INSULIN ANTILIPOLYTIC (PREVENTS FAT LOSS)
December 8, 2023NUTRIENT SENSING
December 8, 2023
- Thiazolidinediones
- Nonhypoglycemic effects of thiazolidinediones
- Thiazolidinediones
- Thiazolidinediones: an update
- The mode of action of thiazolidinediones
- Metabolic and additional vascular effects of thiazolidinediones
- Thiazolidinediones in the treatment of insulin resistance and type II diabetes
- How safe is the use of thiazolidinediones in clinical practice?
- Unraveling the mechanism of action of thiazolidinediones
- Insulin resistance and its treatment by thiazolidinediones.
- A meta-analysis comparing the effect of thiazolidinediones on cardiovascular risk factors
- Use of thiazolidinediones and fracture risk
- Thiazolidinediones as anti-cancer agents
- Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence
- Effect of thiazolidinediones on body weight in patients with diabetes mellitus
- Thiazolidinediones and fractures in men and women
- Thiazolidinediones: a new class of antidiabetic drugs
- Thiazolidinediones and liver toxicity.
- Protection of the kidney by thiazolidinediones: an assessment from bench to bedside
- Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis
- Thiazolidinediones: a 2010 perspective
- Thiazolidinediones: effects on insulin resistance and the cardiovascular system
- Thiazolidinediones and cardiovascular outcomes in older patients with diabetes
- Pleiotropic effects of thiazolidinediones
- The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones
- Hepatotoxicity with thiazolidinediones: is it a class effect?
- Hepatotoxicity of the thiazolidinediones
- Thiazolidinediones-mechanisms of action
- Thiazolidinediones and blood lipids in type 2 diabetes
- Thiazolidinediones and heart failure: a teleo-analysis
- Thiazolidinediones: metabolic actions in vitro
- Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes
- The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects
- Thiazolidinediones and inflammation
- Mechanisms by which thiazolidinediones enhance insulin action
- Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies
- The safety of thiazolidinediones
- Considerations for management of fluid dynamic issues associated with thiazolidinediones
- Effect of thiazolidinediones on albuminuria and proteinuria in diabetes: a meta-analysis
- Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study
- Hepatotoxicity of thiazolidinediones
- Thiazolidinediones and the risk of edema: a meta-analysis
- Thiazolidinediones: a comparative review of approved uses
- Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes
- Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells
- Thiazolidinediones, peripheral edema, and type 2 diabetes: incidence, pathophysiology, and clinical implications
- Thiazolidinediones improve β-cell function in type 2 diabetic patients
- The effect of thiazolidinediones on BMD and osteoporosis
- Thiazolidinediones for the treatment of type 2 diabetes
- Visfatin is an adipokine, but it is not regulated by thiazolidinediones
- Pharmacokinetic interactions with thiazolidinediones
- Thiazolidinediones and fractures: evidence from translating research into action for diabetes
- Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones
- Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling.
- Thiazolidinediones as anti‐inflammatory and anti‐atherogenic agents
- Thiazolidinediones: the case for early use
- PPARγ-independent antitumor effects of thiazolidinediones
- The role of thiazolidinediones in non-alcoholic steatohepatitis–a systematic review and meta analysis
- New drugs for the treatment of diabetes mellitus: part I: Thiazolidinediones and their evolving cardiovascular implications
- Thiazolidinediones–some recent developments
- Thiazolidinediones, insulin resistance and obesity: finding a balance
- Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity
- Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues
- Mechanisms and clinical effects of thiazolidinediones
- Effectiveness and side effects of thiazolidinediones for type 2 diabetes: real‐life experience from a tertiary hospital
- Antidiabetic thiazolidinediones inhibit leptin (ob) gene expression in 3T3-L1 adipocytes.
- Thiazolidinediones: a plethro of biological load
- Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study
- Muscle-specific PPARγ-deficient mice develop increased adiposity and insulin resistance but respond to thiazolidinediones
- Effects of thiazolidinediones on bone loss and fracture
- Second-generation thiazolidinediones and hepatotoxicity
- Recent findings concerning thiazolidinediones in the treatment of diabetes
- Thiazolidinediones and heart failure
- Thiazolidinediones and the liver in humans
- Bone loss in diabetes: use of antidiabetic thiazolidinediones and secondary osteoporosis
- Thiazolidinediones today
- Effects of thiazolidinediones on differentiation, proliferation, and apoptosis
- A meta‐analysis of the effect of thiazolidinediones on blood pressure
- Effects of thiazolidinediones and sulfonylureas in patients with diabetes
- Thiazolidinediones, like metformin, inhibit respiratory complex I: a common mechanism contributing to their antidiabetic actions?
- Thiazolidinediones and metformin associated with improved survival of diabetic prostate cancer patients
- Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro
- Therapeutic potential of thiazolidinediones as anticancer agents
- Thiazolidinediones and fatty acids convert myogenic cells into adipose-like cells
- Comparative effects of thiazolidinediones on in vitro P450 enzyme induction and inhibition
- Thiazolidinediones repress ob gene expression in rodents via activation of peroxisome proliferator-activated receptor gamma.
- Redefining the role of thiazolidinediones in the management of type 2 diabetes
- The effect of thiazolidinediones on adiponectin serum level: a meta‐analysis
- The Structure− Activity relationship between peroxisome proliferator-activated receptor γ agonism and the antihyperglycemic activity of thiazolidinediones
- Effective use of thiazolidinediones for the treatment of glucocorticoid-induced diabetes
- Brain PPAR-γ promotes obesity and is required for the insulin–sensitizing effect of thiazolidinediones
- Thiazolidinediones and type 2 diabetes: new drugs for an old disease
- Thiazolidinediones and cardiovascular risk—a question of balance
- Reassessing the cardiovascular risks and benefits of thiazolidinediones
- Comparison of effects of thiazolidinediones on cardiovascular risk factors: observations from a clinical practice
- Thiazolidinediones regulate adipose lineage dynamics
- Association between cancer prevalence and use of thiazolidinediones: results from the Vermont Diabetes Information System
- Thiazolidinediones ameliorate diabetic nephropathy via cell cycle–dependent mechanisms
- Thiazolidinediones and fracture risk in patients with type 2 diabetes
- Clinical efficacy of new thiazolidinediones and glinides in the treatment of type 2 diabetes mellitus
- Effect of thiazolidinediones on glucose and fatty acid metabolism in patients with type 2 diabetes
- A cohort study of thiazolidinediones and fractures in older adults with diabetes
- Thiazolidinediones expand body fluid volume through PPARγ stimulation of ENaC-mediated renal salt absorption
- Thiazolidinediones and antiblastics in primary human anaplastic thyroid cancer cells
- The risk of fractures associated with thiazolidinediones: a self-controlled case-series study
- Peroxisome proliferator-activated receptor-gamma activation by thiazolidinediones induces adipogenesis in bone marrow stromal cells.
- Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
- Thiazolidinediones, peripheral oedema and congestive heart failure: what is the evidence?
- Evaluation of metabolite profiles as biomarkers for the pharmacological effects of thiazolidinediones in Type 2 diabetes mellitus patients and healthy volunteers
- Thiazolidinediones in diabetes: current status and future outlook.
- Recent thiazolidinediones as antidiabetics
- Effects of metformin and thiazolidinediones on suppression of hepatic glucose production and stimulation of glucose uptake in type 2 diabetes: a systematic …
- Mechanisms by which thiazolidinediones induce anti-cancer effects in cancers in digestive organs
- The effects of thiazolidinediones on blood pressure levels–a systematic review
- Effects of thiazolidinediones on stroke recovery: a case-matched controlled study
- Effects of thiazolidinediones beyond glycaemic control
- The controversial effects of thiazolidinediones on cardiovascular morbidity and mortality
- Diabetic KKAy mice exhibit increased hepatic PPARγ1 gene expression and develop hepatic steatosis upon chronic treatment with antidiabetic thiazolidinediones
- Down regulation of peroxisome proliferator-activated receptorγ expression by inflammatory cytokines and its reversal by thiazolidinediones
- Anticancer effects of thiazolidinediones are independent of peroxisome proliferator-activated receptor γ and mediated by inhibition of translation initiation
- Regulation of triglyceride metabolism by PPARs: fibrates and thiazolidinediones have distinct effects
- Thiazolidinediones reduce endothelial expression of receptors for advanced glycation end products
- Effectiveness and long-term safety of thiazolidinediones and metformin in renal transplant recipients
- Thiazolidinediones increase plasma-adipose tissue FFA exchange capacity and enhance insulin-mediated control of systemic FFA availability
- Trans-differentiation of myoblasts to adipoblasts: triggering effects of fatty acids and thiazolidinediones
- Mechanisms of action of thiazolidinediones
- Elevated plasma levels of the atherogenic mediator soluble CD40 ligand in diabetic patients: a novel target of thiazolidinediones
- Action of thiazolidinediones on differentiation, proliferation and apoptosis of normal and transformed thyrocytes in culture
- Thiazolidinediones and glucocorticoids synergistically induce differentiation of human adipose tissue stromal cells: biochemical, cellular, and molecular analysis
- Association between use of thiazolidinediones or other oral antidiabetics and psoriasis: A population based case-control study
- The role of metformin and thiazolidinediones in the regulation of hepatic glucose metabolism and its clinical impact
- Thiazolidinediones in dermatology
- Thiazolidinediones and insulin resistance: Peroxisome proliferatoractivated receptor γ activation stimulates expression of the CAP gene
- Synthesis and biological activity of novel acridinylidene and benzylidene thiazolidinediones
- Structure–activity relationships and molecular modelling of 5-arylidene-2, 4-thiazolidinediones active as aldose reductase inhibitors
- Synthesis and biological activity of novel thiazolidinediones
- Energy restriction as an antitumor target of thiazolidinediones
- Discovery of 5-aryloxy-2, 4-thiazolidinediones as potent GPR40 agonists
- Cardiovascular risk and thiazolidinediones—what do meta‐analyses really tell us?
- Thiazolidinediones produce a conformational change in peroxisomal proliferator-activated receptor-gamma: binding and activation correlate with antidiabetic actions …
- Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents
- Novel phthalazinone and benzoxazinone containing thiazolidinediones as antidiabetic and hypolipidemic agents
- Thiazolidinediones and risk of heart failure in patients with or at high risk of type 2 diabetes mellitus: a meta-analysis and meta-regression analysis of placebo …
- The preventive anti‐oxidant action of thiazolidinediones: a new therapeutic prospect in diabetes and insulin resistance
- β-cell preservation with thiazolidinediones
- Effects of thiazolidinediones on blood pressure
- Thiazolidinediones for initial treatment of type 2 diabetes?
- Response of experimental retinal neovascularization to thiazolidinediones
- Mitochondrial permeability transition as a potential determinant of hepatotoxicity of antidiabetic thiazolidinediones
- Thiazolidinediones for treatment of polycystic ovary syndrome
- Beyond peroxisome proliferator-activated receptor γ signaling: the multi-facets of the antitumor effect of thiazolidinediones
- Thiazolidinediones: a review of their mechanisms of insulin sensitization, therapeutic potential, clinical efficacy, and tolerability
- Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients
- Thiazolidinediones and their fluid-related adverse effects: facts, fiction and putative management strategies
- Rationale for and role of thiazolidinediones in type 2 diabetes mellitus
- Mechanism of the anti-inflammatory effect of thiazolidinediones: relationship with the glucocorticoid pathway
- Progress with thiazolidinediones in the management of type 2 diabetes mellitus
- Thiazolidinediones but not metformin directly inhibit the steroidogenic enzymes P450c17 and 3β-hydroxysteroid dehydrogenase
- Thiazolidinediones as therapy for endometriosis: a case series
- Development of insulin resistance and reversal by thiazolidinediones in C2C12 skeletal muscle cells
- A novel mechanism by which thiazolidinediones facilitate the proteasomal degradation of cyclin D1 in cancer cells
- Thiazolidinediones on PPARγ: The Roles in Bone Remodeling
- Thiazolidinediones and fertility in polycystic ovary syndrome (PCOS)
- A review of thiazolidinediones and metformin in the treatment of type 2 diabetes with focus on cardiovascular complications
- Thiazolidinediones in the treatment of type 2 diabetes
- A new concept underlying stem cell lineage skewing that explains the detrimental effects of thiazolidinediones on bone
- The role of thiazolidinediones in the treatment of patients with type 2 diabetes mellitus
- Synthesis, characterization and antimicrobial activity evaluation of new 2, 4-Thiazolidinediones bearing imidazo [2, 1-b][1, 3, 4] thiadiazole moiety
- A comparison of the effects of thiazolidinediones and metformin on metabolic control in patients with type 2 diabetes mellitus
- Regulation of lipoprotein metabolism by thiazolidinediones occurs through a distinct but complementary mechanism relative to fibrates
- Metformin vs thiazolidinediones for treatment of clinical, hormonal and metabolic characteristics of polycystic ovary syndrome: a meta‐analysis
- Management of co-existing diabetes mellitus and dyslipidemia: defining the role of thiazolidinediones
- Thiazolidinediones and clinical outcomes in type 2 diabetes
- Long-term use of thiazolidinediones and the associated risk of pneumonia or lower respiratory tract infection: systematic review and meta-analysis
- β-Cell rejuvenation with thiazolidinediones
- Drug insight: thiazolidinediones and diabetic nephropathy—relevance to renoprotection
- the treatment of non‐alcoholic steatohepatitis with thiazolidinediones
- Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms
- Addressing the insulin resistance syndrome: a role for the thiazolidinediones
- Peroxisome proliferator-activated receptor γ-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells
- Dual PPAR-α and-γ activators derived from novel benzoxazinone containing thiazolidinediones having antidiabetic and hypolipidemic potential
- Thiazolidinediones in type 2 diabetes: a cardiology perspective
- The potential of antidiabetic thiazolidinediones for anticancer therapy
- Cytotoxic effect of different statins and thiazolidinediones on malignant glioma cells
- Thiazolidinediones (PPARγ agonists) but not PPAR α agonists increase IRS‐2 gene expression in 3T3‐L1 and human adipocytes1
- Thiazolidinediones suppress endothelin-1 secretion from bovine vascular endothelial cells: a new possible role of PPARγ on vascular endothelial function
- Central role of the adipocyte in the insulin-sensitising and cardiovascular risk modifying actions of the thiazolidinediones
- Thiazolidinediones down-regulate plasminogen activator inhibitor type 1 expression in human vascular endothelial cells: a possible role for PPARγ in endothelial …
- The cardiovascular effects of the thiazolidinediones: a review of the clinical data
- Differential regulation of the stearoyl-CoA desaturase genes by thiazolidinediones in 3T3-L1 adipocytes
- Adiponectin gene activation by thiazolidinediones requires PPARγ2, but not C/EBPα—evidence for differential regulation of the aP2 and adiponectin genes
- Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment
- Thiazolidinediones: pleiotropic drugs with potent anti-inflammatory properties for tissue protection
- Thiazolidinediones are partial agonists for the glucocorticoid receptor
- Thiazolidinediones for nonalcoholic steatohepatitis—promising but not ready for prime time
- Pleiotropic effects of thiazolidinediones on traditional and non‐traditional atherosclerotic risk factors
- Thiazolidinediones Inhibit Osteoclast-Like Cell Formation and Bone Resorption in Vitro
- Role of PPAR-γ agonist thiazolidinediones in treatment of pre-diabetic and diabetic individuals: a cardiovascular perspective
- Section review: oncologic, endocrine & metabolic: thiazolidinediones
- Effects of the thiazolidinediones on cardiovascular risk factors
- Thiazolidinediones: do harms outweigh benefits?
