CALORIE RESTRICTION & LIFESPAN EXTENSION | Interstellar Blends

LIPID DROPLETS

September 12, 2021

PHLORIZIN

September 21, 2021

Calorie restriction—the SIR2 connection
How does Calorie restriction work?
Calorie restriction and aging: review of the literature and implications for studies in humans
Aging, adiposity, and Calorie restriction
Calorie restriction and SIR2 genes—towards a mechanism
Requirement of NAD and SIR2 for life-span extension by Calorie restriction in Saccharomyces cerevisiae
Sir2-independent life span extension by Calorie restriction in yeast
Sir2 mediates longevity in the fly through a pathway related to Calorie restriction
Calorie restriction and aging: A life‐history analysis
Increase in activity during Calorie restriction requires Sirt1
Relative effects of Calorie restriction and weight loss in noninsulin-dependent diabetes mellitus
Calorie restriction in rhesus monkeys
The inflammation hypothesis of aging: molecular modulation by Calorie restriction
Calorie restriction and cancer prevention: metabolic and molecular mechanisms
Calorie restriction mimetics: an emerging research field
Development of Calorie restriction mimetics as a prolongevity strategy
Molecular mechanisms linking Calorie restriction and longevity
Long-term Calorie restriction is highly effective in reducing the risk for atherosclerosis in humans
Tissue-specific regulation of SIRT1 by Calorie restriction
Calorie restriction and prevention of age-associated chronic disease
Calorie restriction, SIRT1 and metabolism: understanding longevity
Calorie restriction in primates: will it work and how will we know?
Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans
HST2 mediates SIR2-independent life-span extension by Calorie restriction
SIR2: a potential target for Calorie restriction mimetics
Mammalian sirtuins—emerging roles in physiology, aging, and Calorie restriction
Nicotinamide and PNC1 govern lifespan extension by Calorie restriction in Saccharomyces cerevisiae
Calorie restriction and the exercise of chromatin
Molecular inflammation hypothesis of aging based on the anti‐aging mechanism of Calorie restriction
Calorie restriction: what recent results suggest for the future of ageing research
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
Effect of Calorie restriction with or without exercise on body composition and fat distribution
Oxidative stress and mitochondrial function with aging–the effects of Calorie restriction
Calorie restriction alters mitochondrial protein acetylation
Sir2 and Calorie restriction in yeast: a skeptical perspective
Calorie restriction and stroke
Intermittent versus daily Calorie restriction: which diet regimen is more effective for weight loss?
SIRT1 transgenic mice show phenotypes resembling Calorie restriction
Calorie restriction increases muscle mitochondrial biogenesis in healthy humans
Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial
Short-term Calorie restriction enhances skeletal muscle stem cell function
Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency
Effect of Calorie restriction on the metabolic history of chronologically aging yeast
Calorie restriction: is AMPK a key sensor and effector?
Tor1/Sch9-regulated carbon source substitution is as effective as Calorie restriction in life span extension
NRF2, cancer and Calorie restriction
Calorie restriction increases life span: a molecular mechanism
Chronic Calorie restriction attenuates experimental autoimmune encephalomyelitis
Calorie restriction and resveratrol in cardiovascular health and disease
Calorie restriction extends yeast life span by lowering the level of NADH
Calorie restriction and aging in nonhuman primates
Mitochondria—a nexus for aging, Calorie restriction, and sirtuins?
Calorie restriction: decelerating mTOR-driven aging from cells to organisms (including humans)
The neuroprotective properties of Calorie restriction, the ketogenic diet, and ketone bodies
The coordination of nuclear and mitochondrial communication during aging and Calorie restriction
Yeast life-span extension by Calorie restriction is independent of NAD fluctuation
Calorie restriction and cardiometabolic health
Modulation of PPAR in aging, inflammation, and Calorie restriction
Approaches for quantifying energy intake and% Calorie restriction during Calorie restriction interventions in humans: the multicenter CALERIE study
Calorie restriction reduces oxidative stress by SIRT3-mediated SOD2 activation
Regulation of energy metabolism by inflammation: a feedback response in obesity and Calorie restriction
Effect of Calorie restriction on resting metabolic rate and spontaneous physical activity
Increased life span due to Calorie restriction in respiratory-deficient yeast
Suppression of adenocarcinoma by the immunological consequences of Calorie restriction
Calorie restriction and susceptibility to intact pathogens
Sarcopenia of aging: underlying cellular mechanisms and protection by Calorie restriction
Autophagy in the heart and liver during normal aging and Calorie restriction
Inadequate nutrition and chronic Calorie restriction in adolescent ballerinas
Calorie restriction in nonhuman primates: effects on diabetes and cardiovascular disease risk.
Effect of long-term Calorie restriction with adequate protein and micronutrients on thyroid hormones
Activity measures in rhesus monkeys on long-term Calorie restriction
Examination of cognitive function during six months of Calorie restriction: results of a randomized controlled trial
Life span extension by Calorie restriction depends on Rim15 and transcription factors downstream of Ras/PKA, Tor, and Sch9
Does Calorie restriction induce mitochondrial biogenesis? A reevaluation
Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase
Calorie restriction on drinking days: An examination of drinking consequences among college students
Calorie restriction in biosphere 2: alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period
Targeted disruption of growth hormone receptor interferes with the beneficial actions of Calorie restriction
Resveratrol as a Calorie restriction mimetic: therapeutic implications
A randomized trial of counseling for fat restriction versus Calorie restriction in the treatment of obesity.
Oral glycotoxins determine the effects of Calorie restriction on oxidant stress, age-related diseases, and lifespan
Calorie restriction inhibits the age-related dysregulation of the cytokines TNF-α and IL-6 in C3B10RF1 mice
Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
Orexin signaling mediates the antidepressant-like effect of Calorie restriction
Nonhuman primate Calorie restriction
Effects on weight reduction of strong monetary contracts for Calorie restriction or weight loss
Endocrine alterations in response to Calorie restriction in humans
Life extension by Calorie restriction in humans
Calorie restriction and bone health in young, overweight individuals
Dietary interventions to extend life span and health span based on Calorie restriction
SIRT4 inhibits glutamate dehydrogenase and opposes the effects of Calorie restriction in pancreatic β cells
Modulation of redox-sensitive transcription factors by Calorie restriction during aging
Antiaging, longevity and Calorie restriction
Intermittent fasting combined with Calorie restriction is effective for weight loss and cardio-protection in obese women
Skeletal muscle autophagy and apoptosis during aging: effects of Calorie restriction and life-long exercise
Effects of a behavioral weight loss program stressing Calorie restriction versus Calorie plus fat restriction in obese individuals with NIDDM or a family history of diabetes
Diet and Calorie restriction
Neuronal SIRT1 regulates endocrine and behavioral responses to Calorie restriction
Calorie restriction and the nutrient sensing signaling pathways
lifespan extension by Calorie restriction relies on the Sty1 MAP kinase stress pathway
Calorie restriction lowers body temperature in rhesus monkeys, consistent with a postulated anti-aging mechanism in rodents
Effect of exercise and Calorie restriction on biomarkers of aging in mice
MSN2 and MSN4 Link Calorie restriction and TOR to Sirtuin-Mediated lifespan extension in Saccharomyces cerevisiae
