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    Icariin
    January 16, 2020
    Gossypol
    January 17, 2020
    1. Exercise prevents diet-induced cellular senescence in adipose tissue
    2. Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
    3. Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
    4. Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
    5. Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue
    6. Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities
    7. The emerging role of senescent cells in tissue homeostasis and pathophysiology
    8. Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
    9. JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
    10. Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
    11. Aging-related inflammation in osteoarthritis
    12. Cellular senescence in type 2 diabetes: a therapeutic opportunity
    13. The fat cell senescence hypothesis: a mechanism responsible for abrogating the resolution of inflammation in chronic disease
    14. Feast and famine: adipose tissue adaptations for healthy aging
    15. Macrophages in age-related chronic inflammatory diseases
    16. Proposed metabolic vicious circle in patients with large myocardial infarcts and high plasma-free-fatty-acid concentrations
    17. Perspective: targeting the JAK/STAT pathway to fight age-related dysfunction
    18. Effect of low-dose rapamycin on senescence markers and physical functioning in older adults with coronary artery disease: results of a pilot study.
    19. Systemic DNA damage response and metabolic syndrome as a premalignant state
    20. Stem cell senescence and regenerative paradigms
    21. Cellular senescence in ageing, age-related disease and longevity
    22. Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
    23. Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process
    24. Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
    25. Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic
    26. Cellular senescence in aging and age-related disease: from mechanisms to therapy
    27. Deleted in B reast C ancer 1 regulates cellular senescence during obesity
    28. Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
    29. Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
    30. Impact of growth hormone on regulation of adipose tissue
    31. Senescence-associated secretory phenotype (SASP) involvement in the development of cancer, aging, and age related diseases
    32. Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
    33. Curcumin, inflammation, ageing and age-related diseases
    34. Inflammation, ageing and chronic disease
    35. Geroscience: linking aging to chronic disease
    36. Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
    37. Mitochondrial dysfunction meets senescence
    38. Finding Shangri-La: limiting the impact of senescence on aging
    39. Inflamm-ageing
    40. Characterization of senescence of culture-expanded human adipose-derived mesenchymal stem cells
    41. An experiment to determine the active therapeutic moiety of sulphasalazine
    42. Aging of the human innate immune system in HIV infection
    43. Metabolic syndrome is a real disease and premalignant state induced by oncogenic stresses to block malignant transformation
    44. Mechanisms and metabolic implications of regional differences among fat depots
    45. The role of inflammation in age-related disease
    46. “Inflammaging” as a druggable target: a senescence-associated secretory phenotype—centered view of type 2 diabetes
    47. Antagonizing Effects of Aspartic Acid against Ultraviolet A-Induced Downregulation of the Stemness of Human adipose tissue-Derived Mesenchymal Stem …
    48. Cellular senescence: from physiology to pathology
    49. RETRACTED: Chronic Inflammation: Accelerator of Biological Aging
    50. Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?
    51. Cellular senescence and the biology of aging, disease, and frailty
    52. Targeting senescent cells enhances adipogenesis and metabolic function in old age
    53. Urinary Iodine Concentrations in Mothers and their Term Newborns
    54. Aging and osteoarthritis
    55. Obesity-associated mechanisms of hepatocarcinogenesis
    56. P12 Pathological vascular smooth muscle cells remodelling in murine models of abdominal aortic aneurysm
    57. The aging adipose organ: lipid redistribution, inflammation, and cellular senescence
    58. Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis
    59. Impact of cellular senescence signature on ageing research
    60. Metabolic and microenvironment changes in the mammary of calorie restricted, normal weight, and obese mice throughout the lifespan
    61. Senescent cells: a novel therapeutic target for aging and age‐related diseases
