CENTENARIANS
January 18, 2020INFLAMMATION & DEPRESSION
January 20, 2020- Genistein
- Genistein, a specific inhibitor of tyrosine-specific protein kinases.
- Neonatal Genistein chemoprevents mammary cancer
- Genistein, a dietary-derived inhibitor of in vitro angiogenesis
- Genistein suppresses mammary cancer in rats
- Antioxidant and antipromotional effects of the soybean isoflavone Genistein
- Genistein arrests cell cycle progression at G2-M
- Molecular effects of Genistein on estrogen receptor mediated pathways
- Uterine adenocarcinoma in mice treated neonatally with Genistein
- Mechanisms of cancer chemoprevention by soy isoflavone Genistein
- Daidzein and Genistein content of fruits and nuts
- Quantification of Genistein and genistin in soybeans and soybean products
- Protection against breast cancer with Genistein: a component of soy
- [30] Use and specificity of Genistein as inhibitor of protein-tyrosine kinases
- Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells.
- Enhancement of experimental colon cancer by Genistein
- Genistein as an anti-inflammatory agent
- Genistein inhibits protein histidine kinase.
- Genistein alters methylation patterns in mice
- Effect of Genistein on in vitro and in vivo models of cancer
- Genistein exerts multiple suppressive effects on human breast carcinoma cells
- Inhibitory effects of the tyrosine kinase inhibitor Genistein on mammalian DNA topoisomerase II
- The antioxidant activity of Genistein in vitro
- Genistein inhibits NF-kB activation in prostate cancer cells
- Cancer chemoprevention agent development strategies for Genistein
- Daidzein is a more bioavailable soymilk isoflavone than is Genistein in adult women
- Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis
- The soy isoflavone Genistein decreases adipose deposition in mice
- Effect of dietary Genistein on antioxidant enzyme activities in SENCAR mice
- Evaluation of the biochemical targets of Genistein in tumor cells
- The phytoestrogen Genistein reduces bone loss in short-term ovariectomized rats
- Genistein, daidzein, and their. beta.-glycoside conjugates: antitumor isoflavones in soybean foods from American and Asian diets
- Intestinal uptake and biliary excretion of the isoflavone Genistein in rats
- Metabolism of daidzein and Genistein by intestinal bacteria
- Genistein chemoprevention: timing and mechanisms of action in murine mammary and prostate
- Prepubertal Genistein exposure suppresses mammary cancer and enhances gland differentiation in rats
- Genistin (an isoflavone glucoside) and its aglucone, Genistein, from soybeans
- Daidzein and Genistein content of cereals
- Genistein: does it prevent or promote breast cancer?
- Prepubertal exposure to zearalenone or Genistein reduces mammary tumorigenesis
- Isoflavone Genistein: photoprotection and clinical implications in dermatology
- Direct action of Genistein on CFTR
- Biochemical targets of the isoflavone Genistein in tumor cell lines
- Radical scavenging properties of Genistein
- Dietary Genistein: perinatal mammary cancer prevention, bioavailability and toxicity testing in the rat.
- Induction of apoptosis in breast cancer cells MDA-MB-231 by Genistein
- Genistein treatment protects mice from ionizing radiation injury
- Estrogenic and antiproliferative properties of Genistein and other flavonoids in human breast cancer cells in vitro
- Absorption and excretion of the soy isoflavone Genistein in rats
- Inhibition of tumor Promoter‐induced hydrogen peroxide formation in vitro and in vivo by Genistein
- Genistein, a soy isoflavone, is a potent α‐glucosidase inhibitor
- Genistein inhibition of the growth of human breast cancer cells: independence from estrogen receptors and the multi-drug resistance gene
- The phytoestrogen Genistein induces thymic and immune changes: a human health concern?
- Effect of Genistein on topoisomerase activity and on the growth of [Val 12] Ha-ras-transformed NIH 3T3 cells
- Effects of soy phytoestrogens Genistein and daidzein on breast cancer growth
- Biphasic effects of Genistein on bone tissue in the ovariectomized, lactating rat model
- Extraction and quantification of daidzein and Genistein in food
- Genistein potentiates wild-type and delta F508-CFTR channel activity
- Genistein as an inducer of tumor cell differentiation: possible mechanisms of action
- Plasma and urinary kinetics of the isoflavones daidzein and Genistein after a single soy meal in humans
- Induction of mammalian topoisomerase II dependent DNA cleavage by nonintercalative flavonoids, Genistein and orobol
- Biological properties of Genistein. A review of in vitro and in vivo data
- Mass spectrometric determination of Genistein tissue distribution in diet-exposed Sprague-Dawley rats
- Peroxisome proliferator-activated receptor γ (PPARγ) as a molecular target for the soy phytoestrogen Genistein
- Difference in effective dosage of Genistein on bone and uterus in ovariectomized mice
- Daidzein is more efficient than Genistein in preventing ovariectomy-induced bone loss in rats
- Genistein affects lipogenesis and lipolysis in isolated rat adipocytes
- Biotherapy of B-cell precursor leukemia by targeting Genistein to CD19-associated tyrosine kinases
- Anabolic effect of Genistein in osteoblastic MC3T3-E1 cells.
- Daidzein and Genistein but not their glucosides are absorbed from the rat stomach
- Inhibitory effect of Genistein on bone resorption in tissue culture
- Dietary Genistein exerts estrogenic effects upon the uterus, mammary gland and the hypothalamic/pituitary axis in rats
- Rationale for the use of Genistein‐containing soy matrices in chemoprevention trials for breast and prostate cancer
- Daidzein and Genistein concentrations in human milk after soy consumption.