Effects of Calorie restriction on cardioprotection and cardiovascular health
Calorie restriction, aging and longevity
Glycolytic inhibition as a strategy for developing Calorie restriction mimetics
Bioenergetics of aging and Calorie restriction
Calorie restriction and age‐related oxidative stress
Response to comment on” HST2 mediates SIR2-independent life-span extension by Calorie restriction“
Calorie restriction increases fatty acid synthesis and whole body fat oxidation rates
Alternate day Calorie restriction improves clinical findings and reduces markers of oxidative stress and inflammation in overweight adults with moderate asthma
Muscle fiber‐specific apoptosis and TNF‐α signaling in sarcopenia are attenuated by life‐long Calorie restriction
Sexual differentiation, pregnancy, Calorie restriction, and aging affect the adipocyte-specific secretory protein adiponectin
Effect of short term Calorie restriction on pro-inflammatory NF-kB and AP-1 in aged rat kidney
Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by Calorie restriction
Oxidative damage to specific proteins in replicative and chronological-aged Saccharomyces cerevisiae: common targets and prevention by Calorie restriction
Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice
Effects of long-term Calorie restriction and endurance exercise on glucose tolerance, insulin action, and adipokine production
Calorie restriction and cellular proliferation in various tissues of the female Swiss Webster mouse
Effect of Calorie restriction with or without exercise on insulin sensitivity, β-cell function, fat cell size, and ectopic lipid in overweight subjects
Effect of Calorie restriction on subjective ratings of appetite
Dynamic regulation of PGC‐1α localization and turnover implicates mitochondrial adaptation in Calorie restriction and the stress response
Alteration of soluble adhesion molecules during aging and their modulation by Calorie restriction
Molecular mechanisms of life-and health-span extension: role of Calorie restriction and exercise intervention
Calorie restriction attenuates inflammatory responses to myocardial ischemia-reperfusion injury
Small molecule activators of SIRT1 replicate signaling pathways triggered by Calorie restriction in vivo
Long‐term effects of Calorie restriction on serum sex‐hormone concentrations in men
Interactions between light, mealtime and Calorie restriction to control daily timing in mammals
Efficacy of fasting Calorie restriction on quality of life among aging men
Modulation of age-induced apoptotic signaling and cellular remodeling by exercise and Calorie restriction in skeletal muscle
FoxO1 is involved in the antineoplastic effect of Calorie restriction
Seizure resistance is dependent upon age and Calorie restriction in rats fed a ketogenic diet
Neuroendocrine factors in the regulation of inflammation: excessive adiposity and Calorie restriction
Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney
Effect of Calorie restriction on in vivo glucose metabolism by individual tissues in rats
Role of sirtuins, Calorie restriction and physical activity in aging
Adult-onset Calorie restriction and fasting delay spontaneous tumorigenesis in p53-deficient mice
The effect of long term Calorie restriction on in vivo hepatic proteostatis: a novel combination of dynamic and quantitative proteomics
Suppression of apoptosis by Calorie restriction in aged kidney
Long-term Calorie restriction, but not endurance exercise, lowers core body temperature in humans
Effect of exercise intensity on abdominal fat loss during Calorie restriction in overweight and obese postmenopausal women: a randomized, controlled trial
Calorie restriction up-regulates the plasma membrane redox system in brain cells and suppresses oxidative stress during aging
Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins
Biological approaches to mechanistically understand the healthy life span extension achieved by Calorie restriction and modulation of hormones
Physiologic changes in humans subjected to severe, selective Calorie restriction for two years in biosphere 2: health, aging, and toxicological perspectives.
Modulation of glutathione and thioredoxin systems by Calorie restriction during the aging process
Short‐term Calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress
Deterioration of spatial and nonspatial reference and working memory in aged rats: protective effect of life-long Calorie restriction
Effects of Calorie restriction on life span of microorganisms
High Osmolarity Extends Life Span in Saccharomyces cerevisiae by a Mechanism Related to Calorie restriction
Effect of 6-month Calorie restriction on biomarkers of longevity, metabolic adaptation, and oxidative stress in overweight individuals: a randomized controlled trial
Calorie restriction accelerates the catabolism of lean body mass during 2 wk of bed rest
Effects of adult-onset Calorie restriction on anxiety-like behavior in rats
Calorie restriction and diet composition modulate spontaneous intestinal tumorigenesis in ApcMin mice through different mechanisms
The controversial links among Calorie restriction, SIRT1, and resveratrol
Honoring Clive McCay and 75 years of Calorie restriction research
Calorie restriction for treatment of gestational diabetes
Calorie restriction prevents hypertension and cardiac hypertrophy in the spontaneously hypertensive rat
Disruption of growth hormone receptor prevents Calorie restriction from improving insulin action and longevity
Effect of Calorie restriction on the free-living physical activity levels of nonobese humans: results of three randomized trials
Housing density does not influence the longevity effect of Calorie restriction
Calories and carcinogenesis: lessons learned from 30 years of Calorie restriction research
Inpatient treatment of obese children: a multicomponent programme without stringent Calorie restriction
Effects of short-and medium-term Calorie restriction on muscle mitochondrial proton leak and reactive oxygen species production
Long-lived Indy and Calorie restriction interact to extend life span
Defect in insulin binding to receptors in obese man. Amelioration with Calorie restriction.
Macrophages and adipocytes in human obesity: adipose tissue gene expression and insulin sensitivity during Calorie restriction and weight stabilization
Calorie restriction reduces the incidence of myeloid leukemia induced by a single whole-body radiation in C3H/He mice
Dehydroepiandrosterone sulfate: a biomarker of primate aging slowed by Calorie restriction
Calorie restriction attenuates age-related alterations in the plasma membrane antioxidant system in rat liver
Influence of Calorie restriction on measures of age-related cognitive decline: role of increased physical activity
The role of protein and Calorie restriction in outcome from Salmonella infection in mice
Distinct effects of Calorie restriction and resveratrol on diet-induced obesity and fatty liver formation
Cellular mechanisms of cardioprotection by Calorie restriction: state of the science and future perspectives
Early‐onset Calorie restriction conserves fiber number in aging rat skeletal muscle
Calorie restriction and glucose regulation
Sirtuin regulation in Calorie restriction
Calorie Source, Calorie restriction, Immunity and Aging of (NZB/NZW)F1 Mice
Calorie restriction reduces pinealectomy‐induced insulin resistance by improving GLUT4 gene expression and its translocation to the plasma membrane
Calorie restriction enhances T-Cell–mediated immune response in adult overweight men and women
Akt2 is essential for the full effect of Calorie restriction on insulin-stimulated glucose uptake in skeletal muscle
Calorie restriction as an anti-invasive therapy for malignant brain cancer in the VM mouse
Immune response after experimental allergic encephalomyelitis in rats subjected to Calorie restriction
Sirtuin‐independent effects of nicotinamide on lifespan extension from Calorie restriction in yeast
Short-term Calorie restriction in male mice feminizes gene expression and alters key regulators of conserved aging regulatory pathways
Calorie restriction is more effective for obesity treatment than dietary fat restriction,
Calorie restriction in nonhuman primates: mechanisms of reduced morbidity and mortality.
