Regulating Bimel.
- Low Carbohydrate Diet Prevents Mcl-1-Mediated Resistance To Bh3-Mimetics
- Low Human And Murine Mcl-1 Expression Leads To A Pro-Apoptotic Plaque Phenotype Enriched In Giant-Cells
- Low Mcl-1 Mrna Expression Correlates With Prolonged Survival In B-Cell Chronic Lymphocytic Leukemia
- Low-Dose Actinomycin D Decreases Mcl-1 Expression And Acts Synergistically With Abt-737 To Induce Apoptosis Of Sclc Cell Lines
- LowโMolecularโMass Hyaluronan Induces Pulmonary Inflammation By UpโRegulation Of Mclโ1 To Inhibit Neutrophil Apoptosis Via Pi 3K/Akt1 Pathway
- Lycorine Induces Apoptosis And Down-Regulation Of Mcl-1 In Human Leukemia Cells
- Lysophosphatidic Acid Induces Upregulation Of Mcl-1 And Protects Apoptosis In A Ptx-Dependent Manner In H19-7 Cells
- M. Leprae Inhibits Apoptosis In Thp-1 Cells By Downregulation Of Bad And Bak And Upregulation Of Mcl-1 Gene Expression
- M2I-1 Disrupts The In Vivo Interaction Between Cdc20 And Mad2 And Increases The Sensitivities Of Cancer Cell Lines To Anti-Mitotic Drugs Via Mcl-1S
- Ma27. 09 Dual Inhibition Of Bcl-Xl And Mcl-1 Is Required To Induce Tumour Regression In Lung Squamous Cell Carcinomas Sensitive To Fgfr Inhibition
- Macc1 Regulates Death Receptor Mediated Apoptosis In Solid Cancers Through Stat1/3โMcl-1 Signaling
- Macc1 Regulates Fas Mediated Apoptosis Through Stat1/3โMcl-1 Signaling In Solid Cancers
- Macrophages Confer Survival Signals Via Ccr1-Dependent Translational Mcl-1 Induction In Chronic Lymphocytic Leukemia
- Magnolin Promotes Autophagy And Cell Cycle Arrest Via Blocking Lif/Stat3/Mcl-1 Axis In Human Colorectal Cancers
- Male Sterility In Mcl-1-Flox Mice Is Not Due To Enhanced Mcl1 Protein Stability
- Mapk P38 And Jnk Have Opposing Activities On Trail-Induced Apoptosis Activation In Nsclc H460 Cells That Involves Rip1 And Caspase-8 And Is Mediated By Mcl-1
- Mapk/P38/Nf-Kb Signaling Pathway For Radiation Increased Il-6 Expression Of Endothelial Cells With Anti-Apoptosis Effect Through Mcl-1
- Mapping The Bh3 Binding Interface Of Bcl-Xl, Bcl-2, And Mcl-1 Using Split-Luciferase Reassembly
- Marinopyrrole Derivatives With Sulfide Spacers As Selective Disruptors Of Mcl-1 Binding To Pro-Apoptotic Protein Bim
- Maritoclax And Dinaciclib Inhibit Mcl-1 Activity And Induce Apoptosis In Both A Mcl-1-Dependent And-Independent Manner
- Maritoclax Induces Apoptosis In Acute Myeloid Leukemia Cells With Elevated Mcl-1 Expression
- Maritoclax, A Selective Mcl-1 Inhibitor, Sensitizes Melanoma Cells To The Bad Bh3-Mimetic Abt-737.
- Mbp-1 Upregulates Mir-29B, Which Represses Mcl-1, Collagens, And Matrix Metalloproteinase-2 In Prostate Cancer Cells
- Mcl-1
- Mcl-1 And Bax In The Fetal Ovary: Studies Of The Undernourished Pregnant Ewe
- Mcl-1 And Bcl-2 Expression In Neuroendocrine Carcinoma (Nec) And Potential For New Therapeutic Target.
- Mclโ1 And Bclโ2/Bax Ratio Are Associated With Treatment Response But Not With Rai Stage In BโCell Chronic Lymphocytic Leukemia
- Mcl-1 And Bcl-X L Sequestration Of Bak Confers Differential Resistance To Bh3-Only Proteins
- Mclโ1 And BclโXl Are CoโRegulated By Ilโ6 In Human Myeloma Cells
- Mcl-1 And Bcl-Xl Are Essential For Survival Of The Developing Nervous System
- Mclโ1 And BclโXl Cooperatively Maintain Integrity Of Hepatocytes In Developing And Adult Murine Liver
- Mcl-1 And Bcl-Xl Coordinately Regulate Megakaryocyte Survival
- Mcl-1 And Bcl-Xl Regulate Bak/Bax-Dependent Apoptosis Of The Megakaryocytic Lineage At Multistages
- Mcl-1 And Bcl-Xl-Dependent Resistance To The Bcl-2 Inhibitor Abt-199 Can Be Overcome By Preventing Pi3K/Akt/Mtor Activation In Lymphoid โฆ
- Mcl-1 And Fbw7 Control A Dominant Survival Pathway Underlying Hdac And Bcl-2 Inhibitor Synergy In Squamous Cell Carcinoma
- Mcl-1 And Its Role In Cancer Research
- Mcl-1 And Mir-181C In Gata2 Mutation Associated Monomac And Familial Myelodysplastic Syndrome
- Mcl-1 And Pka/Ampk Axis Fuel Venetoclax Resistance In Lymphoid Cancers
- Mcl-1 And Tumor Cell Persistence
- Mcl-1 And Vdac Interaction Promotes Mitochondrial Ca2+ Uptake And Ros Production (1159.12)
- Mcl-1 And Yy1 Inhibition And Induction Of Dr5 By The Bh3-Mimetic Obatoclax (Gx15-070) Contribute In The Sensitization Of B-Nhl Cells To Trail Apoptosis
- Mcl-1 Antagonism Enhances The Anti-Invasive Effects Of Dasatinib In Pancreatic Adenocarcinoma
- Mcl-1 Antagonism Is A Potential Therapeutic Strategy In A Subset Of Solid Cancers
- Mcl-1 Antagonizes Bax/Bak To Promote Effector Cd4+ And Cd8+ T-Cell Responses
- Mcl-1 Antisense Therapy Chemosensitizes Human Melanoma In A Scid Mouse Xenotransplantation Model
- Mcl-1 As A Buffer For Proapoptotic Bcl-2 Family Members During Trail-Induced Apoptosis A Mechanistic Basis For Sorafenib (Bay 43-9006)-Induced โฆ
- Mcl-1 As A Possible Predictor Of Progression-Free Survival In Previously Untreated Chronic Lymphocytic Leukemia Patients Treated With Pentostatin โฆ
- Mcl-1 As A Potential Therapeutic Target For Human Hepatocelluar Carcinoma
- Mcl-1 As A Therapeutic Target In Acute Myelogenous Leukemia (Aml)
- Mcl-1 Attenuates Vinblastine-Induced Apoptosis In Ml-1 Leukemia Cells
- Mcl-1 Blocks Radiation-Induced Apoptosis And Inhibits Clonogenic Cell Death
- Mcl-1 But Not Bcl-Xl Is Critical For The Development And Sustained Expansion Of Thymic Lymphoma In P53-Deficient Mice
- Mcl-1 Cleavage And Sustained Phosphorylation Of C-Jun-N-Terminal Kinase Mediate Melanoma Apoptosis Induced By 2-Acetyl Furanonaphthoquinone: Roles Of Bcl-2 โฆ
- Mcl-1 Confers Protection Of Her2-Positive Breast Cancer Cells To Hypoxia: Therapeutic Implications
- Mcl-1 Correlates With Reduced Apoptosis In Neutrophils From Patients With Sepsis
- Mcl-1 Couples Mitochondrial Dynamic Machinery To Mitochondrial Quality Control In Response To Stress
- Mcl-1 Critically Regulates Survival Of T-Lymphocyte Non-Hodgkin Lymphoma
- Mcl-1 Deficiency Results In Peri-Implantation Embryonic Lethality
- Mcl-1 Degradation During Hepatocyte Lipoapoptosis
- Mcl-1 Degradation Is Required For Targeted Therapeutics To Eradicate Colon Cancer Cells
- Mcl-1 Degradation Mediated By Jnk Activation Via Mekk1/Tak1-Mkk4
- Mcl-1 Degradation Mediated By Jnk Activation Via Mekk1/Tak1-Mkk4 Contributes To Anticancer Activity Of New Tubulin Inhibitor Mt189
- Mcl-1 Dependence Predicts Response To Vorinostat And Gemtuzumab Ozogamicin In Acute Myeloid Leukemia
- Mcl-1 Dependency Is A Predictive Biomarker For Apoptotic Induction By Short-Term Dinaciclib (Sch 727965) Treatment
- Mcl-1 Dependency Of Cisplatin-Resistant Cancer Cells
- Mcl-1 Depletion Impairs Dna Double-Strand Break Repair And Reinitiation Of Stalled Dna Replication Forks
- Mcl-1 Depletion In Apoptosis Elicited By Ionizing Radiation In Peritoneal Resident Macrophages Of C3H Mice
- Mcl-1 Depletion Sensitizes The Apoptosis Of Gastrointestinal Cancer Cells Mediated By Anti-Cancer Drugs.
- Mcl-1 Determines The Bax Dependency Of Nbk/Bik-Induced Apoptosis
- Mcl-1 Determines The Imiquimod-Induced Apoptosis But Not Imiquimod-Induced Autophagy In Skin Cancer Cells
- Mcl-1 Dictates Dna Double-Strand Break Repair Pathway Choice
- Mcl-1 Downregulation By Pro-Inflammatory Cytokines And Palmitate Is An Early Event Contributing Beta Cell Apoptosis.
- Mcl-1 Downregulation By Pro-Inflammatory Cytokines And Palmitate Is An Early Event Contributing To ฮ-Cell Apoptosis
- Mcl-1 Downregulation By Ym155 Contributes To Its Synergistic Anti-Tumor Activities With Abt-263
- Mcl-1 Downregulation Leads To The Heightened Sensitivity Exhibited By Bcr-Abl Positive All To Induction Of Energy And Er-Stress
- Mcl-1 Downregulation Plays A Crucial Role In The Synergistic Anticancer Activities Between Pi-3 Kinase Inhibitors And Histone Deacetylase Inhibitors In Primary Nsclc โฆ
- Mcl-1 Down-Regulation Potentiates Abt-737 Lethality By Cooperatively Inducing Bak Activation And Bax Translocation
- Mcl-1 Downregulation Sensitizes Glioma To Bortezomib-Induced Apoptosis
- Mcl-1 Drives Resistance Of Estrogen Receptor-[Alpha] Positive Breast Cancers To Targeted Therapies
- Mcl-1 Dynamics Influence Mitotic Slippage And Death In Mitosis
- Mcl-1 Expression And Jnk Activation Induces A Threshold For Apoptosis In Bcl-Xl-Overexpressing Hematopoietic Cells
- Mcl-1 Expression Has In Vitro And In Vivo Significance In Chronic Lymphocytic Leukemia And Is Associated With Other Poor Prognostic Markers
- Mcl-1 Expression In B-Cell Non-Hodgkin’S Lymphomas
- Mclโ1 Expression In Gestational Trophoblastic Disease Correlates With Clinical Outcome: A Differential Expression Study
- Mcl-1 Expression In Human Neutrophils: Regulation By Cytokines And Correlation With Cell Survival
- Mcl-1 Expression Influcences Cd8+ Anti-Tumor Immunity.
- Mcl-1 Expression Is Up-Regulated In Malignancies Of The Parotid Gland
- Mcl-1 Expression Of Non-Small Cell Lung Cancer As A Prognostic Factor And Mcl-1 As A Promising Target For Gene Therapy.
- Mcl-1 Expression Predicts Progression-Free Survival In Chronic Lymphocytic Leukemia Patients Treated With Pentostatin, Cyclophosphamide, And Rituximab
- Mcl-1 Facilitates Mitochondrial Fission And Clearance
- Mcl-1 Facilitates The Removal Of Damaged Mitochondria Via The Mitophagy Receptor Bnip3
- Mcl-1 Fragment Mcl-1 (128โ350) Induces Inhibition Of Multiple Myeloma Cell Proliferation And Apoptosis Via Both Upregulation Of C-Jun As Well As Modulation Of Its โฆ
- Mcl-1 Functions As Major Epidermal Survival Protein Required For Proper Keratinocyte Differentiation
- Mcl-1 Gene And Hepatocellular Carcinoma [J]
- Mcl-1 Gene And Its Role In Leukemia [J]
- Mcl-1 Gene Promoter Insertions Do Not Correlate With Disease Outcome, Stage Or Vh Gene Mutation Status In Chronic Lymphocytic Leukaemia
- Mcl-1 In Breast Cancer: Regulation By The Egf Receptor Family And Role In Cell Survival And Drug Resistance
- Mcl-1 In Transgenic Mice Promotes Survival In A Spectrum Of Hematopoietic Cell Types And Immortalization In The Myeloid Lineage
- Mcl-1 Inhibition Ameliorates The Expansion Of Human Leukemia In A Dose Dependent Fashion
- Mcl-1 Inhibition By Selective Bh3 Mimetics Disrupts Mitochondrial Dynamics In Ipsc-Derived Cardiomyocytes
- Mcl-1 Inhibition By The Selective Mcl-1 Inhibitor Amg-176 Induces In Vitro Activity Against Burkitt Lymphoma Cell Lines And Synergistically Enhances The Cytotoxic โฆ
- Mcl-1 Inhibition In Cancer Treatment
- Mcl-1 Inhibition Provides A New Way To Suppress Breast Cancer Metastasis And Increase Sensitivity To Dasatinib
- Mcl-1 Inhibitor Induces Cells Death In Braf-Mutant Amelanotic Melanoma Trough Gsh Depletion, Dna Damage And Cell Cycle Changes
- Mcl-1 Inhibitor Suppresses Tumor Growth Of Esophageal Squamous Cell Carcinoma In A Mouse Model
- Mcl-1 Inhibitor-Induced Killing Of Multiple Myeloma Is Modulated By The Relative Level Of Expression Of Pro-Survival Members Of The Bcl-2 Family And The Proto โฆ
- Mcl-1 Inhibitors For The Treatment Of Cancer
- Mcl-1 Inhibitors: A Patent Review
- Mcl-1 InhibitorsโWhere Are We Now (2019)?
- Mcl-1 Inhibits Bax In The Absence Of Mcl-1/Bax Interaction
- Mcl-1 Inhibits Mff-Mediated Mitochondrial Fragmentation And Apoptosis
- Mcl-1 Integrates The Opposing Actions Of Signaling Pathways That Mediate Survival And Apoptosis
- Mcl-1 Interacts With Akt To Promote Lung Cancer Progression
- Mcl-1 Interacts With Truncated Bid And Inhibits Its Induction Of Cytochrome C Release And Its Role In Receptor-Mediated Apoptosis
- Mcl-1 Inversely Correlates With Gsk-3ฮ Activity And Associates With Poor Prognosis In Human Breast Cancer
- Mcl-1 Involvement In Mitochondrial Dynamics Is Associated With Apoptotic Cell Death
- Mcl-1 Involves In G_2/M Arrest Of Hl-60 Cells Induced By Diallyl Disulfide
- Mcl-1 Is A Common Target Of Stem Cell Factor And Interleukin-5 For Apoptosis Prevention Activity Via Mek/Mapk And Pi-3K/Akt Pathways
- Mcl-1 Is A Critical Survival Factor In Neural Precursor Cells Of The Adult Mammalian Brain
- Mcl-1 Is A Gate Keeper Regulating Cell Death In Cancer Cells
- Mcl-1 Is A Key Antiapoptotic Protein In Human And Rodent Pancreatic ฮ-Cells
- Mcl-1 Is A Key Anti-Apoptotic Protein In Human And Rodent Pancreatic ฮ-Cells
- Mcl-1 Is A Key Determinant Of Breast Cancer Cell Survival: Validation Of Mcl-1 Dependency Utilizing A Highly Selective Small Molecule Inhibitor
- Mcl-1 Is A Key Regulator Of Apoptosis During Cns Development And After Dna Damage
- Mcl-1 Is A Key Regulator Of Apoptosis In Neural Precursor Cells And Autophagy In Post-Mitotic Neurons
- Mcl-1 Is A Key Regulator Of Apoptosis Resistance In Chlamydia Trachomatis-Infected Cells
- Mcl-1 Is A Key Regulator Of The Ovarian Reserve
- Mcl-1 Is A Novel Target Of Mir-26B That Is Associated With The Apoptosis Induced By Trail In Hcc Cells
- Mcl-1 Is A Novel Therapeutic Target For Human Sarcoma: Synergistic Inhibition Of Human Sarcoma Xenotransplants By A Combination Of Mcl-1 Antisense Oligonucleotides โฆ
- Mcl-1 Is A Potential Therapeutic Target In Multiple Types Of Cancer
- Mcl-1 Is A Prognostic Indicator And Drug Target In Breast Cancer
- Mcl-1 Is A Relevant Molecular Target For Antisense Oligonucleotide Strategies In Gastric Cancer Cells
- Mcl-1 Is A Relevant Therapeutic Target In Acute And Chronic Lymphoid Malignancies: Down-Regulation Enhances Rituximab-Mediated Apoptosis And Complement โฆ
- Mcl-1 Is A Stress Sensor That Regulates Autophagy In A Developmentally Regulated Fashion
- Mclโ1 Is A Stress Sensor That Regulates Autophagy In A Developmentally Regulated Manner
- Mcl-1 Is An Anti-Apoptotic Factor For Human Hepatocellular Carcinoma
- Mcl-1 Is An Immediate-Early Gene Activated By The Granulocyte-Macrophage Colony-Stimulating Factor (Gm-Csf) Signaling Pathway And Is One Component Of The Gm โฆ
- Mcl-1 Is An Important Determinant Of The Apoptotic Response To The Bh3-Mimetic Molecule Ha14-1 In Cisplatin-Resistant Ovarian Carcinoma Cells
- Mcl-1 Is An Important Therapeutic Target For Oral Squamous Cell Carcinomas
- Mcl-1 Is Critical For Survival In A Subgroup Of Non-Small-Cell Lung Cancer Cell Lines
- Mcl-1 Is Differentially Regulated In Acute Myeloid Leukemia Cells Treated With All Trans Retinoic Acid And Arsenic Trioxide
- Mcl-1 Is Downregulated In Cisplatin-Induced Apoptosis, And Proteasome Inhibitors Restore Mcl-1 And Promote Survival In Renal Tubular Epithelial Cells
- Mcl-1 Is Essential For Germinal Center Formation And B Cell Memory
- Mcl-1 Is Essential For Myocardial Homeostasis And Autophagy
- Mcl-1 Is Essential For The Survival Of Plasma Cells
- Mcl-1 Is Essential For The Survival Of Synovial Fibroblasts In Rheumatoid Arthritis
- Mcl-1 Is Important For Integrity And Survival Of Hepatocytes
- Mcl-1 Is Modulated In Crohn’S Disease Fibrosis By Mir-29B Via Il-6 And Il-8
- Mcl-1 Is Overexpressed In Multiple Myeloma And Associated With Relapse And Shorter Survival
- Mcl-1 Is Overexpressed In Multiple Myeloma And Correlates With Disease Severity.
