Icariin
January 16, 2020Gossypol
January 17, 2020- Exercise prevents diet-induced cellular senescence in adipose tissue
- Physiological aging: links among adipose tissue dysfunction, diabetes, and frailty
- Unbiased analysis of senescence associated secretory phenotype (SASP) to identify common components following different genotoxic stresses
- Aging and adipose tissue: potential interventions for diabetes and regenerative medicine
- Roles of chemokine ligand-2 (CXCL2) and neutrophils in influencing endothelial cell function and inflammation of human adipose tissue
- Ablation of XP-V gene causes adipose tissue senescence and metabolic abnormalities
- The emerging role of senescent cells in tissue homeostasis and pathophysiology
- Cellular senescence and the senescent secretory phenotype in age-related chronic diseases
- JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age
- Growth hormone action predicts age-related white adipose tissue dysfunction and senescent cell burden in mice
- Aging-related inflammation in osteoarthritis
- Cellular senescence in type 2 diabetes: a therapeutic opportunity
- The fat cell senescence hypothesis: a mechanism responsible for abrogating the resolution of inflammation in chronic disease
- Feast and famine: adipose tissue adaptations for healthy aging
- Macrophages in age-related chronic inflammatory diseases
- Proposed metabolic vicious circle in patients with large myocardial infarcts and high plasma-free-fatty-acid concentrations
- Perspective: targeting the JAK/STAT pathway to fight age-related dysfunction
- Effect of low-dose rapamycin on senescence markers and physical functioning in older adults with coronary artery disease: results of a pilot study.
- Systemic DNA damage response and metabolic syndrome as a premalignant state
- Stem cell senescence and regenerative paradigms
- Cellular senescence in ageing, age-related disease and longevity
- Contribution of adipose tissue inflammation to the development of type 2 diabetes mellitus
- Phytochemicals suppress nuclear factor-κB signaling: impact on health span and the aging process
- Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte progenitors
- Developments in our understanding of the effects of growth hormone on white adipose tissue from mice: implications to the clinic
- Cellular senescence in aging and age-related disease: from mechanisms to therapy
- Deleted in B reast C ancer 1 regulates cellular senescence during obesity
- Growth differentiation factor 6 derived from mesenchymal stem/stromal cells reduces age-related functional deterioration in multiple tissues
- Mitochondrial dysfunction induces senescence with a distinct secretory phenotype
- Impact of growth hormone on regulation of adipose tissue
- Senescence-associated secretory phenotype (SASP) involvement in the development of cancer, aging, and age related diseases
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- Curcumin, inflammation, ageing and age-related diseases
- Inflammation, ageing and chronic disease
- Geroscience: linking aging to chronic disease
- Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)
- Mitochondrial dysfunction meets senescence
- Finding Shangri-La: limiting the impact of senescence on aging
- Inflamm-ageing
- Characterization of senescence of culture-expanded human adipose-derived mesenchymal stem cells
- An experiment to determine the active therapeutic moiety of sulphasalazine
- Aging of the human innate immune system in HIV infection
- Metabolic syndrome is a real disease and premalignant state induced by oncogenic stresses to block malignant transformation
- Mechanisms and metabolic implications of regional differences among fat depots
- The role of inflammation in age-related disease
- “Inflammaging” as a druggable target: a senescence-associated secretory phenotype—centered view of type 2 diabetes
- Antagonizing Effects of Aspartic Acid against Ultraviolet A-Induced Downregulation of the Stemness of Human adipose tissue-Derived Mesenchymal Stem …
- Cellular senescence: from physiology to pathology
- RETRACTED: Chronic Inflammation: Accelerator of Biological Aging
- Senescence associated macrophages and “macroph-aging”: are they pieces of the same puzzle?
