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      HYPOCRETIN OREXIN
      December 22, 2021
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      DYNORPHIN
      December 22, 2021
      1. TRYPTOPHAN HYDROXYLASE –2 controls brain serotonin synthesis
      2. TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene variants associated with ADHD
      3. TRYPTOPHAN HYDROXYLASE –2 (TPH2 ) in disorders of cognitive control and emotion regulation: a perspective
      4. Loss-of-function mutation in TRYPTOPHAN HYDROXYLASE –2 identified in unipolar major depression
      5. Amygdala responsiveness is modulated by TRYPTOPHAN HYDROXYLASE –2 gene variation
      6. TRYPTOPHAN HYDROXYLASE –2 gene variation influences personality traits and disorders related to emotional dysregulation
      7. Brain-specific TRYPTOPHAN HYDROXYLASE 2 (TPH2 ): a functional Pro2 06Ser substitution and variation in the 5′-region are associated with bipolar affective disorder
      8. A regulatory variant of the human TRYPTOPHAN HYDROXYLASE –2 gene biases amygdala reactivity
      9. Functional domains of human TRYPTOPHAN HYDROXYLASE 2 (hTPH2 )
      10. Impaired executive control is associated with a variation in the promoter region of the TRYPTOPHAN HYDROXYLASE 2 gene
      11. Effect of TRYPTOPHAN HYDROXYLASE –2 gene variants on suicide risk in major depression
      12. TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) haplotypes predict levels of TPH2 mRNA expression in human pons
      13. Elevated expression of TRYPTOPHAN HYDROXYLASE –2 mRNA at the neuronal level in the dorsal and median raphe nuclei of depressed suicides
      14. TRYPTOPHAN HYDROXYLASE 2 gene is associated with major depression and antidepressant treatment response
      15. Up-regulation of TRYPTOPHAN HYDROXYLASE –2 mRNA in the rat brain by chronic fluoxetine treatment correlates with its antidepressant effect
      16. Deficient serotonin neurotransmission and depression-like serotonin biomarker alterations in TRYPTOPHAN HYDROXYLASE 2 (Tph2 ) loss-of-function mice
      17. Transmission disequilibrium of polymorphic variants in the TRYPTOPHAN HYDROXYLASE –2 gene in attention-deficit/hyperactivity disorder
      18. Genotype-dependent activity of TRYPTOPHAN HYDROXYLASE –2 determines the response to citalopram in a mouse model of depression
      19. Association of functional polymorphisms of the human TRYPTOPHAN HYDROXYLASE 2 gene with risk for bipolar disorder in Han Chinese
      20. In silico analysis of the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) protein variants related to psychiatric disorders
      21. Activation and stabilization of human TRYPTOPHAN HYDROXYLASE 2 by phosphorylation and 14-3-3 binding
      22. Haplotype-based linkage of TRYPTOPHAN HYDROXYLASE 2 to suicide attempt, major depression, and cerebrospinal fluid 5-hydroxyindoleacetic acid in 4 populations
      23. Additive effects of serotonin transporter and TRYPTOPHAN HYDROXYLASE –2 gene variation on emotional processing
      24. Advances in TRYPTOPHAN HYDROXYLASE ‐2 gene expression regulation: New insights into serotonin–stress interaction and clinical implications
      25. TRYPTOPHAN HYDROXYLASE –2 : an emerging therapeutic target for stress disorders
      26. TRYPTOPHAN HYDROXYLASE 1 knockout and TRYPTOPHAN HYDROXYLASE 2 polymorphism: effects on hypoxic pulmonary hypertension in mice
      27. A TRYPTOPHAN HYDROXYLASE 2 gene polymorphism is associated with panic disorder