- Thiazolidinediones: a review of their benefits and risks
- Anti-inflammatory effect of antidiabetic thiazolidinediones prevents bone resorption rather than cartilage changes in experimental polyarthritis
- Thiazolidinediones induce osteocyte apoptosis and increase sclerostin expression
- Thiazolidinediones inhibit growth and invasiveness of the human adrenocortical cancer cell line H295R
- Anti-inflammatory effects of thiazolidinediones in human airway smooth muscle cells
- [[. omega.-(Heterocyclylamino) alkoxy] benzyl]-2, 4-thiazolidinediones as potent antihyperglycemic agents
- Thiazolidinediones reduce pathological neovascularization in ischemic retina via an adiponectin-dependent mechanism
- Thiazolidinediones, peroxisome proliferator-activated receptor γ agonists, regulate endothelial cell growth and secretion of vasoactive peptides
- Synthesis, biological evaluation and molecular modeling studies of arylidene-thiazolidinediones with potential hypoglycemic and hypolipidemic activities
- The new clinical trials with thiazolidinediones–DREAM, ADOPT, and CHICAGO: promises fulfilled?
- Topical treatment with thiazolidinediones, activators of peroxisome proliferator‐activated receptor‐γ, normalizes epidermal homeostasis in a murine hyperproliferative …
- Impaired adipogenic response to thiazolidinediones in mice expressing human apolipoproteinE4
- Thiazolidinediones: beyond glycemic control
- Thiazolidinediones provide better renoprotection than insulin in an obese, hypertensive type II diabetic rat model
- Antidiabetic thiazolidinediones block the inhibitory effect of tumor necrosis factor-alpha on differentiation, insulin-stimulated glucose uptake, and gene expression in …
- Do thiazolidinediones cause heart failure? A critical review.
- Thiazolidinediones: novel treatments for cognitive deficits in mood disorders?
- Thiazolidinediones: a pharmacological overview
- Thiazolidinediones inhibit TNFα induction of PAI-1 independent of PPARγ activation
- Thiazolidinediones inhibit the expression of beta3-adrenergic receptors at a transcriptional level.
- Cardiovascular effects of the thiazolidinediones
- β‐cell preservation: a potential role for thiazolidinediones to improve clinical care in Type 2 diabetes
- Factors associated with results and conclusions of trials of thiazolidinediones
- Vascular reactivity and thiazolidinediones
- Thiazolidinediones and rexinoids induce peroxisome proliferator-activated receptor-coactivator (PGC)-1α gene transcription: an autoregulatory loop controls PGC-1α …
- The molecular mechanisms underlying the proinflammatory actions of thiazolidinediones in human macrophages
- PPARγ activation by thiazolidinediones (TZDs) may modulate breast carcinoma outcome: the importance of interplay with TGFβ signalling
- Administration of thiazolidinediones for neuroprotection in ischemic stroke: a pre‐clinical systematic review
- Biguanides and thiazolidinediones inhibit stimulated lipolysis in human adipocytes through activation of AMP-activated protein kinase
- Differential modulation of farnesoid X receptor signaling pathway by the thiazolidinediones
- The potential role of thiazolidinediones in atrial fibrillation
- A placebo‐controlled trial of exenatide twice‐daily added to thiazolidinediones alone or in combination with metformin
- Evaluation of the sensitivity to chemotherapeutics or thiazolidinediones of primary anaplastic thyroid cancer cells obtained by fine-needle aspiration
- Antiatherogenic effects of thiazolidinediones?
- Lack of association between thiazolidinediones and macular edema in type 2 diabetes: the ACCORD eye substudy
- Thiazolidinediones in patients with type 2 diabetes mellitus and heart failure
- Fluid retention with thiazolidinediones: does the mechanism influence the outcome?
- Role of PPAR in the pharmacological regulation of lipoprotein metabolism by fibrates and thiazolidinediones
- Severe cholestatic hepatitis caused by thiazolidinediones: risks associated with substituting rosiglitazone for troglitazone
- Thiazolidinediones upregulate impaired fatty acid uptake in skeletal muscle of type 2 diabetic subjects
- Pro-inflammatory properties for thiazolidinediones
- Thiazolidinediones and type 2 diabetes: from cellular targets to cardiovascular benefit
- Thiazolidinediones increase the wingless-type MMTV integration site family (WNT) inhibitor Dickkopf-1 in adipocytes: a link with osteogenesis
- Combination therapy using metformin or thiazolidinediones and insulin in the treatment of diabetes mellitus
- Thiazolidinediones: new evidence of bone loss
- Fracture risk a class effect of thiazolidinediones in women
- Pleiotropic actions of PPARg activators thiazolidinediones in cardiovascular diseases
- Thiazolidinediones: a novel class of drugs for the prevention of diabetic nephropathy?
- Acute and selective regulation of glyceroneogenesis and cytosolic phosphoenolpyruvate carboxykinase in adipose tissue by thiazolidinediones in type 2 …
- Thiazolidinediones (AD-4833 and CS-045) improve hepatic insulin resistance in streptozotocin-induced diabetic rats
- The effects of fibrates and thiazolidinediones on plasma triglyceride metabolism are mediated by distinct peroxisome proliferator activated receptors (PPARs)
- Thiazolidinediones stimulate uncoupling protein-2 expression in cell lines representing white and brown adipose tissues and skeletal muscle
- Thiazolidinediones downregulate stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes
- Thiazolidinediones induce proliferation of human bronchial epithelial cells through the GPR40 receptor
- Meta-analysis of the effect of thiazolidinediones on serum C-reactive protein levels
- Thiazolidinediones and risk of repeat target vessel revascularization following percutaneous coronary intervention: a meta-analysis
- Cardiovascular risk and the thiazolidinediones: déjà vu all over again?
- Thiazolidinediones and risk for atherosclerosis: pleiotropic effects of PPARγ agonism
- Comparison of the antidiabetic effects of brain‐derived neurotrophic factor and thiazolidinediones in obese diabetic mice
- Thiazolidinediones and cardiovascular events in patients with type 2 diabetes mellitus: a retrospective cohort study of over 473 000 patients using the National Health …
- Thiazolidinediones—benefits on microvascular complications of type 2 diabetes
- Effect of thiazolidinediones on skeletal health in women with Type 2 diabetes
- Thiazolidinediones enhance sodium-coupled bicarbonate absorption from renal proximal tubules via PPARγ-dependent nongenomic signaling
- Specific thiazolidinediones inhibit ovarian cancer cell line proliferation and cause cell cycle arrest in a PPARγ independent manner
- Insulin sensitizing pharmacology of thiazolidinediones correlates with mitochondrial gene expression rather than activation of PPARγ
- Negative regulation of the oncogenic transcription factor FoxM1 by thiazolidinediones and mithramycin
- Effect of thiazolidinediones and metformin on LDL oxidation and aortic endothelium relaxation in diabetic GK rats
- Comparison of direct action of thiazolidinediones and glucocorticoids on renal podocytes: protection from injury and molecular effects
- Thiazolidinediones decrease vascular endothelial growth factor (VEGF) production by human luteinized granulosa cells in vitro
- Thiazolidinediones: effects on the development and progression of type 2 diabetes and associated vascular complications
- Thiazolidinediones-the new insulin enhancers
- Insulin resistance and the effects of thiazolidinediones on cardiac metabolism
- Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer
- Thiazolidinediones and the risk of incident congestive heart failure among patients with type 2 diabetes mellitus
- Thiazolidinediones plus metformin association on body weight in patients with type 2 diabetes
- Thiazolidinediones: clinical data and perspectives
- Thiazolidinediones and their effects on glucose transporters
- Thiazolidinediones as a novel class of algicides against red tide harmful algal species
- The thiazolidinediones rosiglitazone and pioglitazone and the risk of coronary heart disease: a retrospective cohort study using a US health insurance database
- Thiazolidinediones for the prevention of diabetes in the non‐obese diabetic (NOD) mouse: implications for human type 1 diabetes
- Thiazolidinediones and bone
- Hypoglycemic Action of Thiazolidinediones/Peroxisome Proliferator–Activated Receptor γ by Inhibition of the c-Jun NH2-Terminal Kinase Pathway
- Thiazolidinediones improve insulin sensitivity in adipose tissue and reduce the hyperlipidaemia without affecting the hyperglycaemia in a transgenic model of …
- A “futile cycle” induced by thiazolidinediones in human adipose tissue?
- Where thiazolidinediones will fit
- Differential effect of the antidiabetic thiazolidinediones troglitazone and pioglitazone on human platelet aggregation mechanism.
- The influence of thiazolidinediones on adipogenesis in vitro and in vivo: Potential modifiers of intramuscular adipose tissue deposition in meat animals,
- Thiazolidinediones inhibit hepatocarcinogenesis in hepatitis B virus–transgenic mice by peroxisome proliferator‐activated receptor γ–independent regulation of …
- Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the general practice research database and secondary care data
- Leukopenia and thrombocytopenia caused by thiazolidinediones
- The roles of insulin resistance, hyperinsulinemia, and thiazolidinediones in cardiovascular disease
- Lipoprotein effects of different thiazolidinediones in clinical practice
- Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes
- Investigation of the lipophilic behaviour of some thiazolidinediones: Relationships with PPAR-γ activity
- Thiazolidinediones regulate expression of cell cycle proteins in human prostate cancer cells via PPARγ-dependent and PPARγ-independent pathways
- Rapid racemization in thiazolidinediones: a quantum chemical study
- Thiazolidinediones inhibit insulin-like growth factor-I–induced activation of p70S6 kinase and suppress insulin-like growth factor-I tumor-promoting activity
- Effect of thiazolidinediones on bile acid transport in rat liver
- Novel actions of thiazolidinediones on vascular function and exercise capacity
- Thiazolidinediones enhance skeletal muscle triacylglycerol synthesis while protecting against fatty acid-induced inflammation and insulin resistance
- Evaluation of proinflammatory cytokines and inflammation markers as biomarkers for the action of thiazolidinediones in Type 2 diabetes mellitus patients and healthy …
- Synthesis of 5-arylidene-2, 4-thiazolidinediones by Knoevenagel condensation catalyzed by baker’s yeast
- 3T3‐L1 adipocyte apoptosis induced by thiazolidinediones is peroxisome proliferator‐activated receptor‐γ‐dependent and mediated by the caspase‐3‐dependent …
- Substituted thiazolidinediones and thio-imidazolidinones: synthesis, structural study and pharmacological activity.
- Extension of the neuroprotective time window for thiazolidinediones in ischemic stroke is dependent on time of reperfusion
- Synthesis of new pyrazolyl-2, 4-thiazolidinediones as antibacterial and antifungal agents
- Is weight loss possible in patients treated with thiazolidinediones? Experience with a low-calorie diet
- Peroxisome proliferator-activated receptor γ-independent activation of p38 MAPK by thiazolidinediones involves calcium/calmodulin-dependent protein …
- Insulin-sensitizing agents–thiazolidinediones (glitazones)
- Effects of retinoids and thiazolidinediones on proliferation, insulin release, insulin mRNA, GLUT 2 transporter protein and mRNA of INS‐1 cells
- Effects of sulfonylureas on peroxisome proliferator-activated receptor γ activity and on glucose uptake by thiazolidinediones
- Metformin, but not thiazolidinediones, inhibits plasminogen activator inhibitor-1 production in human adipose tissue in vitro
- Synthetic thiazolidinediones: potential antidiabetic compounds
- Mechanism for antioxidative effects of thiazolidinediones in pancreatic β-cells
- Thiazolidinediones inhibit lipoprotein lipase activity in adipocytes
- Approach to the management of diabetic patients with heart failure: role of thiazolidinediones
- Thiazolidinediones for the treatment in NASH: sustained benefit after drug discontinuation?