- Cellular senescence and the biology of aging, disease, and frailty
- Targeting senescent cells enhances adipogenesis and metabolic function in old age
- Urinary Iodine Concentrations in Mothers and their Term Newborns
- Aging and osteoarthritis
- Obesity-associated mechanisms of hepatocarcinogenesis
- P12 Pathological vascular smooth muscle cells remodelling in murine models of abdominal aortic aneurysm
- The aging adipose organ: lipid redistribution, inflammation, and cellular senescence
- Ginsenoside Rd attenuates the inflammatory response via modulating p38 and JNK signaling pathways in rats with TNBS-induced relapsing colitis
- Impact of cellular senescence signature on ageing research
- Metabolic and microenvironment changes in the mammary of calorie restricted, normal weight, and obese mice throughout the lifespan
- Senescent cells: a novel therapeutic target for aging and age‐related diseases
- … and Metabolic Dysfunction during Aging and Senescence: Effect of lipopolysaccharides on adipogenic potential and premature senescence of adipocyte …
- Crossing Boundaries to Propel Tissue Engineering into the Clinic
- Mitochondrial damage induces senescence with a twisted arm
- Therapeutic effect and mechanism of proanthocyanidins from grape seeds in rats with TNBS-induced ulcerative colitis
- Chronic inflammation (inflammaging) and its potential contribution to age-associated diseases
- Pathogenesis of hepatocellular carcinoma development in non-alcoholic fatty liver disease
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- Aging of the immune system: focus on inflammation and vaccination
- Molecular mechanisms of ageing and related diseases
- Senescent cells: SASPected drivers of age-related pathologies
- Control of p53 and NF-κB signaling by WIP1 and MIF: role in cellular senescence and organismal aging
- p21 both attenuates and drives senescence and aging in BubR1 progeroid mice
- Stop feeding cancer: pro-inflammatory role of visceral adiposity in liver cancer
- Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
- Metabolic control of longevity
- Cisplatin-induced mesenchymal stromal cells-mediated mechanism contributing to decreased antitumor effect in breast cancer cells
- Microbiome–Obesity–Liver Cancer Interaction: Senescence of Hepatic Stellate Cells and Bile Acids Play New Roles
- Ameliorative effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis and their mechanisms in rats
- Hepatocellular carcinoma and lifestyles
- Inflammation and cellular senescence: potential contribution to chronic diseases and disabilities with aging
- Toll like receptor signaling in “inflammaging”: microRNA as new players
- Depleting senescent cells to combat aging
- www. aging-us. com AGING 2016, Vol. 8, Advance
- High-throughput screening reveals enzyme and GPCR targets as putative binding sites for d-deprenyl
- Adipocytes and neutrophils give a helping hand to pancreatic cancers
- Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
- Anti-inflammatory effects of Pulvis Fellis Suis extract in mice with ulcerative colitis
- Ageing and the pathogenesis of osteoarthritis
- Aging of mice is associated with p16 (Ink4a)-and β-galactosidase-positive macrophage accumulation that can be induced in young mice by senescent cells
- Cellular senescence in aging and osteoarthritis: implications for cartilage repair
- Oxidative stress and the ageing endocrine system
- Clinical strategies and animal models for developing senolytic agents
- Liver cancer: connections with obesity, fatty liver, and cirrhosis
- Of flies, mice, and men: evolutionarily conserved tissue damage responses and aging
- Age-dependent dysregulation of innate immunity
- Endothelial progenitor cells: from senescence to rejuvenation
- Aging: a common driver of chronic diseases and a target for novel interventions
- Increased IL-6 secretion by aged human mesenchymal stromal cells disrupts hematopoietic stem and progenitor cells’ homeostasis
- Extracellular microRNAs and endothelial hyperglycaemic memory: a therapeutic opportunity?
- The role of oxidative stress and inflammation in cardiovascular aging
- Cell autonomous and non-autonomous effects of senescent cells in the skin
- A case of rheumatoid arthritis exhibiting accelerating rheumatoid pleurisy during low-dose weekly methotrexate therapy
- Mesenchymal stroma: primary determinant and therapeutic target for epithelial cancer
- The role of senescent cells in ageing
- Sowing the seeds of cancer: telomeres and age-associated tumorigenesis
- Tim-3: an emerging target in the cancer immunotherapy landscape
- Effect of traditional Chinese medicinal enemas on ulcerative colitis of rats
- Diabetes and cancer, common threads and missing links
- Hepatocellular carcinoma in nonalcoholic fatty liver: role of environmental and genetic factors
- Translational research in immune senescence: assessing the relevance of current models
- Elimination of p19ARF-expressing cells enhances pulmonary function in mice
- The effects of aging on the development of osteoarthritis
- Cellular senescence impact on immune cell fate and function
- Effects of proanthocyanidins from grape seed on treatment of recurrent ulcerative colitis in rats
- Proanthocyanidins from grape seeds modulate the NF-κB signal transduction pathways in rats with TNBS-induced ulcerative colitis
- Morphological, molecular and functional differences of adult bone marrow-and adipose-derived stem cells isolated from rats of different ages
- The role of insulin resistance in nonalcoholic steatohepatitis and liver disease development–a potential therapeutic target?
