• SHOP
    • COMBOS
    • TESTIMONIALS
    • CART
    • INGREDIENTS
      • 2-DEOXY-D-GLUCOSE (2DG)
      • ACACIA CYANOPHYLLA FLOWER
      • ACORI GRAMINEI RHIZOMA
      • AEGLE MARMELOS CORREA
      • AGARICUS BLAZEI
      • AGED GARLIC EXTRACT
      • AFRAMOMUM MELEGUETA
      • ALOE ARBORESCENS
      • ALBIZIA
      • ALPINIA OFFICINARUM
      • ALTERNANTHERA SESSILIS
      • AMERICAN GINSENG
      • AMYGDALIN
      • ANACYCLUS PYRETHRUM
      • ANGELICA ARCHANGELICA
      • ANGELICA SINENSIS
      • ANTRODIA
      • APIGENIN
      • ARTICHOKE LEAF
      • ARTOCARPIN
      • AJUGA TURKESTANICA
      • ASHWAGANDHA
      • ASPALATHIN
      • ASTRAGALUS COMPLANATUS
      • AVENA SATIVA
      • BACOPA MONNIERI
      • BAVACHIN
      • BEE POLLEN
      • BETULINIC ACID
      • BOSWELLIC ACID
      • BREVILIN A
      • CAMPESTEROL
      • CAPSAICIN
      • CARCININE
      • CASTICIN
      • CHRYSIN
      • CIANIDANOL
      • CINNAMOMUM ZEYLANICUM
      • CITRULLUS COLOCYNTHIS
      • CITRUS RETICULATA PEEL
      • CODONOPSIS
      • CONJUGATED LINOLEIC ACID
      • COSTUNOLIDE
      • CYANIDIN
      • CUCURBITACIN D
      • DAIDZEIN
      • DECURSIN
      • DELPHINIDIN
      • DIGITALIS PURPREA (DIGOXIN)
      • DIOSMIN
      • ELLAGIC ACID
      • EMBELIN
      • ERIODICTYOL
      • GALLIC ACID
      • GLYCITEIN
      • GLYCYRRHIZIN
      • HYPERFORIN
      • ICARIIN
      • ISORHAMNETIN
      • ISOORIENTIN
      • ISOVITEXIN
      • JACEOSIDIN
      • KAEMPFEROL
      • KIGELIA AFRICANA
      • KURARINONE
      • LEMON BALM
      • LICORICIDIN
      • LIPOIC ACID
      • LUPEOL
      • MAGNOLOL
      • MULBERRY LEAF
      • NARINGENIN
      • NOBILETIN
      • OLEACEIN
      • OLEANOLIC ACID
      • OLIVE OIL
      • ORIDONIN
      • PARTHENOLIDE
      • PHLOROGLUCINOL
      • PHLORIZIN
      • PICEATANNOL
      • PRISTIMERIN
      • PROANTHOCYANIDINS
      • PROCYANIDIN B3
      • PSEUDOLARIC ACID B
      • PTEROSTILBENE
      • RUTIN
      • SOLIDAGO VIRGAUREA
      • TANGERETIN
      • TARAXASTEROL
      • TRICHOSTATIN A
      • WEDELOLACTONE
      • WOGONIN
      • YERBA MATE
    • ABOUT
    • SCIENTIFIC STUDIES
      • ADAPTOGENS
      • ADIPOCYTE APOPTOSIS (KILLING FAT CELLS)
      • ADDICTION AND THE BRAIN
      • ADDICTION & STRESS
      • ADDICTION WITHDRAWAL
      • ADIPOCYTE DEDIFFERENTIATION (THE REVERSAL OF FAT FORMATION)
      • ADIPOCYTE DIFFERENTIATION
      • ALLERGIES & CYTOKINES
      • ALDOSTERONE & OBESITY/HYPERTENSION
      • ALZHEIMER’S, DEMENTIA, PARKINSON’S
      • ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS
      • ADVANCED GLYCATION END PRODUCTS (AGES)
      • ADDICTION TREATMENT
      • AMPK
      • ANTI AGING
      • ANTIAGING EFFECTS OF COFFEE
      • ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-APOPTOTIC PATHWAYS
      • ANTI ATHEROGENIC
      • ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI CARIOGENIC (Protecting From Tooth Decay)
      • ANTI COVID-19 EFFECTS OF MEDICINAL PLANTS, FLAVONOIDS & POLYPHENOLS
      • ANTI GLYCATIVE
      • ANTI GLYCATION AGENTS
      • ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI WRINKLE AGENTS
      • APOPTOSIS
      • APOPTOSIS IN 3T3-L1
      • AUTOPHAGY
      • BCL-2
      • BCL-W
      • BCL-XL
      • BDNF
      • BECLIN-1 & AUTOPHAGY
      • BH3 MIMETICS
      • BIM aka BCL2L11
      • BMI-1
      • BRASSINOSTEROIDS
      • CALORIE RESTRICTION
      • CALORIE RESTRICTION & LIFESPAN EXTENSION
      • CARBAMYLATION
      • CARBONYL SCAVENGER
      • CARBONYL STRESS
      • CARDIOPROTECTIVE AGENTS
      • CARDIAC GLYCOSIDES
      • CATALASE