      28. Estrogen receptor beta regulates the expression of TRYPTOPHAN–HYDROXYLASE 2 mRNA within serotonergic neurons of the rat dorsal raphe nuclei
      29. No human TRYPTOPHAN HYDROXYLASE –2 gene R441H mutation in a large cohort of psychiatric patients and control subjects
      30. Effect of TRYPTOPHAN HYDROXYLASE –2 gene variants on amygdalar and hippocampal volumes
      31. TRYPTOPHAN–HYDROXYLASE 2 haplotype association with borderline personality disorder and aggression in a sample of patients with personality disorders and healthy …
      32. Transmission disequilibrium of polymorphic variants in the TRYPTOPHAN HYDROXYLASE –2 gene in children and adolescents with obsessive–compulsive disorder
      33. 1, 2 5‐Dihydroxyvitamin D regulates expression of the TRYPTOPHAN HYDROXYLASE 2 and leptin genes: implication for behavioral influences of vitamin D
      34. Additive effects of serotonin transporter and TRYPTOPHAN HYDROXYLASE –2 gene variation on neural correlates of affective processing
      35. Estrogen selectively increases TRYPTOPHAN HYDROXYLASE –2 mRNA expression in distinct subregions of rat midbrain raphe nucleus: association between gene expression …
      36. Functional polymorphisms of the brain serotonin synthesizing enzyme TRYPTOPHAN HYDROXYLASE –2
      37. Characterization of a functional promoter polymorphism of the human TRYPTOPHAN HYDROXYLASE 2 gene in serotonergic raphe neurons
      38. Genetic architecture of the human TRYPTOPHAN HYDROXYLASE 2 Gene: existence of neural isoforms and relevance for major depression
      39. Daily rhythm of TRYPTOPHAN HYDROXYLASE –2 messenger ribonucleic acid within raphe neurons is induced by corticoid daily surge and modulated by enhanced locomotor …
      40. Common genetic variations in human brain-specific TRYPTOPHAN HYDROXYLASE –2 and response to antidepressant treatment
      41. Local gyrification index in patients with major depressive disorder and its association with TRYPTOPHAN HYDROXYLASE ‐2 (TPH2 ) polymorphism
      42. Polymorphism of the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene is associated with chimpanzee neuroticism
      43. Possible association between response inhibition and a variant in the brain-expressed TRYPTOPHAN HYDROXYLASE –2 gene
      44. Zebrafish tyrosine HYDROXYLASE 2 gene encodes TRYPTOPHAN HYDROXYLASE
      45. Association study of TRYPTOPHAN HYDROXYLASE –2 gene in schizophrenia and its clinical features in Chinese Han population
      46. Oxidative damage of TRYPTOPHAN HYDROXYLASE –2 mediated by peroxisomal superoxide anion radical in brains of mouse with depression
      47. Differential hormonal regulation of TRYPTOPHAN HYDROXYLASE –2 mRNA in the murine dorsal raphe nucleus
      48. Quantitative mapping of TRYPTOPHAN HYDROXYLASE ‐2 , 5‐HT1A, 5‐HT1B, and serotonin transporter expression across the anteroposterior axis of the rat dorsal and …
      49. Effect of pharmacological chaperones on brain tyrosine HYDROXYLASE and TRYPTOPHAN HYDROXYLASE 2
      50. Maternal high-fat diet stimulates proinflammatory pathway and increases the expression of TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) and brain-derived neurotrophic …
      51. Targeting TRYPTOPHAN HYDROXYLASE 2 in affective disorder
      52. The relationship of TRYPTOPHAN HYDROXYLASE –2 methylation to early-life stress and its impact on short-term antidepressant treatment response
