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    DEPERSONALIZATION
    August 3, 2022
    POLYPHENOLS AS COVID-19 TREATMENT & PREVENTION
    August 3, 2022
    1. Oxidative stress, toxicology, and pharmacology of CYP2E1
    2. Genetic polymorphism in CYP2E1: Population distribution of CYP2E1 activity
    3. CYP2E1 and oxidative liver injury by alcohol
    4. Human CYP2E1 is regulated by miR-378
    5. Role of CYP2E1 in the Hepatotoxicity of Acetaminophen (∗)
    6. CYP2E1
    7. CYP2E1: from ash to nash
    8. Human hepatic CYP2E1 expression during development
    9. Ethanol Induces CYP2E1 by Protein Stabilization: ROLE OF UBIQUITIN CONJUGATION IN THE RAPID DEGRADATION OF CYP2E1 (∗)
    10. Role of CYP2E1 in Diethylnitrosamine-Induced Hepatocarcinogenesis In vivo
    11. CYP2E1-dependent toxicity and oxidative stress in HepG2 cells
    12. Different regulation and expression of the human CYP2E1 gene due to the Rsal polymorphism in the 5′-flanking region
    13. Insulin signaling in the transcriptional and posttranscriptional regulation of CYP2E1 expression
    14. The CYP2E1-humanized transgenic mouse: role of CYP2E1 in acetaminophen hepatotoxicity
    15. Role of cytochromes P450 in chemical toxicity and oxidative stress: studies with CYP2E1
    16. Genetic polymorphism of human CYP2E1: characterization of two variant alleles
    17. Increased hepatocyte CYP2E1 expression in a rat nutritional model of hepatic steatosis with inflammation
    18. Reduction of benzene metabolism and toxicity in mice that lack CYP2E1 expression
    19. CYP2E1 genetic polymorphisms and risk of nasopharyngeal carcinoma in Taiwan
    20. CYP2E1 and risk of chemically mediated cancers
    21. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1
    22. Resistance to carbon tetrachloride-induced hepatotoxicity in mice which lack CYP2E1 expression
    23. CYP2E1 mediated isoniazid-induced hepatotoxicity in rats
    24. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1.
    25. CYP2E1 is not involved in early alcohol-induced liver injury
    26. Ethnic variation in the CYP2E1 gene: polymorphism analysis of 695 African-Americans, European-Americans and Taiwanese.
    27. Detection and characterization of novel polymorphisms in the CYP2E1 gene.
    28. Contribution of CYP2E1 and CYP3A to acetaminophen reactive metabolite formation
    29. CYP2E1: biochemistry, toxicology, regulation and function in ethanol-induced liver injury
    30. Chlorzoxazone, a selective probe for phenotyping CYP2E1 in humans.
    31. CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
    32. Genetic and dietary predictors of CYP2E1 activity: a phenotyping study in Hawaii Japanese using chlorzoxazone
    33. CYP2E1—biochemical and toxicological aspects and role in alcohol-induced liver injury
    34. CYP2E1 activity before and after weight loss in morbidly obese subjects with nonalcoholic fatty liver disease
    35. Developmental Expression of CYP2E1 in the Human Liver: Hypermethylation Control of Gene Expression During the Neonatal Period
    36. Role of CYP2E1 in thioacetamide-induced mouse hepatotoxicity
    37. The alcohol-inducible form of cytochrome P450 (CYP2E1): role in toxicology and regulation of expression
    38. Protection against acetaminophen toxicity in CYP1A2 and CYP2E1 double-null mice
    39. The impact of CYP2E1 on the development of alcoholic liver disease as studied in a transgenic mouse model
    40. Oxidative stress mediated toxicity exerted by ethanol-inducible CYP2E1
    41. Hepatocyte CYP2E1 overexpression and steatohepatitis lead to impaired hepatic insulin signaling
    42. Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half …
    43. Development and properties of HepG2 cells that constitutively express CYP2E1
    44. Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol
    45. CYP2E1 genotype and isoniazid-induced hepatotoxicity in patients treated for latent tuberculosis
    46. Human CYP2E1 mediates the formation of glycidamide from acrylamide
    47. Role of CYP2E1 in the epoxidation of acrylamide to glycidamide and formation of DNA and hemoglobin adducts
    48. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
    49. Brain CYP2E1 is induced by nicotine and ethanol in rat and is higher in smokers and alcoholics
    50. Iron and CYP2E1-dependent oxidative stress and toxicity
    51. Genetic polymorphisms of NAT2 and CYP2E1 associated with antituberculosis drug-induced hepatotoxicity in Korean patients with pulmonary tuberculosis
    52. Role of CYP2E1 in ethanol-induced oxidant stress, fatty liver and hepatotoxicity
    53. Biotransformation of caffeine, paraxanthine, theobromine and theophylline by cDNA-expressed human CYP1A2 and CYP2E1.
    54. Diallylsulfide and allylmethylsulfide are uniquely effective among organosulfur compounds in inhibiting CYP2E1 protein in animal models
    55. CYP2E1‐mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells
    56. In vivo and in vitro characterization of CYP2E1 activity in Japanese and Caucasians.
    57. CYP2E1-dependent toxicity and up-regulation of antioxidant genes
    58. Metabolic activation of dacarbazine by human cytochromes P450: the role of CYP1A1, CYP1A2, and CYP2E1
    59. Polymorphisms in GSTT1, GSTZ1, and CYP2E1, Disinfection By-products, and Risk of Bladder Cancer in Spain
    60. Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1
    61. Mechanisms of down-regulation of CYP2E1 expression by inflammatory cytokines in rat hepatoma cells
    62. Absence of acrylamide-induced genotoxicity in CYP2E1-null mice: evidence consistent with a glycidamide-mediated effect
    63. Advances in the interpretation and prediction of CYP2E1 metabolism from a biochemical perspective
    64. Role of NQO1, MPO and CYP2E1 genetic polymorphisms in the susceptibility to childhood acute lymphoblastic leukemia
    65. Cytochrome P450IIE1 (CYP2E1) is induced by skatole and this induction is blocked by androstenone in isolated pig hepatocytes
    66. Association of CYP2E1 gene polymorphism with predisposition to cancer development
    67. CYP2E1 substrate inhibition: Mechanistic interpretation through an effector site for monocyclic compounds
    68. Transcriptional control of the rat hepatic CYP2E1 gene
    69. Transcriptional control of CYP2E1 in the perivenous liver region and during starvation
    70. Mechanism-based inactivation of human CYP2E1 by diethyldithocarbamate
    71. Nrf2 and antioxidant defense against CYP2E1 toxicity
    72. Acetaldehyde as well as ethanol is metabolized by human CYP2E1
    73. NAT2 and CYP2E1 polymorphisms and susceptibility to first-line anti-tuberculosis drug-induced hepatitis
    74. Associations of CYP1A1, GSTM1, and CYP2E1 Polymorphisms with Lung Cancer Suggest Cell Type Specificities to Tobacco Carcinogens
    75. Pharmacokinetic consequences of induction of CYP2E1 by ligand stabilization
    76. Activity of CYP2E1 and CYP3A enzymes in adults with moderate alcohol consumption: a comparison with nonalcoholics
    77. Loss of CYP2E1 and CYP1A2 activity as a function of acetaminophen dose: relation to toxicity
    78. Acetone catabolism by cytochrome P450 2E1: studies with CYP2E1-null mice
    79. Genetic polymorphisms of CYP2E1, GSTM1, and GSTT1; environmental factors and risk of oral cancer.
    80. Regulation of CYP2E1 by ethanol and palmitic acid and CYP4A11 by clofibrate in primary cultures of human hepatocytes
    81. Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1
    82. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1
    83. CYP2E1 enhances ethanol-induced lipid accumulation but impairs autophaghy in HepG2 E47 cells
    84. Effects of rifampin on CYP2E1-dependent hepatotoxicity of isoniazid in rats
    85. CYP2E1 activity in patients with alcoholic liver disease
    86. Mitochondrial CYP2E1 is sufficient to mediate oxidative stress and cytotoxicity induced by ethanol and acetaminophen
    87. CYP2E1-dependent oxidative stress and toxicity: role in ethanol-induced liver injury
    88. Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats
    89. CYP2E1-mediated modulation of valproic acid-induced hepatocytotoxicity
    90. Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Cancer: The Fukuoka Colorectal Cancer Study
    91. Genetic polymorphism of GSTM1, CYP2E1 and CYP2D6 in Egyptian bladder cancer patients
    92. Cytochrome P450 2E1 (CYP2E1) is essential for acrylonitrile metabolism to cyanide: comparative studies using CYP2E1-null and wild-type mice
    93. Inhibition of CYP3A, CYP1A and CYP2E1 activities by resveratrol and other non volatile red wine components
    94. Expression of CYP2E1 during human fetal development: methylation of the CYP2E1 gene in human fetal and adult liver samples
    95. CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of γ-glutamylcysteine synthetase
    96. Genetic polymorphisms of NAT2, CYP2E1 and GST enzymes and the occurrence of antituberculosis drug-induced hepatitis in Brazilian TB patients
    97. Genotype and allele frequencies of polymorphic CYP2E1 in the Turkish population
    98. The FANCG Fanconi anemia protein interacts with CYP2E1: possible role in protection against oxidative DNA damage
    99. Ethanol induction of CYP2A5: permissive role for CYP2E1
    100. Allylnitrile metabolism by CYP2E1 and other CYPs leads to distinct lethal and vestibulotoxic effects in the mouse
    101. CYP2E1 and catalase influence ethanol sensitivity in the central nervous system
    102. Acetaldehyde as a substrate for ethanol-inducible cytochrome P450 (CYP2E1)
    103. Cytochrome P450 2E1 (CYP2E1) is the principal enzyme responsible for urethane metabolism: comparative studies using CYP2E1-null and wild-type mice
    104. CYP1A1, CYP2E1 and GSTM1 genetic polymorphisms. The effect of single and combined genotypes on lung cancer susceptibility in Chilean people
    105. Red Meat Intake, CYP2E1 Genetic Polymorphisms, and Colorectal Cancer Risk
    106. Molecular mechanism of trichloroethylene-induced hepatotoxicity mediated by CYP2E1
    107. Comparison of germ cell mutagenicity in male CYP2E1-null and wild-type mice treated with acrylamide: evidence supporting a glycidamide-mediated effect
    108. Low doses of nicotine and ethanol induce CYP2E1 and chlorzoxazone metabolism in rat liver
    109. Role of CYP3A and CYP2E1 in alcohol-mediated increases in acetaminophen hepatotoxicity: comparison of wild-type and CYP2E1 (–/–) mice
    110. Insulin effects on CYP2E1, 2B, 3A, and 4A expression in primary cultured rat hepatocytes
    111. Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione
    112. Induction of catalase, alpha, and microsomal glutathione S‐transferase in CYP2E1 overexpressing HepG2 cells and protection against short‐term oxidative stress
    113. Tissue-specific expression and methylation of the human CYP2E1 gene
    114. Evaluation of caffeine as a test drug for CYP1A2, NAT2 and CYP2E1 phenotyping in man by in vivo versus in vitro correlations.