Membrane alteration as a basis of aging and the protective effects of Calorie restriction
Plasma glucose and the action of Calorie restriction on aging
… hypertrophy,“adaptation,” and “decompensation” associated with glomerular enlargement and glomerulosclerosis in the aging rat: prevention by Calorie restriction
Calorie restriction in obesity: prevention of kidney disease in rodents
Calorie restriction improves cardiovascular risk factors via reduction of mitochondrial reactive oxygen species in type II diabetic rats
Long-term Calorie restriction reduces energy expenditure in aging monkeys
Calorie restriction increases cerebral mitochondrial respiratory capacity in a NO•-mediated mechanism: impact on neuronal survival
Beyond the rodent model: Calorie restriction in rhesus monkeys
Biological significance of protein modifications in aging and Calorie restriction
NAD+ metabolite levels as a function of vitamins and Calorie restriction: evidence for different mechanisms of longevity
Influence of aging and Calorie restriction on MAPKs activity in rat kidney
The effect on health of alternate day Calorie restriction: eating less and more than needed on alternate days prolongs life
Why Calorie restriction would work for human longevity
Effect of Calorie restriction and refeeding on skin wound healing in the rat
The activation of NF-κB through Akt-induced FOXO1 phosphorylation during aging and its modulation by Calorie restriction
Calorie restriction increases cigarette use in adult smokers
Long-term Calorie restriction reduces proton leak and hydrogen peroxide production in liver mitochondria
Calorie restriction and aging: the ultimate “cleansing diet”
Calorie restriction falters in the long run
Improvement in coronary heart disease risk factors during an intermittent fasting/Calorie restriction regimen: Relationship to adipokine modulations
Calorie restriction modulates inactivity-induced changes in the inflammatory markers C-reactive protein and pentraxin-3
Lifelong Calorie restriction alleviates age-related oxidative damage in peripheral nerves
Validation study of energy expenditure and intake during Calorie restriction using doubly labeled water and changes in body composition
Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo
Calorie restriction attenuates Alzheimer’s disease type brain amyloidosis in Squirrel monkeys (Saimiri sciureus)
Calorie restriction, ad Libitum Feeding, and Cancer
Synergistic induction of lipid catabolism and anti-inflammatory lipids in white fat of dietary obese mice in response to Calorie restriction and n-3 fatty acids
Food reward in the obese and after weight loss induced by Calorie restriction and bariatric surgery
Age-related cardiovascular disease and the beneficial effects of Calorie restriction
Anti-inflammatory action of dietary fish oil and Calorie restriction
Aging and lifelong Calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3 …
Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during Calorie restriction
Long-term potentiation is lost in aged rats but preserved by Calorie restriction.
Hungry for life: How the arcuate nucleus and neuropeptide Y may play a critical role in mediating the benefits of Calorie restriction
Effects of Calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture in young C57BL/6 mice
Calorie restriction delays lipid oxidative damage in Drosophila melanogaster
Suppression of cellular and humoral immunity to T-dependent antigens by Calorie restriction
Mild Calorie restriction induces fat accumulation in female C57BL/6J mice
Moderate Calorie restriction improves cardiac remodeling and diastolic dysfunction in the Dahl-SS rat
Targeting energy metabolism in brain cancer through Calorie restriction and the ketogenic diet
Role of sirtuins and Calorie restriction in neuroprotection: implications in Alzheimer’s and Parkinson’s diseases
Long-term effect of mediterranean-style diet and Calorie restriction on biomarkers of longevity and oxidative stress in overweight men
The malate–aspartate NADH shuttle components are novel metabolic longevity regulators required for Calorie restriction-mediated life span extension in yeast
Calorie restriction increases cell surface GLUT-4 in insulin-stimulated skeletal muscle
Calorie restriction in mice: effects on body composition, daily activity, metabolic rate, mitochondrial reactive oxygen species production, and membrane fatty acid …
The role of Calorie restriction and SIRT1 in prion-mediated neurodegeneration
Improved insulin sensitivity by Calorie restriction is associated with reduction of ERK and p70S6K activities in the liver of obese Zucker rats
Influence of diet and Calorie restriction on the initiation and promotion of skin carcinogenesis in the SENCAR mouse model
Effects of aging and Calorie restriction on the global gene expression profiles of mouse testis and ovary
Calorie restriction with a high-fat diet effectively attenuated inflammatory response and oxidative stress-related markers in obese tissues of the high diet fed …
Effects of increased physical activity and mild Calorie restriction on heart rate variability in obese women
Calorie restriction: A new therapeutic intervention for age-related dry eye disease in rats
Calorie restriction in nonhuman primates: assessing effects on brain and behavioral aging
Regulation of yeast sirtuins by NAD+ metabolism and Calorie restriction
Effect of 6‐month Calorie restriction and exercise on serum and liver lipids and markers of liver function
Visceral fat: higher responsiveness of fat mass and gene expression to Calorie restriction than subcutaneous fat
Effects of dietary Calorie restriction or exercise on the PI3K and ras signaling pathways in the skin of mice
The response to Calorie restriction in mammals shows features also common to hibernation: a cross-adaptation hypothesis
Calorie restriction enhances the expression of key metabolic enzymes associated with protein renewal during aging
Adipogenic signaling in rat white adipose tissue: modulation by aging and Calorie restriction
Twenty‐four‐hour ghrelin is elevated after Calorie restriction and exercise training in non‐obese women
Exercise with Calorie restriction improves insulin sensitivity and glycogen synthase activity in obese postmenopausal women with impaired glucose tolerance
The effect of age and Calorie restriction on HIF-1-responsive genes in aged liver
SIRT3 in Calorie restriction: can you hear me now?
Linking Calorie restriction to longevity through sirtuins and autophagy: any role for TOR
Bioenergetics and permeability transition pore opening in heart subsarcolemmal and interfibrillar mitochondria: effects of aging and lifelong Calorie restriction
Calorie restriction on insulin resistance and expression of SIRT1 and SIRT4 in rats
Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus Calorie restriction
Dose‐dependent effects of Calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin‐like growth factor‐1
Increase in daily LH secretion in response to short-term Calorie restriction in obese women with PCOS
Assimilation of endogenous nicotinamide riboside is essential for Calorie restriction-mediated life span extension in Saccharomyces cerevisiae
Calorie restriction reduces rDNA recombination independently of rDNA silencing
Loss of AMP-activated protein kinase-α2 impairs the insulin-sensitizing effect of Calorie restriction in skeletal muscle
Daily meal timing is not necessary for resetting the main circadian clock by Calorie restriction
Glutathione is necessary to ensure benefits of Calorie restriction during ageing in Saccharomyces cerevisiae
Weight gain with risperidone among patients with mental retardation: effect of Calorie restriction
Effect of chronic and intermittent Calorie restriction on serum adiponectin and leptin and mammary tumorigenesis
Pre‐and postnatal Calorie restriction perturbs early hypothalamic neuropeptide and energy balance
Effect of different levels of Calorie restriction on azoxymethane-induced colon carcinogenesis in male F344 rats
Vascular aging: molecular modulation of the prostanoid cascade by Calorie restriction
Calorie restriction ameliorates neurodegenerative phenotypes in forebrain-specific presenilin-1 and presenilin-2 double knockout mice
Yeast as a model to understand the interaction between genotype and the response to Calorie restriction
Transcriptional response according to strength of Calorie restriction in Saccharomyces cerevisiae.
Mild mitochondrial uncoupling and Calorie restriction increase fasting eNOS, akt and mitochondrial biogenesis
Molecular exploration of age-related NF-κB/IKK downregulation by Calorie restriction in rat kidney
PPARG genotype accounts for part of individual variation in body weight reduction in response to Calorie restriction
Preferential reductions in intermuscular and visceral adipose tissue with exercise-induced weight loss compared with Calorie restriction
Calorie restriction, oxidative stress and longevity
Calorie restriction at increasing levels leads to augmented concentrations of corticosterone and decreasing concentrations of testosterone in rats
Calorie restriction effects on silencing and recombination at the yeast rDNA
Calorie restriction modulates renal expression of sterol regulatory element binding proteins, lipid accumulation, and age-related renal disease
Short-term Calorie restriction improves disease-related markers in older male rhesus monkeys (Macaca mulatta)
The GOAT-ghrelin system is not essential for hypoglycemia prevention during prolonged Calorie restriction
Extreme Calorie restriction and energy source starvation in Saccharomyces cerevisiae represent distinct physiological states
Effects of Calorie restriction on transforming growth factor β1 and proinflammatory cytokines in murine Sjogren’s syndrome
Calorie restriction limits the generation but not the progression of mitochondrial abnormalities in aging skeletal muscle
Calorie restriction protects against age‐related rat aorta sclerosis
Experimental allergic encephalomyelitis in male Lewis rats subjected to Calorie restriction
Intermittent Calorie restriction delays prostate tumor detection and increases survival time in TRAMP mice
Molecular architecture of myelinated peripheral nerves is supported by Calorie restriction with aging
Rapamycin partially mimics the anticancer effects of Calorie restriction in a murine model of pancreatic cancer
Differential effects of Calorie restriction and exercise on the adipose transcriptome in diet-induced obese mice
One day of moderate energy deficit reduces fasting and postprandial triacylglycerolemia in women: the role of Calorie restriction and exercise
Chronic Calorie restriction increases susceptibility of laboratory mice (Mus musculus) to a primary intestinal parasite infection
Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity
Calorie restriction‐induced maternal longevity is transmitted to their daughters in a rotifer
2-Deoxy-D-glucose feeding in rats mimics physiologic effects of Calorie restriction
Effect of Calorie restriction on the production and responsiveness to interleukin 2 in (NZB× NZW) F1 mice
Calorie restriction increases insulin-stimulated glucose transport in skeletal muscle from IRS-1 knockout mice.
