LIPOLYTIC AGENTS (REMOVES FAT)
December 8, 2023APPETITE SUPPRESSANTS
December 8, 2023
- Reversal of obesity by targeted ablation of adipose tissue
- Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkฮฒ
- Reversal of obesity-related hypoadiponectinemia by lifestyle intervention: a controlled, randomized study in obese adolescents
- Reversal of diet-induced obesity and diabetes in C57BL/6J mice
- Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats
- Leptin Activation of Corticosterone Production in Hepatocytes May Contribute to the Reversal of Obesity and Hyperglycemia in Leptin-Deficient ob/ob Mice
- Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a ฮฒ3-adrenoceptor agonist
- Trends in fatness and the origins of obesity
- Reversal of obesity in the genetically obese fa/fa Zucker rat with an ephedrine/methylxanthines thermogenic mixture
- Reversal of Obesity-and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption….
- Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity
- Obesity and sarcopenia after menopause are reversed by sex hormone replacement therapy
- Myocardial fatty acid oxidation rates remain elevated in ob/ob mice despite reversal of obesity and diabetes by caloric restriction
- Body weight regulation in obese and obese-reduced rats.
- Inflammation and the IKKฮฒ/IฮบB/NF-ฮบB axis in obesity-and diet-induced insulin resistance
- Polycythemia of obesity: further studies of its mechanism and a report of two additional cases
- Brain responses to obesogenic diets and diet-induced obesity
- Development of obesity in transgenic mice after genetic ablation of brown adipose tissue
- Hypothalamic obesity: the autonomic hypothesis and the lateral hypothalamus
- Role of Endoplasmic Reticulum Stress and c-Jun NH2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and Diabetes
- Severe orthostatic hypotension following weight reduction surgery
- The role of beta3-adrenergic receptors in control of brown and white adipose tissues and of energy balance: Reversal of obesity by CL 316,243, a new beta3ย โฆ
- The liver in obesity and type 2 diabetes mellitus
- Effects of fasting and refeeding on blood pressure are determined by nutritional state, not by body weight change
- Maternal obesity is associated with younger age at obesity onset in US adolescent offspring followed into adulthood
- Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue
- The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity
- Using mouse models to dissect the genetics of obesity
- Energy balance in reversible obesity
- Effect of diet on adipose tissue and skeletal muscle VLDL receptor and LPL: implications for obesity and hyperlipidemia
- Pathophysiologic changes of obesity
- Role of the autonomic nervous system in the development of ventromedial hypothalamic obesity
- Aspirin as a promoter of ephedrine-induced thermogenesis: potential use in the treatment of obesity
- The effects of subdiaphragmatic vagotomy in rats with ventromedial hypothalamic obesity
- Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity
- Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation
- Pathogenesis of type 2 diabetes mellitus
- Internal regulation and the evolution of normal growth as the basis for prevention of obesity in children
- A novel IKKฮฒ inhibitor stimulates adiponectin levels and ameliorates obesity-linked insulin resistance
- Obesity and alcoholic liver disease
- Acute exercise increases triglyceride synthesis in skeletal muscle and prevents fatty acidโinduced insulin resistance
- The growing problem of obesity in dogs and cats
- The cross cultural context of obesity: an INCLEN multicentre collaborative study
- Leptin: the link between adipose tissue and reproductive system
- Reduction of diet-induced obesity in rats with a herbal formulation
- Inflammation in obesity is a common link between defects in fatty acid metabolism and insulin resistance
- Increase in prevalence of obesity and diabetes and decrease in plasma cholesterol in a central Australian aboriginal community
- Obesity, past present and future
- Is there a metabolic rationale to support a weight loss programme to prevent diabetes?
- Five-year obesity incidence in the transition period between adolescence and adulthood: the National Longitudinal Study of Adolescent Health
- Increased CD36 protein as a response to defective insulin signaling in macrophages
- Adipose stress-sensing kinases: linking obesity to malfunction
- Diabetes and the endocrine pancreas II
- Controlling Obesity: School, Work, and Leisure
- Reduced skeletal muscle inhibitor of ฮบBฮฒ content is associated with insulin resistance in subjects with type 2 diabetes: reversal by exercise training
- Hyperphagia and obesity following ventromedial hypothalamic lesions in rats with subdiaphragmatic vagotomy
- The biology of white adipocyte proliferation
- Physical activity mediates a healthier body weight in the presence of obesity
- The dysregulated adipose tissue: a connecting link between insulin resistance, type 2 diabetes mellitus and atherosclerosis
- Increased activation of the mammalian target of rapamycin pathway in liver and skeletal muscle of obese rats: possible involvement in obesity-linked insulin resistance
- The hypothalamicโpituitaryโadrenal axis activity in obesity and the metabolic syndrome
- Long-term pharmacotherapy of obesity 2000: a review of efficacy and safety
- Insulin resistance: a phosphorylation-based uncoupling of insulin signaling
- Loss-of-function mutation in Toll-like receptor 4 prevents diet-induced obesity and insulin resistance
- Hyperinsulinemia in rats with hypothalamic obesity: effects of autonomic drugs and glucose
- in Obesity and Diabetes
- Regulation of 11ฮฒโHSD Genes in Human Adipose Tissue: Influence of Central Obesity and Weight Loss
- Adrenal and gonadal function in obesity
- CCR2 modulates inflammatory and metabolic effects of high-fat feeding
- Nitrosative stress and pathogenesis of insulin resistance
- The genetics of human obesity
- Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
- Neuropeptides, appetite regulation, and human obesity
- DHEA protects against visceral obesity and muscle insulin resistance in rats fed a high-fat diet
- Adipokines: molecular links between obesity and atheroslcerosis
- Plasminogen activator inhibitor-1, inflammation, obesity, insulin resistance and vascular risk
- Adipokines: at the heart of the relationship between obesity and insulin resistance.
- The metabolic syndrome as a risk factor for chronic kidney disease: more than a fat chance?
- Obesity: overview of prevalence, etiology, and treatment
- Adipokines, inflammation, and the endothelium in diabetes
- A role for iNOS in fasting hyperglycemia and impaired insulin signaling in the liver of obese diabetic mice
- Molecular mechanisms of insulin resistance: serine phosphorylation of insulin receptor substrate-1 and increased expression of p85ฮฑ: the two sides of a coin
- Low-grade inflammation, obesity, and insulin resistance in adolescents
- Surgical management of obesity
- Impaired transport of leptin across the blood-brain barrier in obesity is acquired and reversible
- Subclinical inflammation and obesity, diabetes and related disorders
- Optimal management of the morbidly obese patient SAGES appropriateness conference statement
- Dietary Cyanidin 3-O-ฮฒ-D-Glucoside-Rich Purple Corn Color Prevents Obesity and Ameliorates Hyperglycemia in Mice
- Hepatic expression of malonyl-CoA decarboxylase reverses muscle, liver and whole-animal insulin resistance
- Metabolic syndrome, hyperinsulinemia, and cancer
- Evidence for alteration of the vitamin D-endocrine system in obese subjects.
- Pharmacological treatment of obesity: therapeutic strategies
- A rational approach to pathogenesis and treatment of type 2 diabetes mellitus, insulin resistance, inflammation, and atherosclerosis
- Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells
- Neuroendocrine and metabolic effects of adipocyte-derived hormones
- Cellular inflammatory responses: novel insights for obesity and insulin resistance
- Tumor necrosis factor and its potential role in insulin resistance and nonalcoholic fatty liver disease
- Local and systemic insulin resistance resulting from hepatic activation of IKK-ฮฒ and NF-ฮบB
- Insulin resistance and the pathogenesis of nonalcoholic fatty liver disease
- Nonalcoholic fatty liver disease: Cytokine-adipokine interplay and regulation of insulin resistance
- Obesity-induced inflammatory changes in adipose tissue
- A burning question: does an adipokine-induced activation of the immune system mediate the effect of overnutrition on type 2 diabetes?
- Ciliary neurotrophic factor corrects obesity and diabetes associated with leptin deficiency and resistance
- Obesity and androgens: facts and perspectives
- Antidiabetic Effects of cis-9, trans-11โConjugated Linoleic Acid May Be Mediated via Anti-Inflammatory Effects in White Adipose Tissue
- Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes
- Search for obesity drugs: targeting central and peripheral pathways
- #VALUE!
- Adipsin and an endogenous pathway of complement from adipose cells.
- Decreased insulin receptor (IR) autophosphorylation in fibroblasts from patients with PCOS: effects of serine kinase inhibitors and IR activators
- Surgery for obesity: a review of the current state of the art and future directions
- Regulation of energy balance in two models of reversible obesity in the rat.
- Type 2 diabetes: principles of pathogenesis and therapy
- The rise, fall, and resurrection of the ventromedial hypothalamus in the regulation of feeding behavior and body weight
- Comparison of short-term diet and exercise on insulin action in individuals with abnormal glucose tolerance
- Inflammatory markers, adiponectin, and risk of type 2 diabetes in the Pima Indian
- Tumor necrosis factor ฮฑ-induced skeletal muscle insulin resistance involves suppression of AMP-kinase signaling
- Pathophysiology of obesity-induced insulin resistance and type 2 diabetes mellitus
- Inhibitors of preadipocyte replication: opportunities for the treatment of obesity
- Obesity and endothelial function
- Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
- Laparoscopic Roux-en-Y gastric bypass for recalcitrant gastroesophageal reflux disease in morbidly obese patients
- The evolving role of inflammation in obesity and the metabolic syndrome
- Free fatty acids produce insulin resistance and activate the proinflammatory nuclear factor-ฮบB pathway in rat liver
- 7 Bariatric Surgery for Obesity
- Adipose tissue macrophages
- Nonalcoholic fatty liver disease and the epidemic of obesity
- The Prevalence and Treatment of Obesity in Adolescence (Weight Control)
- Increased in vivo regeneration of cortisol in adipose tissue in human obesity and effects of the 11ฮฒ-hydroxysteroid dehydrogenase type 1 inhibitor carbenoxolone
- MCHโ/โ Mice Are Resistant to Aging-Associated Increases in Body Weight and Insulin Resistance
- Inflammation, stress, and diabetes
- Novel targets and therapeutic strategies for type 2 diabetes
- Inflammation and activated innate immunity in the pathogenesis of type 2 diabetes
- Macrophage-secreted factors induce adipocyte inflammation and insulin resistance
- Insulin sensitizers may prevent metabolic inflammation
- Effects of antiglucocorticoid RU 486 on development of obesity in obese fa/fa Zucker rats
- Conditional disruption of IฮบB kinase 2 fails to prevent obesity-induced insulin resistance
- Effects of gonadectomy on glucocorticoid metabolism in obese Zucker rats
- Oxidative inflammatory stress in obesity and diabetes
- Combined leptin actions on adipose tissue and hypothalamus are required to deplete adipocyte fat in lean rats: implications for obesity treatment
- Inflammation, atherosclerosis, and aspects of insulin action
- Hyperglycemia, maturity-onset obesity, and insulin resistance in NONcNZO10/LtJ males, a new mouse model of type 2 diabetes
- Increased insulin and leptin sensitivity in mice lacking acyl CoA: diacylglycerol acyltransferase 1
- Low-grade systemic inflammation and the development of type 2 diabetes: the atherosclerosis risk in communities study
- Insulin resistance in adipose tissue: direct and indirect effects of tumor necrosis factor-ฮฑ
- 11ฮฒ-Hydroxysteroid dehydrogenase type 1 in obesity and the metabolic syndrome
- Effect of a ฮฒ-3 agonist on food intake in two strains of rats that differ in susceptibility to obesity
- Tackling obesities: future choices-project report
- Role of Ser/Thr kinases in the uncoupling of insulin signaling
- Obesity, peroxisome proliferator-activated receptor, and atherosclerosis in type 2 diabetes
- Transplantation of pancreatic beta-cells prevents development of hypothalamic obesity in rats.
- An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial
- AntiโInflammatory and Antidiabetic Roles of PPARฮณ
- Emerging pharmacological approaches to the treatment of obesity
- Differential effects of interleukin-6 and-10 on skeletal muscle and liver insulin action in vivo
- Prospective study of C-reactive protein in relation to the development of diabetes and metabolic syndrome in the Mexico City Diabetes Study
- Insulin resistance in hepatocytes and sinusoidal liver cells: mechanisms and consequences
- Increased glucocorticoid receptor and 11ฮฒ-hydroxysteroid dehydrogenase type 1 expression in hepatocytes may contribute to the phenotype of type 2 diabetes in dbย โฆ
- Adipocyte-specific overexpression of FOXC2 prevents diet-induced increases in intramuscular fatty acyl CoA and insulin resistance
- Current knowledge in the neurophysiologic modulation of obesity
- Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity.
- Role of energy charge and AMP-activated protein kinase in adipocytes in the control of body fat stores
- Regulated membrane transport of free fatty acids in adipocytes: role in obesity and non-insulin dependent diabetes mellitus.
- Weight loss increases 11ฮฒ-hydroxysteroid dehydrogenase type 1 expression in human adipose tissue
- New approaches in the pharmacological treatment of obesity
- Leptin and the treatment of obesity: its current status
- Short-and long-term beneficial effects of a multidisciplinary therapy for the control of metabolic syndrome in obese adolescents
- Inflammation and insulin resistance
- Reduced adipose glucocorticoid reactivation and increased hepatic glucocorticoid clearance as an early adaptation to high-fat feeding in Wistar rats
- Long-term caffeine consumption exacerbates renal failure in obese, diabetic, ZSF1 (fa-facp) rats
- Insulin signalling and the regulation of glucose and lipid metabolism
- Obesity-related differential gene expression in the visceral adipose tissue
- Aging up-regulates expression of inflammatory mediators in mouse adipose tissue
- IKK-ฮฒ links inflammation to obesity-induced insulin resistance
- Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea
- Adipose tissue as source and target for novel therapies
- Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial
- Increase in glucose-6-phosphate dehydrogenase in adipocytes stimulates oxidative stress and inflammatory signals
- Keynote review: the adipocyte as a drug discovery target
- Aspirin inhibits serine phosphorylation of IRS-1 in muscle and adipose tissue of septic rats
- Obesity, inflammation, and insulin resistance
- Genistein decreases food intake, body weight, and fat pad weight and causes adipose tissue apoptosis in ovariectomized female mice
- Diabetes and obesity: part 1
- Molecular and genetic studies examining the inflammatory consequences of obesity
- Prevention of genetic fa/fa obesity with an ephedrine-methylxanthines thermogenic mixture
- Inflammatory cytokines and the risk to develop type 2 diabetes: results of the prospective population-based European Prospective Investigation into Cancer andย โฆ
- Obesity: Overview & Management
- Improvement in risk factors for metabolic syndrome and insulin resistance in overweight youth who are treated with lifestyle intervention
- C-reactive protein is an independent predictor of risk for the development of diabetes in the West of Scotland Coronary Prevention Study
- Inflammatory mechanisms in diabetes: lessons from the ฮฒ-cell
- Aspirin inhibits serine phosphorylation of insulin receptor substrate 1 in growth hormone treated animals
- Mediators of cytokine-induced insulin resistance in obesity and other inflammatory settings
- Type 2 diabetes and obesity in children and adolescents: experience from studies in Taiwanese population
- Ceramides in insulin resistance and lipotoxicity
- Resistin-and obesity-associated metabolic diseases
- Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes
- Adipocyte/macrophage fatty acid binding proteins control integrated metabolic responses in obesity and diabetes
- The emerging role of adipokines as mediators of cardiovascular function: physiologic and clinical perspectives
- A primer on bariatric surgery: treatment of last resort for morbid obesity
- Anti-obesity and anti-tumor pro-apoptotic peptides are sufficient to cause release of cytochrome c from vesicles
- Obesity, insulin resistance, and renal function
- Data-mining analysis suggests an epigenetic pathogenesis for type 2 diabetes
- Adipocytokines: mediators linking adipose tissue, inflammation and immunity
- New drug targets for type 2 diabetes and the metabolic syndrome
- Diet-induced obesity and acute hyperlipidemia reduce IฮบBฮฑ levels in rat skeletal muscle in a fiber-type dependent manner
- Genetic variability affects the development of brown adipocytes in white fat but not in interscapular brown fatsโ
- Diabesity: an inflammatory metabolic condition
- Peroxisome proliferator-activated receptor-ฮฑ deficiency does not alter insulin sensitivity in mice maintained on regular or high-fat diet: hyperinsulinemic-euglycemicย โฆ
- Pathogenic role of inflammatory cytokines in obesity: from insulin resistance to diabetes mellitus
- Thiazolidinediones influence plasma steroids of male obese Zucker rats
- Loss of cyclinโdependent kinase inhibitors produces adipocyte hyperplasia and obesity
- Beyond the scale: understanding mechanisms of weight gain and obesity in diabetes
- Adiponectin and hypertension: a putative link between adipocyte function and atherosclerotic risk?
- Sibutramine-dependent brown fat activation in rats: an immunohistochemical study
- 12: Does physical activity help weight loss in obesity?
- Adipogenesis in obesity requires close interplay between differentiating adipocytes, stromal cells, and blood vessels
- Heterogeneity of adipose tissue metabolism
- The contribution of visceral adipose tissue to splanchnic cortisol production in healthy humans
- The anti-inflammatory and potential anti-atherogenic effect of insulin: a new paradigm
- Prevalence, predisposition and prevention of type II diabetes
- Neurohumoral regulation of body weight gain
- Sulfasalazine and BAY 11-7082 interfere with the nuclear factor-ฮบB and IฮบB kinase pathway to regulate the release of proinflammatory cytokines from human adiposeย โฆ
- Induction of heat shock proteins may combat insulin resistance
- Obesity in Later Childhood and Countermeasures
- Lipid-induced insulin resistance in human muscle is associated with changes in diacylglycerol, protein kinase C, and IฮบB-ฮฑ
- 2 Steps for the Medical Evaluation of the Obese Patient
- Exercise alone reduces insulin resistance in obese children independently of changes in body composition
- Evolutionary origins of insulin resistance: a behavioral switch hypothesis
- TLR4 links innate immunity and fatty acidโinduced insulin resistance
- Improving effect of carteolol on bodyweight and carbohydrate and lipid metabolic responses in the OLETF rat
- Liver X receptor agonist T0901317 inhibition of glucocorticoid receptor expression in hepatocytes may contribute to the amelioration of diabetic syndrome in db/dbย โฆ
- Are oxidative stressโ activated signaling pathways mediators of insulin resistance and ฮฒ-cell dysfunction?
- PKC-mediated modulation of L-type calcium channels may contribute to fat-induced insulin resistance
- 11 [beta]-hydroxysteroid dehydrogenase type 1 in obesity
- Role of adipocytokines in metabolism and disease
- New insights into the pathophysiology of gestational diabetes mellitus: possible role of human leukocyte antigen-G
- Factors influencing body weight regulation
- Inhibitor ฮบB kinase is involved in the paracrine crosstalk between human fat and muscle cells
- Mechanisms of the antidiabetic effects of the ฮฒ3-adrenergic agonist CL-316243 in obese Zucker-ZDF rats
- Tumor necrosis factor (TNF) interferes with insulin signaling through the p55 TNF receptor death domain
- Salicylate prevents hepatic insulin resistance caused by short-term elevation of free fatty acids in vivo
- Contribution of sphingolipids to the pathogenesis of obesity
- Autoamplification of tumor necrosis factor-ฮฑ: a potential mechanism for the maintenance of elevated tumor necrosis factor-ฮฑ in male but not female obese mice
- Insulin receptor substrate proteins and diabetes
- Neuroendocrinology of insulin resistance: metabolic and endocrine aspects of adiposity
- Increase in insulin action and fat oxidation after treatment with CL 316,243, a highly selective beta3-adrenoceptor agonist in humans.
- Interleukin-6 induces cellular insulin resistance in hepatocytes
- Les relations entre obรฉsitรฉ, inflammation et insulinorรฉsistance: acquisitions rรฉcentes
- Tumor necrosis factor-ฮฑ suppresses adipocyte-specific genes and activates expression of preadipocyte genes in 3T3-L1 adipocytes: nuclear factor-ฮบB activation byย โฆ
- Acetylsalicylic acid improves lipid-induced insulin resistance in healthy men
- A sympathetic defense against obesity
- Sex steroids and leptin regulate 11ฮฒ-hydroxysteroid dehydrogenase I and P450 aromatase expressions in human preadipocytes: sex specificities
- Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteinsย โฆ
- Unexpected deposition of brown fat in mammary gland during postnatal development
- Potential utility of natural polyphenols for reversing fat-induced insulin resistance
- Turning down insulin signaling
- Female rats do not exhibit free fatty acidโinduced insulin resistance
- A clinical guide to pediatric weight management and obesity
- Fat, diabetes, and liver injury in chronic hepatitis C
- Molecular basis of insulin action
- Diabetic pregnancy in rats leads to impaired glucose metabolism in offspring involving tissue-specific dysregulation of 11ฮฒ-hydroxysteroid dehydrogenase type 1ย โฆ
- Control of body weight: a physiologic and transgenic perspective
- Stearoyl CoA desaturase 1 is elevated in obesity but protects against fatty acid-induced skeletal muscle insulin resistance in vitro
- Differential effects of rosiglitazone on skeletal muscle and liver insulin resistance in A-ZIP/F-1 fatless mice
- Skeletal muscle and obesity
- SR59230A blocks ฮฒ3-adrenoceptor-linked modulation of uncoupling protein-1 and leptin in rat brown adipocytes
- Adipose tissue remodeling and malfunctioning in obesity revealed by in vivo molecular imaging
- Muscle triglyceride and insulin resistance
- Multilocular fat cells in WAT of CL-316243-treated rats derive directly from white adipocytes
- Risk factors for progression to incident hyperinsulinemia: the Atherosclerosis Risk in Communities Study, 1987โ1998
- Unraveling the cellular mechanism of insulin resistance in humans: new insights from magnetic resonance spectroscopy
- Studies on the sympathetic efferent nerves of brown adipose tissue of lean and obese Zucker rats
- Antioxidants: do they have a role in the treatment of insulin resistance?
- Transcriptional control of brown fat determination by PRDM16
- AAV-mediated leptin receptor installation improves energy balance and the reproductive status of obese female Koletsky rats
- Transcriptional synergy and the regulation of Ucp1 during brown adipocyte induction in white fat depots
- Macrophages block insulin action in adipocytes by altering expression of signaling and glucose transport proteins
- Preclinical developments in type 2 diabetes
- NEUROPEPTIDE, OPIOID RECEPTOR, AND BEHAVIORAL CHANGES FOLLOWING OBESITY-INDUCING VENTROMEDIAL HYPOTHALAMIC LESIONSย โฆ
- Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines
- Disordered lipid metabolism and the pathogenesis of insulin resistance
- Lifestyle modification and endothelial function in obese subjects
- White adipose tissue contributes to UCP1-independent thermogenesis
- Insulin resistance, inflammation, and the IKK/IฮบB/NF-ฮบB pathway
- ALS/Lt: a new type 2 diabetes mouse model associated with low free radical scavenging potential
- Metformin prevents the development of acute lipid-induced insulin resistance in the rat through altered hepatic signaling mechanisms
- Lipids and glucose in type 2 diabetes: what is the cause and effect?
- Type 1 diabetes is associated with increased cyclooxygenase-and cytokine-mediated inflammation
- #VALUE!
- Insulin signaling pathways in time and space
- NASH as part of the metabolic (insulin resistance) syndrome
- Dehydroepiandrosterone inhibits the amplification of glucocorticoid action in adipose tissue
- Glucocorticoids and 11beta-hydroxysteroid dehydrogenase in adipose tissue
- Energy metabolism in genetically fat and lean birds and mammals
- Insulin resistance, inflammation, and the ikk/ikb/nf-kb pathway
- Insulin resistance in NAFLD: Potential mechanisms and therapies
- Pathogenesis of type 2 diabetes
- The role of AEBP1 in sex-specific diet-induced obesity
- Mitochondrial dysfunction and type 2 diabetes
- Nitric oxide-induced downregulation of leptin production by 3T3-L1 adipocytes
- Insulin resistance, inflammation, and the IKK/IะบB/NF-ะบB pathway
- Aspirin and diabetes: inhibition of amylin aggregation by nonsteroidal anti-inflammatory drugs
- LXRs regulate the balance between fat storage and oxidation
- Tag Polymorphisms at the A20 (TNFAIP3) Locus Are Associated With Lower Gene Expression and Increased Risk of Coronary Artery Disease in Type 2 Diabetes
- Adiponectin: a key fat-derived molecule regulating inflammation
- The inflammatory response is an integral part of the stress response: Implications for atherosclerosis, insulin resistance, type II diabetes and metabolic syndrome X
- Future Pharmacotherapy for Obesity: Integration of Metabolism and Body Weight Regulation
- Inflammation and its relationship to insulin resistance, type 2 diabetes mellitus, and endothelial dysfunction
- Dexamethasone impairs insulin signalling and glucose transport by depletion of insulin receptor substrate-1, phosphatidylinositol 3-kinase and protein kinase B inย โฆ
- PKCฮป in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
- Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms
- Molecular mechanisms of insulin resistance in humans and their potential links with mitochondrial dysfunction
- Effect of a high or low ambient perinatal temperature on adult obesity in Osborne-Mendel and S5B/Pl rats
- The effect of tea polyphenols on chronic disease: obesity, the metabolic syndrome, and colon cancer
- Abscisic acid ameliorates glucose tolerance and obesity-induced inflammation
- Aspirin, NSAIDs, and colorectal cancer: possible involvement in an insulin-related pathway
- C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men
- Three mitogen-activated protein kinases inhibit insulin signaling by different mechanisms in 3T3-L1 adipocytes
- The Apparent Increase in Insulin Sensitivity of Leptin-Treated Rats Appears to be Due to a Decrease in Blood Glucose Concentrations in Response to Fasting
- Long-term multidisciplinary therapy decreases predictors and prevalence of metabolic syndrome in obese adolescents
- #VALUE!