      • CELL CYCLE ARREST
      • CENTENARIANS
      • CHOLESTEROL EFFLUX
      • COGNITIVE ENHANCEMENT
      • COLD SHOCK PROTEINS
      • COLD-INDUCIBLE RNA-BINDING PROTEIN (CIRBP) & DNA REPAIR
      • CONDITIONED PLACE PREFERENCE
      • CORTICOTROPIN RELEASING FACTOR
      • CRYOTHERAPY
      • CRYOLIPOLYSIS: FREEZING FAT TO DEATH
      • CYP2E1
      • CYTOKINES IN PAIN, INFLAMMATION & AGING
      • DAF-16
      • DIABETES & CANCER
      • DIHYDROTESTOSTERONE (DHT)
      • DNA METHYLATION & AGING
      • DNA REPAIR
      • DNA REPAIR VIA FLAVONOIDS & POLYPHENOLS
      • ADDICTION & DOPAMINE
      • DRY FASTING AND FLUID RESTRICTION FASTING
      • DYNORPHIN
      • ELLAGITANNINS
      • ENLARGED HEART AND CARDIOMEGALY
      • EPIGENETIC MODIFIERS
      • EPINEPHRINE
      • ERGOGENIC AGENTS (INCREASE ATHLETIC PERFORMANCE)
      • EXCITOXICITY & THE BRAIN
      • EXTRACELLULAR MATRIX STIFFENING (10TH HALLMARK OF AGING)
      • EXTENDS LIFESPAN
      • EXTINCTION TRAINING
      • FASTING BRAIN
      • FASTING CANCER
      • FASTING & CANCER
      • FASTING MIMICKING DIET
      • FEAR EXTINCTION
      • FGF21
      • FLAVONES
      • GABA (γ-AMINOBUTYRIC ACID)
      • GALLOTANNINS
      • GLUCONEOGENESIS
      • GLUTAMATE & BRAIN
      • GLYCATION
      • KLOTHO
      • FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN
      • FOXO3
      • FOXO4
      • HALLMARKS OF AGING
      • HEPATOPROTECTIVE AGENTS (KEEPING LIVER HEALTHY)
      • HMGB1
      • HORMESIS
      • HPA AXIS
      • HSP70, THE ANTI-AGING PROTEIN
      • HSP90 INHIBITORS
      • HYPERGLYCEMIA
      • HYPERINSULINEMIA
      • HYPOACTIVE SEXUAL DESIRE (WHY PEOPLE HAVE ZERO SEX DRIVE)
      • HYPOCRETIN OREXIN
      • IKK
      • IL-6/STAT3
      • IRISIN
      • ISOFLAVONES
      • IMMUNOSENESCENCE
      • INCREASE PROTEIN SYNTHESIS
      • INFECTOBESITY
      • INFLAMMATION & ANXIETY
      • INFLAMMATION & CANCER
      • INFLAMMATION & DEPRESSION
      • INFLAMMATION & OBESITY
      • INFLAMMAGING
      • INHIBITION OF RENAL GLUCOSE REABSORPTION
      • INSULIN & AGING
      • INSULIN & CANCER: HOW INSULIN LITERALLY PROTECTS CANCER CELLS FROM BEING KILLED
      • INSULIN & MTOR
      • INSULIN & OBESITY
      • INTERMITTENT FASTING
      • JAK INHIBITION ALLEVIATES SASP
      • JNK ACTIVATION PREVENTS PREMATURE SENESCENCE
      • KETONE BODIES
      • KETOGENIC DIET
      • LEYDIG CELL STEROIDOGENESIS
      • LIFESPAN EXTENSION
      • LIPOLYTIC AGENTS
      • LIPID DROPLETS
      • LIPOLYSIS (THE DECOMPOSITION OF BODY FAT)
      • LOWERING CHOLESTEROL THRU FASTING, DIET & MEDICINAL PLANTS
      • MATRIX METALLOPROTEINASES (MMPs)
      • MCL-1
      • MDM2 INHIBITION AS SASP INHIBITOR
      • MEDITERRANEAN DIET
      • MENAQUINONE 4
      • METABOLIC REPROGRAMMING
      • METABOLIC SYNDROME EXTRACT
      • METHIONINE RESTRICTION
      • MITOCHONDRIAL UNCOUPLING
      • MONKEYPOX
      • MSG (MONOSOSODIUM GLUTAMATE)
      • MUSCLE FORCE PRODUCTION
      • MUSCLE ATROPHY (PREVENTING)
      • MYOGENESIS
      • MYOSTATIN INHIBITION
      • MYOSTATIN INHIBITION PRESERVES MUSCLE
      • mTORC2
      • mTOR: THE RAPID AGING PATHWAY
      • NATURAL ANTICOAGULANTS
      • NATURAL AROMATASE INHIBITORS
      • NEUROGENESIS (GROWING NEW BRAIN CELLS)
      • NEUROCHEMISTRY OF ADDICTION
      • NEUROPLASTICITY
      • NEUROINFLAMMATION
      • NEUROPROTECTIVE AGENTS
      • NMDA & ANXIETY & DEPRESSION
      • NMDA RECEPTOR AND FEAR
      • NON-OPIOID ANALGESICS (PLANT BASED)
      • NOOTROPICS
      • NORADRENERGIC
      • NOREPINEPHRINE
      • NRF2: MASTER REGULATOR OF THE AGING PROCESS
      • NF-KB