Effects of dietary protein and Calorie restriction in clinically normal cats and in cats with surgically induced chronic renal failure.
Resveratrol treatment in mice does not elicit the bradycardia and hypothermia associated with Calorie restriction
Life‐long Calorie restriction (CR) increases expression of apoptosis repressor with a caspase recruitment domain (ARC) in the brain
SIRT1, a Calorie restriction mimetic, in a new therapeutic approach for type 2 diabetes mellitus and diabetic vascular complications
Regulation of selenoproteins and methionine sulfoxide reductases A and B1 by age, Calorie restriction, and dietary selenium in mice
Effects of aging and Calorie restriction on white matter in rhesus macaques
Calorie restriction modifies ubiquinone and COQ transcript levels in mouse tissues
… bone mineral density is not associated with significantly reduced bone quality in men and women practicing long‐term Calorie restriction with adequate nutrition
Maternal gestational protein-Calorie restriction decreases the number of glomeruli and causes glomerular hypertrophy in adult hypertensive rats
Excessive adiposity, Calorie restriction, and aging
A role for neuronal cAMP responsive-element binding (CREB)-1 in brain responses to Calorie restriction
Brief Calorie restriction increases Akt2 phosphorylation in insulin-stimulated rat skeletal muscle
Energy availability and mammary carcinogenesis: effects of Calorie restriction and exercise.
Life long Calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats
Cellular adaptation contributes to Calorie restriction-induced preservation of skeletal muscle in aged rhesus monkeys
Calorie restriction reduces the influence of glucoregulatory dysfunction on regional brain volume in aged rhesus monkeys
Dietary adherence to long‐term controlled feeding in a Calorie‐restriction study in overweight men and women
The effects of physiological adaptations to Calorie restriction on global cell proliferation rates
Regulation of forkhead transcription factor FoxO3a contributes to Calorie restriction-induced prevention of Alzheimer’s disease-type amyloid neuropathology …
Effects of weight loss and Calorie restriction on carbohydrate metabolism
Modified alternate‐day fasting regimens reduce cell proliferation rates to a similar extent as daily Calorie restriction in mice
Calorie restriction increases primordial follicle reserve in mature female chemotherapy-treated rats
Effects of Chronic Calorie restriction or Dietary Resveratrol Supplementation on Insulin Sensitivity Markers in a Primate, Microcebus murinus
Calorie restriction attenuates LPS-induced sickness behavior and shifts hypothalamic signaling pathways to an anti-inflammatory bias
Calorie intake during mammary development influences cancer risk: lasting inhibition of C3H/HeOu mammary tumorigenesis by peripubertal Calorie restriction
Calorie restriction: progress during mid-2005-mid-2006
Adult-onset Calorie restriction delays the accumulation of mitochondrial enzyme abnormalities in aging rat kidney tubular epithelial cells
Differential effects of Calorie restriction on glomeruli and tubules of the remnant kidney
Life-long Calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space
Calorie restriction prevents the development of insulin resistance and impaired insulin signaling in skeletal muscle of ovariectomized rats
dSir2 mediates the increased spontaneous physical activity in flies on Calorie restriction
Calorie restriction and endurance exercise share potent anti-inflammatory function in adipose tissues in ameliorating diet-induced obesity and insulin …
Changes in IL-15 expression and death-receptor apoptotic signaling in rat gastrocnemius muscle with aging and life-long Calorie restriction
Regulation of immune function by Calorie restriction and cyclophosphamide treatment in lupus-prone NZB/NZW F1 mice
A strategy for identifying biomarkers of aging: further evaluation of hematology and blood chemistry data from a Calorie restriction study in rhesus monkeys
Similar metabolic responses to Calorie restriction in lean and obese Zucker rats
Calorie restriction may be neuroprotective in AD and PD
Potential therapeutic targets for neurodegenerative diseases: lessons learned from Calorie restriction
Anxiety-like behaviour in adult rats perinatally exposed to maternal Calorie restriction
Down-regulation of AMP-activated protein kinase by Calorie restriction in rat liver
Effects of low-fat diet, Calorie restriction, and running on lipoprotein subfraction concentrations in moderately overweight men
Calorie restriction induces a p53-independent delay of spontaneous carcinogenesis in p53-deficient and wild-type mice
Dietary Calorie restriction, DNA-repair and brain aging
Distinct effects of Calorie restriction on adipose tissue cytokine and angiogenesis profiles in obese and lean mice
Calorie restriction reduced blood pressure in obesity hypertensives by improvement of autonomic nerve activity and insulin sensitivity
Exercise training and Calorie restriction increase SREBP-1 expression and intramuscular triglyceride in skeletal muscle
SIRT1 and SIRT5 activity expression and behavioral responses to Calorie restriction
Sir-2.1 modulates ‘Calorie–restriction-mediated’prevention of neurodegeneration in Caenorhabditis elegans: implications for Parkinson’s disease
Effect of Calorie restriction on change in lacrimal gland with age
Androgen receptor messenger ribonucleic acid (mRNA) in the rat liver: changes in mRNA levels during maturation, aging, and Calorie restriction
Calorie restriction reduces psychological stress reactivity and its association with brain volume and microstructure in aged rhesus monkeys
Phenotypic effects of Calorie restriction and insulin-like growth factor-1 treatment on body composition and bone mineral density of C57BL/6 mice: implications for …
The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for Calorie restriction-mediated life span extension
Adaptive stress response in segmental progeria resembles long-lived dwarfism and Calorie restriction in mice
The influence of Calorie restriction during the Ramadan fast on serum fructosamine and the formation of beta hydroxybutirate in type 2 diabetes mellitus patients
Calorie restriction in nonhuman primates: implications for age-related disease risk
Calorie restriction decreases proinflammatory cytokines and polymeric Ig receptor expression in the submandibular glands of autoimmune prone (NZB× NZW) F1 mice
Calorie restriction from a young age preserves the functions of pancreatic β cells in aging rats
Effect of severe Calorie restriction on the lung in two strains of mice
Influence of sleep disruption and Calorie restriction on biological markers for depression
Effects of Calorie restriction and weight loss on glucose and insulin levels in obese humans.
Calorie restriction and late-onset Calorie restriction extend lifespan but do not alter protein storage in female grasshoppers
Exercise as a Calorie restriction mimetic: implications for improving healthy aging and longevity
Sirtuins and Calorie restriction
Multiple pathways regulating the Calorie restriction response in yeast
Modulation of white adipose tissue proteome by aging and Calorie restriction
Assessment of auditory function in rhesus monkeys (Macaca mulatta): effects of age and Calorie restriction
The effects of different percentages of dietary fat intake, exercise, and Calorie restriction on body composition and body weight in obese females
Changes in lipid distribution during aging and its modulation by Calorie restriction
Distinct effects of Calorie restriction and exercise on mammary gland gene expression in C57BL/6 mice
Aging and Calorie restriction modulate yeast redox state, oxidized protein removal, and the ubiquitin–proteasome system
Long-term Calorie restriction enhances baroreflex responsiveness in Fischer 344 rats
Mouse liver plasma membrane redox system activity is altered by aging and modulated by Calorie restriction
Dietary lipids and Calorie restriction affect mammary tumor incidence and gene expression in mouse mammary tumor virus/v-Ha-ras transgenic mice
Understanding pathways of Calorie restriction: a way to prevent cancer?