      53. TRYPTOPHAN HYDROXYLASE 2 in seasonal affective disorder: underestimated perspectives?
      54. A functional variant of the TRYPTOPHAN HYDROXYLASE 2 gene impacts working memory: a genetic imaging study
      55. A regulatory domain in the N terminus of TRYPTOPHAN HYDROXYLASE 2 controls enzyme expression
      56. Role of the novel TRYPTOPHAN HYDROXYLASE –2 gene in Tourette syndrome
      57. A loss-of-function mutation in TRYPTOPHAN HYDROXYLASE 2 segregating with attention-deficit/hyperactivity disorder
      58. Effect of TRYPTOPHAN HYDROXYLASE –2 rs7305115 SNP on suicide attempts risk in major depression
      59. TRYPTOPHAN HYDROXYLASE 2 genotype determines brain serotonin synthesis but not tissue content in C57Bl/6 and BALB/c congenic mice
      60. Serotonin and early cognitive development: Variation in the TRYPTOPHAN HYDROXYLASE 2 gene is associated with visual attention in 7‐month‐old infants
      61. TRYPTOPHAN HYDROXYLASE 2 as a therapeutic target for psychiatric disorders: Focus on animal models
      62. TRYPTOPHAN HYDROXYLASE 2 gene expression and promoter polymorphisms in bipolar disorder and schizophrenia
      63. Glucocorticoid modulation of TRYPTOPHAN HYDROXYLASE –2 protein in raphe nuclei and 5-hydroxyTRYPTOPHAN concentrations in frontal cortex of C57/Bl6 mice
      64. Characterization of wild‐type and mutant forms of human TRYPTOPHAN HYDROXYLASE 2
      65. The novel brain-specific TRYPTOPHAN HYDROXYLASE –2 gene in panic disorder
      66. Serotonin synthesis rate and the TRYPTOPHAN HYDROXYLASE –2 : G-703T polymorphism in social anxiety disorder
      67. C1473G polymorphism in mouse tph2 gene is linked to TRYPTOPHAN HYDROXYLASE ‐2 activity in the brain, intermale aggression, and depressive‐like behavior in the …
      68. Investigation of the TRYPTOPHAN HYDROXYLASE 2 gene in bipolar I disorder in the Romanian population
      69. Association between TRYPTOPHAN HYDROXYLASE 2 gene polymorphism and completed suicide
      70. Variations in TRYPTOPHAN HYDROXYLASE 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression
      71. Effect of repeated treatment with fluoxetine on TRYPTOPHAN HYDROXYLASE –2 gene expression in the rat brainstem
      72. Polymorphisms in the neuronal isoform of TRYPTOPHAN HYDROXYLASE 2 are associated with bipolar disorder in French Canadian pedigrees
      73. Association study of TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms in panic disorder
      74. Association with TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms and autism spectrum disorders in Korean families
      75. TRYPTOPHAN HYDROXYLASE 2 gene is associated with major depressive disorder in a female Chinese population
      76. A functional alternative splicing mutation in human TRYPTOPHAN HYDROXYLASE –2
      77. Functional properties of missense variants of human TRYPTOPHAN HYDROXYLASE 2
      78. TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms and poststroke anxiety disorders
      79. Distribution of the C1473G polymorphism in TRYPTOPHAN HYDROXYLASE 2 gene in laboratory and wild mice
      80. Risk-taking behavior in a gambling task associated with variations in the TRYPTOPHAN HYDROXYLASE 2 gene: relevance to psychiatric disorders
      81. Generation of TRYPTOPHAN HYDROXYLASE 2 gene knockout pigs by CRISPR/Cas9-mediated gene targeting
      82. TRYPTOPHAN HYDROXYLASE 2 (TPH 2 ) in a neuronal cell line: modulation by cell differentiation and NRSF/rest activity
      83. TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene polymorphisms and psychiatric comorbidities in temporal lobe epilepsy
      84. Effect of metals and phenylalanine on the activity of human TRYPTOPHAN HYDROXYLASE –2 : comparison with that on tyrosine HYDROXYLASE activity
      85. TRYPTOPHAN HYDROXYLASE –2 gene polymorphisms in rhesus monkeys: association with hypothalamic–pituitary–adrenal axis function and in vitro gene …
      86. Estrogen receptor‐β regulates human TRYPTOPHAN HYDROXYLASE ‐2 through an estrogen response element in the 5′ untranslated region
      87. Influence of functional TRYPTOPHAN HYDROXYLASE 2 gene variation and sex on the startle response in children, young adults, and older adults
      88. Phosphorylation and activation of TRYPTOPHAN HYDROXYLASE 2 : identification of serine‐19 as the substrate site for calcium, calmodulin‐dependent protein kinase II