    62. … and Metabolic Dysfunction during Aging and Senescence: Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte …
    63. Crossing Boundaries to Propel Tissue Engineering into the Clinic
    64. Mitochondrial damage induces senescence with a twisted arm
    65. Therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis
    66. Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
    67. Pathogenesis of hepatocellular carcinoma development in non-alcoholic fatty liver disease
    68. ÔØ Å ÒÙ× Ö ÔØ
    69. Aging of the immune system: focus on inflammation and vaccination
    70. Molecular mechanisms of ageing and related diseases
    71. Senescent cells: SASPected drivers of age-related pathologies
    72. Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging
    73. p21 both attenuates and drives senescence and aging in BubR1 progeroid mice
    74. Stop feeding cancer: pro-inflammatory role of visceral adiposity in liver cancer
    75. Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
    76. Metabolic control of longevity
    77. Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells
    78. Microbiome–Obesity–Liver Cancer Interaction: Senescence of Hepatic Stellate Cells and Bile Acids Play New Roles
    79. Ameliorative effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats
    80. Hepatocellular carcinoma and lifestyles
    81. Inflammation and cellular senescence: potential contribution to chronic diseases and disabilities with aging
    82. Toll like receptor signaling in “inflammaging”: microRNA as new players
    83. Depleting senescent cells to combat aging
    84. www. aging-us. com AGING 2016, Vol. 8, Advance
    85. High-throughput screening reveals enzyme and GPCR targets as putative binding sites for d-deprenyl
    86. Adipocytes and neutrophils give a helping hand to pancreatic cancers
    87. Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
    88. Anti-inflammatory effects of Pulvis Fellis Suis extract in mice with ulcerative colitis
    89. Ageing and the pathogenesis of osteoarthritis
    90. Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
    91. Cellular senescence in aging and osteoarthritis: implications for cartilage repair
    92. Oxidative stress and the ageing endocrine system
    93. Clinical strategies and animal models for developing senolytic agents
    94. Liver cancer: connections with obesity, fatty liver, and cirrhosis
    95. Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging
    96. Age-dependent dysregulation of innate immunity
    97. Endothelial progenitor cells: from senescence to rejuvenation
    98. Aging: a common driver of chronic diseases and a target for novel interventions
    99. Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis
    100. Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
    101. The role of oxidative stress and inflammation in cardiovascular aging
    102. Cell autonomous and non-autonomous effects of senescent cells in the skin
    103. A case of rheumatoid arthritis exhibiting accelerating rheumatoid pleurisy during low-dose weekly methotrexate therapy
    104. Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
    105. The role of senescent cells in ageing
    106. Sowing the seeds of cancer: telomeres and age-associated tumorigenesis
    107. Tim-3: an emerging target in the cancer immunotherapy landscape
    108. Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats
    109. Diabetes and cancer, common threads and missing links
    110. Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors
    111. Translational research in immune senescence: assessing the relevance of current models
    112. Elimination of p19ARF-expressing cells enhances pulmonary function in mice
    113. The effects of aging on the development of osteoarthritis
    114. Cellular senescence impact on immune cell fate and function
    115. Effects of proanthocyanidins from grape seed on treatment of recurrent ulcerative colitis in rats
    116. Proanthocyanidins from grape seeds modulate the NF-κB signal transduction pathways in rats with TNBS-induced ulcerative colitis
    117. Morphological, molecular and functional differences of adult bone marrow-and adipose-derived stem cells isolated from rats of different ages
    118. The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development–a potential therapeutic target?
    119. Nonalcoholic fatty liver disease: pathogenesis and disease spectrum
    120. The possible mechanisms of Picrasma quassiodes (D. Don) Benn. in the treatment of colitis induced by 2, 4, 6-trinitrobenzene sulfonic acid in mice
    121. Aldosterone induces p21‐regulated apoptosis via increased synthesis and secretion of tumour necrosis factor‐α in human proximal tubular cells