    115. Induction and recovery time course of rat brain CYP2E1 after nicotine treatment
    116. Histone modification-mediated CYP2E1 gene expression and apoptosis of HepG2 cells
    117. Genetic variations of NAT2 and CYP2E1 and isoniazid hepatotoxicity in a diverse population
    118. Association between CYP2E1 genetic polymorphisms and lung cancer risk: a meta-analysis
    119. Expression, catalytic activity, and inducibility of cytochrome P450 2E1 (CYP2E1) in the rat central nervous system
    120. Genetic polymorphisms in GSTM1,-P1,-T1, and CYP2E1 and the risk of adult brain tumors
    121. The human CYP2E1 gene and lung cancer: DraI and RsaI restriction fragment length polymorphisms in a Finish study population
    122. Taurine protects acetaminophen-induced oxidative damage in mice kidney through APAP urinary excretion and CYP2E1 inactivation
    123. Synergistic toxicity of iron and arachidonic acid in HepG2 cells overexpressing CYP2E1
    124. Post-transcriptional regulation of rat CYP2E1 expression: role of CYP2E1 mRNA untranslated regions in control of translational efficiency and message stability
    125. CYP2E1* 1D regulatory polymorphism: association with alcohol and nicotine dependence
    126. Ethanol‐mediated carcinogenesis in the human esophagus implicates CYP2E1 induction and the generation of carcinogenic DNA‐lesions
    127. Role of alcohol and genetic polymorphisms of CYP2E1 and ALDH2 in breast cancer development
    128. Identification of novel toxicity-associated metabolites by metabolomics and mass isotopomer analysis of acetaminophen metabolism in wild-type and CYP2E1 …
    129. Bimodal targeting of microsomal CYP2E1 to mitochondria through activation of an N-terminal chimeric signal by cAMP-mediated phosphorylation
    130. Allele and genotype frequencies of polymorphic cytochromes P450 (CYP2C9, CYP2C19, CYP2E1) and dihydropyrimidine dehydrogenase (DPYD) in the Egyptian …
    131. Role of CYP2D6, CYP1A1, CYP2E1, GSTT1, and GSTM1 genes in the susceptibility to acute leukemias
    132. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress
    133. Lipopolysaccharide-induced liver injury in rats treated with the CYP2E1 inducer pyrazole
    134. Elucidation of CYP2E1 5′ regulatory RsaI/Pstl allelic variants and their role in risk for oral cancer
    135. The role of CYP2E1 and 2B1 in metabolic activation of benzene derivatives
    136. The investigation into CYP2E1 in relation to the level of response to alcohol through a combination of linkage and association analysis
    137. Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling
    138. Construction and assessment of models of CYP2E1: predictions of metabolism from docking, molecular dynamics, and density functional theoretical calculations
    139. Acetoacetate induces CYP2E1 protein and suppresses CYP2E1 mRNA in primary cultured rat hepatocytes
    140. The RsaI polymorphism of CYP2E1 and susceptibility to alcoholic liver disease in Caucasians: effect on age of presentation and dependence on alcohol …
    141. Effect of ethanol on cytochrome P450 2E1 (CYP2E1), lipid peroxidation, and serum protein adduct formation in relation to liver pathology pathogenesis
    142. Metabolism of benzene in human liver microsomes: individual variations in relation to CYP2E1 expression
    143. Phyllanthus urinaria extract attenuates acetaminophen induced hepatotoxicity: involvement of cytochrome P450 CYP2E1
    144. Constitutive and inducible expression of hepatic CYP2E1 in leptin-deficient ob/ob mice
    145. CYP2E1 and NQO1 genotypes, smoking and bladder cancer
    146. Study of polymorphisms in the CYP2E1 gene in patients with alcoholic pancreatitis
    147. The GST T1 and CYP2E1 genotypes are possible factors causing vinyl chloride induced abnormal liver function
    148. Role of the Liver-Enriched Transcription Factor HNF-1α in Expression of the CYP2E1 Gene
    149. Ontogeny of hepatic CYP1A2 and CYP2E1 expression in rat
    150. Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo
    151. Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice
    152. Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol‐induced oxidative DNA damage in rodent liver
    153. The effect of ethanol-induced CYP2E1 on proteasome activity: the role of 4-hydroxynonenal
    154. Regional and cellular distribution of CYP2E1 in monkey brain and its induction by chronic nicotine
    155. Association of genetic polymorphisms in CYP2E1, MPO, NQO1, GSTM1, and GSTT1 genes with benzene poisoning.
    156. Variation in induction of human placental CYP2E1: possible role in susceptibility to fetal alcohol syndrome?
    157. Genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 associated with head and neck cancer
    158. Rapid changes in cytochrome P4502E1 (CYP2E1) activity and other P450 isozymes following ethanol withdrawal in rats
    159. Risk assessment: toxicity from chemical exposure resulting from enhanced expression of CYP2E1
    160. … for the Expression of Recombinant Human Cytochrome P450s inEscherichia coliUsing Bacterial Signal Peptides: Expression of CYP3A4, CYP2A6, and CYP2E1
    161. Relationship between mRNA levels quantified by reverse transcription-competitive PCR and metabolic activity of CYP3A4 and CYP2E1 in human liver
    162. Genetic polymorphism analysis of cytochrome P4502E1 (CYP2E1) in Chinese Han populations from four different geographic areas of Mainland China
    163. Transgenic alfalfa plants co-expressing glutathione S-transferase (GST) and human CYP2E1 show enhanced resistance to mixed contaminates of heavy metals and …
    164. Characterization of cytochrome P4502E1 turnover in transfected HepG2 cells expressing human CYP2E1
    165. Polymorphism in cytochrome P450 CYP2D6, CYP1A1, CYP2E1 and glutathione S-transferase, GSTM1, GSTM3, GSTT1 and susceptibility to tobacco-related cancers …
    166. Construction of a CYP2E1-template system for prediction of the metabolism on both site and preference order
    167. Trade herbal products and induction of CYP2C19 and CYP2E1 in cultured human hepatocytes
    168. Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1
    169. CYP2E1 is preferentially expressed in Clara cells of murine lung: localization by in situ hybridization and immunohistochemical methods.
    170. NQO1, MPO, CYP2E1, GSTT1 and GSTM1 polymorphisms and biological effects of benzene exposure—a literature review
    171. Spectrophotometric Analysis of Human CYP2E1-Catalyzed p-Nitrophenol Hydroxylation
    172. An interaction between the cytochrome P450 probe substrates chlorzoxazone (CYP2E1) and midazolam (CYP3A)
    173. Heteromeric complex formation between CYP2E1 and CYP1A2: evidence for the involvement of electrostatic interactions
    174. CYP2E1 induced by ethanol causes oxidative stress, proteasome inhibition and cytokeratin aggresome (Mallory body-like) formation
    175. Pharmacokinetics of theophylline in diabetes mellitus rats: induction of CYP1A2 and CYP2E1 on 1, 3-dimethyluric acid formation
    176. Inhibition of CYP2E1 Reverses CD4+ T-Cell Alterations in Trichloroethylene-Treated MRL+/+ Mice
    177. Genetic polymorphisms of CYP2D6, CYP1A1 and CYP2E1 in the South-Amerindian population of Chile.
    178. Amelioration of oxidative stress by dandelion extract through CYP2E1 suppression against acute liver injury induced by carbon tetrachloride in sprague‐dawley rats
    179. CYP2E1-dependent hepatotoxicity and oxidative damage after ethanol administration in human primary hepatocytes
    180. St. John’s wort extract induces CYP3A and CYP2E1 in the Swiss Webster mouse
    181. Effect of antifungal drugs on cytochrome P450 (CYP) 1A2, CYP2D6, and CYP2E1 activities in human liver microsomes
    182. Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine
    183. Combined analysis of germline polymorphisms of p53, GSTM1, GSTT1, CYP1A1, and CYP2E1: relation to the incidence rate of cervical carcinoma
    184. Immunohistochemical demonstration of the expression of CYP2E1 in human breast tumour and non-tumour tissues
    185. Major tanshinones of Danshen (Salvia miltiorrhiza) exhibit different modes of inhibition on human CYP1A2, CYP2C9, CYP2E1 and CYP3A4 activities in vitro
    186. Genetic polymorphisms in cytochrome P450 (CYP) 1A1, CYP1A2, CYP2E1, glutathione S-transferase (GST) M1 and GSTT1 and susceptibility to prostate cancer in the …
    187. Modeling interchild differences in pharmacokinetics on the basis of subject-specific data on physiology and hepatic CYP2E1 levels: a case study with toluene
    188. A significantly joint effect between arsenic and occupational exposures and risk genotypes/diplotypes of CYP2E1, GSTO1 and GSTO2 on risk of urothelial carcinoma
    189. CYP2E1 regulation by benzene and other small organic chemicals in rat liver and peripheral lymphocytes
    190. Metabolic oxidation and toxification of N-methylformamide catalyzed by the cytochrome P450 isoenzyme CYP2E1.
    191. Differential Modulation of CYP2E1 Activity by CAMP-Dependent Protein Kinase upon Ser129Replacement
    192. Kinetic characterization of CYP2E1 inhibition in vivo and in vitro by the chloroethylenes
    193. Translational activation of ethanol-inducible cytochrome P450 (CYP2E1) by isoniazid
    194. Effects of occupation, lifestyle and genetic polymorphisms of CYP1A1, CYP2E1, GSTM1 and GSTT1 on urinary 1-hydroxypyrene and 2-naphthol concentrations
    195. Distribution and differential induction of CYP2E1 by ethanol and acetone in the mesocorticolimbic system of rat
    196. Identification and characterization of a mitochondrial targeting signal in rat cytochrome P450 2E1 (CYP2E1)
    197. Investigation of xenobiotics metabolism, genotoxicity, and carcinogenicity using CYP2E1-/-mice
    198. CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling
    199. Analysis of CYP2E1 polymorphism for the determination of genetic susceptibility to gastric cancer in Koreans
    200. Obesity-induced increase of CYP2E1 activity and its effect on disposition kinetics of chlorzoxazone in Zucker rats
    201. Lung cancer risk in relation to the CYP2E1 Rsa I genetic polymorphism among African-Americans and Caucasians in Los Angeles County.