- Not the next tobacco: Defenses to obesity claims
- Obesity and nutrition
- Drug Therapy for Insulin Resistanceโa Look at the Future
- Adiponectin oligomers in human serum during acute and chronic exercise: relation to lipid metabolism and insulin sensitivity
- Kinase-dependent pathways and the development of insulin resistance in hepatocytes
- Effect of high-fat diet on KKAy and ob/ob mouse liver and adipose tissue corticosterone and 11-dehydrocorticosterone concentrations
- Mechanisms of insulin resistance in humans and possible links with inflammation
- Development and evaluation of a nutrition curriculum to prevent obesity in inner-city teens
- Cardiac-specific overexpression of peroxisome proliferatorโactivated receptor-ฮฑ causes insulin resistance in heart and liver
- Arsenic-induced alteration in the expression of genes related to type 2 diabetes mellitus
- Increased glucose uptake promotes oxidative stress and PKC-ฮด activation in adipocytes of obese, insulin-resistant mice
- Molecular and cellular aspects of insulin resistance: implications for diabetes
- Receptors for insulin, NSILA-s, and growth hormone: applications to disease states in man
- Non-alcoholic fatty liver disease and insulin resistance
- Role of oxidative stress and inflammation in the origin of Type 2 diabetesโa paradigm shift
- Serum concentrations of resistin-like molecules ฮฒ and ฮณ are elevated in high-fat-fed and obese db/db mice, with increased production in the intestinal tractย โฆ
- Reactive species, cellular repair and risk factors in the onset of type 2 diabetes mellitus: review and hypothesis
- Energy expenditure, body composition, and glucose metabolism in lean and obese rhesus monkeys treated with ephedrine and caffeine
- Role of the Toll-like receptor 4/NF-ฮบB pathway in saturated fatty acidโinduced inflammatory changes in the interaction between adipocytes and macrophages
- Salicylates targeting insulin resistance
- COMMENT: Genetic Variability in Insulin Action Inhibitor Ikkฮฒ (IKBKB) Does Not Play a Major Role in the Development of Type 2 Diabetes
- Lowering plasma free fatty acids with Acipimox mimics the antidiabetic effects of the [beta] 3-adrenergic agonist CL-316243 in obese Zucker diabetic fatty rats
- Bradykinin Augments Insulin-Stimulated Glucose Transport in Rat Adipocytes via Endothelial Nitric Oxide SynthaseโMediated Inhibition of Jun NH2-Terminal Kinase
- Obesity-associated interleukin-6 contributes to hepatic insulin resistance in mice
- Kinome analysis reveals nongenomic glucocorticoid receptor-dependent inhibition of insulin signaling
- Feeding scallop shell powder induces the expression of uncoupling protein 1 (UCP1) in white adipose tissue of rats
- The macrophage at the crossroads of insulin resistance and atherosclerosis
- Molecular mechanisms of diabetic vasculopathy
- Hormone-sensitive lipase knockout mice have increased hepatic insulin sensitivity and are protected from short-term diet-induced insulin resistance in skeletal muscleย โฆ
- Central nervous system regulation of fat cell lipid mobilization: The role of the sympathetic nervous system
- Treatment of insulin resistance in diabetes mellitus
- Adiponectin and leptin: potential tools in the differential diagnosis of pediatric diabetes?
- Inflamed adipose tissue: a culprit underlying the metabolic syndrome and atherosclerosis
- Sympathetic innervation of white adipose tissue and its regulation of fat cell number
- Mechanisms underlying fat-induced hepatic insulin resistance
- #VALUE!
- Metabolic and cellular plasticity in white adipose tissue I: effects of ฮฒ3-adrenergic receptor activation
- Insulin is an anti-inflammatory and anti-atherosclerotic hormone
- Profiling of the secreted proteins during 3T3-L1 adipocyte differentiation leads to the identification of novel adipokines
- Free fatty acid-induced insulin resistance in the obese is not prevented by rosiglitazone treatment
- Phosphorylation of fetuin-A, a physiological inhibitor of insulin action, regulated by insulin and leptin
- Functional characterization of resistin, a novel adipokine
- Regulating insulin signaling and ฮฒ-cell function through IRS proteins
- Role of cyclin-dependent kinase inhibitors in estrogen regulation of adipogenesis
- The effect of salicylates on insulin sensitivity
- Adipokine expression and secretion: a target for pharmacologic treatment
- Cells of the stroma-vascular fraction of human adipose tissue: characterization and function
- Modulation of insulin action
- Advanced-glycation end products in insulin-resistant states
- Pathophysiology of NASH: insulin resistance, free fatty acids and oxidative stress
- The hormone leptin reduces body weight. A mutant gene makes the mouse obese
- Inflammatory mediators and islet ฮฒ-cell failure: a link between type 1 and type 2 diabetes
- #VALUE!
- Effects of pioglitazone on promoting energy storage, not expenditure, in brown adipose tissue of obese fa/fa Zucker rats: comparison to CL 316,243
- PKCฮป in liver mediates insulin-induced SREBP-1c expression and determines both hepatic lipid content and overall insulin sensitivity
- Inflammatory markers and type 2 diabetes
- The ฮฒ3-adrenergic agonist CL316, 243 inhibits insulin signaling but not glucose uptake in primary human adipocytes
- Mechanism by which high-dose aspirin improves glucose metabolism in type 2 diabetes
- Rosiglitazone ameliorates insulin resistance in brown adipocytes of Wistar rats by impairing TNF-ฮฑ induction of p38 and p42/p44 mitogen-activated proteinย โฆ
- Adipocyte differentiation induces dynamic changes in NF-ฮบB expression and activity
- 25 Insulin Resistance Syndrome and Its Vascular Complications
- Adiposopathy: how do diet, exercise and weight loss drug therapies improve metabolic disease in overweight patients?
- Association between Helicobacter felisโInduced Gastritis and Elevated Glycated Hemoglobin Levels in a Mouse Model of Type 1 Diabetes
- Neuropeptide and peripheral hormone crosstalk with adipocyte function
- Prevention of cardiovascular complications of diabetes mellitus by aspirin
- THE ANTI-INFLAMMATORY AND POTENTIAL ANTI-ATHEROGENIC EFFECT OF INSULIN
- Selenium acts as an insulin-like molecule for the down-regulation of diabetic symptoms via endoplasmic reticulum stress and insulin signalling proteins in diabetesย โฆ
- The aging pancreas, glucose tolerance and insulin action
- Correction of insulin resistance and the metabolic syndrome
- Endothelium, inflammation, and diabetes
- Prevention of fat-induced insulin resistance by salicylate
- Patents in Targets and Drugs for Insulin Resistance: Correlation with Inflammatory Mediators
- Treating insulin resistance: future prospects
- Transgenic Models of Impaired Insulin Signaling
- Insulin resistance, hypertension and endothelial dysfunction
- The expanding scope of the metabolic syndrome and implications for the management of cardiovascular risk in type 2 diabetes with particular focus on the emergingย โฆ
- Inactivation of fatty acid transport protein 1 prevents fat-induced insulin resistance in skeletal muscle
- Adult stem cells for cardiovascular diseases: the adipose tissue potential
- A role of vitamin D in low-intensity chronic inflammation and insulin resistance in type 2 diabetes mellitus?
- Mitochondrial factors in the pathogenesis of diabetes: a hypothesis for treatment
- Investigation of the alternative pathway of complement in the biology of white and brown adipocytes
- Effectiveness of a Christian faith-based program for weight loss
- Increased in vivo phosphorylation of insulin receptor at serine 994 in the liver of obese insulin-resistant Zucker rats
- Glucocorticoid administration: Studies on weight regulation and metabolic implications
- Role of insulin resistance and insulin secretory dysfunction in the pathogenesis of type 2 diabetes mellitus: lessons from cross-sectional, prospective, and longitudinalย โฆ
- The relationship between high-fat feeding, insulin resistance, and TNF-ฮฑ gene expression in growing rats
- ฮฒ1 to ฮฒ3 Switch in Control of Cyclic Adenosine Monophosphate during Brown Adipocyte Development Explains Distinct ฮฒ-Adrenoceptor Subtype Mediation ofย โฆ
- Glucocorticoids produce whole body insulin resistance with changes in cardiac metabolism
- The metabolic and molecular regulation of adipose triglyceride lipase
- Short-term lifestyle intervention significantly increases fasting adiponectin and induces a decline in serum adiponectin during oral glucose tolerance test, withoutย โฆ
- Aspirin and diabetes
- PTEN and SHIP2 phosphoinositide phosphatases as negative regulators of insulin signalling
- Antioxidants in diabetic complications and insulin resistance
- Aspirin at low-intermediate concentrations protects retinal vessels in experimental diabetic retinopathy through nonโplatelet-mediated effects
- IRS proteins and the common path to diabetes
- Macrophage PPARฮณ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
- Syndromes of Severe Insulin Resistance (SSIRs)
- Suppression of DGAT2 Expression Improves Hepatic Steatosis and Prevents Fat Induced Insulin Resistance
- Timp3 deficiency in insulin receptorโhaploinsufficient mice promotes diabetes and vascular inflammation via increased TNF-ฮฑ
- Impact of trans-10, cis-12 conjugated linoleic acid on interleukin (IL)-6 and IL-8 and adipogenic genes in cultures of human adipose tissue explants
- STATโ3 and the liver: A new station on our way to understand diabetes?
- Functional anatomy of the ‘Adipose Organ’
- Molecular basis of coordination of adipocyte metabolic and inflammatory responses
- Age-and sex-related reference values for serum insulin concentration and its biological determinants in a French healthy population. The STANISLAS cohort
- Macrophage peroxisome proliferator activated receptor ฮณ as a therapeutic target to combat type 2 diabetes
- Cell Signaling Properties of a-Lipoic Acid: Implications in Type 2 Diabetes
- an unexpected virusโhost interactionโthe hepatitis C virusโdiabetes link
- Comparison of isoenergetic aerobic versus aerobic plus resistance exercise program during a weight loss program
- Tumor necrosis factor ฮฑ produces insulin resistance in skeletal muscle by activation of inhibitor ฮบB kinase in a p38 MAPK-dependent manner
- Real-time RT-PCR and proteomic analysis of adipose tissue from ob/ob mice treated with leptin
- Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance
- The role of GSK3 in glucose homeostasis and the development of insulin resistance
- The relationship of the Diet Quality Index to prevalence of overweight in black and white adolescent girls: an examination of data from the National Heart, Lung, andย โฆ
- On endothelial function in type 2 diabetic patients with coronary artery disease
- Type 2 diabetes impairs interleukin-4 function in macrophages and amplifies the brain-based neuroimmune response
- Insulin Signalling and Regulation of Protein kinase B in Adipocytes
- Stress and Type 2 diabetes
- Insulin Resistance
- Pi 3-kinase and its up-and down-stream modulators as potential targets for the treatment of type II diabetes
- The Selenium Significantly Activated the ER Stress Signaling Pathway in the Diabetes-Susceptible NOD Mice
- Relationships between low-density lipoprotein particle size, plasma lipoproteins, and progression of coronary artery disease: the Diabetes Atherosclerosis Interventionย โฆ
- Gliclazide protects 3T3L1 adipocytes against insulin resistance induced by hydrogen peroxide with restoration of GLUT4 translocation
- Effect of Huanglian Jiedu Decoction on Glucose Transporter 4 Expression in Adipose and Skeletal Muscle Tissues of Insulin Resistant Rats.
- Plasma arachidonic acid influences insulin-stimulated glucose uptake in healthy adult women
- Mechanisms of cardiovascular complications in diabetes and potential new pharmacological therapies
- Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids
- Diabetes, inflammation, proinflammatory cytokines, and diabetic nephropathy
- Future targets in the treatment of type 2 diabetes
- Gene expression of 11ฮฒ-hydroxysteroid dehydrogenase type 1 and type 2 in the kidneys of insulin-dependent diabetic rats
- Long-term effects of recombinant human insulin-like growth factor I treatment on glucose and lipid metabolism and the growth of a patient with congenital generalizedย โฆ
- Inhibition of translation and insulin signaling by p21-activated protein kinase 2 (Pak2)
- Oxidative stress induces insulin resistance by activating the nuclear factor-ฮบB pathway and disrupting normal subcellular distribution of phosphatidylinositol 3ย โฆ
- Detecting type 2 diabetes by a single post-challenge blood sample
- Insulin and cellular stress induced glucose uptake in 3T3-L1 adipoc tes
- Cyclooxygenase-2 (PTGS2) inhibitors augment the rate of hexose transport in L6 myotubes in an insulin-and AMPKฮฑ-independent manner
- Ceramida como mediador de la resistencia a insulina producida por el factor de necrosis tumoral alfa en adipocitos marrones
- Influence of calorie restriction on insulin signalling and glucose transport in skeletal muscle of rats
- Prevention and reversal of obesity and glucose intolerance in mice by DHA derivatives
- Reversal of obesity and insulin resistance by a non-peptidic glucagon-like peptide-1 receptor agonist in diet-induced obese mice
- Childhood obesity
- Predictors of chronic disease at midlife and beyond-the health risks of obesity
- Food reward functions as affected by obesity and bariatric surgery
- Inflammation in obesity-related diseases
- Chronic administration of brain-derived neurotrophic factor in the hypothalamic paraventricular nucleus reverses obesity induced by high-fat diet
- Dietary curcumin significantly improves obesity-associated inflammation and diabetes in mouse models of diabesity
- Eicosapentaenoic acid prevents and reverses insulin resistance in high-fat diet-induced obese mice via modulation of adipose tissue inflammation
- Obesity and CKD: how to assess the risk?
- Risks and management of obesity in pregnancy: current controversies
- Brown adipose tissue and seasonal variation in humans
- Vascular targeting of adipose tissue as an anti-obesity approach
- Applying Brainpower to Obesity
- Changes in adiposity status from childhood to adolescence: A 6-year longitudinal study in Portuguese boys and girls
- Differential effects of calorie restriction and exercise on the adipose transcriptome in diet-induced obese mice
- n-3 Fatty acids and rosiglitazone improve insulin sensitivity through additive stimulatory effects on muscle glycogen synthesis in mice fed a high-fat diet
- Mechanical stimulation of mesenchymal stem cell proliferation and differentiation promotes osteogenesis while preventing dietaryโinduced obesity
- Normalization of obesity-associated insulin resistance through immunotherapy
- A putative role for apelin in the etiology of obesity
- The effect of obesity on sperm disorders and male infertility
- Prevention of obesity in preschool children
- Response of fractional synthesis rate (FSR) of fibrinogen, concentration of Dโdimer and fibrinolytic balance to physical activityโbased intervention in obeseย โฆ
- Association between obesity and atopic dermatitis in childhood: a case-control study
- Obesity-Induced Inflammation and Insulin Resistance
- Obesity and Related Co-Morbid ConditionsโA Retrograde Study
- Changing the future of obesity: science, policy, and action
- Adipokines in obesity
- A potential role for insulin in management of the metabolic syndrome
- โLikingโ and โwantingโ of sweet and oily food stimuli as affected by high-fat diet-induced obesity, weight loss, leptin, and genetic predisposition
- Obesity in C57BL/6J mice is characterized by adipose tissue hypoxia and cytotoxic T-cell infiltration
- Food deprivation-induced changes in body fat mobilization after neonatal monosodium glutamate treatment
- Fibroblast growth factor 21 corrects obesity in mice
- Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans
- Inflammation and adipose tissue macrophages in lipodystrophic mice
- Diacerhein improves glucose tolerance and insulin sensitivity in mice on a high-fat diet
- Probiotics improve high fat diet-induced hepatic steatosis and insulin resistance by increasing hepatic NKT cells
- Oltipraz upregulates the nuclear respiratory factor 2 alpha subunit (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a highย โฆ
- Insulin resistance, inflammation, and non-alcoholic fatty liver disease
- A highly saturated fat-rich diet is more obesogenic than diets with lower saturated fat content
- In vivo imaging of obesity-induced inflammation in adipose tissue
- Curcumin, a potential inhibitor of up-regulation of TNF-alpha and IL-6 induced by palmitate in 3T3-L1 adipocytes through NF-kappaB and JNK pathway
- Weight regain after Roux-en-Y: a significant 20% complication related to PYY
- Neural dysregulation of peripheral insulin action and blood pressure by brain endoplasmic reticulum stress
- Maternal obesity up-regulates inflammatory signaling pathways and enhances cytokine expression in the mid-gestation sheep placenta
- Voluntary exercise improves insulin sensitivity and adipose tissue inflammation in diet-induced obese mice
- High-fat diet-induced obesity in animal models
- Mechanism for improved insulin sensitivity after gastric bypass surgery
- Salsalate improves glycemia and inflammatory parameters in obese young adults
- Molecular and metabolic mechanisms of insulin resistance and ฮฒ-cell failure in type 2 diabetes
- Ciliary neurotrophic factor stimulates muscle glucose uptake by a PI3-kinaseโdependent pathway that is impaired with obesity
- Adipose tissue as an endocrine organ
- Berberine reverses free-fatty-acid-induced insulin resistance in 3T3-L1 adipocytes through targeting IKKฮฒ
- Adipose Tissue Secreted Factors in Specific Populations and Metabolic States: Implications for Energy Balance and Metabolic Health
- REIN on obesity, proteinuria and CKD
- Endoscopic solutions for weight loss
- Obesity in children. Part 2: Prevention and management
- Obesity surgery and gutโbrain communication
- Gastric bypass up-regulates insulin signaling pathway
- Hypothalamic IKKฮฒ/NF-ฮบB and ER stress link overnutrition to energy imbalance and obesity
- Angiogenesis and obesity
- Diet-induced obesity alters protein synthesis: tissue-specific effects in fasted versus fed mice
- Emerging role of adipose tissue hypoxia in obesity and insulin resistance
- 3 The Role of Obesity in
- Childhood obesity: Treatment or prevention
- Increased production of proinflammatory cytokines in adipose tissue of patients with end-stage renal disease
- Oxidative stress and inflammation as therapeutic targets for high-fat diet-induced metabolic diseases
- Bariatric surgery in young massively obese diabetic patients
- Myeloid cell-restricted insulin receptor deficiency protects against obesity-induced inflammation and systemic insulin resistance
- Inflammatory links between obesity and metabolic disease
- Inflammatory mechanisms in the regulation of insulin resistance
- Inflammatory concepts of obesity
- Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to calorie restriction and n-3 fatty acids
- Adipokines: the missing link between insulin resistance and obesity
- Insulin sensitivity: modulation by nutrients and inflammation
- Inactivation of hypothalamic FAS protects mice from diet-induced obesity and inflammation*[S]
- Dysregulation of glucocorticoid metabolism in murine obesity: comparable effects of leptin resistance and deficiency
- Obesity, adipogenesis and insulin resistance
- Maternal obesity, inflammation, and fetal skeletal muscle development
- Obesity: New Mechanisms and Translational Paradigms
- Effects of rosiglitazone on intramyocellular lipid accumulation in Psammomys obesus
- Endoscopic visceral fat removal as therapy for obesity and metabolic syndrome: a sham-controlled pilot study (with video)
- Inflammation and insulin resistance
- Tumor progression locus 2 (TPL2) regulates obesity-associated inflammation and insulin resistance
- Studies on the anti-obesity activity of zinc-ฮฑ2-glycoprotein in the rat
- Is adipose tissue metabolically different at different sites?
- Adipose tissue and ceramide biosynthesis in the pathogenesis of obesity
- PPAR ฮณ is highly expressed in F4/80hi adipose tissue macrophages and dampens adipose-tissue inflammation
- Maternal obesity promotes a proinflammatory signature in rat uterus and blastocyst
- Deficiency of angiotensin type 2 receptor rescues obesity but not hypertension induced by overexpression of angiotensinogen in adipose tissue
- n-3 PUFA: bioavailability and modulation of adipose tissue function: Symposium on ‘Frontiers in adipose tissue biology’
- Overweight, obesity, and related diseases
- Metabolic Mechanisms of Muscle Insulin Resistance
- Pigment epithelium-derived factor contributes to insulin resistance in obesity
- Chromium alleviates glucose intolerance, insulin resistance, and hepatic ER stress in obese mice
- High-fat diet: bacteria interactions promote intestinal inflammation which precedes and correlates with obesity and insulin resistance in mouse
- Obesity, inflammation, and atherosclerosis
- #VALUE!
- Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
- 45Obesity, insulin resistance and free fatty acids
- Cellular mechanisms of insulin resistance: role of stress-regulated serine kinases and insulin receptor substrates (IRS) serine phosphorylation
- Adipokines in Obesity
- TNF-ฮฑ and adipocyte biology
- Role of childhood obesity in atopic dermatitis
- Adipose tissue angiogenesis as a therapeutic target for obesity and metabolic diseases
- Regulation of energy metabolism by inflammation: a feedback response in obesity and calorie restriction
- c-Jun N-terminal kinase pathways in diabetes
- The clinical implications of blood adiponectin in cardiometabolic disorders
- Adipokine Signaling: Implications for Obesity
- EGFR tyrosine kinase inhibitor (PD153035) improves glucose tolerance and insulin action in high-fat dietโfed mice
- Food intake during the normal activity phase prevents obesity and circadian desynchrony in a rat model of night work
- Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
- Food reward, hyperphagia, and obesity
- Role of adiponectin and PBEF/visfatin as regulators of inflammation: involvement in obesity-associated diseases
- Therapeutic approaches to target inflammation in type 2 diabetes
- Evodiamine improves diet-induced obesity in a uncoupling protein-1-independent manner: involvement of antiadipogenic mechanism and extracellularly regulatedย โฆ
- Investigation of nuclear factor-ฮบB inhibitors and interleukin-10 as regulators of inflammatory signalling in human adipocytes
- Biomechanical promotion of mesenchymal stem cell proliferation as a countermeasure to the development of obesity and osteoporosis
- Maternal obesity-impaired insulin signaling in sheep and induced lipid accumulation and fibrosis in skeletal muscle of offspring
- Beneficial effects of IKKฮต-deficiency on body weight and insulin sensitivity are lost in high fat diet-induced obesity in mice
- Surgery for obesity
- Integrating Role of Adipose Tissue Secretory Functions in Response to Dietary and Pharmacological Treatments
- Pharmacological stimulation of NADH oxidation ameliorates obesity and related phenotypes in mice
- Obesity-Related Upregulation of Monocyte Chemotactic Factors in Adipocytes: Involvement of Nuclear Factor-ฮบB and c-Jun NH2-Terminal Kinase Pathways
- Tenomodulin gene and obesity-related phenotypes
- Adiponectin levels in women with polycystic ovary syndrome: impact of metformin treatment in a randomized controlled study
- Morphological and immunohistochemical features of brown adipocytes and preadipocytes in a case of human hibernoma
- Analysis of the involvement of ฮฑ2-AMPK in the beneficial effects of n-3 polyunsaturated fatty acids on obesity-associated metabolic derangements
- Effect of aspirin on the expression of hepatocyte NF-ฮบB and serum TNF-ฮฑ in streptozotocin-induced type 2 diabetic rats
- Angiogenesis and development of adipose tissue
- siRNA-mediated reduction of inhibitor of Nuclear Factor-ฮบB Kinase prevents Tumor Necrosis Factor-ฮฑโinduced insulin resistance in human skeletal muscle
- JNK1 and IKKฮฒ: molecular links between obesity and metabolic dysfunction
- Obesity in neurobiology
- Lipopolysaccharide, high glucose and saturated fatty acids induce endoplasmic reticulum stress in cultured primary human adipocytes: Salicylate alleviates this stress
- Resveratrol modulates adipokine expression and improves insulin sensitivity in adipocytes: Relative to inhibition of inflammatory responses
- Chemerin, a novel adipokine in the regulation of angiogenesis
- The Association between Obesity, Cognition, and Visual Function
- Tissular Tregs: A unique population of adipose-tissue-resident Foxp3+ CD4+ T cells that impacts organismal metabolism
- Bariatric surgery to correct morbid obesity also ameliorates atherosclerosis in patients with type 2 diabetes mellitus
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- White adipose tissue cells are recruited by experimental tumors and promote cancer progression in mouse models
- Molecular mechanisms of obesity and diabetes: at the intersection of weight regulation, inflammation, and glucose homeostasis
- Adipose inflammation: cause or consequence of obesity-related insulin resistance
- Up-regulation of Toll-like receptor 4/nuclear factor-ฮบB signaling is associated with enhanced adipogenesis and insulin resistance in fetal skeletal muscle of obeseย โฆ
- Intestinal microbiota during infancy and its implications for obesity
- B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies
- Large size cells in the visceral adipose depot predict insulin resistance in the canine model
- Cardiac lipotoxic effects of obesity
- Leptin is essential in maintaining normal vascular compliance independent of body weight
- Low birth weight and markers of inflammation and endothelial activation in adulthood: the ARIC study
- Hepatic insulin resistance, metabolic syndrome and cardiovascular disease
- Inflammatory mediators and insulin resistance in obesity: role of nuclear receptor signaling in macrophages
- Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis
- The adipocyte as an endocrine cell
- Brown adipose tissue in morbidly obese subjects
- Inhibition or deletion of the lipopolysaccharide receptor Toll-like receptor-4 confers partial protection against lipid-induced insulin resistance in rodent skeletalย โฆ
- Solidago chilensis Meyen hydroalcoholic extract reduces JNK/IฮบB pathway activation and ameliorates insulin resistance in diet-induced obesity mice
- The Role of Obesity in Insulin Resistance: Epidemiological and Metabolic Aspects
- Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
- The role of inflammatory cytokines in diabetes and its complications
- Inflammatory lipid mediators in adipocyte function and obesity
- Antioxidants preserve redox balance and inhibit c-Jun-N-terminal kinase pathway while improving insulin signaling in fat-fed rats: evidence for the role ofย โฆ
- Early insulin sensitivity after restrictive bariatric surgery, inconsistency between HOMA-IR and steady-state plasma glucose levels
- The role of oxidative stress in the pathogenesis of type 2 diabetes: from molecular mechanism to clinical implication
- Assessment of adiponectin and leptin as biomarkers of positive metabolic outcomes after lifestyle intervention in overweight and obese children
- Insulin-sensitizing effects of exercise on adiponectin and retinol-binding protein-4 concentrations in young and middle-aged women
- Insulin resistance associated to obesity: the link TNF-alpha
- Lycopene inhibits proinflammatory cytokine and chemokine expression in adipose tissue
- Nature or nurture?: focus on โPreadipocyte transplantation: an in vivo study of direct leptin signaling on adipocyte morphogenesis and cell sizeโ
- The metabolic syndrome is associated with circulating adipokines in older adults across a wide range of adiposity
- #VALUE!