- Mcl-1 Is Regulated By Il-6 And Mediates The Survival Activity Of The Cytokine In A Model Of Late Stage Prostate Carcinoma
- Mcl-1 Is Required For Akata6 B-Lymphoma Cell Survival And Is Converted To A Cell Death Molecule By Efficient Caspase-Mediated Cleavage
- Mcl-1 Is Required For Melanoma Cell Resistance To Anoikis
- Mcl-1 Is Required Throughout B-Cell Development And Its Loss Sensitizes Specific B-Cell Subsets To Inhibition Of Bcl-2 Or Bcl-Xl
- Mcl-1 Is The Key Target Of Adjuvant Chemotherapy To Reverse The Cisplatin-Resistance In Nsclc
- Mcl-1 Is Vital For Neutrophil Survival
- Mcl-1 Keeps A Charming Home For Thymocytes
- Mcl-1 Levels Need Not Be Lowered For Cells To Be Sensitized For Abt-263/737-Induced Apoptosis
- Mcl-1 Localizes To Sites Of Dna Damage And Regulates Dna Damage Response
- Mcl-1 Mediates Cytokine Deprivation Induced Apoptosis Of Human Myeloma Cell Line Xg-7.
- Mcl-1 Mediates Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand Resistance In Human Cholangiocarcinoma Cells
- Mcl-1 Mediates Tweak/Fn14-Induced NonโSmall Cell Lung Cancer Survival And Therapeutic Response
- Mcl-1 Or Bcl-Xl-Dependent Resistance To The Bcl-2 Antagonist (Abt-199) Can Be Overcome By Specific Inhibitor As Single Agents And In Combination With Abt-199 In โฆ
- Mcl-1 Overexpression In Hepatocellular Carcinoma: A Potential Target For Antisense Therapy
- Mclโ1 Overexpression Leads To Higher Viabilities And Increased Production Of Humanized Monoclonal Antibody In Chinese Hamster Ovary Cells
- Mcl-1 Phosphorylation Defines Abt-737 Resistance That Can Be Overcome By Increased Noxa Expression In Leukemic B Cells
- Mcl-1 Phosphorylation Without Degradation Mediates Sensitivity To Hdac Inhibitors By Liberating Bh3-Only Proteins
- Mcl-1 Promoter Insertions As An Independent Prognostic Factor For Treatment Free Survival In Chronic Lymphocytic Leukaemia.
- Mcl-1 Promoter Insertions Dial-Up Aggressiveness Of Chronic Leukemia
- Mcl-1 Promotes Drp1-Mediated Mitochondrial Fission As An Adaptive Response To Stress
- Mclโ1 Promotes Drug Resistance In Pancreatic Cancer Cells
- Mcl-1 Promotes Lung Cancer Cell Migration By Directly Interacting With Vdac To Increase Mitochondrial Ca 2+ Uptake And Reactive Oxygen Species Generation
- Mcl-1 Promotes Mitochondrial Fusion And Survival In Cardiac Myocytes
- Mcl-1 Promotes Neural Precursor Cell Cycle Exit And Differentiation In The Mouse Embryonic Brain
- Mcl-1 Promotes Survival And Influences Mitochondrial Dynamics In Cardiac Myocytes
- Mcl-1 Promotes Survival Of Thymocytes By Inhibition Of Bak In A Pathway Separate From Bcl-2
- Mcl-1 Promotes T Cell Survival Independently Of Bcl-2 Through Interaction With Bak (84.19)
- Mcl-1 Protects Prostate Cancer Cells From Cell Death Mediated By Chemotherapy-Induced Dna Damage
- Mcl-1 Protects Prostate Cancer Cells From Chemotherapy-Induced Dna Damage
- Mcl-1 Quadruplex Nucleic Acids And Uses Thereof
- Mcl-1 Reduction: Releasing A Death Brake?
- Mcl-1 Regulates Effector And Memory Cd8 T-Cell Differentiation During Acute Viral Infection
- Mcl-1 Regulates Mitochondrial Dynamics And Mitophagy
- Mcl-1 Regulates Mitochondrial Fission And Mitophagy
- Mcl-1 Regulates Reactive Oxygen Species Via Nox4 During Chemotherapy-Induced Senescence
- Mcl-1 Regulates Survival And Sensitivity To Diverse Apoptotic Stimuli In Human Non-Small Cell Lung Cancer Cells
- Mcl-1 Regulates The Balance Between Autophagy And Apoptosis
- Mcl-1 Regulates The Survival Of Adult Neural Precursor Cells
- Mcl-1 Regulation And Its Role In Multiple Myeloma
- Mcl-1 Rescues A Glitch In The Matrix
- Mcl-1 Sequesters Pro-Apoptotic Bh3-Only Bim To Inhibit Its Collaboration With Bax In Myeloma Cells.
- Mcl-1 Signals Pathway Inhibitors In Mouse Peritoneal Macrophage Apoptosis Infected With The Xinjiang Strain Of M. Tuberculosis
- Mcl-1 Small-Molecule Inhibitors Encapsulated Into Nanoparticles Exhibit Increased Killing Efficacy Towards Hcmv-Infected Monocytes
- Mcl-1 Stability Determines Mitotic Cell Fate Of Human Multiple Myeloma Tumor Cells Treated With The Kinesin Spindle Protein Inhibitor Arry-520
- Mcl-1 Stabilization Confers Resistance To Taxol In Human Gastric Cancer
- Mcl-1 Structural Dynamics From Protein Ensembles, Enhanced Sampling And Pocket Crosstalk Analysis.
- Mcl-1 Suppresses Abasic Site Repair Following Bile AcidโInduced Hepatic Cellular Dna Damage
- Mcl-1 Suppression Sensitizes Kras-Mutant Crc To Bcl-2/Bcl-Xl Inhibition
- Mclโ1 Targeting Could Be An Intriguing Perspective To Cure Cancer
- Mcl-1 Ubiquitination And Destruction
- Mcl-1 Ubiquitination: Unique Regulation Of An Essential Survival Protein
- Mcl-1 Up-Regulation Through Mapk Activation Confers Acquired Resistance To Bcl-2 Inhibitor Abt-199 In Pre-Clinical Aml Models
- Mcl-1, A Bcl-2 Family Member, Delays The Death Of Hematopoietic Cells Under A Variety Of Apoptosis-Inducing Conditions
- Mcl-1, A Member Of The Bcl-2 Family, Delays Apoptosis Induced By C-Myc Overexpression In Chinese Hamster Ovary Cells
- Mclโ1, A Member Of The Bclโ2 Family, Is Induced Rapidly In Response To Signals For Cell Differentiation Or Death, But Not To Signals For Cell Proliferation
- Mcl-1, A Novel Target Gene Of Foxm1, Is Negatively Associated With Sensitivity To Oxaliplatin In Gastric Cancer
- Mcl-1, An Anti-Apoptotic Bcl-2 Family Member, Essentially Overlaps With Insulin-Producing Cells In Neonatal Nesidioblastosis
- Mcl-1, An Early-Induction Molecule, Modulates Activin A-Induced Apoptosis And Differentiation Of Cml Cells
- Mcl-1, Bcl-Xl And Cell Cycle Inhibition By Gcs-100: A Novel Therapy For Myeloma.
- Mcl-1, Bcl-Xl And Mitf Are Diversely Employed In Adaptive Response Of Melanoma Cells To Changes In Microenvironment
- Mcl-1, Bcl-Xl And Stat3 Expression Are Associated With Progression Of Melanoma Whereas Bcl-2, Ap-2 And Mitf Levels Decrease During Progression Of โฆ
- Mcl-1, Vascular Endothelial Growth Factor-R2, And 14-3-3ฮฃ Expression Might Predict Primary Response Against Radiotherapy And Chemotherapy In Patients With Locally โฆ
- Mcl-1, Which Can Prevent Leukemia Cell Death, Is Necessary For Bone Marrow Stem Cell Survival
- Mcl-1/Cdk9 Targeting By Azd5991/Azd4573 Overcomes Intrinsic And Acquired Venetoclax Resistance In Vitro And In Vivo In Pdx Model Of Aml Through โฆ
- Mcl-1: A Gateway To Trail Sensitization
- Mcl-1: A Highly Regulated Cell Death And Survival Controller
- Mcl-1: The 1 In Cll
- Mclโ1; The Molecular Regulation Of Protein Function
- Mclโ1โBim Complexes Accommodate Surprising Point Mutations Via Minor Structural Changes
- Mcl-1-Dependent Activation Of Beclin 1 Mediates Autophagic Cell Death Induced By Sorafenib And Sc-59 In Hepatocellular Carcinoma Cells
- Mcl-1โDependent Leukemia Cells Are More Sensitive To Chemotherapy Than Bcl-2โDependent Counterparts
- Mcl-1Es, A Novel Variant Of Mcl-1, Associates With Mcl-1L And Induces Mitochondrial Cell Death
- Mcl-1-Guardian Of The Ovarian Reserve: Characterization Of The Contribution Of Mcl-1 To Oocyte Survival
- Mcl-1-Independent Mechanisms Of Synergy Between Dual Pi3K/Mtor And Bcl-2 Inhibition In Diffuse Large B Cell Lymphoma
- Mcl-1โJust Another Antiapoptotic Bcl-2 Homolog?
- Mcl-1-Mediated Impairment Of The Intrinsic Apoptosis Pathway In Circulating Neutrophils From Critically Ill Patients Can Be Overcome By Fas Stimulation
- Mcl-1-Mediated Resistance To Abt-263 Is Combated By Mtor Inhibition In Luminal Breast Cancers
- Mcl-1S, A Splicing Variant Of The Antiapoptotic Bcl-2 Family Member Mcl-1, Encodes A Proapoptotic Protein Possessing Only The Bh3 Domain
- Mcl-1V, A Novel Mouse Antiapoptotic Mcl-1 Variant, Generated By Rna Splicing At A Non-Canonical Splicing Pair
- Mechanism And Functional Role Of Xiap And Mcl-1 Down-Regulation In Flavopiridol/Vorinostat Antileukemic Interactions
- Mechanism By Which Mcl-1 Regulates Cancer-Specific Apoptosis Triggered By Mda-7/Il-24, An Il-10โRelated Cytokine
- Mechanism Of Apoptosis Induced By Mcl-1 Inhibitor Umi-77 On Gallbladder Carcinoma Gbc-Sd Cells
- Mechanism Of Mclโ1 Conformational Regulation Upon Small Molecule Binding Revealed By Molecular Dynamic Simulation
- Mechanism Of Synergy Of Bh3 Mimetics And Paclitaxel In Chronic Myeloid Leukemia Cells: Mcl-1 Inhibition
- Mechanism Of Synergy Of N-(4-Hydroxyphenyl)Retinamide And Abt-737 In Acute Lymphoblastic Leukemia Cell Lines: Mcl-1 Inactivation
- Mechanisms Involved In Interleukinโ15โInduced Suppression Of Human Neutrophil Apoptosis: Role Of The AntiโApoptotic Mclโ1 Protein And Several Kinases Including โฆ
- Mechanisms Of EthanolโMediated Colorectal Carcinogenesis: The Role Of Cytochrome P4502E1, EthenoโDna Adducts, And The AntiโApoptotic Protein Mclโ1
- Mek Inhibition Enhances Abt-737-Induced Leukemia Cell Apoptosis Via Prevention Of Erk-Activated Mcl-1 Induction And Modulation Of Mcl-1/Bim Complex
- Mek/Erk And Mcl-1 Inhibition Synergistically Reverse Apoptosis Resistance In Colon Cancer Cells With Braf (V600E)-Mediated Mcl-1-Upregulation
- Mek/Erk Signaling Pathway Regulates The Expression Of Bclโ2, BclโXl, And Mclโ1 And Promotes Survival Of Human Pancreatic Cancer Cells
- Melphalan-Induced Apoptosis In Multiple Myeloma Cells Is Associated With A Cleavage Of Mcl-1 And Bim And A Decrease In The Mcl-1/Bim Complex
- Membrane Expression Of Dr4, Dr5 And Caspase-8 Levels, But Not Mcl-1, Determine Sensitivity Of Human Myeloma Cells To Apo2L/Trail
- Mesothelin Confers Pancreatic Cancer Cell Resistance To Tnf-ฮ-Induced Apoptosis Through Akt/Pi3K/Nf-ฮb Activation And Il-6/Mcl-1 Overexpression
- Metformin Combined With Aspirin Significantly Inhibit Pancreatic Cancer Cell Growth In Vitro And In Vivo By Suppressing Anti-Apoptotic Proteins Mcl-1 And Bcl-2
- Metformin Combined With Sodium Dichloroacetate Promotes B Leukemic Cell Death By Suppressing Anti-Apoptotic Protein Mcl-1
- Metformin Enhances Trail-Induced Apoptosis By Mcl-1 Degradation Via Mule In Colorectal Cancer Cells
- Metformin Requires 4E-Bps To Induce Apoptosis And Repress Translation Of Mcl-1 In Hepatocellular Carcinoma Cells
- Methylseleninic Acid Potentiates Multiple Types Of Cancer Cells To Abt-737-Induced Apoptosis By Targeting Mcl-1 And Bad
- Methylseleninic Acid Potentiates Multiple Types Of Cancer Cells To Abt-737-Induced Apoptosis Involving Mcl-1, Akt-Bad, And Mitochondrial Cascade
- Microrna 133B Targets Pro-Survival Molecules Mcl-1 And Bcl2L2 In Lung Cancer
- Microrna 17โ5P Regulates Autophagy In Mycobacterium TuberculosisโInfected Macrophages By Targeting Mclโ1 And Stat3
- Microrna Hsa-Mir-29B Potentiates Etoposide Toxicity In Hela Cells Via Down-Regulation Of Mcl-1
- Microrna-101 Inhibits Cell Progression And Increases Paclitaxel Sensitivity By Suppressing Mcl-1 Expression In Human Triple-Negative Breast Cancer
- Microrna-101 Sensitizes Hepatocellular Carcinoma Cells To Doxorubicin-Induced Apoptosis Via Targeting Mcl-1
- Microrna-101 Targets Ezh2, Mcl-1 And Fos To Suppress Proliferation, Invasion And Stem Cell-Like Phenotype Of Aggressive Endometrial Cancer Cells
- Micrornaโ105 Promotes EpithelialโMesenchymal Transition Of Nonsmall Lung Cancer Cells Through Upregulating Mclโ1
- Microrna-125B Promotes Apoptosis By Regulating The Expression Of Mcl-1, Bcl-W And Il-6R
- Microrna-133A, Downregulated In Osteosarcoma, Suppresses Proliferation And Promotes Apoptosis By Targeting Bcl-Xl And Mcl-1
- Microrna-193B-3P Represses Neuroblastoma Cell Growth Via Downregulation Of Cyclin D1, Mcl-1 And Mycn
- Microrna-30 Inhibits Antiapoptotic Factor Mcl-1 In Mouse And Human Hematopoietic Cells After Radiation Exposure
- Microrna-302B Enhances The Sensitivity Of Hepatocellular Carcinoma Cell Lines To 5-Fu Via Targeting Mcl-1 And Dpyd
- Microrna-302B Targets Mcl-1 And Inhibits Cell Proliferation And Induces Apoptosis In Malignant Pleural Mesothelioma Cells
- Microrna-451 Sensitizes Lung Cancer Cells To Cisplatin Through Regulation Of Mcl-1
- Mik665/S64315, A Novel Mcl-1 Inhibitor, In Combination With Bcl-2 Inhibitors Exhibits Strong Synergistic Antitumor Activity In A Range Of Hematologic Malignancies
- Mim1, The Mcl-1โSpecific Bh3 Mimetic Induces Apoptosis In Human U87Mg Glioblastoma Cells
- Mir-101 And Mcl-1 In Non-Small-Cell Lung Cancer: Expression Profile And Clinical Significance
- Mir-101 Synergistically Enhances Abt-737 Mediated Apoptosis Through Inhibition Of Mcl-1 Expression In Non-Small Cell Lung Cancer
- Mir-106A Targets Mcl-1 To Suppress Cisplatin Resistance Of Ovarian Cancer A2780 Cells
- Mir-137 And Mir-197 Induce Apoptosis And Suppress Tumorigenicity By Targeting Mcl-1 In Multiple Myeloma
- Mir-137 And Mir-197 Within Chromosome 1P Minimal Deletion Region Regulate Apoptotic Activity In Multiple Myeloma By Targeting Mcl 1
- Mirโ139 Inhibits Mclโ1 Expression And Potentiates TmzโInduced Apoptosis In Glioma
- Mir-153 Regulates Apoptosis And Autophagy Of Cardiomyocytes By Targeting Mcl-1
- Mir181 Regulates Mcl-1 Expression In Lyn-Dependent Imatinib-Resistant Cml
- Mirโ181B Increases Drug Sensitivity In Acute Myeloid Leukemia Via Targeting Hmgb1 And Mcl-1
- Mir-193B Modulates Resistance To Doxorubicin In Human Breast Cancer Cells By Downregulating Mcl-1
- Mir-193B Regulates Mcl-1 In Melanoma
- Mir-205 And Mir-218 Expression Is Associated With Carboplatin Chemoresistance And Regulation Of Apoptosis Via Mcl-1 And Survivin In Lung Cancer Cells
- Mir-22 And Mir-29A Are Members Of The Androgen Receptor Cistrome Modulating Lamc1 And Mcl-1 In Prostate Cancer
- Mir-26A Inhibits Proliferation And Migration Of Breast Cancer Through Repression Of Mcl-1
- Mir-29 Regulates Mcl-1 Protein Expression And Apoptosis
- Mir-29A Down-Regulation In Alk-Positive Anaplastic Large Cell Lymphomas Contributes To Apoptosis Blockade Through Mcl-1 Overexpression
- Mir-29A Promotes Intestinal Epithelial Apoptosis In Ulcerative Colitis By Down-Regulating Mcl-1
- Mirโ29B Affects Neurocyte Apoptosis By Targeting Mclโ1 During Cerebral Ischemia/Reperfusion Injury
- Mir-29B And Mir-198 Overexpression In Cd8+ T Cells Of Renal Cell Carcinoma Patients Down-Modulates Jak3 And Mcl-1 Leading To Immune Dysfunction
- Mir-363 Sensitizes Cisplatin-Induced Apoptosis Targeting In Mcl-1 In Breast Cancer
- Mir-519D Impedes Cisplatin-Resistance In Breast Cancer Stem Cells By Down-Regulating The Expression Of Mcl-1
- Mir-9 Enhances The Chemosensitivity Of Aml Cells To Daunorubicin By Targeting The Eif5A2/Mcl-1 Axis
- Mirna-29B Targets Mcl-1 And Is Down-Regulated In Chemotherapy-Resistant Acute Myeloid Leukemia (Aml).