- Thiazolidinediones mimic glucose starvation in facilitating Sp1 degradation through the up-regulation of β-transducin repeat-containing protein
- Effects of thiazolidinediones on growth and differentiation of human aorta and coronary myocytes
- Risk of cardiovascular events and all-cause mortality in patients treated with thiazolidinediones in a managed-care population
- Monogenic polycystic ovary syndrome due to a mutation in the lamin A/C gene is sensitive to thiazolidinediones but not to metformin
- Thiazolidinediones: comparison of long-term effects on glycemic control and cardiovascular risk factors
- Thiazolidinediones downregulate Wnt/β-catenin signaling via multiple mechanisms in breast cancer cells
- Chronic and acute effects of thiazolidinediones BM13. 1258 and BM15. 2054 on rat skeletal muscle glucose metabolism
- Thiazolidinediones and hepatic fibrosis: don’t wait too long
- The effects of thiazolidinediones on vascular smooth muscle cell activation by angiotensin II
- Thiazolidinediones in type 2 diabetes. Role of peroxisome proliferator-activated receptor gamma (PPARgamma)
- Thiazolidinediones, dyslipidaemia and insulin resistance syndrome
- A selective peroxisome proliferator-activated receptor-γ modulator, telmisartan, binds to the receptor in a different fashion from thiazolidinediones
- PEROXISOME PROLIFERATOR‐ACTIVATED RECEPTOR γ‐INDEPENDENT EFFECTS OF THIAZOLIDINEDIONES ON HUMAN CARDIAC MYOFIBROBLAST …
- Effect of thiazolidinediones on expression of UCP2 and adipocyte markers in human PAZ6 adipocytes
- Therapeutic potential of thiazolidinediones in activation of peroxisome proliferator-activated receptor γ for monocyte recruitment and endothelial regeneration
- Thiazolidinediones for NASH—one pill doesn’t fix everything
- Thiazolidinediones as a novel class of NAD+-dependent 15-hydroxyprostaglandin dehydrogenase inhibitors
- Cost‐Effectiveness Analysis of Thiazolidinediones in Uncontrolled Type 2 Diabetic Patients Receiving Sulfonylureas and Metformin in Thailand
- The effects of thiazolidinediones on metabolic complications and lipodystrophy in HIV-infected patients
- Thiazolidinediones and bone fractures
- Thiazolidinediones are novel insulin-sensitizing agents
- Peroxisome proliferator-activated receptor γ-independent repression of prostate-specific antigen expression by thiazolidinediones in prostate cancer cells
- Regulation of glyceroneogenesis and phosphoenolpyruvate carboxykinase by fatty acids, retinoic acids and thiazolidinediones: potential relevance to type 2 diabetes
- Thiazolidinediones in patients with diabetes mellitus and heart failure: implications of emerging data
- Antagonistic effects of thiazolidinediones and cytokines in lipotoxicity
- Thiazolidinediones: potential as therapeutics for psoriasis and perhaps other hyperproliferative skin disease
- Insulin resistance, diabetes, and atherosclerosis: thiazolidinediones as therapeutic interventions
- Thiazolidinediones inhibit apoptosis and heat shock protein 60 expression in human vascular endothelial cells
- Effect of thiazolidinediones on in-stent restenosis in patients after coronary stenting: a meta-analysis of randomized controlled trials
- Thiazolidinediones—improving endothelial function and potential long-term benefits on cardiovascular disease in subjects with type 2 diabetes
- Cellular and molecular effects of thiazolidinediones on bone cells: a review
- Differential effects of peroxisome proliferator activated receptor-γ (PPARγ) ligands in proximal tubular cells: Thiazolidinediones are partial PPARγ agonists
- Beneficial effects of thiazolidinediones on diabetic nephropathy in OLETF rats
- Synthesis and biological evaluation of novel pyrazolyl-2, 4-thiazolidinediones as anti-inflammatory and neuroprotective agents
- Thiazolidinediones are potent inducers of fibroblast growth factor 21 expression in the liver
- Antidiabetic thiazolidinediones induce ductal differentiation but not apoptosis in pancreatic cancer cells
- Thiazolidinediones, deadly sins, surrogates, and elephants
- Interaction of thiazolidinediones (glitazones) with the ATP-binding cassette transporters P-glycoprotein and breast cancer resistance protein
- Effect of thiazolidinediones on high-density lipoprotein subfractions
- The anti-atherogenic effects of thiazolidinediones
- Stimulation of resorption in cultured mouse calvarial bones by thiazolidinediones
- Clinical use of thiazolidinediones: recommendations
- Effects of thiazolidinediones on glucocorticoid-induced insulin resistance and GLUT4 glucose transporter expression in rat skeletal muscle
- Do thiazolidinediones cause congestive heart failure?
- Congestive heart failure and cardiovascular death in patients with prediabetes and type 2 diabetes given thiazolidinediones: a meta-analysis of randomised clinical …
- Thiazolidinediones enhance vascular endothelial growth factor expression and induce cell growth inhibition in non-small-cell lung cancer cells
- Insulin-sensitizing effects of thiazolidinediones are not linked to adiponectin receptor expression in human fat or muscle
- Thiazolidinediones: a new class of drugs for the therapy of ischemia-reperfusion injury.
- Clinical trials with thiazolidinediones in subjects with Type 2 diabetes–is pioglitazone any different from rosiglitazone?
- Thiazolidinediones inhibit proliferation of microvascular and macrovascular cells by a PPARγ-independent mechanism
- Nonhypoglycemic effects of thiazolidinediones
- Thiazolidinediones and fluid retention
- An overview of the beneficial cardiovascular effects of thiazolidinediones
- Synthesis of peptides in aqueous medium. VII. Preparation and use of 2, 5-thiazolidinediones in peptide synthesis
- The association between thiazolidinediones and hospitalisation for fracture in type 2 diabetic patients: a Taiwanese population-based nested case–control …
- Thiazolidinediones in prediabetes and early type 2 diabetes: what can be learned about that disease’s pathogenesis
- Alteration in expression profiles of a series of diabetes-related genes in db/db mice following treatment with thiazolidinediones
- The emerging role of thiazolidinediones in the treatment of diabetes-mellitus and related disorders
- Differential effects among thiazolidinediones on the transcription of thromboxane receptor and angiotensin II type 1 receptor genes
- Novel benzoxazole 2, 4-thiazolidinediones as potent hypoglycemic agents. Synthesis and structure-activity relationships
- Cytotoxic effects of statins and thiazolidinediones on meningioma cells
- 2, 4-Thiazolidinediones as potent and selective human β3 agonists
- The effect of thiazolidinediones on bone mineral density in Chinese older patients with type 2 diabetes
- Risk of acute myocardial infarction in patients treated with thiazolidinediones or other antidiabetic medications
- … of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: update regarding thiazolidinediones: a consensus statement …
- Synthesis and aldose reductase inhibitory activity of 5-arylidene-2, 4-thiazolidinediones
- Thiazolidinediones and vascular damage
- Thiazolidinediones and the preservation of β‐cell function, cellular proliferation and apoptosis
- Can thiazolidinediones delay disease progression in type 2 diabetes?
- Use of thiazolidinediones in HIV-infected patients: what have we learned?
- Insulin-sensitising agents: beyond thiazolidinediones
- Mechanism of action of thiazolidinediones.
- Different effects of thiazolidinediones on cardiovascular risk in patients with type 2 diabetes mellitus: pioglitazone vs rosiglitazone
- Thiazolidinediones Induce Rab7–RILP–MAPK‐Dependent Juxtanuclear Lysosome Aggregation and Reduce Tumor Cell Invasion
- Inhibition of TGF-β expression: a novel role for thiazolidinediones to implement renoprotection in diabetes
- Thiazolidinediones and the risk of incident strokes in patients with type 2 diabetes: a nested case‐control study
- Three-dimensional quantitative structure-activity relationships (3D-QSAR) of antidiabetic thiazolidinediones.
- Adverse events with concomitant use of simvastatin or atorvastatin and thiazolidinediones
- The role of the thiazolidinediones in the practical management of patients with type 2 diabetes and cardiovascular risk factors.
- Long‐term glycaemic efficacy and weight changes associated with thiazolidinediones when added at an advanced stage of type 2 diabetes
- Thiazolidinediones inhibit REG Iα gene transcription in gastrointestinal cancer cells
- Tissue-specific actions of antidiabetic thiazolidinediones on the reduced fatty acid oxidation in skeletal muscle and liver of Zucker diabetic fatty rats
- Thiazolidinediones may contribute to the intramyocardial lipid accumulation in diabetic myocardium: effects on cardiac function
- Quantitative structure–activity analysis of 5-arylidene-2, 4-thiazolidinediones as aldose reductase inhibitors
- Thiazolidinediones for the therapeutic management of polycystic ovary syndrome: impact on metabolic and reproductive abnormalities
- Treating insulin resistance in type 2 diabetes with metformin and thiazolidinediones
- C‐reactive protein, its role in inflammation, type 2 diabetes and cardiovascular disease, and the effects of insulin‐sensitizing treatment with thiazolidinediones
- Thiazolidinediones inhibit growth of gastrointestinal, biliary, and pancreatic adenocarcinoma cells through activation of the peroxisome proliferator-activated receptor γ …
- Thiazolidinediones and cardiovascular events in high-risk patients with type-2 diabetes mellitus: a comparison with other oral antidiabetic agents
- Thiazolidinediones and insulin: rationale for use and role of combination therapy in type 2 diabetes mellitus
- Thiazolidinediones modulate the expression of β-catenin and other cell-cycle regulatory proteins by targeting the F-box proteins of Skp1-Cul1-F-box protein E3 …
- Differential effects of thiazolidinediones on adipocyte growth and recruitment in Zucker fatty rats
- Insights on distinct pathways of thiazolidinediones (PPARγ ligand)‐promoted apoptosis in TRAIL‐sensitive or‐resistant malignant urothelial cells
- Studies on antidiabetic agents. Synthesis and hypoglycemic activity of 5-[4-(pyridylalkoxy) benzyl]-2, 4-thiazolidinediones.
- Effects of thiazolidinediones for early treatment of type 2 diabetes mellitus
- … review and meta‐analysis of controlled trials using carotid intima‐media thickness or pulse wave velocity to infer antiatherogenic properties of thiazolidinediones
- Expression and characterization of recombinant rat acyl-CoA synthetases 1, 4, and 5: selective inhibition by triacsin C and thiazolidinediones
- The thiazolidinediones or” glitazones” a treatment option for type 2 diabetes mellitus.
- Could thiazolidinediones increase the risk of heart failure in Friedreich’s ataxia patients?
- Mechanism of TNFα-induced IL-1α, IL-1β and IL-6 expression in human cardiac fibroblasts: effects of statins and thiazolidinediones
- Thiazolidinediones increase hepatic insulin extraction in African Americans with impaired glucose tolerance and type 2 diabetes mellitus. A pilot study of rosiglitazone
- Thiazolidinediones enhance insulin-mediated suppression of fatty acid flux in type 2 diabetes mellitus
- Furan-2-ylmethylene thiazolidinediones as novel, potent, and selective inhibitors of phosphoinositide 3-kinase γ
- Thiazolidinediones up-regulate insulin-like growth factor-1 receptor via a peroxisome proliferator-activated receptor γ-independent pathway
- … of hyperglycaemia in type 2 diabetes mellitus: a consensus algorithm for the initiation and adjustment of therapy: Update regarding the thiazolidinediones
- Effects of combination of thiazolidinediones with melatonin in dexamethasone-induced insulin resistance in mice
- Targeting insulin resistance and β-cell dysfunction: the role of thiazolidinediones
- 15-PGJ2, but not thiazolidinediones, inhibits cell growth, induces apoptosis, and causes downregulation of Stat3 in human oral SCCa cells
- Synthesis and biological activity of [[(heterocycloamino) alkoxy] benzyl]-2, 4-thiazolidinediones as PPARγ agonists
- Thiazolidinediones inhibit alkaline phosphatase activity while increasing expression of uncoupling protein, deiodinase, and increasing mitochondrial mass in …
- Thiazolidinediones and congestive heart failure—exacerbation or new onset of left ventricular dysfunction?
- Role of Thiazolidinediones in the Management of Type 2 Diabetes
- Thiazolidinediones (PPARγ ligands) increase IRS-1, UCP-2 and C/EBPα expression, but not transdifferentiation, in L6 muscle cells
- Using thiazolidinediones: rosiglitazone and pioglitazone in clinical practice
- Thiazolidinediones inhibit cell growth of human oral squamous cell carcinoma in vitro independent of peroxisome proliferator-activated receptor γ
- Thiazolidinediones: potential link between insulin resistance and cardiovascular disease
- Thiazolidinediones and congestive heart failure: a judicious balance of risks and benefits
- Thiazolidinediones inhibit TNF-α-mediated osteoclast differentiation of RAW264. 7 macrophages and mouse bone marrow cells through downregulation of NFATC1
- Insulin resistance, adipocyte biology, and thiazolidinediones: a review
- BRL 49653 blocks the lipolytic actions of tumor necrosis factor-alpha: a potential new insulin-sensitizing mechanism for thiazolidinediones.
- Short insulin tolerance test can determine the effects of thiazolidinediones treatment in type 2 diabetes
- Effect of thiazolidinediones on equilibrative nucleoside transporter-1 in human aortic smooth muscle cells
- Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study: response to Delea et al.
- The use of optical coherence tomography to determine the effect of thiazolidinediones on retinal thickness in patients with type 2 diabetes
- Thiazolidinediones and congestive heart failure in veterans with type 2 diabetes
- Thiazolidinediones influence plasma steroids of male obese Zucker rats
- Skeletal toxicity of thiazolidinediones
- Thiazolidinediones, cardiovascular disease and cardiovascular mortality: translating research into action for diabetes (TRIAD)
- Cinnamic acid based thiazolidinediones inhibit human P450c17 and 3beta-hydroxysteroid dehydrogenase and improve insulin sensitivity independent of …
- Adiponectin receptor gene expression in human skeletal muscle cells is not regulated by fibrates and thiazolidinediones
- Comparison of metformin and thiazolidinediones in the management of polycystic ovary syndrome
- Pyruvate dehydrogenase kinase 4: regulation by thiazolidinediones and implication in glyceroneogenesis in adipose tissue
- Commentary: What can we learn from the continuing regulatory focus on the thiazolidinediones?
- Thiazolidinediones and progression of renal disease in patients with diabetes
- Thiazolidinediones with thyroid hormone receptor agonistic activity
- Thiazolidinediones and cardiovascular outcomes in type 2 diabetes
- Capacitative calcium entry contributes to the differential transactivation of the epidermal growth factor receptor in response to thiazolidinediones
- NASH and thiazolidinediones: not to be taken lightly
- Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones
- Thiazolidinediones and diabetic nephropathy: need for a closer examination?
- 5-Arylidene-2, 4-thiazolidinediones as inhibitors of protein tyrosine phosphatases
- Effect of thiazolidinediones on the erythropoeitic and germinal cells in the male wistar rats
- Thiazolidinediones inhibit the progression of established hypertension in the Dahl salt-sensitive rat
- In vitro aldose reductase inhibitory activity of 5-benzyl-2, 4-thiazolidinediones
- Effect of thiazolidinediones on lipid profile
- Cardiovascular disease and benefits of thiazolidinediones.
- The impacts of thiazolidinediones on circulating C-reactive protein levels in different diseases: a meta-analysis
- Thiazolidinediones reduce the LDL binding affinity of non-human primate vascular cell proteoglycans
- 15-Deoxy-Δ12, 14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle …
- Adiponectin-dependent and-independent pathways in insulin-sensitizing and antidiabetic actions of thiazolidinediones
- Thiazolidinediones increase arachidonic acid release and subsequent prostanoid production in a peroxisome proliferator-activated receptor γ-independent manner
- Thiazolidinediones and the influence of media adverse reporting on prescribing attitudes in practice (TZD‐IMPACT) study
- Anti-proliferative activity of oral anti-hyperglycemic agents on human vascular smooth muscle cells: thiazolidinediones (glitazones) have enhanced activity …
- Pharmacological therapy for non‐alcoholic steatohepatitis: How efficient are thiazolidinediones?
- Thiazolidinediones: antidiabetic drugs with cardiovascular effects
- Solution-and solid-phase synthesis of peptide-substituted thiazolidinediones as potential PPAR ligands
- Why might thiazolidinediones increase exercise capacity in patients with type 2 diabetes?