      • ONCOGENE ACTIVATION INDUCED SENESCENCE
      • OVERNUTRITION
      • OXIDATIVE STRESS & AGING
      • P16INK4A
      • P38MAPK
      • P53: TUMOR SUPRESSOR
      • PERIODONTITIS
      • PHYTOCHEMICALS
      • PHYTOSTEROLS
      • PHYTOSTANOLS
      • PHYTOECDYSTEROIDS
      • PROANTHOCYANIDINS
      • PROTEIN CARBONYLATION
      • POLYAMINES & THEIR EFFECT ON BRAIN (NMDA, DEPRESSION, SUICIDE RISK)
      • PPARY2
      • PREMATURE SENESCENCE
      • PREVENTING SKIN AGING
      • PUFAS
      • PURGATIVES
      • RAPAMYCIN (MTOR INHIBITION)
      • RECEPTOR “Κ OPIOID”
      • RED WINE
      • RENAL (KIDNEY) PROTECTIVE AGENTS
      • REMINERALIZATION OF TEETH
      • REPAIR OF DNA BREAKS “DOUBLE STRAND”
      • RESTORE INSULIN SENSITIVITY
      • SASP & ADIPOSE TISSUE
      • SENESCENT CELLS, SASP & SENOLYTICS
      • SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG)
      • SGLT2 INHIBITORS
      • SGLT2 INHIBITION FOR LIFESPAN EXTENSION
      • SHBG
      • SIRT1
      • SKELETAL MUSCLE HYPERTROPHY (THE SCIENCE OF BUILDING MUSCLE)
      • SKIN ELASTICITY
      • SKIN PHOTOAGING (Preventing & Repairing)
      • SLEEP DEPRIVATION AS THERAPY FOR DEPRESSION
      • SIRT1 & LONGEVITY
      • SMALLPOX
      • SUGAR & AGING
      • STAR PROTEIN
      • STAT3
      • STEM CELL EXHAUSTION
      • STEM CELL REGENERATION
      • STEM CELL THERAPY
      • STIMULATED LIPOLYSYS
      • STEROIDOGENESIS (THE PRODUCTION OF HORMONES IN BODY)
      • STREPTOCOCCUS MUTANS (MAIN BACTERIA BEHIND TOOTH DECAY)
      • STRESS & AGING
      • STRESS & THE BRAIN
      • TELOMERE SHORTENING & PREMATURE AGING
      • TIME RESTRICTED FEEDING
      • TRAUMATIC BRAIN INJURY (HEALING)
      • TRYPTOPHAN HYDROXYLASE 2
      • VISCERAL ADIPOSITY
    • HOME
    • CONTACT
    • INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL
    • The Ultimate Dry Fasting Resource
    0
    MENAQUINONE 4
    May 20, 2022
    CIANIDANOL
    June 1, 2022
    1. Overexpression of Atg5 in mice activates autophagy and extends lifespan
    2. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice
    3. Inhibition of mRNA translation extends lifespan in Caenorhabditis elegans
    4. Dietary deprivation extends lifespan in Caenorhabditis elegans
    5. An antidepressant that extends lifespan in adult Caenorhabditis elegans
    6. rAAV6-microdystrophin preserves muscle function and extends lifespan in severely dystrophic mice
    7. Increased fidelity of protein synthesis extends lifespan
    8. Loss of pregnancy‐associated plasma protein A extends lifespan in mice
    9. The SIRT1 activator SRT1720 extends lifespan and improves health of mice fed a standard diet
    10. 4E-BP extends lifespan upon dietary restriction by enhancing mitochondrial activity in Drosophila
    11. JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila
    12. Extracellular vesicle-contained eNAMPT delays aging and extends lifespan in mice
    13. Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
    14. D-beta-hydroxybutyrate extends lifespan in C. elegans
    15. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR
    16. Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino-acid status
    17. Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+
    18. PI3Kγ inhibition blocks glomerulonephritis and extends lifespan in a mouse model of systemic lupus
    19. Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice
    20. Restriction of amino acids extends lifespan in Drosophila melanogaster
    21. Rapamycin extends lifespan and delays tumorigenesis in heterozygous p53+/− mice