    202. Polymorphism in CYP1A1 and CYP2E1 genes and susceptibility to leukoplakia in Indian tobacco users
    203. Early Alcoholic Liver Injury: Formation of Protein Adducts with Acetaldehyde and Lipid Peroxidation Products, and Expression of CYP2E1 AND CYP3A
    204. Frequencies of genotypes and alleles of the functional SNPs in CYP2C19 and CYP2E1 in mainland Chinese Kazakh, Uygur and Han populations
    205. CYP1A1 CYP2E1 and GSTM1 polymorphisms are not associated with susceptibility to squamous‐cell carcinoma of the esophagus
    206. Influence of CYP1A1, CYP2E1, GSTM3 and NAT2 genetic polymorphisms in oral cancer susceptibility: results from a case-control study in Rio de Janeiro
    207. Effects of cytochrome P450 (CYP) 2A6 gene deletion and CYP2E1 genotypes on gastric adenocarcinoma
    208. Involvement of CYP2E1 as a low-affinity enzyme in phenacetin O-deethylation in human liver microsomes
    209. Adenovirus-mediated expression of CYP2E1 produces liver toxicity in mice
    210. Metabolic activation of N-alkylnitrosamines in genetically engineered Salmonella typhimurium expressing CYP2E1 or CYP2A6 together with human NADPH …
    211. Combined metadoxine and garlic oil treatment efficaciously abrogates alcoholic steatosis and CYP2E1 induction in rat liver with restoration of AMPK activity
    212. A Novel Polymorphism rs1329149 of CYP2E1 and a Known Polymorphism rs671 of ALDH2 of Alcohol Metabolizing Enzymes Are Associated with Colorectal Cancer …
    213. Association of CYP2E1 and NAT2 gene polymorphisms with chronic obstructive pulmonary disease
    214. CYP2A6 and CYP2E1 polymorphisms in a Brazilian population living in Rio de Janeiro
    215. Microsomal ethanol oxidizing system: transcriptional and posttranscriptional regulation of cytochrome P450, CYP2E1.
    216. Mitochondrial dysfunction by γ-irradiation accompanies the induction of cytochrome P450 2E1 (CYP2E1) in rat liver
    217. Role of CYP2E1 genotypes in susceptibility to colorectal cancer in the Kashmiri population
    218. Acetaldehyde generating enzyme systems: roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes
    219. Inactivation of stress protein p8 increases murine carbon tetrachloride hepatotoxicity via preserved CYP2E1 activity
    220. Lycopene attenuates alcoholic apoptosis in HepG2 cells expressing CYP2E1
    221. CYP2E1 degradation by in vitro reconstituted systems: role of the molecular chaperone hsp90
    222. CYP1A1, CYP2D6, CYP2E1, NAT2, GSTM1 and GSTT1 polymorphisms or their combinations are associated with the increased risk of the laryngeal squamous cell …
    223. Induction of nicotine-metabolizing CYP2B1 by ethanol and ethanol-metabolizing CYP2E1 by nicotine: summary and implications
    224. Expression of CYP2E1 in human nasopharynx and its metabolic effect in vitro
    225. Role of p38 MAPK in CYP2E1-dependent arachidonic acid toxicity
    226. Genetic Polymorphisms of ADH1C and CYP2E1 and Risk of Oral Squamous Cell Carcinoma
    227. Ethnic susceptibility to lung cancer: differences in CYP2E1, CYP1A1 and GSTM1 genetic polymorphisms between French Caucasian and Chilean populations
    228. CYP2E1 expression in human lymphocytes from various ethnic populations
    229. Association between CYP2E1 polymorphisms and susceptibility to prostate cancer
    230. CYP2E1 potentiation of LPS and TNFα-induced hepatotoxicity by mechanisms involving enhanced oxidative and nitrosative stress, activation of MAP kinases …
    231. CYP2E1-dependent benzene toxicity: the role of extrahepatic benzene metabolism
    232. The effects of alcohol and diallyl sulphide on CYP2E1 activity in humans: a phenotyping study using chlorzoxazone
    233. Distribution of ADH1B, ALDH2, CYP2E1∗ 6, and CYP2E1∗ 7B genotypes in Turkish population
    234. The effect of CYP2E1-dependent oxidant stress on activity of proteasomes in HepG2 cells
    235. Genetic polymorphism of CYP2E1, ADH2, and ALDH2 in Mexican-Americans
    236. Effect of ALDH2 and CYP2E1 Gene Polymorphisms on Drinking Behavior and Alcoholic Liver Disease in Japanese Male Workers
    237. Tandem Repeat Polymorphism of the CYP2E1 Gene: An Association Study With Esophageal Cancer and Lung Cancer
    238. The pig CYP2E1 promoter is activated by COUP-TF1 and HNF-1 and is inhibited by androstenone
    239. CYP1A2* 1C, CYP2E1* 5B, and GSTM1 polymorphisms are predictors of risk and poor outcome in head and neck squamous cell carcinoma patients
    240. Polymorphisms in glutathione S‐transferases GSTM1, GSTT1 and GSTP1 and cytochromes P450 CYP2E1 and CYP1A1 and susceptibility to cirrhosis or …
    241. DNA damage and cytotoxicity in pancreatic β-cells expressing human CYP2E1
    242. Cytochrome P4502E1 (CYP2E1) expression in peripheral blood lymphocytes: evaluation in hepatitis C and diabetes
    243. Molecular modelling of human CYP2E1 by homology with the CYP102 haemoprotein domain: investigation of the interactions of substrates and inhibitors within the …
    244. Relationship in healthy subjects between CYP2E1 genetic polymorphisms and the 6-hydroxyIation of chlorzoxazone: a putative measure of CYP2E1 activity
    245. Pharmacokinetics of chlorzoxazone in rats with diabetes: induction of CYP2E1 on 6-hydroxychlorzoxazone formation
    246. Significance of genetic polymorphisms at multiple loci of CYP2E1 in the risk of development of childhood acute lymphoblastic leukemia
    247. The effect of isoniazid on CYP2E1-and CYP4A-mediated hydroxylation of arachidonic acid in the rat liver and kidney
    248. Immunohistochemical study of CYP2E1 in hepatocellular carcinoma carcinogenesis: examination with newly prepared anti-human CYP2E1 antibody
    249. Human hepatocytes are protected from ethanol-induced cytotoxicity by DADS via CYP2E1 inhibition
    250. Genetic polymorphism of the CYP1A1, CYP2E1, GSTM1 and GSTT1 genes and lung cancer susceptibility in a north Indian population
    251. Cytochrome CYP2E1 phenotyping and genotyping in the evaluation of health risks from exposure to polluted environments
    252. Growth retardation of fetal rats exposed to nicotine in utero: Possible involvement of CYP1A1, CYP2E1, and P‐glycoprotein
    253. Association of GSTM1, CYP1A1 and CYP2E1 genetic polymorphisms with susceptibility to lung adenocarcinoma: A case‐control study in Chinese population
    254. Induction of hepatic CYP2E1 by a subtoxic dose of acetaminophen in rats: increase in dichloromethane metabolism and carboxyhemoglobin elevation
    255. CYP2E1 Rsa I polymorphism impacts on risk of colorectal cancer association with smoking and alcohol drinking
    256. The impact of CYP2E1 genetic variability on risk assessment of VOC mixtures
    257. Protective effects of goldenseal (Hydrastis canadensis L.) on acetaminophen-induced hepatotoxicity through inhibition of CYP2E1 in rats
    258. Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism
    259. CYP2A6/2A7 and CYP2E1 expression in human oesophageal mucosa: regional and inter-individual variation in expression and relevance to nitrosamine metabolism
    260. Global Analysis of Protein− Protein Interactions Reveals Multiple CYP2E1− Reductase Complexes
    261. Differential role of CYP2E1 binders and isoniazid on CYP2E1 protein modification in NADPH-dependent microsomal oxidative reactions: free radical scavenging …
    262. Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity
    263. Polymorphisms of CYP1a1, CYP2E1, GSTM1, GSTT1, and TP53 genes in Amerindians
    264. CYP1A1, CYP2E1, GSTM1, GSTT1, EPHX1 exons 3 and 4, and NAT2 polymorphisms, smoking, consumption of alcohol and fruit and vegetables and risk of head and …
    265. CYP2E1 Rsa I/Pst I polymorphism is associated with lung cancer risk among Asians
    266. The role of CYP2A and CYP2E1 in the metabolism of 3-methylindole in primary cultured porcine hepatocytes
    267. Homology modelling of human CYP2E1 based on the CYP2C5 crystal structure: investigation of enzyme–substrate and enzyme–inhibitor interactions
    268. Studies on interindividual variations of CYP2E1 using chlorzoxazone as an in vivo probe
    269. A Case–control and a family-based association study revealing an association between CYP2E1 polymorphisms and nasopharyngeal carcinoma risk …
    270. Functional polymorphism in porcine CYP2E1 gene: Its association with skatole levels
    271. Identification of CYP2E1 in marmoset monkey
    272. Effects of diabetes on rabbit kidney and lung CYP2E1 and CYP2B4 expression and drug metabolism and potentiation of carcinogenic activity of N …
    273. Does CYP2E1 play a major role in the aggravation of isoniazid toxicity by rifampicin in human hepatocytes?
    274. Relationship between genetic polymorphisms of metabolizing enzymes CYP2E1, GSTM1 and Kazakh’s esophageal squamous cell cancer in Xinjiang, China
    275. ADH2 and CYP2E1 genetic polymorphisms: risk factors for alcohol-related birth defects
    276. Renal and hepatic accumulation of cadmium and lead in the expression of CYP4F2 and CYP2E1
    277. Ageing is associated with increased expression but decreased activity of CYP2E1 in male Wistar rats
    278. Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity
    279. Porcine CYP2A19, CYP2E1 and CYP1A2 forms are responsible for skatole biotransformation in the reconstituted system
    280. Effect of cigarette smoke on hepatic and pulmonary cytochromes P450 in mouse: evidence for CYP2E1 induction in lung
    281. CYP2E1 and ALDH2 genotypes and alcohol dependence in Japanese
    282. Effect of fasting and obesity in humans on the 6‐hydroxylation of chlorzoxazone: a putative probe of CYP2E1 activity
    283. Benzene-induced genotoxicity in mice in vivo detected by the alkaline comet assay: reduction by CYP2E1 inhibition
    284. Adverse Birth Outcomes Associated with Maternal Smoking and Polymorphisms in the N-Nitrosamine-Metabolizing Enzyme Genes NQO1 and CYP2E1
    285. NADPH-dependent microsomal electron transfer increases degradation of CYP2E1 by the proteasome complex: role of reactive oxygen species
    286. Hypomethylation and hypoexpression of human CYP2E1 gene in lung tumors
    287. GSTT1 and CYP2E1 polymorphisms and trihalomethanes in drinking water: effect on childhood leukemia.
    288. Inhibition of CYP2E1 with natural agents may be a feasible strategy for minimizing the hepatotoxicity of ethanol
    289. A High Throughput Screening Assay to Screen for CYP2E1 Metabolism and Inhibition Using a Fluorogenic Vivid® P450 Substrate
    290. Ethanol and arachidonic acid produce toxicity in hepatocytes from pyrazole-treated rats with high levels of CYP2E1
    291. GSTT1, GSTM1 and CYP2E1 genetic polymorphisms in gastric cancer and chronic gastritis in a Brazilian population
    292. A temporal study on the histopathological, biochemical and molecular responses of CCl4-induced hepatotoxicity in CYP2E1-null mice
    293. Effects of Ganoderma lucidum polysaccharide on CYP2E1, CYP1A2 and CYP3A activities in BCG-immune hepatic injury in rats
    294. Expression of CYP2E1 in Human Lung and Kidney during Development and in Full‐Term Placenta: A Differential Methylation of the Gene is Involved in the …
    295. Comparative metabolism and disposition of trichloroethylene in CYP2E1–/–and wild-type mice
    296. Inhibition of cytochrome P450 enzymes participating in p-nitrophenol hydroxylation by drugs known as CYP2E1 inhibitors
    297. Chlorzoxazone as a single sample probe of hepatic CYP2E1 activity in humans
    298. Kupffer cell inactivation alleviates ethanol-induced steatosis and CYP2E1 induction but not inflammatory responses in rat liver
    299. Protective effects of emodin and chrysophanol isolated from marine fungus Aspergillus sp. on ethanol-induced toxicity in HepG2/CYP2E1 cells
    300. Association of combined CYP2E1 gene polymorphism with the risk for esophageal squamous cell carcinoma in Huai’an population, China
    301. Covalent immobilization of recombinant human cytochrome CYP2E1 and glucose-6-phosphate dehydrogenase in alumina membrane for drug screening applications
    302. Promoter function and the role of cytokines in the transcriptional regulation of rabbit CYP2E1 and CYP2E2
    303. Differential effects of diabetes on CYP2E1 and CYP2B4 proteins and associated drug metabolizing enzyme activities in rabbit liver
    304. … exposure to styrene: modulation of cytogenetic damage and levels of urinary metabolites of styrene by polymorphisms in genes CYP2E1, EPHX1, GSTM1, GSTT1 …
    305. Relationship between alcoholism and CYP2E1 C/D polymorphism
    306. Polymorphism of metabolizing genes and lung cancer histology: prevalence of CYP2E1 in adenocarcinoma
    307. Differential effects of dietary fatty acids on the regulation of CYP2E1 and protein kinase C in human hepatoma HepG2 cells