- Nonalcoholic fatty liver disease: pathogenesis and disease spectrum
- The possible mechanisms of Picrasma quassiodes (D. Don) Benn. in the treatment of colitis induced by 2, 4, 6-trinitrobenzene sulfonic acid in mice
- Aldosterone induces p21‐regulated apoptosis via increased synthesis and secretion of tumour necrosis factor‐α in human proximal tubular cells
- Senescence as a general cellular response to stress: a mini-review
- Obesity and liver cancer
- Cell senescence abrogates the therapeutic potential of human mesenchymal stem cells in the lethal endotoxemia model
- Reversing multiple age-related pathologies by controlling the senescence-associated secretory phenotype of stem cells
- Histone macroH2A1. 2 promotes metabolic health and leanness by inhibiting adipogenesis
- Pivotal role of Sirt6 in the crosstalk among ageing, metabolic syndrome and osteoarthritis
- Proanthocyanidins from grape seeds modulates the nuclear factor-kappa B signal transduction pathways in rats with TNBS-induced recurrent ulcerative colitis
- Maternal obesity programs senescence signaling and glucose metabolism in osteo-progenitors from rat and human
- Immunosurveillance of senescent cells: the bright side of the senescence program
- Obesity and the gut microbiome: pathophysiological aspects
- Ageing induced vascular smooth muscle cell senescence in atherosclerosis
- Cancer and inflammation: an old intuition with rapidly evolving new concepts
- Obesity and cancer pathogenesis
- Metabolic consequences of HIV: pathogenic insights
- Noncoding RNA control of cellular senescence
- Protective effects of 3, 4-oxo-isopropylidene-shikimic acid on experimental colitis induced by trinitrobenzenesulfonic acid in rats
- Inflammaging decreases adaptive and innate immune responses in mice and humans
- Senescence and the pro-tumorigenic stroma
- Siegesbeckia pubescens ameliorates experimental ulcerative colitis in rats by modulating PPARγ.
- Therapeutic effect of ginsenoside Rd in rats with TNBS-induced recurrent ulcerative colitis
- Mice deficient in Rbm38, a target of the p53 family, are susceptible to accelerated aging and spontaneous tumors
- Serum n3 polyunsaturated fatty acids are depleted in Crohn’s disease
- The cell secretome, a mediator of cell-to-cell communication
- Targeting senescent cells: possible implications for delaying skin aging: a mini-review
- DNA damage and innate immunity: links and trade-offs
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- Anti-inflammatory activity and mechanisms of a lipid extract from hard-shelled mussel (Mytilus coruscus) in mice with dextran sulphate sodium-induced colitis
- DNA damage response and autophagy: a meaningful partnership
- NF-κB pathway activators as potential ageing biomarkers: targets for new therapeutic strategies
- mTOR signaling from cellular senescence to organismal aging
- Erdheim–Chester disease: from palliative care to targeted treatment
- Gerosuppressant metformin: less is more
- Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents
- Workshop report Key data from the 11th International Workshop on Adverse Drug Reactions and Co-Morbidities in HIV
- Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy
- Immune aging, dysmetabolism, and inflammation in neurological diseases
- Anti-inflammatory effects of Huangqin tang extract in mice on ulcerative colitis
- Conditioned media from human umbilical cord blood-derived mesenchymal stem cells inhibits melanogenesis by promoting proteasomal degradation of MITF
- Speeding up the clock: The past, present and future of progeria
- Mathematical integration of protein metabolism in growing lambs
- Short telomeres in key tissues initiate local and systemic aging in zebrafish
- Modelling age-related metabolic disorders in the mouse
- Disease drivers of aging
- Myeloma cells can corrupt senescent mesenchymal stromal cells and impair their anti-tumor activity
- Diabetes and aging
- Exercise attenuates the major hallmarks of aging
- Long noncoding RNAs in diseases of aging
- Evolving concepts in the pathogenesis of NASH: beyond steatosis and inflammation
- From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
- Persistent DNA damage‐induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
- Halofuginone reduces the inflammatory responses of DSS-induced colitis through metabolic reprogramming
- Obesity and cancer
- Senescence in human mesenchymal stem cells: functional changes and implications in stem cell-based therapy
- Bile acids and the gut microbiome
- Aging, clonality, and rejuvenation of hematopoietic stem cells
- Dysregulated inflammation as a risk factor for pneumonia in the elderly
- Ageing and the telomere connection: An intimate relationship with inflammation
- The study of skeletal aging is coming of age: A forum on aging and skeletal health
- Resveratrol attenuates senescence of adipose-derived mesenchymal stem cells and restores their paracrine effects on promoting insulin secretion of INS-1 …
- Cancer-associated-fibroblasts and tumour cells: a diabolic liaison driving cancer progression
- Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
- SYSTEMIC DNA DAMAGE RESPONSE AND METABOLIC SYNDROME
- Secreted microvesicular miR‐31 inhibits osteogenic differentiation of mesenchymal stem cells
- Are there roles for brain cell senescence in aging and neurodegenerative disorders?
