– Phlorizin is a natural compound found in fruit trees that has been used for over 150 years in pharmaceutical and physiological research.
– Its main pharmacological action is to produce renal glycosuria and block intestinal glucose absorption.
– Phlorizin has played a significant role in the history of diabetes mellitus and has been used as a tool to study renal function.
– It inhibits the sodium-glucose symporters (SGLTs) located in the proximal renal tubule and mucosa of the small intestine.
– Phlorizin has potential uses in the treatment of diabetes, obesity, and stress hyperglycemia.
– It improves insulin sensitivity and normalizes blood glucose levels in diabetic animals.
– Phlorizin has antioxidant properties and may have potential cardiovascular benefits.
– It has been studied for its potential use in the treatment of various conditions, including diabetes, cancer, and neurodegenerative diseases.

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   PHLORIZIN: a review

2. Correction of hyperglycemia with PHLORIZIN normalizes tissue sensitivity to insulin in diabetic rats.
3. On the identity between the small intestinal enzymes PHLORIZIN hydrolase and glycosylceramidase
4. Transcriptional regulation of the lactase-PHLORIZIN hydrolase gene by polymorphisms associated with adult-type hypolactasia
5. A method for preparing C-glycosides related to PHLORIZIN
6. Acute anti‐hyperglycaemic effects of an unripe apple preparation containing PHLORIZIN in healthy volunteers: a preliminary study
7. Evaluation of the anti-inflammatory effects of phloretin and PHLORIZIN in lipopolysaccharide-stimulated mouse macrophages
8. Reevaluation of renal tubular glucose transport inhibition by PHLORIZIN analogs
9. PHLORIZIN prevents glomerular hyperfiltration but not hypertrophy in diabetic rats
10. The action of PHLORIZIN on the excretion of glucose, xylose, sucrose, creatinine and urea by man
11. Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase PHLORIZIN hydrolase
12. Effects of PHLORIZIN and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia
13. Probing the antioxidant potential of phloretin and PHLORIZIN through a computational investigation
14. Complete primary structure of human and rabbit lactase‐PHLORIZIN hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme.
15. Simultaneous separation and purification of total polyphenols, chlorogenic acid and PHLORIZIN from thinned young apples
16. The human lactase‐PHLORIZIN hydrolase gene is located on chromosome 2
17. Regulation of lactase–PHLORIZIN hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2
18. PHLORIZIN-like effect of Fraxinus excelsior in normal and diabetic rats
19. Energy-dependence of PHLORIZIN binding to isolated renal microvillus membranes
20. Biosynthesis and maturation of lactase-PHLORIZIN hydrolase in the human small intestinal epithelial cells
21. Insulin Sensitivity-Enhancing Activity of PHLORIZIN Is Associated with Lipopolysaccharide Decrease and Gut Microbiota Changes in Obese and Type 2 Diabetes (db/db …
22. PHLORIZIN, a competitive inhibitor of glucose transport, facilitates memory storage in mice
23. Hypothesis for the interaction of PHLORIZIN and phloretin with membrane carriers for sugars
24. Normalization of blood glucose in diabetic rats with PHLORIZIN treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose …
25. Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by PHLORIZIN during ischemia-reperfusion injury in mice
26. Effect of PHLORIZIN on SGLT2 expression in the kidney of diabetic rats.
27. Purification and characterisation of amphiphilic lactase/PHLORIZIN hydrolase from human small intestine
28. PHLORIZIN as a probe of the small-intestinal Na+, D-glucose cotransporter. A model
29. Fourth ventricular PHLORIZIN dissociates feeding from hyperglycemia in rats
30. Isolation and characterization of a novel glycosyltransferase that converts phloretin to PHLORIZIN, a potent antioxidant in apple
31. Competitive inhibition of intestinal glucose transport by PHLORIZIN analogs
32. Structure of the chromosomal gene and cDNAs coding for lactase-PHLORIZIN hydrolase in humans with adult-type hypolactasia or persistence of lactase.
33. Renal tubular reabsorption of acetoacetate, inorganic sulfate and inorganic phosphate in the dog as affected by glucose and PHLORIZIN
34. Beneficial effects of PHLORIZIN on diabetic nephropathy in diabetic db/db mice
35. Use of PHLORIZIN binding to demonstrate induction of intestinal glucose transporters
36. On the mode of action of PHLORIZIN as an antimalarial agent in in vitro cultures of Plasmodium falciparum
37. Investigation of the protective effects of PHLORIZIN on diabetic cardiomyopathy in db/db mice by quantitative proteomics
38. Further characterization of intestinal lactase/PHLORIZIN hydrolase
39. PHLORIZIN enhancement of memory in rats and mice
40. Lactose intolerance and the genetic regulation of intestinal lactase‐PHLORIZIN hydrolase
41. PHLORIZIN supplementation attenuates obesity, inflammation, and hyperglycemia in diet-induced obese mice fed a high-fat diet
42. Comparative oral and intravenous pharmacokinetics of PHLORIZIN in rats having type 2 diabetes and in normal rats based on phase II metabolism
43. Feeding response of Aphis pomi, Myzus persicae, and Amphorophora agathonica to PHLORIZIN
44. Intestinal lactase-PHLORIZIN hydrolase (LPH): the two catalytic sites; the role of the pancreas in pro-LPH maturation
45. Inhibition of glucose transport into brain by PHLORIZIN, phloretin and glucose analogues
46. Interaction between the homeodomain proteins Cdx2 and HNF1α mediates expression of the lactase-PHLORIZIN hydrolase gene
47. Effects of hyperglycemia on glucose transporters of the muscle: use of the renal glucose reabsorption inhibitor PHLORIZIN to control glycemia.
48. Inhibition of photophosphorylation by PHLORIZIN and closely related compounds
49. PHLORIZIN administration increases hepatic gluconeogenic enzyme mRNA abundance but not feed intake in late-lactation dairy cows
50. … Soluble N-Ethylmaleimide-Sensitive Factor Attachment Protein Receptors in Goto-Kakizaki Rats Is Partially Restored by PHLORIZIN Treatment and Accentuated by …
51. Apple PHLORIZIN attenuates oxidative stress in Drosophila melanogaster
52. Complex regulation of the lactase-PHLORIZIN hydrolase promoter by GATA-4
53. Protective effect of apple PHLORIZIN on hydrogen peroxide‐induced cell damage in HepG2 cells
54. Phloretin and PHLORIZIN promote lipolysis and inhibit inflammation in mouse 3 T 3‐L 1 cells and in macrophage‐adipocyte co‐cultures
55. Regional localization of the lactase‐PHLORIZIN hydrolase gene, LCT, to chromosome 2q21
56. Intestinal uptake of quercetin-3-glucoside in rats involves hydrolysis by lactase PHLORIZIN hydrolase
57. … sites in intestinal lactase-PHLORIZIN hydrolase. Comparison with sucrase-isomaltase and with other glycosidases, the membrane anchor of lactase-PHLORIZIN …
58. Correction of chronic hyperglycemia with vanadate, but not with PHLORIZIN, normalizes in vivo glycogen repletion and in vitro glycogen synthase activity in diabetic …
59. PHLORIZIN recognition in a C-terminal fragment of SGLT1 studied by tryptophan scanning and affinity labeling
60. Dietary PHLORIZIN enhances osteoblastogenic bone formation through enhancing β-catenin activity via GSK-3β inhibition in a model of senile osteoporosis
61. PHLORIZIN pretreatment reduces acute renal toxicity in a mouse model for diabetic nephropathy
62. Molecular and cellular aspects and regulation of intestinal lactase-PHLORIZIN hydrolase
63. Dietary Supplementation of Apple PHLORIZIN Attenuates the Redox State Related to Gut Microbiota Homeostasis in C57BL/6J Mice Fed with a High-Fat Diet