- Thiazolidinediones inhibit MDCK cyst growth through disrupting oriented cell division and apicobasal polarity
- Electrophilic α-thiocyanation of chiral and achiral N-acyl imides. A convenient route to 5-substituted and 5, 5-disubstituted 2, 4-thiazolidinediones
- The metabolic syndrome: evolving evidence that thiazolidinediones provide rational therapy
- Point: recent long-term clinical studies support an enhanced role for thiazolidinediones in the management of type 2 diabetes
- Thiazolidinediones inhibit the growth of PC12 cells both in vitro and in vivo
- A meta-analysis on treatment effects of thiazolidinediones for type 2 diabetes mellitus in Asian populations
- Thiazolidinediones prevent PDGF-BB-induced CREB depletion in pulmonary artery smooth muscle cells by preventing upregulation of casein kinase 2 α …
- Glucocorticoids repress induction by thiazolidinediones, fibrates, and fatty acids of phosphoenolpyruvate carboxykinase gene expression in adipocytes
- Cardiovascular effects of thiazolidinediones
- Synthesis and structure of substituted bromo and nitrobenzyl benzylidene imidazolidinediones and thiazolidinediones
- Thiazolidinediones exhibit different effects on preadipocytes isolated from rat mesenteric fat tissue and cell line 3T3‐L1 cells derived from mice
- Evaluation of in vitro aldose redutase inhibitory activity of 5-arylidene-2, 4-thiazolidinediones
- Relationship between cumulative dose of thiazolidinediones and clinical outcomes in type 2 diabetic patients with history of heart failure: a population‐based cohort …
- Osteoprotegerin, thiazolidinediones treatment, and silent myocardial ischemia in type 2 diabetic patients
- Thiazolidinediones and cardiovascular disease
- Risk of adverse events with concomitant use of atorvastatin or simvastatin and glucose-lowering drugs (thiazolidinediones, metformin, sulfonylurea, insulin, and …
- Synthesis of spirocyclic thiazolidinediones using ring-closing metathesis and one-pot sequential ring-closing/cross metathesis
- Synthesis of O-prenylated and O-geranylated derivatives of 5-benzylidene2, 4-thiazolidinediones and evaluation of their free radical scavenging activity as well as …
- Diffusion patterns of new anti-diabetic drugs into hospitals in Taiwan: the case of Thiazolidinediones for diabetes
- New therapies in diabetes–thiazolidinediones
- Impact of the socioeconomic status on the probability of receiving formulary restricted thiazolidinediones (TZDs)
- Diabetes and heart failure: the role of thiazolidinediones in managing these partners in crime
- Race, ethnicity, and use of thiazolidinediones among US adults with diabetes
- Regiospecific reduction of 5-benzylidene-2, 4-thiazolidinediones and 4-oxo-2-thiazolidinethiones using lithium borohydride in pyridine and tetrahydrofuran
- Bone metabolism in type 2 diabetes and role of thiazolidinediones
- Synthesis of New 3‐(Substituted Phenacyl)‐5‐[3′‐(4H‐4‐oxo‐1‐benzopyran‐2‐yl)‐benzylidene]‐2,4‐thiazolidinediones and their Antimicrobial Activity
- Novel PPARγ-dependent and independent effects for thiazolidinediones
- Pharmaceutical penetration of new drug and pharmaceutical market structure in Taiwan: hospital-level prescription of thiazolidinediones for diabetes
- Oral combination therapy with thiazolidinediones in type 2 diabetes.
- Type 2 diabetes, psoriasis and thiazolidinediones
- Do thiazolidinediones increase the risk of congestive heart failure and cardiovascular death?
- Thiazolidinediones et insulino-sensibilité: rôle du récepteur nucléaire PPARγ
- Skeletal effects of thiazolidinediones
- Durability of glycemic control: a feature of the thiazolidinediones
- 3D-QSAR studies on a series of 5-arylidine-2, 4-thiazolidinediones as aldose reductase inhibitors: a self-organizing molecular field analysis approach
- Thiazolidinediones increase the number of platelets in immune thrombocytopenic purpura mice via inhibition of phagocytic activity of the reticulo-endothelial system
- Statins but not thiazolidinediones attenuate albumin-mediated chemokine production by proximal tubular cells independently of endocytosis
- Altering PPARγ ligand selectivity impairs adipogenesis by thiazolidinediones but not hormonal inducers
- Synthesis and antihyperglycemic activity of novel 5-(naphthalenylsulfonyl)-2, 4-thiazolidinediones
- Synthesis and biological activity of some new flavonyl-2, 4-thiazolidinediones
- Thiazolidinediones–a new class of oral antidiabetic drugs
- Effects of thiazolidinediones on cardiovascular risk factors
- Medicaid managed care: disparities in the use of thiazolidinediones compared with metformin.
- Down-regulation of uncoupling protein-3 and-2 by thiazolidinediones in C2C12 myotubes
- Cardioprotective effects of thiazolidinediones, peroxisome proliferator-activated receptor-gamma agonists.
- Thiazolidinediones: reactivity of the active methylene group
- What evidence should guide the use of thiazolidinediones?
- Novel euglycemic and hypolipidemic agents. 4. Pyridyl-and quinolinyl-containing thiazolidinediones
- Thiazolidinediones: From antioxidant to neurotherapeutic?
- Thiazolidinediones–a new class of oral antidiabetics
- Thiazolidinediones, a class of anti-diabetic drugs, inhibit Id2 expression through a PPARγ-independent pathway in human aortic smooth muscle cells
- Novel antidiabetic and hypolipidemic agents. 3. Benzofuran-containing thiazolidinediones
- Self-organizing molecular field analysis of 2, 4-thiazolidinediones: A 3D-QSAR model for the development of human PTP1B inhibitors
- Thiazolidinediones and the renal and hormonal response to water immersion-induced volume expansion in type 2 diabetes mellitus
- Different effects of thiazolidinediones on target vessel revascularization with bare metal stents: a meta-analysis
- Synthesis of peptides in aqueous medium. V. Preparation and use of 2, 5-thiazolidinediones (NTA’s). Use of the 13C-H nuclear magnetic resonance signal as …
- Information on thiazolidinediones
- QSAR study of 5-arylidene-2, 4-thiazolidinediones as aldose reductase inhibitors
- Drug class review: Thiazolidinediones
- Acute toxicity assessment of new algicides of thiazolidinediones derivatives, TD53 and TD49, using Ulva pertusa Kjellman
- Thiazolidinediones and their effect on bone metabolism: a review
- Thiazolidinediones and cardiovascular outcomes
- Synthesis and antimicrobial activity of chlorobenzyl benzylidene imidazolidinedione derivatives and substituted thiazolidinediones
- Thiazolidinediones and lowered HDL cholesterol
- Synthesis and aldose reductase inhibitory activity of some new chromonyl-2, 4-thiazolidinediones
- Thiazolidinediones in the treatment of managed care patients with type 2 diabetes
- Efficient gene regulation by PPARγ and thiazolidinediones in skeletal muscle and heart
- 15-Deoxy-Δ12, 14-prostaglandin J2 and thiazolidinediones transactivate epidermal growth factor and platelet-derived growth factor receptors in vascular smooth …
- Thiazolidinediones exert different effects on insulin resistance between dexamethasone-treated rats and wistar fatty rats
- Current developments in thiazolidinediones
- Thiazolidinediones for type 2 diabetes: no evidence exists that pioglitazone induces hepatic cytochrome P450 isoform CYP3A4
- Rosiglitazone, thiazolidinediones and atherosclerosis
- Restoration of impaired p38 activation by insulin in insulin resistant skeletal muscle cells treated with thiazolidinediones
- Synthesis and hypoglycemic activity of some substituted flavonyl thiazolidinedione derivatives—fifth communication: flavonyl benzyl substituted 2, 4-thiazolidinediones
- Are thiazolidinediones good or bad for the heart?
- Use of a PPAR gamma-specific monoclonal antibody to demonstrate thiazolidinediones induce PPAR gamma receptor expression in vitro
- Increased adipose expression of the uncoupling protein-3 gene by thiazolidinediones in Wistar fatty rats and in cultured adipocytes.
- The risk of coronary heart disease in type 2 diabetic patients exposed to thiazolidinediones compared to metformin and sulfonylurea therapy
- Direct attenuation of plasminogen activator inhibitor type-1 expression in human adipose tissue by thiazolidinediones
- Management of type 2 diabetes mellitus. Role of thiazolidinediones.
- Thiazolidinediones and cardiovascular disease: balancing benefit and harm
- An overview and comparison of the thiazolidinediones
- Thiazolidinediones do not reduce target vessel revascularization in diabetic patients undergoing percutaneous coronary intervention
- Regulation of CCAAT/Enhancer Binding Proteinα (C/EBPα) Gene Expression by Thiazolidinediones in 3T3-L1 Adipocytes
- Synthesis and antidiabetic activity of some new chromonyl-2, 4-thiazolidinediones
- Suspected suppression of the INR by thiazolidinediones: interaction between warfarin and TZDs
- Clinical thiazolidinediones as PPARγ ligands with the potential for the prevention of cardiovascular disease in diabetes
- Thiazolidinediones inhibit albumin uptake by proximal tubular cells through a mechanism independent of peroxisome proliferator activated receptor gamma
- Update on the Safety of Thiazolidinediones
- Cardiovascular effects of thiazolidinediones: a review of the literature.
- Type 2 diabetes, thiazolidinediones: bad to the bone?
- Standardized reversed-phase thin-layer chromatographic study of the lipophilicity of five anti-diabetic thiazolidinediones
- Association of diet alone, insulin, sulfonylureas, metformin, and thiazolidinediones with the severity of coronary artery disease in patients with diabetes mellitus
- Improving cardiovascular risk–applying evidence‐based medicine to glucose‐lowering therapy with thiazolidinediones in patients with type 2 diabetes
- Thiazolidinediones may be effective in the prevention of stent thrombosis with DES
- Adiponectin and its response to thiazolidinediones are associated with insulin‐mediated glucose metabolism in type 2 diabetic patients and their first‐degree relatives
- … and ERK1/2 mediated PPARγ-independent event involved in the antiproliferative effect of 15-deoxy-Δ12, 14-prostaglandin J2 and thiazolidinediones in breast cancer …
- Diabetes mellitus, thiazolidinediones and fractures: an unfinished story
- Sitagliptin compared with thiazolidinediones as a third-line oral antihyperglycemic agent in type 2 diabetes mellitus
- Closing the gap between clinical research and clinical practice: can outcome studies with thiazolidinediones improve our understanding of type 2 diabetes?
- Effects of thiazolidinediones on the triad of type 2 diabetes mellitus, insulin resistance and cardiovascular disease
- Thiazolidinediones as PPAR agonists
- Rearrangement of oxazolidinethiones to thiazolidinediones or thiazinanediones and their application for the synthesis of chiral allylic ureas and α-methyl-β-amino …
- Mass spectrometry of some benzylidene imidazolidinediones and thiazolidinediones. II-chlorobenzyl imidazolidinedione and fluoro or chlorobenzyl thiazolidinedione …
- Dicationic ionic liquid mediated synthesis of 5‐arylidine‐2, 4‐thiazolidinediones
- Synthesis of Some Novel 5-Substituted Arylidene–2, 4–Thiazolidinediones as Bioactive Agents
- c-Fos-driven transcriptional activation of transforming growth factor β-1: inhibition of high glucose-induced promoter activity by thiazolidinediones
- Nuclear peroxisome proliferator-activated receptors and thiazolidinediones
- Induction of plasminogen activator inhibitor‐1 (PAI‐1) gene expression in adipocytes by thiazolidinediones
- Predictors of nonpersistence with thiazolidinediones in patients with type 2 diabetes
- The risk of myopathy associated with thiazolidinediones and statins in patients with type 2 diabetes: a nested case-control analysis
- Arterial elasticity and plasma levels of adiponectin and leptin in type 2 diabetic patients treated with thiazolidinediones
- Use of thiazolidinediones does not affect prostate-specific antigen levels in men with diabetes
- Thiazolidinediones may not reduce diabetes incidence in type 1 diabetes
- Use of thiazolidinediones and risk of heart failure in people with type 2 diabetes: a retrospective cohort study: response to Karter et al
- Clinical indications for thiazolidinediones
- Type 2 diabetes, thiazolidinediones, and cardiovascular risk
- Conversion of C2C12 myoblast into adipoblast with thiazolidinediones-A possible basis for Intramuscular fat generation in meat animals
- Myocardial 15-Epi-lipoxin A4 Generation Provides a New Mechanism for the Immunomodulatory Effects of Statins and Thiazolidinediones
- Synthesis and antimicrobial evaluation of some 3-(substituted phenacyl)-5-[4′-(4H-4-oxo-1-benzopyran-2-yl)-benzylidene]-2, 4-thiazolidinediones
- Are thiazolidinediones first-line agents?
- Summarising the use of thiazolidinediones with insulin
- Do thiazolidinediones harm skeletal integrity?
- Studies on 4‐thiazolidinones. I. Cleavage of 3‐Phenyl‐2, 4‐thiazolidinediones with benzylamine and hydrazine
- Design, synthesis and in vitro evaluation of a series thiazolidinediones analogs as PPAR modulators
- Drug Class Review: Thiazolidinediones: Final Report Update 1
- … metabolic syndrome and implications for the management of cardiovascular risk in type 2 diabetes with particular focus on the emerging role of the thiazolidinediones
- The potentially inappropriate prescription of new drug: thiazolidinediones for patients with type II diabetes in Taiwan
- Chiral N-(o-aryl)-thiazolidinediones: Synthesis from rhodanines and investigation on rotational enantiomers by NMR spectroscopy
- Cardiovascular risk-benefit ratio of thiazolidinediones
- Novel euglycemic and hypolipidemic agents: pyridine containing unsaturated thiazolidinediones
- CoMFA and CoMSIA analysis of 2, 4-thiazolidinediones derivatives as aldose reductase inhibitors
- Thiazolidinediones for dementia and mild cognitive impairment
- Improvement of liver function parameters in patients with type 2 diabetes treated with thiazolidinediones
- Thiazolidinediones in type 2 diabetes–have they lived up to expectations?
- Thiazolidinediones anti-inflammatory and anti-atherosclerotic effects in type 2 diabetes mellitus
- Thiazolidinediones alter growth and epithelial cell integrity, independent of PPAR-γ and MAPK activation, in mouse M1 cortical collecting duct cells
- Receptor-independent metabolic effects of thiazolidinediones in astrocytes
- Bypassing the side effects of thiazolidinediones?