- Effect of Manuka honey and sulfasalazine in combination to promote antioxidant defense system in experimentally induced ulcerative colitis model in rats
- Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
- NF-κB in aging and disease
- Toward the comprehensive understanding of the gut ecosystem via metabolomics-based integrated omics approach
- Interleukin‐8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor‐α and interleukin‐1β
- Energetic interventions for healthspan and resiliency with aging
- Secretome of human fetal mesenchymal stem cell ameliorates replicative senescence
- Caloric restriction and aging stem cells: the stick and the carrot?
- Exercise enhances wound healing and prevents cancer progression during aging by targeting macrophage polarity
- The promise of slow down ageing may come from curcumin
- Effects of mimic of manganese superoxide dismutase on 2, 4, 6-trinitrobenzene sulfonic acid-induced colitis in rats
- Genome-wide chromatin state transitions associated with developmental and environmental cues
- Oxidative stress, cellular senescence and ageing
- 7 Immune Senescence
- What Is Homeostasis?
- Atypical pyoderma gangrenosum with leukemia
- INVESTIGATING MOLECULAR PATHWAYS OF ROS-INDUCED PRO-INFLAMMATORY SENESCENCE IN PREADIPOCYTES
- Vascular wall-resident multipotent stem cells of mesenchymal nature within the process of vascular remodeling: cellular basis, clinical relevance, and …
- Recombinant HSP70 and mild heat shock stimulate growth of aged mesenchymal stem cells
- Senescence in chronic obstructive pulmonary disease
- Fibrogenesis and carcinogenesis in nonalcoholic steatohepatitis (NASH): involvement of matrix metalloproteinases (MMPs) and tissue inhibitors of metalloproteinase …
- Non-alcoholic steatohepatitis and hepatocellular carcinoma: implications for lycopene intervention
- Telomeres and age-related disease: how telomere biology informs clinical paradigms
- Characterization of the human salivary proteome by capillary isoelectric focusing/nanoreversed-phase liquid chromatography coupled with ESI-tandem MS
- Macromolecular degradation systems and cardiovascular aging
- Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells
- Identification of a novel senolytic agent, navitoclax, targeting the Bcl‐2 family of anti‐apoptotic factors
- Understanding The Regulation Of Adipogenesis And Adipocyte Metabolism In Obesity
- Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture
- The senescence arrest program and the cell cycle
- The posttranslational processing of prelamin A and disease
- Caveolae and signalling in cancer
- Therapy with multipotent mesenchymal stromal cells protects lungs from radiation-induced injury and reduces the risk of lung metastasis
- Frailty and sarcopenia as the basis for the phenotypic manifestation of chronic diseases in older adults
- From experimental design to functional gene networks: DNA microarray contribution to skin ageing research
- Senescence-associated MCP-1 secretion is dependent on a decline in BMI1 in human mesenchymal stromal cells
- Tumour biology of obesity-related cancers: understanding the molecular concept for better diagnosis and treatment
- Protective effect of sanguinarine against acetic acid-induced ulcerative colitis in mice
- Living Large: What Mouse Models Reveal about Growth Hormone and Obesity
- Signaling networks determining life span
- Invariant natural killer T cells recognize a fungal glycosphingolipid that can induce airway hyperreactivity
- The second international conference “genetics of aging and longevity”
- Amniotic epithelial cells: a new tool to combat aging and age-related diseases?
- Mesenchymal stem cells in wound repair, tissue homeostasis, and aging
- The role and regulation of the nuclear factor kappa B signalling pathway in human labour
- Physiological regulation of the heat shock response by glutamine: implications for chronic low-grade inflammatory diseases in age-related conditions
- At the stem of youth and health
- New Insights into the Management and Therapeutics of Type 2 Diabetes
- Epigallocatechin-3-gallate ameliorates rats colitis induced by acetic acid
- Cellular and molecular biology of aging endothelial cells
- The nuclear lamina in health and disease
- The Biology of Aging: Role in Cancer, Metabolic Dysfunction, and Health Disparities
- Cellular and molecular basis of the imbalance between vascular damage and repair in ageing and age-related diseases: as biomarkers and targets for new …
- Interrater reliability of a clinical scale to assess knee joint effusion
- Telomeres, oxidative stress and inflammatory factors: partners in cellular senescence?