- Genistein and biochanin A inhibit the growth of human prostate cancer cells but not epidermal growth factor receptor tyrosine autophosphorylation
- Genistein and gut inflammation: role of nitric oxide
- Estrogenic effects of Genistein on the growth of estrogen receptor-positive human breast cancer (MCF-7) cells in vitro and in vivo
- The effect of prenatal exposure to the phytoestrogen Genistein on sexual differentiation in rats
- cAMP-independent activation of CFTR Cl channels by the tyrosine kinase inhibitor Genistein
- Reproductive effects in male and female rats of neonatal exposure to Genistein
- Genistein exerts estrogen-like effects in male mouse reproductive tract
- Time-resolved fluoroimmunoassay of plasma daidzein and Genistein
- Inhibition of nuclear factor κB activation in PC3 cells by Genistein is mediated via Akt signaling pathway
- Production of the isoflavones Genistein and daidzein in non-legume dicot and monocot tissues
- Genistein in the diet reduces the incidence of poorly differentiated prostatic adenocarcinoma in transgenic mice (TRAMP)
- Genistein induces apoptosis in immature human thymocytes by inhibiting topoisomerase-II
- Exposure to Genistein during gestation and lactation demasculinizes the reproductive system in rats
- Inhibition of UV light-and Fenton Reaction-induced oxidative DNA damage by the soybcan isoflavone Genistein
- Metabolites of daidzein and Genistein and their biological activities
- Genistein is neuroprotective in murine models of familial amyotrophic lateral sclerosis and stroke
- p53-independent apoptosis induced by Genistein in lung cancer cells
- Inhibition of drug transport by Genistein in multidrug-resistant cells expressing P-glycoprotein
- Growth-inhibitory effects of the natural phyto-oestrogen Genistein in MCF-7 human breast cancer cells
- Genistein, a protein tyrosine kinase inhibitor, inhibits thromboxane A2-mediated human platelet responses
- Genistein inhibits proliferation and in vitro invasive potential of human prostatic cancer cell lines.
- Selective effects of Genistein, a soybean isoflavone, on B-lymphopoiesis and bone loss caused by estrogen deficiency
- Gene expression profiles of Genistein-treated PC3 prostate cancer cells
- Maternal exposure to Genistein during pregnancy increases carcinogen-induced mammary tumorigenesis in female rat offspring.
- Phytoestrogen Genistein stimulates the production of osteoprotegerin by human trabecular osteoblasts
- Induction of differentiation and DNA strand breakage in human HL-60 and K-562 leukemia cells by Genistein
- The inhibitory effect of curcumin, Genistein, quercetin and cisplatin on the growth of oral cancer cells in vitro.
- Mechanisms of action in NIH-3T3 cells of Genistein, an inhibitor of EGF receptor tyrosine kinase activity
- Soy diets containing varying amounts of Genistein stimulate growth of estrogen-dependent (MCF-7) tumors in a dose-dependent manner
- Mechanisms of action of the soy isoflavone Genistein: emerging role for its effects via transforming growth factor beta signaling pathways
- The two phyto-oestrogens Genistein and quercetin exert different effects on oestrogen receptor function
- The natural tyrosine kinase inhibitor Genistein produces cell cycle arrest and apoptosis in Jurkat T-leukemia cells
- Genistein, the dietary-derived angiogenesis inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL
- Anaerobic C-ring cleavage of Genistein and daidzein by Eubacterium ramulus
- Dietary Genistein down-regulates androgen and estrogen receptor expression in the rat prostate
- Alternate stimulation of apical CFTR by Genistein in epithelia
- Genistein supplementation and estrogen replacement therapy improve endothelial dysfunction induced by ovariectomy in rats
- Effects of Genistein and hormone‐replacement therapy on bone loss in early postmenopausal women: a randomized double‐blind placebo‐controlled study
- Effects of dietary Genistein exposure during development on male and female CD (Sprague-Dawley) rats
- Genistein‐induced upregulation of p21 WAF1 , downregulation of cyclin B, and induction of apoptosis in prostate cancer cells
- Inhibitory actions of Genistein in human breast cancer (MCF-7) cells
- Dietary Genistein inactivates rat thyroid peroxidase in vivo without an apparent hypothyroid effect
- Genistein-induced changes in lipid metabolism of ovariectomized rats
- Inactivation of NF-κB by Genistein is mediated via Akt signaling pathway in breast cancer cells
- The isoflavone Genistein inhibits copper and peroxyl radical mediated low density lipoprotein oxidation in vitro
- Effect of Genistein on endothelial function in postmenopausal women: a randomized, double-blind, controlled study
- Genistein inhibits the growth of human‐patient BPH and prostate cancer in histoculture
- Comparing the pharmacokinetics of daidzein and Genistein with the use of 13C-labeled tracers in premenopausal women
- Genistein blocks breast cancer cells in the G2M phase of the cell cycle
- Dietary Genistein suppresses chemically induced prostate cancer in Lobund–Wistar rats
- Effects of Genistein exposure on sexually dimorphic behaviors in rats
- 761. The chemistry of subterranean clover. Part I. Isolation of formononetin and Genistein
- Genistein induces apoptosis and topoisomerase II-mediated DNA breakage in colon cancer cells
- Dietary genistin stimulates growth of estrogen-dependent breast cancer tumors similar to that observed with Genistein
- Radioimmunoassay of free Genistein in human serum
- Estrogen receptor β mRNA in colon cancer cells: growth effects of estrogen and Genistein
- Oxidative in vitro metabolism of the soy phytoestrogens daidzein and Genistein
- Genistein studies in rats: potential for breast cancer prevention and reproductive and developmental toxicity
- Urinary and biliary metabolites of Genistein in rats
- cAMP and Genistein stimulate HCO3-conductance through CFTR in human airway epithelia
- Dietary flavonoids, quercetin, luteolin and Genistein, reduce oxidative DNA damage and lipid peroxidation and quench free radicals
- Oxidative metabolism of the soy isoflavones daidzein and Genistein in humans in vitro and in vivo
- Genistein induces apoptosis of RPE-J cells by opening mitochondrial PTP
- Absorption and metabolism of Genistein in isolated rat small intestine
- Normalization of retinal vascular permeability in experimental diabetes with Genistein
- Daidzein and Genistein glucuronides in vitro are weakly estrogenic and activate human natural killer cells at nutritionally relevant concentrations
- Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity
- Transport of Genistein-7-glucoside by human intestinal CACO-2 cells: potential role for MRP2.
