BDNF acts on certain neurons of the central nervous system and the peripheral nervous system, helping to support survival of existing neurons, and encouraging growth and differentiation of new neurons and synapses.[10][11] In the brain it is active in the hippocampus, cortex, and basal forebrain—areas vital to learning, memory, and higher thinking.[12] BDNF is also expressed in the retina, kidneys, prostate, motor neurons, and skeletal muscle, and is also found in saliva.[13][14]
BDNF itself is important for long-term memory.[15] Although the vast majority of neurons in the mammalian brain are formed prenatally, parts of the adult brain retain the ability to grow new neurons from neural stem cells in a process known as neurogenesis. Neurotrophins are proteins that help to stimulate and control neurogenesis, BDNF being one of the most active.[16][17][18] Mice born without the ability to make BDNF suffer developmental defects in the brain and sensory nervous system, and usually die soon after birth, suggesting that BDNF plays an important role in normal neural development.[19] Other important neurotrophins structurally related to BDNF include NT-3, NT-4, and NGF.
BDNF is made in the endoplasmic reticulumand secreted from dense-core vesicles. It binds carboxypeptidase E (CPE), and disruption of this binding has been proposed to cause the loss of sorting BDNF into dense-core vesicles. The phenotype for BDNF knockout mice can be severe, including postnatal lethality. Other traits include sensory neuron losses that affect coordination, balance, hearing, taste, and breathing. Knockout mice also exhibit cerebellar abnormalities and an increase in the number of sympathetic neurons.[20]
Certain types of physical exercise have been shown to markedly (threefold) increase BDNF synthesis in the human brain, a phenomenon which is partly responsible for exercise-induced neurogenesis and improvements in cognitive function.[14][21][22][23][24] Niacinappears to upregulate BDNF and tropomyosin receptor kinase B (TrkB) expression as well.[25]
- BDNF is a neurotrophic factor for dopaminergic neurons of the substantia nigra
- The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function
- Distribution of brain-derived neurotrophic factor (BDNF) protein and mRNA in the normal adult rat CNS: evidence for anterograde axonal transport
- Regulation of BDNF and trkB mRNA in rat brain by chronic electroconvulsive seizure and antidepressant drug treatments
- Alterations of serum levels of brain-derived neurotrophic factor (BDNF) in depressed patients with or without antidepressants
- Ca2+ influx regulates BDNF transcription by a CREB family transcription factor-dependent mechanism
- Increased hippocampal BDNF immunoreactivity in subjects treated with antidepressant medication
- DNA methylation-related chromatin remodeling in activity-dependent BDNF gene regulation
- Antidepressant-like effect of brain-derived neurotrophic factor (BDNF)
- Recombinant BDNF rescues deficits in basal synaptic transmission and hippocampal LTP in BDNF knockout mice
- A BDNF autocrine loop in adult sensory neurons prevents cell death
- NT-3, BDNF, and NGF in the developing rat nervous system: parallel as well as reciprocal patterns of expression
- A controlled trial of recombinant methionyl human BDNF in ALS
- Targeted disruption of the BDNF gene perturbs brain and sensory neuron development but not motor neuron development
- BDNF regulates eating behavior and locomotor activity in mice
- Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
- Multiple promoters direct tissue-specific expression of the rat BDNF gene
- Loss of huntingtin-mediated BDNF gene transcription in Huntington’s disease
- … synthesis of brain-derived neurotrophic factor in the lesioned peripheral nerve: different mechanisms are responsible for the regulation of BDNF and NGF mRNA.
- Requirement for BDNF in activity-dependent survival of cortical neurons
- Activity dependent regulation of BDNF and NGF mRNAs in the rat hippocampus is mediated by non‐NMDA glutamate receptors.
- Reduced BDNF mRNA expression in the Parkinson’s disease substantia nigra
- BDNF and activity-dependent synaptic modulation
- Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity
- Learning deficit in BDNF mutant mice
- BDNF mRNA is decreased in the hippocampus of individuals with Alzheimer’s disease
- Neurotrophin-3: a neurotrophic factor related to NGF and BDNF
- Synaptic secretion of BDNF after high‐frequency stimulation of glutamatergic synapses
- BDNF controls dopamine D 3 receptor expression and triggers behavioural sensitization
- NT-3 and/or BDNF therapy prevents loss of auditory neurons following loss of hair cells.
- BDNF mRNA expression is increased in adult rat forebrain after limbic seizures: temporal patterns of induction distinct from NGF
- Rapid and selective induction of BDNF expression in the hippocampus during contextual learning
- Retrograde axonal transport of BDNF in retinal ganglion cells is blocked by acute IOP elevation in rats
- Postsynaptic induction of BDNF-mediated long-term potentiation
- BDNF regulates the maturation of inhibition and the critical period of plasticity in mouse visual cortex
- The neurotrophins BDNF, NT-3, and NGF display distinct patterns of retrograde axonal transport in peripheral and central neurons
- Complementary roles of BDNF and NT-3 in vestibular and auditory development
- Expression and function of TRK-B and BDNF in human neuroblastomas.
- BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells?
- Widespread expression of BDNF but not NT3 by target areas of basal forebrain cholinergic neurons
- Family-based association study of 76 candidate genes in bipolar disorder: BDNF is a potential risk locus
- NT-3 and BDNF protect CNS neurons against metabolic/excitotoxic insults
- BDNF promotes the regenerative sprouting, but not survival, of injured serotonergic axons in the adult rat brain
- Opposing roles for endogenous BDNF and NT-3 in regulating cortical dendritic growth
- Identification of a signaling pathway involved in calcium regulation of BDNF expression
- Neuronal deficits, not involving motor neurons, in mice lacking BDNF and/or NT4
- Neurotrophin expression in rat hippocampal slices: a stimulus paradigm inducing LTP in CA1 evokes increases in BDNF and NT-3 mRNAs
- BDNF enhances quantal neurotransmitter release and increases the number of docked vesicles at the active zones of hippocampal excitatory synapses
- Characteristics of BDNF-induced weight loss
- BDNF protects the neonatal brain from hypoxic-ischemic injuryin vivo via the ERK pathway
- BDNF enhances the differentiation but not the survival of CNS stem cell-derived neuronal precursors
- Potentiation of developing neuromuscular synapses by the neurotrophins NT-3 and BDNF
- Synapsins as mediators of BDNF-enhanced neurotransmitter release
- Inhibition of GABAA synaptic responses by brain-derived neurotrophic factor (BDNF) in rat hippocampus
- Impairments in high-frequency transmission, synaptic vesicle docking, and synaptic protein distribution in the hippocampus of BDNF knockout mice
- Exercise-induced regulation of brain-derived neurotrophic factor (BDNF) transcripts in the rat hippocampus
- Electrical stimulation accelerates and increases expression of BDNF and trkB mRNA in regenerating rat femoral motoneurons
- BDNF protein measured by a novel enzyme immunoassay in normal brain and after seizure: partial disagreement with mRNA levels
- BDNF has opposite effects on the quantal amplitude of pyramidal neuron and interneuron excitatory synapses
- BDNF and full-length and truncated TrkB expression in Alzheimer disease. Implications in therapeutic strategies
- BDNF and NT-415 enhance glutamatergic synaptic transmission in cultured hippoeampal neurones
- Obstructed axonal transport of BDNF and its receptor TrkB in experimental glaucoma
- BDNF and epilepsy: too much of a good thing?
- Permeability at the blood-brain and blood-nerve barriers of the neurotrophic factors: NGF, CNTF, NT-3, BDNF
- Endogenous BDNF is required for myelination and regeneration of injured sciatic nerve in rodents
- BDNF and NT-4/5 prevent atrophy of rat rubrospinal neurons after cervical axotomy, stimulate GAP-43 and Tα1-tubulin mRNA expression, and promote axonal …
- BDNF-induced TrkB activation down-regulates the K+–Cl− cotransporter KCC2 and impairs neuronal Cl− extrusion
- Intraventricular administration of BDNF increases the number of newly generated neurons in the adult olfactory bulb
- The induction of LTP increases BDNF and NGF mRNA but decreases NT-3 mRNA in the dentate gyrus.
- BDNF–triggered events in the rat hippocampus are required for both short‐and long‐term memory formation
- Differential regulation by exercise of BDNF and NT‐3 in rat spinal cord and skeletal muscle
- Rapid induction of BDNF expression in the hippocampus during immobilization stress challenge in adult rats
- Transplants of fibroblasts genetically modified to express BDNF promote regeneration of adult rat rubrospinal axons and recovery of forelimb function
- Inhibition of ocular dominance column formation by infusion of NT-4/5 or BDNF
- BDNF regulates spontaneous correlated activity at early developmental stages by increasing synaptogenesis and expression of the K+/Cl-co-transporter KCC2
- Corticosterone effects on BDNF expression in the hippocampus implications for memory formation
- Some forms of cAMP-mediated long-lasting potentiation are associated with release of BDNF and nuclear translocation of phospho-MAP kinase
- Nerve growth factors (NGF, BDNF) enhance axonal regeneration but are not required for survival of adult sensory neurons
- BDNF acutely increases tyrosine phosphorylation of the NMDA receptor subunit 2B in cortical and hippocampal postsynaptic densities
- Downregulation of BDNF mRNA in the hippocampal dentate gyrus after re-exposure to cues previously associated with footshock
- Downregulation of BDNF mRNA and protein in the rat hippocampus by corticosterone
- BDNF release from single cells elicits local dendritic growth in nearby neurons
- Overlapping and distinct actions of the neurotrophins BDNF, NT-3, and NT-4/5 on cultured dopaminergic and GABAergic neurons of the ventral mesencephalon
- Early maternal deprivation reduces the expression of BDNF and NMDA receptor subunits in rat hippocampus
- Presynaptic BDNF required for a presynaptic but not postsynaptic component of LTP at hippocampal CA1-CA3 synapses
- Visualizing synapse formation in arborizing optic axons in vivo: dynamics and modulation by BDNF
- Induction of TrkB by retinoic acid mediates biologic responsiveness to BDNF and differentiation of human neuroblastoma cells
- Destabilization of cortical dendrites and spines by BDNF
- A combination of BDNF and NT-3 promotes supraspinal axonal regeneration into Schwann cell grafts in adult rat thoracic spinal cord
- Abnormal cerebellar development and foliation in BDNF−/− mice reveals a role for neurotrophins in CNS patterning
- Bi-phasic change in BDNF gene expression following antidepressant drug treatment
- Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood− brain barrier in vivo using vector-mediated peptide drug delivery
- Sequence variants of the brain-derived neurotrophic factor (BDNF) gene are strongly associated with obsessive-compulsive disorder
- BDNF‐mediated signal transduction is modulated by GSK3β and mood stabilizing agents
- A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF
- Synaptic innervation density is regulated by neuron-derived BDNF
- BDNF stimulates migration of cerebellar granule cells
- BDNF mediates the effects of testosterone on the survival of new neurons in an adult brain
- Glatiramer acetate‐specific T‐helper 1‐and 2‐type cell lines produce BDNF: implications for multiple sclerosis therapy
- Arrest of motor neuron disease in wobbler mice cotreated with CNTF and BDNF
- Miniature synaptic transmission and BDNF modulate dendritic spine growth and form in rat CA1 neurones
- Schwann cells genetically modified to secrete human BDNF promote enhanced axonal regrowth across transected adult rat spinal cord
- Expression of BDNF and trkB as a function of age and cognitive performance
- BDNF blocks caspase-3 activation in neonatal hypoxia–ischemia
- BDNF: a neuromodulator in nociceptive pathways?