- Thiazolidinediones could improve endothelial dysfunction and risk of premature coronary heart disease in HIV-infected patients
- Elevated vitamin D status in postmenopausal women on thiazolidinediones for type 2 diabetes
- Studies on 4-thiazolidinones. IX, The conversion of 5-substituted 2-thioxo-4-thiazolidinones into corresponding 2, 4-thiazolidinediones
- Evaluating the cardiovascular effects of the thiazolidinediones and their place in the management of type 2 diabetes in relation to the metabolic syndrome
- Synthesis of N-substituted 2, 4-thiazolidinediones from oxazolidinethiones
- 4‐Thiazolidinones and 2, 4‐thiazolidinediones from α‐mercaptopropionic acid and carbodiimides
- 5-Aralkylidene-3-isobutyl-2, 4-thiazolidinediones
- Tissue triglyceride levels in type 2 diabetes and the role of thiazolidinediones in reversing the effects of tissue hypertriglyceridemia: review of the evidence in animals …
- One-Pot Multicomponent Synthetic Route for New Quinolidinyl 2, 4-Thiazolidinediones
- An observational study of the effect of two thiazolidinediones on blood lipid levels: Rosiglitazone and pioglitazone in routine clinical practice
- The effect of thiazolidinediones on HDL subfractions
- Ionic liquid-accelerated N-arylation of 5-arylidene-2, 4-thiazolidinediones with diaryliodonium salts
- Clinical difference between thiazolidinediones and biguanides
- Regulation of uncoupling protein-2 mRNA in L6 myotubules: I: Thiazolidinediones stimulate uncoupling protein-2 gene expression by a mechanism requiring ongoing …
- The transcription factor Fos-related antigen 1 is induced by thiazolidinediones during differentiation of 3T3-L1 cells
- Thiazolidinediones as potent inducers of hepatocyte growth factor
- Thiazolidinediones and the risk of nontraumatic fractures in patients with diabetes
- Effect of thiazolidinediones on insulin resistance and cardiovascular risk factors
- Synthesis and antidiabetic activity of some new furochromonyl-2, 4-thiazolidinediones
- Thiazolidinediones and salivary gland enlargement
- Expression of uncoupling protein-3 mRNA in rat skeletal muscle is acutely stimulated by thiazolidinediones: an exercise-like effect?
- Management of type 2 diabetes with thiazolidinediones: link between β-cell preservation and durability of response
- Macular edema and thiazolidinediones
- On the Reactivity of the Exocyclic Double Bond in 5-Arylidene-3-aryl-2, 4-thiazolidinediones; Their Reaction with Diazoalkanes, p-Thiocresol and Piperidine
- Thiazolidinediones associated with recurrent pleural effusions post coronary artery bypass surgery
- In vitro aldose reductase inhibitory activity of some flavonyl-2, 4-thiazolidinediones
- Mass Spectrometry of Some Benzylidene Imidazolidinediones and Thiazolidinediones. III-Positive and Negative Electron Impact Mass Spectra of Chlorobenzyl …
- Thiazolidinediones and PPARgamma system in repair of liver damage
- Thiazolidinediones for elderly patients with Type 2 diabetes: safe or not?
- Thiazolidinediones for Diabetes Mellitus: Considerations for Reimbursements by Third-Party Payors
- Enhancing insulin action: From chemical elements to thiazolidinediones
- Thiazolidinediones increased risk for heart failure, myocardial infarction, and death in older patients with type 2 diabetes
- Constructing an algorithm for managing type 2 diabetes. Focus on role of the thiazolidinediones.
- The thiazolidinediones: a new class of antidiabetic agents
- Regulation of MMP-1 expression in vascular endothelial cells by insulin sensitizing thiazolidinediones
- Improving management of type 2 diabetes mellitus: 5. Thiazolidinediones
- Type 2 Diabetes: Uses of thiazolidinediones and insulin
- Thiazolidinediones and cardiovascular risk: Will the evidence so far available modify treatment strategies for type 2 diabetes?
- Thiazolidinediones in cardiovascular risk in type 2 diabetes mellitus
- Effect of aspirin use on thiazolidinediones and cardiovascular events
- Fractures, heart failure and fears of myocardial ischaemia: has the RECORD stuck for rosiglitazone and the thiazolidinediones?
- Combination therapy of angiotensin receptor blocker with statin or thiazolidinediones as promising therapeutic strategy for metabolic syndrome and …
- The effect of PPAR gamma agonists thiazolidinediones on eosinophil function
- Thiazolidinediones and the risk of nontraumatic fractures in patients with diabetes: in reply
- Thiazolidinediones could be an effective treatment for HIV-associated progressive multifocal leukoencephalopathy
- Risk of heart failure with the use of thiazolidinediones within a medicaid population
- A lesson in moderation: applying pharmacodynamics to clarify the relationship between thiazolidinediones and adverse vascular outcomes in type 2 diabetes
- Thiazolidinediones increase fracture risk
- American Diabetes Association 60th Scientific Sessions, 2000: thiazolidinediones, obesity, and related topics
- How beneficial are thiazolidinediones for diabetes mellitus?
- … Reagents. XXII. Action of Organomagnesium Compounds on 2-Mercapto-4-arylidene-5-thiazolidones and on 4-Arylidene-2, 5-thiazolidinediones. Reaction of 2 …
- Detrimental action of thiazolidinediones on bone
- Mass Spectrometry of Some Bromophenacyl Thiothiazolidinones and Thiazolidinediones
- Incidence of cardiovascular events in which 2 thiazolidinediones are used as add-on treatments for type 2 diabetes mellitus in a Taiwanese population
- Implication for thiazolidinediones (TZDs) as novel potential anti-inflammatory drugs
- The place of thiazolidinediones in the treatment of type 2 diabetes
- Substituted thiazolidinediones and thioxothiazolidinones: synthesis and structure
- Effect of thiazolidinediones (TZDs) on endothelial cell growth and secretion of endothelium-derived vasoactive substances-potential protective action of TZDs on …
- Unravelling the antidiabetic mechanisms of the thiazolidinediones
- Thiazolidinediones and slowing the progression of diabetes.
- Thiazolidinediones in peritoneal dialysis patients
- Effects of thiazolidinediones on serum lipoproteins
- The effects of thiazolidinediones on blood pressure control among different populations–a meta-analysis
- Thiazolidinediones are not associated with increased risk of heart failure hospitalizations in ambulatory patients with diabetes mellitus and heart failure
- Dyslipidemia in type 2 diabetes and the effects of thiazolidinediones
- Association between the use of thiazolidinediones and the risk of cancer in diabetic patients
- Activation of PPAR [Gamma] Inhibits Macrophage Proliferation and Migration: Possible Therapeutic Effectiveness of Thiazolidinediones on Diabetic Vascular …
- Thiazolidinediones in NASH An Odd Couple Meant To Be?
- What is the future of thiazolidinediones (TZDs) after market introduction of inhaled insulin?
- Substituted imidazolidinediones and thiazolidinediones: synthesis, structure and cytotoxic activity
- Combination of nateglinide with thiazolidinediones in Type 2 diabetes
- Evaluation of Thiazolidinediones on Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus: A Systematic Review
- Are thiazolidinediones associated with an increased risk of heart failure and cardiovascular death?
- Modulation of cardiac fibroblast function by thiazolidinediones with a focus on the role of LOX-1.
- Current management of type 2 diabetes: Why thiazolidinediones should be the cornerstone of therapy
- Thiazolidinediones
- Synthesis and antifungal activity of chlorobenzyl benzylidene thiazolidinediones and substituted of imidazolidinediones
- The impact of thiazolidinediones on microalbuminuria in adults with type 2 diabetes mellitus: a systematic review
- Thiazolidinediones regulate expression of proteins involved in triglyceride storage and fatty acid oxidation in 3T3-L1 pre-adipocytes
- Thiazolidinediones in heart failure: slippery when wet
- A Retrospective Review of Thiazolidinediones with Development of a Troglitazone Conversion Protocol
- Synthesis and antihyperglycemic activity of novel flavonyl 2, 4-thiazolidinediones
- Possible vascular-protective effects of antidiabetic agents such as the thiazolidinediones (TZDs).
- Insulinotropic activity of chromonyl-2, 4-thiazolidinediones
- Thiazolidinediones exert a hypotriglyceridemic effect by a distinct, but complementary mechanism relative to fibrates
- Synthesis of polymeric thiazolidinediones and L-ascorbic acid towards the development of insulin-sensitizer
- SYNTHESIS AND EVALUATION OF NEWER QUINOLINE DERIVATIVES OF THIAZOLIDINEDIONES FOR THEIR ANTIDIABETIC ACTIVITY L. SRIKANTH, N …
- Organic reactions in ionic liquids: ionic liquid-accelerated facile synthesis of 3-alkyl-2, 4-thiazolidinediones
- Drugs for diabetes: Part 3 thiazolidinediones
- Antioxidative activities of thiazolidinediones and dihydropyridine-type calcium antagonists
- Thiazolidinediones and the Risk of Incident Congestive Heart Failure Among Patients With Type 2 Diabetes Mellitus: A Population-Based Nested Case-Control Study
- Information on thiazolidinediones
- Trends in management of type 2 diabetes: role of thiazolidinediones
- Thiazolidinediones—the Ongoing Debate
- … of uncoupling protein-2 mRNA in L6 myotubules: II: thyroid hormone amplifies stimulation of uncoupling protein-2 gene by thiazolidinediones and other peroxisome …
- Opposite effects of two thiazolidinediones, ciglitazone and troglitazone, on proteinase-activated receptor-1-triggered prostaglandin E2 release
- Comparative study of thiazolidinediones in clinical use
- Recent trends in PPARgamma agonist development of thiazolidinediones and non-thiazolidinediones
- Thiazolidinediones: a long way to clinical practice
- Thiazolidinediones and Bone
- Proper usage of thiazolidinediones
- Thiazolidinediones.(Medication Update)
- Effects of Thiazolidinediones on Coronary Artery Disease
- ADOPT: evidence for early use of thiazolidinediones
- Thiazolidinediones and type 2 diabetes
- Cardiovascular side effects of thiazolidinediones
- Thiazolidinediones and insulin resistance
- Potential Cardiovascular Effects Of Thiazolidinediones
- Effect of Thiazolidinediones on Glycemia
- The Truth about Lipid Effects of the Thiazolidinediones
- No increase in HF risk or mortality with thiazolidinediones
- Role of insulin resistance with the evidence from thiazolidinediones
- Thiazolidinediones: Cardiovascular friend or foe
- Impact of thiazolidinediones on cardiovascular disease risk factors
- Breaking insulin resistance with thiazolidinediones
- Drug Class Review: Thiazolidinediones
- Thiazolidinediones may increase risk of heart failure
- Thiazolidinediones increase fracture risk in both sexes
- Thiazolidinediones and reduced bone density
- Synthetic use of the ribosyl derivatives of 2, 4-and 2, 5-thiazolidinediones
- Do thiazolidinediones increase the risk of cardiovascular events?
- Thiazolidinediones–Emerging Evidence on Bone Formation
- Thiazolidinediones Appear Safe for Diabetic Eyes
- Metformin and thiazolidinediones
- Insulin sensitizer drugs, thiazolidinediones: current state and prospect
- The effect of thiazolidinediones on leucocytes in type II diabetic patients
- Active pharmaceutical ingredient focus: Thiazolidinediones
- Thiazolidinediones associated with increased fracture risk
- Thiazolidinediones and cardiovascular outcomes in type 2 diabetes
- Obesity, insulin resistance and the implication of thiazolidinediones
- Thiazolidinediones in the treatment of type 2 diabetes
- Precautions for use and contraindications of thiazolidinediones. A cardiologist opinion
- Differences between Thiazolidinediones—Do the Lipid Effects Really Matter?
- Rosiglitazone and the thiazolidinediones: A changing context
- How about the effect of thiazolidinediones in diabetic nephropathy?
- Microwave mediated synthesis and antifungal activity of some 5-benzylidene-2, 4-thiazolidinediones
- Macular Edema and Thiazolidinediones—Reply
- Thiazolidinediones And Type 2 Diabetes Mellitus Proven And Potential Benefits A Review
- Thiazolidinediones in the Treatment of Type 2 Diabetes: A Clinician’s Perspective
- Severe Cholestatic Hepatitis caused by Thiazolidinediones
- Introduction: the role of the thiazolidinediones in the cardiovascular risk management of type 2 diabetes
- Thiazolidinediones inhibit liver regeneration
- Heart failure, diabetes and the thiazolidinediones: an unfolding story
- REGIOSPECIFIC SYNTHESES OF α-GLUTAMYL PEPTIDES VIA 2, 5-THIAZOLIDINEDIONES. PART III.
- Effect of thiazolidinediones on early retinopathy in rats with experimental diabetes
- Are Thiazolidinediones Superior to Standard Therapy in the Treatment of Type 2 Diabetes?
- THE EFFECTS OF THIAZOLIDINEDIONES ON BONE MINERAL DENSITY IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
- Thiazolidinediones Tied to Increased Fracture Risk
- Combination of Metformin and Thiazolidinediones in Type 2 Diabetes Mellitus-A Review
- Thiazolidinediones and Diabetic Macular Edema: Is There an Association?
- The Molecular Mechanisms Underlying the Pro-Inflammatory Actions of Thiazolidinediones (TZDs) in Human Macrophages
- Effects of Thiazolidinediones on Vascular Reactivity and Endothelial Dysfunction
- Persistence rate with thiazolidinediones compared with other antihyperglycemic agents
- Fluid retention with thiazolidinediones in diabetic heart failure
- Oral thiazolidinediones increase feed intake and growth in sheep
- Molecular characterization of insulin resistance in the adipose tissue and the effects of thiazolidinediones
- Thiazolidinediones linked to bone loss in diabetic women
- Post-Entry Market Analysis of New Drug for Diabetes: Penetration and Concentration of Thiazolidinediones (TZD)
- Association Between Use of Thiazolidinediones and Costs of Heart Failure in Patients with Type 2 Diabetes.
- Fracture Risk Spikes With Thiazolidinediones
- Thiazolidinediones Improve Asthma Control In Diabetic Asthmatics
- Thiazolidinediones combined with metformin in treatment of polycystic ovary syndrome: a systematic review
- PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA LIGANDS: THIAZOLIDINEDIONES: 502
- Thiazolidinediones as selective algicides against harmful red-tide algae
- Pharmaceuticals preparations containing thiazolidinediones for the treatment or prevention of IP-10 mediated diseases.