64. Coordinate expression of lactase-PHLORIZIN hydrolase mRNA and enzyme levels in rat intestine during development.
65. Na+‐Dependent and PHLORIZIN‐Inhibitable Transport of Glucose and Cycasin in Brain Endothelial Cells
66. … β‐glucosidase gene bglA of Clostridium thermocellum Sequence analysis reveals a superfamily of cellulases and β‐glycosidases including human lactase/PHLORIZIN …
67. Assignment of the locus for congenital lactase deficiency to 2q21, in the vicinity of but separate from the lactase-PHLORIZIN hydrolase gene
68. Renal excretion of PHLORIZIN and PHLORIZIN glucuronide
69. Enzymatic properties of rat lactase-PHLORIZIN hydrolase
70. Comparative effects of PHLORIZIN and phloretin on glucose transport in the cat kidney
71. Probing the conformation of the sugar transport inhibitor PHLORIZIN by 2D-NMR, molecular dynamics studies, and pharmacophore analysis
72. Effects of PHLORIZIN on vascular complications in diabetes db/db mice
73. Expression of a full-length cDNA coding for human intestinal lactase-PHLORIZIN hydrolase reveals an uncleaved, enzymatically active, and transport-competent protein
74. PHLORIZIN induced autophagocytosis during hepatocytic glycogenolysis
75. PHLORIZIN-and 6-ketocholestanol-mediated antagonistic modulation of alamethicin activity in phospholipid planar membranes
76. d-Glucose-Recognition and PHLORIZIN-Binding Sites in Human Sodium/d-Glucose Cotransporter 1 (hSGLT1):  A Tryptophan Scanning Study
77. PHLORIZIN treatment of diabetic rats partially reverses the abnormal expression of genes involved in hepatic glucose metabolism
78. Studies on the mechanism of intestinal absorption of sugars VII. Phenylglycoside transport and its possible relationship to PHLORIZIN inhibition of the active transport of …
79. Effects of salbutamol and PHLORIZIN on acute pulmonary inflammation and disease severity in experimental sepsis
80. Purified PHLORIZIN from DocynIa Indica (Wall.) Decne by HSCCC, compared with whole extract, PHLORIZIN and non-PHLORIZIN fragment ameliorate obesity, insulin …
81. Enzymatic synthesis of PHLORIZIN fructosides
82. P38 and JNK signal pathways are involved in the regulation of PHLORIZIN against UVB‐induced skin damage
83. PHLORIZIN administration does not attenuate hypophagia induced by intraruminal propionate infusion in lactating dairy cattle
84. PHLORIZIN receptors in isolated kidney brush border membranes
85. Impact of O-glycosylation on the function of human intestinal lactase-PHLORIZIN hydrolase. Characterization of glycoforms varying in enzyme activity and …
86. Genotyping of the lactase-PHLORIZIN hydrolase− 13910 polymorphism by LightCycler PCR and implications for the diagnosis of lactose intolerance
87. Biosynthesis of intestinal microvillar proteins intracellular processing of lactase-PHLORIZIN hydrolase
88. Kinetics of Metabolism of Glucose, Propionate and CO2 in Steers as Affected by Injecting PHLORIZIN and Feeding Propionate
89. Biotransformation of PHLORIZIN by human intestinal flora and inhibition of biotransformation products on tyrosinase activity
90. Extracellular space estimation in rat kidney slices using C14 saccharides and PHLORIZIN
91. New insights into lactase and glycosylceramidase activities of rat lactase-PHLORIZIN hydrolase
92. The effects on renal activity of the oral administration of PHLORIZIN in man
93. The pro region of human intestinal lactase-PHLORIZIN hydrolase.
94. Competitive inhibition of PHLORIZIN binding by D-glucose and the influence of sodium: a study on isolated brush border membrane of rat kidney
95. Hydrolysis by lactase PHLORIZIN hydrolase is the first step in the uptake of daidzein glucosides by rat small intestine in vitro
96. Correlation between lactose absorption and the C/T-13910 and G/A-22018 mutations of the lactase-PHLORIZIN hydrolase (LCT) gene in adult-type hypolactasia
97. Inhibition of glucose absorption by PHLORIZIN affects intestinal functions in rats
98. HIGH-RESOLUTION RADIOAUTOGRAPHY OF PHLORIZIN-3H IN RINGS OF HAMSTER INTESTINE
99. AICAR and PHLORIZIN reverse the hypoglycemia-specific defect in glucagon secretion in the diabetic BB rat
100. Benzyl benzoates: New PHLORIZIN analogs as mushroom tyrosinase inhibitors
101. Effects of PHLORIZIN on metabolism and function of pancreatic β-cell
102. A novel intestinal trans-factor (NF-LPH1) interacts with the lactase-PHLORIZIN hydrolase promoter and co-varies with the enzymatic activity.
103. The prosequence of human lactase-PHLORIZIN hydrolase modulates the folding of the mature enzyme
104. Biosynthesis, glycosylation, and intracellular transport of intestinal lactase-PHLORIZIN hydrolase in rat.
105. Biogenesis of intestinal lactase-PHLORIZIN hydrolase in adults with lactose intolerance. Evidence for reduced biosynthesis and slowed-down maturation in enterocytes.
106. Differential mechanism‐based labeling and unequivocal activity assignment of the two active sites of intestinal lactase/PHLORIZIN hydrolase
107. The comparative effects of some PHLORIZIN analogs on the renal reabsorption of glucose
108. … comparative study on the metabolism of Epimedium koreanum Nakai-prenylated flavonoids in rats by an intestinal enzyme (lactase PHLORIZIN hydrolase) and intestinal …
109. Effects of PHLORIZIN on diabetic retinopathy according to isobaric tags for relative and absolute quantification–based proteomics in db/db mice
110. Transcriptional regulation of pig lactase-PHLORIZIN hydrolase: involvement of HNF-1 and FREACs
111. Random, presumably hydrolytic, and lysosomal glycogenolysis in the livers of rats treated with PHLORIZIN and of newborn rats
112. Transmembrane disposition of the PHLORIZIN binding protein of intestinal brush borders
113. In vitro evaluation of relative inhibitory potency of PHLORIZIN and its congeners
114. Effect of PHLORIZIN on the osmotic behavior of mitochondria in isotonic sucrose
115. Some effects of PHLORIZIN on the metabolism of mitochondria
116. PHLORIZIN inhibition of hypothalamic necrosis induced by gold thioglucose
117. Two-step mechanism of PHLORIZIN binding to the SGLT1 protein in the kidney
118. High affinity PHLORIZIN receptor sites and their relation to the glucose transport mechanism in the proximal tubule of dog kidney
119. Inhibition of [3H] PHLORIZIN binding to isolated kidney brush border membranes by PHLORIZIN-like compounds
120. PHLORIZIN exerts direct protective effects on palmitic acid (PA)-induced endothelial dysfunction by activating the PI3K/AKT/eNOS signaling pathway and …
121. Comprehensive Transcriptome Analysis Revealed the Effects of the Light Quality, Light Intensity, and Photoperiod on PHLORIZIN Accumulation in Lithocarpus …
122. Additional N-glycosylation and its impact on the folding of intestinal lactase-PHLORIZIN hydrolase
123. Highly selective electrochemical determination of PHLORIZIN using square wave voltammetry at a boron-doped diamond electrode