- BDNF overexpression increases dendrite complexity in hippocampal dentate gyrus
- A role for BDNF in the late-phase of hippocampal long-term potentiation
- Suppressed epileptogenesis in BDNF mutant mice
- Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats
- The NeurotroDhins BDNF, NT‐3 and NT‐4/5 Promote Survival and Morphological and Biochemical Differentiation of Striatal Neurons In Vitro
- Regional specificity of alterations in NGF, BDNF and NT-3 levels in Alzheimer’s disease.
- Association between the BDNF 196 A/G polymorphism and sporadic Alzheimer’s disease
- Activity-dependent dendritic targeting of BDNF and TrkB mRNAs in hippocampal neurons
- A BDNF coding variant is associated with the NEO personality inventory domain neuroticism, a risk factor for depression
- A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer’s disease
- Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection
- BDNF prevents and reverses adult rat motor neuron degeneration and induces axonal outgrowth
- Nitric oxide acts in a positive feedback loop with BDNF to regulate neural progenitor cell proliferation and differentiation in the mammalian brain
- Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice
- BDNF reduces miniature inhibitory postsynaptic currents by rapid downregulation of GABAA receptor surface expression
- Transplants of fibroblasts genetically modified to express BDNF promote axonal regeneration from supraspinal neurons following chronic spinal cord injury
- Sensory but not motor neuron deficits in mice lacking NT4 and BDNF
- Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases
- Met66 in the brain-derived neurotrophic factor (BDNF) precursor is associated with anorexia nervosa restrictive type
- BDNF and NT-4/5 exert neurotrophic influences on injured adult spinal motor neurons
- Functional evidence that BDNF is an anterograde neuronal trophic factor in the CNS
- Noradrenergic and serotonergic blockade inhibits BDNF mRNA activation following exercise and antidepressant
- BDNF increases monoaminergic activity in rat brain following intracerebroventricular or intraparenchymal administration
- Phosphatidylinositol 3-kinase: a molecule mediating BDNF-dependent spatial memory formation
- GABAergic stimulation switches from enhancing to repressing BDNF expression in rat hippocampal neurons during maturation in vitro
- Intracerebral transplantation of bone marrow with BDNF after MCAo in rat
- Acute intrahippocampal infusion of BDNF induces lasting potentiation of synaptic transmission in the rat dentate gyrus
- Reduced behavioral effects of cocaine in heterozygous brain-derived neurotrophic factor (BDNF) knockout mice
- Regulation of brain-derived neurotrophic factor (BDNF) expression and release from hippocampal neurons is mediated by non-NMDA type glutamate receptors
- BDNF mRNA expression in rat hippocampus and prefrontal cortex: effects of neonatal ventral hippocampal damage and antipsychotic drugs
- Activation of a TRPC3-dependent cation current through the neurotrophin BDNF
- Quantitation of BDNF mRNA in human parietal cortex by competitive reverse transcription-polymerase chain reaction: decreased levels in Alzheimer’s disease
- BDNF and NT‐3, but not NGF, Prevent Axotomy‐induced Death of Rat Corticospinal Neurons In Vivo
- Spinal brain-derived neurotrophic factor (BDNF) produces hyperalgesia in normal mice while antisense directed against either BDNF or trkB, prevent inflammation …
- Axonal growth and fasciculation linked to differential expression of BDNF and NT3 receptors in developing cerebellar granule cells
- Signaling mechanisms mediating BDNF modulation of synaptic plasticity in the hippocampus
- Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement
- Serotonin transporter function is modulated by brain-derived neurotrophic factor (BDNF) but not nerve growth factor (NGF)
- BDNF regulates the intrinsic excitability of cortical neurons
- Cultured hippocampal neurons show responses to BDNF, NT-3, and NT-4, but not NGF
- BDNF protects against spatial memory deficits following neonatal hypoxia-ischemia
- Expression of mRNAs for neurotrophic factors (NGF, BDNF, NT-3, and GDNF) and their receptors (p75 NGFR, TrkA, TrkB, and TrkC) in the adult human peripheral …
- BDNF enhances retinal ganglion cell survival in cats with optic nerve damage
- Lipopolysaccharide causes deficits in spatial learning in the watermaze but not in BDNF expression in the rat dentate gyrus
- Serum brain-derived neurotrophic factor (BDNF) levels in schizophrenia are indistinguishable from controls
- Visual cortex is rescued from the effects of dark rearing by overexpression of BDNF
- Upregulation of BDNF mRNA expression in the barrel cortex of adult mice after sensory stimulation
- Novel roles for neurotrophins are suggested by BDNF and NT-3 mRNA expression in developing neurons
- Brain-derived neurotrophic factor (BDNF) modulates inhibitory, but not excitatory, transmission in the CA1 region of the hippocampus
- BDNF-GFP containing secretory granules are localized in the vicinity of synaptic junctions of cultured cortical neurons
- BDNF mRNA expression during postnatal development, maturation and aging of the human prefrontal cortex
- Diabetic neuropathies in brain are induced by deficiency of BDNF
- Localized synaptic potentiation by BDNF requires local protein synthesis in the developing axon
- 1, 25-Dihydroxyvitamin D3 regulates NT-3, NT-4 but not BDNF mRNA in astrocytes.
- Involvement of BDNF receptor TrkB in spatial memory formation
- BDNF‐induced survival of auditory neurons in vivo: Cessation of treatment leads to accelerated loss of survival effects
- Rapid alterations of BDNF protein levels in the rat brain after focal ischemia: evidence for increased synthesis and anterograde axonal transport
- Survival effects of BDNF and NT‐3 on axotomized rubrospinal neurons depend on the temporal pattern of neurotrophin administration
- Cholinergic regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) but not neurotrophin-3 (NT-3) mRNA levels in the developing rat …
- BDNF sensitizes the response of lamina II neurons to high threshold primary afferent inputs
- A role for BDNF in mechanosensation
- BDNF injected into the superior colliculus reduces developmental retinal ganglion cell death
- Dose-related effects of chronic antidepressants on neuroprotective proteins BDNF, Bcl-2 and Cu/Zn-SOD in rat hippocampus
- Selective binding and internalisation by truncated receptors restrict the availability of BDNF during development
- PSA‐NCAM modulates BDNF‐dependent survival and differentiation of cortical neurons
- Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury
- Brain derived neurotrophic factor (BDNF) gene variants association with age at onset and therapeutic response in schizophrenia
- Opposing roles of synaptic and extrasynaptic NMDA receptors in neuronal calcium signalling and BDNF gene regulation
- Molecular mechanisms underlying activity‐dependent regulation of BDNF expression
- Simultaneous treatment with BDNF and CNTF after peripheral nerve transection and repair enhances rate of functional recovery compared with BDNF treatment alone
- Delayed grafting of BDNF and NT-3 producing fibroblasts into the injured spinal cord stimulates sprouting, partially rescues axotomized red nucleus neurons from loss …
- Neurotrophins BDNF and NT‐3 promote axonal re‐entry into the distal host spinal cord through Schwann cell‐seeded mini‐channels
- Post-occlusion treatment with BDNF reduces infarct size in a model of permanent occlusion of the middle cerebral artery in rat
- Neurotrophism without neurotropism: BDNF promotes survival but not growth of lesioned corticospinal neurons
- Ethanol consumption and serotonin‐1A (5‐HT1A) receptor function in heterozygous BDNF (+/–) mice
- Excitatory Actions of GABA Increase BDNF Expression via a MAPK-CREB–Dependent Mechanism—A Positive Feedback Circuit in Developing Neurons
- Brain‐derived neurotrophic factor (BDNF) regulates glucose and energy metabolism in diabetic mice
- Alterations in BDNF and NT-3 mRNAs in rat hippocampus after experimental brain trauma
- Autocrine—paracrine Regulation of Hippocampal Neuron Survival by IGF‐1 and the Neurotrophins BDNF, NT‐3 and NT‐4
- Truncated trkB Receptors on Nonneuronal Cells Inhibit BDNF-Induced Neurite Outgrowthin Vitro
- Deprived of habitual running, rats downregulate BDNF and TrkB messages in the brain
- … factor (GDNF) promotes the survival of axotomized retinal ganglion cells in adult rats: Comparison to and combination with brain‐derived neurotrophic factor (BDNF)
- Point mutation in trkB causes loss of NT4-dependent neurons without major effects on diverse BDNF responses
- Brain-derived neurotrophic factor (BDNF) induces dendritic targeting of BDNF and tyrosine kinase B mRNAs in hippocampal neurons through a phosphatidylinositol-3 …
- Axotomy results in major changes in BDNF expression by dorsal root ganglion cells: BDNF expression in large trkB and trkC cells, in pericellular baskets, and in …
- Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome
- Trkl3 mediates BDNF/NT-3-dependent survival and proliferation in fibroblasts lacking the low affinity NGF receptor
- Signaling mechanisms mediating BDNF modulation of memory formation in vivo in the hippocampus
- Effects of early visual experience and diurnal rhythms on BDNF mRNA and protein levels in the visual system, hippocampus, and cerebellum
- Differential effect of short-term REM sleep deprivation on NGF and BDNF protein levels in the rat brain
- Immobilization stress rapidly modulates BDNF mRNA expression in the hypothalamus of adult male rats
- BDNF and NGF treatment in lesioned rats: effects on cholinergic function and weight gain.
- Differential effects of protein synthesis inhibition on the activity-dependent expression of BDNF transcripts: evidence for immediate-early gene responses from specific …
- BDNF is a target-derived survival factor for arterial baroreceptor and chemoafferent primary sensory neurons
- Hippocampal damage and kainic acid injection induce a rapid increase in mRNA for BDNF and NGF in the rat brain
- Rapid increase of NGF, BDNF and NT-3 mRNAs in inflamed bladder
- Intraventricular administration of BDNF increases neuropeptide expression in newborn rat brain
- Association study of the brain-derived neurotrophic factor (BDNF) gene with bipolar disorder
- BDNF up‐regulates TrkB protein and prevents the death of CA1 neurons following transient forebrain ischemia
- Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson’s disease
- BDNF and NT-3 induce intracellular Ca2+ elevation in hippocampal neurones.
