MITOHORMESIS
December 8, 2023FNDC5
December 8, 2023
- Advanced glycation end-product cross-link breakers: a novel approach to cardiovascular pathologies related to the aging process
- Cross-link breakers as a new therapeutic approach to cardiovascular disease
- Potential clinical utility of advanced glycation end product cross-link breakers in age-and diabetes-associated disorders
- Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension
- Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein AI
- The cross-link breaker, N-phenacylthiazolium bromide prevents vascular advanced glycation end-product accumulation
- Potential Usefulness of AGE Cross–Link Breakers for Modulating the Progression of AMD
- Advanced glycation end-product cross-link breakers: a novel therapeutic pathway for cardiovascular disease
- Cross-link Breakers and Inhibitors
- Cleavage of in vitro and in vivo formed lens protein cross-links by a novel cross-link breaker
- Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links
- In vitro antiglycation and cross-link breaking activities of Sri Lankan low-grown orthodox orange pekoe grade black tea (Camellia sinensis L)
- Characteristics, formation, and pathophysiology of glucosepane: a major protein cross-link
- Inhibitors and breakers of advanced glycation endproducts (AGEs): a review
- Effect of the age cross-link breaker alagebrium on anterior segment physiology, morphology, and ocular age and rage
- Restraining cross-links responsible for the mechanical properties of collagen fibers: natural and artificial
- Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart
- Therapeutic options to reduce advanced glycation end products in patients with diabetes mellitus: A review
- Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes
- Biochemical process of AGEs formation in complications of hyperglycemia-induced diabetes and its pathological damage effects: A possible target for new drugs
- Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease
- The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin‐induced diabetic rats: Preventive versus curative …
- Crosslink breakers: a new approach to cardiovascular therapy
- AGE, RAGE, and ROS in diabetic nephropathy
- Laser Sub–Fractionation to Assess the Elasticity of Ageing Human Bruch’s Membrane: Reversal Implications for AMD
- Diabetic heart disease
- Advanced glycation end‐products (AGEs) and heart failure: pathophysiology and clinical implications
- Novel cross-link breaker based on zwitterion structure: Synthesis, structure and druggability studies
- Advanced Glycation End Products in Diabetes‐Associated Atherosclerosis and Renal Disease: Interventional Studies
- Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling
- The diabetic myocardium
- Arterial stiffness and cardiovascular therapy
- A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys
- Treating diastolic heart failure with AGE crosslink breakers: thinking outside the heart failure box
- Synthesis and Evaluation of Novel [1,2,4]Triazolo[5,1‐c][1,2,4]‐triazines and Pyrazolo[5,1‐c][1,2,4]triazines as Potential Antidiabetic Agents
- Consensus ensemble neural network modeling of Maillard reaction inhibitors
- Non-enzymatic glycation and oxidative stress in chronic illnesses and diabetes mellitus
- Advanced Glycation End Product Cross‐Linking: Pathophysiologic Role and Therapeutic Target in Cardiovascular Disease
- Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications
- The AGE/RAGE axis in diabetes‐accelerated atherosclerosis
- β‐Amyloid peptide potentiates inflammatory responses induced by lipopolysaccharide, interferon‐γ and ‘advanced glycation endproducts’ in a murine microglia cell …
- Do advanced glycation end products contribute to the development of long-term diabetic complications?
- AGE-RAGE and AGE Cross-link interaction: important players in the pathogenesis of diabetic kidney disease
- Clinical potential of advanced glycation end-product inhibitors in diabetes mellitus
- 925 ARE ADVANCED GLYCATION END PRODUCTS ASSOCIATED WITH MACROVASCULAR DISEASE IN TYPE 2 DIABETES MELLITUS?
- Pharmacological modulation of arterial stiffness
- The Unique Reactivity of N-Phenacyl-Derived Thiazolium Salts Toward α-Dicarbonyl Compounds
- Therapeutic modulation of aortic stiffness
- Screening of herbal medicines from China with inhibitory activity on advanced glycation end products (AGEs) formation (VI)
- Screening of herbal medicines from China and Vietnam with inhibitory activity on advanced glycation end products (AGEs) formation (IV)
- Aging of the Vasculature and Related Systems
- Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
- Clinical studies of advanced glycation end product inhibitors and diabetic kidney disease
- New therapies for advanced glycation end product nephrotoxicity: current challenges
- Diagnosis and treatment of early renal disease in patients with type 2 diabetes mellitus: what are the clinical needs?
- Advanced Glycation Endproducts,(AGEs): Formation, Complication and Pharmacological Evaluation to Its Inhibition
- Fibrosis, enzymatic and non-enzymatic cross-links in hypertensive heart disease
- Advanced glycation end products inhibitor
- Inhibitors of the Maillard reaction and AGE breakers as therapeutics for multiple diseases
- The breakdown of preformed peritoneal advanced glycation end products by intraperitoneal alagebrium
- How drugs influencing central blood pressure prevent atherosclerosis complications?
- Methylglyoxal, oxidative stress, and aging
- The breakdown of pre‐existing advanced glycation end products is associated with reduced renal fibrosis in experimental diabetes
- The impracticality of biomedical rejuvenation therapies: translational and pharmacological barriers
- Molecular basis of arterial stiffening: role of glycation–a mini-review
- The next generation of diabetic nephropathy therapies: an update
- The ultimate AGE inhibitors
- Advanced glycation: implications in tissue damage and disease
- Therapeutic interventions in the glyc (oxid) ation pathway
- Diabetes and arterial stiffening
- Advanced glycation end products and diabetic nephropathy
- The role of advanced glycation end products in progression and complications of diabetes
- Transition metal‐mediated glycoxidation accelerates cross‐linking of β‐amyloid peptide
- Introduction of hyperglycemia and dyslipidemia in the pathogenesis of diabetic vascular complications
- Naturally occurring inhibitors against the formation of advanced glycation end-products
- Effects of chebulic acid on advanced glycation endproducts-induced collagen cross-links
- The deconvolution of diastole
- Large artery stiffness and brain health: Insights from animal models
- Advanced glycation end product interventions reduce diabetes-accelerated atherosclerosis
- Advanced glycation end products
- Functional effects of alagebrium (alt-711)–isolated rat carotid artery
- Natural inhibitors of advanced glycation end‐products
- The advanced glycation end product-lowering agent ALT-711 is a low-affinity inhibitor of thiamine diphosphokinase
- More than genes and cells: drug discovery in the ECM
- What the dead can teach the living: systemic nature of heart failure with preserved ejection fraction
- Advanced glycation end-products and arterial stiffness in hypertension
- Polyclonal antibodies inhibit the glycation‐induced inactivation of bovine Cu, Zn‐superoxide dismutase
- Advanced glycation endproducts—role in pathology of diabetic complications
- The role of advanced glycation end products in the development of atherosclerosis
- The role of advanced glycation end products in various types of neurodegenerative disease: a therapeutic approach
- Uremic toxicity of advanced glycation end products in CKD
- Atherogenesis and Advanced Glycation: Promotion, Progression, and Preventiona
- The role of collagen crosslinks in ageing and diabetes-the good, the bad, and the ugly
- The effects of the Maillard reaction on the physical properties and cell interactions of collagen
- Advanced glycation end products are associated with pulse pressure in type 1 diabetes: the EURODIAB Prospective Complications Study
- A novel improved therapy strategy for diabetic nephropathy: targeting AGEs
- Diabetic cardiomyopathy—What do we know about it?