124. A study of some effects of PHLORIZIN on the metabolism of kidney tissue in vitro
125. Characteristics of glucose-PHLORIZIN interactions in isolated proximal tubules
126. Dietary carbohydrates enhance lactase/PHLORIZIN hydrolase gene expression at a transcription level in rat jejunum
127. High affinity PHLORIZIN binding to the LLC-PK1 cells exhibits a sodium: PHLORIZIN stoichiometry of 2: 1.
128. Identification of PHLORIZIN binding domains in sodium-glucose cotransporter family: SGLT1 as a unique model system
129. Apple PHLORIZIN oxidation product 2 inhibits proliferation and differentiation of 3T3-L1 preadipocytes
130. Absorption of quercetin-3-glucoside and quercetin-4′-glucoside in the rat small intestine: the role of lactase PHLORIZIN hydrolase and the sodium-dependent glucose …
131. Effects of PHLORIZIN on glucose kinetics in the bovine
132. Effects of PHLORIZIN and acipimox on insulin resistance in STZ-diabetic rats
133. PHLORIZIN and Trilobatin, Sweet Dihydrochalcone-Glucosides from Leaves of Lithocarpus litseifolius (Hance) Rehd. (Fagaceae)
134. Evidence for biosynthesis of lactase-PHLORIZIN hydrolase as a single-chain high-molecular weight precursor
135. Some quantitative studies on PHLORIZIN inhibition of glucose transport in the kidney
136. Effect of PHLORIZIN on hepatic glucose output
137. Binding of PHLORIZIN to the Isolated C-Terminal Extramembranous Loop of the Na+/Glucose Cotransporter Assessed by Intrinsic Tryptophan Fluorescence
138. Short‐term PHLORIZIN treatment attenuates adipose tissue inflammation without alerting obesity in high‐fat diet fed mice
139. Quantitative proteomics study on the protective mechanism of PHLORIZIN on hepatic damage in diabetic db/db mice
140. Effects of PHLORIZIN on net chloride movements across the valinomycin-treated erythrocyte membrane
141. PHLORIZIN exerts potent effects against aging induced by d-galactose in mice and PC12 cells
142. Insulin but not PHLORIZIN treatment induces a transient increase in GLUT2 gene expression in the kidney of diabetic rats
143. Lactase-PHLORIZIN hydrolase and sucrase-isomaltase genes are expressed differently along the villus-crypt axis of rat jejunum
144. Radiation inactivation studies of the renal brush-border membrane PHLORIZIN-binding protein.
145. Biosynthesis of intestinal microvillar proteins. Dimerization of aminopeptidase N and lactase-PHLORIZIN hydrolase
146. Expression of lactase-PHLORIZIN hydrolase in sheep is regulated at the RNA level
147. Pharmacological research on natural substances in Latvia: Focus on lunasin, betulin, polyprenol and PHLORIZIN
148. A method for measuring apical glucose transporter site density in intact intestinal mucosa by means of PHLORIZIN binding
149. Interaction of PHLORIZIN and sodium with the renal brush-border membrane D-glucose transporter: stoichiometry and order of binding
150. The T‐13910C polymorphism in the lactase PHLORIZIN hydrolase gene is associated with differences in serum calcium levels and calcium intake
151. Rat lactase-PHLORIZIN hydrolase/human growth hormone transgene is expressed on small intestinal villi in transgenic mice
152. Pharmacokinetic and pharmacodynamic modeling of the effect of an sodium-glucose cotransporter inhibitor, PHLORIZIN, on renal glucose transport in rats
153. PHLORIZIN, an active ingredient of Eleutherococcus senticosus, increases proliferative potential of keratinocytes with inhibition of MiR135b and increased …
154. Physical interaction between GATA-5 and hepatocyte nuclear factor-1α results in synergistic activation of the human lactase-PHLORIZIN hydrolase promoter
155. Studies on the inhibition of immune hemolysis by PHLORIZIN
156. Sodium-glucose cotransporters display sodium-and PHLORIZIN-dependent water permeability
157. Structure, biosynthesis and regulation of lactase-PHLORIZIN hydrolase
158. Dual SGLT1/SGLT2 inhibitor PHLORIZIN ameliorates non-alcoholic fatty liver disease and hepatic glucose production in type 2 diabetic mice
159. Comparison of improving effects for diabetic erectile dysfunction according to the anti-glycemic agents: PHLORIZIN and insulin
160. Investigation of three doses of oral insulin-like growth factor-I on jejunal lactase PHLORIZIN hydrolase activity and gene expression and enterocyte proliferation …
161. PHLORIZIN released by apple root debris is related to apple replant disease
162. Asymmetric inhibition by PHLORIZIN of sulfate movements across the red blood cell membrane
163. Synthesis of PHLORIZIN derivatives and their inhibitory effect on the renal sodium/D-glucose cotransport system
164. Similarity in effects of Na+ gradients and membrane potentials on D-glucose transport by, and PHLORIZIN binding to, vesicles derived from brush borders of rabbit …
165. PHLORIZIN induces lipolysis and alters meal patterns in both early-and late-lactation dairy cows
166. Effects of PHLORIZIN on membrane cation-dependent adenosine triphosphatase and p-nitrophenyl phosphatase activities
167. Adrenergic mechanisms in the metabolic adaptation to fasting and feeding: effects of PHLORIZIN on diet-induced changes in sympathoadrenal activity in the rat
168. Identification of a region critically involved in the interaction of PHLORIZIN with the rabbit sodium-D-glucose cotransporter SGLT1