- Cell cycle arrest and the evolution of chronic kidney disease from acute kidney injury
- Biomarkers and Inflammatory Network in Aging: Targets for Therapies
- Implications of multipotent mesenchymal stromal cell aging
- Connecting the dots: from DNA damage and repair to aging
- Metformin‐mediated increase in DICER1 regulates microRNA expression and cellular senescence
- MicroRNA-34a induces endothelial progenitor cell senescence and impedes its angiogenesis via suppressing silent information regulator 1
- Identification of senescent cells in the bone microenvironment
- Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress
- Melatonin and the theories of aging: a critical appraisal of melatonin’s role in antiaging mechanisms
- Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes?
- Extracellular microRNAs and endothelial hyperglycemic memory: a therapeutic opportunity?
- Skin mirrors human aging
- miR‐335 correlates with senescence/aging in human mesenchymal stem cells and inhibits their therapeutic actions through inhibition of AP‐1 activity
- Effect of different doses of Manuka honey in experimentally induced inflammatory bowel disease in rats
- Illuminating inflammasome activity in vivo
- Metabolic exchanges within tumor microenvironment
- Inflammation and atherosclerosis in rheumatoid arthritis
- From cellular senescence to age-associated diseases: the miRNA connection
- Melatonin reduces endoplasmic reticulum stress and autophagy in liver of leptin‐deficient mice
- Modulation of Membrane Transport Systems
- The role of chromatin reorganization in the process of cellular senescence
- Pleiotropic effects of tocotrienols and quercetin on cellular senescence: introducing the perspective of senolytic effects of phytochemicals
- Role of DNA damage in cardiovascular disease
- The telomere syndromes
- Somatic stem cell aging and malignant transformation–impact on therapeutic application
- Organelle Stress and mTOR in Aging-Associated Inflammation
- ACC 284
- Regulatory roles of miRNAs in aging
- Evidences of early senescence in multiple myeloma bone marrow mesenchymal stromal cells
- Mechanisms of metastatic tumor dormancy
- Liposarcoma
- Liposarcomas-proliferation, senescence and the role of DDIT3
- Senescence bypass in mesenchymal stem cells: a potential pathogenesis and implications of pro-senescence therapy in sarcomas
- Mechanisms of resveratrol-induced inhibition of clonal expansion and terminal adipogenic differentiation in 3T3-L1 preadipocytes
- Progressive loss of SIRT1 with cell cycle withdrawal
- Targeting Senescent Cells to Improve Human Health
- Defining mesenchymal stromal cells responsiveness to IFNγ as a surrogate measure of suppressive potency
- The germline/soma dichotomy: implications for aging and degenerative disease
- Identifying of the causative genes in spontaneous mutant mouse strains by forward-reverse genetics
- Phenylbutyric Acid: simple structure-multiple effects
- The role of immunosenescence in the development of age-related diseases
- Melatonin reverses H2O2‐induced premature senescence in mesenchymal stem cells via the SIRT1‐dependent pathway
- Recent advances in mouse models of obesity-and nonalcoholic steatohepatitis-associated hepatocarcinogenesis
- Cellular senescence and vascular disease: novel routes to better understanding and therapy
- Telomeres, NAFLD and chronic liver disease
- The emergence of geromirs: A group of micrornas implicated in aging
- The Role of Stem Cell Genomic Instability in Aging
- Potential therapeutic effects of curcumin, the anti-inflammatory agent, against neurodegenerative, cardiovascular, pulmonary, metabolic, autoimmune and neoplastic …
- Regulation of senescence by microRNA biogenesis factors
- Host resistance and immune aging
- Coming of age: molecular drivers of aging and therapeutic opportunities
- ISSN 0975-413X CODEN (USA): PCHHAX
- Finding Ponce de Leon’s Pill: challenges in screening for anti-aging molecules
- Thymic involution perturbs negative selection leading to autoreactive T cells that induce chronic inflammation
- An Arf-Egr-C/EBPβ pathway linked to ras-induced senescence and cancer
- Growth hormone is a cellular senescence target in pituitary and nonpituitary cells
- MicroRNAs linking inflamm-aging, cellular senescence and cancer
- Ionizing radiation promotes the acquisition of a senescence-associated secretory phenotype and impairs angiogenic capacity in cerebromicrovascular endothelial …
- Medial arterial calcification: an overlooked player in peripheral arterial disease
- Lessons from Hepatocyte-Specific Cyp51 Knockout Mice: Impaired Cholesterol Synthesis Leads to Oval Cell-Driven Liver Injury
- Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
- Inflammasomes: guardians of cytosolic sanctity
- As we age: Does slippage of quality control in the immune system lead to collateral damage?