- Daidzein conjugates are more bioavailable than Genistein conjugates in rats
- Cardioprotection by the phytoestrogen Genistein in experimental myocardial ischaemia‐reperfusion injury
- Genistein potentiates the radiation effect on prostate carcinoma cells
- Cytotoxic activity of epidermal growth factor-Genistein against breast cancer cells.
- An in vitro and in vivo study of antitumor effects of Genistein on hormone refractory prostate cancer.
- Identification of the isoflavonoid Genistein in bleached kraft mill effluent
- Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells
- The effect of the phytoestrogen Genistein on plasma nitric oxide concentrations, endothelin-1 levels and endothelium dependent vasodilation in postmenopausal …
- Topical N-acetyl cysteine and Genistein prevent ultraviolet-light-induced signaling that leads to photoaging in human skin in vivo
- Genistein alters the ontogeny of mammary gland development and protects against chemically-induced mammary cancer in rats
- Genistein action in the prepubertal mammary gland in a chemoprevention model
- The phytoestrogen Genistein suppresses cell-mediated immunity in mice
- The effects of the phytoestrogen Genistein on the postnatal development of the rat
- Genistein prevents nuclear factor-kappa B activation and acute lung injury induced by lipopolysaccharide
- Galectin-3 mediates Genistein-induced G2/M arrest and inhibits apoptosis
- Genistein elicits pleiotropic molecular effects on head and neck cancer cells
- Thermal stability of Genistein and daidzein and its effect on their antioxidant activity
- Mechanism for the suppression of the mammalian stress response by Genistein, an anticancer phytoestrogen from soy
- Quantification of soy isoflavones, Genistein and daidzein, and conjugates in rat blood using LC/ES-MS
- Inhibition of prostate specific antigen expression by Genistein in prostate cancer cells.
- Inhibitory effect of Genistein on osteoclast-like cell formation in mouse marrow cultures
- Physiological concentrations of dietary Genistein dose-dependently stimulate growth of estrogen-dependent human breast cancer (MCF-7) tumors implanted in …
- Defective function of the cystic fibrosis-causing missense mutation G551D is recovered by Genistein
- Developmental effects of dietary phytoestrogens in Sprague-Dawley rats and interactions of Genistein and daidzein with rat estrogen receptors alpha and beta in vitro.
- Inhibition of the proteasome activity, a novel mechanism associated with the tumor cell apoptosis-inducing ability of Genistein
- The phytoestrogen Genistein produces acute nitric oxide–dependent dilation of human forearm vasculature with similar potency to 17β-estradiol
- Anabolic effect of Genistein and genistin on bone metabolism in the femoral-metaphyseal tissues of elderly rats: The Genistein effect is enhanced by zinc
- Isoflavone Genistein inhibits the initiation and promotion of two-stage skin carcinogenesis in mice.
- A comparative survey of leguminous plants as sources of the isoflavones, Genistein and daidzein: implications for human nutrition and health
- Genistein, a soy isoflavone, induces glutathione peroxidase in the human prostate cancer cell lines LNCaP and PC‐3
- Antiinflammatory effects of Genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma
- Genistein induces maturation of cultured human breast cancer cells and prevents tumor growth in nude mice
- Dietary Genistein negates the inhibitory effect of tamoxifen on growth of estrogen-dependent human breast cancer (MCF-7) cells implanted in athymic mice
- Genistein inhibits both constitutive and EGF-stimulated invasion in ER-negative human breast carcinoma cell lines.
- Prevention of precancerous colonic lesions in rats by soy flakes, soy flour, Genistein, and calcium
- Synergistic action of quercetin and Genistein in human ovarian carcinoma cells
- Genistein protects primary cortical neurons from iron-induced lipid peroxidation
- Genistein‐induced G2‐m arrest, P21WAF1 upregulation, and apoptosis in a non‐small‐cell lung cancer cell line
- Urinary pharmacokinetics of the glucuronide and sulfate conjugates of Genistein and daidzein
- Genistein is a natural inhibitor of hexose and dehydroascorbic acid transport through the glucose transporter, GLUT1
- Effects of the isoflavones Genistein and equol on the gonadal development of Japanese medaka Oryzias latipes.
- Different effects of Genistein and resveratrol on oxidative DNA damage in vitro
- Inhbition of invasion of murine mammary carcinoma cells by the tyrosine kinase inhibitor Genistein
- Endothelium-dependent relaxation of rat aorta and main pulmonary artery by the phytoestrogens Genistein and daidzein
- Placental transfer of the soy isoflavone Genistein following dietary and gavage administration to Sprague Dawley rats
- Effects of Genistein on the endometrium: ultrasonographic evaluation
- Soya phytoestrogens, Genistein and daidzein, decrease apolipoprotein B secretion from HepG2 cells through multiple mechanisms
- … dilution gas chromatographic-mass spectrometric method for the determination of lignans and isoflavonoids in human urine, including identification of Genistein
- Metabolism of the isoflavones Genistein and biochanin A in human breast cancer cell lines
- Genistein affects ERβ-but not ERα-dependent gene expression in the hypothalamus
- Induction of apoptosis and inhibition of c-erbB-2 in MDA-MB-435 cells by Genistein.