    22. Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
    23. Preventing age-related decline of gut compartmentalization limits microbiota dysbiosis and extends lifespan
    24. Dietary restriction extends lifespan through metabolic regulation of innate immunity
    25. Glycine supplementation extends lifespan of male and female mice
    26. Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in mice
    27. Lonicera japonica extends lifespan and healthspan in Caenorhabditis elegans
    28. Reduced circulating insulin enhances insulin sensitivity in old mice and extends lifespan
    29. Roux‐en‐Y gastric bypass enhances energy expenditure and extends lifespan in diet‐induced obese rats
    30. New nanoformulation of rapamycin Rapatar extends lifespan in homozygous p53−/− mice by delaying carcinogenesis
    31. The starvation hormone, fibroblast growth factor-21, extends lifespan in mice
    32. The endogenous ligand Stunted of the GPCR Methuselah extends lifespan in Drosophila
    33. Single-dose CRISPR–Cas9 therapy extends lifespan of mice with Hutchinson–Gilford progeria syndrome
    34. Deletion of the Mitochondrial Superoxide Dismutase sod-2 extends lifespan in Caenorhabditis elegans
    35. Human ApoD, an apolipoprotein up-regulated in neurodegenerative diseases, extends lifespan and increases stress resistance in Drosophila
    36. Depleting the methyltransferase Suv39h1 improves DNA repair and extends lifespan in a progeria mouse model
    37. The mitochondria-targeted antioxidant MitoQ extends lifespan and improves healthspan of a transgenic Caenorhabditis elegans model of Alzheimer disease
    38. The phytochemical, EGCG, extends lifespan by reducing liver and kidney function damage and improving age‐associated inflammation and oxidative stress in healthy …
    39. Royalactin extends lifespan of Caenorhabditis elegans through epidermal growth factor signaling
    40. Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome
    41. Methionine restriction extends lifespan in progeroid mice and alters lipid and bile acid metabolism
    42. Chemical activation of a food deprivation signal extends lifespan
    43. Growth hormone-releasing hormone disruption extends lifespan and regulates response to caloric restriction in mice
    44. Aspirin Inhibits Oxidant Stress, Reduces Age-Associated Functional Declines, and extends lifespan of Caenorhabditis elegans
    45. Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan
    46. Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria
    47. Grape extract protects mitochondria from oxidative damage and improves locomotor dysfunction and extends lifespan in a Drosophila Parkinson’s disease model
    48. Arginase-II deficiency extends lifespan in mice
    49. Silymarin extends lifespan and reduces proteotoxicity in C. elegans Alzheimer’s model
    50. Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice
    51. Crosstalk between cellular compartments protects against proteotoxicity and extends lifespan
    52. Mobilization‐based transplantation of young‐donor hematopoietic stem cells extends lifespan in mice
    53. The mitochondria-targeted antioxidant MitoQ inhibits memory loss, neuropathology, and extends lifespan in aged 3xTg-AD mice
    54. Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis
    55. An isocaloric moderately high-fat diet extends lifespan in male rats and Drosophila
    56. Overexpression of frataxin in the mitochondria increases resistance to oxidative stress and extends lifespan in Drosophila
    57. Sodium rutin extends lifespan and health span in mice including positive impacts on liver health