- Anti-aging pharmacology: promises and pitfalls
- Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
- Effect of hyperglycemia on hepatocellular carcinoma development in diabetes
- Expression of HOXD9 in fibroblast-like synoviocytes from rheumatoid arthritis patients
- The Disrupted Steady-State: Tipping the Balance in Favour of Cancer
- The Way Forward: Translation
- Intervention of aging and its effects on cellular health
- DNA damage response and immune defense: links and mechanisms
- Towards an evidence-based model of aging
- iPSCs as a major opportunity to understand and cure age-related diseases
- The biology of aging: 1985–2010 and beyond
- DNA damage: from chronic inflammation to age-related deterioration
- The emerging role of Notch pathway in ageing: focus on the related mechanisms in age-related diseases
- SPEAKER ABSTRACTS
- miR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53–p21 and p16–pRB pathways
- Osteopontin, a key mediator expressed by senescent pulmonary vascular cells in pulmonary hypertension
- NF-κB signaling as a driver of ageing
- The Cellular Senescence Program
- Age-related changes in blood-brain barrier integrity in C57BL/6J mice
- Ultrastructural analysis of changes in neurons of the mouse internal anal sphincter during ageing
- Age-related changes to lumbosacral spinal cord motoneurons that modulate bladder and bowel functions in male C57BL/6 mice
- The metabolic regulation of cellular ageing
- The inflammatory network: bridging senescent stroma and epithelial tumorigenesis
- Cellular senescence and inflammation in aging and age-related disease
- Influence of aging on the quantity and quality of human cardiac stem cells
- Prospects and challenges for the use of stem cell technologies to develop novel therapies for Parkinson disease
- Hypoxia-inducible histone lysine demethylases: impact on the aging process and age-related diseases
- Autophagy and cancer metabolism
- Assessing cell and organ senescence biomarkers
- Sphingolipids in inflammation: pathological implications and potential therapeutic targets
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- Metformin and the ATM DNA damage response (DDR): accelerating the onset of stress-induced senescence to boost protection against cancer
- Cellular senescence in cardiovascular diseases: potential age-related mechanisms and implications for treatment
- Insulin-like growth factor binding proteins 4 and 7 released by senescent cells promote premature senescence in mesenchymal stem cells
- Pathogenesis of osteoarthritis
- Better living through chemistry: caloric restriction (CR) and CR mimetics alter genome function to promote increased health and lifespan
- Perspectives on translational and therapeutic aspects of SIRT1 in inflammaging and senescence
- Intestinal anti-inflammatory effect of the rhizome extracts of Menispermum dauricum DC. on trinitrobenzene sulfonic acid induced ulcerative colitis in mice
- Biosprays: From the biomedical to the clinical sciences
- Influence of age and physical fitness on miRna-21, TGF-ß and its receptors in leukocytes of healthy women.
- Caspase inhibition switches doxorubicin-induced apoptosis to senescence
- MicroRNAs as mediators of the ageing process
- Modelling ageing and age-related disease
- PROTECTIVE EFFECT OF RICE BRAN WATER EXTRACT ON PANCREAS OF RATS FED A HIGH-FAT DIET
- New objective findings after whiplash injuries: high blood flow in painful cervical soft tissue: an ultrasound pilot study
- Genome integrity in aging: human syndromes, mouse models, and therapeutic options
- Conditioned medium derived from rat amniotic epithelial cells confers protection against inflammation, cancer, and senescence
- Endothelial cell senescence and thrombosis: ageing clots
- A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease
- NAFLD and hepatocellular Carcinoma: how big a problem is this really?
- Mast cells and histamine are triggering the NF-κB-mediated reactions of adult and aged perilymphatic mesenteric tissues to acute inflammation
- Oral submucous fibrosis: Review on mechanisms of pathogenesis and malignant transformation
- Extracellular vesicles in lung microenvironment and pathogenesis
- Vascular endothelial senescence: from mechanisms to pathophysiology
- Autoimmune atherosclerosis in 3D: how it develops, how to diagnose and what to do
- Physiological roles of the DNA demethylation-associated proteins Gadd45a and Ing1
- Stress-induced premature senescence of endothelial and endothelial progenitor cells
- Regulation of Senescence by microRNAs
- Muscle stem cell aging: regulation and rejuvenation
- kk journal of experimental biology.