Modulation of gene expression of SMP-30 by LPS and Calorie restriction during aging process
Hepatic oxidative stress during aging: effects of 8% long-term Calorie restriction and lifelong exercise
Calorie restriction improves whole-body glucose disposal and insulin resistance in association with the increased adipocyte-specific GLUT4 expression in Otsuka …
A role for ΔFosB in Calorie restriction-induced metabolic changes
Calorie restriction increases muscle insulin action but not IRS-1-, IRS-2-, or phosphotyrosine-PI 3-kinase
The arcuate nucleus and neuropeptide Y contribute to the antitumorigenic effect of Calorie restriction
Calorie restriction and dwarf mice in gerontological research
Calorie restriction extends life span—but which Calories?
Effects of intermittent and chronic Calorie restriction on mammalian target of rapamycin (mTOR) and IGF-I signaling pathways in mammary fat pad tissues and …
Do Calorie restriction or alternate-day fasting regimens modulate adipose tissue physiology in a way that reduces chronic disease risk?
Influence of Calorie restriction on oncogene expression and DNA synthesis during liver regeneration.
Exercise training plus Calorie restriction causes synergistic protection against cognitive decline via up-regulation of BDNF in hippocampus of stroke-prone …
Effects of chronic vs. intermittent Calorie restriction on mammary tumor incidence and serum adiponectin and leptin levels in MMTV-TGF-α mice at different …
Common mechanisms for Calorie restriction and adenylyl cyclase type 5 knockout models of longevity
Increased life span due to Calorie restriction in respiratory-deficient yeast
Combined effects of short-term Calorie restriction and exercise on insulin action in normal rats
Modulation of cutaneous aging with Calorie restriction in Fischer 344 rats: a histological study
Effects of Calorie restriction on the zebrafish liver proteome
Modulation of oxidative phosphorylation machinery signifies a prime mode of anti-ageing mechanism of Calorie restriction in male rat liver mitochondria
Calorie restriction increases the ratio of phosphatidylinositol 3-kinase catalytic to regulatory subunits in rat skeletal muscle
cDNA expression arrays reveal incomplete reversal of age-related changes in gene expression by Calorie restriction
Calorie restriction enhances insulin-stimulated glucose uptake and Akt phosphorylation in both fast-twitch and slow-twitch skeletal muscle of 24-month-old rats
Differential effects of protein-Calorie restriction and subsequent repletion on neuronal and nonneuronal components of cerebral cortex in newborn rats
Effects of Calorie restriction on immunologic functions and development of autoimmune disease in NZB mice
Impact of aging and life‐long Calorie restriction on expression of apoptosis‐related genes in male F344 rat liver
Transport of thyroxine into cultured hepatocytes: effects of mild non‐thyroidal illness and Calorie restriction in obese subjects
Lack of direct effect of moderate hyperleptinemia to improve endothelial function in lean rat aorta: role of Calorie restriction
Identification of potential Calorie restriction-mimicking yeast mutants with increased mitochondrial respiratory chain and nitric oxide levels
Calorie restriction and obesity under the regulation of SIRT1
It’s never too late: Calorie restriction is effective in older mammals
Effects of cystine and Calorie restriction on the incidence of spontaneous pulmonary tumors in strain A mice
Chronobiological features of the immune system. Effect of Calorie restriction
Effect of nitrogen and Calorie restriction on protein synthesis in the rat
Effects of Calorie restriction on reproductive and adrenal systems in Japanese quail: are responses similar to mammals, particularly primates?
Metabolic aspects of Calorie restriction: hypohydration effects on body weight and blood parameters.
Development of Calorie restriction mimetics as therapeutics for obesity, diabetes, inflammatory and neurodegenerative diseases
Revealing system-level correlations between aging and Calorie restriction using a mouse transcriptome
Effects of FTO Genotype on Weight Loss and Metabolic Risk Factors in Response to Calorie restriction Among Japanese Women
Reduction of circulating immune complexes by Calorie restriction in (NZB× NZW) F1 mice
Calorie restriction in the rotifer Brachionus plicatilis enhances hypoxia tolerance in association with the increased mRNA levels of glycolytic enzymes
Calorie restriction of a high-carbohydrate diet elevates the threshold of PTZ-induced seizures to values equal to those seen with a ketogenic diet
Plasma levels and adipose tissue messenger ribonucleic acid expression of retinol-binding protein 4 are reduced during Calorie restriction in obese subjects but are …
Effects of Calorie restriction on the expression of manganese superoxide dismutase and catalase under oxidative stress conditions in the rotifer Brachionus plicatilis
24‐hour changes in ACTH, corticosterone, growth hormone, and leptin levels in young male rats subjected to Calorie restriction
The effect of Calorie restriction on growth and development in silkworm, Bombyx mori
Calorie restriction (CR) reduces age-dependent decline of non-homologous end joining (NHEJ) activity in rat tissues
Effects of Calorie restriction and aging on the expression of antioxidant enzymes and ubiquitin in the liver of Emory mice
EVALUATION OF PROTEIN IN FOODS: XII. EFFECTS OF Calorie restriction
Aging effect on myeloperoxidase in rat kidney and its modulation by Calorie restriction
Aging in male primates: reproductive decline, effects of Calorie restriction and future research potential
At the crossroad of lifespan, Calorie restriction, chromatin and disease: meeting on sirtuins
Calorie restriction modulates hippocampal NMDA receptors in diet-induced obese rats
Dietary Calorie restriction in Mice Induces Carbamyl Phosphate Synthetase I Gene Transcription Tissue Specifically (∗)
Using PDE inhibitors to harness the benefits of Calorie restriction: lessons from resveratrol
Calorie restriction influences cell cycle protein expression and DNA synthesis during liver regeneration
Calorie restriction modulates lymphocyte subset phenotype and increases apoptosis in MRLlpr mice
Calorie restriction modulates age-dependent changes in the retinas of Brown Norway rats
Aging, Calorie restriction and ubiquitin-dependent proteolysis in the livers of Emory mice
Hormesis as a mechanism for the anti-aging effects of Calorie restriction
Different gene expression of skin tissues between mice with weight controlled by either Calorie restriction or physical exercise
Protein Calorie restriction affects nonhepatic IGF-I production and the lymphoid system: studies using the liver-specific IGF-I gene-deleted mouse model
Calorie restriction delays the crescentic glomerulonephritis of SCG/Kj mice
Influences of Calorie restriction and age on energy expenditure in the rhesus monkey
Identification of genes differentially expressed by Calorie restriction in the rotifer (Brachionus plicatilis)
A transgenic dwarf rat model as a tool for the study of Calorie restriction and aging
Calorie restriction delays age‐dependent loss in androgen responsiveness of the rat liver1
Conjectures on some curious connections among social status, Calorie restriction, hunger, fatness, and longevity
Relationship between Calorie restriction and the biological clock: lessons from long-lived transgenic mice
Calorie restriction: effect on growth of human tumors heterotransplanted in nude mice
Genetic reduction of insulin-like growth factor-1 mimics the anticancer effects of Calorie restriction on cyclooxygenase-2–driven pancreatic neoplasia
Effects of Calorie restriction on thymocyte growth, death and maturation
Effect of Calorie restriction on skeletal muscle and liver insulin binding in growing rat
Factors that affect Calorie-sensitive and Calorie-insensitive reduction in blood pressure during short-term Calorie restriction in overweight hypertensive women
Suppression of experimental autoimmune uveoretinitis by dietary Calorie restriction
The social behavior of male rats administered an adult-onset Calorie restriction regimen
Alterations in male sexual behaviour, attractiveness and testosterone levels induced by an adult-onset Calorie restriction regimen
The influence of protein-Calorie versus Calorie restriction on the body composition and cellular growth of muscle and liver in weanling rats.