      89. A Novel Interaction between TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) Gene Polymorphism (rs457062 5) and BDNF Val66Met Predicts a High-Risk Emotional …
      90. Genetic variants in the TRYPTOPHAN HYDROXYLASE 2 gene (TPH2 ) and depression during and after pregnancy
      91. Support for TRYPTOPHAN HYDROXYLASE –2 as a susceptibility gene for bipolar affective disorder
      92. SNP-and haplotype analysis of the TRYPTOPHAN HYDROXYLASE 2 gene in alcohol-dependent patients and alcohol-related suicide
      93. Lipidomic profiling of TRYPTOPHAN HYDROXYLASE 2 knockout mice reveals novel lipid biomarkers associated with serotonin deficiency
      94. A detailed association analysis between the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene and autism spectrum disorders in a Japanese population
      95. Effect of TRYPTOPHAN HYDROXYLASE –2 gene polymorphism G-703 T on personality in a population representative sample
      96. GENETIC STUDY: Analysis of variations in the TRYPTOPHAN HYDROXYLASE ‐2 (TPH2 ) gene in cocaine dependence
      97. … deficiency during perinatal development increases serotonin turnover in the prefrontal cortex and decreases midbrain TRYPTOPHAN HYDROXYLASE –2 expression in adult …
      98. Impact of TRYPTOPHAN HYDROXYLASE 2 G-703T polymorphism on anger-related personality traits and orbitofrontal cortex
      99. TRYPTOPHAN HYDROXYLASE 2 (TPH 2 ) single nucleotide polymorphisms, suicide, and alcohol-related suicide
      100. The C1473G polymorphism in the TRYPTOPHAN HYDROXYLASE –2 gene: Involvement in ethanol-related behavior in mice
      101. Gender differences in TRYPTOPHAN HYDROXYLASE –2 mRNA, serotonin, and 5-hydroxyTRYPTOPHAN levels in the brain of catfish, Clarias gariepinus, during sex differentiation
      102. Serotonin (5-HT) in the regulation of depression-related emotionality: insight from 5-HT transporter and TRYPTOPHAN HYDROXYLASE –2 knockout mouse models
      103. TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms predict brain serotonin synthesis in the orbitofrontal cortex in humans
      104. Poststroke emotional disturbances and a TRYPTOPHAN HYDROXYLASE 2 gene polymorphism
      105. Identifying patients with major depressive disorder based on TRYPTOPHAN HYDROXYLASE –2 methylation using machine learning algorithms
      106. Association of polymorphisms of the TRYPTOPHAN HYDROXYLASE 2 gene with risk for bipolar disorder or suicidal behavior
      107. Gene expression of TRYPTOPHAN HYDROXYLASE 2 in post-mortem brain of suicide subjects
      108. Lithium modulates TRYPTOPHAN HYDROXYLASE 2 gene expression and serotonin release in primary cultures of serotonergic raphe neurons
      109. Regulation of TRYPTOPHAN HYDROXYLASE –2 gene expression by a bipartite RE-1 silencer of transcription/neuron restrictive silencing factor (REST/NRSF) binding motif
      110. Investigation of TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) in schizophrenia and in the response to antipsychotics
      111. Association between TRYPTOPHAN HYDROXYLASE 2 polymorphism and anger-related personality traits among young Korean women
      112. Association between TRYPTOPHAN HYDROXYLASE –2 gene and late-onset depression
      113. TRYPTOPHAN HYDROXYLASE 2 aggregates through disulfide cross‐linking upon oxidation: possible link to serotonin deficits and non‐motor symptoms in Parkinson’s …
      114. GENETIC STUDY: TRYPTOPHAN HYDROXYLASE 2 gene and alcohol use among college students
      115. Methylation of the TRYPTOPHAN HYDROXYLASE ‑2 gene is associated with mRNA expression in patients with major depression with suicide attempts
      116. Variation in TRYPTOPHAN HYDROXYLASE –2 gene is not associated to male completed suicide in Estonian population
      117. Decreased TRYPTOPHAN HYDROXYLASE 2 mRNA and protein expression, decreased brain serotonin concentrations, and anxiety-like behavioral changes in a rat model of …
      118. … equine estrogens have differential effects on cognitive, anxiety-like, and depressive-like behaviors and increase TRYPTOPHAN HYDROXYLASE –2 mRNA levels in …
      119. Association between TRYPTOPHAN HYDROXYLASE –2 genotype and the antidepressant effect of citalopram and paroxetine on immobility time in the forced swim test in mice
      120. Stimulation of 5-HT 2 C receptors improves cognitive deficits induced by human TRYPTOPHAN HYDROXYLASE 2 loss of function mutation