    122. Senescence as a general cellular response to stress: a mini-review
    123. Obesity and liver cancer
    124. Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model
    125. Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells
    126. Histone macroH2A1. 2 promotes metabolic health and leanness by inhibiting adipogenesis
    127. Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis
    128. Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis
    129. Maternal obesity programs senescence signaling and glucose metabolism in osteo-progenitors from rat and human
    130. Immunosurveillance of senescent cells: the bright side of the senescence program
    131. Obesity and the gut microbiome: pathophysiological aspects
    132. Ageing induced vascular smooth muscle cell senescence in atherosclerosis
    133. Cancer and inflammation: an old intuition with rapidly evolving new concepts
    134. Obesity and cancer pathogenesis
    135. Metabolic consequences of HIV: pathogenic insights
    136. Noncoding RNA control of cellular senescence
    137. Protective effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats
    138. Inflammaging decreases adaptive and innate immune responses in mice and humans
    139. Senescence and the pro-tumorigenic stroma
    140. Siegesbeckia pubescens ameliorates experimental ulcerative colitis in rats by modulating PPARγ.
    141. Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis
    142. Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors
    143. Serum n3 polyunsaturated fatty acids are depleted in Crohn’s disease
    144. The cell secretome, a mediator of cell-to-cell communication
    145. Targeting senescent cells: possible implications for delaying skin aging: a mini-review
    146. DNA damage and innate immunity: links and trade-offs
    147. The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
    148. Protective effect of taurohyodeoxycholic acid from Pulvis Fellis Suis on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
    149. Chronic inflammation, immune escape, and oncogenesis in the liver: a unique neighborhood for novel intersections
    150. Mesenchymal stem cells in regenerative medicine: focus on articular cartilage and intervertebral disc regeneration
    151. Interventions to slow aging in humans: are we ready?
    152. Anti-inflammatory activity and mechanisms of a lipid extract from hard-shelled mussel (Mytilus coruscus) in mice with dextran sulphate sodium-induced colitis
    153. DNA damage response and autophagy: a meaningful partnership
    154. NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
    155. mTOR signaling from cellular senescence to organismal aging
    156. Erdheim–Chester disease: from palliative care to targeted treatment
    157. Gerosuppressant metformin: less is more
    158. Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents
    159. Workshop report Key data from the 11th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV
    160. Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
    161. Immune aging, dysmetabolism, and inflammation in neurological diseases
    162. Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis
    163. Conditioned media from human umbilical cord blood-derived mesenchymal stem cells inhibits melanogenesis by promoting proteasomal degradation of MITF
    164. Speeding up the clock: The past, present and future of progeria
    165. Mathematical integration of protein metabolism in growing lambs
    166. Short telomeres in key tissues initiate local and systemic aging in zebrafish
    167. Modelling age-related metabolic disorders in the mouse
    168. Disease drivers of aging
    169. Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
    170. Diabetes and aging
    171. Exercise attenuates the major hallmarks of aging
    172. Long noncoding RNAs in diseases of aging
    173. Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation
    174. From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
    175. Persistent DNA damage‐induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
    176. Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming
    177. Obesity and cancer
    178. Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
    179. Bile acids and the gut microbiome
    180. Aging, clonality, and rejuvenation of hematopoietic stem cells
    181. Dysregulated inflammation as a risk factor for pneumonia in the elderly
    182. Ageing and the telomere connection: An intimate relationship with inflammation
    183. The study of skeletal aging is coming of age: A forum on aging and skeletal health
    184. Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 …
    185. Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
    186. Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
    187. SYSTEMIC DNA DAMAGE RESPONSE AND METABOLIC SYNDROME
    188. Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells
    189. Are there roles for brain cell senescence in aging and neurodegenerative disorders?
    190. Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
    191. Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
    192. NF-κB in aging and disease
    193. Toward the comprehensive understanding of the gut ecosystem via metabolomics-based integrated omics approach
    194. Interleukin‐8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor‐α and interleukin‐1β
    195. Energetic interventions for healthspan and resiliency with aging
    196. Secretome of human fetal mesenchymal stem cell ameliorates replicative senescence
    197. Caloric restriction and aging stem cells: the stick and the carrot?
    198. Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity
    199. The promise of slow down ageing may come from curcumin
    200. Effects of mimic of manganese superoxide dismutase on 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats
    201. Genome-wide chromatin state transitions associated with developmental and environmental cues
    202. Oxidative stress, cellular senescence and ageing
    203. 7 Immune Senescence
    204. What Is Homeostasis?
    205. Atypical pyoderma gangrenosum with leukemia
    206. INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
    207. Vascular wall-resident multipotent stem cells of mesenchymal nature within the process of vascular remodeling: cellular basis, clinical relevance, and …
    208. Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells
    209. Senescence in chronic obstructive pulmonary disease
    210. Fibrogenesis and carcinogenesis in nonalcoholic steatohepatitis (NASH): involvement of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase …
    211. Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention
    212. Telomeres and age-related disease: how telomere biology informs clinical paradigms
    213. Characterization of the human salivary proteome by capillary isoelectric focusing/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS
    214. Macromolecular degradation systems and cardiovascular aging
    215. Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells
    216. Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
    217. Understanding The Regulation Of Adipogenesis And Adipocyte Metabolism In Obesity
    218. Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
    219. The senescence arrest program and the cell cycle
    220. The posttranslational processing of prelamin A and disease
    221. Caveolae and signalling in cancer
    222. Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasis
    223. Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults
    224. From experimental design to functional gene networks: DNA microarray contribution to skin ageing research
    225. Senescence-associated MCP-1 secretion is dependent on a decline in BMI1 in human mesenchymal stromal cells
    226. Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment
    227. Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice
    228. Living Large: What Mouse Models Reveal about Growth Hormone and Obesity
    229. Signaling networks determining life span
    230. Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity
    231. The second international conference “genetics of aging and longevity”
    232. Amniotic epithelial cells: a new tool to combat aging and age-related diseases?
    233. Mesenchymal stem cells in wound repair, tissue homeostasis, and aging
    234. The role and regulation of the nuclear factor kappa B signalling pathway in human labour
    235. Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions
    236. At the stem of youth and health
    237. New Insights into the Management and Therapeutics of Type 2 Diabetes
    238. Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid
    239. Cellular and molecular biology of aging endothelial cells
    240. The nuclear lamina in health and disease
    241. The Biology of Aging: Role in Cancer, Metabolic Dysfunction, and Health Disparities
    242. Cellular and molecular basis of the imbalance between vascular damage and repair in ageing and age-related diseases: as biomarkers and targets for new …
    243. Interrater reliability of a clinical scale to assess knee joint effusion
    244. Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
    245. Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
    246. Biomarkers and Inflammatory Network in Aging: Targets for Therapies
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    249. Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence
    250. MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1
    251. Identification of senescent cells in the bone microenvironment
    252. Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress
    253. Melatonin and the theories of aging: a critical appraisal of melatonin’s role in antiaging mechanisms
    254. Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
    255. Extracellular microRNAs and endothelial hyperglycemic memory: a therapeutic opportunity?
    256. Skin mirrors human aging
    257. miR‐335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP‐1 activity
    258. Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
    259. Illuminating inflammasome activity in vivo
    260. Metabolic exchanges within tumor microenvironment
    261. Inflammation and atherosclerosis in rheumatoid arthritis
    262. From cellular senescence to age-associated diseases: the miRNA connection
    263. Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin‐deficient mice
    264. Modulation of Membrane Transport Systems
    265. The role of chromatin reorganization in the process of cellular senescence
    266. Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals
    267. Role of DNA damage in cardiovascular disease
    268. The telomere syndromes
    269. Somatic stem cell aging and malignant transformation–impact on therapeutic application
    270. Organelle Stress and mTOR in Aging-Associated Inflammation
    271. ACC 284
    272. Regulatory roles of miRNAs in aging
    273. Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells
    274. Mechanisms of metastatic tumor dormancy
    275. Liposarcoma
    276. Liposarcomas-proliferation, senescence and the role of DDIT3
    277. Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas
    278. Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes
    279. Progressive loss of SIRT1 with cell cycle withdrawal
    280. Targeting Senescent Cells to Improve Human Health
    281. Defining mesenchymal stromal cells responsiveness to IFNγ as a surrogate measure of suppressive potency
    282. The germline/soma dichotomy: implications for aging and degenerative disease
    283. Identifying of the causative genes in spontaneous mutant mouse strains by forward-reverse genetics
    284. Phenylbutyric Acid: simple structure-multiple effects
    285. The role of immunosenescence in the development of age-related diseases
    286. Melatonin reverses H2O2‐induced premature senescence in mesenchymal stem cells via the SIRT1‐dependent pathway
    287. Recent advances in mouse models of obesity-and nonalcoholic steatohepatitis-associated hepatocarcinogenesis
    288. Cellular senescence and vascular disease: novel routes to better understanding and therapy
    289. Telomeres, NAFLD and chronic liver disease
    290. The emergence of geromirs: A group of micrornas implicated in aging
    291. The Role of Stem Cell Genomic Instability in Aging
    292. Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
    293. Regulation of senescence by microRNA biogenesis factors
    294. Host resistance and immune aging
    295. Coming of age: molecular drivers of aging and therapeutic opportunities
    296. ISSN 0975-413X CODEN (USA): PCHHAX
    297. Finding Ponce de Leon’s Pill: challenges in screening for anti-aging molecules
    298. Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation
    299. An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer
    300. Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
    301. MicroRNAs linking inflamm-aging, cellular senescence and cancer
    302. Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial …
    303. Medial arterial calcification: an overlooked player in peripheral arterial disease
    304. Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury
    305. Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
    306. Inflammasomes: guardians of cytosolic sanctity
    307. As we age: Does slippage of quality control in the immune system lead to collateral damage?
    308. Anti-aging pharmacology: promises and pitfalls
    309. Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
    310. Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
    311. Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients
    312. The Disrupted Steady-State: Tipping the Balance in Favour of Cancer
    313. The Way Forward: Translation
    314. Intervention of aging and its effects on cellular health
    315. DNA damage response and immune defense: links and mechanisms
    316. Towards an evidence-based model of aging
    317. iPSCs as a major opportunity to understand and cure age-related diseases
    318. The biology of aging: 1985–2010 and beyond
    319. DNA damage: from chronic inflammation to age-related deterioration
    320. The emerging role of Notch pathway in ageing: focus on the related mechanisms in age-related diseases
    321. SPEAKER ABSTRACTS
    322. miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53–p21 and p16–pRB pathways
    323. Osteopontin, a key mediator expressed by senescent pulmonary vascular cells in pulmonary hypertension
    324. NF-κB signaling as a driver of ageing
    325. The Cellular Senescence Program
    326. Age-related changes in blood-brain barrier integrity in C57BL/6J mice
    327. Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing
    328. Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice
    329. The metabolic regulation of cellular ageing
    330. The inflammatory network: bridging senescent stroma and epithelial tumorigenesis
    331. Cellular senescence and inflammation in aging and age-related disease
    332. Influence of aging on the quantity and quality of human cardiac stem cells
    333. Prospects and challenges for the use of stem cell technologies to develop novel therapies for Parkinson disease
    334. Hypoxia-inducible histone lysine demethylases: impact on the aging process and age-related diseases
    335. Autophagy and cancer metabolism
    336. Assessing cell and organ senescence biomarkers
    337. Sphingolipids in inflammation: pathological implications and potential therapeutic targets
    338. ÔØ Å ÒÙ× Ö ÔØ
    339. Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer
    340. Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment
    341. Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
    342. Pathogenesis of osteoarthritis
    343. Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan
    344. Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
    345. Intestinal anti-inflammatory effect of the rhizome extracts of Menispermum dauricum DC. on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
    346. Biosprays: From the biomedical to the clinical sciences
    347. Influence of age and physical fitness on miRna-21, TGF-ß and its receptors in leukocytes of healthy women.
    348. Caspase inhibition switches doxorubicin-induced apoptosis to senescence
    349. MicroRNAs as mediators of the ageing process
    350. Modelling ageing and age-related disease
    351. PROTECTIVE EFFECT OF RICE BRAN WATER EXTRACT ON PANCREAS OF RATS FED A HIGH-FAT DIET
    352. New objective findings after whiplash injuries: high blood flow in painful cervical soft tissue: an ultrasound pilot study
    353. Genome integrity in aging: human syndromes, mouse models, and therapeutic options
    354. Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence
    355. Endothelial cell senescence and thrombosis: ageing clots
    356. A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease
    357. NAFLD and hepatocellular Carcinoma: how big a problem is this really?
    358. Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
    359. Oral submucous fibrosis: Review on mechanisms of pathogenesis and malignant transformation
    360. Extracellular vesicles in lung microenvironment and pathogenesis
    361. Vascular endothelial senescence: from mechanisms to pathophysiology
    362. Autoimmune atherosclerosis in 3D: how it develops, how to diagnose and what to do
    363. Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
    364. Stress-induced premature senescence of endothelial and endothelial progenitor cells
    365. Regulation of Senescence by microRNAs
    366. Muscle stem cell aging: regulation and rejuvenation
    367. kk journal of experimental biology.