- Inhibitors of Advanced Glycation End Product (AGE) Formation and Accumulation
- Multiligands/Rage Axis: an Emerging Actor in Tumour Angiogenesis
- Importance of advanced glycation end products in diabetes-associated cardiovascular and renal disease
- Role of glycation in aging
- RAGE: a new pleiotropic antagonistic gene?
- Urinary proteomics in diabetes and CKD
- Advanced glycation end products accumulate in vascular smooth muscle and modify vascular but not ventricular properties in elderly hypertensive canines
- Glycation of high-density lipoprotein in type 2 diabetes mellitus
- The causes and consequences of low levels of high density lipoproteins in patients with diabetes
- Reducing arterial stiffness and wave reflection–Quest for the Holy Grail?
- Role of advanced glycation end products in diabetic nephropathy
- Drug therapy for the cardiac complications of diabetes
- Therapeutic approaches in heart failure with preserved ejection fraction: past, present, and future
- Glycation, carbonyl stress and AGEs inhibitors: a patent review
- Hypertension and diabetes
- Current perspectives on the health risks associated with the consumption of advanced glycation end products: recommendations for dietary management
- Future strategies to prevent renal microvascular disease complications in diabetes
- Molecular targets of diabetic cardiovascular complications
- Prevention of non-enzymatic glycosylation (glycation): Implication in the treatment of diabetic complication
- Pathophysiology, genetic, and therapy of arterial stiffness
- Advanced glycation endproduct crosslink breaker (alagebrium) improves endothelial function in patients with isolated systolic hypertension
- Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells
- Methylglyoxal and advanced glycation endproducts: new therapeutic horizons?
- Left ventricular diastolic dysfunction in dialysis patients assessed by novel speckle tracking strain rate analysis: prevalence and determinants
- Alagebrium (ALT-711) improves the anti-hypertensive efficacy of nifedipine in diabetic-hypertensive rats
- Alagebrium in combination with exercise ameliorates age-associated ventricular and vascular stiffness
- More than genes and cells: Drug discovery in the extracellular matrix (ECM)
- Arterial stiffness, pulse pressure, and cardiovascular disease—is it possible to break the vicious circle?
- Oxidative stress in diabetes and Alzheimer’s disease
- The role of advanced glycation end products in diabetic vascular complications
- New therapeutic avenues for age-related macular degeneration: targeting Bruch’s membrane
- Advanced glycation end products: role in pathology of diabetic cardiomyopathy
- Potential of collagen cross-linking therapies to mediate tendon mechanical properties
- The aging hypertensive heart: a brief update
- Therapeutic effect of combination of alagebrium (ALT-711) and sildenafil on erectile function in diabetic rats
- Blocking Gastrointestinal Absorption of AGEs
- The clinical relevance of ageing
- Induced pluripotent stem (iPS) cells inhibit apoptosis and fibrosis in streptozotocin-induced diabetic rats
- Republished paper: arterial stiffness in chronic kidney disease: causes and consequences
- Mechanisms of Diabetic Complications Nephropathy as Related to Perspectives of Treatment
- Inhibitors of advanced glycation end products (AGEs): potential utility for the treatment of cardiovascular disease
- Anti-AGEing defences against Alzheimer’s disease
- Melatonin is not a carbonyl scavenger
- Below the Radar: Advanced Glycation End Products that Detour “around the side”: Is HbA1c not an accurate enough predictor of long term progression and …
- Newer insights in drugs inhibiting formation and accumulation of advanced glycation end products.
- The effect of an advanced glycation end-product crosslink breaker and exercise training on vascular function in older individuals: a randomized factorial design trial
- Glucose as an agent of post-translational modification in diabetes—New cardiac epigenetic insights
- AGE-RAGE axis blockade in diabetic nephropathy: current status and future directions
- Matrix biology of abdominal aortic aneurysms in diabetes: mechanisms underlying the negative association
- The role of AGEs and AGE inhibitors in diabetic cardiovascular disease
- Stagnation and the critical need for hypertension subtyping
- Does accumulation of advanced glycation end products contribute to the aging phenotype?
- Potential new therapeutic agents for diabetic kidney disease
- The aorta and resistant hypertension
- Targeting advanced glycation with pharmaceutical agents: where are we now?
- Hormetic triggers for intervention in aging, disease and trauma
- Receptor for advanced glycation endproducts and atherosclerosis: from basic mechanisms to clinical implications
- Glycoxidative stress in aging and pathology
- Role of advanced glycation end products in carcinogenesis and their therapeutic implications
- Serum carboxymethyllysine concentrations are reduced in diabetic men with abdominal aortic aneurysms: Health In Men Study
- Decreased plasma levels of soluble receptor for advanced glycation end-products in patients with essential hypertension
- Early-and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics
- Mechanisms Involved in Premature Aging in the Heart—Is There an Implication for Cardiac Surgery?
- The pulsatile component of blood pressure–Its role in the pathogenesis of atherosclerosis
- Role of advanced glycation endproduct (AGE)-receptor for advanced glycation endproduct (RAGE) axis in cardiovascular disease and its therapeutic intervention
- Cardiac fibrosis and aging
- The role of AGEs in cardiovascular disease
- Oxidative stress and aging: is methylglyoxal the hidden enemy?
- Alagebrium chloride, a novel AGE cross linkage breaker, inhibits neointimal proliferation after carotid balloon injury in diabetic animal model
- The question is, my dear watson, why did the dog not bark?: The joslin 50-year medalist study
- Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts
- Inhibition of advanced glycation end-product formation by lutein from Tagetes erecta
- Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein AI
- The therapeutic effect of ALT-711 on erectile function in rats treated with high-level AGEs (advanced glycation end products) containing diet
- Arterial stiffness in diabetes and the metabolic syndrome: a pathway to cardiovascular disease
- Diastolic disturbances in diabetes mellitus
- The Implications of Fruit and Vegetable Consumption in Patients with Diabetes
- Does angiotensin receptor blockade improve outcomes in patients with heart failure and preserved ejection fraction? Results of the I-PRESERVE study
- Reactions in glass ionomer cements: V. Effect of incorporating tartaric acid in the cement liquid
- Soft-tissue wound healing by anti-advanced glycation end-products agents
- Glycative stress and anti-aging: 14. Regulation of Glycative stress. 2. Inhibition of the AGE production and accumulation
- Role of hyperglycemia-induced advanced glycation end product (AGE) accumulation in atherosclerosis
- Decreasing Arterial Stiffness and/or Wave Reflections Independently of Mean Arterial Pressure: Effect of Antihypertensive Drugs (Part 1)
- Dynamic changes in myocardial matrix and relevance to disease: translational perspectives
- Resurrecting the dead (molecules)
- New insights in the pharmacological therapy of arterial hypertension
- Protein glycation: a firm link to endothelial cell dysfunction
- Cellular mechanisms for diastolic dysfunction in the human heart
- Arterial stiffness in chronic kidney disease: an update
- Targeting AGEs signaling ameliorates central nervous system diabetic complications in rats
- Advanced glycation end‐products, anti‐hypertensive treatment and diastolic function in patients with hypertension and diastolic dysfunction
- Inhibition of renin-angiotensin system and advanced glycation end products formation: a promising therapeutic approach targeting on cardiovascular diseases
- Heat stable inhibitors of protein cross-linking from Sri Lankan medicinal plants
- Arterial stiffness, cognitive impairment and dementia: confounding factor or real risk?
- Can you reduce your AGE?: Strategies to prevent AGE accumulation in diabetes
- Are Finger Skin Fluorophores Other Than Advanced Glycation End Products (AGEs) Associated With Impaired Musculoskeletal Properties?