- Oral bisphosphonates improve the bone mineral density in men with diabetes with or without thiazolidinediones
- Effect of Thiazolidinediones Administration on Neurochemical Composition of MPG Neurons Related to Erection in OLETF Rat
- Divergent Effects of Thiazolidinediones on Glucose Transport and Lipid Metabolism in Human Skeletal Muscle Cells
- Thiazolidinediones (TZDs) downregulate Wnt/β-catenin signaling via multiple mechanisms in breast cancer cells
- Meta-analysis of the Effect of Thiazolidinediones on Restenosis After Coronary Artery Stenting in Patients with or Without Diabetes Mellitus
- Do Thiazolidinediones or Statins Suppress Post-Cardiothoracic Surgery Atrial Fibrillation in Diabetics?
- Unraveling the effects of Thiazolidinediones and peroxisome proliferator-activated receptor gamma 1 on ovarian cancer
- Thiazolidinediones Inhibit Vasoactive Agent-induced [Ca. sup. 2+] Mobilization and Cell Proliferation in Vascular Smooth Muscle Cells
- Thiazolidinediones Alter Lipid Bilayer Properties and Native Voltage-Gated Sodium Channel Function
- Glucosamine Induced Insulin Resistance in 3T3L1 Adipocytes is Not Prevented by Thiazolidinediones
- Do thiazolidinediones exert their insulin-sensitizing effect through the suppression of free Fatty acids?
- The effects of glycemic control and thiazolidinediones on the risk of congestive heart failure among patients with type 2 diabetes
- Thiazolidinediones decrease vascular endothelial growth factor (VEGF) production by human luteinized granulosa cells in vitro
- Thiazolidinediones on Insulin Resistance and Insulin Secretion in Obese Diabetic OLETF Rats
- The Anti-proliferative Effects of Thiazolidinediones and Non-steriodal Anti-inflammatory Drugs on Androgen-independent Prostate Cancer
- Appropriateness of the use of Thiazolidinediones for the treatment of Type 2 Diabetes Mellitus at the Southern Arizona Veterans Affairs Hospital
- The influence of thiazolidinediones on marbling in pigs: in vitro studies of muscle stromal-vascular cells from fetal and young pigs and in vivo studies of growing pigs
- Insights on distinct pathways of thiazolidinediones (PPARc ligand)-promoted apoptosis in TRAIL-sensitive or-resistant malignant urothelial cells
- Thiazolidinediones Attenuate Epithelial-Mesenchymal Transition And Pro-fibrotic Functions In Human Alveolar Epithelial Cells And Lung Fibroblasts
- Type 2 diabetes mellitus: Which place for thiazolidinediones in the therapeutic strategy?
- Effects of Thiazolidinediones on CETP/ApoB-100 Double Transgenic Mice Made Obese and Insulin Resistant by High Fat/High Carbohydrate Feeding
- Synthesis and evaluation of antitumor activity of 5-[2-(3, 5-diaryl-4, 5-dihydro-pyrazol-1-yl)-2-oxo-ethylidene]-2, 4-thiazolidinediones
- Govindarajan R, Ratnasinghe L, Simmons DL, Siegel ER, Midathada MV, Kim L, Kim PJ, Owens RJ, Lang NP: Thiazolidinediones and the risk of lung, prostate, and …
- Thiazolidinediones (TZDs) Inhibit the Expression of Pro-Angiogenic ELR+ CXC Chemokines in Non-Small Cell Lung Cancer (NSCLC) Cells Via a PPAR-γ …
- Thiazolidinediones (PPAR [Gamma] Agonists) but Not PPAR [Alpha] Agonists Rapidly Increase IRS-2 Gene Expression in 3T3-L1 Adipocytes
- Thiazolidinediones Regulate Internal Ribosome Entry Site Dependent Translation of Insulin-Like Growth Factor-1 Receptor in Human Aortic Smooth Muscle Cells.
- … , Prague, Czech Republic OBJECTIVE: Czech guidelines recommend additional therapy with sulfonylurea, insulin or thiazolidinediones (TZD) after met
- Differential regulation of stearoyl-CoA desaturase expression and activity by thiazolidinediones, steroid hormones and fatty acid analogs using the mouse 3T3 …
- … congenital partial lipodystrophy without lamin A/C and PPARγ mutations (Köbberling type or variety): A long-term follow-up regarding the efficacy of thiazolidinediones …
- Thiazolidinediones (Pioglitazone) Blocks P. gingivalis-and F. nucleatum-, but not E. coli-Lipopolysaccharide (LPS)-induced interleukin-6 (IL-6) Production in …
- The effect of thiazolidinediones on lipoprotein metabolism: A double blind randomised placebo controlled trial using stable isotopes to investigate the effect of …
- Pathological Gambling Associated with Drug Therapy?: Blood Dyscrasias Associated with Thiazolidinediones: Olanzapine Can Cause Metabolic Problems if Used in …
- Investigation of the reactivity and tautomerism of azolidines. 41. Reaction of 5-benzylidene-2, 4-thiazolidinediones with formaldehyde
- P2-202 Thiazolidinediones are associated with regression of hepatosteatosis in people with type 2 diabetes: the Edinburgh type 2 diabetes study
- 1058 INSIGHTS ON PATHWAYS OF THIAZOLIDINEDIONES-PROMOTED APOPTOSIS IN “TUMOR NECROSIS FACTOR-RELATED APOPTOSIS INDUCING LIGAND …
- Regulation of the Uncoupling Protein-3 Gene Expression by Thiazolidinediones
- 8 Effects of Thiazolidinediones
- Thiazolidinediones: the forgotten diabetes medications
- Thiazolidinediones as antidiabetic agents: A critical review
- Thiazolidinediones and the promise of insulin sensitization in type 2 diabetes
- Thiazolidinediones
- Thiazolidinediones and PPARγ agonists: time for a reassessment
- Risk of fracture with thiazolidinediones: an updated meta-analysis of randomized clinical trials
- Thiazolidinediones are acute, specific inhibitors of the mitochondrial pyruvate carrier
- The current role of thiazolidinediones in diabetes management
- Chemotherapy and chemoprevention by thiazolidinediones
- Cancer risk for patients using thiazolidinediones for type 2 diabetes: A meta‐analysis
- Thiazolidinediones and advanced liver fibrosis in nonalcoholic steatohepatitis: a meta-analysis
- Thiazolidinediones and cancer: results of a meta-analysis of randomized clinical trials
- Thiazolidinediones and associated risk of bladder cancer: a systematic review and meta‐analysis
- Association of thiazolidinediones with liver cancer and colorectal cancer in type 2 diabetes mellitus
- Use of thiazolidinediones and the risk of bladder cancer among people with type 2 diabetes: a meta-analysis
- Association between longer therapy with thiazolidinediones and risk of bladder cancer: a cohort study
- Understanding contemporary use of thiazolidinediones: an analysis from the diabetes collaborative registry
- Therapeutic actions of the thiazolidinediones in Alzheimer’s disease
- Do thiazolidinediones still have a role in treatment of type 2 diabetes mellitus?
- Metformin and thiazolidinediones are associated with improved breast cancer-specific survival of diabetic women with HER2+ breast cancer
- An update on the current and emerging use of Thiazolidinediones for type 2 diabetes
- The effect of thiazolidinediones on bone mineral density and bone turnover: systematic review and meta-analysis
- A new dawn for the use of thiazolidinediones in cancer therapy
- Thiazolidinediones and edema: recent advances in the pathogenesis of thiazolidinediones-induced renal sodium retention
- Adiponectin as a target for the treatment of nonalcoholic steatohepatitis with thiazolidinediones: a systematic review
- Thiazolidinediones and PPAR orchestra as antidiabetic agents: From past to present
- Thiazolidinediones can prevent new onset atrial fibrillation in patients with non-insulin dependent diabetes
- Thiazolidinediones and Parkinson disease: a cohort study
- Sex and BMI alter the benefits and risks of sulfonylureas and thiazolidinediones in type 2 diabetes: a framework for evaluating stratification using routine clinical and …
- Are thiazolidinediones a preferred drug treatment for type 2 diabetes?
- An uncatalyzed aldol reaction of thiazolidinediones
- Thiazolidinediones for nonalcoholic steatohepatitis: A meta-analysis of randomized clinical trials
- Mitochondrial target of thiazolidinediones
- A review on thiazolidinediones and bladder cancer in human studies
- The journey of thiazolidinediones as modulators of PPARs for the management of diabetes: a current perspective
- The metabolic syndrome, thiazolidinediones, and implications for intersection of chronic and inflammatory disease
- Risk of fracture with thiazolidinediones: an individual patient data meta-analysis
- Effect of thiazolidinediones and insulin on cognitive outcomes in ACCORD-MIND
- Thiazolidinediones are associated with a reduced risk of COPD exacerbations
- Thiazolidinediones induce osteocyte apoptosis by a G protein-coupled receptor 40-dependent mechanism
- Site-specific chemical modification of peptide and protein by thiazolidinediones
- Thiazolidinediones under preclinical and early clinical development for the treatment of Parkinson’s disease
- Targeting peroxisome proliferator-activated receptors using thiazolidinediones: strategy for design of novel antidiabetic drugs
- Role of thiazolidinediones, insulin sensitizers, in non‐alcoholic fatty liver disease
- Risk of stroke with thiazolidinediones: a ten-year nationwide population-based cohort study
- Pharmacogenomics and pharmacogenetics of thiazolidinediones: role in diabetes and cardiovascular risk factors
- The use of metformin, insulin, sulphonylureas, and thiazolidinediones and the risk of fracture: systematic review and meta‐analysis of observational studies
- Risk of fracture with thiazolidinediones: disease or drugs?
- Thiazolidinediones: an in–depth study of their synthesis and application to medicinal chemistry in the treatment of diabetes mellitus
- Thiazolidinediones partially reverse the metabolic disturbances observed in Bscl2/seipin-deficient mice
- Pleiotropic effects of thiazolidinediones: implications for the treatment of patients with type 2 diabetes mellitus
- Thiazolidinediones for plaque psoriasis: a systematic review and meta-analysis
- Synthesis, biological evaluation and molecular modeling studies of some novel thiazolidinediones with triazole ring
- Novel potential artificial MRSA DNA intercalators: Synthesis and biological evaluation of berberine-derived thiazolidinediones
- Thiazolidinediones and the risk of asthma exacerbation among patients with diabetes: a cohort study
- Efficacy and safety of once-weekly semaglutide versus once-daily sitagliptin as an add-on to metformin, thiazolidinediones, or both, in patients with type 2 diabetes …
- Effects of thiazolidinediones on polycystic ovary syndrome: a meta-analysis of randomized placebo-controlled trials
- Variation in association between thiazolidinediones and heart failure across ethnic groups: retrospective analysis of large healthcare claims databases in six …
- CYP2C8 and SLCO1B1 Variants and Therapeutic Response to Thiazolidinediones in Patients With Type 2 Diabetes
- Ethylenic conjugated coumarin thiazolidinediones as new efficient antimicrobial modulators against clinical methicillin-resistant Staphylococcus aureus
- SP1-independent inhibition of FOXM1 by modified thiazolidinediones
- Comparative efficacy of oral insulin sensitizers metformin, thiazolidinediones, inositol, and berberine in improving endocrine and metabolic profiles in women …
- … thiazolidinedione analog reduces a negative impact on bone and mesenchymal stem cell properties in obese mice compared to classical thiazolidinediones
- Thiazolidinediones and risk of colorectal cancer in patients with diabetes mellitus: A meta-analysis
- Efficacy and safety of thiazolidinediones in diabetes patients with renal impairment: a systematic review and meta-analysis
- Thiazolidinediones attenuate lipolysis and ameliorate dexamethasone-induced insulin resistance
- Insulin sensitizing and anti-inflammatory effects of thiazolidinediones are heightened in obese patients
- Pyrrolidinediones reduce the toxicity of thiazolidinediones and modify their anti-diabetic and anti-cancer properties
- Thiazolidinediones are associated with a decreased risk of atrial fibrillation compared with other antidiabetic treatment: a nationwide cohort study
- The role of thiazolidinediones in hepatocellular carcinoma risk reduction: a population-based cohort study in Taiwan
- Design, synthesis, and biological evaluation of novel thiazolidinediones as PPARγ/FFAR1 dual agonists
- Effects of three thiazolidinediones on metabolic regulation and cold-induced thermogenesis
- The effects of thiazolidinediones on human bone marrow stromal cell differentiation in vitro and in thiazolidinedione-treated patients with type 2 diabetes
- Association between colorectal cancer and thiazolidinediones administration in a case-control study
- Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: In-silico studies, synthesis, and biological evaluation
- Methylene thiazolidinediones as alkylation reagents in catalytic C–H functionalization: Rapid access to glitazones
- Increased circulating adiponectin in response to thiazolidinediones: investigating the role of bone marrow adipose tissue
- Use of thiazolidinediones and risk of osteoporotic fracture: disease or drugs?