- ERK5 activation of MEF2-mediated gene expression plays a critical role in BDNF-promoted survival of developing but not mature cortical neurons
- Corticosterone regulates expression of BDNF and trkB but not NT‐3 and trkC mRNA in the rat hippocampus
- Differential distribution of exogenous BDNF, NGF, and NT‐3 in the brain corresponds to the relative abundance and distribution of high‐affinity and low‐affinity …
- Correlation between hippocampal BDNF mRNA expression and memory performance in senescent rats
- Amelioration of chronic neuropathic pain after partial nerve injury by adeno-associated viral (AAV) vector-mediated over-expression of BDNF in the rat spinal …
- An AMPA receptor potentiator modulates hippocampal expression of BDNF: an in vivo study
- Increased expression of BDNF and trkB mRNA in rat facial motoneurons after axotomy
- Release of BDNF and GABA in the dorsal horn of neuropathic rats
- Cell death in regenerating populations of neurons in BDNF mutant mice
- Dopamine regulates brain-derived neurotrophic factor (BDNF) expression in cultured embryonic mouse striatal cells
- Differential regulation of hippocampal BDNF mRNA by typical and atypical antipsychotic administration
- A retrospective study of percutaneous endoscopic gastrostomy in ALS patients during the BDNF and CNTF trials
- BDNF upregulation during declarative memory formation in monkey inferior temporal cortex
- Endogenous BDNF protein is increased in adult rat hippocampus after a kainic acid induced excitotoxic insult but exogenous BDNF is not neuroprotective
- BDNF regulates reelin expression and Cajal-Retzius cell development in the cerebral cortex
- Alterations in hippocampal GAP-43, BDNF, and L1 following sustained cerebral ischemia
- Prevention of 6-hydroxydopamine-induced rotational behavior by BDNF somatic gene transfer
- Manipulations of brain 5-HT levels affect gene expression for BDNF in rat brain
- Administration of a cAMP phosphodiesterase 4 inhibitor enhances antidepressant-induction of BDNF mRNA in rat hippocampus
- The action of BDNF on GABAA currents changes from potentiating to suppressing during maturation of rat hippocampal CA1 pyramidal neurons
- BDNF modulates, but does not mediate, activity-dependent branching and remodeling of optic axon arbors in vivo
- Long-term high-frequency electro-acupuncture stimulation prevents neuronal degeneration and up-regulates BDNF mRNA in the substantia nigra and ventral …
- Brain-derived neurotrophic factor (BDNF) can prevent apoptosis of rat cerebellar granule neurons in culture
- Gating of BDNF-induced synaptic potentiation by cAMP
- Differential expression of GDNF, BDNF, and NT-3 in the aging nigrostriatal system following a neurotoxic lesion
- BDNF gene expression is reduced in the frontal cortex of dopamine transporter knockout mice
- NGF, BDNF, leptin, and mast cells in human coronary atherosclerosis and metabolic syndrome
- BDNF is needed for postnatal maturation of basal forebrain and neostriatum cholinergic neurons in vivo
- BDNF in the development of the visual system of Xenopus
- Regulation of neuropeptides in adult rat forebrain by the neurotrophins BDNF and NGF
- Lack of BDNF and TrkB signalling in the postnatal cochlea leads to a spatial reshaping of innervation along the tonotopic axis and hearing loss
- BDNF is upregulated by postnatal development and visual experience: quantitative and immunohistochemical analyses of BDNF in the rat retina
- Effects of brain-derived neurotrophic factor (BDNF) on compression-induced spinal cord injury: BDNF attenuates down-regulation of superoxide dismutase expression …
- Expression of a dominant negative TrkB receptor, T1, reveals a requirement for presynaptic signaling in BDNF-induced synaptic potentiation in cultured hippocampal …
- Regionally specific effects of BDNF on oligodendrocytes
- The neurotrophins BDNF, NT‐3 and NT‐4/5, but not NGF, up‐regulate the cholinergic phenotype of developing motor neurons
- Expression of TrkB and TrkC but not BDNF mRNA in neurochemically identified interneurons in rat visual cortex in vivo and in organotypic cultures
- Mapping the differences in the brain concentration of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) in an animal model of depression
- The mesolimbic dopaminergic pathway is more resistant than the nigrostriatal dopaminergic pathway to MPTP and MPP+ toxicity: role of BDNF gene expression
- Learning abilities, NGF and BDNF brain levels in two lines of TNF-α transgenic mice, one characterized by neurological disorders, the other phenotypically normal
- Neurotrophin-4/5 (NT-4/5) and brain-derived neurotrophic factor (BDNF) act at later stages of cerebellar granule cell differentiation
- BDNF and trkB mRNAs oscillate in rat brain during the light–dark cycle
- Knocking the NT4 gene into the BDNF locus rescues BDNF deficient mice and reveals distinct NT4 and BDNF activities
- An extended surface of binding to Trk tyrosine kinase receptors in NGF and BDNF allows the engineering of a multifunctional pan‐neurotrophin.
- Combined effects of GDNF, BDNF, and CNTF on motoneuron differentiation in vitro
- Ischemic brain damage in mice after selectively modifying BDNF or NT4 gene expression
- BDNF attenuates the effects of intrastriatal injection of 6-hydroxydopamine
- Repeated electroconvulsive shock extends the duration of enhanced gene expression for BDNF in rat brain compared with a single administration
- Exogenous BDNF, NT-3 and NT-4 differentially regulate neurite outgrowth in cultured hippocampal neurons
- Brain-derived neurotrophic factor (BDNF) prevents lesion-induced axonal die-back in young rat optic nerve
- Postsynaptic action of BDNF on GABAergic synaptic transmission in the superficial layers of the mouse superior colliculus
- BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development
- Rat retinal ganglion cells co-express brain derived neurotrophic factor (BDNF) and its receptor TrkB
- In Situ Hybridization of trkB and trkC Receptor mRNA in Rat Forebrain and Association with High‐affinity Binding of [125I]BDNF, [125I]NT‐4/5 and [125I]NT‐3
- Brain-derived neurotrophic factor (BDNF) is upregulated and associated with pain in chronic pancreatitis
- Protection of axotomized retinal ganglion cells by adenovirally delivered BDNF in vivo
- Are there differences between the secretion characteristics of NGF and BDNF? Implications for the modulatory role of neurotrophins in activity‐dependent neuronal …
- Changes in spinal GDNF, BDNF, and NT‐3 expression after transient spinal cord ischemia in the rat
- Up‐regulation of the neuronal serotoninergic phenotype in vitro: BDNF and cAMP share Trk B‐dependent mechanisms
- Expression of BDNF and NT-3 mRNA in hair cells of the organ of Corti: quantitative analysis in developing rats
- Coexpression of mRNAs for NGF, BDNF, and NT-3 in the cardiovascular system of the pre-and postnatal rat
- BDNF enhances the functional reinnervation of the striatum by grafted fetal dopamine neurons
- Regulation of BDNF expression in primary neuron culture by LY392098, a novel AMPA receptor potentiator
- BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain
- Development of normal and injury-induced gene expression of aFGF, bFGF, CNTF, BDNF, GFAP and IGF-I in the rat retina
- Effects of the neurotrophins nerve growth factor, neurotrophin‐3, and brain‐derived neurotrophic factor (BDNF) on neurite growth from adult sensory neurons in …
- Accelerated dendritic development of rat cortical pyramidal cells and interneurons after biolistic transfection with BDNF and NT4/5
- Effects of chronic exercise and imipramine on mRNA for BDNF after olfactory bulbectomy in rat
- Maternal infection regulates BDNF and NGF expression in fetal and neonatal brain and maternal–fetal unit of the rat
- Selegiline and desmethylselegiline stimulate NGF, BDNF, and GDNF synthesis in cultured mouse astrocytes
- BDNF up‐regulates evoked GABAergic transmission in developing hippocampus by potentiating presynaptic N‐ and P/Q‐type Ca2+ channels signalling
- Degeneration of vestibular neurons in late embryogenesis of both heterozygous and homozygous BDNF null mutant mice
- Association between the BDNF gene and schizophrenia
- A combination of CNTF and BDNF rescues rd photoreceptors but changes rod differentiation in the presence of RPE in retinal explants
- GDNF and BDNF alter the expression of neuronal NOS, c-Jun, and p75 and prevent motoneuron death following spinal root avulsion in adult rats
- Grafts of BDNF-producing fibroblasts rescue axotomized rubrospinal neurons and prevent their atrophy
- Control of early cell death by BDNF in the chick retina
- GDNF but not BDNF is increased in cerebrospinal fluid in amyotrophic lateral sclerosis
- Changes in BDNF-immunoreactive structures in the hippocampal formation of the aged macaque monkey
- Thyroid hormone regulation of NGF, NT-3 and BDNF RNA in the adult rat brain
- Decreased BDNF signalling in transgenic mice reduces epileptogenesis
- Signalling pathways involved in the short-term potentiation of dopamine release by BDNF
- Lingual deficits in BDNF and NT3 mutant mice leading to gustatory and somatosensory disturbances, respectively
- Dynamic patterns of BDNF expression in injured sensory neurons: differential modulation by NGF and NT‐3
- Dopaminergic stimulation up-regulates the in vivo expression of brain-derived neurotrophic factor (BDNF) in the striatum
- Beta-amyloid and brain-derived neurotrophic factor, BDNF, up-regulate the expression of glutamate transporter GLT-1/EAAT2 via different signaling pathways utilizing …
- Delayed transplantation of fibroblasts genetically modified to secrete BDNF and NT-3 into a spinal cord injury site is associated with limited recovery of function
- Ngf, BDNF, Nt3, Nt4 and Gdnf in Tooth Development
- Animal model of dementia induced by entorhinal synaptic damage and partial restoration of cognitive deficits by BDNF and carnitine
- Alterations in BDNF and synapsin I within the occipital cortex and hippocampus after mild traumatic brain injury in the developing rat: reflections of injury-induced …
- A caged Ab reveals an immediate/instructive effect of BDNF during hippocampal synaptic potentiation
- Blockade of NR2B-containing NMDA receptors prevents BDNF enhancement of glutamatergic transmission in hippocampal neurons
- VIP and PACAP potentiate the action of glutamate on BDNF expression in mouse cortical neurones
- NT‐3, but not BDNF, prevents atrophy and death of axotomized spinal cord projection neurons
- Autocrine BDNF secretion enhances the survival and serotonergic differentiation of raphe neuronal precursor cells grafted into the adult rat CNS
- NGF and BDNF are differentially modulated by visual experience in the developing geniculocortical pathway
- Brain-derived-neurotrophic-factor (BDNF) stress response in rats bred for learned helplessness
- The neurotrophins NT-4/5 and BDNF augment serotonin, dopamine, and GABAergic systems during behaviorally effective infusions to the substantia nigra
- Alterations in size, number, and morphology of gustatory papillae and taste buds in BDNF null mutant mice demonstrate neural dependence of developing taste …
- Effects of BDNF infusion on the regulation of TrkB protein and message in adult rat brain
- Mismatch between BDNF mRNA and protein expression in the developing visual cortex: the role of visual experience
- Chimeric molecules with multiple neurotrophic activities reveal structural elements determining the specificities of NGF and BDNF.