Preventing the Calorie restriction-induced increase in insulin-stimulated Akt2 phosphorylation eliminates Calorie restriction‘s effect on glucose uptake in …
Dietary Calorie restriction in the Emory mouse: effects on lifespan, eye lens cataract prevalence and progression, levels of ascorbate, glutathione, glucose, and …
What you should know about Calorie restriction
Can alginate-based preloads increase weight loss beyond Calorie restriction? A pilot study in obese individuals
Effects of mild Calorie restriction on reproduction, plasma parameters and hepatic gene expression in mice with altered GH/IGF-I axis
Insulin signaling cascade in the hearts of long-lived growth hormone receptor knockout mice: effects of Calorie restriction
Calorie restriction and Skeletal Mass in Rhesus Monkeys (Macaca mulatta) Evidence for an Effect Mediated Through Changes in Body Size
The anti-tumor effects of Calorie restriction are correlated with reduced oxidative stress in ENU-induced gliomas
Calorie restriction inhibits sympathetic nerve activity via anti-oxidant effect in the rostral ventrolateral medulla of obesity-induced hypertensive rats
Calorie restriction increases insulin-stimulated tyrosine phosphorylation of insulin receptor and insulin receptor substrate-1 in rat skeletal muscle.
Development of a bioassay to screen for chemicals mimicking the anti-aging effects of Calorie restriction
Calorie restriction and spontaneous hepatic tumors in C3H/He mice.
The benefits of Calorie restriction and Calorie restriction mimetics as related to the eye
Long‐term effects of Calorie or protein restriction on serum IGF‐1 and IGFBP‐3 concentration in humans
Approach of evolutionary theories of ageing, stress, senescence-like phenotypes, Calorie restriction and hormesis from the view point of far-from-equilibrium …
Calorie restriction alters physical performance but not cognition in two models of altered neuroendocrine signaling
Chronic Calorie restriction alters glycogen metabolism in rhesus monkeys
Protein Calorie restriction has opposite effects on glucose metabolism and insulin gene expression in fetal and adult rat endocrine pancreas
Molecular inflammation as an underlying mechanism of aging: the anti-inflammatory action of Calorie restriction
Mild Calorie restriction does not affect testosterone levels and testicular gene expression in mutant mice
Opposing effects of age and Calorie restriction on molecular determinants of myocardial ischemic tolerance
Age-related decline in striatal volume in rhesus monkeys: assessment of long-term Calorie restriction
Neuroendocrine-immune correlates of circadian physiology: studies in experimental models of arthritis, ethanol feeding, aging, social isolation, and Calorie restriction
Calorie restriction, stress and the ubiquitin-dependent pathway in mouse livers
Downregulation of Grb2 contributes to the insulin-sensitizing effect of Calorie restriction
Radiation-induced myeloid leukemia in mice under Calorie restriction.
Locomotor activity in female rhesus monkeys: assessment of age and Calorie restriction effects
Calorie restriction reduces ulcerative dermatitis and infection-related mortality in p53-deficient and wild-type mice
Effects of moderate Calorie restriction on testosterone production and semen characteristics in young rhesus macaques (Macaca mulatta)
The influence of dietary lipid composition on skeletal muscle mitochondria from mice following 1 month of Calorie restriction
Calorie restriction in the filamentous fungus Podospora anserina
… and insulin‐like growth factor binding protein‐1 to an oral glucose tolerance test in obese women with polycystic ovary syndrome before and after Calorie restriction
NO link between Calorie restriction and mitochondria
Calorie restriction in nonhuman and human primates
Calorie restriction, Post‐reproductive Life Span, and Programmed Aging: A Plea for Rigor
Rapid onset of gene expression in lung, supportive of formation of alveolar septa, induced by refeeding mice after Calorie restriction
Effects of severe Calorie restriction on thymic factor activity and lymphocyte stimulation response in rats
Physical activity, dietary Calorie restriction, and cancer
Plant “Polyphenolic” Small Molecules Can Induce a Calorie restriction‐Mimetic Life‐Span extension by Activating Sirtuins: Will “Polyphenols” Someday Be Used as …
A difference between the effects of dietary Calorie restriction on the estrous cycle and on the 24-hour adrenal cortical cycle in rodents
Long‐term evaluation of thyroidal response to partial Calorie restriction in obesity
Calorie restriction minimizes activation of insulin signaling in response to glucose: potential involvement of the growth hormone-insulin-like growth factor 1 axis
Alternate day Calorie restriction improves systemic inflammation in a mouse model of sepsis induced by cecal ligation and puncture
Hepatic metabolites and cofactors in riboflavin deficiency and Calorie restriction
… of mitogenic responses, lymphocyte subset populations and amino acid content in submaxillary lymph nodes of growing male rats subjected to Calorie restriction
Impact of moderate Calorie restriction on the reproductive neuroendocrine axis of male rhesus macaques
Inhibition of H2O2‐induced apoptosis of lymphocytes by Calorie restriction during aging
Oxaloacetic acid supplementation as a mimic of Calorie restriction
AgingDB: A database for oxidative stress and Calorie restriction in the study of aging
Superimposition of postnatal Calorie restriction protects the aging male intrauterine growth-restricted offspring from metabolic maladaptations
Effects of aging and Calorie restriction on rat skeletal muscle glycogen synthase and glycogen phosphorylase
Calorie restriction to retard aging and increase longevity
Attenuation of bleomycin-induced Hprt mutant frequency in female and male rats by Calorie restriction
Effect of Calorie restriction on liver and kidney glutathione in aging Emory mice
Calorie restriction prevents the occlusive coronary vascular disease of autoimmune (NZW x BXSB) F1 mice
HPA and sympathoadrenal activity of adult rats perinatally exposed to maternal mild Calorie restriction
Calorie restriction initiated at middle age improved glucose tolerance without affecting age-related impairments of insulin signaling in rat skeletal muscle
Symposium: Calorie restriction: effects on body composition, insulin signaling and aging
Effects of dehydroepiandrosterone and Calorie restriction on the Bcl-2/Bax-mediated apoptotic pathway in p53-deficient mice
Biological effects of Calorie restriction: implications for modification of human aging
Effects of Calorie restriction on SIRT1 expression in liver of nonalcoholic fatty liver disease: experiment with rats
Metabolic aspects of Calorie restriction: nitrogen and mineral balances and vitamin excretion
Calorie restriction causes healthy life span extension in the filamentous fungus Podospora anserina
Role of insulin and growth hormone/insulin-like growth factor-I signaling in lifespan extension: rodent longevity models for studying aging and Calorie restriction
Identifying the genes and genetic interrelationships underlying the impact of Calorie restriction on maximum lifespan: an artificial intelligence-based approach
The influence of estrogen on cancer incidence and adrenal changes in ovariectomized mice on Calorie restriction.