- Xanthones from mangosteen prevent lipopolysaccharide-mediated inflammation and insulin resistance in primary cultures of human adipocytes
- A peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeys
- Hypoxia-inducible factor 1ฮฑ induces fibrosis and insulin resistance in white adipose tissue
- Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009
- Reduced AMP-activated protein kinase activity in mouse skeletal muscle does not exacerbate the development of insulin resistance with obesity
- Lack of interleukin-1 receptor I (IL-1RI) protects mice from high-fat dietโinduced adipose tissue inflammation coincident with improved glucose homeostasis
- Effects of systemic inflammation on insulin sensitivity in horses and inflammatory cytokine expression in adipose tissue
- The multiple facets of the fat tissue
- Lifestyle modification increases circulating adiponectin concentrations but does not change vaspin concentrations
- Determinants of brown adipocyte development and thermogenesis
- The protein kinase IKKษ regulates energy balance in obese mice
- Endoplasmic reticulum stress and inflammation in obesity and diabetes
- Aspirin attenuates insulin resistance in muscle of diet-induced obese rats by inhibiting inducible nitric oxide synthase production and S-nitrosylation of IRฮฒย โฆ
- Bofutsushosan, an oriental herbal medicine, attenuates the weight gain of white adipose tissue and the increased size of adipocytes associated with the increase inย โฆ
- Using gene expression signatures to dissect insulin resistance subtypes
- Structureโeffect relation of C18 long-chain fatty acids in the reduction of body weight in rats
- Limited weight loss or simply no weight gain following lifestyle-only intervention tends to redistribute body fat, to decrease lipid concentrations, and to improveย โฆ
- Effects of n-3 polyunsaturated fatty acids, rosiglitazone, low caloric diet and environmental pollutants: obesity and related disorders
- Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat diet
- Novel fat depotโspecific mechanisms underlie resistance to visceral obesity and inflammation in 11ฮฒ-hydroxysteroid dehydrogenase type 1โdeficient mice
- Role of heme oxygenase in inflammation, insulin-signalling, diabetes and obesity
- Type 2 diabetes as an inflammatory disease
- Luteolin inhibits inflammatory response and improves insulin sensitivity in the endothelium
- Ligand-based targeted delivery of a peptide modified nanocarrier to endothelial cells in adipose tissue
- Role of mitochondrial dysfunction in insulin resistance
- SIRT1 inhibits inflammatory pathways in macrophages and modulates insulin sensitivity
- Sodium phenylbutyrate, a drug with known capacity to reduce endoplasmic reticulum stress, partially alleviates lipid-induced insulin resistance and ฮฒ-cell dysfunctionย โฆ
- Genetic determinants and molecular pathways in the pathogenesis of Type 2 diabetes
- Anthropometric indicators of obesity and their link to lifestyle and cardiovascular risk in Colorado firefighters
- Adipokines in health and disease
- Getting the message across: mechanisms of physiological cross talk by adipose tissue
- Maternal obesity markedly increases placental fatty acid transporter expression and fetal blood triglycerides at midgestation in the ewe
- Activation of peroxisome proliferator-activated receptor-ฮด by GW501516 prevents fatty acid-induced nuclear factor-ฮบB activation and insulin resistance in skeletalย โฆ
- Metformin Improves Insulin Signaling in Obese Rats via Reduced IKK Action in a Fiber-Type Specific Manner
- Polymethoxyflavones Activate Ca2+-Dependent Apoptotic Targets in Adipocytes
- Adipose tissue development, structure and function
- Increased whole-body and sustained liver cortisol regeneration by 11ฮฒ-hydroxysteroid dehydrogenase type 1 in obese men with type 2 diabetes provides a target forย โฆ
- Uncoupling protein 1 expression and high-fat diets
- Diet-induced obesity increases NF-ฮบB signaling in reporter mice
- Increased energy expenditure contributes more to the body weight-reducing effect of rimonabant than reduced food intake in candy-fed wistar rats
- Role of substance P in the regulation of glucose metabolism via insulin signaling-associated pathways
- Vascular endothelial growth factor haplotypes associated with childhood obesity
- Regulation by chronic-mild stress of glucocorticoids, monocyte chemoattractant protein-1 and adiposity in rats fed on a high-fat diet
- Antidiabetic Properties of Zinc-ฮฑ2-Glycoprotein in ob/ob Mice
- Dissociation between skeletal muscle inhibitor-ฮบB kinase/nuclear factor-ฮบB pathway activity and insulin sensitivity in nondiabetic twins
- The effect of aspirin on atherogenic dietโinduced diabetes mellitus
- The obesity phenotype in children with asthma
- Angiogenesis associated with visceral and subcutaneous adipose tissue in severe human obesity
- Fighting fat with fat: the expanding field of adipose stem cells
- Reduction of hepatic glucocorticoid receptor and hexose-6-phosphate dehydrogenase expression ameliorates diet-induced obesity and insulin resistance inย โฆ
- Immune Modulation of Metabolism: The Role of Macrophages, NKT Cells and Dendritic Cells in the Development of the Metabolic Disturbances of Obesity
- Oxidative stress and the etiology of insulin resistance and type 2 diabetes
- Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice
- The efficiency of cellular energy transduction and its implications for obesity
- Transdifferentiation properties of adipocytes in the adipose organ
- High-fat diet induces Ikkฮฒ and reduces insulin sensitivity in rats with low running capacity
- Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment
- Central adiposity, systemic inflammation, and the metabolic syndrome
- Palmitate-induced skeletal muscle insulin resistance does not require NF-ฮบB activation
- Multi-tissue, selective PPARฮณ modulation of insulin sensitivity and metabolic pathways in obese rats
- Obesity-Associated Inflammation And Its Role In Insulin Resistance
- Impaired oxidative metabolism and inflammation are associated with insulin resistance in ERฮฑ-deficient mice
- #VALUE!
- Inflammatory biomarkers associated with obesity and insulin resistance: a focus on lipocalin-2 and adipocyte fatty acid-binding protein
- #VALUE!
- Adipose tissue-targeted 11ฮฒ-hydroxysteroid dehydrogenase type 1 inhibitor protects against diet-induced obesity
- Deficiency of haematopoietic-cell-derived IL-10 does not exacerbate high-fat-diet-induced inflammation or insulin resistance in mice
- Pathogenic perspectives for the role of inflammation in diabetic nephropathy
- IKKฮฒ suppression of TSC1 function links the mTOR pathway with insulin resistance
- Type 2 diabetes mellitus and inflammation: Prospects for biomarkers of risk and nutritional intervention
- Salsalate attenuates free fatty acidโinduced microvascular and metabolic insulin resistance in humans
- 11-Beta-hydroxysteroid dehydrogenase type 1 (11ฮฒ-HSD1) inhibitors in type 2 diabetes mellitus and obesity
- SPARC functions as an inhibitor of adipogenesis
- Cellular Remodeling during the Growth of the Adipose Tissue
- Adipose tissue macrophages: a piece of the PAI of metabolic syndrome
- Substance P (SP)-neurokinin-1 receptor (NK-1R) alters adipose tissue responses to high-fat diet and insulin action
- Inhibitory effect on protein kinase Cฮธ by Crocetin attenuates palmitate-induced insulin insensitivity in 3T3-L1 adipocytes
- In vivo and in vitro application of black soybean peptides in the amelioration of endoplasmic reticulum stress and improvement of insulin resistance
- IฮบB kinase ฮต: A potential therapeutic target for obesity (and nonalcoholic fatty liver disease)?
- Dietary bitter melon seed increases peroxisome proliferator-activated receptor-ฮณ gene expression in adipose tissue, down-regulates the nuclear factor-ฮบB expressionย โฆ
- Therapeutic prospects of metabolically active brown adipose tissue in humans
- 14 The Link Between Esophageal Cancer and Morbid Obesity
- Feed-forward signaling of TNF-ฮฑ and NF-ฮบB via IKK-ฮฒ pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
- Rescuing 3T3-L1 adipocytes from insulin resistance induced by stimulation of Akt-mammalian target of rapamycin/p70 S6 kinase (S6K1) pathway and serineย โฆ
- A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity
- Development of obesity-induced inflammation and insulin resistance: The role of adipose tissue, fatty acids, and toll-like receptors
- HSP and diabetes
- Brown fat biology and thermogenesis
- The role of the TWEAK/Fn14 signaling pathway in inflammatory and metabolic responses to diet-induced obesity
- The presence and role of brown fat in adult humans
- NATURE AND MECHANISMS OF INSULIN RESISTANCEโROLE OF ADIPOKINES IN ETIOLOGY AND PATHOGENESIS
- Transcriptional control of brown adipocyte development and physiological functionโof mice and men
- Fat Treg cells: a liaison between the immune and metabolic systems
- Peptide designed to elicit apoptosis in adipose tissue endothelium reduces food intake and body weight
- Elevated toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects
- Toll-like receptor 2 deficiency improves insulin sensitivity and hepatic insulin signalling in the mouse
- The impact of myeloid cell-restricted insulin receptor deficiency on obesity-induced insulin resistance
- Brown adipose tissue in humans is activated by elevated plasma catecholamines levels and is inversely related to central obesity
- The relationship between patients’ serum glucose levels and metabolically active brown adipose tissue detected by PET/CT
- The renin angiotensin aldosterone system in hypertension: roles of insulin resistance and oxidative stress
- THP-1 Macrophages and SGBS Adipocytes โ A New Human in vitro Model System of Inflamed Adipose Tissue
- A European evidence-based guideline for the prevention of type 2 diabetes
- The role of G-protein-coupled receptors in mediating the effect of fatty acids on inflammation and insulin sensitivity
- The cost-effectiveness of child obesity intervention
- Maternal obesity induces sustained inflammation in both fetal and offspring large intestine of sheep
- Chronic treatment with the cannabinoid 1 antagonist rimonabant altered vasoactive cyclo-oxygenase-derived products on arteries from obese Zucker rats
- Aspirin use and risk of type 2 diabetes in apparently healthy men
- Rein, tissu adipeux, adipocytesโquelles nouveautรฉs?
- Role of NF-ฮบB in the pathogenesis of diabetes and its associated complications
- Transcriptional regulation of the insulin-responsive glucose transporter GLUT4 gene: from physiology to pathology
- The peroxide dilemma: opposing and mediating insulin action
- Analysis of knockout mice suggests a role for VGF in the control of fat storage and energy expenditure
- Serum adiponectin levels are inversely correlated with insulin resistance in obese men with type 2 diabetes
- Adipose tissue: development, anatomy and functions
- Inflammation as a factor of the pathogenesis of insulin resistance and type 2 diabetes
- Exposure to a high-fat diet alters leptin sensitivity and elevates renal sympathetic nerve activity and arterial pressure in rabbits
- Visfatin and adiponectin levels in children: relationships with physical activity and metabolic parameters
- aging and Alzheimer’s disease through the biological mechanisms behind obesity and type II diabetes. May 2013 Health IN PRESS
- TLR4 and insulin resistance
- Obesity and Asthma
- Fitness level and body composition are associated with inflammation in non-obese children
- Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans
- Blockade of VEGFR2 and not VEGFR1 can limit diet-induced fat tissue expansion: role of local versus bone marrow-derived endothelial cells
- The effect of salsalate on insulin action and glucose tolerance in obese non-diabetic patients: results of a randomised double-blind placebo-controlled study
- SIRT1 exerts anti-inflammatory effects and improves insulin sensitivity in adipocytes
- SH2B1 enhances insulin sensitivity by both stimulating the insulin receptor and inhibiting tyrosine dephosphorylation of insulin receptor substrate proteins
- Homocysteine upregulates resistin production from adipocytes in vivo and in vitro
- A randomized trial of low-dose aspirin in the prevention of clinical type 2 diabetes in women
- Gene expression profiles of diabetic mice treated with whole body hyperthermia: A high-density DNA microarray analysis
- Role of the adipocyte-specific NF-ฮบB activity in the regulation of IP-10 and T cell migration
- Gut Microbes, Immunity, and Metabolism
- Adipose triacylglycerol lipase is a major regulator of hepatic lipid metabolism but not insulin sensitivity in mice
- The multi-systemic nature of diabetes mellitus: Genotype or phenotype?
- Preliminary Studies Investigating a Potential Role of an Intestinal Bacterium in the Development of Diet-Induced Obesity
- Muscle-specific IRS-1 Serโ Ala transgenic mice are protected from fat-induced insulin resistance in skeletal muscle
- 1 5 Insulin Resistance and Inhibitors of
- The Role of Adipose Tissue Vasculature in Energy Balance.
- Is there a relationship between insulin resistance and frailty syndrome?
- Kupffer cell activation is a causal factor for hepatic insulin resistance
- Gut decontamination with norfloxacin and ampicillin enhances insulin sensitivity in mice
- Lipid induced overexpression of NF-ฮบB in skeletal muscle cells is linked to insulin resistance
- Potential role of salicylates in type 2 diabetes
- Loss of Stearoyl-CoA desaturase-1 attenuates adipocyte inflammation: effects of adipocyte-derived oleate
- The implication of brown adipose tissue for humans
- To be or not to be fat: a novel role of Jak/Stat pathway in brown fat development and preventing obesity
- The Role of Fatty Acids on Toll-like Receptor 4 Regulation of Substrate Metabolism with Obesity
- The genetics of brown adipose tissue
- Long-term effect of lifestyle intervention on adiposity, metabolic parameters, inflammation and physical fitness in obese children: a randomized controlled trial
- Elevated proinflammatory cytokine production by a skewed T cell compartment requires monocytes and promotes inflammation in type 2 diabetes
- Reversible physiological transdifferentiation in the adipose organ: symposium on ‘frontiers in adipose tissue biology’
- Regulation of inducible nitric oxide synthase (iNOS) and its potential role in insulin resistance, diabetes and heart failure
- Dog obesity, dog walking, and dog health
- Effects of a structured exercise program on insulin resistance, inflammatory markers and physical fitness in obese Korean children
- Adiponectin, leptin, the adiponectin/leptin ratio, and physical fitness in children and young adults
- Endoplasmic reticulum stress-induced apoptosis in the development of diabetes: is there a role for adipose tissue and liver?
- Over-the-counter analgesics normalize blood glucose and body composition in mice fed a high fat diet
- Insulin resistance induced by tumor necrosis factor-ฮฑ in myocytes and brown adipocytes
- Salicylates increase insulin secretion in healthy obese subjects
- Aerobic training reverses high-fat diet-induced pro-inflammatory signalling in rat skeletal muscle
- Effect of the dietary fat quality on insulin sensitivity
- Fat CellโSpecific Ablation of Rictor in Mice Impairs Insulin-Regulated Fat Cell and Whole-Body Glucose and Lipid Metabolism
- Role of PPARฮณ in renoprotection in type 2 diabetes: molecular mechanisms and therapeutic potential
- High-Fat Diet: Bacteria Interactions Promote Intestinal Inflammation Which Precedes
- Modified Si-Miao-San extract inhibits inflammatory response and modulates insulin sensitivity in hepatocytes through an IKKฮฒ/IRS-1/Akt-dependent pathway
- Altered estrogen receptor expression in skeletal muscle and adipose tissue of female rats fed a high-fat diet
- Phosphorylation of IRS proteins, insulin action, and insulin resistance
- 15 Insulin Resistance and Inflammatory Signaling Pathways Modulated by High-Fat Diet
- Macrophage infiltration and cytokine release in adipose tissue: angiogenesis or inflammation?
- 2009 World Congress on the Insulin Resistance Syndrome: Cardiovascular Disease Concepts
- Adipose triglyceride lipase-null mice are resistant to high-fat dietโinduced insulin resistance despite reduced energy expenditure and ectopic lipid accumulation
- The role of ATF-2 family transcription factors in adipocyte differentiation: antiobesity effects of p38 inhibitors
- Ligands of Adipose Stem Cell Receptors Isolated by High-Throughput Combinatorial Peptide Library Screening
- 15 Insulin Resistance
- Inflammatory signaling in skeletal muscle insulin resistance: green signal for nutritional intervention?
- Activation of Fas (CD95) in adipocytes contributes to high fat diet-induced insulin-resistance
- Molecular mechanisms of insulin resistance in chronic hepatitis C
- Mathematical modeling of preadipocyte fate determination
- Sleeve gastrectomy relieves steatohepatitis in high-fat-diet-induced obese rats
- Inhibitors of 11ฮฒ-hydroxysteroid dehydrogenase type 1 in antidiabetic therapy
- Lipoic acid increases heat shock protein expression and inhibits stress kinase activation to improve insulin signaling in skeletal muscle from high-fat-fed rats
- NF-ฮบB mediates lipid-induced fetuin-A expression in hepatocytes that impairs adipocyte function effecting insulin resistance
- Macrophage-conditioned medium inhibits adipocyte differentiation
- Paradoxically high adiponectin in obese 16-year-old girls protects against appearance of the metabolic syndrome and its components seven years later
- Kaempferol and quercetin isolated from Euonymus alatus improve glucose uptake of 3T3-L1 cells without adipogenesis activity
- Downregulation of genes involved in NFฮบB activation in peripheral blood mononuclear cells after weight loss is associated with the improvement of insulinย โฆ
- Therapeutic potential of peroxisome proliferatorsโactivated receptor-ฮฑ/ฮณ dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes
- Ileal interposition improves glucose tolerance and insulin sensitivity in the obese Zucker rat
- EFFECT OF ASPIRIN PRETREATMENT IN STREPTOZOTOCINE INDUCED TYPE-II DIABETIC RATS
- Protective effect of aspirin in relation to IGF-1 in streptozotocin induced type-II diabetic rats
- Plasma adiponectin does not correlate with insulin resistance and cardiometabolic variables in nondiabetic Asian Indian teenagers
- Anti-obesity effects of resveratrol, black tea extract and caffeine in mice
- CD40L induces inflammation and adipogenesis in adipose cellsโa potential link between metabolic and cardiovascular disease
- Adipose Tissue Biology: An Update Review
- Endothelial dysfunction in diabetes mellitus: molecular mechanisms and clinical implications
- Nutrient regulation of energy metabolism in relation to obesity and type 2 diabetes
- Berberine inhibits inflammatory response and ameliorates insulin resistance in hepatocytes
- Body weight, plasma insulin, and coronary events with gemfibrozil in the Veterans Affairs High-Density Lipoprotein Intervention Trial (VA-HIT)
- The immune response attenuates growth and nutrient storage in Drosophila by reducing insulin signaling
- Effect of high-dose valsartan on inflammatory and lipid parameters in patients with Type 2 diabetes and hypertension
- Neurodegeneration in an animal model of Parkinson’s disease is exacerbated by a high-fat diet
- Reversible transdifferentiation in the adipose organ
- Differential metabolic effects in white and brown adipose tissue by conjugated linoleic acid elicit lipodystrophy-associated hepatic insulin resistance
- Targeted inactivation of MLL3 histone H3โLys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis
- #VALUE!
- Tumor necrosis factor-like weak inducer of apoptosis attenuates the action of insulin in hepatocytes
- Maternal obesity, inflammation and insulin resistance in skeletal muscle of fetal sheep
- Vitamin C inhibits leptin secretion and some glucose/lipid metabolic pathways in primary rat adipocytes
- SH2B1 regulates insulin sensitivity and glucose homeostasis by multiple mechanisms
- Insulin induced phosphorylation of prohibitin at tyrosine114 recruits Shp1
- Celecoxib attenuates liver steatosis and inflammation in non-alcoholic steatohepatitis induced by high-fat diet in rats
- Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet
- Lycopene prevents development of steatohepatitis in experimental nonalcoholic steatohepatitis model induced by high-fat diet
- Diabetes and apoptosis: liver
- Mechanisms of disease: using genetically altered mice to study concepts of type 2 diabetes
- Genetic characterization of the St. Kitts-origin vervet monkey (Chlorocebus aethiops ssp.) as a model of polygenic obesity
- A Novel Role for Fetuin-A in the Pathophysiology of Glucocorticoid-Mediated Insulin Resistance
- Impaired miR-146a expression links subclinical inflammation and insulin resistance in Type 2 diabetes
- Age and sex differences in fat distribution in non-obese Japanese children
- Role of inflammation in diabetic nephropathy
- Skeletal muscle inflammation is not responsible for the rapid impairment in adiponectin response with high-fat feeding in rats
- Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues
- Perspective: chronic obstructive pulmonary disease and obesity: more than adipose tissue mass matters
- Salsalate Efficacy in Blood Glucose Level Reduction in Diabetes
- Association of visceral adiposity with increased intrarenal artery resistive index in HIV-1-infected patients receiving highly active antiretroviral therapy
- Salicylate blocks lipolytic actions of tumor necrosis factor-ฮฑ in primary rat adipocytes
- Deposition Eliciting Insulin Resistance
- A gene expression signature for insulin resistance
- Effects of rosiglitazone and aspirin on experimental model of induced type 2 diabetes in rats: focus on insulin resistance and inflammatory markers
- Altered nuclear factor-kappaB inducing kinase expression in insulin-resistant mice
- Analysis of Main Proteins Associated with Lipid Droplets from Peri-Adrenal Adipose Tissue of Patients with Cushing’s Syndrome
- #VALUE!
- Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes
- A central role for hepatocyte growth factor in adipose tissue angiogenesis
- Antiobesity effect of allenic carotenoid, fucoxanthin
- Transcriptional Control of Gene Expression in Different Adipose Tissue Depots
- Local activation of the IฮบK-NF-ฮบB pathway in muscle does not cause insulin resistance
- Identification of a novel peptide ligand targeting visceral adipose tissue via transdermal route by in vivo phage display
- LOX-1, oxidative stress and inflammation: a novel mechanism for diabetic cardiovascular complications
- The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial
- IFATS collection: Combinatorial peptides identify ฮฑ5ฮฒ1 integrin as a receptor for the matricellular protein SPARC on adipose stromal cells
- Reactive oxygen species production is increased in the peripheral blood monocytes of obese patients
- Extracellular high dosages of adenosine triphosphate induce inflammatory response and insulin resistance in rat adipocytes
- Role of inhibitory ฮบB kinase and c-Jun NH2-terminal kinase in the development of hepatic insulin resistance in critical illness diabetes
- Role of inflammation and endothelial dysfunction of coronary arterioles in type 2 diabetes
- Role of reactive oxygen species in the progression of type 2 diabetes and atherosclerosis
- Involvement of inducible nitric oxide synthase in hydroxyl radical-mediated lipid peroxidation in streptozotocin-induced diabetes
- Genetic Analysis of Adipose Lineage and Development
- Stakeholder perceptions of the CHANGES weight management service
- Prenatal hypoxia independent of undernutrition promotes molecular markers of insulin resistance in adult offspring
- Bifurcation of in vivo hepatic energy metabolism and glucose production in insulin resistance and diabetes
- Inhibition of the Nuclear Factor-ฮบB Pathway Prevents Beta Cell Failure and Diet Induced Diabetes in Psammomys obesus
- The emergence of cold-induced brown adipocytes in mouse white fat depots is determined predominantly by white to brown adipocyte transdifferentiation
- Fish oil rich diet in comparison to saturated fat rich diet offered protection against lipopolysaccharide-induced inflammation and insulin resistance in mice
- Link between plasma ceramides, inflammation and insulin resistance: association with serum IL-6 concentration in patients with coronary heart disease
- Insulin Resistance and Inhibitors of the Insulin Receptor Tyrosine Kinase
- Enhanced glycogen metabolism in adipose tissue decreases triglyceride mobilization
- Lessons in initiating insulin in clinical practice
- An isoform of decorin is a resistin receptor on the surface of adipose progenitor cells
- Effects of exercise training and diet on lipid kinetics during free fatty acid-induced insulin resistance in older obese humans with impaired glucose tolerance
- Reduction of hepatic CEACAM1 levels: an early mechanism of insulin resistance induced by high-fat diet
- A new era for brown adipose tissue: New insights into brown adipocyte function and differentiation
- Activation of Inflammatory pathways impairs insulin signaling in obese Zucker rat skeletal muscle
- Metabolic Characterization of Human FOXC2 in Adipose Tissue
- Studies examining the function of adipose tissue macrophages
- Exercise and Type 2 Diabetes in Youth
- Osteopontin knockout abates high fat diet-induced insulin resistance and adipose tissue inflammation
- Aspirin and diabetes mellitus: revisiting an old player
- High-fat feeding increases insulin receptor and IRS-1 coimmunoprecipitation with SOCS-3, IKKฮฑ/ฮฒ phosphorylation and decreases PI-3 kinase activity in muscle
- Specificity of insulin signalling in human skeletal muscle as revealed by small interfering RNA
- #VALUE!
- Methodological and Clinical Studies on Insulin Resistance in Childhood
- ฮฒ3-Adrenergic Signaling Acutely Down Regulates Adipose Triglyceride Lipase in Brown Adipocytes
- Effect of the dietary fat quality on insulin sensitivity
- Therapeutic Strategies for the Treatment of Insulin Resistance in Various Metabolic Disease States
- 15 Exercise and Type 2 Diabetes in Youth
- Aryl hydrocarbon receptor deficiency enhances insulin sensitivity and reduces PPAR-ฮฑ pathway activity in mice
- Evidence for increased risk of prediabetes in the uremic patient
- Biochemical Evaluation of Serum Adiponectin Level in Egyptian Breast Cancer Patients before and after Treatment
- NF-ฮบB activity in muscle from obese and type 2 diabetic subjects under basal and exercise-stimulated conditions
- Leucine-induced Impairment of Insulin Sensitivity in Skeletal Muscle of Healthy Rats is Reversible
- New Trends of Diabetes Therapy type II of the Animal Model
- Objectively measured physical activity is negatively associated with plasma adiponectin levels in minority female youth
- #VALUE!
- Salicylates increase insulin secretion in healthy obese
- Chronically Elevated Glucocorticoids in Conjunction with a High Fat Diet: A Model of Non Alcoholic Fatty Liver Disease
- Molecular mechanisms of hepatic insulin resistance following injury
- Distinct functions of autophagy kinases ULK1 and ULK2 in adipogenesis and adipocyte metabolism
- Sweet heartโcontributions of metabolism in the development of heart failure in diabetes mellitus
- Chronic inflammation in the metabolic syndrome: emphasis on adipose tissue
- Temporal Mechanisms by which a High Fat-diet Induces Skeletal Muscle Insulin Resistance
- Insulin action
- Oxidative stress in type 2 diabetes mellitus
- The effect of high-dose sodium salicylate on chronically elevated plasma nonesterified fatty acid-induced insulin resistance and ฮฒ-cell dysfunction in overweight andย โฆ
- Role of the IKKฮฒ/NF-ฮบB inflammatory pathway, free fatty acids, and adiposity in insulin resistance in Hispanic Americans
- Diabetes mellitus: metabolic effects and oxidative stress
- Inflammation and NF-ฮบB in Alzheimer’s disease and diabetes
- Regulation of PGC-1 alpha in white adipose tissue by exercise
- 100 questions & answers about diabetes
- Fatty acid-induced NF-ฮบB activation and insulin resistance in skeletal muscle are chain length dependent
- Association of the polymorphisms in the PSMA6 (rs1048990) and PSMB5 (rs2230087) genes with type 2 diabetes in Korean subjects
- Overexpression of liver-specific cytochrome P4502E1 impairs hepatic insulin signaling in a transgenic mouse model of nonalcoholic fatty liver disease
- Diabetic cardiomyopathy-to take a long story serious
- Role of altered insulin signaling pathways in the pathogenesis of podocyte malfunction and microalbuminuria
- Interscapular brown adipose tissue metabolic reprogramming during cold acclimation: Interplay of HIF-1ฮฑ and AMPKฮฑ
- The effect of aspirin (ASA) given in cardiovascular therapeutic doses on glycemic control in type II diabetes
- Proteomic Study of the Effect ofBerberine on the Adipose Tissue ofdb/db Mice and 3T3-L1 Adipocytes
- The Relationship Between the Insulin Receptor Substrates and Metabolic Disease
- Important genetic checkpoints for insulin resistance in salt-sensitive (S) Dahl rats
- Aspirin reduces hypertriglyceridemia by lowering VLDL-triglyceride production in mice fed a high-fat diet
- A study of non-alcoholic fatty liver disease (NAFLD) in South African patients and analysis of candidate genes in insulin resistance and fatty acid oxidation.