- Patterned expression of BDNF and NT-3 in the retina and anterior segment of the developing mammalian eye
- BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons
- Embryonic precursor cells that express Trk receptors: induction of different cell fates by NGF, BDNF, NT-3, and CNTF
- Co‐localization of brain‐derived neurotrophic factor (BDNF) and wild‐type huntingtin in normal and quinolinic acid‐lesioned rat brain
- Cortical spreading depression induces long-term alterations of BDNF levels in cortex and hippocampus distinct from lesion effects: implications for ischemic tolerance
- Brain-derived neurotrophic factor (BDNF) in stress and affective disorders
- The regrowth of axons within tissue defects in the CNS is promoted by implanted hydrogel matrices that contain BDNF and CNTF producing fibroblasts
- BDNF prevents NO mediated glutamate cytotoxicity in cultured cortical neurons
- Rescue of axotomized retinal ganglion cells by BDNF gene electroporation in adult rats
- Differences in survival‐promoting effects and intracellular signaling properties of BDNF and IGF‐1 in cultured cerebral cortical neurons
- Defective HSV-1 vector expressing BDNF in auditory ganglia elicits neurite outgrowth: model for treatment of neuron loss following cochlear degeneration
- A prospective, randomized, placebo‐controlled evaluation of corticoneuronal response to intrathecal BDNF therapy in ALS using magnetic resonance spectroscopy …
- Adenoviral gene transfer of GDNF, BDNF and TGFβ2, but not CNTF, cardiotrophin‐1 or IGF1, protects injured adult motoneurons after facial nerve avulsion
- Truncated TrkB mediates the endocytosis and release of BDNF and neurotrophin-4/5 by rat astrocytes and schwann cells in vitro
- Modulation of DOI-induced increases in cortical BDNF expression by group II mGlu receptors
- Evaluation of nigrostriatal dopaminergic function in adult+/+ and+/− BDNF mutant mice
- BDNF synthesis in spiral ganglion neurons is constitutive and CREB-dependent
- BDNF mRNA expression in the developing rat brain following kainic acid-induced seizure activity
- Effect of BDNF on dopaminergic, serotonergic, and GABAergic neurons in cultures of human fetal ventral mesencephalon
- Brain-derived neurotrophic factor (BDNF) Val66Met polymorphisms in Parkinson’s disease and age of onset
- Granule cell mRNA levels for BDNF, NGF, and NT-3 correlate with neuron losses or supragranular mossy fiber sprouting in the chronically damaged and epileptic …
- A polymorphism of the brain-derived neurotrophic factor (BDNF) is associated with Alzheimer’s disease in patients lacking the Apolipoprotein E ε4 allele
- Neurotrophins induce BDNF expression through the glutamate receptor pathway in neocortical neurons
- Grafts of fibroblasts genetically modified to secrete NGF, BDNF, NT-3, or basic FGF elicit differential responses in the adult spinal cord
- BDNF diminishes caspase-2 but not c-Jun immunoreactivity of neurons in retinal ganglion cell layer after transient ischemia
- Synergistic but transient rescue effects of BDNF and GDNF on axotomized neonatal motoneurons
- Analysis of effects and pharmacokinetics of subcutaneously administered BDNF
- BDNF but not NT-4 is required for normal flexion reflex plasticity and function
- The Cellular Patterns of BDNF andtrkBExpression Suggest Multiple Roles for BDNF duringXenopusVisual System Development
- Grafting of encapsulated BDNF-producing fibroblasts into the injured spinal cord without immune suppression in adult rats
- Circadian variation in BDNF mRNA expression in the rat hippocampus
- BDNF modulates sensory neuron synaptic activity by a facilitation of GABA transmission in the dorsal horn
- Ceramide activates microglia to enhance the production/secretion of brain‐derived neurotrophic factor (BDNF) without induction of deleterious factors in vitro
- Synergistic effects of BDNF and NT‐3 on postnatal spiral ganglion neurons
- Role of the neurotrophic factors BDNF and NGF in the commitment of pluripotent neural crest cells
- Induction of brain-derived neurotrophic factor (BDNF) and the receptor trk B mRNA following middle cerebral artery occlusion in rat
- FGF-2, NGF and IGF-1, but not BDNF, utilize a nitric oxide pathway to signal neurotrophic and neuroprotective effects against alcohol toxicity in cerebellar granule cell …
- Lesion-induced increase of BDNF is greater in the striatum of young versus old rat brain
- Hippocampal BDNF mRNA shows a diurnal regulation, primarily in the exon III transcript
- Treatment with genetically engineered fibroblasts producing NGF or BDNF can accelerate recovery from traumatic spinal cord injury in the adult rat.
- … antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin …
- Increased BDNF and trk‐B mRNA expression in cortical and limbic regions following formation of a social recognition memory
- BDNF attenuates hippocampal LTD via activation of phospholipase C: implications for a vertical shift in the frequency–response curve of synaptic plasticity
- Intact spatial learning and memory in transgenic mice with reduced BDNF
- Atrophy but not death of adult septal cholinergic neurons after ablation of target capacity to produce mRNAs for NGF, BDNF, and NT3
- Transient changes of brain-derived neurotrophic factor (BDNF) mRNA expression in hippocampus during moderate ischemia induced by chronic bilateral common …
- BDNF and trkB mRNA expression in the hippocampal formation of aging rats
- BDNF heightens the sensitivity of motor neurons to excitotoxic insults through activation of TrkB
- Serotonergic cells of the rat raphe nuclei express mRNA of tyrosine kinase B (trkB), the high-affinity receptor for brain derived neurotrophic factor (BDNF)
- Immobilization stress rapidly and differentially modulates BDNF and TrkB mRNA expression in the pituitary gland of adult male rats
- Glucocorticoids depress activity-dependent expression of BDNF mRNA in hippocampal neurones.
- Effects of biologically delivered NGF, BDNF and bFGF on striatal excitotoxic lesions.
- BDNF produces analgesia in the formalin test and modifies neuropeptide levels in rat brain and spinal cord areas associated with nociception
- Neurotrophic effects of BDNF and CNTF, alone and in combination, on postnatal day 5 rat acoustic ganglion neurons
- Pharmacokinetics of intrathecally applied BDNF and effects on spinal motoneurons
- Determinants of BDNF-induced hippocampal synaptic plasticity: role of the Trk B receptor and the kinetics of neurotrophin delivery.
- NGF, BDNF and NT-5, but not NT-3 protect against MPP+ toxicity and oxidative stress in neonatal animals
- Expression of the BDNF gene in the developing visual system of the chick
- Tool-use learning induces BDNF expression in a selective portion of monkey anterior parietal cortex
- BDNF and NT‐4 differentially modulate neurite outgrowth in developing retinal ganglion cells
- … MR determined apparent diffusion coefficients correlate with motor recovery mediated by intraspinal transplants of fibroblasts genetically modified to express BDNF
- Effects of dopamine agonists bromocriptine, pergolide, cabergoline, and SKF-38393 on GDNF, NGF, and BDNF synthesis in cultured mouse astrocytes
- BDNF induces translocation of initiation factor 4E to mRNA granules: evidence for a role of synaptic microfilaments and integrins
- Neurotrophic factor regulation of developing avian oculomotor neurons: differential effects of BDNF and GDNF
- Effect of NT‐4 and BDNF delivery to damaged sciatic nerves on phenotypic recovery of fast and slow muscles fibres
- A possible role for BDNF, NT-4 and TrkB in the spinal cord and muscle of rat subjected to mechanical overload, bupivacaine injection and axotomy
- ECS-Induced mossy fiber sprouting and BDNF expression are attenuated by ketamine pretreatment
- Differential effects of BDNF, ADNF9, and TNFα on levels of NMDA receptor subunits, calcium homeostasis, and neuronal vulnerability to excitotoxicity
- BDNF protection of auditory neurons from cisplatin involves changes in intracellular levels of both reactive oxygen species and glutathione
- Epithelial overexpression of BDNF or NT4 disrupts targeting of taste neurons that innervate the anterior tongue
- LIF is more potent than BDNF in promoting neurite outgrowth of mammalian auditory neurons in vitro
- Expression of mRNAs for neurotrophins (NGF, BDNF, and NT-3) and their receptors (p75 NGFR, trk, trkB, and trkC) in human peripheral neuropathies
- The human BDNF gene maps between FSHB and HVBS1 at the boundary of 11p13–p14
- BDNF, NT‐3 and NGF induce distinct new Ca2+ channel synthesis in developing hippocampal neurons
- Differential effects of NGF and BDNF on voltage-gated calcium currents in embryonic basal forebrain neurons
- Effects of neurotransplants and BDNF on the survival and regeneration of injured adult spinal motoneurons
- Topically applied betaxolol attenuates ischaemia-induced effects to the rat retina and stimulates BDNF mRNA
- Distribution of BDNF, NT-3 and NT-4 in the developing auditory brainstem
- Brain insults in rats induce increased expression of the BDNF gene through differential use of multiple promoters
- Corticosterone effects on BDNF mRNA expression in the rat hippocampus during morris water maze training
- Alterations in nigrostriatal dopaminergic function within BDNF mutant mice
- Expression of specific tubulin isotypes increases during regeneration of injured CNS neurons, but not after the application of brain-derived neurotrophic factor (BDNF)
- Retinal ganglion cell survival is promoted by genetically modified astrocytes designed to secrete brain-derived neurotrophic factor (BDNF)
- NT-3 regulates BDNF-induced modulation of synaptic transmission in cultured hippocampal neurons
- Rapid increase of BDNF mRNA levels in cortical neurons following spreading depression: regulation by glutamatergic mechanisms independent of seizure activity
- Rapid and opposite effects of BDNF and NGF on the functional organization of the adult cortex in vivo
- BDNF enhances neuronal growth and synaptic activity in hippocampal cell cultures
- Cellular hybridization for BDNF. trk B, and NGF mRNAs and BDNF-immunoreactivity in rat forebrain after pilocarpine-induced status epilepticus
- Retrograde transport of brain‐derived neurotrophic factor (BDNF) following infusion in neo‐and limbic cortex in rat: relationship to BDNF mRNA expressing neurons
- Expression of neurotrophins BDNF and NT-3, and their receptors in rat brain after administration of antipsychotic and psychotrophic agents
- REST4-mediated modulation of REST/NRSF-silencing function during BDNF gene promoter activation
- Striatal dopamine output is compromised within+/− BDNF mice
- Transplantation of genetically modified fibroblasts expressing BDNF in adult rats with a subtotal hemisection improves specific motor and sensory functions
- Alterations in BDNF and trkB mRNA levels in the cerebral cortex following experimental brain trauma in rats
- BDNF, and full length and truncated TrkB expression in the hippocampus of the rat following kainic acid excitotoxic damage. Evidence of complex time-dependent and …
- Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells
- Early BDNF, NT-3, and NT-4 signaling events
- Dynamic regulation of BDNF and NT‐3 expression during visual system development
- Down-regulation of BDNF mRNA, with no effect on trkB or glucocorticoid receptor mRNAs, in the porcine hippocampus after acute dexamethasone treatment
- GABA–glutamate interaction in the control of BDNF expression in hypothalamic neurons
- Nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF) and low-affinity nerve growth factor receptor (LNGFR) mRNA levels in cultured rat Schwann cells; …
- NMDA-stimulated expression of BDNF mRNA in cultured cerebellar granule neurones.