169. Some new synthetic flavonoid glycosides related in structure to PHLORIZIN
170. Glycosylation of lactase-PHLORIZIN hydrolase in rat small intestine during development
171. Lactase-PHLORIZIN hydrolase and aminopeptidase N are differentially regulated in the small intestine of the pig
172. PHLORIZIN inhibits hexose transport across the plasmalemma of Riccia fluitans
173. Transport, function, and sorting of lactase-PHLORIZIN hydrolase in Madin-Darby canine kidney cells.
174. Modular metabolic engineering for production of phloretic acid, phloretin and PHLORIZIN in Escherichia coli
175. Lactase-PHLORIZIN hydrolase complex from monkey small intestine: purification, properties and evidence for two catalytic sites
176. Hierarchy of sorting signals in chimeras of intestinal lactase-PHLORIZIN hydrolase and the influenza virus hemagglutinin
177. Partial purification of the sugar carrier of intestinal brush border membranes. Enrichment of the PHLORIZIN-binding component by selective extractions
178. Targeting of sodium–glucose cotransporters with PHLORIZIN inhibits polycystic kidney disease progression in Han: SPRD rats
179. PHLORIZIN-induced normoglycemia partially restores glucoregulation in diabetic dogs
180. The HOXC11 homeodomain protein interacts with the lactase-PHLORIZIN hydrolase promoter and stimulates HNF1α-dependent transcription
181. Follicular phase gonadotropin secretion in cyclic postpartum beef cows with PHLORIZIN-induced hypoglycemia
182. Partial purification of hog kidney sodium-D-glucose cotransport system by affinity chromatography on a PHLORIZIN polymer
183. PHLORIZIN administration ameliorates cognitive deficits by reducing oxidative stress, tau hyper‐phosphorylation, and neuroinflammation in a rat model of Alzheimer’s …
184. Crystal structure of PHLORIZIN and the iodothyronine deiodinase inhibitory activity of phloretin analogues
185. Recognition of PHLORIZIN by the carriers of sucrose and hexose in broad bean leaves
186. Oral IGF-I alters the posttranslational processing but not the activity of lactase-PHLORIZIN hydrolase in formula-fed neonatal pigs
187. β-Glucosidase (PHLORIZIN hydrolase) activity of the lactase fraction isolated from the small intestinal mucosa of infant rats, and the relationship between β-glucosidases …
188. Dimerization of lactase-PHLORIZIN hydrolase occurs in the endoplasmic reticulum, involves the putative membrane spanning domain and is required for an efficient …
189. Influence of glucose on the transmembrane action potential of papillary muscle: effects of concentration, PHLORIZIN and insulin, nonmetabolizable sugars, and …
190. A second enzyme defect in acquired lactase deficiency: lack of small‐intestinal PHLORIZIN‐hydrolase
191. Asymmetric inhibition by PHLORIZIN of halide movements across the red blood cell membrane
192. Apple PHLORIZIN supplementation attenuates oxidative stress in hamsters fed a high‐fat diet
193. High‐affinity PHLORIZIN binding to brush border membranes from small intestine: Identity with (a part of) the glucose transport system, dependence on the Na+‐gradient …
194. Normalization of glucose entry under the high glucose condition by PHLORIZIN attenuates the high glucose-induced morphological and functional changes of …
195. Isolation ofn-ethylmaleimide-labelled PHLORIZIN-sensitived-glucose binding protein of brush border membrane from rat kidney cortex
196. Distribution of sulfhydryl groups in intestinal brush border membranes. Localization of side-chains essential for glucose transport and PHLORIZIN binding.
197. Enzymatic hydrolysis of pyridoxine-5′-β-d-glucoside is catalyzed by intestinal lactase-PHLORIZIN hydrolase
198. Sequence of the precursor of intestinal lactase-PHLORIZIN hydrolase from fetal rat
199. Mitigation effects of PHLORIZIN immersion on acrylamide formation in fried potato strips
200. Maturation of Human Intestinal Lactase‐PHLORIZIN Hydrolase: Generation of the Brush Border form of the Enzyme Involves at Least Two Proteolytic Cleavage Steps
201. The Action of PHLORIZIN on Photosynthesis and Light-stimulated Ion Transport in Hydrodictyon africanum
202. Apple leaves and their major secondary metabolite PHLORIZIN exhibit distinct neuroprotective activities: Evidence from in vivo and in silico studies
203. Linear relationship of PHLORIZIN‐binding capacity and hexose uptake during differentiation in a clone of LLC‐PK1 cells
204. PHLORIZIN attenuates visceral hypersensitivity and colonic hyperpermeability in a rat model of irritable bowel syndrome
205. Transcriptional regulation of the lactase-PHLORIZIN hydrolase promoter by PDX-1
206. APPLICATIONS OF PHLORIZIN AND RECENT ADVANCES OF ITS SEPARATION AND PURIFICATION [J]
207. Insulin resistance in rats with non-insulin-dependent diabetes induced by neonatal (5 days) streptozotocin: evidence for reversal following PHLORIZIN treatment
208. Ultrastructure of isolated kidney mitochondria treated with PHLORIZIN and ATP
209. PHLORIZIN from sweet tea inhibits the progress of esophageal cancer by antagonizing the JAK2/STAT3 signaling pathway
210. PHLORIZIN binding to isolated enterocytes: membrane potential and sodium dependence
211. The Pancreatic β-Cell Recognition of Insulin Secretagogues: V. Binding and Stimulatory Action of PHLORIZIN
212. Effects of PHLORIZIN on glucose, water and sodium handling by the rat kidney.
213. Protein domains implicated in intracellular transport and sorting of lactase-PHLORIZIN hydrolase
214. PCR-RFLP genotyping assay for a lactase persistence polymorphism upstream of the lactase-PHLORIZIN hydrolase gene
215. Structural state of the Na+/d-glucose cotransporter in calf kidney brush-border membranes Target size analysis of Na+-dependent PHLORIZIN binding and Na+ …
216. Effect of PHLORIZIN on metabolic abnormalities in Spontaneously Diabetic Torii (SDT) rats
217. Two substrate sites in the renal Na+-d-glucose cotransporter studied by model analysis of PHLORIZIN binding and-d-glucose transport measurements
218. Studies on the Metabolism of Adipose Tissue. XVI. Inhibition by PHLORIZIN and Phloretin of the Insulin-stimulated Uptake of Glucose*
219. Inhibition of absorption of d-xylose by PHLORIZIN in the anesthetized rat
220. An enhancer activates the pig lactase PHLORIZIN hydrolase promoter in intestinal cells
221. The pro sequence of lactase-PHLORIZIN hydrolase is required for the enzyme to reach the plasma membrane: an intramolecular chaperone?