- Elucidation of mechanisms of insulin resistance in human skeletal muscle
- Molecular aspects of genetic predisposition to type 2 diabetes mellitus and its monogenic forms
- Transcriptional responses of insulin resistance and mechanisms of drug action
- Saturated fatty acid-induced NF-ฮบB activation and insulin resistance in skeletal muscle are chain length dependent
- Pro-inflammatory cytokines in Omani type 2 diabetic patients presenting anxiety and depression
- Genetic predisposition to diabetic nephropathy
- A population of multipotent CD34-positive adipose stromal cells share pericyte and mesenchymal surface markers, reside in a periendothelial location, and stabilizeย โฆ
- Diabetische Kardiomyopathieโeine lang wรคhrende und ernstzunehmende Erkrankung
- Regulation of Insulin and CHOP Gene Expression in Pancreatic Beta Cells
- DOES ASPIRIN PRETREATMENT PREVENT DIABETES IN RATS?
- Effect of early insulin therapy on nuclear factor ฮบB and cytokine gene expressions in the liver and skeletal muscle of high-fat diet, streptozotocin-treated diabetic rats
- Depot-Specific Gene Expression Programs of Adipocytes: Physiological and Developmental Implications
- Global IRS-1 phosphorylation analysis in insulin resistance
- The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
- The diabetogenic effects of excessive ethanol: reducing ฮฒ-cell mass, decreasing phosphatidylinositol 3-kinase activity and GLUT-4 expression in rats
- The unsolved problem of diabetes mellitus type 2 and associated complications
- ฮฒ-Arrestins: multifunctional signaling adaptors in type 2 diabetes
- Insulin Action in Peripheral Glucose Uptake-The Molecular Perspective
- Pilot randomized trial demonstrating reversal of obesity-related abnormalities in reward system responsivity to food cues with a behavioral intervention
- Reversal of obesity-induced hypertriglyceridemia by (R)-ฮฑ-lipoic acid in ZDF (fa/fa) rats
- Partial reversal of obesity-induced insulin resistance owing to anti-inflammatory immunomodulatory potential of flaxseed oil
- Brown adipose tissue thermogenesis in the resistance to and reversal of obesity: a potential new mechanism contributing to the metabolic benefits of proglucagonย โฆ
- Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models
- Dietary restriction reverses obesity-induced anhedonia
- Reversal of obesity and metabolic disorders by exercise in high-fat diet-induced obese c57bl/6 mice
- New pharmacological perspectives for the leptin receptor in the treatment of obesity
- Metabolic Effects of n-3 PUFA as Phospholipids Are Superior to Triglycerides in Mice Fed a High-Fat Diet: Possible Role of Endocannabinoids
- Animal models of dietary-induced obesity
- IL-33 reverses an obesity-induced deficit in visceral adipose tissue ST2+ T regulatory cells and ameliorates adipose tissue inflammation and insulin resistance
- Weight loss reversed obesity-induced HGF/c-Met pathway and basal-like breast cancer progression
- Steps to Growing Up Healthy: a pediatric primary care based obesity prevention program for young children
- Inhalation of carbon monoxide is ineffective as a long-term therapy to reduce obesity in mice fed a high fat diet
- Role of obesity and lipotoxicity in the development of nonalcoholic steatohepatitis: pathophysiology and clinical implications
- Hypothalamic gliosis associated with high-fat diet feeding is reversible in mice: a combined immunohistochemical and magnetic resonance imaging study
- The adipose organ of obesity-prone C57BL/6J mice is composed of mixed white and brown adipocytes
- A comparative study between nanoparticle-targeted therapeutics and bioconjugates as obesity medication
- ATRIAL FIBRILLATION AND OBESITY: CHARACTERIZATION OF ELECTRO-STRUCTURAL ATRIAL SUBSTRATE WITH SUSTAINED OBESITY ANDย โฆ
- Exercise treatment of obesity
- Chronic Treatment with Carbon Monoxide Releasing Molecule Reverses Dietary Induced Obesity in Mice
- Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity
- Atrial fibrillation and obesity: characterization of electro-structural atrial substrate with sustained obesity and reversal upon weight reduction.
- Therapeutic assessment of cytochrome C for the prevention of obesity through endothelial cell-targeted nanoparticulate system
- Role of obesity in the pathogenesis and progression of Barrett’s esophagus
- Recombinant murine fibroblast growth factor 21 ameliorates obesity-related inflammation in monosodium glutamate-induced obesity rats
- Cellular and molecular players in adipose tissue inflammation in the development of obesity-induced insulin resistance
- Resveratrol inhibits the deleterious effects of diet-induced obesity on thymic function
- From abject eating to abject being: Representations of obesity in ‘Supersize vs. Superskinny’
- Enhancement of brown fat thermogenesis using chenodeoxycholic acid in mice
- Hepatic cannabinoidโ1 receptors mediate dietโinduced insulin resistance by increasing de novo synthesis of longโchain ceramides
- Short-term supplementation with a specific combination of dietary polyphenols increases energy expenditure and alters substrate metabolism in overweight subjects
- Pathophysiology of obesity-related renal dysfunction contributes to diabetic nephropathy
- Abstract IA45: Obesity and the microenvironment in basal-like breast cancer
- Physical exercise in overweight to obese individuals induces metabolic-and neurotrophic-related structural brain plasticity
- Social Aspects as Maintenance Factors of the Obesity Condition: The Somatic Marker Hypothesis
- Caffeic acid phenethyl ester reduces the activation of the nuclear factor ฮบB pathway by high-fat diet-induced obesity in mice
- Glutamate mediates the function of melanocortin receptor 4 on Sim1 neurons in body weight regulation
- APpEaLINg therapeutic target for obesity cardiomyopathy?
- Animal Models for the Study of Human Disease: Chapter 13. Animal Models of Dietary-Induced Obesity
- Immune regulation in obesity-associated adipose inflammation
- The impact of cash transfers to poor women in Colombia on BMI and obesity: prospective cohort study
- Prognosis of morbid obesity patients with advanced heart failure
- Two contrasting outcomes of weight loss surgery: Positive impact on the heart, negative impact on the liver
- DIEtAry CONtrOL Of OBESIty AND LAMINItIS rISk
- Healthy Alberta Communities: Impact of a three-year community-based obesity and chronic disease prevention intervention
- Leptin, a mediator of cardiac damage associated with obesity
- Inflammation as a link between obesity, metabolic syndrome and type 2 diabetes
- Role of Adiponectin in the Metabolic Effects of Cannabinoid Receptor-1 Blockade in Mice with Diet-Induced Obesity
- Measuring success: a comparison of weight loss calculations
- #VALUE!
- Treatment of obesity as a potential complementary approach to cancer therapy
- Sustained activation of PPARฮฑ by endogenous ligands increases hepatic fatty acid oxidation and prevents obesity in ob/ob mice
- Browning of white adipose tissue by melatonin
- A review on obesity and its management
- Effects of an intensive short-term diet and exercise intervention: comparison between normal-weight and obese children
- Endospanin 1 silencing in the hypothalamic arcuate nucleus contributes to sustained weight loss of high fat diet obese mice
- Cytokine profiling of young overweight and obese female African American adults with prediabetes
- A neuron-specific deletion of the microRNA-processing enzyme DICER induces severe but transient obesity in mice
- Chaperoning to the metabolic party: the emerging therapeutic role of heat-shock proteins in obesity and type 2 diabetes
- Subcutaneous adipose tissue transplantation in dietโinduced obese mice attenuates metabolic dysregulation while removal exacerbates it
- Cichoric acid reverses insulin resistance and suppresses inflammatory responses in the glucosamine-induced HepG2 cells
- Obesity, systemic inflammation, and increased risk for cardiovascular disease and diabetes among adolescents: a need for screening tools to target interventions
- Curcumin promotes browning of white adipose tissue in a norepinephrine-dependent way
- The complex and multifactorial relationship between testosterone deficiency (TD), obesity and vascular disease
- Polysome profiling in liver identifies dynamic regulation of endoplasmic reticulum translatome by obesity and fasting
- Effects of metformin on weight loss: potential mechanisms
- The neuropathology of obesity: insights from human disease
- A role for sphingolipids in the pathophysiology of obesity-induced inflammation
- Role of interleukins in obesity: implications for metabolic disease
- Cardioprotective modulation of cardiac adiponectin and adiponectin receptors by omega-3 in the high-fat fed rats
- #VALUE!
- Influence of circular stapler diameter on postoperative stenosis after laparoscopic gastrojejunal anastomosis in morbid obesity
- Insulin inhibits IL-10โmediated regulatory T cell function: implications for obesity
- Prevention of Diet-Induced Obesity Effects on Body Weight and Gut Microbiota in Mice Treated Chronically with ฮ9-Tetrahydrocannabinol
- Diabetes and cancer: placing the association in perspective
- Hypothalamic endoplasmic reticulum stress and insulin resistance in offspring of mice dams fed high-fat diet during pregnancy and lactation
- Obesity and cholangiocarcinoma
- The adipose organ at a glance
- Pregnancy is a critical period for prevention of obesity and cardiometabolic risk
- Insulin resistance and impaired adipogenesis
- The brown fat secretome: metabolic functions beyond thermogenesis
- Sex differences during the course of diet-induced obesity in mice: adipose tissue expandability and glycemic control
- HealthSTEPS: An Evidence-Based Program to Prevent Obesity and Related Diseases in Young Children
- Adipose tissue inflammation in the pathogenesis of type 2 diabetes
- Vascular-targeted nanotherapy for obesity: unexpected passive targeting mechanism to obese fat for the enhancement of active drug delivery
- Mechanisms of obesity-induced inflammation and insulin resistance: insights into the emerging role of nutritional strategies
- Effects of voluntary running on oxygen consumption, RQ, and energy expenditure during primary prevention of diet-induced obesity in C57BL/6N mice
- Obesity and Weight Regulation
- The bright-nights and dim-days of the urban photoperiod: implications for circadian rhythmicity, metabolism and obesity
- Obesity, a health burden of a global nature
- Physiotherapists’ perceptions of their role in the rehabilitation management of individuals with obesity
- Fat cells directly sense temperature to activate thermogenesis
- Mechanisms of insulin resistance in obesity
- Vitamin C in the treatment and/or prevention of obesity
- Inflammation-induced microvascular insulin resistance is an early event in diet-induced obesity
- Metabolic heterogeneity of obesity: role of adipose tissue
- Does chronic low-grade endotoxemia define susceptibility of obese humans to insulin resistance via dietary effects on gut microbiota?
- Distinct roles for JNK and IKK activation in agouti-related peptide neurons in the development of obesity and insulin resistance
- Inflammation produces catecholamine resistance in obesity via activation of PDE3B by the protein kinases IKKฮต and TBK1
- Role of T cells in malnutrition and obesity
- Causes and consequences of obesity: the contribution of recent twin studies
- Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity
- Constitutive activation of IKKฮฒ in adipose tissue prevents diet-induced obesity in mice
- TRPV4 is a regulator of adipose oxidative metabolism, inflammation, and energy homeostasis
- Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer’s disease
- Maternal hyperglycemia during pregnancy predicts adiposity of the offspring
- A high ratio of dietary n-3/n-6 polyunsaturated fatty acids improves obesity-linked inflammation and insulin resistance through suppressing activation of TLR4 in SDย โฆ
- Bariatric surgery-effects on obesity and related co-morbidities
- Decreased circulating levels of oxytocin in obesity and newly diagnosed type 2 diabetic patients
- Human brown adipose tissue: what we have learned so far
- Impact of abdominal obesity and ambulatory blood pressure in the diagnosis of left ventricular hypertrophy in never treated hypertensives
- Age and obesity promote methylation and suppression of 5ฮฑ-reductase 2: implications for personalized therapy of benign prostatic hyperplasia
- Fibroblast growth factor-21 protects human skeletal muscle myotubes from palmitate-induced insulin resistance by inhibiting stress kinase and NF-ฮบB
- Oncostatin M is a potential agent for the treatment of obesity and related metabolic disorders: a study in mice
- Mechanisms in endocrinology: white, brown and pink adipocytes: the extraordinary plasticity of the adipose organ
- Oxidative stress and inflammation interactions in human obesity
- High-fat load: mechanism (s) of insulin resistance in skeletal muscle
- Recruitment of brown adipose tissue as a therapy for obesity-associated diseases
- Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development
- Metabolic inflammation: connecting obesity and insulin resistance
- High-Fat Diet-Induced Obesity Exacerbates Inflammatory Bowel Disease in Genetically Susceptible Mdr1aโ/โ Male Mice
- The impact of generation status on weight of immigrant and non-immigrant school-aged children living in minority situation: Preliminary results
- Autophagy regulates inflammation in adipocytes
- Populus balsamifera L.(Salicaceae) mitigates the development of obesity and improves insulin sensitivity in a diet-induced obese mouse model
- Doxorubicin treatment inhibits PPARฮณ and may induce lipotoxicity by mimicking a type 2 diabetes-like condition in rodent models
- From farm to fat cell: why aren’t we all fat?
- Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice
- The combined effects of physical exercise training and detraining on adiponectin in overweight and obese children
- The effect of exercise training in water on serum adiponectin and insulin resistance in obese children and adolescents
- Obesity as a risk and severity factor in rheumatic diseases (autoimmune chronic inflammatory diseases)
- Methods of a Multidisciplinary, Community-based Treatment Program for Overweight and Obese Preschoolers: A Family-Oriented, Healthy Eating, Activity, andย โฆ
- Bacteria, viruses, and hypothalamic inflammation: Potential new players in obesity
- Free Fatty Acids Induce Lhb mRNA but Suppress Fshb mRNA in Pituitary LฮฒT2 Gonadotropes and Diet-Induced Obesity Reduces FSH Levels in Male Mice andย โฆ
- Insulin and IGFs in obesity-related breast cancer
- Recent advances in obesity-induced inflammation and insulin resistance
- Targeting the IKKฮฒ/mTOR/VEGF signaling pathway as a potential therapeutic strategy for obesity-related breast cancer
- Dichotomous effects of VEGF-A on adipose tissue dysfunction
- Inflammation during obesity is not all bad: evidence from animal and human studies
- Longitudinal assessment of food intake, fecal energy loss, and energy expenditure after Roux-en-Y gastric bypass surgery in high-fat-fed obese rats
- Endocrine changes in obesity
- Peripheral targets in obesity treatment: a comprehensive update
- Adipose tissue-related proteins locally associated with resolution of inflammation in obese mice
- Overexpression of endothelial nitric oxide synthase prevents diet-induced obesity and regulates adipocyte phenotype
- Effectiveness of lifestyle interventions in child obesity: systematic review with meta-analysis
- The By-Band study: gastric bypass or adjustable gastric band surgery to treat morbid obesity: study protocol for a multi-centre randomised controlled trial withย โฆ
- Impact of wheat aleurone structure on metabolic disorders caused by a high-fat diet in mice
- Obesity alters the gustatory perception of lipids in the mouse: plausible involvement of lingual CD36
- White-to-brown transdifferentiation of omental adipocytes in patients affected by pheochromocytoma
- Obesity, but not ethanol, promotes tumor incidence and progression in a mouse model of hepatocellular carcinoma in vivo
- Implication of inflammatory signaling pathways in obesity-induced insulin resistance
- Aryl hydrocarbon receptor deficiency protects mice from diet-induced adiposity and metabolic disorders through increased energy expenditure
- The endoplasmic reticulum stress marker, glucose-regulated protein-78 (GRP78) in visceral adipocytes predicts endometrial cancer progression and patient survival
- #VALUE!
- Stromal progenitor cells from endogenous adipose tissue contribute to pericytes and adipocytes that populate the tumor microenvironment
- BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response
- The role of specific chaperons in pathogenesis of obesity and related diseases
- Fas (CD 95) expression in myeloid cells promotes obesityโinduced muscle insulin resistance
- Influence of the core circadian gene โClockโ on obesity and leptin resistance in mice
- Function and control of adipose tissue regulatory T cells: implications for obesity
- Antiangiogenic nanotherapy for the control of obesity
- Updates on gastric electrical stimulation to treat obesity: Systematic review and future perspectives
- Protein tyrosine phosphatase 1B (PTP1B) and obesity
- Salicylate downregulates 11ฮฒ-HSD1 expression in adipose tissue in obese mice and in humans, mediating insulin sensitization
- Inflammation, cytokines and insulin resistance: a clinical perspective
- IKKฮฒ links vascular inflammation to obesity and atherosclerosis
- A ceramide-centric view of insulin resistance
- Placental dysfunction in obese women and antenatal surveillance strategies
- Double-stranded RNA-activated protein kinase is a key modulator of insulin sensitivity in physiological conditions and in obesity in mice
- The whitening of brown fat and its implications for weight management in obesity
- Role of saturated and polyunsaturated fat in obesity-related inflammation
- Surgery for weight loss in adults
- Leptin-mediated increases in catecholamine signaling reduce adipose tissue inflammation via activation of macrophage HDAC4
- A platelet-activating factor (PAF) receptor deficiency exacerbates diet-induced obesity but PAF/PAF receptor signaling does not contribute to the development ofย โฆ
- Obesity, insulin resistance, and inflammaging
- The beta-3 adrenergic agonist (CL-316,243) restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice
- Vascular rarefaction mediates whitening of brown fat in obesity
- Does inflammation determine whether obesity is metabolically healthy or unhealthy? The aging perspective
- Genetics and obesity
- Two triterpeniods from Cyclocarya paliurus (Batal) Iljinsk (Juglandaceae) promote glucose uptake in 3T3-L1 adipocytes: The relationship to AMPK activation
- Appetite and body weight regulation after bariatric surgery
- White-to-brown metabolic conversion of human adipocytes by JAK inhibition
- Connecting type 1 and type 2 diabetes through innate immunity
- Intranasal insulin therapy for cognitive impairment and neurodegeneration: current state of the art
- Presence of brown adipocytes in retroperitoneal fat from patients with benign adrenal tumors: relationship with outdoor temperature
- Macrophage HIF-2ฮฑ ameliorates adipose tissue inflammation and insulin resistance in obesity
- Adipose tissue immunity and cancer
- Avatars of Adipose TissueโThe Saga of Transformation of White Fat, the Villain into 3 Brown Fat, the Protector 4
- Distinct time course of the decrease in hepatic AMP-activated protein kinase and Akt phosphorylation in mice fed a high fat diet
- Reversion to a control balanced diet is able to restore body weight and to recover altered metabolic parameters in adult rats long-term fed on a cafeteria diet
- Apparent histological changes of adipocytes after treatment with CL 316,243, a ฮฒ-3-adrenergic receptor agonist
- Inflammatory causes of obesity and metabolic diseases
- Insulin sensitization via partial agonism of PPARฮณ and glucose uptake through translocation and activation of GLUT4 in PI3K/p-Akt signaling pathway by embelin inย โฆ
- Blockade of the nuclear factor-ฮบB pathway in the endothelium prevents insulin resistance and prolongs life spans
- Weighing in on adipocyte precursors
- Sphingolipid metabolism and obesity-induced inflammation
- Role of ฮฒ-adrenergic receptors in the anti-obesity and anti-diabetic effects of zinc-ฮฑ2-glycoprotien (ZAG)
- Diabetes mellitus in dogs and its associated complications: A review
- Obesity, inflammation, and insulin resistance
- The adipose organ: whiteโbrown adipocyte plasticity and metabolic inflammation
- Berberine activates thermogenesis in white and brown adipose tissue
- Leucine signaling in the pathogenesis of type 2 diabetes and obesity
- Effect of obesity on hepatic drug metabolism
- Role of oxidative stress in endothelial insulin resistance
- Zinc deficiency augments leptin production and exacerbates macrophage infiltration into adipose tissue in mice fed a high-fat diet
- TGF-ฮฒ/Smad3 signaling regulates brown adipocyte induction in white adipose tissue
- B lymphocytes as emerging mediators of insulin resistance
- Prospects of use of nutrient fiber, applying different feeding manners, to reduce obesity in dogs.
- Central inflammation and leptin resistance are attenuated by ginsenoside Rb1 treatment in obese mice fed a high-fat diet
- Mineralocorticoid receptor antagonism induces browning of white adipose tissue through impairment of autophagy and prevents adipocyte dysfunction in highโfatโdietย โฆ
- Increased adipose tissue hypoxia and capacity for angiogenesis and inflammation in young diet-sensitive C57 mice compared with diet-resistant FVB mice
- 4ฮฒ-Hydroxywithanolide E isolated from Physalis pruinosa calyx decreases inflammatory responses by inhibiting the NF-ฮบB signaling in diabetic mouse adipose tissue
- A2B Adenosine Receptors Prevent Insulin Resistance by Inhibiting Adipose Tissue Inflammation via Maintaining Alternative Macrophage Activation
- Flurbiprofen ameliorated obesity by attenuating leptin resistance induced by endoplasmic reticulum stress
- Hypothalamic gene transfer of BDNF inhibits breast cancer progression and metastasis in middle age obese mice
- MicroRNA-133 controls brown adipose determination in skeletal muscle satellite cells by targeting Prdm16
- Vascular Targeting of Adipose Tissue
- Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronaryย โฆ
- Pleiotropic actions of insulin resistance and inflammation in metabolic homeostasis
- Omega-3 phospholipids from fish suppress hepatic steatosis by integrated inhibition of biosynthetic pathways in dietary obese mice
- Global correlation analysis for microRNA and gene expression profiles in human obesity
- Gene silencing in adipose tissue macrophages regulates whole-body metabolism in obese mice
- Fibrosis and adipose tissue dysfunction
- Acute pancreatitis due to diabetes: the role of hyperglycaemia and insulin resistance
- Targeted delivery using peptide-functionalised gold nanoparticles to white adipose tissues of obese rats
- The regulation of muscle protein turnover in diabetes
- Role of the adipocyte in metabolism and endocrine function
- Brown adipose tissue: what have we learned since its recent identification in human adults
- Endocrine and metabolic signaling in retroperitoneal white adipose tissue remodeling during cold acclimation
- PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway
- Effects of an in-patient treatment program based on regular exercise and a balanced diet on high molecular weight adiponectin, resistin levels, and insulin resistanceย โฆ
- Local macrophage proliferation in adipose tissue is a characteristic of obesity-associated inflammation: A dissertation
- Food cue reactivity, obesity, and impulsivity: are they associated?
- Niclosamide ethanolamineโinduced mild mitochondrial uncoupling improves diabetic symptoms in mice
- (โ)-Epicatechin mitigates high-fructose-associated insulin resistance by modulating redox signaling and endoplasmic reticulum stress
- NF-ฮบBโinducing kinase (NIK) promotes hyperglycemia and glucose intolerance in obesity by augmenting glucagon action
- Adipocytokines in relation to cardiovascular disease
- Metabolic adaptation of white adipose tissue to nutritional and environmental challenges
- Opposite cross-talk by oleate and palmitate on insulin signaling in hepatocytes through macrophage activation
- Rapid and weight-independent improvement of glucose tolerance induced by a peptide designed to elicit apoptosis in adipose tissue endothelium
- Anti-inflammatory agents to treat or prevent type 2 diabetes, metabolic syndrome and cardiovascular disease
- The role of chronic inflammation in obesity-associated cancers
- Stromal cells derived from visceral and obese adipose tissue promote growth of ovarian cancers
- Gallic acid attenuates high-fat diet fed-streptozotocin-induced insulin resistance via partial agonism of PPARฮณ in experimental type 2 diabetic rats and enhancesย โฆ
- Celecoxib ameliorates non-alcoholic steatohepatitis in type 2 diabetic rats via suppression of the non-canonical Wnt signaling pathway expression
- Brown and Beige Fat: Therapeutic Potential in Obesity
- Oligopeptide complex for targeted non-viral gene delivery to adipocytes
- Emerging role of JNK in insulin resistance
- C5aR and C3aR antagonists each inhibit dietโinduced obesity, metabolic dysfunction, and adipocyte and macrophage signaling
- Adipokines and cardiovascular risk in Cushing’s syndrome
- Insulin resistance and atherosclerosis
- Role of NKG2D in obesity-induced adipose tissue inflammation and insulin resistance
- CD40 deficiency in mice exacerbates obesity-induced adipose tissue inflammation, hepatic steatosis, and insulin resistance
- Type 2 Diabetes: Disease Overview
- Circulating levels of IL-1B+ IL-6 cause ER stress and dysfunction in islets from prediabetic male mice
- GLP-1 based therapeutics: simultaneously combating T2DM and obesity
- Novel risk factors of cardiovascular disease and their associations between obesity, physical activity and physical fitness
- Herbal and microbial products for the management of obesity
- Adiponectin, resistin, and visfatin in childhood obesity and exercise
- Nuclear factor ฮบBโinducing kinase activation as a mechanism of pancreatic ฮฒ cell failure in obesity
- Insulin resistance
- Development of an innovative drug delivery system targeted to adipose vessel utilizing novel nucleic acid aptamer for control of obesity
- p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells
- #VALUE!
- TGF-B/Smad3 signaling regulates brown adipocyte induction in white adipose tissue
- Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity
- Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure
- Lipid-overloaded enlarged adipocytes provoke insulin resistance independent of inflammation
- Reduction of insulin resistance and plasma glucose level by salsalate treatment in persons with prediabetes
- Role of nuclear factor (erythroid-derived 2)-like 2 in metabolic homeostasis and insulin action: a novel opportunity for diabetes treatment?
- The lipocalin-type prostaglandin D2 synthase knockout mouse model of insulin resistance and obesity demonstrates early hypothalamic-pituitary-adrenal axisย โฆ
- Metabolic inflexibility of white and brown adipose tissues in abnormal fatty acid partitioning of type 2 diabetes
- Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by ฮฒ3-Adrenergic Agonist: A Role for MicroRNAs
- Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance
- The expression of genes involved in NF-ฮบB activation in peripheral blood mononuclear cells of patients with gestational diabetes
- Obesity-related glomerulopathy and podocyte injury: a mini review
- Metabolic syndrome, insulin resistance, and roles of inflammationโmechanisms and therapeutic targets
- Molecular imaging of brown adipose tissue in health and disease
- Ciliary neurotrophic factor (CNTF) protects non-obese Swiss mice against type 2 diabetes by increasing beta cell mass and reducing insulin clearance
- Both linoleic and ฮฑ-linolenic acid prevent insulin resistance but have divergent impacts on skeletal muscle mitochondrial bioenergetics in obese Zucker rats
- Adipokine inflammation and insulin resistance: the role of glucose, lipids and endotoxin
- Mechanisms of disease: role of neurotrophins in diabetes and diabetic neuropathy
- Salsalate and adiponectin improve palmitate-induced insulin resistance via inhibition of selenoprotein P through the AMPK-FOXO1ฮฑ pathway
- Glucagon-like peptide 1 regulates adipogenesis in 3T3-L1 preadipocytes
- Physical inactivity, insulin resistance, and the oxidative-inflammatory loop
- Why does obesity increase the risk for cardiovascular disease?