- Mirna98 Induces Apoptosis Of Hcc827 Cell Via Downregulation Of Mcl-1
- Mithramycin A Induces Apoptosis By Regulating The Mtor/Mcl-1/Tbid Pathway In Androgen-Independent Prostate Cancer Cells
- Mitochondria-Independent Cytotoxic Effect Of Nelfinavir On Leukemia Cells Can Be Enhanced By Sorafenib-Mediated Mcl-1 Downregulation And Mitochondrial โฆ
- Mitochondrion-Dependent N-Terminal Processing Of Outer Membrane Mcl-1 Protein Removes An Essential Mule/Lasu1 Protein-Binding Site
- Mitotic Arrest And Jnk-Induced Proteasomal Degradation Of Flip And Mcl-1 Are Key Events In The Sensitization Of Breast Tumor Cells To Trail By โฆ
- Mitotic Arrest-Induced Phosphorylation Of Mcl-1 Revisited Using Two-Dimensional Gel Electrophoresis And Phosphoproteomics: Nine Phosphorylation Sites โฆ
- Ml311: A Small Molecule That Potently And Selectively Disrupts The Protein-Protein Interaction Of Mcl-1 And Bim: A Probe For Studying Lymphoid Tumorigenesis
- Modification Of Alternative Splicing Of Mcl-1 Pre-Mrna Using Antisense Morpholino Oligonucleotides Induces Apoptosis In Basal Cell Carcinoma Cells
- Modification Of Bcl-X And Mcl-1 Pre-Mrna Splicing Using Splice-Switching Oligonucleotides
- Modulation Of Akt, Erk And Mcl-1 By Apigenin Sensitizes Colon Cancer Cells To Anti-Tumor Activities Of Abt263.
- Modulation Of Apoptosis By Berberine Through Inhibition Of Cyclooxygenase-2 And Mcl-1 Expression In Oral Cancer Cells
- Modulation Of Mcl-1 Expression Reduces Age-Related Cochlear Degeneration
- Modulation Of Mcl-1 Sensitizes Glioblastoma To Trail-Induced Apoptosis
- Modulation Of Mcl-1 Transcription By Serum Deprivation Sensitizes Cancer Cells To Cisplatin
- Modulation Of Navitoclax Sensitivity By Dihydroartemisinin-Mediated Mcl-1 Repression In Bcr-Abl+ B-Lineage Acute Lymphoblastic Leukemia
- Modulation Of Noxa And Mcl-1 As A Strategy For Sensitizing Melanoma Cells To The Bh3-Mimetic Abt-737
- Modulator Of Apoptosis (Puma) Chemosensitizes Intrinsically Resistant Ovarian Cancer Cells To Cisplatin By Lowering The Threshold Set By Bcl-X L And Mcl-1
- Molecular Cloning Of Canine Mcl-1 Gene And Its Expression In Tumor Cell Lines
- Molecular Comprehension Of Mcl-1: From Gene Structure To Cancer Therapy
- Molecular Docking Studies Of Anti-Apoptotic Bcl-2, Bcl-Xl, And Mcl-1 Proteins With Ginsenosides From Panax Ginseng
- Molecular Docking Studies Of Bioactive Compounds From Annona Muricata Linn As Potential Inhibitors For Bcl-2, Bcl-W And Mcl-1 Antiapoptotic Proteins
- Molecular Dynamics Study Of Segment Peptides Of Bax, Bim, And Mcl-1 Bh3 Domain Of The Apoptosis-Regulating Proteins Bound To The Anti-Apoptotic Mcl-1 Protein
- Monoclonal Antibody Induces Apoptosis In Chronic Lymphocytic Leukemia B Cells By Downregulating Mcl-1 And Upregulating Bim
- Monosaccharide Digitoxin Derivative Sensitize Human Non-Small Cell Lung Cancer Cells To Anoikis Through Mcl-1 Proteasomal Degradation
- Most Putative Bh3 Mimetics Preferentially Antagonize The Anti-Apoptotic Protein Mcl-1 Rather Than Bcl-2
- Mouse Noxa Uses Only The C-Terminal Bh3-Domain To Inactivate Mcl-1
- Mpt0B169, A Novel Tubulin Inhibitor, Induces Apoptosis In Taxol-Resistant Acute Myeloid Leukemia Cells Through Mitochondrial Dysfunction And Mcl-1 Downregulation
- Mtor Complex 2 (Mtorc2) Positively Regulates Mcl-1 Stability By Suppressing Gsk3-Dependent And Fbxw7-Mediated Proteasomal Degradation Of Mcl-1
- Mtor Complex 2 Stabilizes Mcl-1 Protein By Suppressing Its Glycogen Synthase Kinase 3-Dependent And Scf-Fbxw7-Mediated Degradation
- Mtor Inhibition Specifically Sensitizes Colorectal Cancers With Kras Or Braf Mutations To Bcl-2/Bcl-Xl Inhibition By Suppressing Mcl-1
- Mtorc1 Activity Contributes To The Mcl-1 Dependence Of Her2 Amplified Breast Cancer Cells.
- Mtorc1 Hyperactivity Inhibits Serum Deprivation Apoptosis Via Increased Hkii And Glut1 Expression, Sustained Mcl-1 Expression, And Gsk3ฮ Inhibition
- Mtorc1 Hyperactivity Inhibits Serum Deprivation-Induced Apoptosis Via Increased Hexokinase Ii And Glut1 Expression, Sustained Mcl-1 Expression, And Glycogen โฆ
- Mtorc1 Promotes Survival Through Translational Control Of Mcl-1
- Muc1-C Stabilizes Mcl-1 In The Oxidative Stress Response Of Triple-Negative Breast Cancer Cells To Bcl-2 Inhibitors
- Mule/Arf-Bp1, A Bh3-Only E3 Ubiquitin Ligase, Catalyzes The Polyubiquitination Of Mcl-1 And Regulates Apoptosis
- Mule: Mcl-1 Ubiquitination Ligase E3
- Multiple Mechanisms Of Mcl-1 Depletion By The Cyclin-Dependent Kinase Inhibitor Flavopiridol In Mantle Cell Lymphoma Cell Lines
- Multiple Myeloma Induces Mcl-1 Expression And Survival Of Myeloid-Derived Suppressor Cells
- Multiple Myeloma With 1Q21 Amplification Is Highly Sensitive To Mcl-1 Targeting
- Multiple Myeloma With Amplification Of Chromosome 1Q Is Highly Sensitive To Mcl-1 Targeting
- Multi-Walled Carbon Nanotubes Induce Apoptosis In Normal Human Small Airway Epithelial Cells Through Proteasome-Mediated Mcl-1 Protein Degradation
- Mutant Braf Upregulates Mcl-1 To Confer Apoptosis Resistance That Is Reversed By Mcl-1 Antagonism And Cobimetinib In Colorectal Cancer
- Mutant Braf Upregulates Mcl-1 To Confer Apoptosis Resistance That Is Reversed By Mcl-1 Antagonism And Cobimetinib In Colorectal Cancer.
- Mutant B-Raf-Mcl-1 Survival Signaling Depends On The Stat3 Transcription Factor
- Mutual Activities Of Iex-1 And Mcl-1 On The Apoptosis Of Ovarian Cancer Cells
- Myc Induces Acute Myeloid Leukemia By Conferring Self-Renewal Activity To Committed Myeloid Progenitor Cells That Resist Apoptosis Via Endogenous Mcl-1.
- Myc-Dependent Pi3K And Mcl-1 Feedbacks Attenuate Bet Inhibitors Activity In Diffuse Large B-Cell Lymphoma
- Myeloid Cell Leukemia 1 (Mclโ1) Protects Against 1-Methyl-4-Phenylpyridinium Ion (Mpp+) Induced Apoptosis In Parkinson’S Disease
- Myeloid Cell Leukemia 1 (Mcl-1), An Unexpected Modulator Of Protein Kinase Signaling During Invasion
- Myeloid Cell Leukemia-1 (Mcl-1) Sirna Therapy Showed Cytotoxic Effect On T Cells Acute Lymphoblastic Leukemia
- Myeloid-Specific Deletion Of Mcl-1 Yields Severely Neutropenic Mice That Survive And Breed In Homozygous Form
- Myeloma Exhibits Dependence On Atypical Glucose Transporters: Targeting Mcl-1 Through Glut4 Inhibition
- Nap1L1 Regulates Nf-ฮb Signaling Pathway Acting On Anti-Apoptotic Mcl-1 Gene Expression
- Nbk/Bik Antagonizes Mcl-1 And Bcl-X
- Nbk/Bik Antagonizes Mcl-1 And Bcl-Xl And Activates Bak-Mediated Apoptosis In Response To Protein Synthesis Inhibition
- Ndrg2 Contributes To Cisplatin Sensitivity Through Modulation Of Bak-To-Mcl-1 Ratio
- Nedaplatin Enhanced Apoptotic Effects Of Abt-737 In Human Cancer Cells Via Mcl-1 Inhibition
- Nelfinavir Induces Mitochondria Protection By Erk1/2-Mediated Mcl-1 Stabilization That Can Be Overcome By Sorafenib
- Neuroprotective Effect Of G14-Humanin On Global Cerebral Ischemia/Reperfusion By Activation Of Socs3 โ Stat3 โ Mclโ1 Signal Transduction Pathway In Rats
- Neutralization Of The Transcription Factor Nuclear Factor Erythroid Derived-2 (Nf-E2) Causes Robust Increases In The Anti-Apoptotic Protein Mcl-1 In Human Neutrophils
- New Chemical Tools For Disrupting The Mcl-1/Bh3 Protein-Protein Interaction
- New Face Of Antiapoptotic Proteins. I. Protein Mcl-1
- Nf-ฮb Activation Fails To Protect Cells To Tnfฮฑ-Induced Apoptosis In The Absence Of Bcl-Xl, But Not Mcl-1, Bcl-2 Or Bcl-W
- Nf-ฮb And Mcl-1 Are Important Determinants For The Effectiveness Of Bortezomib In Cd34+ Aml Versus Cd34โ Aml Cells
- Nf-ฮb Is Active In Mcl-1 Promoter Regulation In Human Cll.