    308. Cytochrome P4502E1 (CYP2E1) genetic polymorphism in a case-control study of gastric cancer and liver disease.
    309. Lymphocyte cytochrome P450-CYP2E1 expression in human IDDM subjects
    310. Role of calcium and calcium-activated proteases in CYP2E1-dependent toxicity in HEPG2 cells
    311. Oxidative stress potentiated by diallylsulfide, a selective CYP2E1 inhibitor, in isoniazid toxic effect on rat primary hepatocytes
    312. Relationship between genetic polymorphisms of drug-metabolizing enzymes (CYP1A1, CYP2E1, GSTM1, and NAT2), drinking habits, histological subtypes, and p53 …
    313. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin
    314. Role of intracellular calcium and phospholipase A2 in arachidonic acid-induced toxicity in liver cells overexpressing CYP2E1
    315. Helicobacter pylori infection, but not genetic polymorphism of CYP2E1, is highly prevalent in gastric cancer patients younger than 40 years
    316. Role of CYP2E1 immunoglobulin G4 subclass antibodies and complement in pathogenesis of idiosyncratic drug-induced hepatitis
    317. A negative cooperativity mechanism of human CYP2E1 inferred from molecular dynamics simulations and free energy calculations
    318. Hormone controlled phosphorylation and degradation of CYP2B1 and CYP2E1 in isolated rat hepatocytes
    319. Effects of the ADH3, CYP2E1, and GSTP1 genetic polymorphisms on their expressions in Caucasian lung tissue
    320. Genetic polymorphism of the CYP2E1 gene and susceptibility to Parkinson’s disease in Taiwanese
    321. Transcription factor Nrf2 protects HepG2 cells against CYP2E1 plus arachidonic acid-dependent toxicity
    322. Differential in vivo effects of α‐naphthoflavone and β‐naphthoflavone on CYP1A1 and CYP2E1 in rat liver, lung, heart, and kidney
    323. cDNA sequence, deduced amino acid sequence, predicted gene structure and chemical regulation of mouse CYP2E1
    324. … and CYP2E1 and N‐terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae − role of protein kinase A in the mitochondrial targeting of CYP2E1
    325. CYP2E1 PstI/RsaI polymorphism and colorectal cancer risk: a meta-analysis
    326. Lipopolysaccharide induces CYP2E1 in astrocytes through MAP kinase kinase-3 and C/EBPβ and-δ
    327. Inhibition of urethane-induced genotoxicity and cell proliferation in CYP2E1-null mice
    328. Depletion of cytosolic or mitochondrial thioredoxin increases CYP2E1-induced oxidative stress via an ASK-1–JNK1 pathway in HepG2 cells
    329. Theoretical study of the mechanism of acetaldehyde hydroxylation by compound I of CYP2E1
    330. Molecular modelling of CYP2E1 enzymes from rat, mouse and man: an explanation for species differences in butadiene metabolism and potential carcinogenicity, and …
    331. The molecular mechanism regulating 24‐hour rhythm of CYP2E1 expression in the mouse liver
    332. Ethanol‐related cytotoxicity catalyzed by CYP2E1‐dependent generation of reactive oxygen intermediates in transduced HepG2 cells
    333. Validation of the (ω-l)-hydroxylation of lauric acid as an in vitro substrate probe for human liver CYP2E1
    334. The ADH3* 2 and CYP2E1 c2 alleles increase the risk of alcoholism in Mexican American men
    335. Interindividual variability of chlorzoxazone 6‐hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
    336. Impact of CYP2E1 genotype in renal cell and urothelial cancer patients
    337. Docosahexaenoic acid induces apoptosis in CYP2E1-containing HepG2 cells by activating the c-Jun N-terminal protein kinase related mitochondrial damage
    338. Decreased protein and mRNA expression of ER stress proteins GRP78 and GRP94 in HepG2 cells over-expressing CYP2E1
    339. Role of CYP2E1 activity in endoplasmic reticulum ubiquitination, proteasome association, and the unfolded protein response
    340. Sodium salicylate increases CYP2E1 levels and enhances arachidonic acid toxicity in HepG2 cells and cultured rat hepatocytes
    341. Distribution of cytochrome CYP2E1 in murine liver after ethanol and acetone administration
    342. Contribution of CYP2E1 to N-methyl-2-pyrrolidone metabolism
    343. Induction and regulation of CYP2E1 in murine liver after acute and chronic acetone administration.
    344. Phenobarbital induces monkey brain CYP2E1 protein but not hepatic CYP2E1, in vitro or in vivo chlorzoxazone metabolism
    345. Ethanol-induced oxidative DNA damage and CYP2E1 expression in liver tissue of Aldh2 knockout mice
    346. Modification of CYP2E1 and CYP3A4 activities in haemoglobin E-beta thalassemia patients
    347. Changes of CYP2E1 activity in diabetic rat model
    348. Use of molecular simulation for mapping conformational CYP2E1 epitopes
    349. Ethanol enhanced the genotoxicity of acrylamide in human, metabolically competent HepG2 cells by CYP2E1 induction and glutathione depletion
    350. Global patterns of variation in allele and haplotype frequencies and linkage disequilibrium across the CYP2E1 gene
    351. The cytochrome P-450 isoenzyme CYP2E1 in the biological processing of industrial chemicals: consequences for occupational and environmental medicine
    352. Differential metabolism of acrylonitrile to cyanide is responsible for the greater sensitivity of male vs female mice: role of CYP2E1 and epoxide hydrolases
    353. CYP2E1 expression in bone marrow and its intra-and interspecies variability: approaches for a more reliable extrapolation from one species to another in the risk …
    354. Role of CYP2E1 and saturation kinetics in the bioactivation of thioacetamide: Effects of diet restriction and phenobarbital
    355. Stable expression of human CYP2E1 in Chinese hamster cells: high sensitivity to N, N-dimethylnitrosamine in cytotoxicity testing
    356. Immunological detection of CYP2E1 in fresh rat lymphocytes and its pretranslational induction by fasting
    357. The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C
    358. Comparison of genetic polymorphisms of CYP2E1, ADH2, and ALDH2 genes involved in alcohol metabolism in Koreans and four other ethnic groups
    359. Identification of inhibitory component in cinnamon—o-methoxycinnamaldehyde inhibits cyp1a2 and CYP2E1—
    360. Hepatic and pulmonary microsomal benzene metabolism in CYP2E1 knockout mice
    361. … in urea in conjunction with L-arginine metabolism in the liver leads to induction of cytochrome P450 2E1 (CYP2E1): The role of urea in CYP2E1 induction by acute …
    362. Effect of chronic disulfiram administration on the activities of CYP1A2, CYP2C19, CYP2D6, CYP2E1, and N‐acetyltransferase in healthy human subjects
    363. Detection of auto-antibodies against cytochrome P4502E1 (CYP2E1) in chronic hepatitis C
    364. CYP2E1-catalyzed oxidation contributes to the sperm toxicity of 1-bromopropane in mice
    365. Protective effects of loquat (Eriobotrya japonica) leaves against ethanol-induced toxicity in HepG2 cells transfected with CYP2E1
    366. Transfected HepG2 cells for evaluation of catechin effects on alcohol-induced CYP2E1 cytotoxicity
    367. Safrole-DNA adducts in human peripheral blood—an association with areca quid chewing and CYP2E1 polymorphisms
    368. Increased bioaccumulation of urethane in CYP2E1-/-versus CYP2E1+/+ mice
    369. Spin trapping agents (Tempol and POBN) protect HepG2 cells overexpressing CYP2E1 against arachidonic acid toxicity
    370. Age-related changes in the protein and mRNA levels of CYP2E1 and CYP3A isoforms as well as in their hepatic activities in Wistar rats. What role for oxidative stress?
    371. Functional CYP2E1 is required for substantial in vivo formation of 2, 5-hexanedione from n-hexane in the mouse
    372. Metabolism of ethyl carbamate by pulmonary cytochrome P450 and carboxylesterase isozymes: involvement of CYP2E1 and hydrolase A
    373. Genetic Repeat Polymorphism in the Regulating Region of CYP2E1: Frequency and Relationship With Enzymatic Activity in Alcoholics
    374. … by allyl sulfides and phenethyl isothiocyanate of methyl-n-pentylnitrosamine depentylation by rat esophageal microsomes, human and rat CYP2E1, and Rat CYP2A3
    375. Effects of ALDH2, CYP1A1, and CYP2E1 genetic polymorphisms and smoking and drinking habits on toluene metabolism in humans
    376. Therapeutic hypothermia-induced pharmacokinetic alterations on CYP2E1 chlorzoxazone-mediated metabolism in a cardiac arrest rat model
    377. Investigation of bioactivation and toxicity of styrene in CYP2E1 transgenic cells
    378. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co‐expressing HCV core protein and CYP2E1
    379. Acute ethanol pretreatment increases FAS-mediated liver injury in mice: role of oxidative stress and CYP2E1-dependent and-independent pathways
    380. DNA repair XRCC1 Arg399Gln polymorphism alone, and in combination with CYP2E1 polymorphisms significantly contribute to the risk of development of childhood …