- trkB-receptor activation contributes to the kainate-induced increase in BDNF mRNA synthesis
- Differential effects of GDNF and BDNF on cultured ventral mesencephalic neurons
- Association of partial epilepsy with brain-derived neurotrophic factor (BDNF) gene polymorphisms
- Agonistic encounters in aged male mouse potentiate the expression of endogenous brain NGF and BDNF: possible implication for brain progenitor cells’ activation
- Interaction of BDNF and testosterone in the regulation of adult perineal motoneurons
- TrkB mediates BDNF-induced potentiation of neuronal necrosis in cortical culture
- Intracerebroventricular administration of an endothelin ETB receptor agonist increases expressions of GDNF and BDNF in rat brain
- EGF and NGF injected into the brain of old mice enhance BDNF and ChAT in proliferating subventricular zone
- Heritability of BDNF alleles and their effect on brain morphology in schizophrenia
- Acute modulation of synaptic transmission to motoneurons by BDNF in the neonatal rat spinal cord
- Glucocorticoids modulate BDNF mRNA expression in the rat hippocampus after traumatic brain injury
- BDNF as an anterophin; a novel neurotrophic relationship between brain neurons
- Human cerebral endothelial cells are a potential source for bioactive BDNF
- BDNF, but not NT-3, promotes long-term survival of axotomized adult rat corticospinal neurons in vivo
- Protective effect against ischemia and light damage of iris pigment epithelial cells transfected with the BDNF gene
- A controlled trial of recombinant methionyl human BDNF in ALS
- Differential Effects of NGF and BDNF on Axotomy-Induced Changes in GABAA-Receptor-Mediated Conductance and Sodium Currents in Cutaneous Afferent …
- Effects of BDNF and NT-3 on hair cell survival in guinea pig cochlea damaged by kanamycin treatment
- Does BDNF have pre-or postsynaptic targets?
- Effects of BDNF and NT-3 on development of Ia/motoneuron functional connectivity in neonatal rats
- BDNF is required for the normal development of taste neurons in vivo
- Brain‐derived neurotrophic factor‐transduced fibroblasts: Production of BDNF and effects of grafting to the adult rat brain
- Protective effects of BDNF and NT-3 but not PDGF against hypoglycemic injury to cultured striatal neurons
- Signal transduction events mediated by the BDNF receptor gp 145trkB in primary hippocampal pyramidal cell culture
- A discrete domain of the human TrkB receptor defines the binding sites for BDNF and NT-4
- Modulation of HERG current and herg gene expression during retinoic acid treatment of human neuroblastoma cells: Potentiating effects of BDNF
- Co-infusion with a TrkB-Fc receptor body carrier enhances BDNF distribution in the adult rat brain
- Induction of functional and morphological expression of neuropeptide Y (NPY) in cortical cultures by brain-derived neurotrophic factor (BDNF): evidence for a …
- Simultaneous GDNF and BDNF application leads to increased motoneuron survival and improved functional outcome in an experimental model for obstetric brachial …
- BDNF increases the number of axotomized rat retinal ganglion cells expressing GAP-43, L1, and TAG-1 mRNA—a supportive role for nitric oxide?
- BDNF or IGF-I potentiates free radical-mediated injury in cortical cell cultures.
- Developmentally regulated expression of HDNF/NT‐3 mRNA in rat spinal cord motoneurons and expression of BDNF mRNA in embryonic dorsal root ganglion
- No linkage or linkage disequilibrium between brain-derived neurotrophic factor (BDNF) dinucleotide repeat polymorphism and schizophrenia in Irish families
- Expression of brain-derived neurotrophic factor (BDNF) and inducible nitric oxide synthase (iNOS) in rat astrocyte cultures treated with Levetiracetam
- Memory consolidation in day-old chicks requires BDNF but not NGF or NT-3; an antisense study
- Fibroblasts genetically modified to produce BDNF support regrowth of chronically injured serotonergic axons
- BDNF atelocollagen mini-pellet accelerates facial nerve regeneration
- Rat fetal ventral mesencephalon grown as solid tissue cultures: influence of culture time and BDNF treatment on dopamine neuron survival and function
- Photochemical stroke and brain-derived neurotrophic factor (BDNF) mRNA expression.
- BDNF and NGF afford in vitro neuroprotection against ethanol combined with acute ischemia and chronic hypoglycemia
- Expression and binding characteristics of the BDNF receptor chick trkB
- Effects of BDNF and NT‐4/5 on Striatonigral Neuropeptides or Nigral GABA Neurons In Vivo
- BDNF stimulates expression, activity and release of tissue‐type plasminogen activator in mouse cortical neurons
- Activation of NMDA receptors increases brain-derived neurotrophic factor (BDNF) mRNA expression in the hippocampal formation.
- Anterograde transport and trophic actions of BDNF and NT-4/5 in the developing rat visual system
- Perinatal exposure to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin alters activity-dependent expression of BDNF mRNA in the neocortex and male rat sexual behavior in …
- BDNF and NT-3 rescue sensory but not motoneurones following axotomy in the neonate.
- The anterogradely transported BDNF promotes retinal axon remodeling during eye specific segregation within the LGN
- BDNF supports mammalian chemoafferent neurons in vitro and following peripheral target removal in vivo
- BDNF regulates the expression of fragile X mental retardation protein mRNA in the hippocampus
- 5-HT 2A receptor activation leads to increased BDNF mRNA expression in C6 glioma cells
- Brain-derived neurotrophic factor (BDNF): role in neuronal development and survival.
- BDNF gene transfer to the mammalian brain using CNS-derived neural precursors
- Influence of BDNF on the expression of the dopaminergic phenotype of tissue used for brain transplants
- NMDA induces BDNF expression in the albino rat retina in vivo
- The effect of a global birth asphyxia on the ontogeny of BDNF and NGF protein expression in the juvenile brain
- Infarct tolerance accompanied enhanced BDNF-like immunoreactivity in neuronal nuclei
- Brain‐derived neurotrophic factor (BDNF) mediates bone morphogenetic protein‐2 (BMP‐2) effects on cultured striatal neurones
- Neonatal olfactory sensory deprivation decreases BDNF in the olfactory bulb of the rat
- NGF but not NT-3 or BDNF prevents the A fiber sprouting into lamina II of the spinal cord that occurs following axotomy
- The BDNF content of postnatal and adult rat brain: the effects of 6-hydroxydopamine lesions in adult brain
- Interactions of neurotrophin-3 (NT-3), brain-derived neurotrophic factor (BDNF), and the NT-3. BDNF heterodimer with the extracellular domains of the TrkB and TrkC …
- Ultrastructural localisation of intramuscular expression of BDNF mRNA by silver-gold intensified non-radioactive in situ hybridisation
- Unilateral hippocampal lesions in newborn and adult rats: effects on spatial memory and BDNF gene expression
- Involvement of VIP on BDNF-induced somatostatin gene expression in cultured fetal rat cerebral cortical cells
- The effects of intrahippocampal BDNF and NGF on spatial learning in aged Long Evans rats
- Characterization of dopaminergic midbrain neurons in a DBH: BDNF transgenic mouse
- Target‐derived BDNF (brain‐derived neurotrophic factor) is essential for the survival of developing neurons in the isthmo‐optic nucleus
- BDNF attenuates retinal cell death caused by chemically induced hypoxia in rats
- The p75 receptor is required for BDNF-induced differentiation of neural precursor cells
- Dopaminergic transmitter up-regulation of brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) synthesis in mouse astrocytes in culture
- Distinct populations of hypothalamic dopaminergic neurons exhibit differential responses to brain‐derived neurotrophic factor (BDNF) and neurotrophin‐3 (NT3)
- BDNF is involved in sympathetic sprouting in the dorsal root ganglia following peripheral nerve injury in rats
- BDNF and CNTF regulate cholinergic properties of sympathetic neurons through independent mechanisms
- Expression of BDNF and TrkB in mouse taste buds after denervation and in circumvallate papillae during development
- Soya phytoestrogens change cortical and hippocampal expression of BDNF mRNA in male rats
- DCG-IV but not other group-II metabotropic receptor agonists induces microglial BDNF mRNA expression in the rat striatum. Correlation with neuronal injury
- Lack of association between the BDNF Val66Met polymorphism and Parkinson’s disease in a Swedish population
- BDNF dependence in neuroblastoma
- BDNF‐activated Sianal Transduction in Rat Cortical Glial Cells
- BDNF attenuates functional and structural disorders in nerves of galactose-fed rats
- Purification and characterisation of a brain‐derived neurotrophic factor/neurotrophin‐3 (BDNF/NT‐3) heterodimer
- Changes in BDNF and neurotrophin receptor expression in degenerating and regenerating rat retinal ganglion cells
- The expression of trkB and p75 and the role of BDNF in the developing neuromuscular system of the chick embryo
- The control of [125I] BDNF release from striatal rat brain slices
- Neurotrophins and their receptors in the rat pituitary gland: regulation of BDNF and trk B mRNA levels by adrenal hormones
- Transient PKA activity is required for initiation but not maintenance of BDNF-mediated protection from nitric oxide-induced growth-cone collapse
- Brain-derived neurotrophic factor (BDNF) mRNA in rats with neonatal ibotenic acid lesions of the ventral hippocampus
- The morphogenesis of mouse vallate gustatory epithelium and taste buds requires BDNF-dependent taste neurons
- Retinoic acid induces BDNF responsiveness of sympathetic neurons by alteration of Trk neurotrophin receptor expression
- BDNF and NT4/5 promote survival and neurite outgrowth of pontocerebellar mossy fiber neurons
- Lingual BDNF and NT‐3 mRNA expression patterns and their relation to innervation in the human tongue: Similarities and differences compared with rodents
- Coordination of early neural tube development by BDNF/trkB
- BDNF potentiates spontaneous Ca2+ oscillations in cultured hippocampal neurons
- Early induction of mRNA for calbindin-D28k and BDNF but not NT-3 in rat hippocampus after kainic acid treatment
- Suppressed kindling epileptogenesis and perturbed BDNF and TrkB gene regulation in NT-3 mutant mice
- Brain-derived neurotrophic factor (BDNF) protects cultured rat cerebellar granule neurons against glucose deprivation-induced apoptosis
- Facilitation of AVP (4–8) on gene expression of BDNF and NGF in rat brain
- BDNF makes cultured dentate granule cells more resistant to hypoglycaemic damage.
- BDNF protection of basal forebrain cholinergic neurons after axotomy: complete protection of p75NGFR-positive cells.
- Regulation of NGF, BDNF and LNGFR gene expression in ROS 172.8 cells
- Neurotrophin dependence mediated by p75 NTR: contrast between rescue by BDNF and NGF
- Expression of mRNAs encoding BDNF and its receptor in adult rat hypothalamus
- Cell death in the inner nuclear layer of the retina is modulated by BDNF
- BDNF induces glutamate release in cerebrocortical nerve terminals and in cortical astrocytes
- BDNF and NT-4, but not NT-3, promote development of inhibitory synapses in the absence of neuronal activity
- Impaired eye-blink conditioning in waggler, a mutant mouse with cerebellar BDNF deficiency
- MK801 induces immediate-early gene proteins and BDNF mRNA in rat cerebrocortical neurones.