- 2.20 Behcet’s disease and miscellaneous rheumatic conditions
- Inflammatory bowel disease part I: ulcerative colitis–pathophysiology and conventional and alternative treatment options
- The Buck Institute: An inside look
- Accelerated epithelial cell senescence in IPF and the inhibitory role of SIRT6 in TGF-β-induced senescence of human bronchial epithelial cells
- Orphan technology: Unfunded early-stage bioscience is dropped off at the firehouse
- Computational approaches for the transcriptomics, proteomics and epigenetic analysis in adult stem cells
- The secret lives of stem cells: Unraveling the molecular basis of stem cell aging
- Positive and negative effects of cellular senescence during female reproductive aging and pregnancy
- Global profiling and relative quantifiction of histones, histone PTMs and histone-modifying enzymes in mesenchymal stem cells using LC-MS/MS and a novel …
- The 10th World Congress on Inflammation
- Ms. No.: METHODS-D-15-00125 R1–Revised Version
- Are aging biomarkers clinically relevant in oncogeriatrics?
- Apocrine secretion: new insights into an old phenomenon
- Molecular links between cellular senescence, longevity and age-related diseases–a systems biology perspective
- Practical Laboratory Medicine
- Stop Aging Disease! ICAD 2014.
- PROGRESS REPORT ON THE ROLE OF MITOCHONDRIAL ISOCITRATE DEHYDROGENASE 2 IN AGE-RELATED HEARING LOSS IN MICE
- Impact of physical activity on immune function and inflammation in the elderly
- Four faces of cellular senescence
- Interventions to slow aging in humans: Are we ready?
- Determination of serum visfatin level in patients with Behcet disease, comparing with normal population
- Senescent fibroblast-derived Chemerin promotes squamous cell carcinoma migration
- DNA damage: a main determinant of vascular aging
- The Role of Estrogen Deficiency in Skin Aging and Wound Healing
- Comparative analysis of gene expression data reveals novel targets of senescence-associated microRNAs
- Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
- Salvianolic acid B restored impaired barrier function via downregulation of MLCK by microRNA-1 in rat colitis model
- IL-6 and related cytokines as the critical lynchpins between inflammation and cancer
- Anti-stress gene response in cell and tissue ageing: role of transcription factor NF-E2-related factor-2 and effect of dietary activators
- Protective Effect of Paronychia argentea L. on Acetic Acid Induced Ulcerative Colitis in Mice by Regulating Antioxidant Parameters and Inflammatory Markers
- 7th Joint Meeting of the European Tissue Repair Society (ETRS) with the Wound Healing Society
- Human Amniotic Fluid Mesenchymal Stromal cells (AF-MSCs) are Less Prone to in vitro Senescence Process Compared with Bone Marrow MSCs
- The central role of muscle stem cells in regenerative failure with aging
- Modulation of ageing characteristics with an anti-ageing compound
- Insulin pathway and its correlation with ageing and longevity
- Glucocorticoids suppress selected components of the senescence‐associated secretory phenotype
- Altered glycolipid and glycerophospholipid signaling drive inflammatory cascades in adrenomyeloneuropathy
- Stem cells and cancer stem cells
- Nutritional Modulators of Cellular Senescence In Vitro
- Non‐cell autonomous or secretory tumor suppression
- The Aging Superorganism
- Systemic problems: a perspective on stem cell aging and rejuvenation
- Modulators of cellular senescence: mechanisms, promises, and challenges from in vitro studies with dietary bioactive compounds
- Pharmacotherapeutics ECG of the Month
- Molecular Mechanisms of Lycopene Actions on Liver Disease Outcomes
- Pathophysiological fundamentals of diabetic cardiomyopathy
- The gut microbial endocrine organ: bacterially derived signals driving cardiometabolic diseases
- The role of miRNAs in common inflammatory arthropathies: osteoarthritis and gouty arthritis
- Similarities in gene expression profiles during in vitro aging of primary human embryonic lung and foreskin fibroblasts
- Rescuing the regenerative capacity of human mesenchymal stem cells from the elderly
- Nuclear lamina defects cause ATM-dependent NF-κB activation and link accelerated aging to a systemic inflammatory response
- Nuclear lamina defects cause ATM-dependent NF
- Interventions for age-related diseases: Shifting the paradigm
- An Arf-Egr-C
- Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
- Aging, Immunosenescence, and Cancer
- A causal role of ATM-and NEMO-dependent NF-κB activation in DNA damage-induced senescence and aging
- Effect of bisphenol A on stress-induced premature senescence
- Progerin Expression Disrupts Critical Adult Stem Cell Functions that Mediate Tissue Repair Primarily through a Mechanism that Permanently Farnesylates Lamin A
- Systemic DNA damage responses in aging and diseases
- Osteoarthritis in the Elderly
- MDM2 levels modulate the cellular senescence response to CDK4 inhibition