- Nfฮบb Signaling And Mcl-1 Are Critical In B Cell Maturation Antigen-Promoted Multiple Myeloma Cell Growth And Survival
- Nicotine Enhances The Antiapoptotic Function Of Mcl-1 Through Phosphorylation
- Nicotine Induces Cell Survival And Chemoresistance By Stimulating Mclโ1 Phosphorylation And Its Interaction With Bak In Lung Cancer
- Nicotine Upregulates The Level Of Mcl-1 Through Stat3 In H1299 Cells
- Nitidine Chloride Represses Mclโ1 Protein Via Lysosomal Degradation In Oral Squamous Cell Carcinoma
- Nkg2D Induces Mcl-1 Expression And Mediates Survival Of Cd8 Memory T Cell Precursors Via Phosphatidylinositol 3-Kinase
- Nkg2D Induces Mcl-1 Expression And Mediates Survival Of Cd8 Memory T Cell Precursors Via Pi3K
- Norcantharidin Enhances Abt-737-Induced Apoptosis In Hepatocellular Carcinoma Cells By Transcriptional Repression Of Mcl-1
- Norcantharidin Induces Mitochondrial-Dependent Apoptosis Through Mcl-1 Inhibition In Human Prostate Cancer Cells
- Notch Signaling Regulates Expression Of Mcl-1 And Apoptosis In Ppd-Treated Macrophages
- Notch Signaling Sustains The Expression Of Mcl-1 And The Activity Of Eif4E To Promote Cell Survival In Cll
- Notch1 Represses Mcl-1 Levels In Gsi-Resistant T-All, Making Them Susceptible To Abt-263
- Notch1 Signaling Promotes Survival Of Glioblastoma Cells Via Egfr-Mediated Induction Of Anti-Apoptotic Mcl-1
- Novel Cyclin Dependent Kinase (Cdk) Inhibitors Induce Down Regulation Of Mcl-1 And Apoptosis In Multiple Myeloma Cells
- Novel Functions Of Mcl-1 In Atm Signalling, Homologous Recombination, And Heterochromatin Dynamics
- Novel Mcl-1 Inhibitor Effectively Restores In Vivo Regorafenib Sensitivity In Resistant Colorectal Cancer
- Novel Mclโ1/Bclโ2 Dual Inhibitors Created By The StructureโBased Hybridization Of DrugโDivided Building Blocks And A Fragment Deconstructed From A Known Two โฆ
- Novel Molecular Therapy Targeting Mcl-1 And Modulating Autophagy In Castration-Resistant Prostate Cancer
- Novel Post-Transcriptional And Post-Translational Regulation Of Pro-Apoptotic Protein Bok And Anti-Apoptotic Protein Mcl-1 Determine The Fate Of Breast Cancer โฆ
- Novel Soluble Myeloid Cell Leukemia Sequence 1 (Mcl-1) Inhibitor (E, E)-2-(Benzylaminocarbonyl)-3-Styrylacrylonitrile (4G) Developed Using A Fragment-Based โฆ
- Novel Tyrosine Kinase Inhibitor Exel-0862 Induces Apoptosis In Human Fip1L1-Pdgfr-ฮ-Expressing Cells Through Caspase-3-Mediated Cleavage Of Mcl-1
- Nox4-Mediated Ros Production Induces Apoptotic Cell Death Via Down-Regulation Of C-Flip And Mcl-1 Expression In Combined Treatment With Thioridazine And โฆ
- Noxa Controls Mule-Dependent Mcl-1 Ubiquitination Through The Regulation Of The Mcl-1/Usp9X Interaction
- Noxa Determines Localization And Stability Of Mcl-1 And Consequently Abt-737 Sensitivity In Small Cell Lung Cancer
- Noxa Induces Apoptosis In Oncogene-Expressing Cells Through Catch-And-Release Mechanism Operating Between Puma And Mcl-1
- Noxa Up-Regulation And Mcl-1 Cleavage Are Associated To Apoptosis Induction By Bortezomib In Multiple Myeloma
- Noxa, A Sensor Of Proteasome Integrity, Is Degraded By 26S Proteasomes By An Ubiquitin-Independent Pathway That Is Blocked By Mcl-1
- Noxa/Mcl-1 Balance Influences The Effect Of The Proteasome Inhibitor Mg-132 In Combination With Anticancer Agents In Pancreatic Cancer Cell Lines
- Noxa/Mcl-1 Balance Regulates Susceptibility Of Cells To Camptothecin-Induced Apoptosis
- Npm-Alk Regulated Gsk3ฮ Phosphorylation Results In Mcl-1 And Cdc25A Accumulation And Enhanced Oncogenic Potential
- Nuclear Topography Of The 1Q21 Genomic Region And Mcl-1 Protein Levels Associated With Pathophysiology Of Multiple Myeloma
- Nucleoside Analog Arc Targets Mcl-1 To Induce Apoptosis In Leukemia Cells
- Nvp-Bez235-Induced Apoptosis In Human Renal Carcinoma Caki Cells Through Down-Regulation Of P53-Dependent Bcl-2 Expression And Inhibition Of Mcl-1 โฆ
- Obatoclax (Gx15-070) Is A Potent Antagonist Of Constitutive Mcl-1/Bak Interactions In Intact Mitochondrial Membrane And Synergizes With Bortezomib In Mantle Cell โฆ
- Obatoclax Is A Direct And Potent Antagonist Of Membrane-Restricted Mcl-1 And Is Synthetic Lethal With Treatment That Induces Bim
- Obesity And Il-6 Promote Liver Carcinogenesis Via Mcl-1 Stabilization
- Obesity Promotes Liver Carcinogenesis Via Mcl-1 Stabilization Independent Of Il-6Rฮฑ Signaling
- Obligate Role Of Anti-Apoptotic Mcl-1 In The Survival Of Hematopoietic Stem Cells
- Observation On The Antisense Mcl-1 Transfected Malignant Melanoma Cells By Light Microscope And Electron Microscope
- Occurs By A Mechanism Involving The Activation Of Pro-Apoptotic Bcl-2 Proteins Bak And Bid And The Inactivation Of Anti-Apoptotic Bcl-2 Proteins Bcl-Xl And Mcl-1
- Of Adult Rat Germ Cell Death After Exposure To Xenoestrogens: Role Of Microrna Mir-29 Family In The Down-Regulation Of Dna Methyltransferases And Mcl-1
- Of Cd44, A Receptor For Extracellular Matrix Components, Protects Chronic Lymphocytic Leukemia Cells From Spontaneous And Drug Induced Apoptosis Through Mcl-1
- Of Docetaxel-Induced Cytotoxicity And Apoptosis By All-Trans Retinoic Acid (Atra) Through Downregulation Of Survivin (Birc5), Mcl-1 And Ltbeta-R In โฆ
- Of Marinopyrrole A (Maritoclax) As A Selective Mcl-1 Antagonist That Overcomes Abt-737 Resistance By Binding To And Targeting Mcl-1 For Proteasomal Degradation
- Of Mcl-1 As A Novel Target In Neoplastic Mast Cells And Demonstration Of Cooperative Growth-Inhibitory Effects Of Mcl-1 Antisense Oligonucleotides, Pkc412, And โฆ
- Of Nf-ฮb-Regulated Balance Of Anti-Apoptotic And Pro-Apoptotic Activity By Controlling Transcription And Cleavage Of Mcl-1
- Of The Bcl-2 Inhibitor Abt199 (Venetoclax) In Bcl-2 High-Expressing Neuroblastoma Cell Lines And Xenografts And Rational For Combination With Mcl-1 โฆ
- Of The Human Mcl-1 Gene Encoding An Anti-Apoptotic Member Of The Bcl-2 Family: The Role Of Sp1 And Of Basic Transcription Factor Binding Sites In The Mcl-1 โฆ
- Of The Mtorc1/Torc2 Inhibitor Ink128 And The Bcl-2/Bcl-Xl Antagonist Abt-737 Kills Human Myeloid Leukemia Cells Through Mcl-1 Down-Regulation And Akt โฆ
- Of Xpo1 By Kpt-330 (Selinexor) Enhances Cell Death Induced By The Bcl-2 Selective Inhibitor Abt-199 (Venetoclax) Through Downregulation Of Mcl-1 In Acute Myeloid โฆ
- Omacetaxine May Have A Role In Chronic Myeloid Leukaemia Eradication Through Downregulation Of Mcl-1 And Induction Of Apoptosis In Stem/Progenitor Cells
- Oncostatin M-Dependent Mcl-1 Induction Mediated By Jak1/2-Stat1/3 And Creb Contributes To Bioenergetic Improvements And Protective Effects Against โฆ
- Opposing Mcl-1, The Galig Proapoptotic Gene Is Upregulated As Neutrophils Die And Underexpressed In Acute Myeloid Leukemia Cells
- Optimal Targeting Of Bcl-Family Proteins In Head And Neck Squamous Cell Carcinoma Requires Inhibition Of Both Bcl-Xl And Mcl-1
- Or In A Supportive Microenvironment And Is Synergistic With Fludarabine In A Mechanism That Involves Decreased Levels Of Reactive Oxygen Species And Mcl-1 โฆ
- Ouabain Downregulates Mcl-1 And Sensitizes Lung Cancer Cells To Trail-Induced Apoptosis
- Ovarian Cancer Ascites Increase Mcl-1 Expression In Tumor Cells Through Erk1/2-Elk-1 Signaling To Attenuate Trail-Induced Apoptosis
- Overcomes Resistance Of Hepatocellular Carcinomas Against Chemotherapy And Tumor Necrosis FactorโRelated Apoptosis-Inducing Ligand By Elimination Of Mcl-1
- Overcoming Acquired Resistance To Azd9291, A Third-Generation Egfr Inhibitor, Through Modulation Of Mek/Erk-Dependent Bim And Mcl-1 Degradation
- Overcoming Chemoresistance In Pancreatic Cancer By Targeting The Anti-Apoptotic Mcl-1 Protein
- Overexpression Of AntiโApoptotic Mclโ1 In Testicular Germ Cell Tumours
- Overexpression Of Mcl-1 Attenuates Liver Injury And Fibrosis In The Bile DuctโLigated Mouse
- Overexpression Of Mcl-1 Confers Multidrug Resistance, Whereas Topoisomerase Iiฮฒ Downregulation Introduces Mitoxantrone-Specific Drug Resistance In Acute Myeloid โฆ
- Overexpression Of Mcl-1 Confers Resistance To Brafv600E Inhibitors Alone And In Combination With Mek1/2 Inhibitors In Melanoma
- Overexpression Of Mcl-1 Exacerbates Lymphocyte Accumulation And Autoimmune Kidney Disease In Lpr Mice
- Over-Expression Of Mcl-1 Impairs The Ability Of Atra To Induce Growth Arrest And Differentiation In Acute Promyelocytic Leukemia Cells
- Overexpression Of Mcl-1 In Anaplastic Large Cell Lymphoma Cell Lines And Tumors
- Overexpression Of Microrna-29B Induces Apoptosis Of Multiple Myeloma Cells Through Down Regulating Mcl-1
- Overexpression Of Mir-101 Promotes Trail-Induced Mitochondrial Apoptosis In Papillary Thyroid Carcinoma By Targeting C-Met And Mcl-1
- Overexpression Of P-Stat3 And Mcl-1, And Their Correlation With Differentiation And Apoptotic Resistance In Esophageal Squamous Cell Carcinoma
- Overexpression Of The Anti-Apoptotic Genes Mcl-1, Bcl-W, Bcl-Xl And A1 Is Correlated With Chronic Myelogenous Leukemia Progression And Resistance To Gleevec.
- P32, A Novel Binding Partner Of Mcl-1, Positively Regulates Mitochondrial Ca2+ Uptake And Apoptosis
- P38 Mapk Controls Sensitivity Towards Bh3 Mimetics By Regulating Mcl-1 Expression Of Chronic Lymphocytic Leukemia In Hypoxia And Acquired Resistance
- P53-Dependent Regulation Of Mcl-1 Contributes To Synergistic Cell Death By Ionizing Radiation And The Bcl-2/Bcl-Xl Inhibitor Abt-737
- Paclitaxel In Combination With At-101 Induces Apoptosis Via Supressing Bcl-2, Bcl-Xl, Mcl-1 Proteins In Human Breast Cancer Cells.
- Pan-Mammalian Target Of Rapamycin (Mtor) Inhibitor Azd8055 Primes Rhabdomyosarcoma Cells For Abt-737-Induced Apoptosis By Down-Regulating Mcl-1 Protein
- Parkin Sensitizes Toward Apoptosis Induced By Mitochondrial Depolarization Through Promoting Degradation Of Mcl-1
- Parkin-Dependent Degradation Of The F-Box Protein Fbw7ฮ Promotes Neuronal Survival In Response To Oxidative Stress By Stabilizing Mcl-1
- Pathways In Cutaneous Squamous Cell Carcinoma Cells By Diclofenac/Hyaluronic Acid Is Related To Upregulation Of Bad As Well As Downregulation Of Mclโ1 And BclโW
- Paxillin Confers Resistance To Tyrosine Kinase Inhibitors In Egfr-Mutant Lung Cancers Via Modulating Bim And Mcl-1 Protein Stability
- Pcna And Anti-Apoptotic Mcl-1 Proteins Predict Disease-Free Survival In Oral Cancer Patients Treated With Definitive Radiotherapy
- Pdgf Regulation Of Mcl-1 Expression In Bone-Metastatic Human Prostate Cancer Cells
- Pdgf Upregulates Mcl-1 Through Activation Of ฮ-Catenin And Hif-1ฮ-Dependent Signaling In Human Prostate Cancer Cells
- Pemetrexed Exerts Anticancer Effects By Inducing G0/G1โPhase Cell Cycle Arrest And Activating The Noxa/Mclโ1 Axis In Human Esophageal Squamous Cell โฆ
- Persistent Hepatitis C Virus (Hcv) Infection Impairs HcvโSpecific Cytotoxic T Cell Reactivity Through Mclโ1/Bim Imbalance Due To Cd127 DownโRegulation
- Persistent Mcl-1/Bim Protein Signature After Cd40 Ligation In Chronic Lymphocytic Leukemia Is Associated With Specific Drug Sensitivity
- Phenylethyl Isothiocyanate Reverses Cisplatin Resistance In Biliary Tract Cancer Cells Via Glutathionylation-Dependent Degradation Of Mcl-1
- Phosphatidylinositol 3-Kinase And P38 Mitogen-Activated Protein Kinase Regulate Induction Of Mcl-1 And Survival In Glucocorticoid-Treated Human Neutrophils
- Phosphorylated Bcl-2 And Mcl-1 As Prognostic Markers In Small Cell Lung Cancer
- Phosphorylation Alters BimโMediated Mclโ1 Stabilization And Priming
- Phosphorylation Of Mclโ1 By Cdk1โCyclin B1 Initiates Its Cdc20โDependent Destruction During Mitotic Arrest
- Photocatalytic Proximity Labelling Of Mcl-1 By A Bh3 Ligand
- Phytosterols And Triterpenes From Morinda Lucida Benth (Rubiaceae) As Potential Inhibitors Of Anti-Apoptotic Bcl-Xl, Bcl-2, And Mcl-1: An In-Silico Study
- Pi3K And Bcl-2 Inhibition Primes Glioblastoma Cells To Apoptosis Through Downregulation Of Mcl-1 And Phospho-Bad
- Pi3K And P38 Mapk Regulate Induction Of Mcl-1 And Survival In Glucocorticoid Treated Human Neutrophils
- Pi3K/Mtor Dual Inhibitor Nvp-Bez235 Decreases Mcl-1 Expression And Sensitizes Ovarian Carcinoma Cells To Bcl-Xl-Targeting Strategies, Provided That Bim โฆ
- Pi3K/Mtor Inhibition Markedly Potentiates Hdac Inhibitor Activity In Nhl Cells Through Bim-And Mcl-1โDependent Mechanisms In Vitro And In Vivo
- Pi3K-Dependent Upregulation Of Mcl-1 By Human Cytomegalovirus Is Mediated By Epidermal Growth Factor Receptor And Inhibits Apoptosis In Short-Lived Monocytes
- Pik3Ca Mutations Enable Targeting Of A Breast Tumor Dependency Through Mtor-Mediated Mcl-1 Translation
- Pk11195, A Mitochondrial Benzodiazepine Receptor Antagonist, Reduces Apoptosis Threshold In Bcl-Xl And Mcl-1 Expressing Human Cholangiocarcinoma Cells
- Plasticity Of Bh3 Domain-Binding Hydrophobic Grooves In The Anti-Apoptotic Mcl-1 And A1 Proteins
- Platinum Compounds Sensitize Ovarian Carcinoma Cells To Abt-737 By Modulation Of The Mcl-1/Noxa Axis
- Platinum Sensitize Ovarian Carcinoma Cells To Abt-737 In Vitro And Ex Vivo Through Inhibition Of Mcl-1
- Po-061 Bcl-2 Family Of Proteins, Bcl-Xl And Mcl-1, Regulate Apoptosis And Cancer Cell Survival By Different Mechanisms
- Polymeric Delivery Of Sirna For Dual Silencing Of Mcl-1 And P-Glycoprotein And Apoptosis Induction In Drug-Resistant Breast Cancer Cells
- Polymeric Micelles For Mcl-1 Gene Silencing In Breast Tumors Following Systemic Administration
- Polymorphisms In The Promoter Region Of The Mcl-1 Gene Are Associated With Ex Vivo Cytotoxicity But Not With Response To Treatment In Advanced Chronic โฆ
- Potent And Selective Small-Molecule Mcl-1 Inhibitors Demonstrate On-Target Cancer Cell Killing Activity As Single Agents And In Combination With Abt-263 โฆ
- Potent Efficacy Of Mcl-1 Inhibitor-Based Therapies In Preclinical Models Of Mantle Cell Lymphoma
- Potential Pharmacological Chaperones Targeting Cancer-Associated Mcl-1 And Parkinson Disease-Associated ฮ-Synuclein
- Potently Increases The Sensitivity Of Resistant Acute Myeloid Leukemia Lines To The Bcl-2 Inhibitor Venetoclax By Mediating A Reduction In Cellular Mcl-1 Levels
- Pparฮณ Is Critical For Mycobacterium Tuberculosis Induction Of Mcl-1 And Limitation Of Human Macrophage Apoptosis
- Pre Clinical Mtor-Inhibition Of Acute Lymphoblastic Leukemia Cells Synergizes With Pro-Apoptotic Target Therapy Through Mcl-1 Down-Regulation
- Pre-Apoptotic Response To Therapeutic Dna Damage Involves Protein Modulation Of Mcl-1, Hdm2 And Flt3 In Acute Myeloid Leukemia Cells
- Pre-Clinical Assessment Of Mcl-1 As A Therapeutic Target In T-Cell Lymphomas
- Preclinical Efficacy Of Sepantronium Bromide (Ym155) In Multiple Myeloma Is Conferred By Down Regulation Of Mcl-1
- Preclinical Evaluation Of Amg 176, A Novel, Potent And Selective Mcl-1 Inhibitor With Robust Anti-Tumor Activity In Mcl-1 Dependent Cancer Models
- Pre-Clinical Evaluation Of Mcl-1 Inhibition Through Maritoclax In Acute Myeloid Leukemia
- Preclinical Evaluation Of The Simultaneous Inhibition Of Mcl-1 And Bcl-2 With The Combination Of S63845 And Venetoclax In Multiple Myeloma.