- Advanced glycosylated end products derived from external sources contribute to diabetic complications
- Pyrazolotriazines: biological activities, synthetic strategies and recent developments
- Novel therapeutics for diabetic micro-and macrovascular complications
- Effects of uwhangchungsimwon on arterial stiffness
- Type 2 diabetes—implications for macrovascular mechanics and disease
- Tissue advanced glycation end products are associated with diastolic function and aerobic exercise capacity in diabetic heart failure patients
- Arterial stiffness and coronary ischemic disease
- Heart failure with preserved ejection fraction and future pharmacological strategies: a glance in the crystal ball
- Recent advances in understanding the biochemical and molecular mechanism of diabetic cardiomyopathy
- AGEs bind to mesothelial cells via RAGE and stimulate VCAM-1 expression
- An anti-glycating property roots ethanol and methanol extracts of Withania somnifera on in vitro glycation of elastin protein
- Antihypertensive therapy and de-stiffening of the arteries
- Advanced glycation end products decrease mesangial cell MMP-7: a role in matrix accumulation in diabetic nephropathy?
- Role of Smad1 in diabetic nephropathy: molecular mechanisms and implications as a diagnostic marker
- Role of advanced glycation end products in cardiovascular disease
- Glycated proteome: From reaction to intervention
- Mechanical properties of normal and diseased cerebrovascular system
- Browsed by Tag: senolytics
- Molecular mechanisms of diabetic vascular complications
- Heart failure highlights in 2011
- Long-term exercise training attenuates age-related diastolic dysfunction: association of myocardial collagen cross-linking
- Implication of advanced glycation end products (Ages) and their receptor (Rage) on myocardial contractile and mitochondrial functions
- Cellular mechanisms and consequences of glycation in atherosclerosis and obesity
- Heart failure with preserved ejection fraction: current management and future strategies
- KIOM-79, an inhibitor of AGEs–protein cross-linking, prevents progression of nephropathy in Zucker diabetic fatty rats
- Hyperglycemia and the pathobiology of diabetic complications
- Increased collagen, per se, may not affect left ventricular function in spontaneously hypertensive rats
- Heart failure with preserved ejection fraction: uncertainties and dilemmas
- Comparative study of antioxidant, metal chelating and antiglycation activities of Momordica charantia flesh and pulp fractions.
- Cleaving effect of pomegranate (Punica granatum) extract on crosslink derived from advanced glycation endproducts
- Relationship between tissue glycation measured by autofluorescence and pulse wave velocity in young and elderly non-diabetic populations
- Browsed by Tag: Lysosomes
- Browsed by Tag: allotopic expression
- Browsed by Tag: Lysosomal dysfunction
- Browsed by Tag: Mitochondrial mutations
- SENS: Progress in the Fight Against Age-Related Diseases–Article by Nicola Bagalà and Steve Hill
- Browsed by Tag: MitoSENS crowdfunding campaign
- Browsed by Tag: Kizoo Technology Ventures
- Browsed by Tag: Dr. Kelsey Moody
- Browsed by Tag: Professor Judy Campisi
- Growth factors, AGEing, and the diabetes link in Alzheimer’s disease
- Do advanced glycation end products and its receptor play a role in pathophysiology of hypertension?
- Advanced glycation endproducts: from precursors to RAGE: round and round we go
- Diabetic cardiomyopathy
- Optimal treatment of hypertension in the elderly: A Korean perspective
- Optimal treatment of hypertension with diastolic heart failure
- Receptor for advanced glycation end products and the cardiovascular complications of diabetes and beyond: lessons from AGEing
- From hyperglycemia to diabetic kidney disease: the role of metabolic, hemodynamic, intracellular factors and growth factors/cytokines
- Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress
- Aortic stiffness: current understanding and future directions
- Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging
- 50 Year Medalists’ Biochemistry Clue Researchers to the Source of Complications or” The Question Is, My Dear Watson, Why Did the Dog Not Bark?
- Glycoxidation of biological macromolecules: a critical approach to halt the menace of glycation
- Facts and numbers on epidemiology and pharmacological treatment of heart failure with preserved ejection fraction
- Advanced glycation end-products produced systemically and by macrophages: A common contributor to inflammation and degenerative diseases
- Arterial stiffness in renal patients: an update
- Pathogenesis of elevated peripheral pulse pressure: some reflections and thinking forward
- Treatment and control of high blood pressure in adults
- Arterial Stiffness and Coronary Ischemic
- Inhibition of the receptor for advanced glycation end-products in acute respiratory distress syndrome: a randomised laboratory trial in piglets
- Advanced glycation end products: key players in skin aging?
- Advanced glycation endproducts: activators of cardiac remodeling in primary fibroblasts from adult rat hearts
- Natural products as potential inhibitors of Advanced Glycation Endproducts (AGEs) and modulators of autophagy
- Ultrasonic detection of the anisotropy of protein cross linking in myocardium at diagnostic frequencies
- Mechanisms, pathophysiology, and therapy of arterial stiffness
- Protein glycation during aging and in cardiovascular disease
- Arterial aging: is it an immutable cardiovascular risk factor?
- Concerns about clinical efficacy and safety of warfarin in diabetic patients with atrial fibrillation
- Advanced glycation/glycoxidation endproduct carboxymethyl-lysine and incidence of coronary heart disease and stroke in older adults
- Collagen in its fibrillar state is protected from glycation
- Mechanisms of Diabetic Complications (Nephropathy) as Related to Perspectives of Treatment
- Prehypertension and risk of cardiovascular disease
- Ageing of the conduit arteries
- Valsartan improves arterial stiffness in type 2 diabetes independently of blood pressure lowering
- Investigation of the mechanism (s) involved in decreasing increased fibrinogen activity in hyperglycemic conditions using L-lysine supplementation
- Left ventricular hypertrophy regression and allopurinol: more questions than answers
- Aldose reductase pathway inhibition improved vascular and C-fiber functions, allowing for pressure-induced vasodilation restoration during severe diabetic …
- Erectile dysfunction and associated risk factors in male patients with ischemic stroke: A cross-sectional study
- Diastolic heart failure: mechanisms and controversies
- Aged garlic has more potent antiglycation and antioxidant properties compared to fresh garlic extract in vitro
- Inhibition of Protein Glycation by Combined Antioxidant and Antiglycation Constituents from a Phenolic Fraction of Sage (Salvia officinalis L.)
- Neuronal cell death and regeneration in diseases associated with advanced glycation end-products accumulation
- Advanced glycation end-products: a review
- Pharmacological evaluation of novel alagebrium analogs as methylglyoxal scavengers in vitro in cardiac myocytes and in vivo in SD rats
- Heart failure with preserved ejection fraction: a clinical dilemma
- Are AGEs Implicated in Atherosclerosis?