- Functional-structural plant modeling
- Placental origins of chronic disease
- Inflammatory dysregulation and cancer: From molecular mechanisms to therapeutic opportunities
- The Role of Integrated Omics in Elucidating the Gut Microbiota Health Potentials
- Allogeneic mesenchymal stem cells transplantation in patients with refractory RA
- Stress-Induced Senescence: Molecular Pathways
- Neovascularization capacity of mesenchymal stromal cells from critical limb ischemia patients is equivalent to healthy controls
- Twist proteins as oxidative and hypoxic stress regulators
- The gut microbiota and the liver: implications for clinical practice
- The Epigenome and Aging
- Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants
- Glenn Workshop on the Biology of Aging and AFAR Grantee Conference| JOINT MEETING
- The hallmarks of fibroblast ageing
- Signaling Networks Controlling Cellular Senescence
- Evidences of Early Senescence in Multiple Myeloma Bone Marrow
- Systemic administration of WY-14643, a selective synthetic agonist of peroxisome proliferator activator receptor-alpha, alters spinal neuronal firing in a rodent model of …
- Development of a mouse model for Hutchinson-Gilford progeria syndrome reveal defects in adult stem cell maintenance
- A potential role for miR-31 in osteoblastic transition of vascular smooth muscle cells and cortisol-induced osteoporosis
- Senescent mesenchymal stem cells promote colorectal cancer cells growth via galectin-3 expression
- BLT2 Protects Skin from the Damage Caused by Type 2 Diabetes Hyperglycemia by Increasing NO Production Through the nNOS Expression
- Molecular mechanisms of aging in MTDNA mutator mice
- Reversing stem cell aging: Implications for vascular regeneration
- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer
- The Role of Macrophage Migration Inhibitory Factor in Osteoarthritis
- Evidence supporting the utility of blood cell respiratory capacity as a systemic marker of mitochondrial health and biological age
- Circadian molecular clock in lung pathophysiology
- Stop Aging Disease! ICAD 2014
- Investigating the differential instructive roles of WT1’s isoforms
- Osteoporosis and mechanisms of skeletal aging
- Functional Enrichment Analysis
- mberHappily (n) ever after: Aging in the context of oxidative stress, proteostasis loss and cellular senescence
- Skin disease in laminopathy-associated premature aging
- Cellular and Molecular Mechanisms of Chronic Inflammation in Aging of Skeletal Muscle
- Oxidative stress-induced JNK activation contributes to proinflammatory phenotype of aging diabetic mesangial cells
- Histone methylation and aging: lessons learned from model systems
- Regulation of Phospholipase Isozymes by Nuclear Factor-κB in Human Gestational Tissues in Vitro
- Fluorescence Spectroscopy
- Psoriasis and inflammatory bowel disease: links and risks
- Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle …
- SIRT1 in endothelial cells as a novel target for the prevention of early vascular aging
- Cellular senescence as the causal nexus of aging
- MicroRNAs Regulate p21Waf1/Cip1 Protein Expression and the DNA Damage Response in Human Embryonic Stem Cells
- Basic Research
- Nuclear matrix, nuclear envelope and premature aging syndromes in a translational research perspective
- Relationships Among Body Mass Index, Nutrition, Internalizing Symptoms, and Ethnic Identity of Cherokee Youth Attending a Private American Indian Secondary …
- The role of the stress response gene Gadd45b in senescence
- False discovery rate (FDR)
- FBA Analysis, Plant-Pathogen Interactions
- Influence of aging on proliferation, pluripotency, immunogenic profiles from bone marrow mesenchymal stem cells
- Macrophage migration inhibitory factor regulates AKT signaling in hypoxic culture to modulate senescence of human mesenchymal stem cells
- Cell and molecular aging
- Loss of HuR leads to senescence-like cytokine induction in rodent fibroblasts by activating NF-κB
- Role of the nuclear envelope in regulation of ageing
- Chemotherapy-and Radiation-Induced Accelerated Senescence: Implications for Treatment Response, Tumor Progression and Cancer Survivorship
- Selenium and Senescence: Centering on Genome Maintenance
- Author statement
- Mechanisms of action of anti-TNF-α antibodies in inflammatory bowel disease
- Immortality: Myth or becoming Reality
- Skin, Mucosa and Menopause
- SUPPLEMENTARY TABLES
- Proteome analysis of formalin-fixed and paraffin-embedded tissue
- Framework Region (FR-IMGT)
- Frequent Pattern Mining
- Founders Effect
- Fisher’s Test
- Frequency
- Frequentist Approach
- Fitness
- Forward-scattered Light (FSC)
- Fluorescent Markers
- Fluorescence Microscopy
- Functional/Signature Network Module for Target Pathway/Gene Discovery
- Forward and Inverse Parameter Estimation for Metabolic Models
- Feature Selection
- Fitness Function
- Feedback Regulation
- Fibroblasts