- Preclinical Studies Of Apogossypolone, A Novel Pan Inhibitor Of Bcl-2 And Mcl-1, Synergistically Potentiates Cytotoxic Effect Of Gemcitabine In Pancreatic Cancer โฆ
- Preclinical Studies Of Apogossypolone: A New Nonpeptidic Pan Small-Molecule Inhibitor Of Bcl-2, Bcl-Xl And Mcl-1 Proteins In Follicular Small Cleaved Cell โฆ
- Predicting Cellular Response To Small Molecule Mcl-1 Antagonists
- Predicting Response To Mcl-1 Targeting Agents In Nsclc And Multiple Myeloma
- Preferential Targeting Of Mcl-1 By A Hydrocarbon-Stapled Bim Bh3 Peptide
- Preparation Of Prokaryotic Expression Construct Of Bufo Japonicus Formosus Mcl-1 And Its Recombinant Protein Expression
- Prevention Of Cytokine Withdrawal-Induced Apoptosis By Mcl-1 Requires Interaction Between Mcl-1 And Bim
- Prevents Mcl-1 Protein Dephosphorylation At The Thr-163/Ser-159 Phosphodegron, Dramatically Reducing Expression In Mcl-1-Amplified Lymphoma Cells
- Proapoptotic Bak Is Sequestered By Mcl-1 And Bcl-Xl, But Not Bcl-2, Until Displaced By Bh3-Only Proteins
- Pro-Apoptotic Meiogynin A Derivatives That Target Bcl-Xl And Mcl-1
- Probing The Difference Between Bh3 Groove Of Mcl-1 And Bcl-2 Protein: Implications For Dual Inhibitors Design
- Prognostic Role Of Myeloid Cell Leukemiaโ1 Protein (Mclโ1) Expression In Human Gastric Cancer
- Prognostic Significance Of A Short Sequence Insertion In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia
- Progress In Research Of Structure, Function And Inhibitors Of Mcl-1 Protein
- Progress Of Study On Relationship Between Mcl-1 Gene And Hematologic Malignancies-Review
- Progress On Mcl-1 Small Molecule Inhibitors
- Progression Of Rsearch For On Mcl-1 Mlecule [J]
- Proinflammatory Lipids In Stored Blood And From Injury Delay Neutrophil Apoptosis Via Mcl-1 Expression.: 72
- Prolactin Regulation Of Bcl-2 Family Members: Increased Expression Of Bcl-Xl But Not Mcl-1 Or Bad In Nb2-T Cells
- Prolyl Hydroxylase 3 Attenuates Mcl-1โMediated Atp Production To Suppress The Metastatic Potential Of Colorectal Cancer Cells
- Promiscuous And Selective: How Intrinsically Disordered Bh3 Proteins Interact With Their Pro-Survival Partner Mcl-1
- Promoter Knock-In Mutations Reveal A Role Of Mcl-1 In Thymocyte-Positive Selection And Tissue Or Cell Lineage-Specific Regulation Of Mcl-1 Expression
- Promoting Vaginal Distribution Of E7 And Mcl-1 Sirna-Silencing Nanoparticles For Cervical Cancer Treatment
- Prospects For Drug Designing: Similar Conserved Interactions Of Bim With Mcl-1 And Bcl-2
- Proteasomal Degradation Of Mcl-1 By Maritoclax Induces Apoptosis And Enhances The Efficacy Of Abt-737 In Melanoma Cells
- Proteasome Inhibitors Induce Apoptosis In Human Lung Cancer Cells Through A Positive Feedback Mechanism And The Subsequent Mcl-1 Protein Cleavage
- Protection From Cell Death By Mcl-1 Is Mediated By Membrane Hyperpolarization Induced By K+ Channel Activation
- Protection Of Cll B Cells By A Follicular Dendritic Cell Line Is Dependent On Induction Of Mcl-1
- Protective Effect Of Melatonin On OxaliplatinโInduced Apoptosis Through Sustained Mclโ1 Expression And AntiโOxidant Action In Renal Carcinoma Caki Cells
- Protein Kinase C-Eta Regulates Mcl-1 Level Via Erk1
- Protein Kinase Ck2 Enhances Mclโ1 Gene Expression Through The Serum Response FactorโMediated Pathway In The Rat Hippocampus
- Protein Kinase G TypeโIฮฑ (PkgโIฮฑ) Signaling Pathway Promotes Creb Phosphorylation And Maintains Higher CโIap1, Livin, Survivin, And Mclโ1 Expression And The โฆ
- Protein Phosphatase 1 Activation And Alternative Splicing Of BclโX And Mclโ1 By Egcg+ Ibuprofen
- Proteolysis Targeting Chimeras For The Selective Degradation Of Mcl-1/Bcl-2 Derived From Nonselective Target Binding Ligands
- Ps06. 02 Drug-Tolerant Egfr Mutant Lung Cancer Cells Rely On Mcl-1 Translation And Are Eliminated By Mcl-1 Inhibitors: Topic: Pulmonology
- Pseudomonas Exotoxin A-Mediated Apoptosis Is Bak Dependent And Preceded By The Degradation Of Mcl-1
- Puma* Mcl-1 Interaction Is Not Sufficient To Prevent Rapid Degradation Of Mcl-1
- Purified Mouse Anti-Human Mcl-1
- Purported Mcl-1 Inhibitor Marinopyrrole A Fails To Show Selective Cytotoxicity For Mcl-1-Dependent Cell Lines
- Pyoluteorin Derivatives Induce Mcl-1 Degradation And Apoptosis In Hematological Cancer Cells
- Pyridoclax And Its Derivatives From Oligopyridine Family Directly Inhibit Mcl-1 And Exert Potent Antitumor Effects On Ovarian Cancer In Vitro And In Vivo
- Quercetin Downregulates Mcl-1 By Acting On Mrna Stability And Protein Degradation
- Quercetin Induces Tumor-Selective Apoptosis Involving Downregulation Of Mcl-1 And Activation Of Bax
- Quercetin Induces Tumor-Selective Apoptosis Through Downregulation Of Mcl-1 And Activation Of Bax
- Quercetin-Mediated Mcl-1 And Survivin Downregulation Restores Trail-Induced Apoptosis In Non-Hodgkin Lymphoma B-Cells
- Quercetin-Mediated Mcl-1 And Survivin Downregulation Restores Trail-Induced Apoptosis In Non-Hodgkin’S Lymphoma B Cells
- Quinacrine Sensitizes Hepatocellular Carcinoma Cells To Trail Via Up-Regulating Dr5 And Eradicating Mcl-1
- Rankl Increases The Level Of Mcl-1 In Osteoclasts And Reduces Bisphosphonate-Induced Osteoclast Apoptosis In Vitro
- Rapid Optimization Of Mcl-1 Inhibitors Using Stapled Peptide Libraries Including Non-Natural Side Chains
- Rapid Turnover Of Mcl-1 Couples Translation To Cell Survival And Apoptosis
- Rassf6-Mediated Inhibition Of Mcl-1 Through Jnk Activation Improves The Anti-Tumor Effects Of Sorafenib In Renal Cell Carcinoma
- Rational Design Of Proteolytically Stable, Cell-Permeable Peptide-Based Selective Mcl-1 Inhibitors
- Rational For A Combination Of Bortezomib And Doxorubicin In The Treatment Of Multiple Myeloma: A Pivotal Role For Mcl-1.
- Rationally Derived Drug Combinations With The Novel Mcl-1 Inhibitor Eu-5346 In Breast Cancer
- Rb, Mcl-1 And P53 Expression Correlate With Clinical Outcome In Patients With Liver Metastases From Colorectal Cancer
- Re: Prognostic Significance Of A Short Sequence Insertion In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia
- Reactive Oxygen Species Mediate Cancer Stem-Like Cells And Determine Bortezomib Sensitivity Via Mcl-1 And Zeb-1 In Mantle Cell Lymphoma
- Recent Advances In Cancer Drug Development: Targeting Induced Myeloid Cell Leukemia-1 (Mcl-1) Differentiation Protein
- Recent Advances In The Development Of Mcl-1 Inhibitors For Cancer Therapy
- Reciprocal Protection Of Mcl-1 And Bim From Ubiquitin-Proteasome Degradation
- Recombinant Mda-7/Il24 Suppresses Prostate Cancer Bone Metastasis Through Downregulation Of The Akt/Mcl-1 Pathway
- Reduced Association Of Anti-Apoptotic Protein Mcl-1 With E3 Ligase Mule Increases The Stability Of Mcl-1 In Breast Cancer Cells
- Reduced Mast Cell And Basophil Numbers And Function In Cpa3-Cre; Mcl-1Fl/Fl Mice
- Reducing Mcl-1 By Homoharringtonine Induces Apoptosis In Chronic Lymphocytic Leukemia Cells
- Reducing Mcl-1 Gene Dosage Induces Dopaminergic Neuronal Loss And Motor Impairments In Park2 Knockout Mice
- Reduction Of Trail-Induced Mcl-1 And Ciap2 By C-Myc Or Sorafenib Sensitizes Resistant Human Cancer Cells To Trail-Induced Death
- Regulated Expression Of Anti-Apoptotic Mcl-1 And A1 Controls The Population Structure Of Myeloid Derived Suppressor Cells (P1070)
- Regulation Of 2-Methoxyestradiol-Induced Cell Apoptosis By Mcl-1 And Bax Genes In Myelodysplastic Syndrome
- Regulation Of A1 And Mcl-1 From Costimulatory Signals Affects T Cell Survival (47.2)
- Regulation Of Anti-Apoptotic Bcl-2 Family Protein Mcl-1 By S6 Kinase 2
- Regulation Of Antiapoptotic Mcl-1 Function By Gossypol: Mechanistic Insights From In Vitro Reconstituted Systems
- Regulation Of Heat-Induced Apoptosis By Mcl-1 Degradation And Its Inhibition By Hsp70
- Regulation Of Intestinal Epithelial Apoptosis By Protease-Activated Receptor 2 Involves Egfr-Transactivation And Is Associated With Mcl-1 Upregualtion (151.1)
- Regulation Of Macrophage Cell Death Proteins Mcl-1 And Bax During Infection By Mycobacterium Tuberculosis
- Regulation Of Mcl-1 Alternative Splicing By Hnrnp F, H1 And K In Breast Cancer Cells
- Regulation Of Mcl-1 And Caspase Family Members In Pmn By Laminin And Oxidative Stress.: 222
- Regulation Of Mcl-1 By Constitutive Activation Of Nf-Kappab Contributes To Cell Viability In Human Esophageal Squamous Cell Carcinoma Cells
- Regulation Of Mcl-1 By E2F-1 In Endoplasmic Reticulum Stress In Gastric Adenocarcinoma Cells [J]
- Regulation Of Mcl-1 By Srsf1 And Srsf5 In Cancer Cells
- Regulation Of Mcl-1 Expression In Context To Bone Marrow Stromal Microenvironment In Chronic Lymphocytic Leukemia
- Regulation Of Mclโ1 Expression In Rheumatoid Arthritis Synovial Macrophages
- Regulation Of Neutrophil Apoptosis By Mcl-1
- Regulation Of Neutrophil Survival/Apoptosis By Mcl-1
- Regulation Of Placental Autophagy By The Bcl-2 Family Proteins Myeloid Cell Leukemia Factor 1 (Mcl-1) And Matador/Bcl-2 Related Ovarian Killer (Mtd/Bok)
- Regulation Of The Bcl-2 Family Members Bim, Puma And Mcl-1 By Mek/Erk Signaling Plays A Critical Role In Survival Of Melanoma Cells
- Relationship Of Mcl-1 Isoforms, Ratio P21Waf1/Cyclin A, And Jun Kinase Phosphorylation To Apoptosis In Human Breast Carcinomas
- Renieramycin T Induces Lung Cancer Cell Apoptosis By Targeting Mcl-1 Degradation: A New Insight In The Mechanism Of Action
- Reply To Hu Et Al.: Mcl-1 Reduction Due To Caspase-Dependent Cleavage During Endoplasmic Reticulum Stress-Induced Apoptosis
- Repression Of Mcl-1 And Disruption Of The Mcl-1/Bak Interaction In Myeloma Cells Couple Er Stress To Mitochondrial Apoptosis
- Repression Of Mcl-1 Expression By The Cdc7/Cdk9 Inhibitor Pha-767491 Overcomes Bone Marrow Stroma-Mediated Drug Resistance In Aml
- Repurposing Of Mtor Complex Inhibitors Attenuates Mcl-1 And Sensitizes To Parp Inhibition
- Requirement For Antiapoptotic Mcl-1 In The Survival Of Bcr-Abl B-Lineage Acute Lymphoblastic Leukemia
- Resistance To The Novel Translation Inhibitor Silvestrol Is Mediated By Elevated Mcl-1 Expression.
- Response To Yang-Yen: Does N-Terminal Processing Of Mcl-1 Occur At Mitochondrial Outer Membrane Or Matrix?
- Response: Re: Prognostic Significance Of A Short Sequence Insertion In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia
- Resveratrol And Clofarabine Induces A Preferential Apoptosis-Activating Effect On Malignant Mesothelioma Cells By Mcl-1 Down-Regulation And Caspase-3 โฆ
- Resveratrol Suppresses Cell Proliferation Via Inhibition Of Stat3 Phosphorylation And Mcl-1 And Ciap-2 Expression In Htlv-1-Infected T Cells
- Revealing A Non-Canonical Role Of Anti-Apoptotic Mcl-1 In Early Embryonic Development
- Rna Antagonist Compounds For The Modulation Of Mcl-1
- Rna Silencing Of Mcl-1 Enhances Abt-737-Mediated Apoptosis In Melanoma: Role For A Caspase-8-Dependent Pathway
- Rnai-Mediated Inhibition Of Mcl-1 Expression Enhances Apoptosis In Imatinib-Treated Cml Progenitors
- Role Of Bile Salt In Regulating Mcl-1 Phosphorylation And Chemoresistance In Hepatocellular Carcinoma Cells
- Role Of Ku70 In Deubiquitination Of Mcl-1 And Suppression Of Apoptosis
- Role Of Mcl-1 In Regulation Of Cell Death In Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes In Vitro
- Role Of MitogenโActivated Protein Kinases And Mclโ1 In Apoptosis Induction By Withaferin A In Human Breast Cancer Cells
- Role Of Myeloid Cell Factor-1 (Mcl-1) In Chronic Lymphocytic Leukemia
- Role Of Myeloid Cell Leukemia 1 (Mcl-1) In Mediating Chemoresistance Towards Bcl-2 Homology 3 (Bh3) Mimetics In Lymphoid Malignancies
- Role Of Non-Native Electrostatic Interactions In The Coupled Folding And Binding Of Puma With Mcl-1
- Role Of Raf/Mek/Erk Pathway, PโStatโ3 And Mclโ1 In Sorafenib Activity In Human Pancreatic Cancer Cell Lines
- Roles Of Microrna-29A In Expression Of Bcl-2 And Mcl-1 In Rat Cardiomyocytes
- Roscovitine-Induced Apoptosis In Neutrophils And Neutrophil Progenitors Is Regulated By The Bcl-2-Family Members Bim, Puma, Noxa And Mcl-1
- Running Title: Mcl-1 And Mitochondrial Ca2
- S1, A Bid-Like Bh3 Mimetic, Induces Apoptosis By Dynamic Change Of Mcl-1 And Dependent On Bak, Not Bax
- S1, A Novel Pan-Bh3 Mimetic, Induces Apoptosis In Mcl-1-Overexpressing Cells Through Bak
- S63845, A Novel Bh3 Mimetic Mcl-1 Inhibitor Synergizes With Midostaurin To Induce Potent Apoptosis In Acute Myeloid Leukemia Cells Carrying Flt3-Itd Mutations
- S63845, An Mcl-1 Selective Bh3 Mimetic: Another Arrow In Our Quiver
- S6K1 Inhibition Enhances Tamoxifen-Induced Cell Death In Mcf-7 Cells Through Translational Inhibition Of Mcl-1 And Survivin
- Sabutoclax (Bi97C1) And Bi112D1, Putative Inhibitors Of Mcl-1, Induce Mitochondrial Fragmentation Either Upstream Of Or Independent Of Apoptosis
- Sabutoclax, A Mcl-1 Antagonist, Inhibits Tumorigenesis In Transgenic Mouse And Human Xenograft Models Of Prostate Cancer
- Saga Of Mcl-1: Regulation From Transcription To Degradation
- Sann-Joong-Kuey-Jian-Tang Decreases The Protein Expression Of Mclโ1 And Tctp And Increases That Of Tnf-ฮ And Bax In Bxpcโ3 Pancreatic Carcinoma Cells
- Sar By Interligand Nuclear Overhauser Effects (Iloes) Based Discovery Of Acylsulfonamide Compounds Active Against Bcl-Xl And Mcl-1
- Sec6/8 Regulates Bcl-2 And Mcl-1, But Not Bcl-Xl, In Malignant Peripheral Nerve Sheath Tumor Cells
- SecuridacaโSaponins Are Natural Inhibitors Of Akt, Mcl-1, And Bcl2L1 In Cervical Cancer Cells
- SecuridacaโSaponins Are Natural Inhibitors Of Akt, Mcl-1, And Bcl2L1 In Cervical Cancer Cells [Corrigendum]
- ‘Seed’Analysis Of Off-Target Sirnas Reveals An Essential Role Of Mcl-1 In Resistance To The Small-Molecule Bcl-2/Bcl-X L Inhibitor Abt-737
- Seeking A Mcl-1 Inhibitor
- Selection Of Antibodies For Immunohistochemical Detection Of Bcl-2 Family Members In Dogs And Immunohistochemical Expression Pattern Of Mcl-1 And Bcl-X In Canine โฆ
- Selective Bh3-Mimetics Targeting Bcl-2, Bcl-Xl Or Mcl-1 Induce Severe Mitochondrial Perturbations
- Selective Cdk9 Inhibition Overcomes Trail Resistance By Concomitant Suppression Of Cflip And Mcl-1
- Selective Flt3 Inhibitor Fi-700 Neutralizes Mcl-1 And Enhances P53-Mediated Apoptosis In Aml Cells With Activating Mutations Of Flt3 Through Mcl-1/Noxa โฆ
- Selective Induction Of Cell Death In Melanoma Cell Lines Through Targeting Of Mcl-1 And A1
- Selective Inhibitors Of Mcl-1 With Potent Activity Against Multiple Myeloma Patient Cells And Animal Xenografts.