- Modulation of CFTR chloride channels by calyculin A and Genistein
- Changes in the profile of Genistein, daidzein, and their conjugates during thermal processing of tofu
- Actions of Genistein on cystic fibrosis transmembrane conductance regulator channel gating: evidence for two binding sites with opposite effects
- The interaction in the immature mouse of potent oestrogens with coumestrol, Genistein and other utero-vaginotrophic compounds of low potency
- Genistein in the control of breast cancer cell growth: insights into the mechanism of action in vitro
- 17β-Estradiol and the phytoestrogen Genistein attenuate neuronal apoptosis induced by the endoplasmic reticulum calcium-ATPase inhibitor thapsigargin
- Genistein, a component of soy, inhibits the expression of the EGF and ErbB2/Neu receptors in the rat dorsolateral prostate
- Genistein activates CFTR Cl-channels via a tyrosine kinase-and protein phosphatase-independent mechanism
- Forage estrogens, detection of daizein, formononetin, Genistein, and biochanin a in forages
- The plant isoflavenoid Genistein activates p53 and Chk2 in an ATM-dependent manner
- Pharmacokinetics of the glucuronide and sulfate conjugates of Genistein and daidzein in men and women after consumption of a soy beverage
- Genistein prevents bone resorption diseases by inhibiting bone resorption and stimulating bone formation
- Urinary disposition of the soybean isoflavones daidzein, Genistein and glycitein differs among humans with moderate fecal isoflavone degradation activity
- Suppressive effect of Genistein on rat bone osteoclasts: apoptosis is induced through Ca2+ signaling
- Genistein inhibits growth of estrogen-independent human breast cancer cells in culture but not in athymic mice
- Low‐dose Genistein induces cyclin‐dependent kinase inhibitors and G1 cell‐cycle arrest in human prostate cancer cells
- Anabolic effect of daidzein on cortical bone in tissue culture: comparison with Genistein effect
- Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics
- Genistein modulates immune responses and increases host resistance to B16F10 tumor in adult female B6C3F1 mice
- Genistein-induced cell differentiation and protein-linked DNA strand breakage in human melanoma cells
- p53‐independent induction of p21 (WAF1/CIP1), reduction of cyclin B1 and G2/M arrest by the isoflavone Genistein in human prostate carcinoma cells
- Oestrogenic activity of subterranean clover. 1. The oestrogenic activity of Genistein
- Genistein administration decreases serum corticosterone and testosterone levels in rats
- Pharmacokinetics of [14C] Genistein in the rat: gender-related differences, potential mechanisms of biological action, and implications for human health
- Reactions of Genistein with alkylperoxyl radicals
- The tyrosine kinase inhibitor Genistein directly inhibits GABAA receptors
- Preincubation of Bradyrhizobium japonicum with Genistein accelerates nodule development of soybean at suboptimal root zone temperatures
- Metabolism of Genistein by rat and human cytochrome P450s
- Phytoestrogens and carcinogenesis—differential effects of Genistein in experimental models of normal and malignant rat endometrium
- The phytoestrogens coumoestrol and Genistein induce structural chromosomal aberrations in cultured human peripheral blood lymphocytes
- Genistein is an effective stimulator of sex hormone-binding globulin production in hepatocarcinoma human liver cancer cells and suppresses proliferation of these …
- Suppressive effect of Genistein on rat bone osteoclasts: involvement of protein kinase inhibition and protein tyrosine phosphatase activation.
- Effects of Genistein on expression of bone markers during MC3T3-E1 osteoblastic cell differentiation
- Maternal Genistein exposure mimics the effects of estrogen on mammary gland development in female mouse offspring.
- Phytoestrogen Genistein acts as an estrogen agonist on human osteoblastic cells through estrogen receptors α and β
- Modulation of liver canalicular transport processes by the tyrosine‐kinase inhibitor Genistein: Implications of Genistein metabolism in the rat
- Biotransformation of Genistein in the rat: elucidation of metabolite structure by product ion mass fragmentologyn
- Inhibition of ultraviolet light-induced oxidative events in the skin and internal organs of hairless mice by isoflavone Genistein
- Effects of Genistein on the growth and cell cycle progression of normal human lymphocytes and human leukemic MOLT-4 and HL-60 cells
- Absolute bioavailability of [14C] Genistein in the rat; plasma pharmacokinetics of parent compound, Genistein glucuronide and total radioactivity
- Expression of prostate‐specific antigen is transcriptionally regulated by Genistein in prostate cancer cells
- Genistein differentially inhibits postreceptor effects of insulin in rat adipocytes without inhibiting the insulin receptor kinase.