    381. Do Endogenous Volatile Organic Chemicals Measured in Breath Reflect and Maintain CYP2E1 Levelsin Vivo?
    382. XRCC1 and CYP2E1 Polymorphisms as Susceptibility Factors of Plasma Mutant p53 Protein and Anti-p53 Antibody Expression in Vinyl Chloride …
    383. Evidence of association of the CYP2E1 genetic polymorphism with micronuclei frequency in human peripheral blood
    384. Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation)
    385. CYP2E1 mRNA expression, genetic polymorphisms in peripheral blood lymphocytes and liver abnormalities in Chinese VCM-exposed workers
    386. Role of CYP1A2 and CYP2E1 in the pentoxifylline ciprofloxacin drug interaction
    387. Comparison of the susceptibility of wild-type and CYP2E1 knockout mice to the hepatotoxic and pneumotoxic effects of styrene and styrene oxide
    388. High inducibility of mouse renal CYP2E1 gene by tobacco smoke and its possible effect on DNA single strand breaks
    389. Effect of the CYP2E1 genotype on vinyl chloride monomer-induced liver fibrosis among polyvinyl chloride workers
    390. Gene–environmental interactions between alcohol-drinking behavior and ALDH2 and CYP2E1 polymorphisms and their impact on micronuclei frequency in human …
    391. Duration of cytochrome P-450 2E1 (CYP2E1) inhibition and estimation of functional CYP2E1 enzyme half-life after single-dose disulfiram administration in humans
    392. Induction of CYP2E1 activity in liver transplant patients as measured by chlorzoxazone 6‐hydroxylation
    393. Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality
    394. Pulmonary bioactivation of trichloroethylene to chloral hydrate: relative contributions of CYP2E1, CYP2F, and CYP2B1
    395. The 2006 bernard B. Brodie award lecture: CYP2E1
    396. Differential induction of ethanol-metabolizing CYP2E1 and nicotine-metabolizing CYP2B1/2 in rat liver by chronic nicotine treatment and voluntary ethanol intake
    397. Effects of genetic polymorphisms of CYP1A1, CYP2E1, GSTM1, and GSTT1 on the urinary levels of 1-hydroxypyrene and 2-naphthol in aircraft maintenance workers
    398. Genetic polymorphisms of CYP2E1 and GSTM1 in a Thai population
    399. DLPC attenuates alcohol-induced cytotoxicity in HepG2 cells expressing CYP2E1
    400. Role of polymorphic CYP2E1 and CYP2D6 genes in NNK-induced chromosome aberrations in cultured human lymphocytes
    401. A comparison of substrate dynamics in human CYP2E1 and CYP2A6
    402. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice
    403. Expression of CYP2E1 by human monocyte‐derived macrophages
    404. CYP2E1 polymorphisms and gene–environment interactions in the risk of upper aerodigestive tract cancers among Indians
    405. NAT2, CYP2C9, CYP2C19, and CYP2E1 genetic polymorphisms in anti-TB drug-induced maculopapular eruption
    406. Role of CYP2E1 in the pathogenesis of alcoholic liver disease: modifications by cAMP and ubiquitin-proteasome pathway
    407. Spectrophotometric analysis of human CYP2E1-catalyzed p-nitrophenol hydroxylation
    408. Cervical cancer and CYP2E1 polymorphisms: implications for molecular epidemiology
    409. Inactivation of hepatic CYP2E1 by an epoxide of diallyl sulfone
    410. Insertion polymorphism of CYP2E1 and urinary N-methylformamide after N, N-dimethylformamide exposure in Japanese workers
    411. Effect of exposure to benzo [a] pyrene on SODs, CYP1A1/1A2-and CYP2E1 immunopositive proteins in the blood clam Scapharca inaequivalvis
    412. Ethanol-mediated transplacental induction of CYP2E1 in fetal rat liver
    413. Breaking self-tolerance toward cytochrome P4502E1 (CYP2E1) in chronic hepatitis C: possible role for molecular mimicry
    414. Cytochrome P450 2E1 (CYP2E1)-dependent production of a 37-kDa acetaldehyde–protein adduct in the rat liver
    415. Ethanol intake and ethanol-induced locomotion and locomotor sensitization in CYP2E1 knockout mice
    416. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratios
    417. Genotype and allele frequencies of polymorphic cytochromes P450 CYP1A2 and CYP2E1 in Mexicans
    418. CYP1A1, CYP2E1, GSTM1, GSTT1, GSTP1, and TP53 polymorphisms: do they indicate susceptibility to chronic obstructive pulmonary disease and non-small-cell …
    419. Effects of dietary fat composition on activities of the microsomal ethanol oxidizing system and ethanol‐inducible cytochrome P450 (CYP2E1) in the liver of rats …
    420. Use of the CYP2E1 genotype and phenotype for the biological monitoring of occupational exposure to styrene
    421. In vivo and in vitro characterization of chlorzoxazone metabolism and hepatic CYP2E1 levels in African Green monkeys: induction by chronic nicotine treatment
    422. Proteasome inhibition potentiates CYP2E1‐mediated toxicity in HepG2 cells
    423. Effect of CYP2E1 gene deletion in mice on expression of microsomal epoxide hydrolase in response to VCD exposure
    424. Adenovirus-mediated expression of Cu/Zn-or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity
    425. CYP2E1 G1532C, NQO1 Pro187Ser, and CYP1B1 Val432Leu polymorphisms are not associated with risk of squamous cell carcinoma of the head and neck
    426. CYP2E1 active site residues in substrate recognition sequence 5 identified by photoaffinity labeling and homology modeling
    427. Malotilate, a hepatoprotectant, suppresses CYP2E1 expression in rats
    428. Role of mouse CYP2E1 in the O-hydroxylation of p-nitrophenol: comparison of activities in hepatic microsomes from CYP2E1 (-/-) and wild-type mice
    429. Pulsatile blood alcohol and CYP2E1 induction during chronic alcohol infusions in rats
    430. … dehydrogenase 2, cytochrome p450 2E1 for liver cancer risk in HCV antibody-positive japanese patients and the variations of CYP2E1 mRNA expression levels in the …
    431. Use of CYP2E1‐transfected human liver cell lines in elucidating the actions of ethanol
    432. In vivo CYP2E1 phenotyping as a new potential biomarker of occupational and experimental exposure to benzene
    433. Induction of DNA strand breaks and oxidative stress in HeLa cells by ethanol is dependent on CYP2E1 expression
    434. Genetic polymorphisms of the CYP2E1 gene do not contribute to oral cancer susceptibility in south Indians
    435. Phenotype distribution and gender-related differences of CYP2E1 activity in a Chinese population
    436. Trimethadione metabolism by human liver cytochrome P450: evidence for the involvement of CYP2E1
    437. Influence of genetic admixture on polymorphisms of drug‐metabolizing enzymes: Analyses of mutations on NAT2 and CYP2E1 genes in a mixed Hispanic …
    438. Role of the proteasome complex in degradation of human CYP2E1 in transfected HepG2 cells
    439. Association Studies of Polymorphisms of CYP2E1 Gene in Alcoholics with Cirrhosis, Antisocial Personality, and Normal Controls
    440. Transcriptional and posttranscriptional regulation of CYP2E1, an N-nitrosodimethylamine demethylase.
    441. Association of CYP2E1, GST and mEH genetic polymorphisms with urinary acrylamide metabolites in workers exposed to acrylamide
    442. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity
    443. Chronic ethanol feeding potentiates Fas Jo2-induced hepatotoxicity: Role of CYP2E1 and TNF-α and activation of JNK and P38 MAP kinase
    444. Role of CYP2E1 in deramciclane metabolism
    445. S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury
    446. The influence of genetic polymorphism of CYP2E1 on the development of alcohol liver cirrhosis
    447. p53 mutation spectrum in relation to GSTM1, CYP1A1 and CYP2E1 in surgically treated patients with non-small cell lung cancer.
    448. Evidence for a tissue-specific induction of cutaneous CYP2E1 by dexamethasone
    449. Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes
    450. Genetic Polymorphisms of CYP2E1 and Risk of Colorectal Adenomas in the Self Defense Forces Health Study
    451. CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls
    452. The effect of lycopene on the total cytochrome P450, CYP1A2 and CYP2E1
    453. Chlorzoxazone metabolism by winter flounder liver microsomes: evidence for existence of a CYP2E1-like isoform in teleosts
    454. Role of CYP2E1 in the mouse model of MPTP toxicity
    455. Genetic polymorphism of CYP2E1 and digestive tract alcohol damage among Polish individuals
    456. CYP2E1 genotyping in renal cell/urothelial cancer patients in comparison with control populations.
    457. Genetic polymorphisms of CYP2E1, GSTT1, GSTP1, GSTM1, ALDH2, and ODC and the risk of advanced precancerous gastric lesions in a Chinese population
    458. Transgenic plants of Petunia hybrida harboring the CYP2E1 gene efficiently remove benzene and toluene pollutants and improve resistance to formaldehyde
    459. Induction of CYP2B and CYP2E1 in precision-cut rat liver slices cultured in defined medium
    460. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-κB …
    461. Mammalian cytochrome CYP2E1 triggered differential gene regulation in response to trichloroethylene (TCE) in a transgenic poplar
    462. CYP2E1 polymorphism, cigarette smoking, p53 expression, and survival in non-small cell lung cancer: a long term follow-up study
    463. Short-term treatment with alcohols causes hepatic steatosis and enhances acetaminophen hepatotoxicity in CYP2E1 (-/-) mice
    464. Phosphorylation of cytochrome P4502E1 (CYP2E1) by calmodulin dependent protein kinase protein kinase C and cAMP dependent protein kinase
    465. PI3K inhibitors reverse the suppressive actions of insulin on CYP2E1 expression by activating stress-response pathways in primary rat hepatocytes
    466. In vitro metabolism of styrene to styrene oxide in liver and lung of CYP2E1 knockout mice
    467. Dietary lipids affect human ethanol-inducible CYP2E1 gene expression in vivo in mononuclear cells
    468. Independent and combined effects of ethanol self-administration and nicotine treatment on hepatic CYP2E1 in African green monkeys
    469. … of human prenatal biosynthesis of all-trans-retinoic acid by ethanol, ethanol metabolites, and products of lipid peroxidation reactions: a possible role for CYP2E1
    470. Gene Structure and Multiple Regulations of the Ethanol-Inducible Cytochrome P45O2E1 (CYP2E1) Subfamily
    471. Role of phospholipase A2 activation and calcium in CYP2E1-dependent toxicity in HepG2 cells
    472. Panax vietnamensis protects mice against carbon tetrachloride-induced hepatotoxicity without any modification of CYP2E1 gene expression
    473. Study on the association between genetic polymorphism of CYP2E1, GSTM1 and susceptibility of lung cancer
    474. A multiplex-PCR/RFLP procedure for simultaneous CYP2E1, mEH and GSTM1 genotyping
    475. Lycopene attenuates arachidonic acid toxicity in HepG2 cells overexpressing CYP2E1
    476. APOE and CYP2E1 polymorphisms, alcohol consumption, and Parkinson’s disease in a Japanese population
    477. Epoxide formation from diallyl sulfone is associated with CYP2E1 inactivation in murine and human lungs
    478. D2-receptor-linked signaling pathways regulate the expression of hepatic CYP2E1
    479. Metabolic activation of o-phenylphenol to a major cytotoxic metabolite, phenylhydroquinone: role of human CYP1A2 and rat CYP2C11/CYP2E1
    480. Expression and activity of CYP2E1 in circulating lymphocytes are not altered in diabetic individuals
    481. Modification effects of GSTM1, GSTT1 and CYP2E1 polymorphisms on associations between raw salted food and incomplete intestinal metaplasia in a high‐risk …
    482. Validation of 4-nitrophenol as an in vitro substrate probe for human liver CYP2E1 using cDNA expression and microsomal kinetic techniques
    483. Depression of glutathione content, elevation of CYP2E1-dependent activation, and the principal determinant of the fasting-mediated enhancement of 1, 3-dichloro-2 …
    484. Effects of acute renal failure induced by uranyl nitrate on the pharmacokinetics of intravenous theophylline in rats: the role of CYP2E1 induction in 1, 3‐dimethyluric …
    485. Effects of N-acetyltransferase 2 (NAT2), CYP2E1 and Glutathione-S-transferase (GST) genotypes on the serum concentrations of isoniazid and metabolites in …
    486. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells
    487. No significant expression of CYP2E1 in rat liver stellate cells
    488. CYP2E1 and clinical features in alcoholics
    489. Comparison of chlorzoxazone one-sample methods to estimate CYP2E1 activity in humans
    490. Acetaminophen alters microsomal ryanodine Ca2+ channel in HepG2 cells overexpressing CYP2E1
    491. No Association between Polymorphisms in CYP2E1, GSTM1, NAT1, NAT2 and the Risk of Gastric Adenocarcinoma in the European Prospective Investigation into …