- Nitric oxide and the regulation of large artery stiffness: from physiology to pharmacology
- RAGE: a multi-ligand receptor unveiling novel insights in health and disease
- Browsed by Tag: Oisin Biotechnologies
- Regenerative therapies for diabetic microangiopathy
- URINARY PROTEOMICS IN DIABETES AND CHRONIC RENAL DISEASE
- Collagen peptide simulated bending after applied axial deformation
- Heart failure with preserved ejection fraction: current understanding and emerging concepts
- Mechanisms of diabetic vasculopathy: an overview
- Disturbance of macro-and microcirculation: relations with pulse pressure and cardiac organ damage
- Glycation of human high density lipoprotein by methylglyoxal: effect on HDL-paraoxonase activity
- Review article New therapeutic goals–new drugs in heart failure treatment
- Stochastic non-enzymatic modification of long-lived macromolecules-A missing hallmark of aging
- Flavonoids derived from buckwheat hull can break advanced glycation end-products and improve diabetic nephropathy
- Antiamylase, Antiglucosidase, and Antiglycation Properties of Millets and Sorghum from Sri Lanka
- Glycation-induced modification of tissue-specific ECM proteins: A pathophysiological mechanism in degenerative diseases
- Causes and characteristics of diabetic cardiomyopathy
- Assessing wide pulse pressure hypertension: data beyond the guidelines
- The role of advanced glycation end products on sarcoplasmic reticulum calcium handling during diabetic cardiomyopathy
- Glycation—a sweet tempter for neuronal death
- Plasticity of kidney cells: role in kidney remodeling and scarring
- Chasing the wave. Unfashionable but important new concepts in arterial wave travel
- Cardiovascular effects of 1 year of alagebrium and endurance exercise training in healthy older individuals
- Cardiac inflammation associated with a Western diet is mediated via activation of RAGE by AGEs
- Advanced glycation end products, rage, and aging
- Age-and diabetes-induced regulation of oxidative protein modification in rat brain and peripheral tissues: Consequences of treatment with antioxidant pyridoindole
- Collagen as a double-edged sword in tumor progression
- Advanced glycation end products: a link between periodontitis and diabetes mellitus?
- Browsed by Tag: mtDNA
- Exercise training initiated in late middle age attenuates cardiac fibrosis and advanced glycation end-product accumulation in senescent rats
- The failing diabetic heart: focus on diastolic left ventricular dysfunction
- Translational applications of glucose metabolism in abdominal aortic aneurysm
- Vascular compliance in the cardiometabolic syndrome
- Association between systemic arterial stiffness and age-related macular degeneration
- Advanced Glycation–New AGE Focus for Diabetes
- Why We Age: From Healthy Aging
- Sex-specific differences in cardiac maladaptation to hypertension and arterial stiffening
- Diabetic microvascular disease: an endocrine society scientific statement
- The protective effect of aminoguanidine on erectile function in diabetic rats is not related to the timing of treatment
- Metabolic memory in the autonomic neuropathy of diabetes: implications for pathogenesis and patient care
- Advanced glycation end products and RAGE: a common thread in aging, diabetes, neurodegeneration, and inflammation
- Ventriculovascular coupling in systolic and diastolic heart failure
- Diabetic cardiomyopathy: insights into pathogenesis, diagnostic challenges, and therapeutic options
- The relationship between resistant hypertension and arterial stiffness
- Association of advanced glycation end products, evaluated by skin autofluorescence, with lifestyle habits in a general Japanese population
- Advanced glycation end products and the kidney
- LR-90 a new advanced glycation endproduct inhibitor prevents progression of diabetic nephropathy in streptozotocin-diabetic rats
- Decreasing Arterial Stiffness and/or Wave Reflections Independently of Mean Arterial Pressure: Effect of Non-antihypertensive Drugs (Part 2)
- The role of inflammaging and advanced glycation end products on paratonia in patients with dementia
- Aging: Drugs to eliminate methylglyoxal, a reactive glucose metabolite, and advanced glycation endproducts
- Inhibition of advanced glycation end-product formation and antioxidant activity by extracts and polyphenols from Scutellaria alpina L. and S. altissima L.
- Therapeutic potential of DNA-aptamers raised against AGE-RAGE axis in diabetes-related complications
- Browsed by Tag: SASP
- Pathological role of D-amino acid-containing proteins and advanced glycation end products in the development of age-related macular degeneration
- Browsed by Tag: Senescence Associated Secretory Phenotype
- Molecular mechanisms of diabetic vasculopathy
- Role of advanced glycation end products in hypertension and atherosclerosis: therapeutic implications
- Browsed by Tag: SRF
- Exercise Intolerance in Diastolic Heart Failure
- Scrutiny of cardiovascular risk factors by assessing arterial stiffness in erectile dysfunction patients
- Aortic stiffness and disease: location is key
- Aging and glycoxidant stress
- Experimental models for the study of the cellular and molecular pathophysiology of Peyronie’s disease
- Arterial stiffness: methods of measurement, physiologic determinants and prediction of cardiovascular outcomes
- The status of glycation in protein aggregation
- A CURRENT REVIEW ON THIAZOLE NUCLEUS & IT’S DERIVATIVES
- Aortic stiffness and calcification in men in a population-based international study
- Aging of myocardial collagen
- Advanced Glycation End Products Are Associated With Inflammation and Endothelial Dysfunction in HIV
- Nondiabetic glucometabolic status and progression of aortic stiffness: the Whitehall II study
- Interventions against degenerative aging
- Pulse pressure partially explains the higher incidence of cardiovascular disease associated with advanced glycation endproducts and low-grade inflammation …
- Oral L-carnitine supplementation increases trimethylamine-N-oxide but reduces markers of vascular injury in hemodialysis patients
- Evidence for the Formation of Adducts and S-(Carboxymethyl)cysteine on Reaction of α-Dicarbonyl Compounds with Thiol Groups on Amino Acids, Peptides, and …
- Slowing the aging process
- The hypertension paradox—more uncontrolled disease despite improved therapy
- Repairing extracellular aging and glycation
- Targeting the retinal microcirculation to treat diabetic sight problems
- Modification of the effect of glycemic status on aortic distensibility by age in the multi-ethnic study of atherosclerosis
- Accumulation of advanced glycation end products and chronic complications in ESRD treated by dialysis
- Interaction of metabolic and haemodynamic factors in mediating experimental diabetic nephropathy
- Anti-age antibodies and markers of oxidative stress in spontaneously hypertensive rats at different ages
- Oxidative stress and uremia
- A critical appraisal of erectile function in animal models of diabetes mellitus
- Renal nerve ablation reduces augmentation index in patients with resistant hypertension
- Non-enzymatic glycation of aminotransferases and the possibilities of its modulation
- Association of elevated apoA-I glycation and reduced HDL-associated paraoxonase1, 3 activity, and their interaction with angiographic severity of coronary …
- The stroke volume/pulse pressure ratio predicts coronary heart disease mortality in a population of elderly men
- Effect of ageing on left ventricular compliance and distensibility in healthy sedentary humans
- Aqueous extract of glucoraphanin-rich broccoli sprouts inhibits formation of advanced glycation end products and attenuates inflammatory reactions in …
- Advanced glycation endproduct-induced diabetic complications
- Future strategies for the treatment of diastolic heart failure
- Recently Published Works
- Hypertension and chronic kidney disease: respective contribution of mean and pulse pressure and arterial stiffness
- Ezrin contributes to impaired podocyte migration and adhesion caused by advanced glycation end products
- Therapeutic interventions for advanced glycation-end products and its receptor-mediated cardiovascular disease
- Erectile dysfunction as a predictor of cardiovascular events and death in diabetic patients with angiographically proven asymptomatic coronary artery disease: a …
- Update on the treatment of diabetic retinopathy
- Inhibitory Potency of C-glycosyl Flavonoids from Morus sp. on Advanced Glycation End Products
- Advanced glycation: how are we progressing to combat this web of sugar anomalies in diabetic nephropathy
- Glucose, insulin and potential strategies of vascular stiffening
- Renoprotective antioxidant effect of alagebrium in experimental diabetes
- A new perspective on therapeutic inhibition of advanced glycation in diabetic microvascular complications: common downstream endpoints achieved through …
- Abdominal aortic aneurysms and diabetes mellitus
- The year in hypertension
- Systolic hypertension in the elderly: arterial wall mechanical properties and the renin–angiotensin–aldosterone system
- DNA-aptamers raised against AGEs as a blocker of various aging-related disorders
- 24 Carotid intima–media thickness and arterial stiffness: indicators of cardiovascular risk and modifications by treatment
- Heart Failure with Preserved Ejection Fraction: Current Management and Future Strategies
- Hemodynamic effects of fenofibrate and coenzyme Q10 in type 2 diabetic subjects with left ventricular diastolic dysfunction
- Arterial stiffness
- Soluble receptor of advanced glycation end products levels are related to ischaemic aetiology and extent of coronary disease in chronic heart failure patients …
- The axis AGE-RAGE-soluble RAGE and oxidative stress in chronic kidney disease
- Arterial compliance
- Pharmacological and non-pharmacological treatment of endothelial dysfunction: relevance to diabetes
- Inhibitory activities of kaempferol against methylglyoxal formation, intermediate of advanced glycation end products
- Macrophages and diabetic nephropathy
- Ventriculovascular coupling in systolic and diastolic heart failure
- Assessing the potential of carboxylic acids as inhibitors of glycation
- Measures of arterial stiffness and wave reflection are associated with walking distance in patients with peripheral arterial disease
- Pharmaceutical medicine is an evolving discipline and research and development activity within the field is high. This section of the journal is intended to help you …
- Natriuretic peptide-guided therapy for heart failure: ready for “battle” or too “scarred” by the challenges of trial design?