- Genistein-induced cell cycle arrest and apoptosis in a head and neck squamous cell carcinoma cell line
- Curcumin and Genistein, plant natural products, show synergistic inhibitory effects on the growth of human breast cancer MCF-7 cells induced by estrogenic pesticides
- Cooperative effects of exercise training and Genistein administration on bone mass in ovariectomized mice
- Transcriptional inhibition of CYP24 by Genistein
- Neonatal exposure to Genistein induces estrogen receptor (ER) α expression and multioocyte follicles in the maturing mouse ovary: evidence for ERβ-mediated and …
- Differences between human breast cell lines in susceptibility towards growth inhibition by Genistein
- Inhibition of PhIP mutagenicity by caffeine, lycopene, daidzein, and Genistein
- Down-regulation of invasion and angiogenesis-related genes identified by cDNA microarray analysis of PC3 prostate cancer cells treated with Genistein
- Suppressive effects of Genistein on oxidative stress and NFκB activation in RAW 264.7 macrophages
- Pharmacokinetic analysis in serum of Genistein administered subcutaneously to neonatal mice
- Enrichment of Genistein in Soy Protein Concentrate with b‐glucosidase
- Gene expression profile induced by 17α-ethynyl estradiol, bisphenol A, and Genistein in the developing female reproductive system of the rat
- Genistein inhibits proliferation similarly in estrogen receptor‐positive and negative human breast carcinoma cell lines characterized by P21WAF1/CIP1 induction, G2 …
- Direct block of voltage-sensitive sodium channels by Genistein, a tyrosine kinase inhibitor
- Effects of Genistein, a tyrosine kinase inhibitor, on platelet functions: Genistein attenuates thrombin-induced Ca2+ mobilization in human platelets by affecting …
- Effects of neonatal treatment with phytoestrogens, Genistein and daidzein, on sex difference in female rat brain function: estrous cycle and lordosis
- Genistein augments cyclic adenosine 3′ 5′-monophosphate (cAMP) accumulation and insulin release in MIN6 cells
- In vitro Metabolism of Genistein and Tangeretin by Human and Murine Cytochrome P450s
- Genistein and vitamin D synergistically inhibit human prostatic epithelial cell growth
- Nonsteroidal anti‐inflammatory drug‐activated gene (NAG‐1) is induced by Genistein through the expression of p53 in colorectal cancer cells
- Reproductive sequelae in female rats after in utero and neonatal exposure to the phytoestrogen Genistein
- Calcium-sensitive potassium channel inhibitors antagonize Genistein-and daidzein-induced arterial relaxation in vitro
- Dietary Genistein increased DMBA-induced mammary adenocarcinoma in wild-type, but not ERαKO, mice
- Metabolism of the soy isoflavones daidzein, Genistein and glycitein in human subjects.: Identification of new metabolites having an intact isoflavonoid skeleton
- Genistein selectively inhibits platelet-derived growth factor-stimulated versican biosynthesis in monkey arterial smooth muscle cells
- Genistein-induced G2/M arrest is associated with the inhibition of cyclin B1 and the induction of p21 in human breast carcinoma cells.
- Antiangiogenic and antitumour effects in vivo of Genistein applied alone or combined with cyclophosphamide.
- Thrombin-induced human platelet aggregation is inhibited by protein-tyrosine kinase inhibitors, ST638 and Genistein
- Genistein, a soybean isoflavone, affects bone marrow lymphopoiesis and prevents bone loss in castrated male mice
- The tyrosine kinase inhibitors methyl 2, 5-dihydroxycinnamate and Genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets
- Genistein sensitizes diffuse large cell lymphoma to CHOP (cyclophosphamide, doxorubicin, vincristine, prednisone) chemotherapy
- Effects of Genistein and structurally related phytoestrogens on cell cycle kinetics and apoptosis in MDA-MB-468 human breast cancer cells.
- Purified phytoestrogens in postmenopausal bone health: is there a role for Genistein?
- Genistein inactivates bcl-2, delays the G2/M phase of the cell cycle, and induces apoptosis of human breast adenocarcinoma MCF-7 cells
- Genistein appears to prevent early postmenopausal bone loss as effectively as hormone replacement therapy
- H2O2and Genistein Differentially Modulate Protein Tyrosine Phosphorylation, Endothelial Morphology, and Monolayer Barrier Function
- Effects of Genistein and synergistic action in combination with eicosapentaenoic acid on the growth of breast cancer cell lines
- Phytoestrogens alter adrenocortical function: Genistein and daidzein suppress glucocorticoid and stimulate androgen production by cultured adrenal cortical cells
- Genistein induces p21Cip1/WAF1expression and blocks the G1 to S phase transition in mouse fibroblast and melanoma cells
- Lack of significant genotoxicity of purified soy isoflavones (Genistein, daidzein, and glycitein) in 20 patients with prostate cancer
- Effect of Genistein, a tyrosine kinase inhibitor, on U46619-induced phosphoinositide phosphorylation in human platelets
- Genistein directly inhibits L-type calcium currents but potentiates cAMP-dependent chloride currents in cardiomyocytes
- Potent inhibition of breast cancer cell lines by the isoflavonoid kievitone: comparison with Genistein
- Genistein-mediated attenuation of tamoxifen-induced antagonism from estrogen receptor-regulated genes
- Altered kinetics and extent of urinary daidzein and Genistein excretion in women during chronic soya exposure
- Oestrogenic potencies of Zeranol, oestradiol, diethylstilboestrol, Bisphenol-A and Genistein: implications for exposure assessment of potential endocrine disrupters
- Sex steroid receptor regulation by Genistein in the prepubertal rat uterus
- Pharmacologic, but not dietary, Genistein supports endometriosis in a rat model
- Daily intake and urinary excretion of Genistein and daidzein by infants fed soy-or dairy-based infant formulas
- Plasma pharmacokinetics of Genistein in mice
- p53, mutations, and apoptosis in Genistein-exposed human lymphoblastoid cells
- Induction of in vitro differentiation of mouse erythroleukemia cells by Genistein, an inhibitor of tyrosine protein kinases
- The effect of dietary soy Genistein on pig growth and viral replication during a viral challenge
- In vivo toxicity, pharmacokinetics, and anticancer activity of Genistein linked to recombinant human epidermal growth factor.