    492. The effect of isoniazid containing regimen on CYP2E1 during antituberculosis therapy.
    493. A Haplotype Analysis of CYP2E1 Polymorphisms in Relation to Alcoholic Phenotypes in Mexican Americans
    494. A reaction network model for CYP2E1-mediated metabolism of toxicant mixtures
    495. Ca2+-dependent and independent mitochondrial damage in HepG2 cells that overexpress CYP2E1
    496. Cytochrome b5 reductase and cytochrome b5 support the CYP2E1-mediated activation of nitrosamines in a recombinant Ames test
    497. Overexpression of CYP2E1 enhances sensitivity of hepG2 cells to fas-mediated cytotoxicity
    498. INFLUENCE OF GENETIC ADMIXTURE ON POLYMORPHISMS OF ALCOHOL-METABOLIZING ENZYMES: ANALYSES OF MUTATIONS ON THE CYP2E1, ADH2, ADH3 AND …
    499. Liver nuclear and microsomal CYP2E1-mediated metabolism of xenobiotics in rats chronically drinking an alcohol-containing liquid diet
    500. Effect of CYP2E1 induction by ethanol on the immunotoxicity and genotoxicity of extended low-level benzene exposure
    501. Role of nitric oxide and nuclear factor-κB in the CYP2E1 potentiation of tumor necrosis factor α hepatotoxicity in mice
    502. Identification of sequences responsible for intracellular targeting and membrane binding of rat CYP2E1 in yeast
    503. Suppression of cytochrome P450 2E1 promoter activity by interferon-γ and loss of response due to the-71G> T nucleotide polymorphism of the CYP2E1* 7B allele
    504. Identification and functional analysis of a novel human CYP2E1 far upstream enhancer
    505. Rifampicin suppresses hepatic CYP2E1 expression and minimizes DNA injury caused by carbon tetrachloride in perivenular hepatocytes of mice
    506. Inhibition of CYP2E1 activity does not abolish pulsatile urine alcohol concentrations during chronic alcohol infusions
    507. Molecular cloning and sequence analysis of hamster CYP2E1
    508. Relationship between genetic polymorphism of CYP2E1 and ALDH2, and possible susceptibility to alcoholism
    509. … mechanism of Wu-Zi-Yan-Zong-Wan, a traditional Chinese herbal formula, against alcohol-induced oxidative damage in CYP2E1 cDNA-transfected HepG2 (E47) …
    510. … overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1
    511. Effects of steady-state lasofoxifene on CYP2D6-and CYP2E1-mediated metabolism
    512. [12] Chlorzoxazone: An in vitro and in vivo substrate probe for liver CYP2E1
    513. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene in murine lung: formation of reactive intermediates and glutathione conjugates
    514. Modulation of mouse P450 isoforms CYP1A2, CYP2B10, CYP2E1, and CYP3A by the environmental chemicals mirex, 2, 2-bis (p-chlorophenyl)-1, 1-dichloroethylene …
    515. Lack of cytochrome P450 2E1 (CYP2E1) induction in the rat liver by starvation without coprophagy
    516. Influence of GSTs, CYP2E1 and mEH polymorphisms on 1, 3-butadiene-induced micronucleus frequency in Chinese workers
    517. Influence of GSTT1, mEH, CYP2E1 and RAD51 polymorphisms on diepoxybutane-induced SCE frequency in cultured human lymphocytes
    518. Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system
    519. Striking LD50 variation associated with fluctuations of CYP2E1-positive cells in hepatic lobule during chronic CCl4 exposure in mice
    520. Expression of cytochrome P450 enzymes CYP1A1, CYP1B1, CYP2E1 and CYP4B1 in cultured transitional cells from specimens of the human urinary tract and from …
    521. Isozyme-selective metabolism of ethyl carbamate by cytochrome P450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes in murine liver microsomes
    522. … of the accumulation of acetaldehyde from ethanol in human prenatal cephalic tissues: evaluation of the relative contributions of CYP2E1, alcohol dehydrogenase, and …
    523. CYP2E1 and CYP3A1/2 gene expression is not associated with the ursodeoxycholate effect on ethanol-induced lipoperoxidation
    524. CYP2E1 inhibition enhances mallory body formation
    525. XRCC1, CYP2E1 and ALDH2 genetic polymorphisms and sister chromatid exchange frequency alterations amongst vinyl chloride monomer-exposed polyvinyl …
    526. Cytochrome b5 coexpression increases the CYP2E1-dependent mutagenicity of dialkylnitrosamines in methyltransferase-deficient strains of Salmonella typhimurium
    527. Effect of disulfiram‐mediated CYP2E1 inhibition on the disposition of vesnarinone
    528. Nitric oxide donors prevent while the nitric oxide synthase inhibitor L-NAME increases arachidonic acid plus CYP2E1-dependent toxicity
    529. CYP2E1 overexpression inhibits microsomal Ca2+-ATPase activity in HepG2 cells
    530. Induction of brain CYP2E1 changes the effects of ethanol on dopamine release in nucleus accumbens shell
    531. The role of phosphatidylinositol 3-kinase, Src kinase, and protein kinase A signaling pathways in insulin and glucagon regulation of CYP2E1 expression
    532. Voglibose potentiates the hepatotoxicity of carbon tetrachloride and acetaminophen by inducing CYP2E1 in rats
    533. Administration of the tris salt of α-tocopheryl hemisuccinate inactivates CYP2E1, enhances microsomal α-tocopherol levels and protects against carbon tetrachloride …
    534. Influence of selected inhibitors on the metabolism of the styrene metabolite 4-vinylphenol in wild-type and CYP2E1 knockout mice
    535. Lack of common mutation in the alfa-subunit of the mitochondrial trifunctional protein and the polymorphism of CYP2E1 in three Japanese women with acute fatty liver …
    536. Induction of CYP1A1 and CYP2E1 in rat liver by histamine: binding and kinetic studies
    537. Cytochrome P4502E1 (CYP2E1) Genetic Polymorphisms in a Lebanese Population: Frequency Distribution and Association with Morbid Diseases
    538. CYP1A1 and CYP2E1 polymorphism frequencies in a large Brazilian population
    539. THE EFFECTS OF THE ALDH2*1/2, CYP2E1 C1/C2 AND C/D GENOTYPES ON BLOOD ETHANOL ELIMINATION
    540. Noninvolvement of CYP2E1 in the (ω-1)-hydroxylation of fatty acids in rat kidney microsomes
    541. Effect of total alkaloids of Rubus alceaefolius poiron on gene expressions of CYP2E1 and CYP3A1 in rats with acute liver injury
    542. Watercress has no importance for the elimination of ethanol by CYP2E1 inhibition
    543. Inhibition of rat hepatic CYP2E1 by quinacrine: molecular modeling investigation and effects on 4-(methyl nitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced …
    544. Undernutrition during hyperoxic exposure induces CYP2E1 in rat liver
    545. Transcriptional activity of the tandem repeat polymorphism in the 5′‐flanking region of the human CYP2E1 gene
    546. Trifluoroacetylated adducts in spermatozoa, testes, liver and plasma and CYP2E1 induction in rats after subchronic inhalatory exposure to halothane
    547. A polymorphism in the 5′-flanking region of the CYP2E1 gene and elevated lung adenocarcinoma risk in a Japanese population
    548. Polymorphisms of the CYP1A1, CYP2E1 and XRCC1 genes and cancer risk in a Southern Italian population: a case–control study
    549. CYP2E1 level in rat liver injured by the interaction between carbon tetrachloride and chloroform
    550. Serum autoantibodies against cytochrome P450 2E1 (CYP2E1) predict severity of necroinflammation of recurrent hepatitis C
    551. Association of CYP2E1 of PON2311 polymorphisms in neonates with preterm
    552. Role of CYP2E1 in ketone-stimulated insulin release in pancreatic B-cells
    553. Relative roles of CYP2E1 and CYP1A2 in mouse uroporphyria caused by acetone
    554. Extrahepatic metabolism by CYP2E1 in PBPK modeling of lipophilic volatile organic chemicals: impacts on metabolic parameter estimation and prediction of dose …
    555. Use of Duplex PCR-CTPP Methods for CYP2E1 RsaI/IL-2 T-330G and IL-1B C-31T/TNF-A T-1031C Polymorphisms
    556. Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse
    557. CYP2E1 overexpression up-regulates both non-specific δ-aminolevulinate synthase and heme oxygenase-1 in the human hepatoma cell line HLE/2E1
    558. Metabolism and toxicity of the styrene metabolite 4-vinylphenol in CYP2E1 knockout mice
    559. Protein kinase C signaling as a survival pathway against CYP2E1-derived oxidative stress and toxicity in HepG2 cells
    560. Urinary excretion of 6‐hydroxychlorzoxazone as an index of CYP2E1 activity
    561. Cloning and expression of rat CYP2E1 in Saccharomyces cerevisiae: Detection of genotoxicity of N‐alkylformamides
    562. Role of the Genetic Polymorphisms in the 5′‐Flanking Region for Transcriptional Regulation of the Human CYP2E1 Gene
    563. Role of polymorphic variants of cytochrome P450 genes (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) in pathogenesis of cystic fibrosis and …
    564. Conformational anti‐cytochrome P4502E1 (CYP2E1) auto‐antibodies contribute to necro‐inflammatory injury in chronic hepatitis C
    565. Relation of GSTP1 and CYP2E1 polymorphisms with susceptibility to acute leukemia
    566. Decreased CYP2E1 mRNA expression in human leucocytes in patients with fibrotic and inflammatory lung diseases
    567. ALDH2 and CYP2E1 genotypes, urinary acetaldehyde excretion and the health consequences in moderate alcohol consumers
    568. The NH2-terminal region of rabbit CYP2E1 is not essential for interaction with NADPH-cytochrome P450 reductase
    569. Effect of high‐dose aspirin on CYP2E1 activity in healthy subjects measured using chlorzoxazone as a probe
    570. Genetic variation in the temperature dependence of liver microsomal CYP2E1 activity, within and between species of the viviparous fish Poeciliopsis
    571. Insertional polymorphism of the CYP2E1 gene in infiltrative pulmonary tuberculosis in populations of Bashkortostan Republic
    572. Cryopreserved porcine hepatocytes: expression and induction of cytochrome P450, isoform CYP2E1
    573. Comparison of levels of cytochromes P‐450, CYP1A2, CYP2E1, and their related monooxygenase activities in human surgical liver samples
    574. Modulation of ethanol-mediated CYP2E1 induction by clofibrate and L-carnitine in rat liver
    575. The effect of endotoxin on hepatocyte nuclear factor 1 nuclear protein binding: potential implications on CYP2E1 expression in the rat
    576. Effect of CYP2E1 polymorphism on DNA stability and lung cancer susceptibility
    577. Area Under the Plasma Concentration–Time Curve of Inorganic Fluoride Following Sevoflurane Anesthesia Correlates with CYP2E1 mRNA Level in Mononuclear …
    578. Identification of a 16-nucleotide sequence that mediates post-transcriptional regulation of rat CYP2E1 by insulin