    368. 2.20 Behcet’s disease and miscellaneous rheumatic conditions
    369. Inflammatory bowel disease part I: ulcerative colitis–pathophysiology and conventional and alternative treatment options
    370. The Buck Institute: An inside look
    371. Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
    372. Orphan technology: Unfunded early-stage bioscience is dropped off at the firehouse
    373. Computational approaches for the transcriptomics, proteomics and epigenetic analysis in adult stem cells
    374. The secret lives of stem cells: Unraveling the molecular basis of stem cell aging
    375. Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
    376. Global profiling and relative quantifiction of histones, histone PTMs and histone-modifying enzymes in mesenchymal stem cells using LC-MS/MS and a novel …
    377. The 10th World Congress on Inflammation
    378. Ms. No.: METHODS-D-15-00125 R1–Revised Version
    379. Are aging biomarkers clinically relevant in oncogeriatrics?
    380. Apocrine secretion: new insights into an old phenomenon
    381. Molecular links between cellular senescence, longevity and age-related diseases–a systems biology perspective
    382. Practical Laboratory Medicine
    383. Stop Aging Disease! ICAD 2014.
    384. PROGRESS REPORT ON THE ROLE OF MITOCHONDRIAL ISOCITRATE DEHYDROGENASE 2 IN AGE-RELATED HEARING LOSS IN MICE
    385. Impact of physical activity on immune function and inflammation in the elderly
    386. Four faces of cellular senescence
    387. Interventions to slow aging in humans: Are we ready?
    388. Determination of serum visfatin level in patients with Behcet disease, comparing with normal population
    389. Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration
    390. DNA damage: a main determinant of vascular aging
    391. The Role of Estrogen Deficiency in Skin Aging and Wound Healing
    392. Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs
    393. Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
    394. Salvianolic acid B restored impaired barrier function via downregulation of MLCK by microRNA-1 in rat colitis model
    395. IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
    396. Anti-stress gene response in cell and tissue ageing: role of transcription factor NF-E2-related factor-2 and effect of dietary activators
    397. Protective Effect of Paronychia argentea L. on Acetic Acid Induced Ulcerative Colitis in Mice by Regulating Antioxidant Parameters and Inflammatory Markers
    398. 7th Joint Meeting of the European Tissue Repair Society (ETRS) with the Wound Healing Society
    399. Human Amniotic Fluid Mesenchymal Stromal cells (AF-MSCs) are Less Prone to in vitro Senescence Process Compared with Bone Marrow MSCs
    400. The central role of muscle stem cells in regenerative failure with aging
    401. Modulation of ageing characteristics with an anti-ageing compound
    402. Insulin pathway and its correlation with ageing and longevity
    403. Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype
    404. Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
    405. Stem cells and cancer stem cells
    406. Nutritional Modulators of Cellular Senescence In Vitro
    407. Non‐cell autonomous or secretory tumor suppression
    408. The Aging Superorganism
    409. Systemic problems: a perspective on stem cell aging and rejuvenation
    410. Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds
    411. Pharmacotherapeutics ECG of the Month
    412. Molecular Mechanisms of Lycopene Actions on Liver Disease Outcomes
    413. Pathophysiological fundamentals of diabetic cardiomyopathy
    414. The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases
    415. The role of miRNAs in common inflammatory arthropathies: osteoarthritis and gouty arthritis
    416. Similarities in gene expression profiles during in vitro aging of primary human embryonic lung and foreskin fibroblasts
    417. Rescuing the regenerative capacity of human mesenchymal stem cells from the elderly
    418. Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
    419. Nuclear lamina defects cause ATM-dependent NF
    420. Interventions for age-related diseases: Shifting the paradigm
    421. An Arf-Egr-C
    422. Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
    423. Aging, Immunosenescence, and Cancer
    424. A causal role of ATM-and NEMO-dependent NF-κB activation in DNA damage-induced senescence and aging
    425. Effect of bisphenol A on stress-induced premature senescence
    426. Progerin Expression Disrupts Critical Adult Stem Cell Functions that Mediate Tissue Repair Primarily through a Mechanism that Permanently Farnesylates Lamin A
    427. Systemic DNA damage responses in aging and diseases
    428. Osteoarthritis in the Elderly
    429. MDM2 levels modulate the cellular senescence response to CDK4 inhibition
    430. Functional-structural plant modeling
    431. Placental origins of chronic disease
    432. Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities
    433. The Role of Integrated Omics in Elucidating the Gut Microbiota Health Potentials