- The role of metabolism in mammary epithelial cell growth inhibition by the isoflavones Genistein and biochanin A
- Genistein prevents the glucose autoxidation mediated atherogenic modification of low density lipoprotein
- Genistein and tyrphostin 47 stimulate CFTR-mediated Cl-secretion in T84 cell monolayers
- The effect of neonatal exposure to diethylstilbestrol, Genistein, and zearalenone on pituitary responsiveness and sexually dimorphic nucleus volume in the castrated …
- Competitive inhibition by Genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells
- Genistein inhibits vitamin D hydroxylases CYP24 and CYP27B1 expression in prostate cells
- A common mechanism for cystic fibrosis transmembrane conductance regulator protein activation by Genistein and benzimidazolone analogs
- ADP-and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors Genistein and methyl-2, 5 …
- Synergistic inhibitory effects of Genistein and tamoxifen on human dysplastic and malignant epithelial breast cells in vitro
- Genistein, a tyrosine kinase inhibitor, blocks the “second window of protection” 48 h after ischemic preconditioning in the rabbit
- Interaction of Genistein with the mitochondrial electron transport chain results in opening of the membrane transition pore
- Stimulatory effect of Genistein and daidzein on protein synthesis in osteoblastic MC3T3-E1 cells: activation of aminoacyl-tRNA synthetase
- Altered time course of urinary daidzein and Genistein excretion during chronic soya diet in healthy male subjects
- Genistein-stimulated adherence of prostate cancer cells is associated with the binding of focal adhesion kinase to beta-l-integrin
- Suppressive effects of Genistein dosage and resistance exercise on bone loss in ovariectomized rats
- Differential sensitivity of normal and malignant breast epithelial cells to Genistein is partly mediated by p21WAF1
- Activation of CFTR by Genistein in human airway epithelial cell lines
- Characterization of the estrogenic response to Genistein in Japanese medaka (Oryzias latipes)
- CFTR chloride channel activation by Genistein: the role of serine/threonine protein phosphatases
- Multiple effects and stimulation of insulin secretion by the tyrosine kinase inhibitor Genistein in normal mouse islets
- Characterization of the elicitor-induced biosynthesis and secretion of Genistein from roots of Lupinus luteus L
- Genistein activates apolipoprotein AI gene expression in the human hepatoma cell line Hep G2
- The antifertility activity of isoflavones related to Genistein
- Genistein inhibits CCAAT/enhancer-binding protein β (C/EBPβ) activity and 3T3-L1 adipogenesis by increasing C/EBP homologous protein expression
- Genistein induced molecular changes in a squamous cell carcinoma of the head and neck cell line.
- Inhibition of ultraviolet B (UVB)-induced c-fos and c-jun expression in vivo by a tyrosine kinase inhibitor Genistein.
- Microarray profiling of gene expression patterns in bladder tumor cells treated with Genistein
- Soy isoflavone Genistein modulates cell cycle progression and induces apoptosis in HER-2/neu oncogene expressing human breast epithelial cells
- A soy protein isolate rich in Genistein and daidzein and its effects on plasma isoflavone concentrations, platelet aggregation, blood lipids and fatty acid composition of …
- Genistein: a potent natural antiandrogen
- Genistein inhibits tamoxifen effects on cell proliferation and cell cycle arrect in T47D breast cancer cells/Discussion
- Effect of isoflayones Genistein and daidzein in the inhibition of lung metastasis in mice induced by B16F‐10 melanoma cells
- Genistein inhibits constitutive and inducible NFκB activation and decreases IL-8 production by human cystic fibrosis bronchial gland cells
- Inoculation of soybean (Glycine max. (L.) Merr.) with Genistein-preincubated Bradyrhizobium japonicum or Genistein directly applied into soil increases soybean …
- Evidence that Genistein, a protein-tyrosine kinase inhibitor, inhibits CD28 monoclonal-antibody-stimulated human T cell proliferation.
- Genistein inhibits tumour cell growth in vitro but enhances mitochondrial reduction of tetrazolium salts: a further pitfall in the use of the MTT assay for evaluating cell …
- Pleotropic effects of Genistein on MCF-7 breast cancer cells
- Genistein, daidzein and glycitein inhibit growth and DNA synthesis of aortic smooth muscle cells from stroke-prone spontaneously hypertensive rats
- Soybean isoflavones, Genistein and genistin, inhibit rat myoblast proliferation, fusion and myotube protein synthesis
- Inhibition of L-type calcium current in rat ventricular cells by the tyrosine kinase inhibitor, Genistein and its inactive analog, daidzein
- Effect of dietary soy protein and Genistein on disease progression in mice with polycystic kidney disease
- Serum levels and metabolic clearance of the isoflavones Genistein and daidzein in hemodialysis patients
- Interaction of Genistein with oestradiol in the reproductive tract of the ovariectomized mouse
- Increased induction of aberrant crypt foci by 1, 2-dimethylhydrazine in rats fed diets containing purified Genistein or Genistein-rich soya protein
- High-performance liquid chromatographic assay for Genistein in biological fluids
- Identification of CYP1A2 as the main isoform for the phase I hydroxylated metabolism of Genistein and a prodrug converting enzyme of methylated isoflavones
- Detrimental effect of cancer preventive phytochemicals silymarin, Genistein and epigallocatechin 3‐gallate on epigenetic events in human prostate carcinoma DU145 …
- The inhibitory effect of Genistein on the growth and metastasis of a transplantable rat accessory sex gland carcinoma
- Hypoxia induces transcription of the plasminogen activator inhibitor-1 gene through Genistein-sensitive tyrosine kinase pathways in vascular endothelial cells
- Effects of the tyrosine-kinase inhibitor Genistein on DNA synthesis and phospholipid-derived second messenger generation in mouse 10T1/2 fibroblasts and rat liver …
- Modulation of Ca2+ sensitivity in smooth muscle by Genistein and protein tyrosine phosphorylation
- Neuronal apoptosis resulting from high doses of the isoflavone Genistein: role for calcium and p42/44 mitogen-activated protein kinase
- Inhibition of UV irradiation–induced oxidative stress and apoptotic biochemical changes in human epidermal carcinoma A431 cells by Genistein
- Platelet-activating factor stimulation of tyrosine kinase and its relationship to phospholipase C in rabbit platelets: studies with Genistein and monoclonal antibody …
- Synthesis and labeling of isoflavone phytoestrogens, including daidzein and Genistein
- The tyrosine kinase inhibitor, Genistein, prevents α-adrenergic-induced cardiac muscle cell hypertrophy by inhibiting activation of the Ras-MAP kinase signaling …
- Antiproliferative effect of Genistein and adriamycin against estrogen-dependent and-independent human breast carcinoma cell lines.