Effects of aging and Calorie restriction of Fischer 344 rats on hepatocellular response to proliferative signals
Calorie restriction decreases platelet‐derived growth factor (PDGF)‐A and thrombin receptor mRNA expression in autoimmune murine lupus nephritis
Effects of Calorie–restriction on the course of Trypanosoma cruzi infection
Calorie restriction as a potent anti-aging intervention: Modulation of oxidative stress
Dietary Calorie restriction does not affect the levels of protein elongation factors in rat livers during ageing
Calorie restriction suppresses subgenomic mink cytopathic focus-forming murine leukemia virus transcription and frequency of genomic expression while impairing …
Improved insulin sensitivity with Calorie restriction does not require reduced JNK1/2, p38, or ERK1/2 phosphorylation in skeletal muscle of 9-month-old rats
Method for estimating rate of fat loss during treatment of obesity by Calorie restriction
Dichotomous responses of inter and postprandial hyperglycaemia to short‐term Calorie restriction in patients with type 2 diabetes
Calorie restriction and iopanoic acid effects on thyroid hormone metabolism
Proteomic analysis of proteins associated with cellular senescence by Calorie restriction in mesenchymal stem cells
Effect of Calorie restriction on mortality kinetics in inbred strains of mice following 7, 12-dimethylbenz [a] anthracene treatment
mRNA-Seq reveals complex patterns of gene regulation and expression in the mouse skeletal muscle transcriptome associated with Calorie restriction
Effects of protein-Calorie restriction on mechanical function of hypertrophied cardiac muscle
The effects of aging and Calorie restriction on plasma nutrient levels in male and female Emory mice
The mitochondrial plasmid pAL2-1 reduces Calorie restriction mediated life span extension in the filamentous fungus Podospora anserina
Calorie restriction increases Fas/Fas-ligand expression and apoptosis in murine splenic lymphocytes
The effect of Calorie restriction on serum thyroid hormone binding proteins and free hormone in obese patients
Calorie restriction mimetics: examples and mode of action
Effects of mild Calorie restriction and high-intensity interval walking in middle-aged and older overweight Japanese
Calorie restriction decreases microalbuminuria associated with aging in barrier-raised Fischer 344 rats
Adult-onset Calorie restriction attenuates kainic acid excitotoxicity in the rat hippocampal slice
Middle-aged C57BL/6 mice have impaired responses to leptin that are not improved by Calorie restriction
24-hour changes in circulating prolactin, follicle-stimulating hormone, luteinizing hormone, and testosterone in young male rats subjected to Calorie restriction
Enhancement of age-related increases in DNA I-compound levels by Calorie restriction: comparison of male BN and F-344 rats
Calorie restriction modulates redox-sensitive AP-1 during the aging process
Calorie restriction increases light-dependent photoreceptor cell loss in the neural retina of Fischer 344 rats
Study on the lipid composition of aging fischer‐344 rat lymphoid cells: Effect of long‐term Calorie restriction
… of acute inhibition of fatty acid oxidation on latency to seizure and concentrations of β hydroxybutyrate in plasma of rats maintained on Calorie restriction and/or the …
Calorie restriction in mice overexpressing UCP3: evidence that prior mitochondrial uncoupling alters response
The Calorie–restriction experiment
Effects of age and Calorie restriction on tryptophan nitration, protein content, and activity of succinyl-CoA: 3-ketoacid CoA transferase in rat kidney mitochondria
Body growth, mitochondrial enzymatic capacities and aspects of the antioxidant system and redox balance under Calorie restriction in young turbot (Scophthalmus …
Metabolizable energy intake during long-term Calorie restriction in rhesus monkeys
Calorie restriction up-regulates iron and copper transport genes in Saccharomyces cerevisiae
Melatonin fails to modulate immune parameters influenced by Calorie restriction in aging Fischer 344 rats
The redox-sensitive DNA binding sites responsible for age-related downregulation of SMP30 by ERK pathway and reversal by Calorie restriction
Comparison of the effects of 20 days and 15 months of Calorie restriction on male Fischer 344 rats
In Silico Drug Screen in Mouse Liver Identifies Candidate Calorie restriction Mimetics
The decline in plasma leptin in response to Calorie restriction predicts the effects of adjunctive leptin treatment on body weight in humans
Calorie restriction test
Depletion of linoleate induced by weight cycling is independent of extent of Calorie restriction
Relationship between protein O‐linked glycosylation and insulin‐stimulated glucose transport in rat skeletal muscle following Calorie restriction or exposure to O‐(2 …
Possible mechanisms through which dietary lipids, Calorie restriction, and exercise modulate breast cancer
Effects of gradation in protein-Calorie restriction on the hypothalo-pituitary-gonadal axis in young domestic fowl
Blocking Dopamine D2 Receptors by Haloperidol Curtails the Beneficial Impact of Calorie restriction on the Metabolic Phenotype of High‐Fat Diet Induced Obese …
Calorie restriction modulates Th-1 and Th-2 cytokine-induced immunoglobulin secretion in young and old C57BL/6 cultured submandibular glands
Lesions of glucose-responsive neurons impair synchronizing effects of Calorie restriction in mice
Blood pressure is reduced by short-time Calorie restriction in overweight hypertensive women with a constant intake of sodium and potassium
Early hypothalamic response to age-dependent gene expression by Calorie restriction
Weight maintenance in humans. Could it mimic Calorie restriction of animal models?
Klotho expression is induced by Calorie restriction in adult male rats
Effect of protein-Calorie restriction on brain amino acid pool in neonatal rats
Thiamin, riboflavin, and pyridoxine excretion during acute starvation and Calorie restriction
Long-term Calorie restriction protects rat pituitary growth hormone-releasing hormone binding sites from age-related alterations
Calorie restriction modifies the delayed-type hypersensitivity response to the hapten trinitrobenzenesulfonic acid and to hapten-modified syngeneic spleen cells
In vitro simulation of Calorie restriction-induced decline in glucose and insulin leads to increased insulin-stimulated glucose transport in rat skeletal muscle
Food toxicity contributes to the beneficial effects of Calorie restriction
Acute stress response modified by modest inhibition of growth hormone axis: a potential machinery of the anti-aging effect of Calorie restriction
Mammary and submandibular gland epidermal growth factor expression is reduced by Calorie restriction
Effects of adult onset mild Calorie restriction on weight of reproductive organs, plasma parameters and gene expression in male mice
Weight loss and Calorie restriction at 50% fasting rate
Short-term Calorie restriction in early life attenuates the development of proteinuria but not glucose intolerance in type 2 diabetic OLETF rats
Atypical hematological response to combined Calorie restriction and chronic hypoxia in Biosphere 2 crew: a possible link to latent features of hibernation capacity
The impact of Calorie restriction on mammary cancer development in an experimental model
Could Calorie restriction increase longevity in humans?
Comparative proteomic analysis of Bombyx mori hemolymph and fat body after Calorie restriction.
Effects of Calorie restriction on chromosomal stability in rhesus monkeys (Macaca mulatta)
Alterations in the rate of fetal and placental development as a consequence of early maternal protein/Calorie restriction
Effects of Aging and Long‐Term Calorie restriction on DHEA and DHEA Sulfate in Rhesus Monkeys
The effects of Calorie restriction on operant-responding for alcohol in the alcohol preferring (iP) rat
Calorie restriction and longevity: fast and loose?
The antihypertensive effect of Calorie restriction in obese adolescents: dissociation of effects on erythrocyte countertransport and cotransport.
Calorie restriction: a potent mechanistic solution to the oxygen paradox
Influence of genotype and protein-Calorie restriction upon RSV-induced tumors in chickens
The effects of protein and Calorie restriction on tissue nitrogen content and protein catabolism
Calorie restriction in mice does not affect LDL reverse cholesterol transport in vivo
Effects of short-term mild Calorie restriction diet and renutrition with ruminant milks on leptin levels and other metabolic parameters in mice
Opposite effects of metabolic syndrome and Calorie restriction on thrombotic disease: heads and tails of the same coin—resveratrol’s role
Network reconstruction reveals new links between aging and Calorie restriction in yeast
Calorie restriction initiated at a young age activates the Akt/PKCζ/λ-Glut4 pathway in rat white adipose tissue in an insulin-independent manner
Calorie restriction mimetics and aging
Effects of genetic polymorphism of uncoupling protein 2 on body fat and Calorie restriction‐induced changes1
Elongation Factor 2-Specific Calcium-and Calmodulin-Dependent Protein Kinase III Activity in Rat Livers Varies with Age and Calorie restriction
Age-and Calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans
Effect of Calorie restriction supplemented with genistein on serum levels of glucose, lipid profile and inflammatory markers (resistin and hsCRP) in obese rats.