    434. Allogeneic mesenchymal stem cells transplantation in patients with refractory RA
    435. Stress-Induced Senescence: Molecular Pathways
    436. Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
    437. Twist proteins as oxidative and hypoxic stress regulators
    438. The gut microbiota and the liver: implications for clinical practice
    439. The Epigenome and Aging
    440. Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants
    441. Glenn Workshop on the Biology of Aging and AFAR Grantee Conference| JOINT MEETING
    442. The hallmarks of fibroblast ageing
    443. Signaling Networks Controlling Cellular Senescence
    444. Evidences of Early Senescence in Multiple Myeloma Bone Marrow
    445. Systemic administration of WY-14643, a selective synthetic agonist of peroxisome proliferator activator receptor-alpha, alters spinal neuronal firing in a rodent model of …
    446. Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
    447. A potential role for miR-31 in osteoblastic transition of vascular smooth muscle cells and cortisol-induced osteoporosis
    448. Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression
    449. BLT2 Protects Skin from the Damage Caused by Type 2 Diabetes Hyperglycemia by Increasing NO Production Through the nNOS Expression
    450. Molecular mechanisms of aging in MTDNA mutator mice
    451. Reversing stem cell aging: Implications for vascular regeneration
    452. Targeting the tumor stroma as a novel therapeutic approach for prostate cancer
    453. The Role of Macrophage Migration Inhibitory Factor in Osteoarthritis
    454. Evidence supporting the utility of blood cell respiratory capacity as a systemic marker of mitochondrial health and biological age
    455. Circadian molecular clock in lung pathophysiology
    456. Stop Aging Disease! ICAD 2014
    457. Investigating the differential instructive roles of WT1’s isoforms
    458. Osteoporosis and mechanisms of skeletal aging
    459. Functional Enrichment Analysis
    460. mberHappily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
    461. Skin disease in laminopathy-associated premature aging
    462. Cellular and Molecular Mechanisms of Chronic Inflammation in Aging of Skeletal Muscle
    463. Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
    464. Histone methylation and aging: lessons learned from model systems
    465. Regulation of Phospholipase Isozymes by Nuclear Factor-κB in Human Gestational Tissues in Vitro
    466. Fluorescence Spectroscopy
    467. Psoriasis and inflammatory bowel disease: links and risks
    468. Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle …
    469. SIRT1 in endothelial cells as a novel target for the prevention of early vascular aging
    470. Cellular senescence as the causal nexus of aging
    471. MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells
    472. Basic Research
    473. Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
    474. Relationships Among Body Mass Index, Nutrition, Internalizing Symptoms, and Ethnic Identity of Cherokee Youth Attending a Private American Indian Secondary …
    475. The role of the stress response gene Gadd45b in senescence
    476. False discovery rate (FDR)
    477. FBA Analysis, Plant-Pathogen Interactions
    478. Influence of aging on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal stem cells
    479. Macrophage migration inhibitory factor regulates AKT signaling in hypoxic culture to modulate senescence of human mesenchymal stem cells
    480. Cell and molecular aging
    481. Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB
    482. Role of the nuclear envelope in regulation of ageing
    483. Chemotherapy-and Radiation-Induced Accelerated Senescence: Implications for Treatment Response, Tumor Progression and Cancer Survivorship
    484. Selenium and Senescence: Centering on Genome Maintenance
    485. Author statement
    486. Mechanisms of action of anti-TNF-α antibodies in inflammatory bowel disease
    487. Immortality: Myth or becoming Reality
    488. Skin, Mucosa and Menopause
    489. SUPPLEMENTARY TABLES
    490. Proteome analysis of formalin-fixed and paraffin-embedded tissue
    491. Framework Region (FR-IMGT)
    492. Frequent Pattern Mining
    493. Founders Effect
    494. Fisher’s Test
    495. Frequency
    496. Frequentist Approach
    497. Fitness
    498. Forward-scattered Light (FSC)
    499. Fluorescent Markers
    500. Fluorescence Microscopy
    501. Functional/Signature Network Module for Target Pathway/Gene Discovery
    502. Forward and Inverse Parameter Estimation for Metabolic Models
    503. Feature Selection
    504. Fitness Function
    505. Feedback Regulation
    506. Fibroblasts
    507. Feasibility
    508. Functional Modules and Complexes
    509. FunctionalityType
    510. Flux Balance Analysis
    511. Fokker–Planck Equation
    512. Faceted Browsing
    513. Fluorescence-activated Cell Sorting
    514. Flow Cytometry
    515. Frame Language
    516. Function, biological
    517. Feed Forward Loop
    518. Fluorophore
    519. Fluorescence Microscope
    520. False Pos