- Genistein and daidzein/glycitein content in tofu
- Genistein, a tyrosine kinase inhibitor, reduces Ca2+ mobilization in swine carotid media
- Effects of chronic dietary exposure to Genistein, a phytoestrogen, during various stages of development on reproductive hormones and spermatogenesis in rats
- Effects of Genistein and daidzein on the cell growth, cell cycle, and differentiation of human and murine melanoma cells
- Effect of Genistein-enriched diets on the endocrine process of gametogenesis and on reproduction efficiency of the rainbow trout Oncorhynchus mykiss
- Effect of Genistein on Steroid Hormone Production in the Pregnant Rhesus Monkey (44431)
- ELISA as a new method to measure Genistein and daidzein in food and human fluids
- Bioavailability of Genistein, daidzein, and their glycosides in intestinal epithelial Caco-2 cells
- Combined intervention of exercise and Genistein prevented androgen deficiency-induced bone loss in mice
- Genistein, an isoflavone included in soy, inhibits thrombotic vessel occlusion in the mouse femoral artery and in vitro platelet aggregation
- Combined effects of dietary phytoestrogen and synthetic endocrine-active compound on reproductive development in Sprague-Dawley rats: Genistein and …
- Genistein accumulation in soybean (Glycine max [L.] Merr.) root systems under suboptimal root zone temperatures
- Genistein inhibits cardiac L-type Ca2+ channel activity by a tyrosine kinase-independent mechanism
- Anti‐cancer effect of Genistein in oral squamous cell carcinoma with respect to angiogenesis and in vitro invasion
- Inhibition of choriocapillaris regeneration with Genistein.
- Genistein inhibits growth of B16 melanoma cells in vivo and in vitro and promotes differentiation in vitro
- Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: possible involvement of inhibition of survival signal …
- Inhibition by Genistein of prolactin-induced Nb2 lymphoma cell mitogenesis
- Differential effect of Genistein on transforming growth factor beta 1 expression in normal and malignant mammary epithelial cells.
- Effects of Genistein on cell proliferation and cell cycle arrest in nonneoplastic human mammary epithelial cells: involvement of Cdc2, p21waf/cip1, p27kip1, and …
- … compounds. 23. Synthesis of polyhydroxylated 2-phenylbenzothiazoles and a comparison of their cytotoxicities and pharmacological properties with Genistein and …
- Effects of tyrphostins and Genistein on the circulatory failure and organ dysfunction caused by endotoxin in the rat: a possible role for protein tyrosine kinase
- Attenuation by Genistein of sodium‐chloride‐enhanced gastric carcinogenesis induced by N‐methyl‐N′‐nitro‐N‐nitrosoguanidine in Wistar rats
- Baicalein and Genistein display differential actions on estrogen receptor (ER) transactivation and apoptosis in MCF-7 cells
- Phosphotyrosine inhibition and control of vascular endothelial cell proliferation by Genistein
- Effects of Genistein and daidzein on membrane characteristics of HCT cells
- Oestrogenic response of the CD-1 mouse to the soya-bean isoflavones Genistein, genistin and daidzin
- Effects of the tyrosine protein kinase inhibitor Genistein on the proliferation, activation of cultured rat hepatic stellate cells
- p21CIP1 is dispensable for the G2 arrest caused by Genistein in human melanoma cells
- Dose-response characteristics of neonatal exposure to Genistein on pituitary responsiveness to gonadotropin releasing hormone and volume of the sexually …
- Distinct Chk2 activation pathways are triggered by Genistein and DNA-damaging agents in human melanoma cells
- Genistein and daidzein stimulate hyaluronic acid production in transformed human keratinocyte culture and hairless mouse skin
- Genistein, a protein tyrosine kinase inhibitor, ameliorates retinal degeneration after ischemia-reperfusion injury in rat.
- Protein tyrosine kinase inhibitor, Genistein, enhances apoptosis and cell cycle arrest in K562 cells treated with γ-irradiation
- Inhibition of Vascular Smooth Muscle Cell K+ Currents by Tyrosine Kinase Inhibitors Genistein and ST 638
- Dietary diethylstilbestrol but not Genistein adversely affects rat testicular development
- Two mechanisms of Genistein inhibition of cystic fibrosis transmembrane conductance regulator Cl− channels expressed in murine cell line
- Effects of the isoflavone 4′, 5, 7-trihydroxyisoflavone (Genistein) on psoralen plus ultraviolet A radiation (PUVA)-induced photodamage
- Effects of Genistein and lavendustin on reproductive processes in domestic animals in vitro
- Tyrosine kinase-independent inhibition of cyclic-AMP phosphodiesterase by Genistein and tyrphostin 51
- Determination of the isoflavonoids Genistein and daidzein in biological samples by gas chromatography-mass spectrometry
- Acceleration of MRP-associated efflux of rhodamine 123 by Genistein and related compounds
- Genistein, a soy isoflavone, enhances necrotic-like cell death in a breast cancer cell treated with a chemotherapeutic agent.