- Association of ALOX15 gene polymorphisms with obesity-related phenotypes in Chinese nuclear families with male offspring
- Inflammatory markers in pediatric obesity: health and physical activity implications
- FGF21 regulates PGC-1ฮฑ and browning of white adipose tissues in adaptive thermogenesis
- CEACAM1 loss links inflammation to insulin resistance in obesity and non-alcoholic steatohepatitis (NASH)
- Identification of nuclear hormone receptor pathways causing insulin resistance by transcriptional and epigenomic analysis
- Age impact on weight loss and glycolipid profile after laparoscopic sleeve gastrectomy: experience with 308 consecutive patients
- Berries in Prevention of Metabolic Diseaseโfocus on obesity, diabetes and gut microbiota
- Astragalus Polysaccharide Improves Palmitate-Induced Insulin Resistance by Inhibiting PTP1B and NF-ฮบB in C2C12 Myotubes
- Obesity & the Workplace: Direct, Indirect Costs & the Role of Wellness Education
- Inhibiting adipose tissue lipogenesis reprograms thermogenesis and PPARฮณ activation to decrease diet-induced obesity
- Influence of vitamin D treatment on transcriptional regulation of insulin-sensitive genes
- Proteomic identification of target proteins of thiodigalactoside in white adipose tissue from diet-induced obese rats
- Resveratrol prevents insulin resistance caused by short-term elevation of free fatty acids in vivo
- Serum cytokine, chemokine and hormone levels in Saudi adults with pre-diabetes: a one-year prospective study
- Oxidative stress in diabetes
- Neural innervation of white adipose tissue and the control of lipolysis
- Role of adipose cells in tumor microenvironment
- Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?
- The total phenolic fraction of Anemarrhena asphodeloides inhibits inflammation and reduces insulin resistance in adipocytes via regulation of AMP-kinase activity
- Inactivation of NF-ฮบB p65 (RelA) in liver improves insulin sensitivity and inhibits cAMP/PKA pathway
- Interleukin-1 receptor antagonist: a new therapy for type 2 diabetes mellitus
- T2D@ ZJU: a knowledgebase integrating heterogeneous connections associated with type 2 diabetes mellitus
- KSRP ablation enhances brown fat gene program in white adipose tissue through reduced miR-150 expression
- Metformin and salicylate synergistically activate liver AMPK, inhibit lipogenesis and improve insulin sensitivity
- Comparing physical activity programs for managing osteoarthritis in overweight or obese patients
- Role of reninโangiotensinโaldosterone system in adipose tissue dysfunction
- Diosgenin ameliorates palmitate-induced endothelial dysfunction and insulin resistance via blocking IKKฮฒ and IRS-1 pathways
- The Relationship Among Obesity, Inflammation, and Insulin Resistance
- Antidiabetic, antihyperlipidemic and antioxidant effects of the flavonoids
- Interactions between the gut, the brain and brown adipose tissue function
- Anti diabetic effect of CL 316,243 (a ฮฒ3-adrenergic agonist) by down regulation of tumour necrosis factor (TNF-ฮฑ) expression
- Linoleic and ฮฑ-linolenic acid both prevent insulin resistance but have divergent impacts on 1 skeletal muscle mitochondrial bioenergetics in obese Zucker rats 2
- Pathological role of adipose tissue dysfunction in cardio-metabolic disorders
- Nutrigenomic Approaches to Understanding the Transcriptional and Metabolic Responses of Phytochemicals to DietโInduced Obesity and its Complications
- Apoptotic pathways in adipose tissue
- Adipokines and adipose tissue angiogenesis in obesity
- Taking diabetes to heartโderegulation of myocardial lipid metabolism in diabetic cardiomyopathy
- Cis-9, trans-11, trans-13-conjugated linolenic acid induces apoptosis and sustained ERK phosphorylation in 3T3-L1 preadipocytes
- Type 2 diabetes: pathogenesis and natural history
- Roles and tissue source of adiponectin involved in lifestyle modifications
- The platform for adipose tissue expansion during positive energy balance
- Brown adipose tissue harbors a distinct sub-population of regulatory T cells
- Populus balsamifera Extract and Its Active Component Salicortin Reduce Obesity and Attenuate Insulin Resistance in a Diet-Induced Obese Mouse Model
- CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment
- The Potential Epigenetic Modulation of Diabetes Influenced by Nutritional Exposures In Utero
- Regulation of diet-induced adipose tissue and systemic inflammation by salicylates and pioglitazone
- How brown is brown fat that we can see?
- The Poisoning of Our Children: Fighting the Obesity Epidemic in America
- Efficacy of commercial weight-loss programs: an updated systematic review
- Loss of prohibitin induces mitochondrial damages altering ฮฒ-cell function and survival and is responsible for gradual diabetes development
- Do obese children have chronic inflammation & could this contribute to future CVD risk?
- The influence of endotoxemia on the molecular mechanisms of insulin resistance
- INFLUENCES ON TYPE 2 DIABETES AND OBESITY
- Receptor for advanced glycation end products regulates adipocyte hypertrophy and insulin sensitivity in mice: involvement of Toll-like receptor 2
- Myocardin-related transcription factor A regulates conversion of progenitors to beige adipocytes
- Activated Kupffer cells inhibit insulin sensitivity in obese mice
- Heme oxygenase-1 drives metaflammation and insulin resistance in mouse and man
- Two types of brown adipose tissue in humans
- Epigenetic influences on type 2 diabetes and obesity
- Extracellular signal-regulated protein kinase activation in spinal cord contributes to pain hypersensitivity in a mouse model of type 2 diabetes
- Contribution of brown adipose tissue activity to the control of energy balance by GLP-1 receptor signalling in mice
- Targeting inflammation in diabetes: Newer therapeutic options
- Long-term effects of an inpatient weight-loss program in obese children and the role of genetic predisposition-rationale and design of the LOGIC-trial
- Targeting inflammation using salsalate in patients with type 2 diabetes: effects on flow-mediated dilation (TINSAL-FMD)
- Stem cells from adipose tissue and breast cancer: hype, risks and hope
- Mitochondriogenesis and apoptosis: possible cause of vitamin A-mediated adipose loss in WNIN/Ob-obese rats
- Discrimination between brown and white adipose tissue using a 2-point Dixon waterโfat separation method in simultaneous PET/MRI
- Short term fat feeding rapidly increases plasma insulin but does not result in dyslipidaemia
- Genetic deficiency of CD40 in mice exacerbates metabolic manifestations of diet-induced obesity: a dissertation
- Energy metabolism in genetically fat and lean
- The development mechanisms of overweight in young people
- Duration of rise in free fatty acids determines salicylate’s effect on hepatic insulin sensitivity
- Dietary ribonucleic acid suppresses inflammation of adipose tissue and improves glucose intolerance that is mediated by immune cells in C57BL/6 mice fed a high-fatย โฆ
- Adipose tissue-derived serum amyloid A and adipose tissue macrophages in metabolic disease
- Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared with normal birth weight
- Bad Fat or Just More Fat? Murine Models of Metabolically Healthy Obesity
- Dietary supplementation with evodiamine prevents obesity and improves insulin resistance in ageing mice
- Evodiamine inhibits insulin-stimulated mTOR-S6K activation and IRS1 serine phosphorylation in adipocytes and improves glucose tolerance in obeseย โฆ
- Growth hormone (GH) differentially regulates NF-kB activity in preadipocytes and macrophages: implications for GH’s role in adipose tissue homeostasis in obesity
- Burn induces browning of the subcutaneous white adipose tissue in mice and humans
- Role of macrophages in exercise-induced enhancement of insulin sensitivity in skeletal muscle
- Turning off a viral/lipid sensor improves type 2 diabetes
- Selective hepatic insulin resistance, VLDL overproduction, and hypertriglyceridemia
- Effects of high vs. moderate exercise intensity during interval training on lipids and adiponectin levels in obese young females
- Correlated increase of omentin-1 and adiponectin by exenatide, avandamet and dietary change in diet-induced obese rats
- Adipocyte-specific IKKฮฒ signaling suppresses adipose tissue inflammation through an IL-13-dependent paracrine feedback pathway
- Fitness and adiposity are independently associated with cardiometabolic risk in youth
- Advances in an active and passive targeting to tumor and adipose tissues
- Adipose tissue biglycan as a potential anti-inflammatory target of sodium salicylate in mice fed a high fat diet
- Flavanone naringenin: An effective antihyperglycemic and antihyperlipidemic nutraceutical agent on high fat diet fed streptozotocin induced type 2 diabetic rats
- PI3K/AKT pathway in modulating glucose homeostasis and its alteration in diabetes
- Targeting PPARฮฒ/ฮด for the treatment of type 2 diabetes mellitus
- PEDF-induced alteration of metabolism leading to insulin resistance
- Palmitoleic acid prevents palmitic acid-induced macrophage activation and consequent p38 MAPK-mediated skeletal muscle insulin resistance
- Spice up your life: adipose tissue and inflammation
- ER stress in adipocytes and insulin resistance: Mechanisms and significance
- Salicylate acutely stimulates 5โฒ-AMP-activated protein kinase and insulin-independent glucose transport in rat skeletal muscles
- Comparative analysis of plasma metabolomics response to metabolic challenge tests in healthy subjects and influence of the FTO obesity risk allele
- Insulin Resistance-ECAB
- Metabolic Control by Inflammation and Immunity: Myeloid cell TRAF3 promotes metabolic inflammation, insulin resistance, and hepatic steatosis in obesity
- Compliance for Lifestyle Modification among Obese/Overweight School Children from 7-12 Years
- Mice deficient in proglucagon-derived peptides exhibit glucose intolerance on a high-fat diet but are resistant to obesity
- Targeting inflammation in the treatment of type 2 diabetes: time to start
- Central glucocorticoid administration promotes weight gain and increased 11ฮฒ-hydroxysteroid dehydrogenase type 1 expression in white adipose tissue
- Reduced dietary omega-6 to omega-3 fatty acid ratio and 12/15-lipoxygenase deficiency are protective against chronic high fat diet-induced steatohepatitis
- Inflammation and oxidative stress in diabetic nephropathy: new insights on its inhibition as new therapeutic targets
- A peptide derived from G0/G1 switch gene 2 acts as noncompetitive inhibitor of adipose triglyceride lipase
- High-protein diets alters body composition and improves insulin resistance in a rat model of low birth weight
- Novel aspects of metabolic regulation and inflammation in human adipocytes
- Neonatal overnutrition in mice exacerbates high-fat diet-induced metabolic perturbations
- Modulation of the Wnt/ฮฒ-Catenin Pathway in Obesity: A Role for Bile Acid Metabolic Improvement
- Manipulation of the gut microbiota in C57BL/6 mice changes glucose tolerance without affecting weight development and gut mucosal immunity
- Effects of the green tea polyphenol epigallocatechin-3-gallate on high-fat diet-induced insulin resistance and endothelial dysfunction
- The browning of white adipose tissue: some burning issues
- Lifestyle modification decreases arterial stiffness in overweight and obese men: dietary modification vs. exercise training
- Effect of estrogen on expression of prohibitin in white adipose tissue and liver of diet-induced obese rats
- Adipose tissue macrophages in obesity, inflammation, and cancer
- The Genetic Mechanisms Underlying Human Obesity
- Enhanced prereceptor glucocorticoid metabolism and lipogenesis impair insulin signaling in the liver of fructose-fed rats
- 20 Adipose Drug Targets
- IฮบB kinase ฮฒ (IKKฮฒ) does not mediate feedback inhibition of the insulin signalling cascade
- 2, 4-dinitrophenol downregulates genes for diabetes and fatty liver in obese mice
- Effects of DAPT on Serum Vascular Endothelial Growth Factor and Its Soluble Receptor in Obese BALB/C Mice.
- Insulin resistance and atherosclerosis
- Docosahexaenoic acid supplementation improved lipocentric but not glucocentric markers of insulin sensitivity in hypertriglyceridemic men
- AMPK activator-mediated inhibition of endoplasmic reticulum stress ameliorates carrageenan-induced insulin resistance through the suppression of selenoprotein Pย โฆ
- Metabolic characteristics and therapeutic potential of brown and? beige? adipose tissues
- The role of CREB in the liver and adipose tissue
- Molecular aspects of glucose homeostasis in skeletal muscleโA focus on the molecular mechanisms of insulin resistance
- Adipose Tissue-derived progenitor cells and cancer
- Ablation of 3-phosphoinositide-dependent protein kinase 1 (PDK1) in vascular endothelial cells enhances insulin sensitivity by reducing visceral fat and suppressingย โฆ
- Effect of six-month lifestyle intervention on adiponectin, resistin and soluble tumor necrosis factor-ฮฑ receptors in obese adolescents
- Physiology & pathophysiology of human brown adipose tissue
- Selection of aptamers specific for adipose tissue
- Salicylic acid: old and new implications for the treatment of type 2 diabetes?
- n-3 PUFA prevent metabolic disturbances associated with obesity and improve endothelial function in golden Syrian hamsters fed with a high-fat diet
- Bcl10 links saturated fat overnutrition with hepatocellular NF-ฮบB activation and insulin resistance
- The roles of diet and SirT3 levels in mediating signaling network changes in insulin resistance
- Avatars of adipose tissue: the saga of transformation of white fat, the villain into brown fat, the protector. Focus on โInflammation induced by RAW macrophagesย โฆ
- CGI-58/ABHD5-derived signaling lipids regulate systemic inflammation and insulin action
- Oligopeptide complex for targeted non-viral gene delivery to adipocytes
- Dual actions of a novel bifunctional compound to lower glucose in mice with diet-2 induced insulin resistance 3
- Effects of interventions on adiponectin and adiponectin receptors
- Peroxisome proliferator-activated receptor activating hypoglycemic effect of Gardenia jasminoides Ellis aqueous extract and improvement of insulin sensitivityย โฆ
- Nutritional modulation of insulin resistance
- Targeting inflammation through a physical active lifestyle and pharmaceuticals for the treatment of type 2 diabetes
- Erythropoietin inhibits gluconeogenesis and inflammation in the liver and improves glucose intolerance in high-fat diet-fed mice
- Best practice dietetic management of overweight and obese children and adolescents: a 2010 update of a systematic review
- A randomised trial of salsalate for insulin resistance and cardiovascular risk factors in persons with abnormal glucose tolerance
- Cell lysis-free quantum dot multicolor cellular imaging-based mechanism study for TNF-ฮฑ-induced insulin resistance
- Low level of trans-10, cis-12 conjugated linoleic acid decreases adiposity and increases browning independent of inflammatory signaling in overweight Sv129 mice
- Influences of the diabetes surgery on pancreatic B-cells mass
- Type 2 diabetes mellitus: etiology, pathogenesis, and natural history
- Increased Adiposity and Colorectal Cancer
- Novel anti-diabetic effect of SCM-198 via inhibiting the hepatic NF-ฮบB pathway in db/db mice
- An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer’s diseaseโassociated Aฮฒ oligomers
- Linking mitochondrial bioenergetics to insulin resistance via redox biology
- Modified Si-Miao-San inhibits inflammation and promotes glucose disposal in adipocytes through regulation of AMP-kinase
- Browning of Adipose Organ
- Research Article Endocrine and Metabolic Signaling in Retroperitoneal White Adipose Tissue Remodeling during Cold Acclimation
- Pharmacogenomics of cardiovascular complications in diabetes and obesity
- The effect of salsalate on biochemical factors and endothelial dysfunction of prediabetic patients: A randomized clinical trial
- Anti-obesity mechanisms of conjugated linoleic acid (CLA): Role of inflammatory signaling and browning in white adipose tissue
- Antihyperglycemic effect of carvacrol in combination with rosiglitazone in high-fat diet-induced type 2 diabetic C57BL/6J mice
- Regulation of Adipose Tissue Function and Metabolic Homeostasis.
- Nerium oleander distillate improves fat and glucose metabolism in high-fat diet-fed streptozotocin-induced diabetic rats
- Does 8 weeks of strenuous bicycle exercise improve diabetes-related inflammatory cytokines and free fatty acids in type 2 diabetes patients and individuals at highย โฆ
- Effect of diclofenac on plasma glucose level, insulin resistance, inflammatory markers and hepatocytes in diabetic albino rats
- Effectivity Combination of Bitter Melon (Momordica charantia) and Bitter (Andrographis paniculata) Extract to Suppress Proinflammatory Cytokines in Diabetic Mouseย โฆ
- Effect of melatonin on obesity, low-grade inflamation and oxidative stress in diabetic fatty (ZDF) rats
- Thermogenic ability of uncoupling protein 1 in beige adipocytes in mice
- Heterozygous rho kinase2 deficinecy increases whole body insulin sensitivity in mice
- Aspirin-induced inhibition of adipogenesis was p53-dependent and associated with inactivation of pentose phosphate pathway
- Overweight in the military: causes and effects
- Normalization of fasting hyperglycemia is beneficial for successful introduction of small amount of the GLP-1 analog liraglutide in an obese patient with type 2 diabetesย โฆ
- An Approach to Obesity as a Cardiometabolic Disease: Potential Implications for Clinical Practice
- Inflammation induced by RAW macrophages suppresses UCP1 mRNA induction via ERK activation in 10T1/2 adipocytes
- Novel link between inflammation, endothelial dysfunction, and muscle insulin resistance
- Regulation of Fluid-phase Uptake in Podocytes by Albumin-associated Lipids and Role of NKG2D in Obesity-induced Adipose Tissue Inflammation andย โฆ
- Opposite effects of quercetin, luteolin, and epigallocatechin gallate on insulin sensitivity under normal and inflammatory conditions in mice
- The effects of stearidonic acid on 3T3-L1 adipocytes
- Adiponectin is critical in determining susceptibility to depressive behaviors and has antidepressant-like activity
- Toll-like receptor 4 knockout mice are protected against endoplasmic reticulum stress induced by a high-fat diet
- Insulin resistance, metabolic stress, and atherosclerosis
- Understanding the regulation of adipogenesis and adipocyte metabolism in obesity
- The adipose organ: morphological perspectives of adipose tissues
- An intimate relationship between ROS and insulin signalling: implications for antioxidant treatment of fatty liver disease
- PPARฮณ as a therapeutic target in diabetic nephropathy and other renal diseases
- Correlation of Non-alcoholic Fatty Liver Disease and Diabetes Mellitus
- #VALUE!
- Effects of exercise and elevated fatty acid availability on muscle lipid metabolism and insulin sensitivity
- A peptide probe for targeted brown adipose tissue imaging
- Effect of salsalate on insulin action, secretion, and clearance in nondiabetic, insulin-resistant individuals: a randomized, placebo-controlled study
- Insulin Sensitivity in Valproate Treated Epileptics.
- Salsalate improves glycemic control in patients with newly diagnosed type 2 diabetes
- Heme Oxygenase 1 in Hepatocytes Drives Insulin Resistance in Mice and Men
- Effect of natural compounds on insulin signaling
- Activation of NF-ฮบB drives the enhanced survival of adipose tissue macrophages in an obesogenic environment
- Response to comment on โa peptidomimetic targeting white fat causes weight loss and improved insulin resistance in obese monkeysโ
- Effect of medical nutrition therapy on outcomes of patients with pre-diabetes in a rural Nebraska primary care clinic: A pilot study
- Dual actions of a novel bifunctional compound to lower glucose in mice with diet-induced insulin resistance
- Salicylate (salsalate) in patients with type 2 diabetes: a randomized trial
- Expression of โbrown-in-whiteโ adipocyte biomarkers shows gender differences and the influence of early dietary exposure
- Skeletal muscle-specific overproduction of constitutively activated c-Jun N-terminal kinase (JNK) induces insulin resistance in mice
- Identification of novel regulators of mesenchymal stem cell commitment to the brown adipocyte lineage
- Enhanced glucose tolerance and pancreatic beta cell function by low dose aspirin in hyperglycemic insulin-resistant type 2 diabetic Goto-Kakizaki (GK) rats
- The effects of exercise-induced weight loss on ratio of acylated and unacylated ghrelin in obese adolescents
- Technological discipline, obese bodies and gender: A sociological analysis of gastric banding surgery
- Influence of feeding a fish oil-containing diet to young, lean, adult dogs: effects on lipid metabolites, postprandial glycaemia and body weight
- Huang-lian-jie-du-tang protects rats from cardiac damages induced by metabolic disorder by improving inflammation-mediated insulin resistance
- Influencia de la cirugรญa de diabetes sobre la masa de cรฉlulas beta pancreรกticas
- Origin of White and Brown Adipose Cells From Vascular Endothelium: A Dissertation
- Evaluation of the CHANGES weight management programme: Prospective Patients
- Air pollution as a risk factor for type 2 diabetes
- From signal transduction to signal interpretation: an alternative model for the molecular function of insulin receptor substrates
- Effects of a multi-component camp-based intervention on inflammatory markers and adipokines in children: a randomized controlled trial
- An update on the pathogenesis of type 2 diabetes mellitus
- Sodium salicylate treatment in early lactation increases whole-lactation milk and milk fat yield in mature dairy cows
- Using RNA-seq technology to explore the impact of growth hormone on angiogenesis and other cellular pathways in subcutaneous and epididymal adipose tissueย โฆ
- Pathogenesis of type 2 diabetes mellitus
- Adipose tissue dysfunction and inflammation in cardiovascular
- BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy
- An ERP investigation of food cue responsivity in non-obese, weight gain prone individuals
- High density lipoprotein is positively correlated with the changes in circulating total adiponectin and high molecular weight adiponectin during dietary and fenofibrateย โฆ
- THE ROLE OF CGI-58/ABHD5 IN LIPID METABOLISM, INFLAMMATION, AND INSULIN ACTION
- Examining physiological roles of adipose derived VEGF: Consequences in substrate availability and endurance exercise capacity in adipocyte specific VEGFย โฆ
- Vascularization in Engineered Adipose Tissue
- The culture and differentiation of human pluripotent cells into brown and white adipocytes
- Lack of Association of Insulin Receptor Substrate Gene Polymorphisms with Obstructive Sleep Apnea Syndrome
- Inhibition of the IKK pathway restores PI3-K activity in high-fat fed rodent skeletal muscles
- Role of NF-Kappa B (NF-ฮบB) in diabetes
- Isoenergetic feeding of low carbohydrate-high fat diets does not increase brown adipose tissue thermogenic capacity in rats
- Lasting Effects on Body Weight and Mammary Gland Gene Expression in Female Mice upon Early Life Exposure to n-3 but Not n-6 High-Fat Diets
- THE MECHANISMS OF INSULIN ACTION
- Adipose tissue engineering: Obesity disease model and soft tissue regeneration
- Unravelling the link between insulin resistance and androgen excess
- Hepatic expression of constitutively active IKKฮฒ in mice induces low-grade inflammation, but does not cause insulin resistance: a protective role for A20?
- 13 Obesity and Diabetes
- The effect of endurance and resistance training on adiponectin in sedentary young woman
- AMPK activators as a drug for diabetes, cancer and cardiovascular disease
- On the horizon: new oral therapies for type 2 diabetes mellitus
- Oestrogen signalling in white adipose progenitor cells inhibits differentiation into brown adipose and smooth muscle cells
- Mechanisms Mediating Antidiabetic Effects of Serviceberry extracts, Curcumin, and Stilbenes
- #VALUE!
- Loss of adipocyte VEGF impairs endurance exercise capacity in mice
- A critical appraisal of brown adipose tissue metabolism in humans
- Gene expression of sternohyoid and diaphragm muscles in type 2 diabetic rats
- #VALUE!
- High fat diet increases tumor incidence in the intestine due to alterations in microbial communities and immune system
- Insulin-and growth factor-resistance impairs vascular regeneration in diabetes mellitus
- On the horizon: New oral therapies for type 2 diabetes mellitus
- Bone mineral density is associated with total body weight loss ten years after Roux-en-Y gastric bypass
- Do anti-angiogenic cancer therapies increase risk of significant weight loss?
- Pathogenesis of diabetes-tuberculosis comorbidity, The
- Suppression of adipogenesis by pathogenic seipin mutant is associated with inflammatory response
- ร-cell reserve in insulin resistant pregnant mice
- Research Article Nerium oleander Distillate Improves Fat and Glucose Metabolism in High-Fat Diet-Fed Streptozotocin-Induced Diabetic Rats
- Omega 3 fatty acids promote macrophage reverse cholesterol transport in hamster fed high fat diet
- Periodontitis modulates insulin signaling, c-Jun N-terminal kinase activity, IKK activity, and insulin receptor substrate-1 ser 307 phosphorylation in muscle andย โฆ
- Cellular plasticity in white adipose tissue: in vivo identification of bipotent adipocyte progenitors in adult white adipose tissue
- Effects of Exercise and Diet-Induced Weight Loss in Overweight/Obese Women on Characterization of Serum/White Blood Cells, microRNAs and Cytokine Geneย โฆ
- #VALUE!
- Insulin plant (Costus pictus) extract improves insulin sensitivity and ameliorates atherogenic dyslipidaemia in fructose induced insulin resistant rats: Molecularย โฆ
- CHANGES Weight Management Service Evaluation
- Studies Defining The Local Function of Adipose Tissue IGF1 And The Role of Lipolysis in Adipose Tissue Macrophage Lipid Uptake
- Modified Si-Miao-San () regulates adipokine expression and ameliorates insulin resistance by targeting IKKฮฒ/Insulin receptor substrate-1 in mice.