222. Lactase PHLORIZIN hydrolase synthesis is decreased in protein-malnourished pigs
223. Hydrogen ion-coupled transport of D-glucose by PHLORIZIN-sensitive sugar carrier in intestinal brush-border membranes
224. PHLORIZIN prevents electrically-induced ventricular tachyarrhythmia during ischemia in langendorff-perfused guinea-pig hearts
225. Novel interaction at the Cdx-2 binding sites of the lactase–PHLORIZIN hydrolase promoter
226. … under controlled electroosmotic flow and micellar electrokinetic chromatography for on-line concentration and determination of trace PHLORIZIN and quercitrin in urine …
227. The effect of PHLORIZIN on amino acid transport in rat-kidney-cortex slices
228. Two intestinal specific nuclear factors binding to the lactase‐PHLORIZIN hydrolase and sucrase‐isomaltase promoters are functionally related oligomeric molecules
229. Solid-phase synthesis of β-mono-substituted ketones and an application to the synthesis of a library of PHLORIZIN derivatives
230. Routing and processing of lactase-PHLORIZIN hydrolase in transfected Caco-2 cells
231. ALKALINE PHOSPHATASE ACTIVITY OF THE PROXIMAL CONVOLUTED TUBULES AND THE MECHANISM OF PHLORIZIN GLYCURESIS
232. Simultaneous separation and purification of chlorogenic acid, epicatechin, hyperoside and PHLORIZIN from thinned young Qinguan apples by successive use of …
233. Metabolomics insights of the immunomodulatory activities of PHLORIZIN and phloretin on human THP-1 macrophages
234. PHLORIZIN inhibition of the insulin expansion of the galactose space in the eviscerate rat
235. PHLORIZIN treatment prevents the decrease in plasma insulin levels but not the progressive histopathological changes in the pancreatic islets during aging of Zucker …
236. Proteolytic processing of human lactase-PHLORIZIN hydrolase is a two-step event: identification of the cleavage sites
237. Effects of PHLORIZIN and p-chloromercuribenzenesulfonic acid on sucrose and proline accumulation in detached tomato leaves submitted to NaCl and osmotic stresses
238. 1 kb of the lactase‐PHLORIZIN hydrolase promoter directs post‐weaning decline and small intestinal‐specific expression in transgenic mice
239. Treatment of streptozotocin-induced diabetic rats with vanadate and PHLORIZIN prevents the over-expression of the liver insulin receptor gene
240. Circular dichroism spectra of the inclusion complexes of PHLORIZIN in cyclodextrins
241. Effects of PHLORIZIN on glucose transport into blood and lymph
242. Effects of insulin on monosaccharide transport and incorporation of amino acids into protein in diaphragm differentiated with PHLORIZIN
243. Effect of glucose, PHLORIZIN, and parathyroid extract on renal phosphate transport in chickens
244. PHLORIZIN ameliorates obesity-associated endotoxemia and insulin resistance in high-fat diet-fed mice by targeting the gut microbiota and intestinal barrier integrity
245. The effect of PHLORIZIN on the multiplication of measles virus
246. Studies on the arrangement of a glucose sensitive PHLORIZIN binding site in the microvilli of isolated rat kidney brushborder
247. PHLORIZIN and renal phosphate secretion in the spiny dogfish Squalus acanthias
248. Developmental changes in lactase-PHLORIZIN hydrolase precursor isoforms in the rat.
249. The inhibition by PHLORIZIN of kidney microsomal inorganic pyrophosphate-glucose phosphotransferase and glucose 6-phosphatase
250. In vivo sucrase-isomaltase and lactase-PHLORIZIN hydrolase turnover in the fed adult rat
251. Maturation of human lactase‐PHLORIZIN hydrolase Proteolytic cleavage of precursor occurs after passage through the Golgi complex
252. Quantitation of PHLORIZIN and phloretin using an ultra high performance liquid chromatography–electrospray ionization tandem mass spectrometric method
253. Transepithelial transport in cell culture: Stoichiometry of Na/PHLORIZIN binding and Na/D-glucose cotransport. A two-step, two-sodium model of binding and …
254. Further studies of glycosylation and intracellular transport of lactase–PHLORIZIN hydrolase in rat small intestine
255. PHLORIZIN: its effect on glucose-induced insulin secretion and protection against the alloxan effect in isolated islets
256. Hepatocyte nuclear factor-1α is required for expression but dispensable for histone acetylation of the lactase-PHLORIZIN hydrolase gene in vivo
257. Competitive inhibition of SGLT2 by tofogliflozin or PHLORIZIN induces urinary glucose excretion through extending splay in cynomolgus monkeys
258. A hydrolase-related transport system is not required to explain the intestinal uptake of glucose liberated from PHLORIZIN
259. Abnormal B-cell function in rats with non-insulin-dependent diabetes induced by neonatal streptozotocin: effect of in vivo insulin, PHLORIZIN, or vanadate treatments.
260. Studies on transmural potentials in vitro in relation to intestinal absorption: IV. PHLORIZIN-sugar interactions in rat gut
261. Interrelations during renal tubular reabsorption in the dog among several anions showing a sensitivity to glucose and PHLORIZIN
262. Inhibition by PHLORIZIN of insulin-and protease-stimulated glucose utilization in isolated adipose cells
263. PHLORIZIN-induced glycosuria does not prevent gentamicin nephrotoxicity in rats
264. Derivatives of Plant Beta-GIucans Are Hydrolyzed by Intestinal Lactase-PHLORIZIN Hydrolase of Mammals
265. Processing of human pro-lactase-PHLORIZIN hydrolase at reduced temperatures: cleavage is preceded by complex glycosylation
266. Contribution of hyperglycemia on diabetic complications in obese type 2 diabetic SDT fatty rats: effects of SGLT inhibitor PHLORIZIN
267. Verification of the lactase site of rat lactase-PHLORIZIN hydrolase by site-directed mutagenesis
268. Insulin, anaerobiosis, and PHLORIZIN in entry of d-galactose into skeletal muscle
269. Mechanism of maturational decline of rat intestinal lactase-PHLORIZIN hydrolase
270. A comparative study of intestinal PHLORIZIN hydrolase in various animal species
271. Folding of human intestinal lactase-PHLORIZIN hydrolase
272. Action of PHLORIZIN on Acid Phosphatase Activity and on Glucose Phosphorylation of Kidney Cortex Extracts.
273. Hypoglycemic and hypolipidemic activities of PHLORIZIN from Lithocarpus polystachyus Rehd in diabetes rats
274. Genetic regulation of enterocyte function: a quantitative in situ hybridisation study of lactase-PHLORIZIN hydrolase and Na+-glucose cotransporter mRNAs in rabbit small …
275. Apple PHLORIZIN reduce plasma cholesterol by down-regulating hepatic HMG-CoA reductase and enhancing the excretion of fecal sterols
276. Processing and transport of human small intestinal lactase-PHLORIZIN hydrolase (LPH): Role of N-linked oligosaccharide modification
277. Effects of PHLORIZIN and ouabain on the polarity of mouse 4-cell/16-cell stage blastomere heterokaryons
278. Effects of glucose, 2-deoxyglucose, PHLORIZIN, and insulin on food intake of lean and fatty rats
279. Action of PHLORIZIN on luminal and antiluminal membranes of proximal cells of kidney
280. Studies on the Inhibitors of the Sodium-Potassium Activated Adenosinetriphos phatase. I. Effect of PHLORIZIN and Related Natural Products