- Sulforaphane reduces advanced glycation end products (AGEs)-induced inflammation in endothelial cells and rat aorta
- Health Library
- Tag: LYSOCLEAR
- Proteome wide reduction in AGE modification in streptozotocin induced diabetic mice by hydralazine mediated transglycation
- Emerging role of epigenetics and miRNA in diabetic cardiomyopathy
- Fully Atomistic Modelling of Collagen Cross-linking
- RAGE: a novel target for drug intervention in diabetic vascular disease
- Emerging role of post-translational modifications in chronic kidney disease and cardiovascular disease
- Vascular stiffening and arterial compliance: implications for systolic blood pressure
- Vascular stiffness and aging in HIV
- 21. Glycation-An imperative target in diabetes and complications
- Antioxidation and antiglycation of Fagopyrum tataricum ethanol extract
- Dynamic Changes in Myocardial Matrix and Relevance to Disease
- Relation between glycemia level and common carotid artery intima-media thickness in females
- Longitudinal analysis of low-molecular weight fluorophores in type 1 diabetes mellitus
- Glucose, Insulin and Potential
- Metabolic and biochemical stressors in diabetic cardiomyopathy
- International Research Journal of Ophthalmology
- Arterial stiffness, vascular calcification and bone metabolism in chronic kidney disease
- Advanced glycation end products (AGEs) increase renal lipid accumulation: a pathogenic factor of diabetic nephropathy (DN)
- Role of serum biomarkers in early detection of diabetic cardiomyopathy in the West Virginian population
- Effect of lecithin: cholesterol acyltransferase on the formation of cross-linked apolipoprotein AI
- Treatment of hypertensive left ventricular hypertrophy
- To AGE or not to age. The effect of physical activity and advanced glycation end-products (AGEs) on the vasculature in older individuals
- Pharmacological and non-pharmacological treatment of endothelial dysfunction: relevance to diabetes
- Cardiovascular calcifications in old age: mechanisms and clinical implications
- Arterial stiffness in chronic kidney disease: a modifiable cardiovascular risk factor?
- Deleterious Consequences of Dietary Advanced Glycation End Products on Human Health Due to Oxidative Stress and Inflammation
- Targeting Blood Pressure Lowering and the Sympathetic Nervous System
- Oxidative stress in early diabetic nephropathy: fueling the fire
- New horizons in the management of cardiovascular disease
- Elevation of serum methylglyoxal may be used as a screening marker in oral premalignant lesions.
- Circulating endothelial progenitor cells and erectile dysfunction: possibility of nutritional intervention?
- Pioglitazone attenuates vascular fibrosis in spontaneously hypertensive rats
- Antihypertensive agents and arterial stiffness: relevance to reducing cardiovascular risk in the chronic kidney disease patient
- Neurite regeneration in adult rat retinas exposed to advanced glycation end-products and regenerative effects of neurotrophin-4
- Interplay between impaired calcium regulation and insulin signaling abnormalities in diabetic cardiomyopathy
- Cardiac aging–a review
- Glycoxidation and wound healing in diabetes: an interesting relationship
- The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature
- Parkinsonism-associated protein DJ-1/Park7 is a major protein deglycase that repairs methylglyoxal-and glyoxal-glycated cysteine, arginine, and lysine residues
- The role of advanced glycation end products in vascular aging: which parameter is the most suitable as a biomarker?
- Cucumber Juice Treatment to the Decrease of Systolic and Diastolic Blood Pressure
- MRI and echocardiographic assessment of the diastolic dysfunction of normal aging: altered LV pressure decline or load?
- Novel insights in the treatment of diabetic nephropathy
- Browsed by Tag: Cellular senescence
- Ascending aortic blood pressure waveform is related to coronary atherosclerosis in hypertensive as well as in normotensive subjects
- Role of exercise and metabolism in heart failure with normal ejection fraction
- Signal transduction pathways in mouse microglia N‐11 cells activated by advanced glycation endproducts (AGEs)
- Advanced glycation end products in kidney transplant patients: a putative role in the development of chronic renal transplant dysfunction
- Diabetic myocardial disease: pathophysiology, early diagnosis and therapeutic options
- Browsed by Month: December 2017
- Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and matrix
- Pigment epithelium‑derived factor inhibits advanced glycation end product‑induced proliferation, VEGF and MMP‑9 expression in breast cancer cells via interaction …
- Diabetes and advanced glycation end products
- Role of ligands of receptor for advanced glycation end products (RAGE) in peripheral artery disease
- The heterogenic tumor microenvironment of hepatocellular carcinoma and prognostic analysis based on tumor neo-vessels, macrophages and α-SMA
- In vitro screening on amyloid beta modulation of aqueous extracts from plant seeds
- Plasma advanced glycation end products (AGEs) and NF-κB activity are independent determinants of diastolic and pulse pressure
- Commentary on some recent theses relevant to combating aging: February 2014
- Imaging of functional and structural alterations of large arteries after acute ischaemic atherothrombotic stroke or acute coronary syndromes
- Molecular effects of advanced glycation end products on cell signalling pathways, ageing and pathophysiology
- N-butanol extracts of Morinda citrifolia suppress advanced glycation end products (AGE)-induced inflammatory reactions in endothelial cells through its anti …
- Alzheimer’s disease and type 2 diabetes: different pathologies and same features
- Arterial aging
- To what extent can coronary calcification and arterial stiffness be influenced by the nephrologist?