- Thiazolidinediones reduce the risk of hepatocellular carcinoma and hepatic events in diabetic patients with chronic hepatitis B
- Thiazolidinediones improve flow-mediated dilation: a meta-analysis of randomized clinical trials
- Risk of bias in systematic reviews of non-randomized studies of adverse cardiovascular effects of thiazolidinediones and cyclooxygenase-2 inhibitors …
- Use of thiazolidinediones and the risk of colorectal cancer in patients with diabetes: a nationwide, population-based, case-control study
- Deciphering the roles of thiazolidinediones and PPARγ in bladder cancer
- Antidiabetic drugs for Alzheimer’s and Parkinson’s diseases: Repurposing insulin, metformin, and thiazolidinediones
- Thiazolidinediones promote axonal growth through the activation of the JNK pathway
- Capsaicin up-regulates pro-apoptotic activity of thiazolidinediones in glioblastoma cell line
- Variable modulation by cytokines and thiazolidinediones of the prototype Th1 chemokine CXCL10 in anaplastic thyroid cancer
- Pharmacological strategies for insulin sensitivity in obesity and cancer: thiazolidinediones and metformin
- Effects of Thiazolidinediones on metabolism and cancer: Relative influence of PPARγ and IGF-1 signaling
- Synthesis and structure–activity-relationship studies of thiazolidinediones as antiplasmodial inhibitors of the Plasmodium falciparum cysteine protease falcipain-2
- Thiazolidinediones abrogate cervical cancer growth
- Effects of first-line diabetes therapy with biguanides, sulphonylurea and thiazolidinediones on the differentiation, proliferation and apoptosis of islet cell …
- The direct effect of lobeglitazone, a new thiazolidinedione, on pancreatic beta cells: a comparison with other thiazolidinediones
- Mechanistic insights into the augmented effect of bone marrow mesenchymal stem cells and thiazolidinediones in streptozotocin-nicotinamide induced …
- Thiazolidinediones and Glucagon‐Like Peptide‐1 Receptor Agonists and the Risk of Nonalcoholic Fatty Liver Disease: A Cohort Study
- Thiazolidinediones and risk of atrial fibrillation among patients with diabetes and coronary disease
- Synthesis of Chiral Hydantoins and Thiazolidinediones via Iridium‐Catalyzed Asymmetric Hydrogenation
- Use of thiazolidinediones and the risk of elective hip or knee replacement: a population based case–control study
- PPARγ-Independent side effects of thiazolidinediones on mitochondrial redox state in rat isolated hearts
- Design, synthesis, biological evaluation and molecular modelling studies of novel diaryl substituted pyrazolyl thiazolidinediones as potent pancreatic lipase inhibitors
- The rise and fall of the thiazolidinediones: impact of clinical evidence publication and formulary change on the prescription incidence of thiazolidinediones
- The role of thiazolidinediones in the amelioration of nonalcoholic fatty liver disease: a systematic review
- Use of thiazolidinediones and risk of hip fracture in old people in a case–control study in Taiwan
- Identification of oxazolidinediones and thiazolidinediones as potent 17β-hydroxysteroid dehydrogenase type 3 inhibitors
- Association of hepatocellular carcinoma with thiazolidinediones use: A population-based case-control study
- Thiazolidinediones in the treatment of HIV/HAART-associated lipodystrophy syndrome
- Design, synthesis, and molecular docking studies of thiazolidinediones as PPAR‐γ agonists and thymidylate synthase inhibitors
- New thiazolidinediones affect endothelial cell activation and angiogenesis
- Double-edged swords: diaryl pyrazoline thiazolidinediones synchronously targeting cancer epigenetics and angiogenesis
- Use of thiazolidinediones and risk of bladder cancer: disease or drugs?
- Synthesis and antihyperglycemic evaluation of new 2, 4-thiazolidinediones having biodynamic aryl sulfonylurea moieties
- Benzylidene thiazolidinediones: synthesis, in vitro investigations of antiproliferative mechanisms and in vivo efficacy determination in combination with Imatinib
- Thiazolidinediones lower the risk of pneumonia in patients with type 2 diabetes
- In search of the neuroprotective mechanism of thiazolidinediones in Parkinson’s disease
- Combination therapies with thiazolidinediones are associated with a lower risk of acute exacerbations in new-onset COPD patients with advanced diabetic …
- Antifibrotic effects of the thiazolidinediones in eosinophilic esophagitis pathologic remodeling: a preclinical evaluation
- Binding of thiazolidinediones to the endoplasmic reticulum protein nutrient-deprivation autophagy factor-1
- Density Functional Study on the Cytochrome-Mediated S-Oxidation: Identification of Crucial Reactive Intermediate on the Metabolic Path of Thiazolidinediones
- Thiazolidinediones play a positive role in the vascular endothelium and inhibit plaque progression in diabetic patients with coronary atherosclerosis: A …
- Insulin sensitization therapy and the heart: focus on metformin and thiazolidinediones
- PPARγ-independent activity of thiazolidinediones: a promising mechanism of action for new anticancer drugs?
- Sensitivity and precision of adverse effects search filters in MEDLINE and EMBASE: a case study of fractures with thiazolidinediones
- Lack of longitudinal association between thiazolidinediones and incidence and progression of diabetic eye disease: the ACCORD eye study
- Novel N-phenyl–substituted thiazolidinediones protect neural cells against glutamate-and tBid-induced toxicity
- Cardiovascular, ocular and bone adverse reactions associated with thiazolidinediones: a disproportionality analysis of the US FDA adverse event reporting system …
- Thiazolidinediones as novel upstream therapy for atrial fibrillation in diabetic patients: a review of current evidence
- A novel thiazolidinediones ATZD2 rescues memory deficits in a rat model of type 2 diabetes through antioxidant and antiinflammation
- Thiazolidinediones were associated with higher risk of cardiovascular events in patients with type 2 diabetes and cirrhosis
- AMP-activated protein kinase mediates the antiplatelet effects of the thiazolidinediones rosiglitazone and pioglitazone
- Thiazolidinediones (TZDs)
- Metabonomic profiling revealed an alteration in purine nucleotide metabolism associated with cardiac hypertrophy in rats treated with thiazolidinediones
- Effects of safety warnings and risk management plan for Thiazolidinediones in Taiwan
- Fibroblast growth factor-21 regulates PPARγ activity and the antidiabetic actions of thiazolidinediones
- Thiazolidinediones improve hepatic fibrosis in rats with non‐alcoholic steatohepatitis by activating the adenosine monophosphate‐activated protein kinase signalling …
- Statins, fibrates, thiazolidinediones and resveratrol as adjunctive therapies in sepsis: could mitochondria be a common target?
- Structure–activity analysis of harmful algae inhibition by congeneric compounds: case studies of fatty acids and thiazolidinediones
- Reversible inhibition of vasoconstriction by thiazolidinediones related to PI3K/Akt inhibition in vascular smooth muscle cells
- GIPR expression is induced by thiazolidinediones in a PPARγ-independent manner and repressed by obesogenic stimuli
- How Did Multiple FDA actions affect the utilization and reimbursed costs of thiazolidinediones in US medicaid?
- Association of the Pro12Ala gene polymorphism with treatment response to thiazolidinediones in patients with type 2 diabetes: a meta-analysis
- Thiazolidinediones protect mouse pancreatic β-cells directly from cytokine-induced cytotoxicity through PPARγ-dependent mechanisms
- The medicinal perspective of 2, 4‐thiazolidinediones based ligands as antimicrobial, antitumor and antidiabetic agents: A review
- The impact of thiazolidinediones on the risk for prostate cancer in patients with type 2 diabetes mellitus: a review and meta-analysis
- Antitumor effects of energy restriction-mimetic agents: thiazolidinediones
- Multi-target weapons: diaryl-pyrazoline thiazolidinediones simultaneously targeting VEGFR-2 and HDAC cancer hallmarks
- Homology modeling and explicit membrane molecular dynamics simulation to delineate the mode of binding of thiazolidinediones into FFAR1 and the mechanism of …
- Biphenyl tetrazole-thiazolidinediones as novel bacterial peptide deformylase inhibitors: synthesis, biological evaluations and molecular docking study
- Different sites of actions make different responses to thiazolidinediones between mouse and rat models of fatty liver
- Upregulation of hepatic LRP1 by rosiglitazone: a possible novel mechanism of the beneficial effect of thiazolidinediones on atherogenic dyslipidemia
- Discovery of rhodanine and thiazolidinediones as novel scaffolds for EGFR inhibition: design, synthesis, analysis and CoMSIA studies
- Synthesis, In‐Vitro Evaluation and Molecular Docking Study of N‐Substituted Thiazolidinediones as α‐Glucosidase Inhibitors
- Comparing the effects of insulin glargine and thiazolidinediones on plasma lipids in type 2 diabetes: a patient‐level pooled analysis
- Association of hemoglobin A1c levels with use of sulfonylureas, dipeptidyl peptidase 4 inhibitors, and thiazolidinediones in patients with type 2 diabetes treated with …
- Thiazolidinediones and risk of long-term dialysis in diabetic patients with advanced chronic kidney disease: a nationwide cohort study
- Therapeutic journey of 2, 4-thiazolidinediones as a versatile scaffold: An insight into structure activity relationship
- Differential effects of thiazolidinediones and dipeptidyl peptidase-4 inhibitors on insulin resistance and β-cell function in type 2 diabetes mellitus: a propensity …
- A new series of 2, 4-thiazolidinediones endowed with potent aldose reductase inhibitory activity
- Synthesis, characterization and biological evaluation of some novel 2, 4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents
- Synthesis of New N‐Substituted 5‐Arylidene‐2,4‐thiazolidinediones as Anti‐Inflammatory and Antimicrobial Agents
- Thiazolidinediones, alpha-glucosidase inhibitors, meglitinides, sulfonylureas, and hepatocellular carcinoma risk: a meta-analysis
- Correlation between PPARG Pro12Ala Polymorphism and Therapeutic Responses to Thiazolidinediones in Patients with Type 2 Diabetes: A Meta-Analysis
- PPARγ-sparing thiazolidinediones as insulin sensitizers. Design, synthesis and selection of compounds for clinical development
- Efficacy and cardiovascular safety of Thiazolidinediones
- 2, 4-Thiazolidinediones as PTP 1B Inhibitors: A Mini Review (2012-2018)
- Molecular remodeling of the insulin receptor pathway by thiazolidinediones in type 2 diabetes mellitus: A brief review
- Thiazolidinediones (TZDs) affect osteoblast viability and biomarkers independently of the TZD effects on aromatase
- Apolipoprotein E gene polymorphisms affect the efficacy of thiazolidinediones for Alzheimer’s disease: a systematic review and meta-analysis
- Current advances in the biochemical and physiological aspects of the treatment of type 2 diabetes mellitus with thiazolidinediones
- … of PPARγ2 in the Heart Determines Differences in Hypertrophic Cardiomyopathy After Treatment With Different Thiazolidinediones in a Mouse Model of …
- A solvent-free protocol for the green synthesis of 5-arylidene-2, 4-thiazolidinediones using ethylenediamine diacetate as catalyst
- Thiazolidinediones regulate the level of ABC transporters expression on lung cancer cells
- Recent pharmacological developments on rhodanines and 2, 4-thiazolidinediones
- Impact of thiazolidinediones on macular thickness and volume in diabetic eyes
- Antimicrobial activity of thiazolyl benzenesulfonamide-condensed 2, 4-thiazolidinediones derivatives
- Synthesis and structure-activity relationship studies of 2, 4-thiazolidinediones and analogous heterocycles as inhibitors of dihydrodipicolinate synthase
- Clinical outcomes and health care costs combining metformin with sitagliptin or sulphonylureas or thiazolidinediones in uncontrolled type 2 diabetes patients
- Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies
- Sodium-glucose cotransporter protein-2 inhibitors and glucagon-like peptide-1 receptor agonists versus thiazolidinediones for non-alcoholic fatty liver disease: A …
- Long-term therapy with thiazolidinediones and the risk of bladder cancer: A cohort study.
- Decreased risk of liver cancer with thiazolidinediones therapy in patients with type 2 diabetes: Results from a meta-analysis
- Design, synthesis and biological evaluation of novel 5-(imidazolyl-methyl) thiazolidinediones as antidiabetic agents
- Synthesis, HIV-1 RT inhibitory, antibacterial, antifungal and binding mode studies of some novel N-substituted 5-benzylidine-2,4-thiazolidinediones
- Benzisoxazole containing thiazolidinediones as peroxisome proliferator activated receptor-γ agonists: design, molecular docking, synthesis & antidiabetic …
- Incretins and thiazolidinediones in glucose homeostasis and cancer: Role of common polymorphisms
- An insight into the synthesis and SAR of 2, 4-thiazolidinediones (2, 4-TZD) as multifunctional scaffold: a review
- Synthesis of some new 2-amino-6-thiocyanato benzothiazole derivatives bearing 2, 4-thiazolidinediones and screening of their in vitro antimicrobial, antitubercular …
- Different effects of thiazolidinediones on in-stent restenosis and target lesion revascularization after PCI: a meta-analysis of randomized controlled trials
- Keratinocyte growth factor and thiazolidinediones and linolenic acid differentiate characterized mammary fat pad adipose stem cells isolated from prepubertal Korean …
- Activation of a retinoic acid receptor pathway by thiazolidinediones induces production of vascular endothelial growth factor/vascular permeability factor in OP9 …
- Treatment with thiazolidinediones
- Polycystic ovarian syndrome: metformin or thiazolidinediones for cardiovascular risk reduction?