      121. Interaction of TRYPTOPHAN HYDROXYLASE 2 gene and life events in susceptibility to major depression in a Chinese Han population
      122. … among within-litter differences in early mothering received and later emotional behaviors, mothering, and cortical TRYPTOPHAN HYDROXYLASE –2 expression in female …
      123. Social approach, anxiety, and altered TRYPTOPHAN HYDROXYLASE 2 activity in juvenile BALB/c and C57BL/6J mice
      124. Cell‐type specific induction of TRYPTOPHAN HYDROXYLASE ‐2 transcription by calcium mobilization
      125. Food anticipatory activity on circadian time scales is not dependent on central serotonin: evidence from TRYPTOPHAN HYDROXYLASE –2 and serotonin transporter …
      126. Rhesus monkey TRYPTOPHAN HYDROXYLASE –2 coding region haplotypes affect mRNA stability
      127. … juvenile “babysitting” facilitates later adult maternal responsiveness, decreases anxiety, and increases dorsal raphe TRYPTOPHAN HYDROXYLASE ‐2 expression in female …
      128. … differences in basal and post‐citalopram extracellular 5‐HT in the mouse medial prefrontal cortex and dorsal hippocampus: relation with TRYPTOPHAN HYDROXYLASE ‐2 …
      129. TRYPTOPHAN HYDROXYLASE 2 gene is associated with cognition in late-onset depression in a Chinese Han population
      130. A case-control association study of serotonin 1A receptor gene and TRYPTOPHAN HYDROXYLASE 2 gene in attention deficit hyperactivity disorder
      131. No genetic association between TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms and Japanese schizophrenia
      132. C1473G polymorphism in mouse TRYPTOPHAN HYDROXYLASE –2 gene in the regulation of the reaction to emotional stress
      133. Role of the Allelic Variation in the 5-Hydroxytryptamine Receptor 1A (HTR1A) and the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) Genes in the Development of PTSD
      134. To cheat or not to cheat: TRYPTOPHAN HYDROXYLASE 2 snp variants contribute to dishonest behavior
      135. Influence of human TRYPTOPHAN HYDROXYLASE 2 N‐and C‐terminus on enzymatic activity and oligomerization
      136. Association study of TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms in bipolar disorder patients with panic disorder comorbidity
      137. Evaluation of blood‑brain barrier permeability in TRYPTOPHAN HYDROXYLASE 2 ‑knockout mice
      138. Alcoholics have more TRYPTOPHAN HYDROXYLASE 2 mRNA and protein in the dorsal and median raphe nuclei
      139. Effect of photoperiodic alterations on depression-like behavior and the brain serotonin system in mice genetically different in TRYPTOPHAN HYDROXYLASE 2 activity
      140. Emotion appraisal and the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene
      141. Additive effects of 5-HTTLPR (serotonin transporter) and TRYPTOPHAN HYDROXYLASE 2 G-703T gene polymorphisms on the clinical response to citalopram among children …
      142. No effect of C1473G polymorphism in the TRYPTOPHAN HYDROXYLASE 2 gene on the response of the brain serotonin system to chronic fluoxetine treatment in mice
      143. Cerebral 5-HT2 A receptor binding, but not mGluR2 , is increased in TRYPTOPHAN HYDROXYLASE 2 decrease-of-function mice
      144. Genetic variation in the TRYPTOPHAN HYDROXYLASE 2 gene moderates depressive symptom trajectories and remission over 8 weeks of escitalopram treatment
      145. Ultrastructural characterization of TRYPTOPHAN HYDROXYLASE 2 -specific cortical serotonergic fibers and dorsal raphe neuronal cell bodies after MDMA treatment in rat
      146. Deficiency of Serotonin in Raphe Neurons and Altered Behavioral Responses in TRYPTOPHAN HYDROXYLASE 2 -Knockout Medaka (Oryzias latipes)
      147. Family-based association study of TRYPTOPHAN HYDROXYLASE 2 and serotonin 1A receptor genes in attention deficit hyperactivity disorder
      148. Altered TRYPTOPHAN HYDROXYLASE 2 expression in enteric serotonergic nerves in Hirschsprung’s-associated enterocolitis
      149. Targeted manipulation of brain serotonin: RNAi-mediated knockdown of TRYPTOPHAN HYDROXYLASE 2 in rats
      150. Associations between polymorphic variants of the TRYPTOPHAN HYDROXYLASE 2 gene and obsessive-compulsive disorder
      151. Altered expression of neuronal TRYPTOPHAN HYDROXYLASE –2 mRNA in the dorsal and median raphe nuclei of three genetically modified mouse models relevant to …