- Renoprotective properties of angiotensin receptor blockers beyond blood pressure lowering
- Poly (adenosine 5′-diphosphate-ribose) polymerase inhibition counteracts multiple manifestations of experimental type 1 diabetic nephropathy
- Glycation, antiglycation, and deglycation: Their role in aging mechanisms and geroprotective effects (literature review)
- Advances in the non-invasive assessment of vascular dysfunction in metabolic syndrome and diabetes: focus on endothelium, carotid mechanics and renal vessels
- Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications
- Age-related vascular stiffening: causes and consequences
- Arterial stiffness and cardiovascular risk in hypertension
- Role of receptor for advanced glycation end products (RAGE) and its ligands in cancer risk
- Variants of COL3A1 are associated with the risk of stroke recurrence and prognosis in the Chinese population: a prospective study
- Metabolic dysfunction in diabetic cardiomyopathy
- Pathological Role of AGEs in Osteoporosis
- Switching dipeptidyl peptidase-4 inhibitors to tofogliflozin, a selective inhibitor of sodium-glucose cotransporter 2 improve arterial stiffness evaluated by cardio-ankle …
- New approaches to the treatment of nephropathy in diabetes
- Serum 25-hydroxyvitamin D3 is associated with advanced glycation end products (AGEs) measured as skin autofluorescence: The Rotterdam Study
- Protein carbonylation, cellular dysfunction, and disease progression
- Special clinical considerations of beta-blocker treatment
- Laboratory forum: experimental models of Peyronie’s disease. Implications for new therapies
- Agents that modulate peritoneal membrane structure and function
- Advanced glycation end-products are associated with the presence and severity of paratonia in early stage Alzheimer disease
- Vascular endothelial dysfunction in diabetic cardiomyopathy: pathogenesis and potential treatment targets
- Advanced glycation end products and their receptors in serum of patients with type 2 diabetes
- Browsed by Tag: Rejuvenation Biotechnologies
- A Receptor‐Based Bioadsorbent to Target Advanced Glycation End Products in Chronic Kidney Disease
- Compromised mechanical homeostasis in arterial aging and associated cardiovascular consequences
- Impact of non-enzymatic glycation in neurodegenerative diseases: Role of natural products in prevention
- Association of plasma pentosidine concentrations with renal function in kidney graft recipients
- Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid
- Advanced glycation end products: a molecular target for vascular complications in diabetes
- Evaluation of tissue accumulation levels of advanced glycation end products by skin autofluorescence: a novel marker of vascular complications in high-risk patients …
- Serum levels of protein-bound methylglyoxal-derived hydroimidazolone-1 are independently correlated with asymmetric dimethylarginine
- Clinical diabetic cardiomyopathy: a two-faced disease with restrictive and dilated phenotypes
- Skin autofluorescence as a marker of cardiovascular risk in children with chronic kidney disease
- Management of left ventricular diastolic heart failure: is it only blood pressure control?
- Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment
- AGE and RAGE inhibitors in the treatment of diabetic retinopathy
- Effect of diabetes and aminoguanidine therapy on renal advanced glycation end-product binding
- Paradox of circulating advanced glycation end product concentrations in patients with congestive heart failure and after heart transplantation
- Advanced glycation end products and diabetic retinopathy
- Pulse wave velocity—a useful tool for cardiovascular surveillance in pre-dialysis patients
- Arterial stiffness–A measurable vascular marker in clinical practice
- Pulse wave analysis and diabetes mellitus. A systematic review.
- A review on mechanism of inhibition of advanced glycation end products formation by plant derived polyphenolic compounds
- Non-invasive measurements of arterial function: What? When? Why should we use them?
- Cardiorenal syndrome type 4: From chronic kidney disease to cardiovascular impairment
- Phytochemicals against advanced glycation end products (AGEs) and the receptor system
- IL-1β, RAGE and FABP4: targeting the dynamic trio in metabolic inflammation and related pathologies
- Glycation and tubulointerstitial injury; in vitro and in vivo studies
- From ‘optimal’to ‘borderline’blood pressure in subjects under chronic antihypertensive therapy
- Rosuvastatin slows the development of diastolic dysfunction in calcific aortic stenosis
- Evolution and modulation of age-related medial elastocalcinosis: impact on large artery stiffness and isolated systolic hypertension
- PLC/CAMK IV–NF-κB involved in the receptor for advanced glycation end products mediated signaling pathway in human endothelial cells
- Targeting inflammation in diabetic nephropathy: a tale of hope
- Effects of vitamin D restricted diet administered during perinatal and postnatal periods on the penis of Wistar rats
- Diabetes and kidney disease
- Soluble receptor for advanced glycation end products and increased aortic stiffness in the general population
- The association of non-invasive skin autofluorescence measurements with cardiovascular and all-cause mortality in hemodialysis patients: a meta-analysis
- Novel pharmacological treatments for heart failure
- Smooth muscle cell pathophysiology and advanced glycation end products (AGEs)
- Regulation of matrix synthesis, remodeling and accumulation in glomerulosclerosis
- Selective Substitution of 31/42–OH in Rapamycin Guided by an in Situ IR Technique
- The Impact of Diabetic Renal Disease
- A tense situation: forcing tumour progression
- Novel drugs and their targets in the potential treatment of diabetic retinopathy
- Early functional and structural microvascular changes in hypertension related to aging
- Soluble receptor for advanced glycation end-products independently influences individual age-dependent increase of arterial stiffness
- Casein Hydrolysate Containing Milk-Derived Peptides Reduces Facial Pigmentation Partly by Decreasing Advanced Glycation End Products in the Skin: A …
- Diabetes mellitus-associated atherosclerosis
- Future Therapies in Diastolic Heart Failure
- Large arteries and the kidney
- Aged garlic has more potent antiglycation and antioxidant properties compared to fresh garlic extract in vitro
- Recent advances in diabetic nephropathy
- Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging
- The Effect Of Foam Rolling On Pulse Wave Velocity
- Glycation-induced protein aggregation and cellular toxicity: an insight into the disease realm of high dietary sugar intake
- A concise appraisal of lipid oxidation and lipoxidation in higher plants
- Diabetic Cardiomyopathy: Current Status
- 8th EASD/JDRF OXFORD WORKSHOP
- Current and future initiatives for vascular health management in clinical practice
- Microvessel vascular smooth muscle cells contribute to collagen type I deposition through ERK1/2 MAP kinase, αvβ3-integrin, and TGF-β1 in response to ANG II and …
- Alagebrium inhibits neointimal hyperplasia and restores distributions of wall shear stress by reducing downstream vascular resistance in obese and diabetic rats
- Association of physical fitness with skin autofluorescence-derived advanced glycation end products in children
- Breakthrough in heart failure with preserved ejection fraction: are we there yet?
- Albumin Exchange in Alzheimer’s Disease: Might CSF Be an Alternative Route to Plasma?
- Effects of adipose-derived stem cells plus insulin on erectile function in streptozotocin-induced diabetic rats
- Diabetic cardiomyopathy
- Cardiovascular biomarkers in CKD: pathophysiology and implications for clinical management of cardiac disease
- Preservation of pressure-induced cutaneous vasodilation by limiting oxidative stress in short-term diabetic mice
- Diastology E-Book: Clinical Approach to Diastolic Heart Failure
- Pyridoxamine prevents age-related aortic stiffening and vascular resistance in association with reduced collagen glycation
- Aging biology in the kidney
- Pathogenesis and pathophysiology of diabetic nephropathy
- Diastolic heart failure: progress, treatment challenges, and prevention
- Cellular therapy using microglial cells
- Hypertension, systolic blood pressure, and large arteries
- Browsed by Tag: Unity Biotechnology
- The melibiose-derived glycation product mimics a unique epitope present in human and animal tissues
- Matrix metalloproteinases are possible targets in monocrotaline-induced pulmonary hypertension: investigation of anti-remodeling effects of alagebrium and …
- High-density lipoprotein at the interface of type 2 diabetes mellitus and cardiovascular disorders
- Treatment of heart failure with normal ejection fraction: an inconvenient truth!
- Annual update 2004/2005-Treatment of cardiovascular disorders
- Diabetic nephropathy: where hemodynamics meets metabolism
- Will new antihypertensive drugs emerge? Part 1
- Can we justify goal blood pressure of< 140/90 mm Hg in most hypertensives?