- Regulation of BDNF promoters in the rat hippocampus
- Opposing effects of morphine and the neurotrophins, NT-3, NT-4, and BDNF, on locus coeruleus neurons in vitro
- The depolarisation-induced release of [125I] BDNF from brain tissue
- Early postnatal ethanol exposure selectively decreases BDNF and truncated TrkB-T2 receptor mRNA expression in the rat cerebellum
- Peptide immunoreactivity in aged rat cortex and hippocampus as a function of memory and BDNF infusion
- Spatially restricted actions of BDNF
- Alterations in the Neurotrophic Factors BDNF, GDNF and CNTF in the Regenerating Olfactory Systema
- Paracrine interactions of BDNF involving NGF-dependent embryonic sensory neurons
- Up-and down-regulation of BDNF mRNA in distinct subgroups of rat sensory neurons after axotomy
- … of serotonergic neurons following spinal hemisection restores spinal serotonin, downregulates serotonin transporter, and increases BDNF tissue content in rat
- Organization, sequence and functional analysis of a mouse BDNF promoter
- BDNF increases the expression of neuropeptide Y mRNA and promotes differentiation/maturation of neuropeptide Y-positive cultured cortical neurons from embryonic …
- Neuronal precursors of the adult rat subependymal zone persist into senescence, with no decline in spatial extent or response to BDNF
- Influence of thyroid hormone on 5-HT1A and 5-HT2A receptor-mediated regulation of hippocampal BDNF mRNA expression
- MEK inhibitors block BDNF-dependent and-independent expression of GABAA receptor subunit mRNAs in cultured mouse cerebellar granule neurons
- Immunohistochemical localization of BDNF‐, TrkB‐and TrkA‐like proteins in the teleost lateral line system
- Sodium chloride enhances the storage and conformational stability of BDNF and PEG-BDNF
- Enhancement of BDNF and activated-ERK immunoreactivity in spinal motor neurons after peripheral administration of BDNF
- Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells
- Exercise increases mRNA levels for adhesion molecules N-CAM and L1 correlating with BDNF response
- NGF and BDNF increase the immunoreactivity of vesicular acetylcholine transporter in cultured neurons from the embryonic rat septum
- BDNF-mediated rescue of axotomized motor neurones decreases with increasing dose.
- Experimental changes in BDNF-and NT-3-like immunoreactivities in the spinal cord following its transection
- BDNF abolishes the survival effect of NT‐3 in axotomized clarke neurons of adult rats
- The survival of NGF-dependent but not BDNF-dependent cranial sensory neurons is promoted by several different neurotrophins early in their development
- Effects of combined BDNF and GDNF treatment on cultured dopaminergic midbrain neurons
- BDNF Gene Can Be Activated by Ca2+ Signals without Involvement ofde NovoAP-1 Synthesis
- Developmental changes in BDNF protein levels in the hamster retina and superior colliculus
- Identification of potential compounds promoting BDNF production in nigral dopaminergic neurons: clinical implication in Parkinson’s disease
- Repetitive firing deficits and reduced sodium current density in retinal ganglion cells developing in the absence of BDNF
- BDNF-induced potentiation of spontaneous twitching in innervated myocytes requires calcium release from intracellular stores
- A paracrine effect for neuron-derived BDNF in development of dorsal root ganglia: stimulation of Schwann cell myelin protein expression by glial cells
- A novel BDNF gene promoter directs expression to skeletal muscle
- Timing and Regulation of trkB and BDNF mRNA Expression in Placode‐derived Sensory Neurons and their Targets
- Implanted BDNF-producing fibroblasts prevent neurotoxin-induced serotonergic denervation in the rat striatum
- 6-Hydroxydopamine lesions reduce BDNF mRNA levels in adult rat brain substantia nigra.
- BDNF and NT-3 widen the scope of neurotrophin activity: pharmacological implications
- In vivo activation and in situ BDNF-stimulated nuclear translocation of mitogen-activated/extracellular signal-regulated protein kinase is inhibited by ethanol in the …
- BDNF
- Transcript-specific effects of adrenalectomy on seizure-induced BDNF expression in rat hippocampus
- BDNF and TrkB co-localize in CA1 neurons resistant to transient forebrain ischemia in the adult gerbil
- … permeability disturbances, edema formation and cell injury in the spinal cord following trauma: an experimental study using topical application of BDNF and IGF-1 in …
- Functional recovery of transected nerves treated with systemic BDNF and CNTF
- The effect of NGF, BDNF and bFGF on expression of galanin in cultured rat dorsal root ganglia
- 5-Azacytidine and BDNF enhance the maturation of neurons derived from EGF-generated neural stem cells
- Spatiotemporal expression of BDNF in the hippocampus induced by the continuous intracerebroventricular infusion of β-amyloid in rats
- A role for BDNF in early postnatal rat vestibular epithelia maturation: implication of supporting cells
- BDNF and trkB mRNA expression in the rat hippocampus following entorhinal cortex lesions.
- Upregulation of BDNF mRNA and trkB mRNA in the nigrostriatal system and in the lesion site following unilateral transection of the medial forebrain bundle
- Retinoic acid increases BDNF-dependent regeneration of chick retinal ganglion cells in vitro
- Differential influence of BDNF and NT3 on the expression of calcium binding proteins and neuropeptide Y in vivo
- Short increase of BDNF messenger RNA triggers kainic acid-induced neuronal hypertrophy in adult mice
- Effect of the novel sigma1 receptor ligand and putative atypical antipsychotic E-5842 on BDNF mRNA expression in the rat brain
- Survival factors promote BDNF protein expression in mesencephalic dopaminergic neurons
- Relationship between BDNF-and trk-expressing neurones in rat dorsal root ganglion: an analysis by in situ hybridization
- Reciprocal up-and down-regulation of BDNF mRNA in tetanus toxin-induced epileptic focus and inhibitory surround in cerebral cortex.
- Does BDNF contribute to temporal lobe epilepsy?
- BDNF-dependent enhancement of exocytosis in cultured cortical neurons requires translation but not transcription
- Regulation of brain-derived neurotrophic factor (BDNF) expression following antibiotic treatment of experimental bacterial meningitis
- … convertase PC1 is induced in the transected sciatic nerve and is present in cultured Schwann cells: comparison with PC5, furin and PC7, implication in pro-BDNF …
- Pattern of trkB protein-like immunoreactivity in vivo and the in vitro effects of brain-derived neurotrophic factor (BDNF) on developing cochlear and vestibular neurons
- NGF, BDNF and NT-3 play unique roles in the in vitro development and patterning of innervation of the mammalian inner ear
- Different patterns of induction of FGF‐2, FGF‐1 and BDNF mRNAs during kindling epileptogenesis in the rat
- BDNF regulation of androgen receptor expression in axotomized SNB motoneurons of adult male rats
- BDNF and NT3 extend the critical period for developmental climbing fibre plasticity
- Distribution of BDNF, NT-3, trkB and trkC in the developing retino-tectal system of the pigeon (Columba livia)
- The neurotrophins BDNF, NT-3 and-4, but not NGF, TGF-β1 and GDNF, increase the number of NADPH-diaphorase-reactive neurons in rat spinal cord cultures
- Coactivation of secretogranin-II and BDNF genes mediated by calcium signals in mouse cerebellar granule cells
- BDNF/trkB signaling in the developmental sculpting of visual connections
- Distinct neurotrophic responses of axotomized motor neurons to BDNF and CNTF in adult rats.
- Influence of time in culture and BDNF pretreatment on survival and function of grafted embryonic rat ventral mesencephalon in the 6-OHDA rat model of Parkinson’s …
- Unilateral vestibular deafferentation induces brain-derived neurotrophic factor (BDNF) protein expression in the guinea pig lateral but not medial vestibular nuclei
- Comparison of the effects of HGF, BDNF, CT‐1, CNTF, and the branchial arches on the growth of embryonic cranial motor neurons
- NGF/BDNF chimeric proteins: analysis of neurotrophin specificity by homolog-scanning mutagenesis
- Neurotrophic factors BDNF and GDNF protect embryonic chick spinal cord motoneurons from ethanol neurotoxicity in vivo
- Optimal effectiveness of BDNF for fetal nigral transplants coincides with the ontogenic appearance of BDNF in the striatum
- Activation of BDNF mRNA and protein after seizures in hyperbaric oxygen: implications for sensitization to seizures in re-exposures
- BDNF overexpression induces differential increases among subsets of sympathetic innervation in murine back skin
- BDNF and NT-3 modulate expression and threonine phosphorylation of microtubule-associated protein 2 analogues, and alter their distribution in the developing rat …
- Developmental regulation of BDNF and NT-3 expression by quinolinic acid in the striatum and its main connections
- Down-regulation of phosphatidylinositol response to BDNF and NT-3 in cultures of cortical neurons
- Decrease in the levels of NGF and BDNF in brains of mice fed a tryptophan-deficient diet
- BDNF increases the early expression of TRH mRNA in fetal TrkB+ hypothalamic neurons in primary culture
- BDNF restores the expression of Jun and Fos inducible transcription factors in the rat brain following repetitive electroconvulsive seizures
- Immunohistochemical analysis of the neurotrophins BDNF and NT-3 and their receptors trk B, trk C, and p75 in the developing chick retina
- Immunological relationships of NGF, BDNF, and NT-3: recognition and functional inhibition by antibodies to NGF
- Developing vestibular ganglion neurons switch trophic sensitivity from BDNF to GDNF after target innervation
- Attenuation of cell death mediated by membrane depolarization different from that by exogenous BDNF in cultured mouse cerebellar granule cells
- Effect of electroacupuncture on BDNF expression at ischemia cortex and infarct volume after middle cerebral artery occlusion in rat
- Effects of astragalosides on the expression of BDNF, TrkB and p75NTR mRNA against focal cerebral ischemia-reperfusion injury
- Sustained intracellular Ca2+ elevation induced by a brief BDNF application in rat visual cortex neurons
- The distribution of PGP9. 5, BDNF and NGF in the vallate papilla of adult and developing mice
- Regionally specific induction of BDNF and truncated trkB. T1 receptors in the hippocampal formation after intraseptal injection of kainic acid
- The periodontal Ruffini endings in brain derived neurotrophic factor (BDNF) deficient mice
- TrkB expression and early sensory neuron survival are independent of endogenous BDNF
- The involvement of brain-derived neurotrophic factor (BDNF) in the regeneration of periodontal Ruffini endings following transection of the inferior alveolar nerve
- Selective up‐regulation of P‐ and R‐type Ca2+ channels in rat embryo motoneurons by BDNF
- BDNF activated TrkB/IRR receptor chimera promotes survival of sympathetic neurons through Ras and PI‐3 kinase signaling
- Estrogen affects BDNF expression following chronic constriction nerve injury
- Differential induction of Pax genes by NGF and BDNF in cerebellar primary cultures.
- BDNF gene transcripts in mesencephalic neurons and its differential regulation by NMDA
- NT‐4/5 and LIF, but not NT‐3 and BDNF, promote NPY mRNA expression in cortical neurons in the absence of spontaneous bioelectrical activity
- Inducibility of BDNF gene promoter I detected by calcium-phosphate-mediated DNA transfection is confined to neuronal but not to glial cells
- Chronic supranigral infusion of BDNF in normal and MPTP-treated common marmosets
- Involvement of brain‐derived neurotrophic factor (BDNF) in the development of periodontal Ruffini endings
- BDNF and trkB mRNA expression in neurons of the neonatal mouse barrel field cortex: normal development and plasticity after cauterizing facial vibrissae
- Influence of ethanol on neonatal cerebellum of BDNF gene‐deleted animals: analyses of effects on Purkinje cells, apoptosis‐related proteins, and endogenous …
- Expression of BDNF and TrkB mRNAs in the crista neurosensory epithelium and vestibular ganglia following ototoxic damage
- BDNF/NT4‐5 receptor TrkB and cadherin participate in cell‐cell adhesion
- Sex-specific effects of in utero manipulation of GABAA receptors on pre-and postnatal expression of BDNF in rats
- Localization of putative calcium-responsive regions in the rat BDNF gene
- Differential regulation of BDNF and NT-3 mRNA levels in primary cultures of rat cerebellar neurons
- Effect of NGF, BDNF, bFGF, aFGF and cell density on NPY expression in cultured rat dorsal root ganglion neurones
- Recombinant human brain‐derived neurotrophic factor (rHuBDNF) Disulfide structure and characterization of BDNF expressed in CHO cells
- Conditioned medium from aged monkey fibroblasts stably expressing GDNF and BDNF improves survival of embryonic dopamine neurons in vitro
- Hyperglycemia and hypercapnia suppress BDNF gene expression in vulnerable regions after transient forebrain ischemia in the rat
- Increased expression of endogenous biotin, but not BDNF, in telencephalic song regions during zebra finch vocal learning
- Functional redundancy and gustatory development in BDNF null mutant mice
- Liposome-mediated BDNF cDNA transfer in intact and injured rat brain.