- The interrelationship between insulin resistane and Alzheimer development
- Factors of Inflammation in Haitian Americans and African Americans with and without Type 2 Diabetes
- Genome-wide profiling of peroxisome proliferator-activated receptor ฮณ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective bindingย โฆ
- Diabetes prevention education aimed at Dutch and Turkish relatives at risk: Development and evaluation of DiAlert
- Identification of the NF-ฮบB inhibitor A20 as a key regulator for human adipogenesis
- Regulation of hepatic insulin receptor activity following injury
- A meta-analysis of salicylates for type 2 diabetes mellitus
- Resveratrol and Metformin Combination Therapy in Prevention and Treatment of Insulin Resistance
- Impact of Co-Administration of Salicylic Acid with Glibenclamide in a Rat Model of Type 2 Diabetes Mellitus
- Effects of Amino Acids on the Regulation of Insulin Sensitivity in Skeletal Muscle Cells
- Crosstalk between insulin and Toll-like receptor signaling pathways in the central nervous system
- Peptides as targeting probes against tumor vasculature for diagnosis and drug delivery
- The Effects of Salsalate on Biochemical Factors of Serum and Endothelial Dysfunction in Patients with Newly Diagnosed Type 2 Diabetes
- Novel players in rescue of ฮฒ-cells from inflammation-mediated destruction in Type 2 Diabetes Mellitus
- Non-steroidal anti-inflammatory drugs activate NADPH oxidase in adipocytes and raise the H2O2 pool to prevent cAMP-stimulated protein kinase aย โฆ
- #VALUE!
- Alteration in lymphocyte population and humoral immune response in type 2 diabetic GotoโKakizaki rats
- Rosiglitazone inhibits hepatic insulin resistance induced by chronic pancreatitis and IKK-ฮฒ/NF-ฮบB expression in liver
- prevents vascular endothelial dysfunction in a type 2 diabetic rat model
- High dose of aspirin moderates diabetes-induced changes of heart glycogen/glucose metabolism in rats
- Insulin transcytosis across adipose microvascular endothelial cells: Mechanism and physiological implications
- Reversal of obesity-driven aggressiveness of endometrial cancer by metformin
- Reversal of obesity and liver steatosis in mice via inhibition of aryl hydrocarbon receptor and altered gene expression of CYP1B1, PPARฮฑ, SCD1, and osteopontin
- Adipose tissue supports normalization of macrophage and liver lipid handling in obesity reversal
- Obesity-related perivascular adipose tissue damage is reversed by sustained weight loss in the rat
- Reversal of high fat diet-induced obesity improves glucose tolerance, inflammatory response, ฮฒ-amyloid accumulation and cognitive decline in the APP/PSEN1 mouseย โฆ
- Reversal of obesity: The quest for the optimum dietary regimen
- Nanotechnology advances towards development of targeted-treatment for obesity
- Inhibiting glycogen synthase kinase 3 reverses obesity-induced white adipose tissue inflammation by regulating apoptosis inhibitor of macrophage/CD5L-mediatedย โฆ
- Short chain fatty acids in the colon and peripheral tissues: a focus on butyrate, colon cancer, obesity and insulin resistance
- Reversal of obesity-driven aggressiveness of endometrial cancer by metformin
- Resveratrol reverses the adverse effects of a diet-induced obese murine model on oocyte quality and zona pellucida softening
- Obesity-linked PPARฮณ S273 phosphorylation promotes insulin resistance through growth differentiation factor 3
- Obesity-related epigenetic changes after bariatric surgery
- Blood-brain barriers in obesity
- To be or not to be obese: Impact of obesity on lymphatic function
- Anti-obesity and insulin-sensitising effects of a glycosaminoglycan mix
- SUN-543 Real World Evidence of Successful Weight Management for the Obese Population: Complete Reversal of Obesity Related Metabolic Co-Morbiditiesย โฆ
- Simvastatin has anti-tumorigenic effects in endometrial cancer via reversal of obesity-driven upregulation of lipid biosynthesis
- Attenuation of Obesity, Hepatic Steatosis and Reversal of Atherosclerosis by the Flavonoids Naringenin and Nobiletin
- Mild suppression of hyperinsulinemia to treat obesity and insulin resistance
- Vascular targeted nanotherapeutic approach for obesity treatment
- Dietary options for rodents in the study of obesity
- Role of innate and adaptive immunity in obesity-associated metabolic disease
- Dynamic energy balance and obesity prevention
- Caloric restriction recovers impaired ฮฒ-cell-ฮฒ-cell gap junction coupling, calcium oscillation coordination, and insulin secretion in prediabetic mice
- Genetics of obesity: can an old dog teach us new tricks?
- Milestone weight loss goals (weight normalization and remission of obesity) after gastric bypass surgery: long-term results from the University of Michigan
- Obesity and breast cancerโwhat’s new?
- #VALUE!
- Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesityโinduced chronic kidney disease
- Hypothalamic Pomcโdeficiency Impairs the Function of Leptin to Decrease Food Intake and Bodyweight
- How does exercise support dietary approaches to weight loss and better health?
- Comment on: Five-year changes in dietary intake and body composition in adolescents with severe obesity undergoing laparoscopic Roux-en-Y gastric bypassย โฆ
- Long-term remission of type 2 diabetesโtwo roads to the elusive goal
- Naltrexone/bupropion for the treatment of obesity and obesity with Type 2 diabetes
- Dietary management of obesity: a review of the evidence
- Studies of perivascular adipose tissue function in obesity and following diet-induced weight loss
- The obesity epidemic in the face of homeostatic body weight regulation: What went wrong and how can it be fixed?
- Evidence-Based Guidelines for the Treatment of Obesity
- Animal models of obesity and diabetes mellitus
- Appetite control with relevance to mitochondrial biogenesis and activation of post-prandial lipid metabolism in obesity linked diabetes
- Effect of obesity on bladder cancer and renal cell carcinoma incidence and survival
- The effects of bariatric surgery on gut microbiota in patients with obesity: a review of the literature
- Whole-Food Plant-Based Lifestyle Program and Decreased Obesity: A 10-Year Follow-up
- Comprehensive molecular characterization of surgical vs. dietary weight loss: impact on mammary tumor burden
- Promises of nanotherapeutics in obesity
- Bilobalide abates inflammation, insulin resistance and secretion of angiogenic factors induced by hypoxia in 3T3-L1 adipocytes by controlling NF-ฮบB and JNKย โฆ
- The possible factors affecting microglial activation in cases of obesity with cognitive dysfunction
- Vascular risk reduction in obesity through reduced granulocyte burden and improved angiogenic monocyte content following bariatric surgery
- Preclinical efficacy of the GPER-selective agonist G-1 in mouse models of obesity and diabetes
- Akkermansia muciniphila-Derived Extracellular Vesicles as a Mucosal Delivery Vector for Amelioration of Obesity in Mice
- Caloric Restriction recovers impaired ฮฒ-cell-ฮฒ-cell coupling, calcium oscillation coordination and insulin secretion in prediabetic mice
- Targeting IฮบB kinase ฮฒ in adipocyte lineage cells for treatment of obesity and metabolic dysfunctions
- Profound and redundant functions of arcuate neurons in obesity development
- Angiogenesis in obesity
- Understanding human physiological limitations and societal pressures in favor of overeating helps to avoid obesity
- Obesity in older people: A new scenario and a new challenger
- Potential role of aryl hydrocarbon receptor signaling in childhood obesity
- Childhood obesity plans already show progress, minister claims
- Long-term exercise-secreted extracellular vesicles promote browning of white adipocytes by suppressing miR-191a-5p
- Gastric bypass surgery in lean adolescent mice prevents diet-induced obesity later in life
- Dietary nitrite reverses features of postmenopausal metabolic syndrome induced by high-fat diet and ovariectomy in mice
- Dibenzazepine-loaded nanoparticles induce local browning of white adipose tissue to counteract obesity
- Sleeve gastrectomy reversed obesity-induced hypogonadism in a rat model by regulating inflammatory responses in the hypothalamus and testis
- Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors
- TNP [N2-(m-Trifluorobenzyl), N6-(p-nitrobenzyl) purine] ameliorates diet induced obesity and insulin resistance via inhibition of the IP6K1 pathway
- Attenuation of obesity and insulin resistance by fish oil supplementation is associated with improved skeletal muscle mitochondrial function in mice fed a high-fat diet
- Differential effects of diet and weight on taste responses in dietโinduced obese mice
- Potential relationship between dietary long-chain saturated fatty acids and hypothalamic dysfunction in obesity
- Preventing diet-induced obesity in mice by adipose tissue transformation and angiogenesis using targeted nanoparticles
- Perioperative course, weight loss and resolution of comorbidities after primary sleeve gastrectomy for morbid obesity: are there differences between adolescents andย โฆ
- ProhibitinโAt the crossroads of obesity-linked diabetes and cancer
- THE PERCEPTION OF PHYSIOTHERAPISTS OF KARACHI IN THEIR ROLE TO REHABILITATE AND MANAGE OBESITY
- Resolution of refractory iron deficiency anemia following sleeve gastrectomy in an adolescent with severe obesity
- Persistent microbiome alterations modulate the rate of post-dieting weight regain
- Legend of weight loss: a crosstalk between the bariatric surgery and the brain
- Zfp423 maintains white adipocyte identity through suppression of the beige cell thermogenic gene program
- Trained immunity: linking obesity and cardiovascular disease across the life-course?
- Long-term atorvastatin or the combination of atorvastatin and nicotinamide ameliorate insulin resistance and left ventricular diastolic dysfunction in a murine model ofย โฆ
- Exploring the impact of obesity on skeletal muscle function in older age
- An eclectic cast of cellular actors orchestrates innate immune responses in the mechanisms driving obesity and metabolic perturbation
- ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
- Obesity and metabolic health status are determinants for the clinical expression of hypertrophic cardiomyopathy
- Beiging of white adipose tissue as a therapeutic strategy for weight loss in humans
- Targeted delivery of CRISPR interference system against Fabp4 to white adipocytes ameliorates obesity, inflammation, hepatic steatosis, and insulin resistance
- Obesity, body weight regulation and the brain: insights from fMRI
- #VALUE!
- Gut microbiota modulation and its relationship with obesity using prebiotic fibers and probiotics: a review
- The correlation between cardiorespiratory fatigue and lower extremity joint moments in obese individuals and the associated reverse causation
- Sex-associated preventive effects of low-dose aspirin on obesity and non-alcoholic fatty liver disease in mouse offspring with over-nutrition in utero
- Downward trends in the prevalence of childhood overweight in two pilot towns taking part in the VIASANO communityโbased programme in B elgium: data from aย โฆ
- DNA methylation changes more slowly than physiological states in response to weight loss in genetically diverse mouse strains
- #VALUE!
- The Effects of Diet Induced Obesity and Metabolic Irregularities on Hippocampal-Based Cognition and Neuroplasticity in Young Female and Male Rat
- Turning the tables on obesity: young people, IT and social movements
- Interleukin-37 treatment of mice with metabolic syndrome improves insulin sensitivity and reduces pro-inflammatory cytokine production in adipose tissue
- Skeletal muscle inflammation and insulin resistance in obesity
- New therapeutic approaches for the treatment of obesity
- Transcriptional dysregulation of adipose tissue autophagy in obesity
- Deletion of the glutaredoxin-2 gene protects mice from diet-induced weight gain, which correlates with increased mitochondrial respiration and proton leaks in skeletalย โฆ
- Exercise, adipokines and pediatric obesity: a meta-analysis of randomized controlled trials
- Pharmacotherapy of obesity: limits and perspectives
- The role of WIC in obesity prevention
- Neutrophil elastase regulates emergency myelopoiesis preceding systemic inflammation in diet-induced obesity
- Obesity in adolescents and youth: the case for and against bariatric surgery
- Association between exercise and treatment with liraglutide in obese rats by cafeteria diet
- Adipose tissue heterogeneity-development and application of nonlinear microscopy methods
- Obesity prevention in a city state: lessons from New York City during the Bloomberg Administration
- Link between chemerin, central obesity, and parameters of the Metabolic Syndrome: findings from a longitudinal study in obese children participating in a lifestyleย โฆ
- Obesity and associated comorbidities in people and companion animals: a one health perspective
- An Extract of Russian Tarragon Prevents ObesityโRelated Ectopic Lipid Accumulation
- Transgenerational epigenetics, paternal obesity, and insulin resistance
- Post-dieting weight gain: the role of persistent microbiome changes
- Vascular endothelial regulation of obesity-associated insulin resistance
- Selective activation of Gs signaling in adipocytes causes striking metabolic improvements in mice
- #VALUE!
- Prohibitin: A new player in immunometabolism and in linking obesity and inflammation with cancer
- How do structurally distinct compounds exert functionally identical effects in combating obesity?
- Peptide-functionalized quantum dots for potential applications in the imaging and treatment of obesity
- Targeted proapoptotic peptides depleting adipose stromal cells inhibit tumor growth
- A systematic review of studies of DNA methylation in the context of a weight loss intervention
- Targeting ceramide metabolism in obesity
- Chronic adipose tissue inflammation linking obesity to insulin resistance and type 2 diabetes
- Food for thought: reward mechanisms and hedonic overeating in obesity
- Adipocyte cannabinoid receptor CB1 regulates energy homeostasis and alternatively activated macrophages
- The gut microbiome, obesity, and weight control in women’s reproductive health
- Carotenoids and carotenoid conversion products in adipose tissue biology and obesity: Pre-clinical and human studies
- A transcriptomic analysis reveals novel patterns of gene expression during 3T3-L1 adipocyte differentiation
- Effect of resveratrol on adipokines and myokines involved in fat browning: Perspectives in healthy weight against obesity
- Visceral adipose tissue macrophage-targeted TACE silencing to treat obesity-induced type 2 diabetes
- #VALUE!
- Food cues and obesity: overpowering hormones and energy balance regulation
- The role of the Nrf2 signaling in obesity and insulin resistance
- Activation of neuregulin-4 in adipocytes improves metabolic health by enhancing adipose tissue angiogenesis
- Mouse modeling of obese lung disease. Insights and caveats
- Steroid metabolomic signature of insulin resistance in childhood obesity
- PDGFRฮฒ regulates adipose tissue expansion and glucose metabolism via vascular remodeling in diet-induced obesity
- Microbial medicine: prebiotic and probiotic functional foods to target obesity and metabolic syndrome
- P62 plasmid can alleviate diet-induced obesity and metabolic dysfunctions
- Brown adipose tissue imaging using the TSPO tracer [18F] fluoromethyl-PBR28-d2: A comparison with [18F] FDG
- Deletion of interleukin 1 receptor-associated kinase 1 (Irak1) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle
- Thyme oxymel by improving of inflammation, oxidative stress, dyslipidemia and homeostasis of some trace elements ameliorates obesity induced by highย โฆ
- Obesity and cardiovascular disease: a risk factor or a risk marker?
- Wnt signaling mediates TLR pathway and promote unrestrained adipogenesis and metaflammation: therapeutic targets for obesity and type 2 diabetes
- Adipocyte dysfunction, inflammation, and insulin resistance in obesity
- Association of oxytocin with glucose intolerance and inflammation biomarkers in metabolic syndrome patients with and without prediabetes
- Vascular risk in obesity: Facts, misconceptions and the unknown
- Investigating the Role of LRG1 in Obesity and Adipose Tissue Remodelling
- Altered adipose tissue and adipocyte function in the pathogenesis of metabolic syndrome
- Adipose natural killer cells regulate adipose tissue macrophages to promote insulin resistance in obesity
- Mast cell stabilizers obviate high fat diet-induced renal dysfunction in rats
- 10 Mechanisms Mediating Obesity-Induced Inflammation and Insulin Resistance
- Gut microbiota as a trigger for metabolic inflammation in obesity and type 2 diabetes
- High fat diet and associated changes in the expression of microโRNAs in tissue: Lessons learned from animal studies
- Fatty acids and chronic low grade inflammation associated with obesity and the metabolic syndrome
- Central serotonin transporter availability in highly obese individuals compared with non-obese controls: A [11C] DASB positron emission tomography study
- Adiposity as a full mediator of the influence of cardiorespiratory fitness and inflammation in schoolchildren: The FUPRECOL Study
- Weight management and physical activity throughout the cancer care continuum
- Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness
- Obesity and the acute respiratory distress syndrome
- Saturated fatty acids, obesity, and the nucleotide oligomerization domainโlike receptor protein 3 (NLRP3) inflammasome in asthmatic patients
- Hypoglycemic activity of 6-bromoembelin and vilangin in high-fat diet fed-streptozotocin-induced type 2 diabetic rats and molecular docking studies
- Inflammatory signaling and brown fat activity
- Targeting innate immune mediators in type 1 and type 2 diabetes
- Brassinin, a phytoalexin in cruciferous vegetables, suppresses obesityโinduced inflammatory responses through the Nrf2โHOโ1 signaling pathway in an adipocyteย โฆ
- Treatment of insulin resistance in obesity-associated type 2 diabetes mellitus through adiponectin gene therapy
- Training motor responses to food: A novel treatment for obesity targeting implicit processes
- Obesity 13 of Diabetes
- Levels of metabolic markers in drug-naive prediabetic and type 2 diabetic patients
- Obesity as a Disease
- Diabetes Mellitus and Glucose Metabolism
- Anti-inflammatory actions of (โ)-epicatechin in the adipose tissue of obese mice
- A phytoestrogen secoisolariciresinol diglucoside induces browning of white adipose tissue and activates non-shivering thermogenesis through AMPK pathway
- Effects of mixed carotenoids on adipokines and abdominal adiposity in children: a pilot study
- Cellular aging contributes to failure of cold-induced beige adipocyte formation in old mice and humans
- 2-OHOA supplementation reduced adiposity and improved cardiometabolic risk to a greater extent than n-3 PUFA in obese mice
- Obesity causes irreversible mitochondria failure in visceral adipose tissue despite successful anti-obesogenic lifestyle-based interventions
- Effect of 8 weeks sprint interval training on serum levels of Adiponectin and insulin in overweight children
- Role of mitochondria in the skeletal muscle metabolism in obesity and type 2 diabetes
- Insulin-sparing and fungible effects of E4orf1 combined with an adipocyte-targeting sequence in mouse models of type 1 and type 2 diabetes
- Curcumin prevents inflammatory response, oxidative stress and insulin resistance in high fructose fed male Wistar rats: Potential role of serine kinases
- IKKฮฒ is essential for adipocyte survival and adaptive adipose remodeling in obesity
- Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice
- MS-275, a class 1 histone deacetylase inhibitor augments glucagon-like peptide-1 receptor agonism to improve glycemic control and reduce obesity in diet-inducedย โฆ
- Neuroinflammation and white matter alterations in obesity assessed by diffusion basis spectrum imaging
- Exercise-induced adaptations to white and brown adipose tissue
- The colors of adipose tissue
- Lysimachia Capillipes inhibit adipogenesis via angiogenesis inhibition
- Neural vulnerability factors that increase risk for future weight gain.
- Obesity, estrogens and adipose tissue dysfunctionโimplications for pulmonary arterial hypertension
- Intermittent fasting and ‘metabolic switch’: Effects on metabolic syndrome, prediabetes and type 2 diabetes
- Mean Platelet Volume (MPV) as an inflammatory marker in type 2 diabetes mellitus and obesity
- Regulatory roles of invariant natural killer T cells in adipose tissue inflammation: defenders against obesity-induced metabolic complications
- Glucose-6-phosphate dehydrogenase deficiency improves insulin resistance with reduced adipose tissue inflammation in obesity
- Hypothalamic insulin-sensitizing effect of exenatide in dietary induced rat model of obesity
- Metabolic Abnormalities and Adipose Tissue Leukocyte Dynamics in a Murine Model of Obesity, Weight Loss, and Weight Regain
- Luteolin reduces adipose tissue macrophage inflammation and insulin resistance in postmenopausal obese mice
- Adipose tissue inflammation in insulin resistance: review of mechanisms mediating anti-inflammatory effects of omega-3 polyunsaturated fatty acids
- Peptides and peptidomimetics as potential antiobesity agents: overview of current status
- Sex differences in sympathetic innervation and browning of white adipose tissue of mice
- Brown adipose tissue: The heat is on the heart
- The stability of children’s weight status over time, and the role of television, physical activity, and diet
- Elevated Serum Levels of Adropin in Patients with Type 2 Diabetes Mellitus and its Association with Insulin Resistance Insulin Resistance
- Adipokines: potential therapeutic targets for vascular dysfunction in type II diabetes mellitus and obesity
- Repeatability of brown adipose tissue measurements on FDG PET/CT following a simple cooling procedure for BAT activation
- Association of high-fat diet with neuroinflammation, anxiety-like defensive behavioral responses, and altered thermoregulatory responses in male rats
- Mechanisms of Obesity Induced Impairment of Reproduction
- Physical Exercise and White Adipose Tissue Plasticity in the Context of Obesity
- Effect of shortโterm probiotic Enterococcus faecium SF68 dietary supplementation in overweight and obese cats without comorbidities
- Effects of microalgal polyunsaturated fatty acid oil on body weight and lipid accumulation in the liver of C57BL/6 mice fed a high fat diet
- Corn oil versus lard: Metabolic effects of omega-3 fatty acids in mice fed obesogenic diets with different fatty acid composition
- Obesity, NASH, and HCC
- Nanomedicine for obesity treatment
- Obesity accelerates age defects in mouse and human B cells
- Structured Physical Activity and Dietary Education Program for Obese Adolescents: An Evaluation of a Quality Improvement Project at a Rural Primary Care Clinic
- Alteration of adipose tissue immune cell milieu towards the suppression of inflammation in high fat diet fed mice by flaxseed oil supplementation
- Differential modulation of white adipose tissue endocannabinoid levels by n-3 fatty acids in obese mice and type 2 diabetic patients
- Dietary supplementation with purified citrus limonin glucoside does not alter ex vivo functions of circulating T lymphocytes or monocytes in overweight/obese humanย โฆ
- Current mechanisms in obesity and tumor progression
- The role of ceramides in insulin resistance
- Endothelial cells: new players in obesity and related metabolic disorders
- Fructose-enriched diet induces inflammation and reduces antioxidative defense in visceral adipose tissue of young female rats
- Exendin-4 modifies adipogenesis of human adipose-derived stromal cells isolated from omentum through multiple mechanisms
- Clinical Manifestations of Insulin Resistance in Youth
- Therapeutic approaches targeting inflammation for diabetes and associated cardiovascular risk
- The Aryl Hydrocarbon Receptor and Diet-Induced Obesity: An Investigation of How the Canonical Toxicant Receptor Modulates the Obese State via Activation andย โฆ
- Catabolic and anabolic faces of insulin resistance and their disorders: a new insight into circadian control of metabolic disorders leading to diabetes
- Feeding obese diabetic mice a genistein diet induces thermogenic and metabolic change
- Plasma acylcarnitines and amino acid levels as an early complex biomarker of propensity to high-fat diet-induced obesity in mice
- Aegeline inspired synthesis of novel ฮฒ3-AR agonist improves insulin sensitivity in vitro and in vivo models of insulin resistance
- Functional and molecular adaptations of enteroendocrine L-cells in male obese mice are associated with preservation of pancreatic ฮฑ-cell function and prevention ofย โฆ
- Roles of daily diet and beta-adrenergic system in the treatment of obesity and diabetes
- Type II diabetes mellitus and obesity: Common links, existing therapeutics and future developments
- Multiple benefits of targeting inflammation in the treatment of type 2 diabetes
- Meta-inflammation and cardiometabolic disease in obesity: Can heat therapy help?
- Stromal cell-derived factor 1 (SDF1) attenuates platelet-derived growth factor-B (PDGF-B)-induced vascular remodeling for adipose tissue expansion in obesity
- Targeted hyaluronateโhollow gold nanosphere conjugate for anti-obesity photothermal lipolysis
- Anti-toll-like receptor 2 antibody ameliorates hepatic injury, inflammation, fibrosis and steatosis in obesity-related metabolic disorder rats via regulating MAPK and NFย โฆ
- Stem cell and obesity: current state and future perspective
- Peroxisome proliferator-activated receptor ฮณ in white and brown adipocyte regulation and differentiation
- Evaluation of Urolithin, a Pomegranate Metabolite as an Inhibitor of Obesity Driven Endoplasmic Reticulum Stress and Inflammation
- The protective effects of Chinese yam polysaccharide against obesity-induced insulin resistance
- Urtica dioica Whole Vegetable as a Functional Food Targeting Fat Accumulation and Insulin Resistance-a Preliminary Study in a Mouse Pre-Diabetic Model
- Effects of growth hormone on uncoupling protein 1 in white adipose tissues in obese mice
- Clinical application potential of small molecules that induce brown adipose tissue thermogenesis by improving fat metabolism
- Effect of an 8-week individualized training program on blood biomarkers, adipokines and endothelial function in obese young adolescents with and without metabolicย โฆ
- ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
- Insulin resistance in HIV-patients: causes and consequences
- Non-glycanated decorin is a drug target on human adipose stromal cells
- The effect of saffron on weight and lipid profile: A systematic review, metaโanalysis, and doseโresponse of randomized clinical trials
- Browning of white adipose tissue induced by the ร3 agonist CL-316,243 after local and systemic treatment-PK-PD relationship
- Bitter Orange (Citrus aurantium Linnรฉ) Improves Obesity by Regulating Adipogenesis and Thermogenesis through AMPK Activation
- The aryl hydrocarbon receptor in energy balance: the road from dioxin-induced wasting syndrome to combating obesity with ahr ligands
- CREG1 heterozygous mice are susceptible to high fat diet-induced obesity and insulin resistance
- Flaxseed oil alleviates chronic HFD-induced insulin resistance through remodeling lipid homeostasis in obese adipose tissue
- Premature ejaculation in type II diabetes mellitus patients: association with glycemic control
- Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway
- ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity
- Beneficial Health Effect of Aquarobics (Role of Adiponectin on Women with Obesity)
- Essential roles for the non-canonical IฮบB kinases in linking inflammation to cancer, obesity, and diabetes
- Intake of a Western diet containing cod instead of pork alters fatty acid composition in tissue phospholipids and attenuates obesity and hepatic lipid accumulation inย โฆ
- Dietary Supplementation with Dunaliella Tertiolecta Prevents Whitening of Brown Fat and Controls Diet-Induced Obesity at Thermoneutrality in Mice
- Muscle insulin resistance and the inflamed microvasculature: fire from within
- Obesity and inflammation: Role of adipokines
- Adipose tissue remodeling: its role in energy metabolism and metabolic disorders
- MKK6 controls T3-mediated browning of white adipose tissue
- A Retrospective Comparative Analysis on the Effectiveness of Pharmacologic Weight Loss
- Macrophage infiltration into obese adipose tissues suppresses the induction of UCP1 level in mice
- Latent inflammation and insulin resistance in adipose tissue
- Influences of nutritional food label understanding in African-American Women with obesity
- Classifying the linkage between adipose tissue inflammation and tumor growth through cancer-associated adipocytes
- Effects of recombinant irisin on body mass index, serum insulin, luteinizing hormone and testosterone levels in obese female BALB/c mice
- Fibroblast Growth Factor 21 Expression in Mice with Altered Growth Hormone Action: Links to Obesity, Type 2 Diabetes Mellitus, and Increased Longevity
- Comprehensive functional screening of miRNAs involved in fat cell insulin sensitivity among women
- (-)-Epicatechin and its metabolites prevent palmitate-induced NADPH oxidase upregulation, oxidative stress and insulin resistance in HepG2 cells
- Metabolic and molecular mechanisms of macrophage polarisation and adipose tissue insulin resistance
- Interplay between H6PDH and 11ฮฒ-HSD1 implicated in the pathogenesis of type 2 diabetes mellitus
- Curcumin inhibits lipolysis via suppression of ER stress in adipose tissue and prevents hepatic insulin resistance [S]
- Humans and mice display opposing patterns of โbrowningโ gene expression in visceral and subcutaneous white adipose tissue depots
- Influences of Nutritional Food Label Understanding on African American Women with Obesity
- PI3Ka-Akt1-mediated Prdm4 induction in adipose tissue increases energy expenditure, inhibits weight gain, and improves insulin resistance in diet-inducedย โฆ
- Using neuroimaging to investigate the impact of Mandoleanยฎ training in young people with obesity: a pilot randomised controlled trial
- Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity
- Hypoglycaemic effect and mechanism of an RG-II type polysaccharide purified from Aconitum coreanum in diet-induced obese mice
- Weight gain is associated with changes in neural response to palatable food tastes varying in sugar and fat and palatable food images: a repeated-measures fMRIย โฆ
- Managing the Obese Living Kidney Donor
- Drugs involved in dyslipidemia and obesity treatment: focus on adipose tissue
- Exercise regulation of adipose tissue
- Combined effect of metformin with ascorbic acid versus acetyl salicylic acid on diabetes-related cardiovascular complication; a 12-month single blindย โฆ
- Corosolic acid inhibits adipose tissue inflammation and ameliorates insulin resistance via AMPK activation in high-fat fed mice
- Obesity and Exercice: Effects of different Chronic Exercise Models on visceralapipose tissue from obese animals.