281. The effect of PHLORIZIN on the metabolism of cytolysing sea-urchin eggs
282. Isolation and partial purification of a Na+-dependent PHLORIZIN receptor from dog kidney proximal tubule.
283. Demonstration of glucose inhibitable PHLORIZIN binding to renal brushborder proteins separated by gel electrophoresis
284. A two sodium ion/D-glucose symport mechanism: membrane potential effects on PHLORIZIN binding
285. Small-intestinal Na+/D-glucose cotransport. Inactivation of sugar transport and PHLORIZIN binding by thiol-group and amino-group reagents
286. N-ethylmaleimide labeling of a PHLORIZIN-sensitive D-glucose binding site of brush border membrane from the rat kidney
287. Region-specific expression of multiple lactase-PHLORIZIN hydrolase genes in intestine of rabbit
288. Regulatory regions in the rat lactase-PHLORIZIN hydrolase gene that control cell-specific expression
289. Specific photoaffinity inactivation of the D-glucose transporter in small intestinal brush border membrane using new PHLORIZIN analogs
290. The kinetic advantage for transport into hamster intestine of glucose generated from PHLORIZIN by brush border β-glucosidase
291. Isolation and characterization of the proximal and distal forms of lactase-PHLORIZIN hydrolase from the small intestine of the suckling rat
292. Studies on the spatial relationship between intestinal disaccharidases and the PHLORIZIN-sensitive transport of glucose
293. Systemic PHLORIZIN prevents gold thioglucose necrosis in the ventromedial hypothalamus
294. Genotyping of the Lactase-PHLORIZIN Hydrolase C/T-13910 Polymorphism by Means of a New Rapid Denaturing High-Performance Liquid Chromatography-Based …
295. Effect of PHLORIZIN on the in Vitro Release of Histamine from Lung Tissue1
296. Biotransformation of PHLORIZIN by Eurotium cristatum to Increase the Antioxidant and Antibacterial Activity of Docynia indica Leaves
297. Proteolytic processing of human intestinal lactase-PHLORIZIN hydrolase precursor is not a prerequisite for correct sorting in Madin Darby canine kidney (MDCK) cells
298. PHLORIZIN treatment attenuates obesity and related disorders through improving BAT thermogenesis
299. Synthesis of [3H] PHLORIZIN and its binding behavior to renal brush-border membranes
300. Light activation of pyruvate, Pi dikinase and NADP-malate dehydrogenase in mesophyll protoplasts of maize: effect of DCMU, antimycin A, CCCP, and PHLORIZIN
301. Effect of PHLORIZIN on exchange and non-exchange transport of sugars in human erythrocytes
302. The effects of PHLORIZIN stress on the protective enzyme and metabolic regulation substances in the root of M. micromalus
303. PHLORIZIN or vanadate treatment reverses impaired expression of albumin and hepatocyte nuclear factor 1 in diabetic rats
304. Hymenolepis diminuta: properties of PHLORIZIN inhibition of glucose transport
305. The pro-region of human intestinal lactase-PHLORIZIN hydrolase is enzymatically inactive towards lactose.
306. Immunocytochemical heterogeneity of lactase-PHLORIZIN hydrolase in adult lactase deficiency
307. The apical sorting of lactase-PHLORIZIN hydrolase implicates sorting sequences found in the mature domain.
308. Quantitative analysis of lactase‐PHLORIZIN hydrolase expression in the absorptive enterocytes of newborn rat small intestine
309. On the absence of PHLORIZIN hydrolase in renal brush border membranes
310. Oligomeric structure of the sodium-dependent PHLORIZIN binding protein from kidney brush-border membranes
311. Effects of glucagon, glycerol, and insulin on PHLORIZIN-induced ketosis in fasted, non-pregnant ewes.
312. The effects of PHLORIZIN, phloretin and ouabain on the reabsorption of glucose by the Malpighian tubules of Locusta migratoria migratorioides
313. Is PHLORIZIN or its aglycon the inhibitor of intestinal glucose transport? A study in normal and lactase deficient man
314. The affinity of PHLORIZIN-like compounds for a β-glucosidase in intestinal brush borders: comparison with the glucose transport system
315. Study on Inhibitory Activity of PHLORIZIN against Tyrosinase [J]
316. Human lactase–PHLORIZIN hydrolase: evidence of dimerization in the endoplasmic reticulum
317. Interaction of PHLORIZIN, a potent inhibitor of the Na+/D‐glucose cotransporter, with the NADPH‐binding site of mammalian catalases
318. Different PHLORIZIN binding properties to porcine mucosa of the jejunum and ileum in relation to SGLT1 activity
319. Immunomodulatory activities of PHLORIZIN metabolites in lipopolysaccharide-stimulated RAW264. 7 cells
320. The lactase PHLORIZIN hydrolase (LCT) gene maps to pig chromosome 15q13
321. Suckling rat colon synthesizes and processes active lactase-PHLORIZIN hydrolase immunologically identical to that from jejunum
322. The Crystal and Molecular Structure of PHLORIZIN Dihydrate
323. Induction of ependymal, glial, and neuronal transactivation by intraventricular administration of the SGLT1 Na+-D-glucose cotransporter inhibitor PHLORIZIN
324. Binding of PHLORIZIN to the C-terminal loop 13 of the Na+/glucose cotransporter does not depend on the [560–608] disulfide bond
325. High-affinity PHLORIZIN binding in Mytilus gill
326. Competitive kinetics in the inhibition of sugar intestinal transport by PHLORIZIN, in vivo.
327. Furin, PC1/3, and/or PC6A Process Rabbit, but Not Human, Pro-lactase-PHLORIZIN Hydrolase to the 180-kDa Intermediate (∗)
328. Effects of PHLORIZIN and heparin on ketonemia in fasted, nonpregnant ewes.
329. Pharmacological investigations on efficacy of PHLORIZIN a sodium-glucose co-transporter (SGLT) inhibitor in mouse model of intracerebroventricular streptozotocin …
330. A possible role of a nuclear factor NF-LPH1 in the regional expression of lactase-PHLORIZIN hydrolase along the small intestine
331. Molecular interaction of PHLORIZIN and cyclodextrins
332. Paradoxical effect of PHLORIZIN on glucose uptake and intracellular accumulation of amino-acids in rat kidney slices in vitro
333. Restoration of the Attenuated Neuroprotective Effect of Ischemic Postconditioning in Diabetic Mice by SGLT Inhibitor PHLORIZIN
334. Human lactase‐PHLORIZIN hydrolase expressed in COS‐1 cells is proteolytically processed by the lysosomal pathway
335. Heterogeneity of intestinal lactase activity in children: relationship to lactase-PHLORIZIN hydrolase messenger RNA abundance
336. Study on the dynamic changes of PHLORIZIN and phloretin in leave and branches of apple tree.
337. PHLORIZIN stimulation of p-aminohippurate uptake in rat kidney cortex slices
338. Enzymatic Production of 3-OH PHLORIZIN, a Possible Bioactive Polyphenol from Apples, by Bacillus megaterium CYP102A1 via Regioselective Hydroxylation
339. EFFECTS OF 2-DEOXYGLtJCOSE, PHLORIZIN, INSULIN AND OUABAIN ON GLUCOSE-DEPENDENT ANAPHYLACTIC HISTAMINE RELEASE FROM GUINEA-PIG …
340. Preparative isolation and purification of PHLORIZIN from apple tree bark by high-speed counter-current chromatography.