- Pathological role of advanced glycation end products (AGEs) and their receptor axis in atrial fibrillation
- Methylglyoxal promotes oxidative stress and endothelial dysfunction
- The roles of protein glycation, glycoxidation, and advanced glycation end-product formation in diabetes-induced atherosclerosis
- Advanced glycation end products and cardiovascular disease
- Functional decorations: post-translational modifications and heart disease delineated by targeted proteomics
- Mechanisms, significance and treatment of vascular dysfunction in type 2 diabetes mellitus
- Pathologic role of dietary advanced glycation end products in cardiometabolic disorders, and therapeutic intervention
- Coevolution of the tumor microenvironment revealed by quantum dot-based multiplexed imaging of hepatocellular carcinoma
- Anagliptin, a dipeptidyl peptidase-4 inhibitor ameliorates arterial stiffness in association with reduction of remnant-like particle cholesterol and alanine transaminase …
- Sarcopenia in chronic kidney disease: Focus on advanced glycation end products as mediators and markers of oxidative stress
- Mimetics of hormetic agents: stress-resistance triggers
- Daily monitoring of arterial stiffness in children with end-stage renal disease
- Daily Monitoring of Arterial Stiffness in Children with End-stage Renal Disease
- Differential effects of glyoxalase 1 overexpression on diabetic atherosclerosis and renal dysfunction in streptozotocin‐treated, apolipoprotein E‐deficient mice
- Urinary peptidome may predict renal function decline in type 1 diabetes and microalbuminuria
- Clinical implications for patients with heart failure with preserved ejection fraction
- The Potential Role of Gene Editing in the Aging of Somatic cells: A Review of Literature
- Vascular complications in diabetes mellitus: the role of endothelial dysfunction
- Toxicity of protein and DNA-AGEs in neurodegenerative diseases (NDDs) with decisive approaches to stop the deadly consequences
- Mechanism for the development of bone disease in diabetes: increased oxidative stress and advanced glycation end products
- Emerging drugs and indications for cardio-metabolic disorders in people with severe mental illness
- Normalizing aberrant vasculature characteristics generated by elevated extracellular matrix stiffness
- Meta-analysis of the quantitative relation between pulse pressure and mean arterial pressure and cardiovascular risk in patients with diabetes mellitus
- Hypertension, diabetes type II, and their association: role of arterial stiffness
- Advanced glycation end-product peptides are associated with impaired renal function, but not with biochemical markers of endothelial dysfunction and inflammation …
- Renal effects of C-peptide in experimental type-1 diabetes mellitus
- Carbohydrate Directed Photoaffinity Labelling
- Role of PPAR-δ in Diabetic Cardiomyopathy
- Hypertension: Current trends and future perspectives
- Oxidation as an important factor of protein damage: Implications for Maillard reaction
- Differential cardiovascular profiles of sodium-glucose cotransporter 2 inhibitors: critical evaluation of empagliflozin
- Cellular Noise and The Aging Process
- Effects of garlic (Allium sativum) extract on the expression of receptor for advanced glycation end products and proinflammatory cytokines secretion in peripheral blood …
- Arteries and veins
- Pathophysiology of the diabetic kidney
- L-carnosine and its Derivatives as New Therapeutic Agents for the Prevention and Treatment of Vascular Complications of Diabetes
- Medical bioremediation of age-related diseases
- Salidroside ameliorates endothelial inflammation and oxidative stress by regulating the AMPK/NF-κB/NLRP3 signaling pathway in AGEs-induced HUVECs
- Development of pharmacological screening method for evaluation of effect of drug on elevated pulse pressure and arterial stiffness
- Role of changes in state of bound water and tissue stiffness in development of age-related diseases
- Diabetic Cardiomyopathy: Insights into Pathogenesis, Diagnostic Challenges, and Therapeutic Options
- Advances in Heart Failure
- Rosiglitazone inhibits angiotensin II-induced CTGF expression in vascular smooth muscle cells––Role of PPAR-γ in vascular fibrosis
- Plasma Catestatin Levels and Advanced Glycation End Products in Patients on Hemodialysis
- Trans-resveratrol mitigates type 1 diabetes-induced oxidative DNA damage and accumulation of advanced glycation end products in glomeruli and tubules of rat …
- The reality of aging viewed from the arterial wall
- Diabetic neuropathy: mechanisms to management
- Cross linkage between oxidative stresses in diabetic nephropathy: An updated review
- Clinical presentation, treatment, and prognosis of heart failure in diabetes
- SENS Foundation: Accelerating Progress Toward Biomedical Rejuvenation
- Protective role of sulphoraphane against vascular complications in diabetes
- Cell replacement in future rejuvenation therapies
- Diabetic cardiomyopathy: signaling defects and therapeutic approaches
- Advanced glycation end products: New clinical and molecular perspectives
- Hyperglycemia impairs atherosclerosis regression in mice
- Beneficial cardiac effects of caloric restriction are lost with age in a murine model of obesity
- Preventive strategies for diabetic nephropathy
- Effects of garlic (Allium sativum) extract on the expression of receptor for advanced glycation end products and proinflammatory cytokines secretion in …
- New molecular histopathologic insights into the pathogenesis of age-related macular degeneration
- Imaging in diabetic cardiomyopathy
- Natural compounds with potential antioxidant activity; in vitro study in a model of protein glycoxidation
- Rise and fall of elastic fibers from development to aging. Consequences on arterial structure-function and therapeutical perspectives
- Serum levels of growth differentiation factor 11 are independently associated with low hemoglobin values in hemodialysis patients
- Hypertrophic cardiomyopathy
- Constitutive interpretation of arterial stiffness in clinical studies: a methodological review
- High Density Lipoproteins and Diabetes
- Browsed by Tag: DNA
- Diastolic dysfunction in hypertension
- Increased central arterial stiffness after spinal cord injury: contributing factors, implications, and possible interventions
- Microvessels Vascular Smooth Muscle Cells Contribute to Collagen Type-I deposition Through ERK1/2 MAP-kinase, αvβ3-Integrin and TGFβ1 in Response to …
- Treatment with the herbal medicine, naoxintong improves the protective effect of high‑density lipoproteins on endothelial function in patients with type 2 …
- Exercise training as therapy for heart failure: current status and future directions
- Factors influencing crosslink formation in muscle tissue
- Echocardiographic Evaluation of Cardiac Function in Patients with Newly Detected Type 2 Diabetes Mellitus
- Oral administration of spa-derived green alga improves insulin resistance in overweight subjects: Mechanistic insights from fructose-fed rats
- Central artery stiffness and thoracic aortopathy
- Regulation and bioactivity of the CCN family of genes and proteins in obesity and diabetes
- Glycation and antioxidants: hand in the glove of antiglycation and natural antioxidants
- Recent advances in Raman spectroscopy of proteins for disease diagnosis
- Browsed by Tag: diseases
- Novel therapies in acute and chronic heart failure
- Associations between structural and functional changes to the kidney in diabetic humans and mice
- Calcified splenic artery
- Cardiovascular ageing in health sets the stage for cardiovascular disease
- The paraoxonase 1 (PON1), platelet-activating factor acetylohydrolase (PAF-AH) and dimethylarginine dimethylaminohydrolase (DDAH) activity in the metformin …
- Role of Amino Acids on Prevention of Nonenzymatic Glycation of Lens Proteins in Senile and Diabetic Cataract
- Potential properties of plant sprout extracts on amyloid β
- Diabetic cardiovascular disease induced by oxidative stress
- Skin aging handbook: an integrated approach to biochemistry and product development
- Present insights on cardiomyopathy in diabetic patients
- Diabetes and Pancreatic Cancer—A Dangerous Liaison Relying on Carbonyl Stress
- Investigation of circulating RAGE in patients with cardiovascular disease
- Applied healthspan engineering
- Arterial de-stiffing Drugs: Which Promising Therapeutic Agent is Useful?