- Prohibitin in adipose and immune functions
- Adipose tissue distribution, inflammation and its metabolic consequences, including diabetes and cardiovascular disease
- Does physical activity-based intervention improve systemic proinflammatory cytokine levels in overweight or obese children and adolescents? Insights from a metaย โฆ
- Nutritional properties of protein sources on diet-induced obesity, hepatic lipid accumulation, and fatty acid composition in mice
- Innate obesity, revealed by selection markers, confers significant imprint of hypothalamic genes controlling energy expenditure
- Type 2 diabetes and its impact on the immune system
- Molecular mechanisms of insulin resistance: An update
- Prohibitin/annexin 2 interaction regulates fatty acid transport in adipose tissue
- Chenodeoxycholic acid attenuates highโfat dietโinduced obesity and hyperglycemia via the G proteinโcoupled bile acid receptor 1 and proliferatorโactivatedย โฆ
- Heat therapy improves glucose tolerance and adipose tissue insulin signaling in polycystic ovary syndrome
- EPA and DHA elicit distinct transcriptional responses to high-fat feeding in skeletal muscle and liver
- Pentamethylquercetin induces adipose browning and exerts beneficial effects in 3T3-L1 adipocytes and high-fat diet-fed mice
- Adipose tissue: a safe haven for parasites?
- GNB3 overexpression causes obesity and metabolic syndrome
- PAQR3 regulates phosphorylation of FoxO1 in insulin-resistant HepG2 cells via NF-ฮบB signaling pathway
- Antisense oligonucleotide and thyroid hormone conjugates for obesity treatment
- Searching for evidence of an anti-inflammatory diet in children: a systematic review of randomized controlled trials for pediatric obesity interventions with a focus onย โฆ
- Weight suppression increases odds for future onset of anorexia nervosa, bulimia nervosa, and purging disorder, but not binge eating disorder
- Aspirin mitigated tumor growth in obese mice involving metabolic inhibition
- Obese adipose tissue secretion induces inflammation in preadipocytes: Role of Toll-like receptor-4
- NAFLD and diabetes mellitus
- Efficacy of weight loss intervention can be predicted based on early alterations of fMRI food cue reactivity in the striatum
- Mitochondrial Damage Accumulation in Oocytes-A Potential Link Between Maternal Obesity and Increased Cardiometabolic Disease Risk in Offspring
- Salsalate activates skeletal muscle thermogenesis and protects mice from high-fat diet induced metabolic dysfunction
- Control of brown and beige fat development
- A possible Role of Salicylates in Diabetes Type II
- Metabolic health, insulin, and breast cancer: why oncologists should care about insulin
- Nonalcoholic fatty liver disease induced by high-fat diet in C57bl/6 models
- Different and unequal: a qualitative evaluation of salient factors influencing energy intake in adults with overweight and obesity
- Mechanisms of inflammatory responses and development of insulin resistance: how are they interlinked?
- Layperson-led vs professional-led behavioral interventions for weight loss in pediatric obesity: a systematic review and meta-analysis
- Renal insulin sensitizing effect of exenatide in a high-fat diet obesity rat model
- Inflammation in human adipose tissuesโShades of gray, rather than white and brown
- Differential expression network analysis for diabetes mellitus type 2 based on expressed level of islet cells
- Hypocaloric versus Ad Libitum Diet on Cardiometabolic Markers and Microbiota of Overweight Individuals Performing Intense Exercise
- Viral and nonviral transfer of genetic materials to adipose tissues: Toward a gold standard approach
- Adipose stromal cell expansion and exhaustion: mechanisms and consequences
- Hypertension in diabetes and the risk of cardiovascular disease
- The mechanism by which safflower yellow decreases body fat mass and improves insulin sensitivity in HFD-induced obese mice
- Postnatal leptin surge is critical for the transient induction of the developmental beige adipocytes in mice
- The effects of metformin on high-fat diet-induced neuroinflammation and cognitive impairment
- Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells
- Unsaturated fatty acids from flaxseed oil and exercise modulate GPR120 but not GPR40 in the liver of obese mice: a new anti-inflammatory approach
- Preliminary report of inflammatory markers, oxidative stress, and insulin resistance in adolescents of different ethnicities
- Adipocyte-secreted chemerin is processed to a variety of isoforms and influences MMP3 and chemokine secretion through an NFkB-dependent mechanism
- TonEBP in macrophages and adipocytes contributes to obesity and type 2 diabetes
- Ageing, colonic health, obesity and the gut microbiota
- TNF-ฮฑ as an adipokine
- Parental Self-Efficacy, Feeding Practices and Styles, and Obesity in Mexican American Children
- Environmental obesogens and their impact on susceptibility to obesity: new mechanisms
- Chronic ephedrine administration decreases brown adipose tissue activity in a randomised controlled human trial: implications for obesity
- #VALUE!
- Dietary intake, nutritional status and energy metabolism in adolescents with severe obesity-Effects of gastric bypass surgery
- Sustained anti-obesity effects of life-style change and anti-inflammatory interventions after conditional inactivation of the activin receptor ALK7
- Impact of n-3 Polyunsaturated Fatty Acids on Adipose Tissue Inflammation and Metabolic Control in Severely Obese Patients
- Exercise-induced adaptations to adipose tissue thermogenesis
- Lack of TRPV 2 impairs thermogenesis in mouse brown adipose tissue
- Trends in research and development of phenolic phytochemicals as potential antidiabetic therapeutics
- Liraglutide and insulin have contrary effects on adipogenesis of human adipose-derived stem cells via wnt pathway
- Linseed oil improves hepatic insulin resistance in obese mice through modulating mitochondrial quality control
- The role of HMGB1 in the pathogenesis of type 2 diabetes
- Antidiabetic, lipid normalizing, and nephroprotective actions of the strawberry: A potent supplementary fruit
- LOSS OF SKELETAL MUSCLE PKCฮธ PROTECTS AGAINST THE PATHOGENESIS OF INSULIN RESISTANCE
- Glucagon-like peptide-2 treatment improves glucose dysmetabolism in mice fed a high-fat diet
- Weight loss management in client-owned horses
- Reduced number of adipose lineage and endothelial cells in epididymal fat in response to omega-3 PUFA in mice fed high-fat diet
- In obese mice, exercise training increases 11ฮฒ-HSD1 expression, contributing to glucocorticoid activation and suppression of pulmonary inflammation
- Harmine induces adipocyte thermogenesis through RAC1-MEK-ERK-CHD4 Axis
- Association of Atp2a1 Rs3888190 Single Nucleotide Polymorphism with Obesity and Allergic Conditions among Utar Kampar Campus Students
- Schistosoma Infection and Schistosoma-Derived Products Modulate the Immune Responses Associated with Protection against Type 2 Diabetes
- Micronutrient supplementation to improve the impact of paternal obesity on subsequent generations
- Saponins from Boussingaultia gracilis prevent obesity and related metabolic impairments in diet-induced obese mice
- Interplay between dietary sugars and fats and insulin resistance
- Inhibition of inflammatory signaling pathways in 3T3โL1 adipocytes by apolipoprotein AโI
- The Role of Christine A Saponins Molecules in the Control of Mild Chronic Inflammation in Obesity Related with Type-II Diabetes Mellitus
- Eosinophil function in adipose tissue is regulated by Krรผppel-like factor 3 (KLF3)
- Type 2 diabetes mellitus: Prevalence and risk factors
- Potent antihyperglycemic and hypoglycemic effect of Tamarix articulata Vahl. in normal and streptozotocin-induced diabetic rats
- Low-intensity exercise in the prevention of cardiac insulin resistance-related inflammation and disturbances in NOS and MMP-9 regulation in fructose-fedย โฆ
- Alterations in niban gene expression as a response to stress conditions in 3T3-L1 adipocytes
- CD8+ T cell/adipocyte inflammatory cross talk and ensuing M1 macrophage polarization are reduced by fish-oil-derived n-3 polyunsaturated fatty acids, in part by aย โฆ
- ฮฒ-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes
- IKK/NF-ฮบB-regulated Inflammatory Pathway in Human Adipocytes: Implication in Subsequent Contribution to Insulin Resistance and Atherosclerosis
- Systems biology will direct vascular-targeted therapy for obesity
- Remodeling of rat stromal-vascular cells to brite/beige adipocytes by prolyl-hydroxyproline
- Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver
- Protein kinase A induces UCP1 expression in specific adipose depots to increase energy expenditure and improve metabolic health
- Omega-3 fatty acids and adipose tissue biology
- Toll-like receptor-4 signaling mediates inflammation and tissue injury in diabetic nephropathy
- THE LONG PENTRAXIN 3 PLAYS A KEY ROLE IN THE IMMUNOMODULATION OF DIET-INDUCED OBESITY
- Protectin DX ameliorates palmitate-or high-fat diet-induced insulin resistance and inflammation through an AMPK-PPARฮฑ-dependent pathway in mice
- Browning of white fat: agents and implications for beige adipose tissue to type 2 diabetes
- Investigation of mechanisms of insulin-regulated lipolysis via ABHD15.
- Effects of vaspin on insulin resistance in rats and underlying mechanisms
- Deficiency of adipocyte IKKฮฒ affects atherosclerotic plaque vulnerability in obese LDLR deficient mice
- 11ฮฒ-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice
- Study on development of brown and beige adipocytes in mice: effect of age and diet-induced obesity
- Celastrol attenuates mitochondrial dysfunction and inflammation in palmitate-mediated insulin resistance in C3A hepatocytes
- Obesity and Type 2 Diabetes Mellitus: Adipocytokines as Markers of Insulin Resistance
- Platelet count and 8-year incidence of diabetes: The Korean Genome and Epidemiology Study
- Association between serum C-reactive protein and serum gamma-glutamyl transferase with type 2 diabetes in the Kuopio Ischaemic Heart Disease Risk Factorย โฆ
- Molecular mechanisms of insulin resistance
- The Adipose Organ: Cold Acclimation
- Exercise, heat shock proteins and insulin resistance
- NLRP3 inflammasome inhibition with MCC950 improves insulin sensitivity and inflammation in a mouse model of frontotemporal dementia
- Micronutrient deficiency, a novel nutritional risk factor for insulin resistance and Syndrom X
- Anti-inflammatory agents in the treatment of diabetes and its vascular complications
- Effect of dietary pretreatment and obesity on (-)-epigallocatechin-3-gallate (EGCG) mediated hepatotoxicity and the underlying mechanism
- Inflammation is not a contributing factor in the development of insulin resistance in diet induced obesity in rats
- Consequences of exposure to maternal diabetes on offspring puberty and adiposity
- Browning and Beiging of Adipose Tissue: Its Role in the Regulation of Energy Homeostasis and as a Potential Target for Alleviating Metabolic Diseasesย โฆ
- Uncoupling Lipid Metabolism from Inflammation in Adipose Tissue
- RESEARCH ON TYPE 2 DIABETES, INSULIN RESISTANCE, AND THE IMMUNE SYSTEM
- Artemisinin mimics nitric oxide to reduce adipose weight by targeting mitochondrial complexes
- #VALUE!
- Dlgap1 negatively regulates browning of white fat cells through effects on cell proliferation and apoptosis
- The interaction between prohibitin-1 and sex steroid hormones in adipogenesis
- Association Between Single Nucleotide Polymorphisms (SNPs) in the Promoter of Adiponectin Gene, Hypoadiponectinemia, and Diabetes
- Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
- Theoretical review: Effect of caffeine intake on food consumption patterns and body weight gain
- A PRDM16-driven metabolic signal from adipocytes regulates precursor cell fate
- HOMA-estimated insulin resistance as an independent prognostic factor in patients with acute pancreatitis
- w Adherence to Weight Loss and Physical Activity
- Transcriptional, Epigenetic and Lipidomic Responses to Metabolic Interventions: Implications for Human Obesity
- Rosiglitazone elicits an adiponectin-mediated insulin-sensitizing action at the adipose tissue-liver axis in Otsuka Long-Evans Tokushima fatty rats
- Repeated ozone exposure exacerbates insulin resistance and activates innate immune response in genetically susceptible mice
- Omega-3 fatty acids as feed supplement modulates blood formation and body weight in Rattus norvegicus model
- MKK6 controls T3-mediated browning of white adipose tissue
- Associations of brain reactivity to food cues with weight loss, protein intake and dietary restraint during the PREVIEW intervention
- IRS proteins and diabetic complications
- Intestinal microbial metabolites in human metabolism and type 2 diabetes
- Leptin Repolarizes Tumor-Associated Macrophages to Boost Immunotherapy Efficacy in Obesity
- Protective effects of Ficus carica leaves on glucose and lipids levels, carbohydrate metabolism enzymes and ฮฒ-cells in type 2 diabetic rats
- Targeted molecular magnetic resonance imaging detects brown adipose tissue with ultrasmall superparamagnetic iron oxide
- #VALUE!
- Diabetes and sepsis: risk, recurrence, and ruination
- Lysine-specific demethylase 1 promotes brown adipose tissue thermogenesis via repressing glucocorticoid activation
- 3,5 Diiodo-l-Thyronine (T2) Promotes the Browning of White Adipose Tissue in High-Fat Diet-Induced Overweight Male Rats Housed at Thermoneutrality
- Cross-talk between adipose tissue health, myocardial metabolism and vascular function: the adipose-myocardial and adipose-vascular axes
- Adipose tissue: Development, physiology, and pathophysiology
- Aptamers: novel diagnostic and therapeutic tools for diabetes mellitus and metabolic diseases
- Flaxseed oil attenuates hepatic steatosis and insulin resistance in mice by rescuing the adaption to ER stress
- Effects of ฮฑ-lipoic acid on lipid metabolism and mitochondrial biogenesis in adipocytes: study of the molecular mechanisms involved
- Bone Morphogenetic Protein 4 regulates white, beige and brown adipose tissue
- Weight management in horses: relationships among digestible energy intake, body weight, and body condition
- Graphical abstract Chapter 3: PEDF-induced alteration of metabolism leading to insulin resistance
- The Effects of Interleukin-10 on Skeletal Muscle Insulin Resistance and Myogenesis
- Duration of aโ Brown-Likeโ Phenotype of White Adipose Tissue Induced by the ฮฒ3 Agonist CL-316,243
- The Anti-Obesogenic Effect of Lean Fish Species Is Influenced by the Fatty Acid Composition in Fish Fillets
- Oxygen-Dependent Regulation of Fatty Acid Metabolism and Endoplasmic Reticulum Function in Adipocytes
- Lowering effects of aspirin eugenol ester on blood lipids in rats with high fat diet
- Fรกrmacos usados no tratamento da dislipidemia e da obesidade: foco no tecido adiposo/Drugs involved in dyslipidemia and obesity treatment: focus onย โฆ
- Exercise training induces depot-specific adaptations to white and brown adipose tissue
- Amelioration of high-insulin-induced skeletal muscle cell insulin resistance by resveratrol is linked to activation of AMPK and restoration of GLUT4 translocation
- New advances in our understanding of the control and functions of brown adipose tissue thermogenesis
- TSH promotes adiposity by inhibiting the browning of white fat
- Association of daily home-based hot water bathing and glycemic control in ambulatory japanese patients with type 2 diabetes mellitus during the COVID-19 pandemicย โฆ
- Serum CXCL2 Level Can Predict High-Fat Diet-Induced Impairment of Bone Marrow Mesenchymal Stem Cells
- Metabolomic response of skeletal muscle to aerobic exercise training in insulin resistant type 1 diabetic rats
- Adipose Sensory Nerves: Functional and Neuroanatomical Evidence for Their Emerging Role in Energy Balance
- #VALUE!
- Small Ubiquitin-Like Modifier 4 (SUMO4) Gene M55V Polymorphism and Type 2 Diabetes Mellitus: A Meta-analysis Including 6,823 Subjects
- The effect of concurrent aerobic and resistance exercises on glucose homeostasis and serum HS-CRP in overweight and obese anxious adolescent girls
- Therapeutic methods against insulin resistance
- Thyroid hormone status defines brown adipose tissue activity and browning of white adipose tissues in mice
- Acute insulin deprivation results in altered mitochondrial substrate sensitivity conducive to greater fatty acid transport
- Low-dose aspirin improves glucose uptake and attenuates inflammation in rats fed high-fat diet
- Panx1 and Panx3 Regulate Adipocyte Development and Fat Accumulation in Vivo
- Mechanisms of action of ginger in nuclear factor-kappaB signaling pathways in diabetes
- Adiposity and Health in Zoo African and Asian Elephants
- The potential roles of artemisinin and its derivatives in the treatment of type 2 diabetes mellitus
- Transgenerational glucose intolerance of tumor necrosis factor with epigenetic alteration in rat perirenal adipose tissue induced by intrauterine hyperglycemia
- PHD3 regulates glucose metabolism by suppressing stress-induced signalling and optimising gluconeogenesis and insulin signalling in hepatocytes
- Role of macrophages in depot-dependent browning of white adipose tissue
- The Effect of Endurance Training on Adiponectin and Insulin Resistance in Overweight Female University Students.
- Fรกrmacos Usados no Tratamento da Dislipidemia e da Obesidade: Foco no Tecido Adiposo
- In Vitro Effects of Oil’s Fatty Acids on T-Cell Function of Obese Men
- Being big, becoming small: conversations with Mฤori women about weight loss surgery: a thesis presented in partial fulfilment of the requirements for the degree ofย โฆ
- #VALUE!
- Food-predicting stimuli differentially influence eye movements and goal-directed behavior in normal-weight, overweight, and obese individuals
- Oxidative stress and diabetes: antioxidative strategies
- Type 2 Diabetes Mellitus Acts as a Risk Factor for the Development of Early Stage Alzheimer’s Disease
- Association between normal triglyceride and insulin resistance in US adults without other risk factors: a cross-sectional study from the US National Health andย โฆ
- Abscisic acid supplementation rescues high fat diet-induced alterations in hippocampal inflammation and IRSs expression
- Astragaloside IV Inhibits Adipose Lipolysis and Reduces Hepatic Glucose Production via Akt Dependent PDE3B Expression in HFD-Fed Mice
- Novel Adipose Tissue Targets to Prevent and Treat Atherosclerosis
- Diabetic cardiomyopathy: an immunometabolic perspective
- Fish and fish oil for cardiovascular disease in diabetes
- Effects of Aspirin on metabolic alterations in Type 2 Diabetic Rats
- Lactational metformin exposure programs offspring white adipose tissue glucose homeostasis and resilience to metabolic stress in a sex-dependent manner
- Interventions for sustainable weight loss in military families
- Preventive effect of salicylate and pyridoxamine on diabetic nephropathy
- HB-EGF and ADAM 12S directed cellular reprogramming results in metabolically active brown adipose tissue-like cells
- Molecular remodeling of the insulin receptor pathway by thiazolidinediones in type 2 diabetes mellitus: A brief review
- CD24 is required for gene expression, but not glucose uptake, during adipogenesis in vitro
- A novel small molecule A2A adenosine receptor agonist, indirubin-3โฒ-monoxime, alleviates lipid-induced inflammation and insulin resistance in 3T3-L1 adipocytes
- Oral treatment with a zinc complex of acetylsalicylic acid prevents diabetic cardiomyopathy in a rat model of type-2 diabetes: activation of the Akt pathway
- Monocyte Factors in Pathogenesis of Vascular Lesions in Diabetes
- Transcriptome sequencing analysis of peripheral blood of type 2 diabetes mellitus patients with thirst and fatigue
- A dietary anthocyanin cyanidin-3-O-glucoside binds to PPARs to regulate glucose metabolism and insulin sensitivity in mice
- TO STUDY THE EFFECT OF LAPAROSCOPIC SLEEVE GASTRECTOMY ON BMI AND METABOLIC PARAMETERS IN MORBIDLY OBESE PATIENTS.
- Metabolic pathways at the crossroads of diabetes and inborn errors
- Glycosaminoglycan from Apostichopus japonicus Improves Glucose Metabolism in the Liver of Insulin Resistant Mice
- Siglec-7 restores ฮฒ-cell function and survival and reduces inflammation in pancreatic islets from patients with diabetes
- Associations between anthropometric traits, detailed body composition, fat fraction per adipose tissue and cardiometabolic risks: differences between childrenย โฆ
- Anti-TNF-ฮฑ antibody alleviates insulin resistance in rats with sepsis-induced stress hyperglycemia
- CIDEA transcriptionally regulates UCP1 for britening and thermogenesis in human fat cells
- Co-expression of HB-EGF and ADAM 12S displays a brown adipose phenotype in mouse and human cell lines.
- Phosphorylation of the exocyst protein Exo84 by TBK1 promotes insulin-stimulated GLUT4 trafficking
- Effects of sodium salicylate on glucose kinetics and insulin signaling in postpartum dairy cows
- Metabolic syndrome, brain insulin resistance, and Alzheimer’s disease: Thioredoxin Interacting Protein (TXNIP) and inflammasome as core amplifiers
- Retinoid X receptor ligands with anti-type 2 diabetic activity
- Complementary cholesterol-lowering response of a phytosterol/ฮฑ-lipoic acid combination in obese zucker rats
- Immunoglobulin free light chains: An inflammatory biomarker of diabetes
- The Origin of Human White, Brown, and Brite/Beige Adipocytes
- Passive heating and glycaemic control in non-diabetic and diabetic individuals: A systematic review and meta-analysis
- Angiogenic factors in the white adipose tissue in childhood
- Association between fat mass, adipose tissue, fat fraction per adipose tissue, and metabolic risks: a cross-sectional study in normal, overweight, and obese adults
- The Serum Level of KL-6 Is Associated with the Risk of Insulin Resistance and New-onset Diabetes Mellitus: The Tanno-Sobetsu Study
- Proinflammatory cytokine polarization in type 2 diabetes
- Phenotypic characterization of a novel Ucp1-LUC-iRFP713 reporter mouse model for visualization and quantification of brown and beige fat recruitment
- Effect of metabolic syndrome on fertility of male type 2 diabetic mice
- Alpha-lipoic acid preserves skeletal muscle mass in type 2 diabetic OLETF rats
- Graphical abstract Chapter 2: Molecular aspects of glucose homeostasis in skeletal muscleโA focus on the molecular mechanisms of insulin resistance
- XENOGRAFT OF MICROENCAPSULATED SERTOLI CELLS RESTORES GLUCOSE HOMEOSTASIS IN db/db MICE WITH SPONTANEOUS DIABETESย โฆ
- The Immune Deficiency Pathway Attenuates Insulin Signaling to Protect Against Infection.
- Alpha-lipoic acid alleviates acute inflammation and promotes lipid mobilization during the inflammatory response in white adipose tissue of mice
- Normal Triglyceride is Associated with Insulin Resistance in the Absence of Risk Factors
- Evidence-based psychotherapeutic interventions and mhealth for weight management in overweight: A biopsychosocial framework
- The Development and Feasibility of a Culturally Tailored Malaysian Diabetes Education Intervention Using Motivational Interviewing (MY DEUMI) for Peopleย โฆ
- Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway
- Sub-toxic exposure to lindane activates redox sensitive kinases and impairs insulin signaling in muscle cell culture: the possible mechanism of lindane-inducedย โฆ
- Electrochemolipolysis of human adipose tissue
- Inhibition of Free fatty acid-Induced Insulin Resistance by Rosemary Extract: Investigation of the Mechanisms Involved
- W2476 ameliorates ฮฒ-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting proteinย โฆ
- Effect of sub-toxic chlorpyrifos on redox sensitive kinases and insulin signaling in rat L6 myotubes
- Mutation in Sortilin Identified in an Amish Population Results in Hypercholesterolemia and Insulin Resistance in Mice and Humans
- A Role for TNMD in Adipocyte Differentiation and Adipose Tissue Function: A Dissertation
- Insulin Resistance and T1D: The Effect of Exercise on Skeletal Muscle Lipid Metabolism
- Immunoglobulin Free Light Chains: A Biomarker of Diabetes
- Omega-3 fatty acid supplementation combined with acute aerobic exercise does not alter the improved post-exercise insulin response in normoglycemic, inactive andย โฆ
- The effect of the aerobic continues versus high-intensity interval training on IRE1 expression and its correlation with insulin resistance index of liver tissue in ratsย โฆ
- Synthetic salicylates and/or pioglitazone ameliorative effect in type 2 induced diabetic rats
- Flavonoid-enriched extract from desert plant Warionia saharae improves glucose and cholesterol levels in diabetic rats
- Improvement of insulin signalling rescues inflammatory cardiac dysfunction
- Evaluation of glucose and lipid lowering activity of Arganimide A in normal and streptozotocin-induced diabetic rats
- Antidiabetic effect of spearmint in streptozotocin-induced diabetic rats
- Aqueous extract of Argania spinosa L. fruits ameliorates diabetes in streptozotocin-induced diabetic rats
- Insulin plant (Costus pictus) extract restores thyroid hormone levels in experimental hypothyroidism
- Advances in antidiabetic drugs targeting insulin secretion
- The Effects of Resistance and Aerobic Training Volume on Body Composition and Adipokines
- #VALUE!
- Clinical decision-making when treating diabetic macular edema patients with dexamethasone intravitreal implants
- Metformin alleviates neuronal and renal related stress signals in diabetic C57BL/6 mice.