- Inhibition of growth and induction of differentiation of metastatic melanoma cells in vitro by Genistein: chemosensitivity is regulated by cellular p53
- Activation of deltaF508 CFTR in a cystic fibrosis respiratory epithelial cell line by 4-phenylbutyrate, Genistein and CPX
- Dietary fructooligosaccharides modify intestinal bioavailability of a single dose of Genistein and daidzein and affect their urinary excretion and kinetics in blood of rats
- Anabolic effect of Genistein on bone metabolism in the femoral-metaphyseal tissues of elderly rats is inhibited by the anti-estrogen tamoxifen
- Changes in serum enterolactone, Genistein, and daidzein in a dietary intervention study in Finland
- Genistein modulates neuroblastoma cell proliferation and differentiation through induction of apoptosis and regulation of tyrosine kinase activity and N-myc expression …
- Rapid gut transit time and slow fecal isoflavone disappearance phenotype are associated with greater Genistein bioavailability in women
- Prepubertal Genistein treatment modulates TGF-α, EGF and EGF-receptor mRNAs and proteins in the rat mammary gland
- Genistein activates p38 mitogen-activated protein kinase, inactivates ERK1/ERK2 and decreases Cdc25C expression in immortalized human mammary epithelial …
- Synergistic effects of thearubigin and Genistein on human prostate tumor cell (PC-3) growth via cell cycle arrest
- Impact of dietary exposure to methoxychlor, Genistein, or diisononyl phthalate during the perinatal period on the development of the rat endocrine/reproductive …
- The mediating role of caspase‐3 protease in the intracellular mechanism of Genistein‐induced apoptosis in human prostatic carcinoma cell lines, DU145 and LNCaP
- Reduction of Genistein clastogenicity in Chinese hamster V79 cells by daidzein and other flavonoids
- Genistein increases the sensitivity of cardiac ion channels to β-adrenergic receptor stimulation
- Genistein, a soybean isoflavone, inhibits inward rectifier K+ channels in rat osteoclasts
- Determination of daidzein and Genistein in soybean foods by automated on-line in-tube solid-phase microextraction coupled to high-performance liquid …
- Lack of adverse effects in the F1 offspring maternally exposed to Genistein at human intake dose level
- The isoflavone Genistein inhibits internalization of enteric bacteria by cultured Caco-2 and HT-29 enterocytes
- Transcellular transport of Genistein, a soybean‐derived isoflavone, across human colon carcinoma cell line (Caco‐2)
- Synergistic effect of Genistein and BCNU on growth inhibition and cytotoxicity of glioblastoma cells
- The phytoestrogen Genistein enhances endothelium-independent relaxation in the porcine coronary artery
- Cytokine induction of iNOS and sPLA2 in immortalized astrocytes (DITNC): response to Genistein and pyrrolidine dithiocarbamate
- Inhibition of human breast cancer growth by GCP™(Genistein combined polysaccharide) in xenogeneic athymic mice: involvement of Genistein biotransformation by β …
- Modulation of mammary gland development in prepubertal male rats exposed to Genistein and methoxychlor
- Effect of the tyrosine kinase inhibitor, Genistein, on interleukin-1 stimulated PGE2 production in mesangial cells
- Preventive effects of isoflavones, Genistein and daidzein, on estradiol‐17β‐related endometrial carcinogenesis in mice
- DING, a Genistein target in human breast cancer: a protein without a gene
- Genistein restores functional interactions between ΔF508-CFTR and ENaC in Xenopus oocytes
- Early exposure to Genistein exerts long-lasting effects on the endocrine and immune systems in rats
- Inhibition of estrogenic stimulation of gene expression by Genistein
- Influence of Genistein (4′, 5, 7‐trihydroxyisoflavone) on the growth and proliferation of testicular cell lines
- Genistein complexes with amines: structure and properties
- Caspase‐3 protease activation during the process of Genistein‐induced apoptosis in TM4 testicular cells
- Vasoactive intestinal peptide, forskolin, and Genistein increase apical CFTR trafficking in the rectal gland of the spiny dogfish, Squalus acanthias. Acute regulation of …
- Neonatal exposure to Genistein reduces expression of estrogen receptor alpha and androgen receptor in testes of adult mice
- Anticarcinogenic effects of isoflavones may be mediated by Genistein in mouse mammary tumor virus-induced breast cancer
- Synthesis of novel mammalian metabolites of the isoflavonoid phytoestrogens daidzein and Genistein
- Synthesis of D4-Genistein, a stable deutero labeled isoflavone, by a perdeuteration—selective dedeuteration approach
- The effect of Genistein on the fertility of mice
- Chemosensitivity of human prostate cancer cells PC3 and LNCaP to Genistein isoflavone and β‐lapachone
- Why B-ring is the active center for Genistein to scavenge peroxyl radical: a DFT study
- Effect of norethisterone acetate, dimethylstilboestrol, Genistein and coumestrol on uptake of [3H] oestradiol by uterus, vagina and skeletal muscle of immature mice
- Genistein increases metallothionein expression in human intestinal cells, Caco-2
- Microbial Hydroxylation and Methylation of Genistein by Streptomycetes
- Genistein alters growth but is not toxic to the rat prostate
- Dietary soy oil content and soy‐derived phytoestrogen Genistein increase resistance to alopecia areata onset in C3H/HeJ mice
- Effect of prenatal and prepubertal Genistein exposure on N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats.
- Effect of human dietary exposure levels of Genistein during gestation and lactation on long-term reproductive development and sperm quality in mice
- Correction of G551D‐CFTR transport defect in epithelial monolayers by Genistein but not by CPX or MPB‐07
- Effect of Genistein on replication of bovine herpesvirus type 1
- Potentiation of the antiproliferative effect in vitro of doxorubicin, cisplatin and Genistein by new analogues of vitamin D.
- P21 response to DNA damage induced by Genistein and etoposide in human lung cancer cells
- Genistein inhibits slow component delayed-rectifier K currents via a tyrosine kinase-independent pathway
- Acute and chronic effects of Genistein, tyrphostin and lavendustin A on steroid synthesis in luteinized human granulosa cells
- Multigenerational exposure to dietary Genistein has no severe effects on nursing behavior in rats.
- Reciprocal control of expression of mRNAs for osteoclast differentiation factor and OPG in