- A 1.7-Mb YAC contig around the human BDNF gene (11p13): integration of the physical, genetic, and cytogenetic maps in relation to WAGR syndrome
- Interactions of neurotrophic factors GDNF and NT-3, but not BDNF, with the immune system following fetal spinal cord transplantation
- BDNF and NT-3 but not CNTF counteract the Ca2+ ionophore-induced apoptosis of cultured cortical neurons: involvement of dual pathways
- BDNF accelerates gene expression in cultured cerebellar granule neurons
- BDNF binding to truncated trkB. T1 does not affect gene expression
- Differential effects of the trophic factors BDNF, NT‐4, GDNF, and IGF‐I on the isthmo‐optic nucleus in chick embryos
- Gene sequences of chicken BDNF and NT-3
- BDNF and TrkB expression in intrastriatal ventral mesencephalic grafts in a rat model of Parkinson’s disease
- Intraventricular application of BDNF and NT-3 failed to protect nucleus basalis magnocellularis cholinergic neurones.
- BDNF and NT‐4 differentiate two pathways in the modulation of neuropeptide protein levels in postnatal hippocampal interneurons
- Differential regulation of p75 and trkB mRNA expression after depolarizing stimuli or BDNF treatment in basal forebrain neuron cultures
- Highest trkB mRNA expression in the entorhinal cortex among hippocampal subregions in the adult rat: contrasting pattern with BDNF mRNA expression
- The effect of ZMS, an active component of Zhimu, on NGF and BDNF in brains of aged rats
- Effect of hypergravity on the mouse basal expression of NGF and BDNF in the retina, visual cortex and geniculate nucleus: correlative aspects with NPY …
- NGF and BDNF in the anterior pituitary lobe of adult rats
- The induction of BDNF and c-fos mRNA in the hippocampal formation after febrile seizures
- Enhancement of NMDA receptor maturation by BDNF in cultured mouse cerebellar granule cells.
- Contribution of BDNF-mediated inhibition in patterning avian skin innervation
- An improved method detects differential NGF and BDNF gene expression in response to depolarization in cultured hippocampal neurons
- Effects of chronic ethanol administration on expression of BDNF and trkB mRNAs in rat hippocampus after experimental brain injury
- The survival response of mesencephalic dopaminergic neurons to the neurotrophins BDNF and NT-4 requires priming with serum: comparison with members of the …
- BDNF and NT‐3 applied in the whisker pad reverse cortical changes after peripheral deafferentation in neonatal rats
- A common mechanism for recombinant human NGF, BDNF, NT‐3, and murine NGF slow unfolding
- Expression of BDNF mRNA in substantia nigra is dependent on target integrity and independent of neuronal activation
- Activation of Ras and protection from apoptotic cell death by BDNF in PC12 cells expressing TrkB
- Dopaminergic regulation of BDNF content in the pituitary intermediate lobe
- Metal-catalyzed oxidation of brain-derived neurotrophic factor (BDNF): Analytical challenges for the identification of modified sites
- Cerebellar pathology in BDNF-/-mice: the classic view of neurotrophins is changing.
- Effects of three Chinese formulas on BDNF, TrkB in rat contex and hippocampus with chronic immobilization stress
- PMA decreases the proliferation of retinal cells in vitro: the involvement of acetylcholine and BDNF
- Synergistic trophic actions on rat basal forebrain neurons revealed by a synthetic NGF/BDNF chimaeric molecule
- Rescue of injury-induced neurofilaments loss by BDNF gene transfection in primary septo-hippocampal cell cultures
- Attenuation of the seizure‐induced expression of BDNF mRNA in adult rat brain by an inhibitor of calcium/calmodulin‐dependent protein kinases
- A stimulus paradigm inducing long-term desensitization of AMPA receptors evokes a specific increase in BDNF mRNA in cerebellar slices.
- Brain-derived neurotrophic factor (BDNF) peptide antibodies: characterization using a Vaccinia virus expression system.
- The effects of intra-vestibular nucleus administration of brain-derived neurotrophic factor (BDNF) on recovery from peripheral vestibular damage in guinea pig
- Plant-derived amino acids increase hippocampal BDNF, NGF, c-fos and hsp70 mRNAs
- Trauma-induced striatal CNTF and BDNF mRNA in hemiparkinsonian rats
- Intraventricular injection of NGF, but not BDNF, induces rapid motor activation that is inhibited by nicotinic receptor antagonists
- Decreased hippocampal BDNF expression after acute systemic injection of quinpirole
- Farnesyltransferase inhibitor FTI-277 prevents autocrine growth stimulation of neuroblastoma by BDNF
- Short-term hypergravity influences NGF and BDNF expression, and mast cell distribution in the lungs and heart of adult male mice.
- Effects of bFGF and BDNF on the cells of injured adult mouse olfactory epithelium in vitro
- Quantitative Analysis of Long-Term Survival and Neuritogenesisin Vitro: Cochleovestibular Ganglion of the Chick Embryo in BDNF, NT-3, NT-4/5, and Insulin
- Silencer-mediated repression and non-mediated activation of BDNF and c-fos gene promoters in primary glial or neuronal cells
- Malonate-induced cortico-motoneuron death is attenuated by NT-4, but not by BDNF or NT-3
- Influence of BDNF and FCS on viability and programmed cell death (PCD) of developing cortical chicken neurons in vitro
- BDNF rapidly induces aspartate release from cultured CNS neurons
- Evidence for a synergistic effect of the HIV-1 envelope protein gp120 and brain-derived neurotrophic factor (BDNF) leading to enhanced expression of somatostatin …
- The cognition-enhancer nefiracetam is protective in BDNF-independent neuronal cell death under the serum-free condition
- BDNF, and NT-4/5 enhance glutamatergic synaptic transmission in cultured hippocampal neurones
- NR2A but not NR2B N-methyl-D-aspartate receptor subunit is altered in the visual cortex of BDNF-knock-out mice
- EFFECTS OF BDNF AND NGF ON THE LONG-TERM CULTURED EMBRYONIC BASAL FOREBRAIN CHOLINERGIC NEURONS IN VITRO [J]
- Expression of NGF, BDNF and NT-3 in satellite cells of dorsal root ganglion
- Genetic transfer of the wobbler gene to a C57BL/6J× NZB hybrid stock: natural history of the motor neuron disease and response to CNTF and BDNF cotreatment
- Rescue of axotomized rubrospinal neurons by brain-derived neurotrophic factor (BDNF) in the developing opossum, Didelphis virginiana
- Metal-catalyzed oxidation of brain-derived neurotrophic factor (BDNF): selectivity and conformational consequences of histidine modification.
- Effect of panax notoginseng saponinsa on the expression of BDNF in rats with cerebral ischemia reperfusion
- Detection and localization of BDNF in vestibular nuclei during the postnatal development of the rat
- Distribution of BDNF and trkB mRNA in the otic region of 3.5 and 4.5 day chick embryos as revealed with a combination of in situ hybridization and tract tracing.
- Molecular cloning and sequencing of the human BDNF gene encoding mature peptide
- BDNF is Expressed at the Crush Site after Spinal Cord Lesion in Newborn Opossum (Monodelphis domestica)
- Expression of tenascin and BDNF during the migration and differentiation of grafted Purkinje and granule cells in the adult rat cerebellum
- Expression of BDNF and trk B mRNAs in comparison to dopamine D1 and D2 receptor mRNAs and tyrosine hydroxylase-immunoreactivity in nigrostriatal in oculo co …
- Expression of BDNF Receptor TrkBmRNA in hypoxia-induced fetal cortical neurons
- Influence of Acupuncture on the Expression of BDNF and TrkB in Chronic Spinal Cord Injury of Rats [J]
- Analysis of BDNF production in the aging gerbil cochlea
- Molecular cloning and heterologous expression of the brain derived neurotrophic factor (BDNF) gene from giant panda
- The effect of acupuncture on the expression of BDNF in the process of spinal plasticity
- Expression of brain‐derived neurotrophic factor (BDNF) mRNA in rat retrosplenial cortex following administration of phencyclidine
- Cerebellopontine Angle Cisternal Infusion of NGF, BDNF and NT-3: Effects on Cochlear Neurons Disconnected from Central Target, Cochlear Nucleus: An in vivo …
- Changes of BDNF mRNA by molecular hybridization during embryonic spinal cord repairing injury of adult rats
- The neurotrophins NT3 and BDNF induce selective specification of neuropeptide coexpression and neuronal connectivity in arcuate and periventricular hypothalamic …
- … ‐activated α2‐macroglobulin inhibits choline acetyltransferase of embryonic basal forebrain neurons and reversal of the inhibition by NGF and BDNF but not NT‐3
- Modulation of proteolytic potential and differentiation by CNTF and BDNF in two mouse neuroblastoma clones: Relation to invasion
- HSV-1 vector mediated transfer of BDNF into cerebellar granule cells.
- The expression of BDNF and NT-3 in dorsal root ganglion following peripheral and central axotomy–an immunohistochemical study
- Effects of BCPT on the expressions of cerebral cortex BDNF and Bax and the ultrastructure of hippocampus of rats treated with chronic unpredictable stress
- Expression of mRNAs for BDNF and NT-3 in Reactive Astrocytes.