    579. Fetal and maternal CYP2E1 genotypes and the risk of nonsyndromic oral clefts
    580. Bioactivation of 1, 1-dichloroethylene to its epoxide by CYP2E1 and CYP2F enzymes
    581. Exacerbation of benzene pneumotoxicity in connexin 32 knockout mice: enhanced proliferation of CYP2E1-immunoreactive alveolar epithelial cells
    582. Comparison of cytochrome P4502E1 (CYP2E1) activity and hepatic and lymphocyte mRNA expression in patients with chronic hepatitis C
    583. IL-4-mediated transcriptional regulation of human CYP2E1 by two independent signaling pathways
    584. Phorbol ester induces CYP2E1 in astrocytes, through a protein kinase C‐and tyrosine kinase‐dependent mechanism
    585. Role of phosphatidylinositol 3-kinase/AKT as a survival pathway against CYP2E1-dependent toxicity
    586. Polymorphism of the 5′‐Flanking Region of the CYP2E1 Gene: An Association Study With Alcoholism
    587. Activity of immobilised rat hepatic microsomal CYP2E1 using alumina membrane as a support
    588. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1
    589. Isolation of the mouse cytochrome P450J (CYP2E1) cDNA and its reciprocal testosterone regulation in kidney and liver
    590. Hepatotoxicity Mediated by Pyrazole (CYP2E1) Plus TNF-α Treatment Occurs in jnk2−/− but not in jnk1−/− Mice
    591. A comparison of the inhibitory effects of four volatile anaesthetics on the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
    592. Contribution of the ALDH2 and CYP2E1 genes to flushing response and drinking patterns in Japanese healthy volunteers
    593. Assessment of frequencies of lifestyle factors and polymorphisms of drug-metabolizing enzymes (NAT2, CYP2E1) in human hepatocellular carcinoma (HCC) patients …
    594. Upregulation of CYP2E1 and cyp3a activities in histamine-deficient histidine decarboxylase gene targeted mice
    595. Low-dose diethyldithiocarbamate attenuates the hepatotoxicity of 1, 3-dichloro-2-propanol and selectively inhibits CYP2E1 activity in the rat
    596. Comparison of the polymorphic regions of the cytochrome P450 CYP2E1 gene of humans and patas and cynomolgus monkeys
    597. Cytochrome p-450-mediated differential oxidative modification of proteins: albumin, apolipoprotein E, and CYP2E1 as targets
    598. Activation of alkylhydrazines to free radical intermediates by ethanol-inducible cytochrome P-4502E1 (CYP2E1)
    599. Insertion Polymorphism of the CYP2E1 gene in patients with infiltrative pulmonary tuberculosis from Bashkortostan
    600. Dichloroacetic acid treatment increases hepatic CYP2E1 in male and female rats
    601. Altered ethylbenzene-mediated hepatic CYP2E1 expression in growth hormone-deficient dwarf rats
    602. Polymorphisms of the cytochrome P450 (CYP1A1, CYP2E1) and microsomal epoxide hydrolase (mEPHX) genes in cystic fibrosis and chronic respiratory disease
    603. … , Scrophularia ningpoensis, Asparagus cochinchinensis and Ophiopogon japonicas on contents of CYP450 and activities of CYP3A, CYP2E1 and CYP1A2 in rat
    604. Genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fishes Poeciliopsis occidentalis and Poeciliopsis lucida
    605. Diminished CYP2E1 expression and formation of 2-S-glutathionyl acetate, a glutathione conjugate derived from 1, 1-dichloroethylene epoxide, in murine lung tumors
    606. Effect of 1-aminobenzotriazole on the in vitro metabolism and single-dose pharmacokinetics of chlorzoxazone, a selective CYP2E1 substrate in Wistar rats
    607. The genetic regulation of liver microsomal CYP2E1 activity among strains of the viviparous fish Poeciliopsis
    608. Bioactivation of 1, 1-dichloroethylene by CYP2E1 and CYP2F2 in murine lung
    609. Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
    610. Abnormal liver function associated with polymorphism of GSTT1, GSTM1 and CYP2E1 in workers exposed to N, N-dimethylformamide
    611. CYP2E1–Biochemical and Toxicological Aspects and Role in Alcohol-Induced Liver Injury
    612. Case-control study of the polymorphisms of CYP2E1-RsaⅠ and STT1 genes and susceptibility to pancreatic cancer
    613. Genetic polymorphisms of alcohol inducible CYP2E1 in Turkish population
    614. Expression of human CYP2E1 in insect cells using bac-to-bac expression system
    615. A Case-control study on effects of genetic polymorphisms of GSTM1, GSTT1, CYP1A1 and CYP2E1 on risk of lung cancer
    616. Glucose inhibition of the induction of CYP2E1 mRNA expression by ethanol in FGC-4 cells
    617. Effect of methacrylonitrile on cytochrome P-450 2E1 (CYP2E1) expression in male F344 rats
    618. … of liver microsomal 7-ethoxycoumarin O-deethylation and chlorzoxazone 6-hydroxylation activities in Japanese and Caucasian subjects genotyped for CYP2E1 gene
    619. No linkage of the cytochrome P-450IIE1 (CYP2E1) C1/C2 polymorphism to schizophrenia
    620. Antibodies against CYP2E1 after exposure to 1, 1, 1-trifluoroethane and 1, 1, 1, 2-tetrafluoroethane
    621. Overexpression of CYP2E1 induces HepG2 cells death by the AMP kinase activator 5′-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR)
    622. Immunohistochemical Detection of CYP2E1 and 2-S-Glutathionyl Acetate in Murine Lung Tumors: Diminished Formation of Reactive Intermediates of 1,1 …
    623. CYP2E1 genotypes and serum LAP in Japanese alcoholics
    624. Genetic polymorphisms of CYP2E1
    625. Non-positive autoimmune responses against CYP2E1 in refrigeration mechanics exposed to halogenated hydrocarbons
    626. Development of a non-high pressure liquid chromatography assay to determine [14C] chlorzoxazone 6-hydroxylase (CYP2E1) activity in human liver microsomes
    627. The colorectal cancer risk of meat intake, smoking, and CYP2E1 polymorphisms: the comparison of colorectal cancer patients with controls
    628. Genetic Polymorphism of Alcohol Metabolizing Enzymes, CYP2E1
    629. Relationship between CYP2E1 polymorphism and increase of ALT activity during therapy of patients with pulmonary tuberculosis
    630. Halothane inhalation inhibits the metabolism of chlorzoxazone, a substrate for CYP2E1, in rabbits
    631. Analysis of CYP2E1 and GSTM1 polymorphisms for the determination of genetic susceptibility to Korean patients with colon cancer
    632. Inactivation of cytochrome P-450 (CYP2E1) and carboxylesterase (hydrolase A) enzymes by vinyl carbamate in murine pulmonary microsomes
    633. Antibiotic furazolidone induces CYP1A but not CYP2E1 subfamily in rat liver
    634. Effect of starvation and acetone on the enzyme systems of biotransformation and toxicity of xenobiotics–CYP2E1 substrates in rats
    635. Comparative analysis of binding affinities between styrene and mammalian CYP2E1 by bioinformatics approaches
    636. Study of the fragmentation mechanism of protonated 6-hydroxychlorzoxazone: application in simultaneous analysis of CYP2E1 activity with major human cytochrome …
    637. Gene CYP2E1 expression in mouse liver cells exposed to low-dose radiation
    638. Interaction of polymorphisms of CYP2E1 and environmental risk factors in gastric cancer
    639. Effect of Genetic Polymorphisms of CYP2E1 and ALDH2 on the Relationship between the Levels of Urinary 8-Hydroxydeoxyguanosine and t, t-Muconic Acid
    640. Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
    641. Correlation analyses of ALDH2 and CYP2E1 genetic polymorphism with personality
    642. Variations in expression of CYP2E1 and COUP-TF1 proteins between Large White and Duroc cross-breeds
    643. GYKI-47261, a new AMPA [2-amino-3-(3-hydroxymethylisoxazole-4-yl) propionic acid] antagonist, is a CYP2E1 inducer
    644. Research on the relationship between ALDH2 and CYP2E1 gene polymorphism and alcoholic liver disease in Han people
    645. Differential expression of cytochrome P4502E1 (CYP2E1) in Morris hepatomas and livers of tumor bearing rats.
    646. A novel lipopolysaccharide‐modulated Jun binding repressor in intron 2 of CYP2E1
    647. Association analysis of alcohol metabolizing enzymes ADH1B, ADH7, CYP2E1 gene polymorphism with risk for coronary atherosclerosis
    648. Identification of polymorphisms in CYP2E1 gene and association analysis among chronic HBV patients
    649. Increase expression of CYP2E1 mRNA after methamphetamine administration in rats
    650. The role of CYP2E1 in the protection of garlic oil’s from n-hexane-induced neurotoxicity
    651. Pulmonary bioactivation of 1, 1-dichloroethylene is associated with CYP2E1 levels in A/J, CD-1, and C57BL/6 mice
    652. Ethanol-induction of cytochrome P450 2A5: permissive role for CYP2E1
    653. Characterization of a dietary ethanol protocol for CYP2E1 induction in the CD-1 mouse without evident hepatic toxicity or genotoxicity
    654. A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1
    655. Cytochemical Localization of the Acetone-lnducible Cytochrome P-450 Isoform, CYP2E1 in Murine Colonic Epithelium
    656. A study for regulation of ethanol-inducible P450 (CYP2E1) on CCl4-induced hepatic damage
    657. Associations of Rsa I polymorphism at the 5’flanking region of CYP2E1 and PON2 148 polymorphism in neonates with preterm delivery
    658. Effect of sulfur dioxide inhalation on CYP2B1/2 and CYP2E1 in rat liver and lung
    659. Genetic polymorphism of human CYP2E1: new allels detected in exons and exon-intron junctions
    660. Relationship between alcoholism and CYP2E1 genotypes
    661. A case control study on the impact of CYP2E1 and GST-M1 polymorphisms on the risk of lung cancer
    662. Preliminary effects of alcohol and Curcuma longa upon CYP2E1 and hematotoxicity in benzene-induced mice
    663. Association of genetic polymorphisms of aldehyde dehydrogenase II and CYP2E1 and clinical characteristics of patients with alcohol dependence
    664. Downregulation of the CYP2E1 ameliorates oxidative stress and apoptosis
    665. Interaction between genetic polymorphisms of CYP2E1 & NAT1 and smoking in lung cancer development (Preliminary report)
    666. Human CYP2E1 developmental expression: a role in fetal and pediatric susceptibility to toxicants?
    667. Effects of environmental carcinogens and genetic polymorphisms of CYP2E1 and NAT2 on gastric carcinogenesis
    668. Effects of Purified Glycerol from Biodiesel on Cyp1a1 and CYP2E1 Expressions in CBA/CA Mice
    669. Fast CYP2E1 genotyping using automated fluorescent detection.
    670. Association of CYP2E1, NQO1 and GST genetic polymorphisms with risk of acute lymphoblastic leukemia in turkish children