- Selective Mcl-1 Inhibition By Azd5991 Induces On-Target Cell Death And Achieves Antitumor Activity In Multiple Myeloma And Acute Myeloid Leukemia
- Selective Roles For Antiapoptotic Mcl-1 During Granulocyte Development And Macrophage Effector Function
- Selective Small Molecule Inhibition Of Anti-Apoptotic Mcl-1
- Selective Small Molecule Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors: Novel Agents In Cancer Therapy
- Selective Small Molecule Targeting Of Anti-Apoptotic Mcl-1
- Selectively Targeting Mcl-1 For The Treatment Of Acute Myelogenous Leukemia And Solid Tumors
- Seliciclib (Cyc202 Or R-Roscovitine), A Small-Molecule Cyclin-Dependent Kinase Inhibitor, Mediates Activity Via Down-Regulation Of Mcl-1 In Multiple Myeloma
- Sensitization Of Colon Cancer (Cc) Cells To The Cytotoxic Ligand Trail By The Cox-2 Inhibitor Dup-697 Correlates With Downregulation Of Mcl-1 And Clustering Of Dr5
- Sensitization Of Ovarian Carcinoma Cells To Bcl-Xl-Targeting Strategies Through Indirect Modulation Of Mcl-1 Activity By Mr22388, A Molecule Of The Tripentone โฆ
- Serine 162, An Essential Residue For The Mitochondrial Localization, Stability And Anti-Apoptotic Function Of Mcl-1
- Serine 64 Phosphorylation Enhances The Antiapoptotic Function Of Mcl-1
- Serine Phosphorylation Of Stat3 Is Essential For Mcl-1 Expression And Macrophage Survival
- Sf3B1 Inhibitors Sensitize Head And Neck Squamous Cell Carcinoma To Bcl-Xl Inhibition By Regulating Mcl-1 Alternative Splicing.
- Shiga Toxin Induces Decreased Expression Of The Anti-Apoptotic Protein Mcl-1 Concomitant With The Onset Of Endothelial Apoptosis
- Short Nucleotide Insertions In The Mcl-1 Promoter Affect Its Gene Expression.
- Short Nucleotide Polymorphic Insertions In The Mcl-1 Promoter Affect Gene Expression
- Side-By-Side Comparison Of Bh3-Mimetics Identifies Mcl-1 As A Key Therapeutic Target In Aml
- Significance Of Mcl-1 Expressions In Gastric Cancer By Tissue Microarray
- Silence Of Mcl-1 Upstream Signaling By Shrna Abrogates Multiple Myeloma Growth
- Silencing Of Mcl-1 By Mir-101 Induces Apoptosis And Enhances Etoposide Chemosensitivity In A549 Lung Cancer Cells
- Simultaneous Chk1 And Mek1/2 Inhibition Circumvents Mcl-1 Anti-Apoptotic Function And Bortezomib Resistance In Human Multiple Myeloma Cells
- Simultaneous Chk1 And Mek1/2 Inhibition Circumvents Mcl-1-Mediated Anti-Apoptotic Functions And Bortezomib Resistance In Human Multiple Myeloma Cells.
- Simultaneous Inhibition Of Dna Methyltransferase And Histone Deacetylase Induces P53-Independent Apoptosis Via Down-Regulation Of Mcl-1 In Acute Myelogenous โฆ
- Simultaneous Inhibition Of Mcl-1 And Induction Of Dna Damage Accumulation By Chidamide, A Novel Selective Hdaci, Potentiates The Cytotoxicity Of Abt-199 In โฆ
- Simultaneous Inhibition Of Mcl-1 And Xiap To Induce Apoptosis In Aml Cells.
- Simultaneous Knock-Down Of Bcl-Xl And Mcl-1 Induces Apoptosis In Gemcitabine-Sensitive And-Resistant Pancreatic Cancer Cells
- Simultaneous Knock-Down Of Bcl-Xl And Mcl-1 Induces Apoptosis Through Bax Activation In Pancreatic Cancer Cells
- Simultaneous Suppression Of Mcl-1 And Survivin Expression Via Rna Interference In Hl-60 Leukemia Cell Line
- Simultaneous Targeting Of Atm And Mcl-1 Increases Cisplatin Sensitivity Of Cisplatin-Resistant Non-Small Cell Lung Cancer
- Simvastatin Enhances Irinotecan-Induced Apoptosis In Prostate Cancer Via Inhibition Of Mcl-1
- Sindbis Viral Vector Induced Apoptosis Requires Translational Inhibition And Signaling Through Mcl-1 And Bak
- Sirt6 Is Upregulated And Associated With Cancer Aggressiveness In Papillary Thyroid Cancer Via Braf/Erk/Mclโ1 Pathway
- Small Interfering Rna Targeting Mcl-1 Enhances Proteasome Inhibitor-Induced Apoptosis In Various Solid Malignant Tumors
- Small Molecule Inhibitors Of Membrane-Bound Mcl-1 And Bcl-2.
- Small Molecule Mcl-1 Inhibitors For The Treatment Of Cancer
- Small Molecule Mcl-1 Inhibitors Induce Apoptosis And Death In Multiple Cancer Subtypes In Vitro
- Small Molecule Obatoclax (Gx15-070) Antagonizes Mcl-1 And Overcomes Mcl-1-Mediated Resistance To Apoptosis
- Small Molecules Targeting Mcl-1: The Search For A Silver Bullet In Cancer Therapy
- SmallโMolecule And Peptide Inhibitors Of The ProโSurvival Protein Mclโ1
- Small-Molecule Inhibitors Of The Mcl-1 Oncoprotein
- Small-Molecule Mcl-1 Inhibitors: Emerging Anti-Tumor Agents
- Sns-032, A Novel Inhibitor Of Cyclin-Dependent Kinases 2, 7 And 9, Blocks Transcription Of Cyclin D1 And Mcl-1, Causing Cell Death In Mantle Cell Lymphoma Cell โฆ
- Sodium Salicylate Promotes Neutrophil Apoptosis By Stimulating Caspase-Dependent Turnover Of Mcl-1
- Solution Structure Of Mcl-1 And Its Complexes
- Solution Structure Of Prosurvival Mcl-1 And Characterization Of Its Binding By Proapoptotic Bh3-Only Ligands
- Sorafenib Induces Cell Death In Chronic Lymphocytic Leukemia By Translational Downregulation Of Mcl-1
- Sorafenib Induces Endometrial Carcinoma Apoptosis By Inhibiting Elkโ1โDependent Mclโ1 Transcription And Inducing Akt/Gsk3ฮโDependent Protein Degradation
- Sorafenib Inhibition Of Mcl-1 Accelerates Atra-Induced Apoptosis In Differentiation-Responsive Aml Cells
- Sorafenib Inhibits In Vitro Osteoclastogenesis By Down-Modulating Mcl-1
- Sorafenib Plus Aspirin Promotes Trail-Induced Apoptosis By Targeting Flip And Mcl-1 And Potentiates Growth Inhibition In Colon Cancer Cells
- Sorafenib Sensitizes (โ)-Gossypol-Induced Growth Suppression In Androgen-Independent Prostate Cancer Cells Via Mcl-1 Inhibition And Bak Activation
- Sorafenib-Induced Apoptosis Of Chronic Lymphocytic Leukemia Cells Is Associated With Downregulation Of Raf And Myeloid Cell Leukemia Sequence 1 (Mcl-1)
- Sorafenib-Mediated Mcl-1 And Cflipl Down-Regulation Synergistically Increase Trail Lethality In Human Leukemia Cells
- Specific Cleavage Of Mcl-1 By Caspase-3 In Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (Trail)-Induced Apoptosis In Jurkat Leukemia T Cells
- Sphingosine 1-Phosphate Induces Mcl-1 Upregulation And Protects Multiple Myeloma Cells Against Apoptosis
- Sphingosine Kinase-1 Mediates Bcr/Abl-Induced Upregulation Of Mcl-1 In Chronic Myeloid Leukemia Cells
- Sphingosine-1-Phosphate Receptor S1P 1 Via Reciprocal Erk-Dependent Suppression Of Bim And Pi-3-Kinase/Protein Kinase C-Mediated Upregulation Of Mcl-1
- Spontaneous Oligomerization Of Bak/Bax Is Suppressed By Hetero-Dimerization With Mcl-1
- Stabilization And Enhancement Of The Antiapoptotic Activity Of Mcl-1 By Tctp
- Stapled Bh3 Peptides Against Mcl-1: Mechanism And Design Using Atomistic Simulations
- Stat3 And Mcl-1 Associate To Cause A Mesenchymal Epithelial Transition
- Stat3-And Gsk3ฮ-Mediated Mcl-1 Regulation Modulates Tpf Resistance In Oral Squamous Cell Carcinoma
- Stat3-Mediated Transcription Of Bcl-2, Mcl-1 And C-Iap2 Prevents Apoptosis In Polyamine-Depleted Cells
- Statins Enhance Killing Of Multiple Myeloma Cells By The Bcl-2 Inhibitor Venetoclax And The Mcl-1 Inhibitor S63845
- Staurosporine Resistance In Inflammatory Neutrophils Is Associated With The Inhibition Of CaspaseโAnd ProteasomeโMediated Mclโ1 Degradation
- Sti571 Induces Apoptosis Of K562 Cells Through Down-Regulation Of Anti-Apoptotic Protein Mcl-1 And Bcl-Xl Expression
- Strain-Specific Suppression Of Microrna-320 By Carcinogenic Helicobacter Pylori Promotes Expression Of The Antiapoptotic Protein Mcl-1
- Strong Correlation Between Vegf And Mcl-1 Mrna Expression Levels In B-Cell Chronic Lymphocytic Leukemia
- Structural Insights Into The Degradation Of Mcl-1 Induced By Bh3 Domains
- Structural Insights Into The Design Of Small Molecule Inhibitors That Selectively Antagonize Mcl-1
- Structural ReโEngineering Of The ฮโHelix Mimetic Jyโ1โ106 Into Small Molecules: Disruption Of The Mclโ1โBakโBh3 ProteinโProtein Interaction With 2, 6โDi โฆ
- Structure Based Design Of Non-Natural Peptidic Macrocyclic Mcl-1 Inhibitors
- Structure Of A Myeloid Cell Leukemia-1 (Mcl-1) Inhibitor Bound To Drug Site 3 Of Human Serum Albumin
- Structure Of The Bh3 Domains From The P53-Inducible Bh3-Only Proteins Noxa And Puma In Complex With Mcl-1
- Structure-Based Design And Development Of Pyrazolopyridine-Based Inhibitors Of Mcl-1
- Structure-Based Design And Synthesis Of Selective Small Molecule Inhibitors For Mcl-1, An Important Cancer Target
- Structure-Based Design Of 3-Carboxy-Substituted 1, 2, 3, 4-Tetrahydroquinolines As Inhibitors Of Myeloid Cell Leukemia-1 (Mcl-1)
- Structure-Based Design Of Inhibitors Of The Mcl-1 Oncoprotein
- Structure-Based Design Of N-Substituted 1-Hydroxy-4-Sulfamoyl-2-Naphthoates As Selective Inhibitors Of The Mcl-1 Oncoprotein
- Structure-Based Design, Synthesis And Evaluation Of Novel And Selective Small-Molecule Inhibitors Of The Anti-Apoptotic Protein Mcl-1.
- Structure-Function Analysis Of The Mcl-1 Protein Identifies A Novel Senescence-Regulating Domain
- Structure-Guided De Novo Design Of Selective Mcl-1 Inhibitors: Synthesis, Structural And Biochemical Characterization
- Structure-Guided Design Of A Series Of Mcl-1 Inhibitors With High Affinity And Selectivity
- Structure-Guided Design Of Pyridoclax Derivatives Based On Noxa/Mcl-1 Interaction Mode
- Structure-Guided Discovery Of A Selective Mcl-1 Inhibitor With Cellular Activity
- Structure-Guided Discovery Of Selective Mcl-1 Inhibitors
- Studies Of (E)-T-Butyl-2-((E)-2-Methyl-3-Phenylallylidene) Hydrazine Carboxylate And (E)-T-Butyl-2-((E)-3-Phenylallylidene) Hydrazine Carboxylates As A Possible Mcl-1 โฆ
- Studies Of The Role Of Mcl-1 In Haemopoiesis And Leukaemia
- Studies Of Tw-37, A New Nonpeptidic Small-Molecule Inhibitor Of Bcl-2, In Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action On Both Bcl-2 And Mcl-1
- Studies On The Role Of Bid And Mcl-1 In The Regulation Of Apoptosis.
- Study On Apoptosis Of Peripheral Neutrophil And Mcl-1, Caspase-3 Expression In Preeclamptic Patients
- Substituted Indole Mcl-1 Inhibitors: A Patent Evaluation (Wo2015148854A1)
- Sumoylation Site In Mcl-1 Regulates Its Anti-Apoptotic Activity
- Supplemental Data The Bh3 Mimetic Abt-737 Targets Selective Bcl-2 Proteins And Efficiently Induces Apoptosis Via Bak/Bax If Mcl-1 Is Neutralized
- Supplementary Figure 1| Knockdown Of Mcl-1 Sensitizes H196 Cells To Abt-737.
- Supplementary Materials: Role Of Non-Native Electrostatic Interactions In The Coupled Folding And Binding Of Puma With Mcl-1
- Suppression Of Mclโ1 Induces Apoptosis In Mouse Peritoneal Macrophages Infected With Mycobacterium Tuberculosis
- Suppression Of Mcl-1 Via Rna Interference Sensitizes Human Hepatocellular Carcinoma Cells Towards Apoptosis Induction
- Suppression Of Myeloid Cell Leukemia-1 (Mcl-1) Enhances Chemotherapy-Associated Apoptosis In Gastric Cancer Cells
- Suppression Of Pmn Apoptosis By Hypoxia Is Dependent On Mcl-1 And Mapk Activity
- Surface Plasmon Resonance Study Of Apoptotic Regulators Bcl-2, Bcl-W, Bcl-Xl, And Mcl-1 Indicate That The Preclinical Small Molecule Inhibitor (Smi) Tw-37 Binds To โฆ
- Surface Plasmon Resonance Study Of Apoptotic Regulators Bcl-2, Bcl-W, Bcl-Xl, Mcl-1 And A1 And The Small Molecule Inhibitor (Smi) Tw-37: The Idea Of A Temporal โฆ
- Survival Control Of Malignant Lymphocytes By Anti-Apoptotic Mcl-1
- Survival Factor Withdrawal-Induced Apoptosis Of Tf-1 Cells Involves A Trb2-Mcl-1 Axis-Dependent Pathway
- Survival Of Mycobacterium Tuberculosis In Host Macrophages Involves Resistance To Apoptosis Dependent Upon Induction Of Antiapoptotic Bcl-2 Family Member Mcl-1
- Survivin Inhibitor Ym-155 Sensitizes Trail-Resistant Glioma Cells To Apoptosis Through Mcl-1 Down-Regulation And By Engaging The Mitochondrial Death Pathway
- Sustained A1 And Mcl-1 Expression From Costimulatory Signals Promotes T Cell Survival (50.20)
- Sustained Signaling Through The B-Cell Receptor Induces Mcl-1 And Promotes Survival Of Chronic Lymphocytic Leukemia B Cells
- Sustained Signaling Through The B-Cell Receptor Induces Mcl-1 And Promotes Survival Of Chronic Lymphocytic Leukemia B-Cells.