341. Structural determinants for transport of lactase PHLORIZIN-hydrolase in the early secretory pathway as a multi-domain membrane glycoprotein
342. Antecedent chronic hyperglycaemia blocks PHLORIZIN-induced insulin resistance in the dog
343. Hexosamine metabolism II. effect of insulin and PHLORIZIN on the absorption and metabolism, in vivo, of d-glucosamine and N-acetyl-d-glucosamine in the rat
344. PHLORIZIN receptors in isolated kidney brush border membranes Differential enzymatic modification of high-affinity receptors and unspecific binding sites
345. PHLORIZIN glycosuria in the diagnosis of pregnancy
346. Effect of PHLORIZIN on galactose influx in rabbit intestine
347. … competitive inhibition and activation in Michaelian enzyme and transport systems. Application to the competitive inhibition of glucose transport in brain by PHLORIZIN …
348. In Vivo Absorption of Phenytoin from Rat Small Intestine and its Inhibition by PHLORIZIN
349. Thyroid and glucocorticoid hormones induce expression of lactase-PHLORIZIN hydrolase gene in CDX-2/HNF-1α co-transfected IEC-6 cells
350. Fluorescence probe studies on the interaction of PHLORIZIN with rabbit intestinal brush border membranes
351. The interaction of phenformin and PHLORIZIN with brush border membrane vesicles, phospholipid liposomes, and phospholipid liposomes containing brush border …
352. Identification and characterization of PHLORIZIN transporter from Arabidopsis thaliana and its application for PHLORIZIN production in Saccharomyces cerevisiae
353. Deglycosylation of individual flavonoids and flavonoid containing plant extracts by purified human intestinal lactase-PHLORIZIN hydrolase (LPH)
354. Translocation of organic compounds in sunflower III. Effect of oligomycin, ouabain and PHLORIZIN on translocation of sugars
355. Effects of epinephrine, hydrocortisone, and thyroxine on PHLORIZIN-induced ketosis in fasted, nonpregnant ewes.
356. D‐glucose transporter on mussel mantle cell membranes: Effect of sodium and PHLORIZIN
357. Rabbit intestinal glucose-6-phosphate phosphohydrolase and inorganic pyrophosphate glucose phosphotransferase: inhibition by PHLORIZIN
358. Lactase and PHLORIZIN hydrolase from rabbit small intestine
359. A PHLORIZIN Polymer as Affinity Gel for Sugar‐Binding Proteins
360. Disposition of the car☐ y-terminus tail of rabbit lactase-PHLORIZIN hydrolase elucidated by phosphorylation with protein kinase A in vitro and in tissue culture
361. Lactase-PHLORIZIN hydrolase complex from monkey small intestine: Stimulation of pillorizin hydrolase activity by organic acids
362. Purification of a putative Na+ /D‐glucose cotransporter from pig kidney brush border membranes on a PHLORIZIN affinity column
363. Study on interaction between PHLORIZIN and human serum albumin by spectroscopic methods
364. In vitro hepatic gluconeogenesis during experimental ketosis produced in steers by 1, 3-butanediol and PHLORIZIN
365. Effect of PHLORIZIN treatment on postharvest gray mold of apples.
366. Protein metabolism in PHLORIZIN diabetes
367. Changes in glucose uptake by and PHLORIZIN binding to brush-border membrane vesicles of small intestine from streptozotocin-induced diabetic rats
368. … acid sequence and mRNA analysis of cytosolic pyridoxine-beta-D-glucoside hydrolase from porcine intestinal mucosa: proposed derivation from the lactase-PHLORIZIN …
369. D-galactose uptake by snail intestine: competitive inhibition by PHLORIZIN and sodium dependence.
370. Effect of PHLORIZIN on the changes of membrane potential, water, Na and K transport induced by cevadine in frog muscle.
371. … BETWEEN DNA METHYLATION OF THE CHALCONE ISOMERASE GENE IN LITHOCARPUS POLYSTACHYUS REHD.(FAGACEAE) AND PHLORIZIN …
372. Isoosmotic Transport of Fluid Across the Hamster Small Intestine in the Presence of PHLORIZIN-Induced Inhibition of Sugar Transport
373. The inhibition of glucose-6-phosphatase by PHLORIZIN and structurally related compounds
374. Administration of 3, 5, 3’‐triiodothyronine induces a rapid increase in enterocyte lactase‐PHLORIZIN hydrolase activity of young pigs on a low energy intake
375. Investigating the stimulatory mechanisms of PHLORIZIN, phloretin and chlorogenic acid polyphenols on Akkermansia muciniphila in vitro
376. PHLORIZIN binding to bilayer vesicles of phospholipids and phospholipid-cholesterol
377. Some effects of PHLORIZIN and phloretin on renal amino acid reabsorption in the dog
378. Substrate oxidation by isolated ovine enterocytes is increased by PHLORIZIN-induced glucosuria
379. PHLORIZIN and sorbitol in Vitis labrusca grape juices
380. Study on Extraction Technology of PHLORIZIN in Litchi Pericarp [J]
381. The PHLORIZIN effect on the transport of sugars at the antiluminal face of teased flounder tubules.
382. PHLORIZIN-receptor interactions in fat cell plasma membranes
383. Studies on the mechanism of action of PHLORIZIN
384. [43] Photoafflnity-labeling analogs of PHLORIZIN and phloretin: Synthesis and effects on cell membranes
385. Effect of PHLORIZIN on hepatic bile production before and during glucose infusion
386. … ) phenoxy]-d-glucopyranoside and [(4′-benzoyl) phenoxy]-d-glucopyranoside for the identification of sugar-binding and PHLORIZIN-binding sites in the sodium/d …
387. Molecular cloning of a novel cDNA from Mus muscular BALB/c mice encoding glycosyl hydrolase family 1: a homolog of human lactase-PHLORIZIN hydrolase.
388. Structure, Function, and Regulation of Intestinal Lactase-PHLORIZIN Hydrolase and Sucrase-Isomaltase in Health and Disease
389. A comparison of PHLORIZIN and phloretin adsorption by the tapeworm Hymenolepis diminuta.
390. Analysis of the proteolytic processing of lactase-PHLORIZIN hydrolase
391. Effect of PHLORIZIN on the action potential and voltage-dependent ionic conductances in frog skeletal muscle.
392. Persistence of disturbed adipocyte metabolism in sterptozocin-induced diabetic rats despite near-euglycemia with PHLORIZIN
393. The combined action of insulin and PHLORIZIN on transport and metabolism of sugars and nucleotide turnover in the isolated rat diaphragm
394. Reduction in the Amplitude of Shortening and Ca2+ Transient by PHLORIZIN and Quercetin-3-O-Glucoside in Ventricular Myocytes From Streptozotocin-Induced …
395. Chloride-dependence of the actions of PHLORIZIN on frog skeletal muscle membrane.
396. Amelioration of PHLORIZIN-induced autotoxicity in Malus hupehensis by rhizobium
397. Effect of PHLORIZIN on glucose transport in the inner ear
398. The mechanism of coupling between glucose transport and electrical potential in the proximal tubule: A study of potential-dependent PHLORIZIN binding to isolated renal …