      152. Functional characterization of the S41Y (C2 755A) polymorphism of TRYPTOPHAN HYDROXYLASE 2
      153. Hypotensive but not normotensive haemorrhage increases TRYPTOPHAN HYDROXYLASE –2 mRNA in caudal midline medulla
      154. TRYPTOPHAN HYDROXYLASE 2 Deficiency Modifies the Effects of Fluoxetine and Pargyline on the Behavior, 5-HT-and BDNF-Systems in the Brain of Zebrafish (Danio rerio)
      155. TRYPTOPHAN HYDROXYLASE 2 gene polymorphism in anxiety and depressive disorder in Kashmiri population
      156. Genetic Variants and Haplotypes of TRYPTOPHAN HYDROXYLASE 2 and Reelin Genes May Be Linked with Attention Deficit Hyperactivity Disorder in Egyptian Children
      157. Association between lifelong premature ejaculation and polymorphism of TRYPTOPHAN HYDROXYLASE 2 gene in the Han population
      158. A two-stage case-control association study between the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene and schizophrenia in a Japanese population
      159. 3, 4-Methylenedioxymethamphetamine induces differential regulation of TRYPTOPHAN HYDROXYLASE 2 protein and mRNA levels in the rat dorsal raphe nucleus
      160. Involvement of TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) gene polymorphisms in susceptibility to coronary artery lesions in Korean children with Kawasaki disease
      161. Functional characterization of the neuron‐restrictive silencer element in the human TRYPTOPHAN HYDROXYLASE 2 gene expression
      162. A new gain-of-function allele in chimpanzee TRYPTOPHAN HYDROXYLASE 2 and the comparison of its enzyme activity with that in humans and rats
      163. Functional gene variants of the serotonin-synthesizing enzyme TRYPTOPHAN HYDROXYLASE 2 in migraine
      164. Physical weight loading induces expression of TRYPTOPHAN HYDROXYLASE 2 in the brain stem
      165. Response to correspondence: loss-of-function mutation in TRYPTOPHAN HYDROXYLASE –2 identified in unipolar major depression
      166. Endogenous Deficiency of Brain-Derived Neurotrophic Factor Induces the Downregulation of TRYPTOPHAN HYDROXYLASE –2 Expression in Raphe Nuclei of Rapid …
      167. 5′-Untranslated region of the TRYPTOPHAN HYDROXYLASE –2 gene harbors an asymmetric bidirectional promoter but not internal ribosome entry site in vitro
      168. #VALUE!
      169. #VALUE!
      170. TRYPTOPHAN HYDROXYLASE –2 polymorphism is associated with white matter integrity in first-episode, medication-naïve major depressive disorder patients
      171. Stabilization of TRYPTOPHAN HYDROXYLASE 2 by l‐phenylalanine‐induced dimerization
      172. Comprehensive behavioral analysis and quantification of brain free amino acids of C57 BL/6J congenic mice carrying the 1473G allele in TRYPTOPHAN HYDROXYLASE ‐2
      173. Involvement of TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms in susceptibility to tic disorder in Chinese Han population
      174. Cigarette smoking and TRYPTOPHAN HYDROXYLASE 2 mRNA in the dorsal raphe nucleus in suicides
      175. Genetic variability in TRYPTOPHAN HYDROXYLASE 2 gene in alcohol dependence and alcohol-related psychopathological symptoms
      176. The effect of diet-induced and melanocortin obesity on expression of TRYPTOPHAN HYDROXYLASE 2 in the dorsal raphe nucleus and ventral tegmental area in mice
      177. The relationship between TRYPTOPHAN HYDROXYLASE –2 gene with primary insomnia and depressive symptoms in the Han Chinese population
      178. Association analysis of the TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms in patients with methamphetamine dependence/psychosis
      179. The C1473G polymorphism in gene tph2 is the main factor mediating the genetically defined variability of TRYPTOPHAN HYDROXYLASE –2 activity in the mouse brain
      180. … on the expression of the Bdnf, Bax, Bcl-xL, and CASP3 genes in the mouse brain: Role of the C1473G polymorphism in the gene encoding TRYPTOPHAN HYDROXYLASE 2
      181. Effect of Chaihu Shugan Powder on the content of 5-hydroxytryptamine and the expression of TRYPTOPHAN HYDROXYLASE 2 in depression rats
      182. No association between TRYPTOPHAN HYDROXYLASE –2 gene G1463A polymorphism and unipolar depression in a Southern Chinese Han population (translated version)
      183. Association of TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms with major depression disorder and antidepressant treatment response