- Syk Inhibition Disrupts The Cross-Talk Between B-Cell Activation Factor (Baff) And B-Cell Receptor (Bcr) And Thereby Antagonizes Mcl-1 In Chronic Lymphocytic โฆ
- Syk Inhibition Thwarts The Baff-B-Cell Receptor Crosstalk And Thereby Antagonizes Mcl-1 In Chronic Lymphocytic Leukemia
- Synergism Between P53 And Mcl-1 In Protecting From Hepatic Injury, Fibrosis And Cancer
- Synergistic Action Of The Mcl-1 Inhibitor S63845 With Current Therapies In Preclinical Models Of Triple-Negative And Her2-Amplified Breast Cancer
- Synergistic Activity Of The Mcl-1 Inhibitor S63845 With Midostaurin In Preclinical Human Models Of Flt3-Itd Mutated Acute Myeloid Leukemia (Aml)
- Synergistic Activity Of The Mcl-1-Specific Inhibitor S63845 With Venetoclax In B-Cell Precursor Acute Lymphoblastic Leukemia
- Synergistic Anti-Proliferative Effects Of Combination Of Abt-263 And Mcl-1 Selective Inhibitor A-1210477 On Cervical Cancer Cell Lines
- Synergistic Antitumor Activity Of Gemcitabine And Abt-737 In Vitro And In Vivo Through Disrupting The Interaction Of Usp9X And Mcl-1
- Synergistic Anti-Tumor Activity Of Mcl-1 Antisense Oligonucleotides And Docetaxel In Gastric Cancer Cells
- Synergistic Induction Of Apoptotic Cell Death In Aml By Targeting Bcl-2 With Abt-199 In Combination With Bcl-Xl/Mcl-1 Inhibition Or Selective Kinase Inhibitors
- Synergistic Interactions Between Vorinostat And Sorafenib In Chronic Myelogenous Leukemia Cells Involve Mcl-1 And P21Cip1 Down-Regulation
- Synthesis And Evaluation Of Substituted Hexahydronaphthalenes As Novel Inhibitors Of The Mcl-1/Bimbh3 Interaction
- Synthesis Of A Rhodanine-Based Compound Library Targeting Bcl-Xl And Mcl-1
- Synthesis Of Cell-Permeable Stapled Bh3 Peptide-Based Mcl-1 Inhibitors Containing Simple Aryl And Vinylaryl Cross-Linkers
- Tailored Fragments Of Roseophilin Selectively Antagonize Mcl-1 In Vitro
- Tankyrase 1 Interacts With Mcl-1 Proteins And Inhibits Their Regulation Of Apoptosis
- Tanshinone Iia Inhibits Human Gastric Carcinoma Ags Cell Growth By Decreasing Bip, Tctp, Mclโ1 And BclโXl And Increasing Bax And Chop Protein โฆ
- Tanshinone Iia Inhibits The Growth Of Pancreatic Cancer Bxpcโ3 Cells By Decreasing Protein Expression Of Tctp, Mclโ1 And BclโXl
- Targeted Delivery Of Ubiquitin-Conjugated Bh3 Peptide-Based Mcl-1 Inhibitors Into Cancer Cells
- Targeted Mcl-1 Inhibition To Induce Cell Death And Synergize With Conventional Chemotherapeutic Agents In Diffuse Large B-Cell Lymphoma (Dlbcl) Pre-Clinical โฆ
- Targeted Therapy: Sunitinib Modulates Mcl-1 And Mtor Signalling
- Targeting Acute Myeloid Leukemia By Dual Inhibition Of Pi3K Signaling And Cdk9-Mediated Mcl-1 Transcription
- Targeting Aml Through Apoptosis Activation Using Bcl-2/Mcl-1 Or Bcl-2/Hdm2 Inhibitor Combination Therapies
- Targeting Cdk9 And Mcl-1 By A New Cdk9/P-Tefb Inhibitor With And Without 5-Fluorouracil In Esophageal Adenocarcinoma
- Targeting Destruction Of Mcl-1 By Activation Of Protein Phosphatase 2A In Cll And B-Cell Lymphomas
- Targeting Flip And Mclโ1 Using A Combination Of Aspirin And Sorafenib Sensitizes Colon Cancer Cells To Trail
- Targeting Kpnb1 Overcomes Trail Resistance By Regulating Dr5, Mcl-1 And Flip In Glioblastoma Cells
- Targeting K-Ras, Pak-1, And Mcl-1 For The Treatment Of Cancer
- Targeting Mcl-1 And Bak As A Therapeutic Tool To Selectively Induce Apoptosis In Hepaptocellualr Carcinoma
- Targeting Mcl-1 And Other Bcl-2 Family Member Proteins In Cancer Therapy
- Targeting Mcl-1 By Proteasome Inhibitors Enhances The Anti-Tumor Activity Of Venetoclax In Mantle Cell Lymphoma Pre-Clinical Models
- Targeting Mcl-1 Enhances Dna Replication Stress Sensitivity To Cancer Therapy
- Targeting Mcl-1 Expression, Through The Inhibition Of Cdk9 And Super Enhancer Driven Transcription, Offers Multiple Opportunities For Rational Drug Combinations
- Targeting Mcl-1 For Multiple Myeloma (Mm) Therapy: Drug-Induced Generation Of Mcl-1 Fragment Mcl-1128โ350 Triggers Mm Cell Death Via C- Jun Upregulation
- Targeting Mcl-1 For Multiple Myeloma (Mm) Therapy: Drug-Induced Generation Of Mcl-1 Fragment Mcl-1128โ350 Triggers Mm Cell Death Via C-Jun Upregulation
- Targeting Mcl-1 For Radiosensitization Of Pancreatic Cancers
- Targeting Mcl-1 For The Therapy Of Cancer
- Targeting Mcl-1 Inhibits Survival And Self-Renewal Of Hepatocellular Cancer Stem-Like Cells
- Targeting Mcl-1 Regulated Apoptosis Pathway As A Novel Therapy In Pancreatic Cancer
- Targeting Mcl-1 Sensitizes Flt3-Itd-Positive Leukemias To Cytotoxic Therapies
- Targeting Mcl-1 Sensitizes Human Esophageal Squamous Cell Carcinoma Cells To Cisplatin-Induced Apoptosis
- Targeting Mcl-1/Bcl-Xl Forestalls The Acquisition Of Resistance To Abt-199 In Acute Myeloid Leukemia
- Targeting Of Mcl-1 Kills Myc-Driven Mouse And Human Lymphomas Even When They Bear Mutations In P53
- Targeting Sf3B1 Mediated Splicing Control Of Mcl-1 In Chronic Lymphocytic Leukemia
- Targeting The Anti-Apoptotic Protein Mcl-1 In Human Cancer
- Targeting The Apoptotic Mcl-1-Puma Interface With A Dual-Acting Compound
- Targeting The Bcl-2/Bh3 Protein-Protein Interaction: Identification, Design, And Synthesis Of New Selective Inhibitors Of The Mcl-1/Bh3 Interaction
- Targeting The Dna Repair As Well As Survival Functions Of Mcl-1 Enhances Cancer Cell Killing
- Targeting Tslp-Induce Upregulation Of Mcl-1 For The Treatment Of Ph-Like All With Crlf2 Alterations
- Taz Promotes Temozolomide Resistance By Upregulating Mcl-1 In Human Glioma Cells
- T-Cell Lymphoma And Adult T-Cell Leukemia/Lymphoma Cells Partially Depends On Up-Regulation Of Noxa, Functional Repression Of Mcl-1, And Down-Regulation Of โฆ
- Telomerase-Dependent Oncolytic Adenovirus Sensitizes Human Osteosarcoma Cells To Chemotherapy Through Mcl-1 Downregulation
- Tertiary Structural Motif Sequence Statistics Enable Facile Prediction And Design Of Peptides That Bind Anti-Apoptotic Bfl-1 And Mcl-1
- Tertiary Structural Motif Sequence Statistics Enable Rapid Discovery Of Novel Ligands For Anti-Apoptotic Bfl-1 And Mcl-1
- The Akt/Mcl-1 Pathway Plays A Prominent Role In Mediating Antiapoptotic Signals Downstream Of The B-Cell Receptor In Chronic Lymphocytic Leukemia B Cells
- The Akt/Mcl-1 Pathway Plays A Prominent Role In Mediating Pro-Survival Signals Derived From The B-Cell Receptor In Chronic Lymphocytic Leukemia B-Cells.
- The Anti-Apoptotic Bcl-2 Family Member Mcl-1 Promotes T Lymphocyte Survival At Multiple Stages
- The Antiapoptotic Effect Of Il-6 Autocrine Loop In A Cellular Model Of Advanced Prostate Cancer Is Mediated By Mcl-1
- The Anti-Apoptotic Effect Of Leukotriene B4 In Neutrophils: A Role For Phosphatidylinositol 3-Kinase, Extracellular Signal-Regulated Kinase And Mcl-1
- The Antiapoptotic Gene Mcl-1 Is Up-Regulated By The Phosphatidylinositol 3-Kinase/Akt Signaling Pathway Through A Transcription Factor Complex Containing Creb
- The Antiapoptotic Member Of The Bcl-2 Family Mcl-1 Is A Ctl Target In Cancer Patients
- The Antiapoptotic Protein Mcl-1 Controls The Type Of Cell Death In Theiler’S Virus-Infected Bhk-21 Cells
- The Anti-Apoptotic Protein Mcl-1 Inhibits Mitochondrial Ca2+ Signals
- The Anti-Apoptotic Protein Mcl-1 Is An Important Regulator Of Mitochondrial Turnover
- The Antiapoptotic Protein Mcl-1 Is Essential For The Survival Of Neutrophils But Not Macrophages
- The Anti-Apoptotic Protein Mcl-1 Is Overexpressed In Prostate Cancer
- The Anti-Apoptotic Role Of Interleukin-6 In Human Cervical Cancer Is Mediated By Up-Regulation Of Mcl-1 Through A Pi 3-K/Akt Pathway
- The Apoptosis And Proliferation Of Sac-Activated B Cells By Il-10 Are Associated With Changes In Bcl-2, Bcl-Xl, And Mcl-1 Expression
- The Apoptotic Response Of HighโGrade Serous Ovarian Cancers With Ccne1 Amplification To Paclitaxel In Vitro By Targeting Apc/C And The ProโSurvival Protein Mclโ1
- The Bcl-2 Family Members Mcl-1 And Bim Modulate Apoptosis In Glutamine-Deprived Sp2/0-Ag14 Mouse Cells
- The Bcl-2/Xl Inhibitor Abt-263 Increases The Stability Of Mcl-1 Mrna And Protein In Hepatocellular Carcinoma Cells
- The Bh3 Mimetic Abt-737 Targets Selective Bcl-2 Proteins And Efficiently Induces Apoptosis Via Bak/Bax If Mcl-1 Is Neutralized
- The Bh3 ฮ-Helical Mimic Bh3-M6 Disrupts Bcl-Xl, Bcl-2, And Mcl-1 Protein-Protein Interactions With Bax, Bak, Bad, Or Bim And Induces Apoptosis In A Bax-And Bim โฆ
- The Carboxyl-Terminal Tail Of Noxa Protein Regulates The Stability Of Noxa And Mcl-1
- The Cd44 Adhesion Molecule By The Antibody A3D8 Induces And Enhances Drug-Induced Apoptosis In Acute Myeloid Leukemia Cells Through Down-Regulation Of Mcl-1.
- The Cdk Inhibitor Purvalanol A Induces Neutrophil Apoptosis And Increases The Turnover Rate Of Mclโ1: Potential Role Of P38โMapk In Regulation Of Mclโ1 Turnover
- The Cdk Inhibitor, RโRoscovitine, Promotes Eosinophil Apoptosis By DownโRegulation Of Mclโ1
- The Cdk5-Mcl-1 Axis Promotes Mitochondrial Dysfunction And Neurodegeneration In A Model Of Alzheimer’S Disease
- The Cdk9 Inhibitor, Alvocidib, Potentiates The Non-Clinical Activity Of Azacytidine Or Decitabine In An Mcl-1-Dependent Fashion, Supporting Clinical Exploration Of A โฆ
- The Coffee Diterpene Kahweol Enhances Sensitivity To Sorafenib In Human Renal Carcinoma Caki Cells Through Down-Regulation Of Mcl-1 And C-Flip Expression
- The Combination Of Reduced Mcl-1 And Standard Chemotherapeutics Is Tolerable In Mice
- The Complex Mcl-1/Bim Regulates The Sensitivity Of Human Myeloma Cells To Melphalan.
- The Coordinated Neutralization Of Bcl-Xl And Mcl-1 By Abt-737 In Combination With Radiation Treatment Leads To Enhanced Cytotoxicity In Nsclc Cells
- The Cxcr4 Inhibitor Bl-8040 Induces The Apoptosis Of Aml Blasts By Downregulating Erk, Bcl-2, Mcl-1 And Cyclin-D1 Via Altered Mir-15A/16-1 Expression
- The Cyclin-Dependent Kinase Inhibitor Flavopiridol Induces Apoptosis In Multiple Myeloma Cells Through Transcriptional Repression And Down-Regulation Of Mcl-1
- The CyclinโDependent Kinase Inhibitor RโRoscovitine DownโRegulates Mclโ1 To Override ProโInflammatory Signalling And Drive Neutrophil Apoptosis
- The Cyclin-Dependent Kinase Inhibitor Sns-032 Induces Apoptosis In Breast Cancer Cells Via Depletion Of Mcl-1 And X-Linked Inhibitor Of Apoptosis Protein And โฆ
- The Design And Development Of Dual Mcl-1/Bcl-2 And Hdm2/Bcl-2 Protein Family Inhibitors Using A Polypharmacology Approach
- The Discovery Of Small Molecule Chemical Probes Of Bcl-Xl And Mcl-1
- The Downregulation Of Mcl-1 Via Usp9X Inhibition Sensitizes Solid Tumors To Bcl-Xl Inhibition
- The Drug Combination Sorafenib And Quinacrine Targets The Expression Of Mcl-1-An Anti-Apoptotic Protein And Candidate Prognostic Factor In Anaplastic Thyroid Cancer โฆ
- The Dual Effects Of Tnfฮฑ On Neutrophil Apoptosis Are Mediated Via Differential Effects On Expression Of Mcl-1 And Bfl-1
- The E3 Ubiquitin Ligases ฮ-Trcp And Fbxw7 Cooperatively Mediates Gsk3-Dependent Mcl-1 Degradation Induced By The Akt Inhibitor Api-1, Resulting In โฆ
- The Eat/Mcl-1 Gene, An Inhibitor Of Apoptosis, Is Up-Regulated In The Early Stage Of Acute Myocardial Infarction
- The Effect Of N-Nitrosodimethylamine (Ndma) On Bax And Mcl-1 Expression In Human Neutrophils
- The Effects Of Lentivirus-Mediated Shrna Interference Targeting Mcl-1 On Growth Of Nk/T-Cell Lymphoma.
- The Effects Of Mcl-1 Gene On Atra-Resistant Hl-60 Cell
- The Effects Of Thymoquinone On Viability, And Anti-Apoptotic Factors (Bcl-Xl, Bcl-2, Mcl-1) In Prostate Cancer (Pc3) Cells: An In Vitro And Computer โฆ
- The Enteroviral Capsid Protein Vp1 In The Islet Cells Of Patients With Type 1 Diabetes Is Associated With Induction Of Protein Kinase R And Downregulation Of Mcl-1
- The Expression And Clinical Significances Of Mcl-1 In Cervical Cancer
- The Expression Of Antiapoptotic Proteins Bcl-2, Bcl-Xl, And Mcl-1 In Benign, Dysplastic, And Malignant Biliary Epithelium
- The Expression Of Cox-2 In Human Lung Cancer And Its Relationship With Expression Of K-Ras And Mcl-1.
- The Expression Of Mcl-1 In Human Cervical Cancer And Its Clinical Significance
- The Expressions And Clinical Significance Of Mcl-1 And Bar/Abl Genes In Chronic Myeloid Leukemia
- The Fast-Mobility Isoform Of Mouse Mcl-1 Is A Mitochondrial Matrix-Localized Protein With Attenuated Anti-Apoptotic Activity
- The First Mcl-1-Selective Bh3 Mimetics Have Therapeutic Potential For Chronic Lymphocytic Leukemia
- The Foxm1-Induced Resistance To Oxaliplatin Is Partially Mediated By Its Novel Target Gene Mcl-1 In Gastric Cancer Cells
- The Functional Role Of Mcl-1 In The Dynamics Of Mitotic Cell Fate.
- The Hepatitis C Virus Core Protein Contains A Bh3 Domain That Regulates Apoptosis Through Specific Interaction With Human Mcl-1
- The Human Stem Cell Hierarchy Is Defined By A Functional Dependence On Mcl-1 For Self-Renewal Capacity
- The Imbalance Between Bim And Mclโ1 Expression Controls The Survival Of Human Myeloma Cells
- The Intracellular Distribution And Pattern Of Expression Of Mcl-1 Overlap With, But Are Not Identical To, Those Of Bcl-2.
- The Involvement Of Pi 3-K/Akt-Dependent Up-Regulation Of Mcl-1 In The Prevention Of Apoptosis Of Hep3B Cells By Interleukin-6
- The Kit D816V-Targeting Drug Pkc412 Induces Re-Expression Of Bim And Synergizes With Mcl-1 Antisense Oligonucleotides In Producing Growth Inhibition In โฆ
- The Lnc Rna Malat 1 Functions As A Competing Endogenous Rna To Regulate Mclโ1 Expression By Sponging Mirโ363โ3P In Gallbladder Cancer
- The Loss Of Mclโ1 Expression In Human Polymorphonuclear Leukocytes Promotes Apoptosis
- The Mcl-1 Bh3 Helix Is An Exclusive Mcl-1 Inhibitor And Apoptosis Sensitizer
- The Mcl-1 Targeting Effect Of Alvocidib Potentiates The Activity Of Cytarabine And Mitoxantrone In A Time-Sequential Regimen In Aml
- The Mtorc1/2 Inhibitor Azd8055 Strengthens The Efficiency Of The Mek Inhibitor Trametinib To Reduce The Mcl-1/[Bim And Puma] Ratio And To Sensitize Ovarian โฆ
- The Multikinase Inhibitor Sorafenib Potentiates Trail Lethality In Human Leukemia Cells In Association With Mcl-1 And Cflipl Down-Regulation
- The MultiโKinase Inhibitor Tg 02 Overcomes Signalling Activation By Survival Factors To Deplete Mcl 1 And Xiap And Induce Cell Death In Primary Acute Myeloid โฆ
- The N Terminus Of The Anti-Apoptotic Bcl-2 Homologue Mcl-1 Regulates Its Localization And Function
- The Novel Atp-Competitive Mek/Aurora Kinase Inhibitor Bi-847325 Overcomes Acquired Braf Inhibitor Resistance Through Suppression Of Mcl-1 And Mek Expression
- The Novel Bmi-1 Inhibitor Ptc596 Downregulates Mcl-1 And Induces P53-Independent Mitochondrial Apoptosis In Acute Myeloid Leukemia Progenitor Cells
- The Novel Cancer Drug Seliciclib Engages The Mitochondrial Apoptosis Pathway Via The Mcl-1/Noxa Axis In Cll.