- Distribution of NGF, BDNF, NT-3 and NT-4 in the spinal cord of adult cat
- Interaction of NT-4 and BDNF with gp145trkb receptor: effect on cellular metabolism
- Implantation of BDNF-producing packaging cells into brain
- A preliminary exploration of autocrine and paracrine for BDNF and NT-3 in adult cat neurons of dorsal root ganglion-In situ hybridization and immunohistochemical …
- The gene encoding bovine brain-derived neurotrophic factor (BDNF)
- Stress and BDNF signal transduction: implications for stress-related psychiatric disorders
- Relation between BDNF and synaptic reorganization of hippocampal mossy fibers
- EXPRESSION OF NEUROTROPHIC FACTORS (NGF, BDNF, NT-3 AND CNTF) AND RECEPTORS trkA, trkB AND trkC IMMUNOREACTIVITY BY LUMBAR SPINAL …
- Effects of BDNF and NT-3on growth and development of neurons from spinal cord of embryonic rat in vitro [J]
- Effects of Brain derived neurotrophic factor (BDNF) on substantial nigra dopaminergic neurons in Parkinson dis-ease rats [J]
- Expression of BDNF and FGF-2 following axotomy in rat facial motoneurons
- THE EFFECTS OF BDNF AND NGF ON THE GROWTH AND DEVELOPMENTOF EMBRYONIC CHOLINERGIC NEURONS IN VITRO [J]
- Suppression of BDNF‐induced expression of neuropeptide Y (NPY) in cortical cultures by oxygen‐glucose deprivation: A model system to study ischemic mechanisms …
- Facilitation of synaptic plasticity and improvement of learning disorder by brain-derived neurotrophic factor (BDNF)
- Minor immunoreactivity in GDNF-, BDNF-, or NT-3-treated substantia Nigra allografts
- THE EXPRESSION CHANGES OF NGF, BDNF AND NT-3 IN SATELLITE CELLS FOLLOWING PARTIAL DORSAL ROOT RHIZOTOMY [J]
- The expression of neurotrophic factors (NGF, BDNF) and receptors, TrkA, TrkB and TrkC in the spinal cord of the monkey
- THE IMMUNOHISTOCHEMICAL EVIDENCE FOR THE DISTRIBUTION OF NGF, BDNF, NT-3, GDNF IN SUBPOPULATION OF NEURONS OF DORSAL ROOT …
- The Expression on the BDNF, NT_3 and their mRNA in Dorsal Root Ganglion of Adult Cat
- The Expression and distribution of NGF and BDNF in adult rat motocortex following spinal cord complete transection
- Construction of recombinant adenovirus expressing BDNF and its expression in expanded rat mesenchymal stem cells in vitro
- Biological properties of brain-derived neurotrophic factor (BDNF)
- Selection of the most effective small interfering RNA inhibiting the expression of BDNF in microglial cells and detection of its inhibitory effect
- Effects of BDNF and NT-3 on AChE-or NADPH-d-positive neurons in embryonic rat spinal cord cultures
- Expression of Brain-derived Neurotrophic Factor (BDNF) Gene in Rat Myoblast Cells.
- Structure and regulation of BDNF and NT-4 genes
- Expression of Brain-derived Neurotrophic Factor (BDNF) in Injured Rat Brain [J]
- Modulation of BDNF and NGF on the development of embryonic cholinergic neurons in brain grafts of AD model rats
- Differential distribution of BDNF and TRKB in regenerating dorsal column axons
- A continuous supply of BDNF is necessary for sustained auditory neuron survival in deafened guinea pigs
- Autonomic and sensory innervation of skin and hair follicles in BDNF-overexpressing and BDNF-knockout mice
- BDNF is involved in expression of long-term potentiation in visual cortex of young rats.
- BDNF promotes robust survival of retinal ganglion cells but not axon regeneration within the adult rat optic nerve
- Effects on neurtie outgrowth in conditioned media derivered from BDNF gene-transferred fibroblast in vitro
- EFFECTS OF BDNF AND NGF ON THE DEVELOPMENT AND GROWTH OF NITRIC OXIDE SYNTHASE POSITIVE NEURONS IN BRAIN GRAFTS OF AD MODEL …
- Retrograde HRP tracing after transplantation of BDNF genetically modified NSCs at spinal cord injury in rat
- Changes of BDNF and TrkB expression in rat motocortex following complete spinal cord transection
- Regulation of BDNF and Its Receptor TrkB in retina of normal aged mice and senescence-accelerated mice
- EXPERIMENTAL STUDY ON THE EFFECTS OF EXPRESSION OF AChE, ChAT, BDNF, trkB, BDNF mRNA, trkB mRNA IN THE MBN OF RAT FOREBRAIN AFTER …
- Molecular cloning and sequence of the coding region of brain derived neurotrophic factor (BDNF) gene from Helarctos malayanus
- The neurotrophic effect of endogeneous NT-3 and BDNF of fetal mouse on the neurons of spinal cord
- Molecular cloning and sequencing of the brain derived neurotrophic factor (BDNF) gene from lesser panda
- Protective effect of adenovirus-mediated BDNF gene expression on spinal axon following in rats after spinal cord injury [J]
- Effects of BCEF0083on Hippocampus Neurons and mRNA Expression of BDNF in Chronic Stress Depression Rat Models BCEF0083
- A brain-derived neurotrophic factor (BDNF) related system is involved in the maintenance of the polyinnervate Torpedo electric organ
- BDNF decrease in response to stress is not seen in rats bred for learned helplessness
- Potential Therapeutic Use of BDNF or NT-4/5 in Parkinson’s and Alzheimer’s Diseases
- Changes of BDNF level expression in Hippocampal and Habenular nucles in experimental depression rats
- Effect of chronic fluxetine administration on expression of brain-derived neurotrophic factors (BDNF) mRNA in hippocampal region of rat brain
- A comparison of the kinetic characters of NT-3, NT-4 and BDNF retrogradely transported in facial nerve
- Eukaryotic Expression in COS7 Cells and Biological Activity of Human Brain-derived Neurotrophic Factor (BDNF).
- Neurotrophins and murine hair follicle morphogenesis: expression patterns of NT-3, NT-4, BDNF, TrkB and TrkC and indications for a functional role in hair follicle …
- LONG TERM RESTORATION OF GDNF AND BDNF ON LESIONED MOTONEURONS
- The Change of BDNF Expression and Its mRNA in Neurons and Satellite Cells of Spared Root Ganglion Following Partial Dorsal Root Rhizotomy
- Effect of gonadotropins upon BDNF production in human follicular cumulus cells
- Neuronal tracing and immunohistochemistry of BDNF gene transfected olfactory ensheathing cells transplant in spinal cord injury
- The protection effect of BDNF mediated by adenovirus to the serum free cultured SH-SY5Y cells
- Experimental study on the effects of recombinate human BDNF in the cultured neurons of Alzheimer^ s disease model
- Transplantation of Schwann cell line clones secreting GDNF or BDNF into the retina of the Royal College of Surgeons rat prolongs visual function
- Regulation of the expression of BDNF and its receptors in the developing nervous system
- BDNF is produced in NGF-responsive sensory neurons of rats
- Expression of Genes Coding NGF and BDNF Human Proteins in Embryos of Transgenic Stocks of Drosophila melanogaster
- Analysis of BDNF mRNA expression induced by calcium influx into neurons
- BDNF-immunoreactive structures in the primate central nervous system
- BDNF mRNA Expression and Calcium Influx Pathways in Kainate-induced Neurotoxicity
- BDNF (brain-derived neurotrophic factor) induces glutamate and aspartate release from cultured rat CNS neurons
- BDNF Expression in the OECs Infected by Ad-BDNF in Vitro and Surviving the Primary Cultured Spinal Neurons
- Effects of Intracerebral Transplantation of Genetically Modified Myoblasts Producing BDNF on Different Brain Regions of Neonatal Rats Subjected to Hypoxic-ischemic …
- Construction of recombinant adenovirus expressing BDNF and its expression in expanded rat mesenchymal stem cells in vitro
- Construction and identification of recombinant BDNF and pLCNX plasmid
- Effects of Enriched Enviroment on Expression of BDNF and Motor Performence after Alcohol-induced Brain Injury in Neonatal Rats
- Effects of cannabinoid on the expression of PKAC-?, c-fos and BDNF in cerebral cortex after ICH
- Transfection of the BDNF gene increases survival and serotonin synthesis in transplanted serotonergic neurons.
- The subcellular localization and function of endogenous BDNF in the adult rat CNS.
- Dopamine content in the striatum of rat Parkinson model by BDNF gene therapy
- Neuroprotective effect of BDNF in a murine model of Parkinson’s disease.
- Effects of BDNF on the exocytotic release of neurotransmitters.
- The effect of a global birth asphyxia on the ontogeny of BDNF and NGF protein expression in the brain
- Postsynaptic Action of BDNF in Synaptic Plasticity
- Correlation between the expression of neuron-specific protein and apoptosis in the process of differentiation from rat bone marrow stromal cells into neuron with BDNF
- Brain-Derived Neurotrophic Factor (BDNF) Regulates Glucose Metabolism in Obese Diabetic Mice
- CaRF Increases BDNF Expression
- Mechanism of hippocampal neuron death in the trisomy 16 mouse: Failure of BDNF signaling
- Astrocytes retrovirally transduced with BDNF elicit behavioral improvement in a rat model of Parkinson’s disease
- A study of BDNF and TrKB in rat brain after fluid percussion injury by the immunohistochemistry
- The functions of BDNF/TrkB signaling during chick retinal development.
- Neurotrophins in neuroendocrine control: brain derived-neurotrophic factor (BDNF) and somatostatin involvement in the stress response and reproductive …
- Intracellular signal transduction following stimulation with BDNF in culturei
- The gene expressions at the spinal cord injury site of rat after transplantation of BDNF genetically modified NSCs
- Synergic effects of neurotrophins NGF and BDNF on the development of the fetal forebrain cholinergic neurons in vitro and in vivo
- Response: BDNF and epilepsy–the bad could turn out to be good
- The Mechanism of BDNF Evoked Release of Dopamine from the Rabbit Retina
- Activity-dependent regulation of BDNF expression (Brain-derived neurotrophic factor).
- Changes in Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF) and Receptor Tyrosine Kinases (Trk) in Micturition Reflexes after …
- Effects of adenosine A_1 receptor antagonist on the hippocampal BDNF protein expression and endoplasmic reticulum content of rats
- Study on the expression of BDNF after status convulsion in wistar rats and seizure-like discharge of cultured hippocampal neurons
- Human Trabecular Meshwork Cells from Normal and Glaucomatous Donors Respond to TGFb2 and BDNF Treatment Differently
- Effects of Bushen Xingnao jiedu Fang on expressions of NGF and BDNF after herpes simplex virus infection in rat brain
- Expression of brain-derived neurotrophic factor in myoblasts transfected by PSVCEP BDNF-CAT with lipofect AMINE
- BDNF administration after traumatic brain injury in the rat
- BDNF requirements within the neostriatum and substantia nigra of mice: A study of conditional BDNF expression.
- The Expression of BDNF mRNA in the Hippocampal Formation after Febrile Seizure
- The role of endogenous NT-3 and BDNF in cocaine-induced behavioral sensitization: An immunohistochemical and behavioral analysis.
- Effects of NGF and BDNF on superoxide anion-triggered apoptosis of PC12 cells
- Age-related changes in levels of NGF, BDNF and NT-3 in the mouse brain
- Effects of BDNF on ocular dominance column plasticity in kitten visual cortex.
- A protective effect of BDNF against glutamate neurotoxicity in cultured retinal neurons
- Brain-derived Neurotrophic Factor (BDNF) Enhances Depolarization-induced Glutamate Release through Activation of Phospholipase C-γ and Mitogen …
- Carl Cotman and The Effects of Voluntary Exercise on Increased BDNF Expression
- The comparison on the distribution of NGF and BDNF in cerebral cortex of adult rat–Immunohistochemical study
- Molecular basis of the receptor specificity of NGF and BDNF and the cloning of a novel member of the neurotrophin family
- Effects of BDNF and NT-3 on growth and development of fetal rats^ spinal cord neurons
- Map Kinase and PI3 Kinase Pathways Regulate BDNF-Medicated Muller Cell Survival
- Transfer BDNF Plasmid by Electroporation Supports the Survival of Axotomized RGCs in Adult Rat
- A novel BDNF gene promoter directs expression to skeletal muscle
- BDNF Regulation of NMDA Receptor Function in the Rat Retina