… the changes in gene profiles regulating the amelioration of age-related oxidative damages in kidney tissue of rats by the intervention of adult-onset Calorie restriction
Beneficial effects of weight loss associated with moderate Calorie/carbohydrate restriction, and increased proportional intake of protein and unsaturated fat on serum …
A transgenic mini rat strain as a tool for studying aging and Calorie restriction
The influence of acute, late-life Calorie restriction on whole body energy metabolism in p66Shc (−/−) mice
Effect of Calorie restriction on the fate of hyperplastic liver nodules induced by concurrent administration of lasiocarpine and thioacetamide
Calorie restriction increases serum parathyroid hormone and decreases serum calcitonin levels in patients with maturity onset diabetes mellitus
Effects of protein-Calorie restriction on the immune response to skin allografts in the rat.
… in body weight and reduction in blood pressure and improvement of glucose and lipid metabolism induced by short-term Calorie restriction in overweight hypertensive …
The effects of Calorie restriction olfactory cues on conspecific anxiety-like behaviour
Alterations in hepatic glucose and energy metabolism as a result of Calorie and carbohydrate restriction
Pubertal adiposity after fetal growth restraint: toward a Calorie restriction mimetic approach
Aging and the effect of Calorie restriction in rhesus monkeys
Calorie restriction in nonhuman primates: Impact on aging, disease, and frailty
Oxidative stress and Calorie restriction in aging
Protein intake during aggressive Calorie restriction in obesity determines growth hormone response to growth hormone‐releasing hormone after weight loss
In vivo study of mitochondrial oxidation in obese patients treated by means of Calorie restriction
Molecular mechanisms of longevity regulation and Calorie restriction
Effects of Calorie restriction and ω-3 dietary fat on aging in short-and long-lived rodents
Can Calorie restriction prolong life?
Will Calorie restriction stave off age-related brain dysfunction, specifically to learning and memory? A review and critique of the rodent literature
The effect of dietary protein‐Calorie restriction on the renal elimination of cimetidine
Divergent regulation of adipose tissue metabolism by Calorie restriction and inhibition of growth hormone signaling
… responses of circulating prolactin, GH, and ACTH levels and distribution and activity of submaxillary lymph node lymphocytes to Calorie restriction in male Lewis and …
Models of longevity (Calorie restriction and AC5 KO): result of three bad hypotheses
Calorie restriction reduces the incidence of radiation-induced myeloid leukaemia.
Changes in human body composition during Calorie restriction with two levels of protein
Accommodative function in rhesus monkeys: effects of aging and Calorie restriction
Molecular Mechanisms of Extending lifespan by Calorie restriction [J]
Calorie restriction as a probe for understanding neuroendocrine involvement in the aging processes
Long-term protein and Calorie restriction: alterations in nucleic acid levels of organs of male rats
Calorie restriction counteracts the impairment of adipocyte insulin-stimulated lipogenesis in aging rats, but not that induced by dexamethasone treatment
Inhibition of intracellular peroxides and apoptosis of lymphocytes in lupus-prone B/W mice by dietary n-6 and n-3 lipids with Calorie restriction
Effects of Calorie restriction on the age-dependent accumulation of mutations in the small intestine of lacZ-transgenic mice
Calorie restriction and Cancer: An Update
The superimposition of Calorie restriction on protein deficiency-effects on liver, small intestine and pancreas of young albino rats.
Life extension Properties of Superoxide Dismutase Mimics Arise from “Calorie restriction”
Dietary n-3 fatty acids and Calorie restriction in autoimmune disease: influence in different immune compartments
Dissociated response of plasma albumin and transferrin to protein-Calorie restriction in squirrel monkeys (Saimiri sciureus)
Calorie restriction reduces MMP-2 activity and retards age-associated aortic restructuring in rats
Molecular mechanisms of mitochondrial proliferation induced by Calorie restriction
Reversing the Negative Genomic Effects of Aging with Short-Term Calorie restriction
Effect of dietary Calorie and fat restriction on mammary tumor growth and hepatic as well as tumor glutathione in rats
Gut adaptation to chronic Calorie restriction in aged mice.
When less is adequate: Protein and Calorie restriction boosts immunity and possibly, longevity–but how and why?
The effect of aerobic training with or without Calorie restriction on lipid profile in adult obese females
Longevity & Calorie restriction
Effect of Calorie restriction on the development of virus induced leukaemia in mice
Effect of protein and Calorie restriction on the cytochrome P-450 isozyme (P-450 IID6) activity in rats
Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from Calorie intake
Calorie restriction the Fountain of Youth
Selective dietary restriction of protein and Calorie intakes prevents spontaneous proteinuria in male MWF rats.
Conclusion: human Calorie restriction and anti-aging therapy
Interaction of growth hormone and Calorie restriction
Effect of exercise and Calorie restriction on ambulatory blood pressure in overweight, sedentary males: A time series analysis
Long-Term Calorie restriction increases SIRT1 expression and Inhibits Vascular Senescence in Mice
Effects of moderate Calorie restriction on ovarian function and decline in rhesus monkeys
Modest inhibition of the growth hormone axis does not affect mitochondrial reactive oxygen species generation or redox state, unlike Calorie restriction
Dietary Energy Balance, Calorie restriction, and Cancer Prevention
Calorie restriction, Exercise, and Colon Cancer Prevention: A Mechanistic Perspective
Symposium: Calorie restriction: effects on body composition, insulin signaling and aging
Evaluation of Mood States During a Weight Loss Program (Calorie restriction) in Overweight Volunteers
24-Hour rhythms of splenic mitogenic responses, lymphocyte subset populations and interferon γ release after Calorie restriction or social isolation of rats
Calorie restriction for optimal cardiovascular aging: the weight of evidence
Bile acids extend longevity beyond Calorie restriction
AV Everitt, SIS Rattan, DG Le Couteur, R. de Cabo (eds): Calorie restriction, aging and longevity
… of Growth Hormone–Insulin-like Growth Factor-I or the Insulin Axis in Aging and Longevity: Special Reference to a Transgenic Dwarf Rat Strain and Calorie restriction
Investigations of Altered Proteome Dynamics in Calorie restriction, Insulin Resistance and Type 2 Diabetes
Moderate Calorie restriction activates autophagy during tumor growth suppression
Abstract B4: Calorie restriction prevents the development of pancreatic cancer in Kras; Pdx-1Cre mice
Calorie restriction affects brain glutathione metabolism in normal and long-living mice
Calorie restriction as a means to control skeletal muscle stiffness in aged rats
The effect of Calorie restriction and exercise on the estrous cycle and bone mineral density of nonovariectomized rats
The effects of aging and Calorie restriction on whole-body and mitochondrial energetics
Antiobese and hypolipidemic effects of platycodin saponins in diet-induced obese rats: evidences for lipase inhibition and Calorie intake restriction
The effect of Calorie restriction on the expression of liver’s gluconeogenesis genes of rats fed a high fat diet
Effects of dietary Calorie restriction or exercise on the PI3K and Ras signaling pathways in the skin of mice. VOLUME 282 (2007) PAGES 28025-28035
Calorie restriction enhances longevity without reducing lifetime fecundity or glucose titers in female lubber grasshoppers
Influence of Calorie restriction on insulin signalling and glucose transport in skeletal muscle of rats
Effect of protein-Calorie restriction during pregnancy in rats, on the activity of glycolytic enzymes in the placenta
A transgenic dwarf rat strain as a tool for the study of immunosenescence in aging rats and the effect of Calorie restriction
Abstract A94: effects of different modes of Calorie restriction on mammalian target of rapamycin (mTOR) and IGF-I signaling pathways in mammary fat pads and tumors