- Sustained NFjB inhibition improves insulin sensitivity but is detrimental to muscle health
- Reversal of obesity development in Ceacam1โ/โ male mice by bone marrow transplantation or introduction of the human CEACAM1 gene
- White adipocyte-targeted dual gene silencing of FABP4/5 for anti-obesity, anti-inflammation and reversal of insulin resistance: Efficacy and comparison ofย โฆ
- Association of a self-paid medically supervised weight management program with reversal of obesity-associated impaired fasting glucose
- Reciprocal control of obesity and anxietyโdepressive disorder via a GABA and serotonin neural circuit
- Loss of function of renal Glut2 reverses hyperglycaemia and normalises body weight in mouse models of diabetes and obesity
- Trends in US adolescent physical activity and obesity: A 20โyear ageโperiodโcohort analysis
- Reversal of hypertriglyceridemia in diabetic BTBR ob/ob mice does not prevent nephropathy
- FACI Is a Novel CREB-HโInduced Protein That Inhibits Intestinal Lipid Absorption and Reverses Diet-Induced Obesity
- Swertiamarin ameliorates diet-induced obesity by promoting adipose tissue browning and oxidative metabolism in preexisting obese mice: Swertiamarinย โฆ
- Obesity and chronic diarrhea: a new syndrome?
- Peripheral blood mononuclear cells oxidative stress and plasma inflammatory biomarkers in adults with normal weight, overweight and obesity
- Whole-food plant-based lifestyle program and decreased obesity
- A Novel Symbiotic Formulation Reduces Obesity and Concomitant Metabolic Syndrome in Rats by Raising the Relative Abundance of Blautia
- Dieting reverses histone methylation and hypothalamic AgRP regulation in obese rats
- Effectiveness of a populationโscaled, schoolโbased physical activity intervention for the prevention of childhood obesity
- Allograft inflammatory factor-1-like is a situational regulator of leptin levels, hyperphagia, and obesity
- Essential Oil of Carvone Chemotype Lippia alba (Verbenaceae) Regulates Lipid Mobilization and Adipogenesis in Adipocytes
- Reversing the genomic, epigenetic, and triple-negative breast cancerโenhancing effects of obesity
- The impact of weight cycling on health outcomes in animal models: A systematic review and metaโanalysis
- Metformin booster adipocyte-targeted gene therapy for the treatment of obesity and related metabolic syndromes
- Obesity as a major health hazard
- 233-LB: Ranolazine Fails to Improve Glycemia in Obese Liver-Specific Pyruvate DehydrogenaseโDeficient Mice
- Mechanism of action of acupuncture in obesity: a perspective from the hypothalamus
- AAV-mediated BMP7 gene therapy counteracts insulin resistance and obesity
- Precision nutrition, diet and gut-microbiota in obesity
- Brown and beige adipose tissue: a novel therapeutic strategy for obesity and type 2 diabetes mellitus
- Nanotechnology-Based Strategies for Treatment of Obesity, Cancer and Anti-microbial Resistance: Highlights of the Department of Science and Innovation/Mintekย โฆ
- Fetal programming of obesity and type 2 diabetes
- The insulin-sensitizer pioglitazone remodels adipose tissue phospholipids in humans
- Association between visceral obesity, metformin use, and recurrence risk in early-stage colorectal cancer
- Biomaterial-based therapeutic strategies for obesity and its comorbidities
- Obesity and metabolic syndrome in atrial fibrillation: cardiac and noncardiac adipose tissue in atrial fibrillation
- Impact of Surgical and Dietary Weight Loss Interventions on the ObesityโGut MicrobiomeโBreast Cancer Links
- The Effects of Obesity and Bariatric Surgery on Rates of Upper Extremity Compression Neuropathies
- Revised Protein Sparing Diet in Obesity and Type 2 Diabetes Mellitus
- Stress granules determine the development of obesity-associated pancreatic cancer
- The tumor promotional role of adipocytes in the breast cancer microenvironment and macroenvironment
- Two-year skeletal effects of sleeve gastrectomy in adolescents with obesity assessed with quantitative CT and MR spectroscopy
- Obesity, an independent predictor of pre and postoperative tumor grading disagreement in endometrial cancer
- The anti-obesity effect of Allium cepa L. leaves on high fat diet induced obesity in male wistar rats
- Turning the clock forward: New pharmacological and non pharmacological targets for the treatment of obesity
- Association between socioeconomic positions and overweight/obesity in rural Nepal
- Impact of digital monitoring on compliance and outcome of lifestyle-change measures in patients with coexistent atrial fibrillation and obesity
- Obesity and dyslipidemia are associated with partially reversible modifications to DNA hydroxymethylation of apoptosis-and senescence-related genes inย โฆ
- Tumor suppressor Par-4 regulates complement factor C3 and obesity
- Obesity Hypertension: Clinical Aspects
- Skeletal muscle non-shivering thermogenesis as an attractive strategy to combat obesity
- Characterization of Allograft Inflammatory Factor-1-Like (AIF1L) in Diet-Induced Obesity
- A novel dual-targeted rosiglitazone-loaded nanoparticle for the prevention of diet-induced obesity via the browning of white adipose tissue
- Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer
- Obesity and bariatric surgery in kidney transplantation: a clinical review
- Weight loss and/or sulindac mitigate obesity-associated transcriptome, microbiome, and protumor effects in a murine model of colon cancer
- Are individual or group interventions more effective for longโterm weight loss in adults with obesity? A systematic review
- The impact of school-based physical activity programs on obesity prevention
- The potential mechanisms of white adipose tissue browning: a novel target for the treatment of obesity.
- Sacubitril/valsartan inhibits obesity-associated diastolic dysfunction through suppression of ventricular-vascular stiffness
- Childhood overweight and obesity abatement policies in Europe
- Cyclin-dependent kinase 4/6 inhibitors require an arcuate-to-paraventricular hypothalamus melanocortin circuit to treat diet-induced obesity
- Brown adipose tissue in adults as a study target in the development of new therapies for the management and treatment of obesity: an integrative review
- The gut microbiota as a therapeutic target for obesity: a scoping review
- Longitudinal gut microbial signals are associated with weight loss: insights from a digital therapeutics program
- Actin related protein 2/3 complex subunit 1 upโregulation in the hypothalamus prevents highโfat diet induced obesity
- Association between distinct body mass index trajectories according to the groupโbased trajectory modeling and the risk of incident diabetes: A systematic review
- Epicardial adipose tissue, obesity, and the occurrence of atrial fibrillation: an overview of pathophysiology and treatment methods
- MPA alters metabolic phenotype of endometrial cancer-associated fibroblasts from obese women via IRS2 signaling
- Gastrokine-1, an anti-amyloidogenic protein secreted by the stomach, regulates diet-induced obesity
- Role of obesity-induced inflammation in the development of insulin resistance and type 2 diabetes: History of the research and remaining questions
- Adipose-targeted triiodothyronine therapy counteracts obesity-related metabolic complications and atherosclerosis with negligible side effects
- Obese adipose tissue as a driver of breast cancer growth and development: Update and emerging evidence
- Characteristic MicroRNAs linked to dysregulated metabolic pathways in qatari adult subjects with obesity and metabolic syndrome
- Crosstalk between Melanin Concentrating Hormone and Endocrine Factors: Implications for Obesity
- Combining a ฮฒ3 adrenergic receptor agonist with alphaโlipoic acid reduces inflammation in male mice with dietโinduced obesity
- Regulation of body weight: lessons learned from bariatric surgery
- An overview of epigenetics in obesity: The role of lifestyle and therapeutic interventions
- Lycopene alleviates ionic disturbances and anaemia by improving iron homeostasis, insulin sensitivity, and ATPases activities in obese female rats
- Deciphering biochemical and molecular signatures associated with obesity in context of metabolic health
- Gintonin-enriched fraction protects against sarcopenic obesity by promoting energy expenditure and attenuating skeletal muscle atrophy in high-fat diet-fedย โฆ
- Neuroimaging Investigations of Obesity: a Review of the Treatment of Sex from 2010
- Evaluation of a group family-based intervention programme for adolescent obesity: the LITE randomised controlled pilot trial
- Investigation of the anti-obesity effects of citrate-capped gold nanoparticles on 3T3-L1 cells and their genetic profiling
- Zebrafish and flavonoids: adjuvants against obesity
- The role of the gut microbiome in pediatric obesity and bariatric surgery
- Lycopene abrogates obesity-provoked hyperactivity of neurosignalling enzymes, oxidative stress and hypothalamic inflammation in female Wistar rats
- Diet-derived antioxidants and their role in inflammation, obesity and gut microbiota modulation
- Enhancing fatty acids oxidation via l-carnitine attenuates obesity-related atrial fibrillation and structural remodeling by activating AMPK signaling andย โฆ
- Role of obesity related inflammation in pathogenesis of peripheral artery disease in patients of type 2 diabetes mellitus
- Potential therapeutic effect of medium chain triglyceride oil in ameliorating diabetic liver injury in a streptozotocin-induced diabetic murine model.
- New insights into adipose tissue macrophages in obesity and insulin resistance
- Injectable cell-targeting fiber rods to promote lipolysis and inflammatory regulation for obesity treatment
- Obesity and altered angiogenic-related gene expression in endometrial cancer
- Photoacoustic molecular imaging-escorted adipose photodynamicโbrowning synergy for fighting obesity with virus-like complexes
- Macrophage membrane-camouflaged lipoprotein nanoparticles for effective obesity treatment based on a sustainable self-reinforcement strategy
- Involvement of TRP channels in adipocyte thermogenesis: An update
- Improved outcomes in rheumatoid arthritis with obesity after a weight loss intervention: randomized trial
- Does obesity put your brain at risk?
- Transdermal photothermal-pharmacotherapy to remodel adipose tissue for obesity and metabolic disorders
- Perillartine protects against metabolic associated fatty liver in high-fat diet-induced obese mice
- The impacts of exercise on pediatric obesity
- Neural vulnerability factors that predict future weight gain
- #VALUE!
- CREG1 administration stimulates BAT thermogenesis and improves diet-induced obesity in mice
- 4-Hydroxyisoleucine alleviates macrophage-related chronic inflammation and metabolic syndrome in mice fed a high-fat diet
- Outcome of mini gastric bypass after failed vertical band gastroplasty in treatment of morbid obese patients
- Circulating acyl and des-acyl ghrelin levels in obese adults: a systematic review and meta-analysis
- Transcriptome sequencing of 3, 3โฒ, 4, 4โฒ, 5-Pentachlorobiphenyl (PCB126)-treated human preadipocytes demonstrates progressive changes in pathwaysย โฆ
- Metformin Mitigated Obesity-Driven Cancer Aggressiveness in Tumor-Bearing Mice
- Hepatokine Fetuin B expression is regulated by leptin-STAT3 signalling and associated with leptin in obesity
- Adipose endothelial cells mastering adipose tissues metabolic fate
- Immune checkpoint blockade reprograms systemic immune landscape and tumor microenvironment in obesity-associated breast cancer
- Effects of Obesogenic Environment on Body Weight Regulation: A Review
- The physiologic and physiopathologic roles of perivascular adipose tissue and its interactions with blood vessels and the renin-angiotensin system
- Liraglutide suppresses obesity and promotes browning of white fat via miR-27b in vivo and in vitro
- Cell death and inflammation during obesity:โKnow my methods, WAT (son)โ
- Adipokines, myokines, and hepatokines: crosstalk and metabolic repercussions
- Positive effect of combined exercise on adipokines levels and pubertal signs in overweight and obese girls with central precocious puberty
- Obesity as a premature aging phenotypeโImplications for sarcopenic obesity
- Astragalus mongholicus powder, a traditional Chinese medicine formula ameliorate type 2 diabetes by regulating adipoinsular axis in diabetic mice
- N-Trimethylated chitosan coating white adipose tissue vascular-targeting oral nano-system for the enhanced anti-obesity effects of celastrol
- Optogenetic activation of UCP1-dependent thermogenesis in brown adipocytes
- Piecing together human adult comparative pharmacokinetic trials and rodent studies: What happens to drug clearance in obesity?
- Caloric restriction overcomes pre-diabetes and hypertension induced by a high fat diet and renal artery stenosis
- Interleukin-1 in obesity-related low-grade inflammation: From molecular mechanisms to therapeutic strategies
- Obesity Is Associated with Immunometabolic Changes in Adipose Tissue That May Drive Treatment Resistance in Breast Cancer: Immune-Metabolic Reprogrammingย โฆ
- Insulin and insulin-like growth factor-1 associated cancers
- Macrophages, chronic inflammation, and insulin resistance
- Brown/Beige Adipose Tissue: Novel Players in the Fight Against Obesity
- 3-N-butylphthalide protects against high-fat-diet-induced obesity in C57BL/6 mice and increases metabolism in lipid-accumulating cells
- The effect of healthy lifestyle strategies on the management of insulin resistance in children and adolescents with obesity: a narrative review
- Next generation GLP-1/GIP/glucagon triple agonists normalize body weight in obese mice
- Deletion of the feeding-induced hepatokine TSK ameliorates the melanocortin obesity syndrome
- Understanding Pericardial Adipose Tissue Mitochondrial Bioenergetics in the Context of Obesity
- Adipocyte IRE1ฮฑ promotes PGC1ฮฑ mRNA decay and restrains adaptive thermogenesis
- Induction of lipid catabolism and mitochondrial biogenesis in white adipose tissue as therapeutic target for obesity and associated metabolic disorders
- Functionalized nanoformulation based on enriched-triterpenes fraction target adipose tissue, as a potential treatment to obesity and type-2 diabetes: preliminary data
- Gut Microbiota Modulation and Its Relationship with Obesity Using Prebiotic Fibers and Probiotics: A
- Adipocyte phenotype flexibility and lipid dysregulation
- Revisiting the contribution of mitochondrial biology to the pathophysiology of skeletal muscle insulin resistance
- Revisiting the Principles of Preservation in an Era of Pandemic Obesity
- Progress toward molecular therapy for diabetes mellitus: a focus on targeting inflammatory factors
- Non-alcoholic fatty liver disease: the interplay between metabolism, microbes and immunity
- Prohibitin inactivation in adipocytes results in reduced lipid metabolism and adaptive thermogenesis impairment
- Is overweight still a problem of rich in sub-Saharan Africa? Insights based on female-oriented demographic and health surveys
- #VALUE!
- Genetic advancements in obesity management and CRISPRโCas9-based gene editing system
- Brain regulation of hunger and motivation: The case for integrating homeostatic and hedonic concepts and its implications for obesity and addiction
- Sodium salicylate rewires hepatic metabolic pathways in obesity and attenuates IL-1ฮฒ secretion from adipose tissue: The implications for obesity-impairedย โฆ
- Role of insulin resistance in MAFLD
- Antidiabetic and Antioxidant Activity of Zanthoxylum armatum DC. On Type 2 Diabetic Rats.(2022)
- New Insights into Adipose Tissue Macrophages in Obesity and Insulin Resistance. Cells 2022, 11, 1424
- Regenerative Medicine for Polycystic Ovary Syndrome: Stem Cell-Based Therapies and Brown Adipose Tissue Activation
- Obesity and Hepatocellular Carcinoma: Epidemiology and Mechanisms
- Impact of inflammasome inhibition on the development of insulin
- Jean Himms-Hagen, D. Phil.(1933โ2021): Pioneering research in brown adipose tissue thermogenesis
- Excessive weight gain and poor growth
- Durability of changes in biomarkers of cardiometabolic disease: 1-year family-based intervention in children with obesity
- Inhibition of LIFR Blocks Adiposity-Driven Endometrioid Endometrial Cancer Growth
- REDD1 promotes obesity-induced metabolic dysfunction via atypical NF-ฮบB activation
- Inflammatory Mediators and Type 2 Diabetes Risk Factors before and in Response to Lifestyle Intervention among Latino Adolescents with Obesity
- Cissus Quadrangularis enhances UCP1 mRNA, indicative of white adipocyte browning and decreases central obesity in humans in a randomized trial
- Uncoupling hepatic insulin resistanceโhepatic inflammation to improve insulin sensitivity and to prevent impaired metabolism-associated fatty liver disease inย โฆ
- Effect of 8-Week Short-Term Sprint Interval Training on Serum Levels of Adipokines, Inflammatory Markers and Lipid Profile in Overweight Boys
- Obesity protects against sepsis-induced and norepinephrine-induced white adipose tissue browning
- What Happens to Adipokines and Cytokine in Overweight and Obese Girls with Central Precocious Puberty When They Exercise and Stop Exercising? A randomizedย โฆ
- Evaluation of serum irisin, retinol-binding protein-4 in human obesity
- Browning epicardial adipose tissue: friend or foe?
- The adipose organ is a unitary structure in mice and humans
- Epigallocatechin gallate decreases plasma triglyceride, blood pressure, and serum kisspeptin in obese human subjects
- Thermoregulatory responses, heart rate, and the susceptibility to anxiety in obese animals subjected to stress
- Endothelial TrkA coordinates vascularization and innervation in thermogenic adipose tissue and can be targeted to control metabolism
- Sodium salicylate induces browning of white adipocytes via M2 macrophage polarization by HO-1 upregulation
- Obesity Induced Insulin Resistance, Type 2 Diabetes and Emerging Therapeutic Approaches
- Deoxysphingolipids โ atypical skeletal muscle lipids related to insulin resistance in humans that decrease insulin sensitivity in vitro
- Effect of 8-weeks of Combined Exercise Training on Plasma Leptin and Adiponectin levels in Obese Boys
- The Influence of Aerobic Exercise on Extracellular Vesicles in Obesity
- Peptide Adjuvant to Invigorate Cytolytic Activity of NK Cells in an Obese Mouse Cancer Model
- Endothelial prohibitin mediates bidirectional long-chain fatty acid transport in white and brown adipose tissues
- Healthy for My Baby Research Protocol-a Randomized Controlled Trial Assessing a Preconception Intervention to Improve the Lifestyle of Overweight Womenย โฆ
- Effects of N-3 PUFA-Derived Epoxides Combined with sEH Inhibition on Brown Adipose Tissue and Brown Adipocytes in Obesity
- Eicosapentaenoic Acid Ethyl Esters Prevent Obesity Associated Metabolic Impairments in Male and Female Mice
- Weight Loss Strategies
- Mechanisms of Action of Berry Bioactives on Obesity-induced Inflammation
- Research Article Regulation of UCP1 in the Browning of Epididymal Adipose Tissue by ๐ฝ3-Adrenergic Agonist: A Role for MicroRNAs
- Adiposeโspecific ATGL ablation reduces burn injuryโinduced metabolic derangements in mice
- #VALUE!
- Deconstructing adipose tissue heterogeneity one cell at a time
- Manipulation of growth conditions of cyanobacteria to potentiate the production of high value compounds for obesity treatment
- Application in medicine: obesity and satiety control
- The Role of Catechins in Regulating Diabetes: An Update Review
- Tissue-specific insulin sensitivity and changes in brain reward reactivity in overweight or obese pre-diabetic adults
- Linseed oil supplementation improves altered lipid metabolism and insulin resistance in induced obese rats
- Use of DREADD technology to identify novel targets for antidiabetic drugs
- Salicylate Sodium Suppresses Monocyte Chemoattractant Protein-1 Production by Directly Inhibiting Phosphodiesterase 3B in TNF-ฮฑ-Stimulated Adipocytes
- Factors associated with choice of behavioural weight loss program by adults with obesity
- Impact of inflammasome inhibition on the development of insulin resistance in the context of diet-induced obesity
- Principal predictors of major adverse limb events in diabetic peripheral artery disease: A narrative review
- Sandalwood seed oil ameliorates hepatic insulin resistance by regulating the JNK/NF-ฮบB inflammatory and PI3K/AKT insulin signaling pathways
- Browning and Beiging of Adipose Tissue: Its Role in the Regulation of Energy Homeostasis and as a Potential Target for Alleviating Metabolic Diseasesย โฆ
- Effects of ADIPOQ Gene Polymorphisms on Combined Training-induced Weight Loss of Obese Boys
- Children With Asparaginase-associated Pancreatitis Present Elevated Levels of Insulin, Total Cholesterol, and HOMA-IR Before Starting Acute Lymphoblasticย โฆ
- Insulin resistance and cancer: In search for a causal link
- Development of predictive models for successful weight loss in people living with obesity
- High-throughput mediation analysis of human proteome and metabolome identifies mediators of post-bariatric surgical diabetes control
- White adipose tissue depots respond to chronic beta-3 adrenergic receptor activation in a sexually dimorphic and depot divergent manner
- Somatic ablation of IKKฮฒ in liver and leukocytes is not tolerated in obese mice but hepatic IKKฮฒ deletion improves fatty liver and insulin sensitivity
- Diabetes and Hypertension Prevention in Vanuatu: A Community Service Project
- Links between insulin resistance and periodontal bacteria: Insights on molecular players and therapeutic potential of polyphenols
- The ฮฒ3 adrenergic receptor agonist CL316243 ameliorates the metabolic abnormalities of high-fat diet-fed rats by activating AMPK/PGC-1ฮฑ signaling in skeletalย โฆ
- The crucial role and mechanism of insulin resistance in metabolic disease
- Anthocyanins as promising molecules affecting energy homeostasis, inflammation, and gut microbiota in type 2 diabetes with special reference to impact of acylation
- Divergence of Chemerin Reduction by an ATS9R Nanoparticle Targeting Adipose Tissue In Vitro vs. In Vivo in the Rat
- Adiponectin synthesis, secretion and extravasation from circulation to interstitial space
- Apolipoprotein A-IV reduced metabolic inflammation in white adipose tissue by inhibiting IKK and JNK signaling in adipocytes
- Repurposing lenvatinib as a potential therapeutic agent against thyroid eye disease by suppressing adipogenesis in orbital adipose tissues
- Effects of a high-fat diet and global aryl hydrocarbon receptor deficiency on energy balance and liver retinoid status in male Sprague-Dawley rats
- Regulatory modules of human thermogenic adipocytes: functional genomics of large cohort and Meta-analysis derived marker-genes
- Endothelial cells induced progenitors into Brown fat to reduce atherosclerosis
- Calcium-deficiency during pregnancy affects insulin resistance in offspring
- Novel biomarkers of inflammation for the management of diabetes: immunoglobulin-free light chains
- Diabetes as a potential compounding factor in COVID-19-mediated male subfertility
- Altered glucose-dependent secretion of glucagon and ACTH is associated with insulin resistance, assessed by population analysis
- A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthyย โฆ
- Insulin resistance in children and adolescents: mechanisms and clinical effects
- Glucagon shows higher sensitivity than insulin to grapeseed proanthocyanidin extract (GSPE) treatment in cafeteria-fed rats
- Effects of anti-inflammatory therapies on glycemic control in type 2 diabetes mellitus
- Effects of a Diabetes Prevention Program among Latino Youth with Prediabetes
- Emerging roles of myeloid-derived suppressor cells in diabetes
- Characterization of peptides targeting metastatic tumor cells as probes for cancer detection and vehicles for therapy delivery
- Changes in protein expression due to metformin treatment and hyperinsulinemia in a human endometrial cancer cell line
- Role of mitochondria-associated endoplasmic reticulum membranes in insulin sensitivity, energy metabolism, and contraction of skeletal muscle
- Decreased glucocorticoid signaling potentiates lipid-induced inflammation and contributes to insulin resistance in the skeletal muscle of fructose-fed male ratsย โฆ
- Hypolipidemic and insulin sensitizing effects of salsalate beyond suppressing inflammation in a prediabetic rat model
- Suppression of estrogen receptor beta classical genomic activity enhances systemic and adipose-specific response to chronic beta-3 adrenergic receptorย โฆ
- Orexin receptor type 2 agonism inhibits thermogenesis in brown adipose tissue by attenuating afferent innervation
- Berberine improves TNF-ฮฑ-induced hepatic insulin resistance by targeting MEKK1/MEK pathway
- Studies on Genotype-Phenotype Correlation in Type II Diabetics and Evaluation of Melatonin and DPP-IV inhibitor on Experimental Diabetic Models
- Glucagon Shows Higher Sensitivity than Insulin to Grapeseed Proanthocyanidin Extract (GSPE) Treatment in Cafeteria-Fed Rats. Nutrients 2021, 13, 1084
- Anti-and non-tumor necrosis factor-ฮฑ-targeted therapies effects on insulin resistance in rheumatoid arthritis, psoriatic arthritis and ankylosing spondylitis
- CXCL2 impairs functions of bone marrow mesenchymal stem cells and can serve as a serum marker in high-fat diet-fed rats
- A simple liking survey captures behaviors associated with weight loss in a worksite program among women at risk of type 2 diabetes
- Insights on the role of anti-inflammatory and immunosuppressive agents in the amelioration of diabetes
- Insights into the development of insulin resistance: Unraveling the interaction of physical inactivity, lipid metabolism and mitochondrial biology
- Plant Protein Consumption and Risk of Type 2 Diabetes: A Systematic Review and Meta-Analysis
- Expatiating the molecular approaches of HMGB1 in diabetes mellitus: Highlighting signalling pathways via RAGE and TLRs
- Ursolic acid ameliorates adipose tissue insulin resistance in aged rats via activating the Aktโglucose transporter 4 signaling pathway and inhibitingย โฆ
- Effects of 8 Weeks of Combined Rehabilitation Training on Plasma Levels of Leptin, Adiponectin, and Resistin
- The Impact of Exercise on Serum Levels of Leptin and Adiponectin in Obese Children and Adolescents: A Systematic Review and Meta-Analysis
- The Importance of Education in the Management of Diabetes
- Genistein enhances NAD+ biosynthesis by binding to Prohibitin 1 and upregulating nicotinamide phosphoribosyltransferase in adipocytes
- The Antidiabetic Activities of Neocryptotanshinone: Screened by Molecular Docking and Related to the Modulation of PTP1B
- A randomized placebo-controlled cross-over study on the effects of anthocyanins on inflammatory and metabolic responses to a high-fat meal in healthy subjects.
- The Unity of Redox and Structural Remodeling of Brown Adipose Tissue in Hypothyroidism. Antioxidants 2021, 10, 591
- Critical material designs for mucus-and mucosa-penetrating oral insulin nanoparticle development
- Effects of Korean Food-based Dietary Inflammatory Index Potential on the incidence of diabetes and HbA1c level in Korean adults aged 40 years and older
- NLRP3 inflammasome blocked the glycolytic pathway via targeting to PKLR in arsenic-induced hepatic insulin resistance
- Recent Advances in Molecular Mechanism of Metformin against Gastrointestinal Cancer in Type 2 Diabetics
- Novel Muscle-Homing Peptide FGF1 Conjugate Based on AlphaFold for Type 2 Diabetes Mellitus