399. Binding of [3H] PHLORIZIN to rat kidney plasma membranes
400. PHLORIZIN derivatives as photoaffinity labels of the Na+, D-glucose transporter in brush border membranes
401. The action of inhibitors of sugar transport PHLORIZIN, phloretin and cytochalasin B in model systems
402. Inhibition of sodium for sodium exchange by PHLORIZIN in frog sartorius muscle.
403. Defective Intracellular Processing of Lactase‐PHLORIZIN Hydrolase Protein in Rats Prenatally Exposed to Ethanol
404. … Reactive Ezrin Surface Area Increases in Glomerular Podocytes of STZ Diabetic Rats Precede Their Detachment, Is Prevented by PHLORIZIN But Not by Insulin
405. PHLORIZIN vs
406. The role of transporter ectodomains in drug recognition and binding: PHLORIZIN and the sodium–glucose cotransporter
407. Characterization of expression in mice of a transgene containing 3.3 kb of the human lactase-PHLORIZIN hydrolase (LPH) 5′ flanking sequence
408. Variations in the acid-base equilibrium in hypoglycemic PHLORIZIN diabetes.
409. Effects of PHLORIZIN and phloretin on passive and dynamic electrical properties in muscle membrane.
410. LXI.—On PHLORIZIN
411. The Effects of PHLORIZIN, 2, 4-dinitrophenol, and Oxygen Deprivation on the Intestinal Transport of D-glucose
412. Human lactase-PHLORIZIN hydrolase is not processed by furin, PC1/PC3, PC2, PACE4 and PC5/PC6A of the family of subtilisin-like proprotein processing proteases
413. Immunoelectron Microscopic Localization of Lactase-PHLORIZIN Hydrolase in Rat Small Intestine
414. Do co-translated product (s) of lactase-PHLORIZIN hydrolase accumulate in the rat intestine?
415. Characterization of natural and artificial mutants of human intestinal lactase PHLORIZIN hydrolase
416. Distinguishing between hydrophilic and hydrophobic subunits of human lactase-PHLORIZIN hydrolase by gel filtration
417. I. INHIBITION OF PHOTOPHOSPHORYLATION BY PHLORIZIN
418. In-Vitro Antioxidant Activity and Free Radical Scavenging Potential of PHLORIZIN Derived Sodium Glucose Cotransporter 2 Inhibitor
419. THE INTRAVENOUS PHLORIZIN TEST
420. Effects of PHLORIZIN on Renal Function
421. THE EFFECT OF PHLORIZIN UPON GLOMERULAR FILTRATION
422. Photo-activated inhibition of sulfate equilibrium exchange in human erythrocyte ghosts by A 4-azido-2-nitrobenzoate derivative of PHLORIZIN
423. Interaction and Antioxidant Activities of PHLORIZIN and Bovine Hemoglobin in Three Different Solvents
424. Comparition of PHLORIZIN recovery with different solid phase extraction cartridges
425. Isolation, Identification and Degrading Properties of PHLORIZIN-Degrading Fungi
426. A STUDY OF SOME EFFECTS OF PHLORIZIN ON THE METABOLISM OF KIDNEY TISSUE IN VITRO
427. Effects of PHLORIZIN on aorta of diabetes db/db mice
428. Lack of effect of charge of PHLORIZIN and phloretin on mutarotase action
429. Purification of PHLORIZIN from Malus domestica Borkh. leaves by solid-phase extraction and semi-preparative high performance liquid chromatography.
430. Therapeutic effects of PHLORIZIN on the early stage of diabetic retinopathy in diabetic db/db mice
431. High affinity PHLORIZIN binding to the small intestinal Na exp+, D-glucose carrier
432. The effects of PHLORIZIN on serum lipid profile and oxidative stress parameters in sheep.
433. Effect of PHLORIZIN on sugar uptake by broadbean leaf discs.[Vica faba L]
434. Expression and characterization of Lactase PHLORIZIN Hydrolase region III.
435. Interaction of PHLORIZIN and phloretin with glucose transport system of the pigeon intestine
436. Component analysis of Valsa mali var. mali fermentation liquid degrading PHLORIZIN
437. Component analysis of Valsa mali var. mali fermentation liquid degrading PHLORIZIN.
438. Bioconversion of PHLORIZIN to phloretin by a selected Penicillium purpurescens strain QL-9204
439. Enhancement of Gibberellic Acid-stimulated Hypocotyl Elongation of Lettuce (Lactuca sativa L. cv. Grand Rapids) by PHLORIZIN and Light
440. Lactase-PHLORIZIN hydrolase: primary structure determination via cDNA cloning of the rabbit enzyme and developmental regulation in rabbit and human
441. Hyperglycæmia following absorption of glucose in dogs subjected to different treatments: normal diet, high sugar diet, starvation, injection of PHLORIZIN.
442. The Influence on the Yield of PHLORIZIN in Lithocarpus Polysachyus Rehd Fermented by Saussurea Bacteria
443. PHLORIZIN Significantly Increases Glucosuria in Normoglycemic Rats but not in Zucker Diabetic Fatty (ZDF) or Streptozotocin-Induced (STZ) Diabetic Rats
444. GLYCOSYLATION OF LACTASE-PHLORIZIN HYDROLASE (L-Ph) IN RAT SMALL INTESTINE DURING DEVELOPMENT
445. COORDINATE EXPRESSION OF LACTASE-PHLORIZIN HYDROLASE (L-PH) mRNA AND ENZYME LEVELS IN RAT INTESTINE DURING DEVELOPMENT
446. The biochemical and genetical analysis of lactase PHLORIZIN hydrolase: with specific reference to the lactase persistence/non-persistence polymorphism in …
447. P003: PHLORIZIN, an active ingredient of eleutherococcus senticosus, increases proliferative activity of keratinocytes with increased expression of type iv collagen and …
448. INTESTINAL ABSORPTION OF GLUCOSE HYDROLYZED FROM PHLORIZIN BY A BRUSH BORDER GLYCOSIDASE AND AN AFFINITY CHROMATOGRAPHY …
449. 49 SEQUENCE VARIABILITY AMONG THE PROMOTER REGION OF THE HUMAN LACTASE-PHLORIZIN HYDROLASE (LPH) GENE
450. Routing of normal and mutant brush-border sucrase-isomaltase and lactase-PHLORIZIN hydrolase
451. PRIMARY SEQUENCE OF CODING RECION OF LACTASE-PHLORIZIN HYDROLASE GENE IN CONGENITAL HUMAN LACTASE DEFICIENCY
452. Hepatocyte nuclear factor-1alpha is required for gene-expression, but dispensable for histone acetylation of the lactase-PHLORIZIN hydrolase gene
453. PHLORIZIN Treatment Of Zucker Diabetic Fatty (ZDF) Rats For One Week Decreased Blood Glucose And Triglycerides Without Significant Alterations of Urine Volume …
454. 1. 48 to 6. 28+ 1. 20 pmol/mm min (P & 0.01) when glucose was added to the perfusate. PHLORIZIN 10-5M in the lumen reduced the lumen
455. 48 RAT LACTASE-PHLORIZIN HYDROLASE HAS ONE MAIN ACTIVE SITE WITH B-GLUCOSIDASE AND B-GALACTOSIDASE ACTIVITY
456. … STUDIES WITH HYPOGLYCEMIC AND KETONEMIC SHEEP. I. EFFECTS OF GLUCAGON, GLYCEROL AND INSULIN ON PHLORIZIN-INDUCED KETOSIS IN …
457. EFFECTS OF 2-DEOXYGLtJCOSE, PHLORIZIN, INSULIN AND OUABAIN ON GLUCOSE-DEPENDENT ANAPHYLACTIC HISTAMINE RELEASE FROM GUINEA-PIG …
458. (18) Biodiversity of the Flavonoid PHLORIZIN in a Subset of the USDA Apple Germplasm Core Collection