      184. Differential tissue distribution of TRYPTOPHAN HYDROXYLASE isoforms 1 and 2 as revealed with monospecific antibodies
      185. Electrophysiological investigation of two animal models for emotional disorders-serotonin transporter knockout mice and TRYPTOPHAN HYDROXYLASE 2 knockout mice
      186. TRYPTOPHAN HYDROXYLASE 2 and Bcl-xL in the rat raphe nucleus after acute and chronic forced swim stress
      187. The upregulation of TRYPTOPHAN HYDROXYLASE ‐2 expression is important for premature ejaculation treatment with the selective serotonin reuptake inhibitor
      188. TRYPTOPHAN HYDROXYLASE –2 immunoreactivity changes in the dorsal raphe nucleus after chronic methamphetamine or corticosterone in BDNF-deficient mice models …
      189. Altered 3D Structure of Human TRYPTOPHAN HYDROXYLASE –2 Caused by Change in the amino acid 341: In Silico Analysis
      190. Impact of genetic variability in the serotonin transporter, TRYPTOPHAN HYDROXYLASE –2 , and serotonin 2 A receptors on MDMA use and impulsivity
      191. Structural and functional determinants of human TRYPTOPHAN HYDROXYLASE 2 activity
      192. Association between SNPs in the promoter region of the TRYPTOPHAN HYDROXYLASE 2 gene (TPH2 ) and the hypothalamic-pituitary-adrenocortical (HPA) axis …
      193. TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) Gene in Bipolar I Disorder in the Romanian Population
      194. Anti-Phospho-Ser 19 TRYPTOPHAN HYDROXYLASE 2
      195. Transcriptional regulation of TRYPTOPHAN HYDROXYLASE –2
      196. REGULATION OF THE NEURONAL-SPECIFIC TRYPTOPHAN HYDROXYLASE –2
      197. TRYPTOPHAN HYDROXYLASE 2 gene polymorphisms and poststroke anxiety disorders
      198. Upregulation in the Expression of TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) in the Lower Brainstem in Depression
      199. Modulation of arousal state and temperature is unaltered but activity is increased in TRYPTOPHAN HYDROXYLASE 2 knockout mice (1130.5)
      200. Inducible TRYPTOPHAN HYDROXYLASE 2 knockout mice as model for anxiety and fear like behaviour
      201. PRO2 06SER AND ARG441HIS MUTATIONS INFLUENCE ON HUMAN TRYPTOPHAN HYDROXYLASE 2 ACTIVITY–A MOLECULAR MODELING STUDY
      202. Characterisation of three polymorphisms of the TRYPTOPHAN HYDROXYLASE 2 gene in a sample of Colombian population with major depressive disorder
      203. Polymorphism of the TRYPTOPHAN HYDROXYLASE 2 (TPH2 ) Gene Is Associated with Chimpanzee Neuroticism. PLoS ONE6 (7): e22144
      204. Behavioral, neuronal, and development consequences of genetically decreased TRYPTOPHAN HYDROXYLASE 2 activity
      205. Behavioral and physiologic consequences of inducible inactivation of the\(TRYPTOPHAN\)\(HYDROXYLASE \) 2 gene in interaction with early-life adversity
      206. Genomic TRYPTOPHAN HYDROXYLASE 2 (Tph2 ) Mutation in Rats Increases Mortality and Disrupts Eupneic Breathing During Postnatal Development
      207. Ventilatory long‐term facilitation is altered in TRYPTOPHAN HYDROXYLASE 2 knock out mice
      208. The TRYPTOPHAN HYDROXYLASE 2 (Tph2 ) polymorphism C2 432 T mediates wound repair and behavioral responses to SSRIs in a sex‐specific manner
      209. The TRYPTOPHAN HYDROXYLASE 2 (Tph2 ) polymorphism C2 432 T mediates mRNA expression and responses to antidepressant treatment in a sex‐specific manner
      210. Effects of moxibustion on the expression of TRYPTOPHAN HYDROXYLASE 2 mRNA and the activity of monoamine oxidase in depression model rats
      211. Circadian gene expression of TRYPTOPHAN HYDROXYLASE 2 in the dorsal and median raphe nuclei is altered by dysregulated glucocorticoid rhythms
      212. Effects of genetic deficiency of TRYPTOPHAN HYDROXYLASE 2 on attentional processes in the five choice serial reaction time task in rats
      213. THE ROLE OF 5′-UNTRANSLATED REGION OF THE HUMAN TRYPTOPHAN HYDROXYLASE 2 IN THE REGULATION OF GENE EXPRESSION IN …
      214. TRYPTOPHAN HYDROXYLASE 2 G703T polymorphism and the temperament and character in a Korean population
      215. Association between Attention Deficit Hyperactivity Disorder and Single Nucleotide Polymorphisms of TRYPTOPHAN HYDROXYLASE 2 Gene
      216. Vitamin D Stimulates Serotonin Production via Induction of the TRYPTOPHAN HYDROXYLASE 2 Isoform in B14 Rat Medullary Neurons
      217. An association study on interaction of single nucleotide polymorphism of TRYPTOPHAN HYDROXYLASE 2 with negative life events on major depressive disorder