- 5-Arylidene (chromenyl-methylene)-thiazolidinediones: potential new agents against mutant oncoproteins K-Ras, N-Ras and B-Raf in colorectal cancer and …
- Comparison of the Effects of Metformin and Thiazolidinediones on Bone Metabolism: A Systematic Review and Meta-Analysis
- Additive effects of omega-3 fatty acids and thiazolidinediones in mice fed a high-fat diet: triacylglycerol/fatty acid cycling in adipose tissue
- Association of thiazolidinediones with gastric cancer in type 2 diabetes mellitus: a population-based case–control study
- Thiazolidinediones downregulate PPARγ expression via induction of aP2 during mouse 3T3-L1 preadipocyte differentiation
- Novel 2, 4-thiazolidinediones: Synthesis, in vitro cytotoxic activity, and mechanistic investigation
- The effect of exposure to thiazolidinediones on the development of head-and-neck cancer in patients with diabetes mellitus
- Synthesis, biological evaluation and molecular docking studies of novel 3, 5-disubstituted 2, 4-thiazolidinediones derivatives
- Nelfinavir suppresses insulin signaling and nitric oxide production by human aortic endothelial cells: protective effects of thiazolidinediones
- Thiazolidinediones in the treatment of type 2 diabetesmellitus
- … activating receptor gamma–independent attenuation of interleukin 6 and interleukin 8 secretion from primary endometrial stromal cells by thiazolidinediones
- Comparison of sodium-glucose cotransporter-2 inhibitors and thiazolidinediones for management of non-alcoholic fatty liver disease: A systematic review and meta …
- Synthesis and in vitro cytotoxicity evaluation of phenanthrene linked 2, 4-thiazolidinediones as potential anticancer agents
- Hydroxyl ammonium ionic liquid-catalyzed simple and efficient synthesis of 5-arylidene-2, 4-thiazolidinediones under solvent-free conditions
- Synthesis of 5-Alkylidene-2, 4-thiazolidinediones and Rhodanines Promoted by Propylamino-functionalized Nano-structured SBA-15
- Thiazolidinediones and macular edema: comment on “Association between thiazolidinedione treatment and risk of macular edema among patients with type 2 …
- Experimental and theoretical study of substituent effect on 13C NMR chemical shifts of 5-arylidene-2, 4-thiazolidinediones
- Energy restriction mimetic agents to target cancer cells: comparison between 2-deoxyglucose and thiazolidinediones
- Thiazolidinediones Cause Cardiotoxicity via PPARγ-Independent Mechanism
- Thiazolidinediones (TZDs) enhance insulin secretory response via GPR40 and adenylate cyclase (AC)
- Thiazolidinediones as antidiabetic agents-A Review
- Synthesis of newer 5-benzylidene-2, 4-thiazolidinediones as potential antimicrobials
- Clinical effect of thiazolidinediones in subjects with disorders of carbohydrate metabolism in case of polymorphism rs1801282
- Sonochemistry: A good, fast and clean method to promote the synthesis of 5-arylidene-2, 4-thiazolidinediones
- Newer second-line glucose-lowering drugs versus thiazolidinediones on cirrhosis risk among older US adult patients with type 2 diabetes
- Cell cycle synchronisation using thiazolidinediones affects cellular glucose metabolism and enhances the therapeutic effect of 2-deoxyglucose in colon …
- The impact of water molecules on binding affinity of the anti-diabetic thiazolidinediones for catalase: Kinetic and mechanistic approaches
- Nitro-oleic acid protects mice from diet-induced hepatic steatosis and insulin resistance without the adverse side effects of thiazolidinediones
- Effect of thiazolidinediones on adipocytokines and lipid profile in insulin resistant sprague dawley rats
- Intensification with dipeptidyl peptidase-4 inhibitor, insulin, or thiazolidinediones and risks of all-cause mortality, cardiovascular diseases, and severe …
- … , Hypoglycaemic, Hypolipidemic and PPAR γ Agonist Activities of 5‐(2‐Alkyl/aryl‐6‐Arylimidazo [2, 1‐b][1, 3, 4] thiadiazol‐5‐yl) methylene‐1, 3‐Thiazolidinediones
- Substituent and solvent effects on intramolecular charge transfer of 5-arylidene-2, 4-thiazolidinediones
- Design and Synthesis of Echitamine-inspired Hybrid Analogues Containing Thiazolidinediones as Potential Pancreatic Lipase Inhibitors
- Development of new 5-(chromene-3-yl) methylene-2, 4-thiazolidinediones as antimicrobial agents
- Decreased risk of Parkinson’s disease in diabetic patients with thiazolidinediones therapy: An exploratory meta-analysis
- Brown Adipose Tissue PPARγ Is Required for the Insulin-Sensitizing Action of Thiazolidinediones
- Comparative efficacy of thiazolidinediones and metformin for polycystic ovary syndrome
- Synthesis of Bioactive Thioxoimidazolidinones, Oxazolidinones, Thioxothiazolidinones, Thiazolidinediones
- Possible Protective Effects of Thiazolidinediones Antidiabetic Drugs in Colorectal Cancer
- Implications of removing rosiglitazone’s black box warning and restricted access program on the uptake of thiazolidinediones and dipeptidyl peptidase-4 inhibitors …
- Thiazolidinediones Inhibit Mouse Osteoblastic MC3T3-E1 Cell Proliferation in Part Through the Wnt Signaling Pathway
- Insilico Activity Prediction of Thiazolidinediones Derivatives
- Effects of thiazolidinediones on cardiovascular events in patients with type 2 diabetes mellitus after drug-eluting stent implantation: a retrospective cohort study using …
- Solid acid TS-1 catalyst: an efficient catalyst in Knoevenagel condensation for the synthesis of 5-arylidene-2, 4-thiazolidinediones/Rhodanines in aqueous medium
- Simultaneous determination of antidiabetic thiazolidinediones using flow through voltammetric sensor
- Glitazones (thiazolidinediones)
- A review on the clinical safety of thiazolidinediones
- DPP4i, thiazolidinediones, or insulin and risks of cancer in patients with type 2 diabetes mellitus on metformin–sulfonylurea dual therapy with inadequate …
- Preparation of Mg-doped Ce-Zr solid catalysts and their catalytic potency for the synthesis of 5-arylidene-2, 4-thiazolidinediones via Knoevenagel condensation
- Effect of Thiazolidinediones on Renal Outcomes in Diabetic Patients with Microalbuminuria or Macroalbuminuria-A Systematic Review and Meta-analysis
- Antioxidant activities of some new chromonyl-2, 4-thiazolidinediones and chromonyl-2, 4-imidazolidinediones having chromone cores
- Solvent and substituent effect on intramolecular charge transfer in 5-arylidene-3-substituted-2, 4-thiazolidinediones: Experimental and theoretical study
- Insertion of thiazolidinediones into carbon nanotube
- Thiazolidine, thiazolidinediones, TZD
- Phosphoryl Chloride Mediated Synthesis of 5-Arylidene-2, 4-Thiazolidinediones Derivatives via Aromatic Bisulfite Adducts
- Estimation of plasma glucose and creatinine level in alloxan-induced diabetic wistar rats treated with metformin and thiazolidinediones
- Is thiazolidinediones use a factor in delaying the need for insulin therapy in type 2 patients with diabetes? A population-based cohort study
- Correlation between activation of PPARγ and resistin downregulation in a mouse adipocyte cell line by a series of thiazolidinediones
- ZnO nanobelts: an efficient catalyst for synthesis of 5-arylidine-2, 4-thiazolidinediones and 5-arylidine-Rhodanines
- Effects of rosiglitazone on the cardiovascular profile in postmenopausal women without diabetes mellitus: interplay of thiazolidinediones and hormone therapy
- Cushingoid lipodystrophy can be prevented by thiazolidinediones
- … of anti-diabetic therapy on overweight/obesity and dyslipidemia: traditional hypoglycemic agents (metformin, sulfonylureas, thiazolidinediones) versus glucagon-like …
- Unexpected regio-and stereoselective [4+ 3] cycloaddition reaction of azomethine ylides with benzylidene thiazolidinediones: synthesis of pharmacologically active …
- Synthesis and pharmacological evaluation of 2, 4-thiazolidinediones as antidiabetic agents
- Thiazolidinediones versus metformin on improving abnormal liver enzymes in patients with type 2 diabetes mellitus: A meta-analysis
- Thiazolidinediones and reduced risk of incident bacterial abscess in adults with type 2 diabetes: A population‐based cohort study
- Thiazolidinediones: A class of pharmacologically important molecules.
- Effect of hyperglycemia and thiazolidinediones on cardiac angiotensin converting enzyme 2 (ACE2) and neprilysin (NEP) in db/db diabetic mice.
- Chemistry and Applications of Functionalized 2, 4‐Thiazolidinediones
- Molecular docking studies of novel arylidene-2, 4-thiazolidinediones as potential aldose reductase inhibitors
- Differential characterization of myogenic satellite cells with linolenic and retinoic acid in the presence of thiazolidinediones from prepubertal Korean black …
- Physiologically Based Pharmacokinetic Modeling and Simulation of Thiazolidinediones in Patients with Hepatic Impairment
- Chemometric study of retention indices of some thiazolidinediones derivatives in two low polarity stationary phases
- Virtual Screening, Docking, Synthesis and Bioactivity Evaluation of Thiazolidinediones as Potential PPARγ Partial Agonists for Preparation of Antidiabetic Agents
- Ability of two new thiazolidinediones to downregulate proinflammatory cytokines in peripheral blood mononuclear cells from children with asthma
- Role of Galactose, Thiazolidinediones, and NEET proteins in Mitochondrial physiology and therapeutic development.
- Deciphering the Roles of Thiazolidinediones and PPAR in Bladder Cancer
- Design, Synthesis and Antidiabetic Evaluation of New Cyanoquinoloxy Benzylidenyl 2, 4-Thiazolidinediones.
- Assorted applications of N-substituted-2, 4-thiazolidinediones in various pathological conditions
- The effect of Thiazolidinediones on the vascular endothelium and plaque in diabetic patients with coronary atherosclerosis: a meta-analysis
- Synthesis and evaluating anti-inflammatory, antibacterial activity of substituted benzylidene thiazolidinediones
- … : efficient, inexpensive and reusable catalysts for the synthesis of pyrazole derivatives with 2-iminothiazolidin-4-one and 2, 4-thiazolidinediones under solvent-free …
- Synthesis of novel 1, 2, 3-triazoles bearing 2, 4 thiazolidinediones conjugates and their biological evaluation
- Adiponectin versus thiazolidinediones and angiotensin receptor blockers
- Thiazolidinediones and Rheumatoid Arthritis: A Retrospective Cohort Study
- Current drug information: Thiazolidinediones associated with increased risk of bladder cancer among adults with type 2 diabetes
- Heterocyclyl linked phenyl containing Thiazolidinediones and its Cyclic analogs as potential novel Antidiabetic agents
- Clinical Management of Nonalcoholic Steatohepatitis (NASH) With the Use of Thiazolidinediones and the Additive Effect of Thiazolidinediones and a GLP-1 …
- Correction: Risk of death and cardiovascular outcomes with thiazolidinediones: a study with the General Practice Research Database and secondary care data
- The Effect of Thiazolidinediones and SGLT-2 Inhibitors on Minerals, VIT. D3, Blood Glucose and Weight Gain in Wistar Rats Induced with Type 2 Diabetes
- Investigation of substituted thiazolidinediones as corrosion inhibitors on different metals in acidic media
- The Spectrum of Thiazolidinediones against Respiratory Tract Pathogenic Bacteria: An In Vitro and In Silico Approach
- … range of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation, chemotherapy, thiazolidinediones). However, to advance …
- Hypoglycemic and Hypolipidemic Swords: Synthesis and In-vivo Biological Assessment of 5-benzylidene-2, 4-thiazolidinediones
- … of anti-diabetic drugs on risk of fracture in type 2 diabetes mellitus patients: a network meta-analytic synthesis of randomized controlled trials of thiazolidinediones
- The clinical summary of thiazolidinediones in the treatment of T2DM.
- Green Synthesis of 5-Arylidene-2, 4-Thiazolidinediones Over FeAlPO-5 Catalysts
- Effects of Metformin compared to Thiazolidinediones on vascular endothelial function in Polycystic Ovary syndrome: A systematic review
- ROLES OF THIAZOLIDINEDIONES IN TYPE 2 DIABETES MELLITUS TREATMENT AND WEIGHT GAIN
- The effect of diabetes mellitus, insulin, and thiazolidinediones on bone histomorphometry in streptozotocin-induced diabetic postmenopausal wistar rats
- The Use of Thiazolidinediones in Type 2 Diabetic Patients
- Increasing endogenous PPARγ ligands improves insulin sensitivity and protects against diet-induced obesity without side effects of thiazolidinediones
- Are thiazolidinediones effective in the treatment of nonalcoholic steatohepatitis (NASH)?
- Use of thiazolidinediones and risk of bladder cancer: disease or drugs?
- Beneficial Effects of Inhibition of the Mitochondrial Pyruvate Carrier and the Mechanism of Action of Thiazolidinediones
- Exploring off‐target binding of thiazolidinediones and a novel mechanism for restoring insulin sensitivity (854.2)
- Effects of Thiazolidinediones on In-Stent Restenosis: A Review of IVUS Studies
- Thiazolidinediones as selective algicides against harmful algae
- Effects of thiazolidinediones on vascular endothelial function in patients with type 2 diabetes mellitus
- Development of oedema is associated with an improved glycaemic response in patients initiating thiazolidinediones: a MASTERMIND study
- A Retrospective Evaluation of the use of Thiazolidinediones in Patients with Diabetes Mellitus in a Private Hospital in Ras Al Khaimah.
- Comparative efficacy of thiazolidinediones and metformin for polycystic ovary syndrome
- Modulation of visfatin levels by thiazolidinediones in insulin resistant sprague dawley rats
- Substituent effects on chromatographic retention data of 5-arylidene-2, 4-thiazolidinediones in qsar methodology
- Modulation of visfatin levels by thiazolidinediones in insulin resistant sprague dawley rats
- Effect of thiazolidinediones on insulin resistance and reduced-fat liver
- Effect of Thiazolidinediones (Glitazones) groups on Glycemic control and Lipid profile: A Meta-analysis of Randomized Control Trials
- Thiazolidinediones as potential therapeutic agents in atopic eczema
- Thiazolidinediones Promote Axonal Growth through the Activation of the JNK
- In Silico Study on the Interaction of Thiazolidinediones and β-Lactoglobulin by Molecular Dynamics and Docking Approach
- … of diseases (osteoporosis, diabetes, anorexia, cancer) as well as treatments (corticosteroid, radiation, chemotherapy, thiazolidinediones). However, to advance …
- Effect of thiazolidinediones on dislipidemia in patients with metabolic syndrome depending on the gene PPAR-gamma rs1801282 polymorphism
- Influence of esomeprazole on the pharmacodynamic activity of thiazolidinediones (pioglitazone and rosiglitazone) in animal models
- Controlled clinical trial with the combination therapy with metformin, thiazolidinediones, glucagon-like peptide 1 analog in patients with type 2 diabetes and metabolic …
- Clinical Outcomes and Health Care Costs Evaluation of Sulfonamides and Thiazolidinediones Compared with Dipeptidyl Peptidase 4 Inhibitors for the Treatment of …
- Triple Therapy with Dpp4 Inhibitor, Insulin, or Thiazolidinediones and Risks of Cardiovascular Diseases and All-Cause Mortality in Patients with Failed Metformin-SU …
- Thiazolidinediones inhibit airway smooth muscle release of the chemokine CXCL10: in vitro comparison with current asthma therapies
- Thiazolidinediones’ Insulin-Sensitizing Properties Depend on Adiponectin-Mediated Reductions in Certain Ceramide Species
- … between (UCP1-independent) antidiabetic effects (MSDC-0602) and adipogenic and browning-inducing effects (MSDC-0160) of classical thiazolidinediones …
- Thiazolidinediones augment anticancer effects of gemcitabine on human pancreatic cancer cells through PPARδ activation
- Effect of thiazolidinediones: PPAR [gamma] agonists on hormones secretion by cells of human adrenocortical cancer in vitro
- Differential Effects of Thiazolidinediones and Dipeptidyl Peptidase-4 Inhibitors on Insulin Resistance and b-Cell Function in Type 2 Diabetes Mellitus: A …
- Efficacy and Safety of Once-Weekly Semaglutide vs. Sitagliptin as Add-on to Metformin and/or Thiazolidinediones after 56 Weeks in Subjects with Type 2 Diabetes …
- Stratification using gender and body mass index (BMI) can predict side-effect risk in people with Type 2 diabetes initiating thiazolidinediones but not sulphonylureas: a …
- OR14-05 Hepatocyte Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Offsets the Anti-Steatogenic Effects of Thiazolidinediones in Obese Male Mice
- In the article “Incidence of Cardiovascular Events in Which 2 Thiazolidinediones Are Used as Add-on Treatments for Type 2 Diabetes Mellitus in a Taiwanese …
- Synthesis of new 5-(chromene-3-yl) methylene-2, 4-thiazolidinediones
- Synthesis and In-Vitro Anticancer Evaluation of Novel 5-Substituted Thiazolidinediones
- Novel 2, 4-thiazolidinediones: synthesis, in vitro cytotoxic activity, and mechanistic investigation