- Diabetic HDL is dysfunctional in stimulating endothelial cell migration and proliferation due to down regulation of SR-BI expression
- Low glial angiotensinogen improves body habitus, diastolic function, and exercise tolerance in aging male rats
- Efficacy of sitagliptin in retarding the progression of albuminuria and assessing its safety and efficacy in patients with diabetic nephropathy
- Pacing and Diastolic Heart Failure
- Assessment of protein glycoxidation in ventricular tissues
- Diet-Derived Advanced Glycation End Products (dAGEs) Induce Proinflammatory Cytokine Expression in Cardiac and Renal Tissues of Experimental Mice: Protective …
- Age-related changes in the mechanical properties of large arteries
- Extracellular matrix
- New insights into arterial stiffening: does sex matter?
- Plant-derived agents with anti-glycation activity
- Cardiac tissue remodeling in healthy aging: the road to pathology
- Receptor for AGEs (RAGE) as mediator of NF-kB pathway activation in neuroinflammation and oxidative stress
- Assessing the functional properties of high-density lipoproteins: an emerging concept in cardiovascular research
- The clinical dilemma of heart failure with preserved ejection fraction: an update on pathophysiology and management for physicians
- Modification of the Glycemic Status on Aortic Distensibility by Age in the Multi-Ethnic Study of Atherosclerosis
- Environmental health risk perception of hydraulic fracturing in the US
- LIVIU KLEIN, MD, MS ROBERT O. BONOW, MD
- Metabolic effects of metformin in the failing heart
- Chronic heart failure in the elderly: a current medical problem
- Redox control of renal function and hypertension
- A concise appraisal of lipid oxidation and lipoxidation in higher plants
- Pathogenesis of renal microvascular complications in diabetes mellitus
- Treating Arterial Ageing in Patients with Diabetes: From Mechanisms to Effective Drugs
- Nitrite modification of extracellular matrix alters CD46 expression and VEGF release in human retinal pigment epithelium
- Developing and characterization of bioadsorbent for extracorporeal blood purification
- Biocompatibility of icodextrin
- Current therapies and emerging targets for the treatment of diabetes
- Lipoprotein glycation in diabetes mellitus
- Treatment of Heart Failure With Normal Ejection Fraction
- Alteration of nitric oxide-mediated blood flow regulation in diabetes mellitus
- Eye lens in aging and diabetes: effect of quercetin
- Dietary interventions to reduce advanced glycation endproducts (AGEs)
- Nöronal Plastisite ve Nörodejeneratif Hastalıklarda NF-κB’nin Rolü
- Alterations in circulatory function
- Twenty-five years since the discovery of endothelium-derived relaxing factor (EDRF): does a dysfunctional endothelium contribute to the development of type 2 …
- Aging and the Frontier Ahead
- The thiamine analogue and advanced glycation endproducts crosslink breaker ALT-711 does not interfere with transketolase activity
- Current and future antihypertensive drugs in post-transplant hypertension and related patents
- Preventive aspects in peripheral artery disease
- Prevention of advanced glycation end-products formation in diabetic rats through beta-cell modulation by Aegle marmelos
- Maculoplasty for age-related macular degeneration: reengineering Bruch’s membrane and the human macula
- N⁶-formylation of lysine: a pathological secondary modification of proteins
- Browsed by Tag: Aubrey de Grey
- Early detection and significance of structural cardiovascular abnormalities in patients with Type 2 diabetes mellitus
- Browsed by Tag: cancer
- New antihypertensive drugs under development
- Effects of Age and Immune Dysfunction on the Cardiac Extracellular Matrix and Diastolic Function
- AGE/RAGE signaling-mediated endoplasmic reticulum stress and future prospects in non-coding RNA therapeutics for diabetic nephropathy
- Protective effects of desacyl ghrelin on doxorubicin-induced and diabetic cardiomyopathy
- Role of methylglyoxal in the pathogenesis of hypertension
- Bone quality analysis of jaw bones in individuals with type 2 diabetes mellitus—post mortem anatomical and microstructural evaluation
- Is endothelial dysfunction the one to blame in Heart Failure with Preserved Ejection Fraction?
- Protective effect of some natural products on glucose or methylglyoxal induced glycation of superoxide dismutase
- PROTECTIVE EFFECT OF SOME NATURAL PRODUCTS ON GLUCOSE OR METHYLGLYOXAL INDUCED GLYCATION OF SUPEROXIDE DISMUTASE
- Pleiotropic consequences of metabolic stress for the major histocompatibility complex class II molecule antigen processing and presentation machinery
- Effects of phosphate binding with sevelamer carbonate on cardiovascular structure and function in patients with early chronic kidney disease
- Finite element modeling of collagen fibers in the mechanical interaction between cells and the extracellular matrix
- Methylglyoxal-induced increase in peroxynitrite and inflammation related to diabetes
- Meta-profiles of gene expression during aging: limited similarities between mouse and human and an unexpectedly decreased inflammatory signature
- Traditional, Nontraditional, and Uremia-Related Threats for Cardiovascular Disease in Chronic Kidney Disease
- Evolving insights into the pathophysiology of diabetic neuropathy: implications of malfunctioning glia and discovery of novel therapeutic targets
- Bibliography Current World Literature Vol 19 No 4 July 2004
- Stromal regulation of vessel stability by MMP14 and TGFβ
- Traditional, Nontraditional, and Uremia-Related Threats for Cardiovascular Disease in Chronic Kidney
- The efficacy of dry beans (Phaseolus vulgaris L.) for improving vascular function: exploring seed coat colour as an indicator of functionality
- The compensatory enrichment of sphingosine-1-phosphate harbored on glycated high-density lipoprotein restores endothelial protective function in type 2 …
- The Mystery of Diabetic Cardiomyopathy: From Early Concepts and Underlying Mechanisms to Novel Therapeutic Possibilities
- Stimulatory effects of non-enzymatic glycation on fibronectin matrix assembly
- The RAGE Axis
- Aging and Cardiovascular Risk
- Regulation of Focal Adhesion Dynamics by a Kinesin Motor Kid/KIF22/Kinesin-10
- Myocardial contraction fraction, diabetes and heart failure: The multi ethnic study of atherosclerosis
- Positions held
- Vascular function and structure in the rat aorta
- Regulation of aging in yeast by glycation inhibitors
- Atomic Force Microscopy-based essay for biomedical applications
- The impact of the diabetic state on gingival tissues: The role of tetracyclines in disease management
- Immnochemical Studies on Glycated Human Serum Albumin: Role of Aminoguanidine and Thymoquinone in the Reduction of Glycation Products in Diabetes …
- Perturbation of cellular and vascular function by hyperglycaemia and hyperlipidaemia and their role in cardiovascular disease
- Psychosocial and Oxidative Stress and Health of Adults
- Comprehensive nanorobotic control of human morbidity and aging
- Relationship between a trial fibrillation and hypertension in rats
- Antioxidant and Antiglycation Properties of Fifteen Cultivated and Wild Vigna Species
- Vascular Stem and Progenitor Cells in Diabetic Complications
- Rôle du système rénine-angiotensine intrarénal dans l’hypertension et les dommages rénaux chez les souris transgéniques diabétiques
- Renal immunology and pathology
- Arterial stiffness and subclinical atherosclerosis in elderly participants from the Cardiovascular Health Study
- Emerging drugs for diabetic nephropathy