    671. Ruthenium red protects HepG2 cells overexpressing CYP2E1 against acetaminophen cytotoxicity
    672. CYP2E1 competes with CYP2B4 for limited NADPH‐Cytochrome P450 Reductase
    673. Expression and regulation of cytochrome P450 CYP2E1 in the minipig
    674. Effect of TFHL on expression of CYP2E1 in liver tissue of rats with NASH.
    675. Effects of ginsenoside Rd and Panax ginseng extract on Cyp1a, Cyp2b, Cyp2c, CYP2E1, and Cyp3a activities in C57BL/6JNarl mice
    676. The research on the relationship between CD44, CYP2E1 genetic polymorphisms and esophageal cancer
    677. Action-mechanisms of Genetic Polymorphism in the CYP2E1 on Susceptibility to Polycyclic Aromatic Hydrocarbons
    678. CYP1A1, CYP2E1 and gastric cancer risk in a high-incidence Colombian population
    679. Ontogeny of Rat CYP2E1 and CYP1A2: A Characterization and
    680. Effects of mitomycin (MMC) and {gamma}-ray irradiation on cytochrome p450 content and activities of CYP2B1 and CYP2E1 in rats
    681. The modeling of interactions of the CYP2E1 isoform of human cytochrome P450 with substrates
    682. Identification of CYP2E1-dependent genes involved in carbon tetrachloride-induced hepatotoxicity
    683. Evidence for the Existence of Two Human CYP2E1 cDNAs Using Different Polyadenylation Signals
    684. Functional polymorphism of CYP2E1 gene and alcohol use disorders in a Tibetan population.
    685. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
    686. Differential expression profile of cytochrome p450 2E1 (CYP2E1) related genes associated with carbon tetrachloride-induced hepatotoxicity
    687. Effect of total saikosaponins on the intestinal first-pass effect and liver Cyp3a, CYP2E1
    688. Relationship between gene polymorphism of CYP2E1, CYP1A1, IL-4 and medicamentosa-like dermatitis induced by trichloroethylene
    689. High dose lycopene supplementation increases hepatic CYP2E1 protein and TNF‐α expression in alcohol fed rats
    690. The ethanol elimination pharmacokinetics–the effects of genotypes of ALDH2 and CYP2E1 on the ethanol metabolism
    691. Silibinin inhibits CYP2E1‐dependent ethanol metabolism, oxidative stress and cell proliferation in a rat model of hepatocellular carcinoma (HCC)
    692. Opposite effects of isoniazid and fasting on the expression of CYP2E1 protein and mRNA in house musk shrew (Suncus murinus)
    693. Computational docking studies of nitroanisoles and nitrophenols with CYP2E1
    694. ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
    695. Role of CYP2E1 in Hepatocarcinogenesis and Hepatotoxicity
    696. An investigation of CYP2E1 phenotype determination utilizing modeling and simulation studies
    697. Formation of Multiple CYP2E1 Complexes Affects Activity
    698. Regulation of CYP2E1 and Tissue Protection Effect of CYP2E1 Inhibitor
    699. Mapping of pig CYP2E1 to SSC14
    700. ALDH and CYP2E1 Single Nucleotide Polymorphism Distribution in Korean
    701. CYP2E1 mutation associated with increased chlorzoxazone (CZ) metabolic ability
    702. Alcohol, Nicotine and Genetic Variation Influence CYP2E1
    703. Different CYP2E1 genotypes and alcoholic liver disease.
    704. Establishment and toxicological application of a cell line expressing human CYP2E1
    705. The Toxicological Mechanism Of Styrene In CYP2E1 Transgenic Cells
    706. Effect of CYP2E1 Ras I genotypes on CYP2E1 enzyme activity and DNA damage induced by phenol in immortalized human lymphocytes
    707. Effects of environmental factors on extrahepatic CYP2E1 gene expression in mice
    708. Molecular Evidence for the Presence of CYP2E1 Retropseudogene in Human Genome
    709. Role Of Mouse CYP2E1 In The O-Hydroxylation Of P-Nitrophenol: Comparison Of Activities In CYP2E1 (-/-) And Wildtype Mice
    710. Structure-functional characterization of cytochrome P4502E1 (CYP2E1)
    711. Establishment of model with exogenous human CYP2E1 expression and inducement of substrates
    712. Chlorzoxazone as a Single Sample Probe of Hepatic CYP2E1 Activity
    713. A relationship between genetic polymorphisms of CYP2E1 and susceptibility of acute leukemia in Gansu population
    714. Application of a map Bayesian method for CYP2E1 phenotyping
    715. Role of CYP2E1 Immunoglobulin G4
    716. Individual variability of CYP2E1 xenobiotic oxidation in human liver
    717. The genotype of CYP2E1 and liver-derived serum enzymes
    718. A-71G> T Nucleotide Substitution uncouples IFN-[gamma]-dependent Suppression of CYP2E1 mRNA
    719. Pathogenesis of nonalcoholic steatohohepatitis [sic]: the role of CYP2E1
    720. Hormonal regulation of CYP2E1 and CYP2C11 in rat liver and kidney
    721. Inhibition of Ethanol-induced CYP2E1 by Curcuma longa L. Extract
    722. Immunological detection of CYP2E1 in the fresh lymphocytes
    723. THE EFFECT OF COPROPHAGY ON THE EXPRESSION OF HEPATIC CYP2E1 DURING STARVATION
    724. Effects of Danshen and Its Active Components on Rat CYP2E1 Expression and Metabolism of Model CYP2E1 Probe Substrate
    725. Construction of CYP2E1 recombinant adenovirus vector and its anti-tumor effects
    726. CYP2E1-DEPENDENT BIOACTIVATION OF 191
    727. Role Of Cytochrome P450 2E1 (CYP2E1) In Trichloroethylene (TCE) Metabolism And Disposition: Comparative Studies Using CYP2E1-/-And Wild-Type Mice
    728. The role of CYP2E1 and CYP4A in the development of non-alcoholic steatohepatitis
    729. CYP2E1 VNTR polymorphisms and hepatocarcinoma: a gender-specific correlation
    730. Substrate inhibition of CYP2E1 activity is primarily determined by lipophilicity
    731. Expression of CYP2E1 gene in liver tissue in patients with hepatic cirrhosis and obstuctive jaundice
    732. Study on the association between CYP2E1 enzymes and susceptibility of alcoholic liver disease
    733. An investigation of the induction of hepatic CYP2E1 by low doses of nicotine in the rat.
    734. The Effects of CYP2E1 and CYP2C19 Polymorphisms on the Susceptibility for Gastric Cancer
    735. Time-coursed Changes of CYP2E1 Protein in Acute Liver Injury by a Single CCI₄ Administration in SD Rats
    736. Search for possible changes in murine gene CYP2E1 structural region under exposure to ionizing radiation
    737. MAPPING CONFORMATIONAL CYP2E1 EPITOPES RECOGNISED BY AUTO-ANTIBODIES IN HALOTHANE HEPATITIS AND ALCOHOLIC LIVER DISEASE
    738. The Genetic Polymorphism of CYP2E1 in a Korean Healthy Subjects and Hepatocellular Carcinoma Patients
    739. Associations between CYP2E1 promoter polymorphisms and plasma 1, 3-dimethyluric acid/theophylline ratio
    740. CYP2E1 Genetic Polymorphism relating to Styrene Metabolism of Korean Workers
    741. Pharmacokinetics of drug interactions due to ligand stabilization of CYP2E1
    742. Determination of the activity of human hepatic cytochromes P450 CYP2C8/9, CYP2E1
    743. ALLELIC VARIANTS OF CYP2E1 GENE IN HEPATOCARCINOMA PATIENTS AND IN HEPATIC TUMOR CELL LINES
    744. e0048 CYP2E1 increases oxidative stress and induces apoptosis of cardio myocytes in transgenic mice
    745. Catalytic activity and quantitation of CYP2E1 in human embryonic and fetal brain tissues
    746. Various Fatty Acids Induce Cell Damages Differently in CYP2E1-transduced HepG2 Cells, E47 Cells, Compared to C34 Cells
    747. Polymorphisms of ADH2, ALDH2 and CYP2E1 in huichol and Mestizo subjects from western México in comparison with other populations of the world
    748. Cloning and sequence analysis of human embryonic nasopharyngeal epithelial CYP2E1 cDNA
    749. The influence of Jiuganning decoction on the content of CYP2E1 and cytokine IL-6, TNF in rats models of alcoholic hepatic injury
    750. Identification of a critical CYP2E1 epitope in patients with drug-induced liver injury from anesthetics (93.16)
    751. Experimental study on effect of Erchen decoction and Taohongsiwu decoction on CYP2E1 activities in non-alcoholic fatty liver rats
    752. Use of Cytochrome P450 2E1 (CYP2E1) Knockout Transgenic Mouse Model to Study the Role of CYP2E1 in Carbon Tetrachloride-and Alcohol-mediated …
    753. The role of CYP2A6 and CYP2E1 in the metabolism of 3-methylindole in porcine hepatocytes.
    754. Role of CYP2E1 in Impaired Nitric Oxide Synthase (NOS)‐Dependent Cerebral Vasodilation During Chronic Alcohol Consumption
    755. Increased citrate levels in non-alcoholic steatohepatitis: effect on CYP2E1
    756. The Role of CYP2E1 IgG4 Subclass Autoantibodies in the Development of Anesthetic Sensitization
    757. Cutaneous CYP2E1 induction after topical treatment by dexamethasone, ethanol and salicylic acid in mouse.
    758. Meta-analysis on relationship between polymorphisms of CYP2E1 gene and susceptibility to antituberculosis drug-induced liver injury
    759. Modulation of Murine CYP2E1 Activity by Disulfiram on Trichloroethylene-Induced Neurotoxicity A Pilot Study
    760. Chlormethiazole, an inhibitor of CYP2E1, prevented chemical carcinogen-initiated and alcohol-promoted hepatic carcinongenesis in rats.
    761. Single Nucleotide Polymorphisms in the Non-coding region of CYP2E1 among Koreans
    762. The Effects of Poly IC and Human Interferon ɑ on Rat Hepatic Cyp4a1 and CYP2E1
    763. Inhibition of Urethane-Induced Carcinogenicity in CYP2E1-/-Vs. CYP2E1+/+ Mice
    764. Polymorphism of CYP2E1 gene and the risk of lung cancer among African-Americans and Caucasians in Los Angeles County (California).
    765. Association of the blood biochemical index with CYP2E1 5’flanking region Rsa I/Pst I gene polymorphism and alcohol consumption habit in Southern Taiwan …
    766. The Effects of Chungganhaeju-tang(Qingganjiejiu-tang) on Alcohol induced Cytotoxicity in CYP2E1-transfected HepG2 cells.
    767. Investigation of indazole unbinding pathways in CYP2E1 by molecular dynamics simulations
    768. CYP2E1: Mechanism of induction by isoniazid and role in acetaminophen oxidation
    769. The relationship between the GST T1, GST M1, CYP2E1 genotype and abnormal liver function in PVC workers
    770. Analyses of Mutation Frequency on the CYP2E1, ADH2, and ALDH2 Genes among Five Ethnic Groups
    771. Molecular Regulation of Ethanol-inducible P450 (CYP2E1) in Acute CCI₄Treatment
    772. CYP2E1-dependent bioactivation of 1, 1-dichloroethylene to reactive intermediates in murine and human lung and liver microsomes.
    773. CYP2E1 Mediates Ethanol-Induced DNA Damage And TNF Release In Bronchial Epithelial Cells
    774. Oral clefts, maternal exposure to solvents and CYP2E1 polymorphism
    775. Effect of γ-irradiation and mitomycin C (MMC) on CYP2B1 and CYP2E1 activities in rat hepatic microsomes in vitro
    776. The Effects of CYP2E1 on Hepatic Gene Expression in 129/Sv-CYP2E1^ tm1Gonz/J and 129S1/SvImJ Mice Exposed to Hydrazine
    777. Variable Number of Tandem Repeats (VNTR) gene polymorphism of CYP2E1 in patients with pancreatic adenocarcinoma
    778. THE EFFECT OF ETHANOL ON COUMARIN METABOLISM AND CYTOTOXICITY IN TRANSFECTED CULTURES OF HEPG2 CELLS WITH CYP2E1 EXPRESSION.