- The Noxa, Bim And Mcl-1 Axis Mediates Apoptosis In Response To General Metabolic Stress
- The Noxa/Mcl-1 Axis Regulates Susceptibility To Apoptosis Under Glucose Limitation In Dividing T Cells
- The Phosphotidyl Inositol 3-Kinase/Akt Signal Pathway Is Involved In Interleukin-6-Mediated Mcl-1 Upregulation And Anti-Apoptosis Activity In Basal Cell โฆ
- The Pi3 Kinase Inhibitor Nvp-Bkm120 Induces Gsk3/Fbxw7-Dependent Mcl-1 Degradation, Contributing To Induction Of Apoptosis And Enhancement Of Trail โฆ
- The Polyamines Regulate Endothelial Cell Survival During Hypoxic Stress Through Pi3K/Akt And Mcl-1
- The Possible Role Of Apoptosis-Suppressing Genes, Bcl-2 And Mcl-1/Eat In Human Adrenal Tumors
- The Protein Kinase Cฮด Catalytic Fragment Targets Mcl-1 For Degradation To Trigger Apoptosis
- The Raf Kinase Inhibitor Bay 43-9006 Accelerates Mcl-1 Degradation And Regulates Pro-Apoptotic Function
- The Ratio Of Mcl-1 And Noxa Determines Abt737 Resistance In Squamous Cell Carcinoma Of The Skin
- The Regulatory Role Of Mcl-1 In Apoptosis Of Mouse Peritoneal Macrophage Infected With M. Tuberculosis Strains That Differ In Virulence
- The Relationship Between The Expression Of Mcl-1, Bax And Histologic Grade, Prognosis In Human Hepatocellular Carcinoma
- The Relevance Of Sequence Insertions In The Mcl-1 Promoter In Chronic Lymphocytic Leukemia And In Normal Cells
- The Role Of Glucocorticoid Receptor Phosphorylation In Mcl-1 And Noxa Gene Expression
- The Role Of Hectd1 And Mcl-1 In The Regulation Of Normal And Malignant Haematopoiesis
- The Role Of Mcl-1 Downregulation In The Proapoptotic Activity Of The Multikinase Inhibitor Bay 43-9006
- The Role Of Mcl-1 Expression And Phosphorlyation In Resistance To Chemotherapy And Kinase Inhibitors In Flt3-Itd-Positive Acute Myeloid Leukemia (Aml)
- The Role Of Mcl-1 In S. Aureus-Induced Cytoprotection Of Infected Macrophages
- The Role Of Mcl-1 In The Heart: Gateway From Life To Death
- The Role Of Mcl-1 In The Response Of Human Colorectal Cancer Cells To Treatment With Dichloroacetate
- The Role Of Noxa/Mcl-1 Axis In Solid Tumors Treated With Dna Damaging Agents
- The Role Of Noxa/Mcl-1 In Head And Neck Squamous Cell Carcinoma (Hnscc) Treatment
- The Roles Of Mcl-1 And Bcl-X In Central Nervous System Development
- The Roles Of The Anti-Apoptotic Proteins Bcl-2 And Mcl-1 In The Survival Of The Cells Of The Immune System
- The Secret Of Mim: A Novel, Mcl-1-Specific Small Molecule
- The Sensitivity Of Ovarian Cancer Cells To The Hdac Inhibitor Belinostat Is Improved By Inhibiting Bcl-Xl Or Mcl-1 Anti-Apoptotic Proteins
- The Sf3B1 Inhibitor Spliceostatin A (Ssa) Elicits Apoptosis In Chronic Lymphocytic Leukaemia Cells Through Downregulation Of Mcl-1
- The Small Molecule Bcl-2/Mcl-1 Inhibitor Tw-37 Shows Single-Agent Cytotoxicity In Neuroblastoma Cell Lines
- The Stress Protein Bag3 Stabilizes Mcl-1 Protein And Promotes Survival Of Cancer Cells And Resistance To Antagonist Abt-737
- The Study Of The Effect Of Curcumin On Apoptosis-Regulating Protein Mcl-1, Bax And Bak In Acute Myeloid Leukemia Hl-60 Cell Line
- The Tyrosine Kinase Syk Regulates Survival Of Chronic Lymphocytic Leukemia B Cells Through Pkcฮด Phosphorylation And Proteasome-Dependent Regulation Of Mcl-1 โฆ
- The Tyrosine Kinase Syk Regulates The Survival Of Chronic Lymphocytic Leukemia B Cells Through Pkcฮด And Proteasome-Dependent Regulation Of Mcl-1 โฆ
- The Vtlisfg Motif In The Bh1 Domain Plays A Significant Role In Regulating The Degradation Of Mcl-1
- Therapeutic Efficacy Of Mcl-1 Antagonism In Large Granular Lymphocyte Leukemia
- Therapeutic Inhibition Of Mcl-1 Blocks Cell Survival In Estrogen Receptor-Positive Breast Cancers
- Therapeutic Potential Of Bcl-Xl/Mcl-1 Synthetic Inhibitor Jy-1-106 And Retinoids For Human Triple-Negative Breast Cancer Treatment
- Thioridazine Enhances Sensitivity To Carboplatin In Human Head And Neck Cancer Cells Through Downregulation Of C-Flip And Mcl-1 Expression
- Thr 163 Phosphorylation Causes Mcl-1 Stabilization When Degradation Is Independent Of The Adjacent Gsk3-Targeted Phosphodegron, Promoting Drug โฆ
- Thymic Stromal Lymphopoietin Interferes With The Apoptosis Of Human Skin Mast Cells By A Dual Strategy Involving Stat5/Mcl-1 And Jnk/Bcl-Xl
- Tic10/Onc201 Synergizes With Bcl-2/Bcl-Xl Inhibition In Glioblastoma By Suppression Of Mcl-1 And Its Binding Partners In Vitro And In Vivo
- Timed Degradation Of Mcl-1 Controls Mitotic Cell Death
- Tipping The Noxa/Mcl-1 Balance Overcomes Abt-737 Resistance In Chronic Lymphocytic Leukemia
- Titelbild: Deactivation Of Mclโ1 By DualโFunction SmallโMolecule Inhibitors Targeting The Bclโ2 Homology 3 Domain And Facilitating Mclโ1 Ubiquitination (Angew โฆ
- Tivantinib (Arq 197) Affects The Apoptotic And Proliferative Machinery Downstream Of C-Met: Role Of Mcl-1, Bcl-Xl And Cyclin B1
- Tlr9 Signaling Delays Neutrophil Apoptosis By Increasing Transcription Of Mcl-1
- Tofa (5-Tetradecyl-Oxy-2-Furoic Acid) Reduces Fatty Acid Synthesis, Inhibits Expression Of Ar, Neuropilin-1 And Mcl-1 And Kills Prostate Cancer Cells Independent Of P53 โฆ
- Toll-Like Receptor 9 Signaling Delays Neutrophil Apoptosis By Increasing Transcription Of Mcl-1
- Toward Targeting Antiapoptotic Mcl-1 For Cancer Therapy
- Toward Understanding Mcl-1 Promiscuous And Specific Binding Mode
- Toxoplasma Gondii Induces Autophagy And Apoptosis In Human Umbilical Cord Mesenchymal Stem Cells Via Downregulation Of Mclโ1
- Tp53 Deficient/Mutant Amls Are Resistant To Individual Bh3 Mimetics: High Efficacy Of Combined Inhibition Of Bcl-2 And Mcl-1
- Trail And Proteasome Inhibitors Combination Induces A Robust Apoptosis In Human Malignant Pleural Mesothelioma Cells Through Mcl-1 And Akt Protein โฆ
- Trail Enhances Proteasome Inhibitor-Induced Apoptosis In Human Malignant Pleural Mesothelioma Cells Through Promoting Caspase Activation And Mcl-1 โฆ
- Trail Resistance Through Transcriptional Control Of Mcl-1
- Trail-Activated Stress Kinases Suppress Apoptosis Through Transcriptional Upregulation Of Mcl-1
- Trailr Triggering By Human Antibodies Induces Apoptosis Through An Early Cleavage Of Mcl-1 And Caspase 3 In Myeloma Cells.
- Transcriptional And Translational Control Of Mcl-1 During Apoptosis
- Transcriptional Regulation Of Mcl-1 Plays An Important Role Of Cellular Protective Effector Of Vincristine-Triggered Autophagy In Oral Cancer Cells
- Transcriptional Silencing Of Mcl-1 Through Cyclin-Dependent Kinase Inhibition In Acute Myeloid Leukemia
- Translation Inhibition During Cell Cycle Arrest And Apoptosis: Mcl-1 Is A Novel Target For Rna Binding Protein Cugbp2
- Translation Inhibitors Induce Cell Death By Multiple Mechanisms And Mcl-1 Reduction Is Only A Minor Contributor
- Translational Repression Of Mcl-1 Couples Stress-Induced Eif2ฮ Phosphorylation To Mitochondrial Apoptosis Initiation
- Treatment With Homoharringtonine Reduces Levels Of Bcr-Abl, Mcl-1, And Hsp90 In Leukemia Cell Lines And The Survival Of Leukemic Stem Cells
- Trichomonas Vaginalis Promotes Apoptosis Of Human Neutrophils By Activating Caspaseโ3 And Reducing Mclโ1 Expression
- Trichonomas Vaginalis Metalloproteinase Induces Apoptosis Of Siha Cells Through Disrupting The Mcl-1/Bim And Bcl-Xl/Bim Complexes
- Trim17-Mediated Ubiquitination And Degradation Of Mcl-1 Initiate Apoptosis In Neurons
- Triptolide Induces Apoptotic Cell Death Of Multiple Myeloma Cells Via Transcriptional Repression Of Mcl-1
- Tsc2+/-Eฮผ-Myc Tsc2+/-Eฮผ-Myc Shfluc. 1309 Mcl-1 Shbim. 764 Shbim. 825
- Tyrosine Kinase Inhibitor (Tki) Exel-0862 Potently Induces Apoptosis In Human Fip1L1-Pdgfr-ฮ-Expressing Cells Through Caspase-Dependent Cleavage Of Mcl-1 โฆ
- Tyrosine Kinase Inhibitor Tyrphostin Ag490 Triggers Both Apoptosis And Autophagy By Reducing Hsf1 And Mcl-1 In Pel Cells
- Ubiquitin-Independent Degradation Of Antiapoptotic Mcl-1
- Umi-77 Primes Glioma Cells For Trail-Induced Apoptosis By Unsequestering Bim And Bak From Mcl-1
- Understanding Bcl-Xl And Mcl-1 Gain-Of-Function (Gof) Inhibition Mechanism In Relation To Mitochondrial Metabolic Changes
- Understanding The Species Selectivity Of Myeloid Cell Leukemia-1 (Mcl-1) Inhibitors
- Unexpected Complexity In Mcl-1 Phosphorylation In Response To Microtubule Inhibitors.
- Unique Biology Of Mcl-1: Therapeutic Opportunities In Cancer
- Unraveling Mcl-1 Degradation
- Up-Regulation Of Cdk9 Kinase Activity And Mcl-1 Stability Contributes To The Acquired Resistance To Cyclin-Dependent Kinase Inhibitors In Leukemia
- Upregulation Of Mapk/Mcl-1 Maintaining Mitochondrial Oxidative Phosphorylation Confers Acquired Resistance To Bcl-2 Inhibitor Venetoclax In Aml
- Up-Regulation Of Mcl-1 And Bak By Coronavirus Infection Of Human, Avian And Animal Cells Modulates Apoptosis And Viral Replication
- Upregulation Of Mcl-1 Inhibits Jq1-Triggered Anticancer Activity In Hepatocellular Carcinoma Cells
- Up-Regulation Of Mcl-1 Is Critical For Survival Of Human Melanoma Cells Upon Endoplasmic Reticulum Stress
- Up-Regulation Of Pro-Apoptotic Protein Bim And Down-Regulation Of Anti-Apoptotic Protein Mcl-1 Cooperatively Mediate Enhanced Tumor Cell Death Induced By The โฆ
- Ursolic Acid Facilitates Apoptosis In Rheumatoid Arthritis Synovial Fibroblasts By Inducing Sp1-Mediated Noxa Expression And Proteasomal Degradation Of Mcl-1
- Use Of A Mcl-1 Inhibitor Alone To De-Bulk Melanoma And In Combination To Kill Melanoma Initiating Cells
- Using Cetsa Assay And A Mathematical Model To Reveal Dual Bcl-2/Mcl-1 Inhibition And On-Target Mechanism For Abt-199 And S1
- Usp9X-And Noxa-Mediated Mcl-1 Downregulation Contributes To Pemetrexed-Induced Apoptosis In Human Non-Small-Cell Lung Cancer Cells
- Vaccinia Virus F1L Interacts With Bak Using Highly Divergent Bcl-2 Homology Domains And Replaces The Function Of Mcl-1
- Vascular Endothelial Growth Factor (Vegf) Is A Survival Factor In Metastatic Human Prostate Cancer Cells Via Induction Of Myeloid Cell Leukemia-1 (Mcl-1)
- Vegf Induces Mcl-1 Up-Regulation And Protects Multiple Myeloma Cells Against Apoptosis
- Vegf Upregulates Mcl-1 Expression And Protects Multiple Myeloma Cells Against Starvation Induced-Apoptosis.
- Vesicular Stomatitis Virus Induces Apoptosis Primarily Through Bak Rather Than Bax By Inactivating Mcl-1 And Bcl-Xl
- Vinblastine Induces Acute, Cell Cycle PhaseโIndependent Apoptosis In Some Leukemias And Lymphomas And Can Induce Acute Apoptosis In Others When Mcl-1 Is โฆ
- Vinca Alkaloids Cause Aberrant Ros-Mediated Jnk Activation, Mcl-1 Downregulation, Dna Damage, Mitochondrial Dysfunction, And Apoptosis In Lung Adenocarcinoma โฆ
- Virtual Screening For Inhibitors Of Anti-Apoptotic Proteins: Dck, Bcl-Xl, Mcl-1, Mdmx, And Mdm2
- Virtual Screening For Potential Inhibitors Of Mcl-1 Conformations Sampled By Normal Modes, Molecular Dynamics, And Nuclear Magnetic Resonance
- Virtual Screening, Docking Study And Molecular Dynamics (Md) Simulation Approach To Identify Inhibitors With Novel Scaffolds For Myeloid Cell Leukemia (Mcl-1 โฆ
- Voruciclib, A Clinical Stage Oral Cdk9 Inhibitor, Represses Mcl-1 And Sensitizes High-Risk Diffuse Large B-Cell Lymphoma To Bcl2 Inhibition
- Vsv Virotherapy Improves Chemotherapy By Triggering Apoptosis Due To Proteasomal Degradation Of Mcl-1
- Vsv Virotherapy Of Tumors Enhances Chemotherapeutic Efficacy By Proteasomal Degradation Of Mcl-1
- Wee-1 Kinase Inhibition Sensitizes High-Risk Hpv+ Hnscc To Apoptosis Accompanied By Downregulation Of Mcl-1 And Xiap Antiapoptotic Proteins
- Weight Glycoprotein Fraction From Ganoderma Lucidum Inhibits The Akt Pathway In Resistant Myeloma Cell Lines Decreasing Mcl-1 Expression, Up-Regulating Fkhr โฆ
- Wogonin And Related Natural Flavones Are Inhibitors Of Cdk9 That Induce Apoptosis In Cancer Cells By Transcriptional Suppression Of Mcl-1
- Xanthohumol Induces Apoptosis In B-Cll Mediated By Caspase 9 Following Downregulation Of Bcl-Xl And Mcl-1.
- Xpo1 Inhibitor Kpt-330 Synergizes With Bcl-Xl Inhibitor To Induce Cancer Cell Apoptosis By Perturbing Rrna Processing And Mcl-1 Protein Synthesis
- Ym155 Enhances Abt-737-Mediated Apoptosis Through Mcl-1 Downregulation In Mcl-1-Overexpressed Cancer Cells
- Ym155 Exerts Potent Cytotoxic Activity Against Quiescent (G0/G1) Multiple Myeloma And Bortezomib Resistant Cells Via Inhibition Of Mcl-1 And Survivin
- Ym155 Exerts Potent Cytotoxic Activity Against Quiescent (G0/G1) Multiple Myeloma And Bortezomib Resistant Cells Via Inhibition Of Survivin And Mcl-1
- Ym155 Induces Apoptosis Through Proteasome-Dependent Degradation Of Mcl-1 In Primary Effusion Lymphoma
- Ym155 Induces Caspase-8 Dependent Apoptosis Through Downregulation Of Survivin And Mcl-1 In Human Leukemia Cells
- Ym-155 Potentiates The Effect Of Abt-737 In Malignant Human Glioma Cells Via Survivin And Mcl-1 Downregulation In An Egfr-Dependent Context
- Ym-155 Sensitizes Malignant Human Glioma Cells To Abt-737 Via Survivin And Mcl-1 Downregulation In An Egfr-Dependent Context.
- Ym155 Sensitizes Trail-Induced Apoptosis Through Cathepsin S-Dependent Down-Regulation Of Mcl-1 And Nf-ฮb-Mediated Down-Regulation Of C-Flip โฆ
- Zoledronic Acid Increases Docetaxel Cytotoxicity Through Pmek And Mcl-1 Inhibition In A Hormone-Sensitive Prostate Carcinoma Cell Line
- ฮ-Tocopherol Impairs 7-Ketocholesterol-Induced Caspase-3-Dependent Apoptosis Involving Gsk-3 Activation And Mcl-1 Degradation On 158N Murine Oligodendrocytes
- ฮarrestin-1 And Mcl-1 Modulate Self-Renewal Growth Of Cancer Stem-Like Side-Population Cells In Non-Small Cell Lung Cancer