      218. Additive effects of serotonin transporter and the TRYPTOPHAN HYDROXYLASE –2 gene variation on emotional processing.
      219. P03-365-Association study of TRYPTOPHAN HYDROXYLASE –2 gene in schizophrenia and its clinical features in chinese han population
      220. Polymorphisms in TRYPTOPHAN HYDROXYLASE 2 leading to decreased serotonergic activity contribute to elevated risk for metabolic syndrome in depression
      221. Association study of interaction of TRYPTOPHAN HYDROXYLASE 2 with serotonin 1A receptor gene polymorphism on major depressive disorder
      222. Association Study between TRYPTOPHAN HYDROXYLASE 2 Gene-703G/T Polymorphism and Tardive Dyskinesia
      223. Presynaptic localization of TRYPTOPHAN HYDROXYLASE 2 in mature hippocampal neurons
      224. Effects of antidepressant therapy on serotonin and TRYPTOPHAN HYDROXYLASE 2 in ovariectomized rats with depressive disorder
      225. Association analysis of TRYPTOPHAN HYDROXYLASE –2 gene polymorphism with antisocial personality disorder and impulsivity
      226. Genetic risk factors for suicide in major depression: a focus on the serotonin transporter and TRYPTOPHAN HYDROXYLASE –2 genes
      227. Effect of ketamine on expression of TRYPTOPHAN HYDROXYLASE 2 in median raphe nuclei of mentally depressed mice
      228. TRYPTOPHAN HYDROXYLASE type 2 variants modulate severity and outcome of addictive behaviors in Parkinson’s disease
      229. Rats deficient in TRYPTOPHAN HYDROXYLASE 2 (SSTph2 −/− rats) show altered pulmonary neuroendocrine cells (PNECs), reduced resting ventilation and altered hypoxic …
      230. Lithium augmentation in treatment-resistant depression: influence of polymorphisms in TRYPTOPHAN HYDROXYLASE 2 gene (TPH2 ) on therapy response
      231. Behavioral effects of estrogen receptor beta acting locally to regulate the expression of TRYPTOPHAN HYDROXYLASE 2 (THP2 ) in serotonergic neurons of the dorsal raphe …
      232. The TRYPTOPHAN HYDROXYLASE (TPH) 2 gene unlike TPH-1 exhibits no association with stress-induced depression
      233. Association of interaction of TRYPTOPHAN HYDROXYLASE isoform (TPH-2 ) genes with uniplor deression
      234. Associations between prefrontal γ-aminobutyric acid concentration and the TRYPTOPHAN HYDROXYLASE isoform 2 gene, a panic disorder risk allele in women
      235. Molecular cloning, characterization and expression of two TRYPTOPHAN HYDROXYLASE (TPH-1 and TPH-2 ) genes in the hypothalamus of Atlantic croaker: down-regulation …
      236. Topographical distribution of corticotropin-releasing factor type 2 receptor-like immunoreactivity in the rat dorsal raphe nucleus: co-localization with TRYPTOPHAN …
      237. TRYPTOPHAN HYDROXYLASE isoforms 1 and 2 : Functional characterization, tissue distribution and posttranslational modification
      238. Acetylation of Phenylalanine HYDROXYLASE and TRYPTOPHAN 2 , 3-Dioxygenase Alters Hepatic Aromatic Amino Acid Metabolism in Weaned Piglets
      239. Increased expression of TRYPTOPHAN-5-HYDROXYLASE 1, but not 2 , in brainstem as a result of intrauterine malnutrition

       

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