    58. Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer’s disease
    59. Lamotrigine extends lifespan but compromises health span in Drosophila melanogaster
    60. Inhibition of Cdc42 activity extends lifespan and decreases circulating inflammatory cytokines in aged female C57BL/6 mice
    61. Protocatechuic acid extends lifespan and increases stress resistance in Caenorhabditis elegans
    62. Mitochondrial stress extends lifespan in C. elegans through neuronal hormesis
    63. Chicoric Acid Is an Antioxidant Molecule That Stimulates AMP Kinase Pathway in L6 Myotubes and extends lifespan in Caenorhabditis elegans
    64. Autophagy induction extends lifespan and reduces lipid content in response to frataxin silencing in C. elegans
    65. PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila
    66. Phosphatidylcholine extends lifespan via DAF-16 and reduces amyloid-beta-induced toxicity in Caenorhabditis elegans
    67. Panax notoginseng polysaccharide increases stress resistance and extends lifespan in Caenorhabditis elegans
    68. Dietary nitrite extends lifespan and prevents age-related locomotor decline in the fruit fly
    69. L-Theanine extends lifespan of adult Caenorhabditis elegans
    70. Rebaudioside A enhances resistance to oxidative stress and extends lifespan and healthspan in Caenorhabditis elegans
    71. Drosophila insulin‐like peptide‐6 (dilp6) expression from fat body extends lifespan and represses secretion of Drosophila insulin‐like peptide‐2 from the brain
    72. Stimulating S-adenosyl-l-methionine synthesis extends lifespan via activation of AMPK
    73. Dietary Restriction extends lifespan in Wild-Derived Populations of Drosophila melanogaster
    74. The phytochemical glaucarubinone promotes mitochondrial metabolism, reduces body fat, and extends lifespan of Caenorhabditis elegans
    75. Systemic AAV9 gene transfer in adult GM1 gangliosidosis mice reduces lysosomal storage in CNS and extends lifespan
    76. S100A9 extends lifespan in insulin deficiency
    77. Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans
    78. The Drosophila homolog of methionine sulfoxide reductase A extends lifespan and increases nuclear localization of FOXO
    79. Vitamin E extends lifespan in the short-lived rotifer Asplanchna brightwelli
    80. Prohibitin depletion extends lifespan of a TORC2/SGK‐1 mutant through autophagy and the mitochondrial UPR
    81. Withania somnifera root extract extends lifespan of Caenorhabditis elegans
    82. Supplemental cellular protection by a carotenoid extends lifespan via Ins/IGF-1 signaling in Caenorhabditis elegans
    83. Ginsenoside extract from ginseng extends lifespan and health span in Caenorhabditis elegans
    84. Genetic reduction of mTOR extends lifespan in a mouse model of Hutchinson‐Gilford Progeria syndrome
    85. Increased uncoupling protein (UCP) activity in Drosophila insulin-producing neurons attenuates insulin signaling and extends lifespan
    86. Genetic inhibition of an ATP synthase subunit extends lifespan in C. elegans
    87. Near-infrared light increases ATP, extends lifespan and improves mobility in aged Drosophila melanogaster
    88. Guanabenz delays the onset of disease symptoms, extends lifespan, improves motor performance and attenuates motor neuron loss in the SOD1 G93A mouse model …
    89. Purple sweet potato extract extends lifespan by activating autophagy pathway in male drosophila melanogaster
    90. A novel antioxidant peptide purified from defatted round scad (Decapterus maruadsi) protein hydrolysate extends lifespan in Caenorhabditis elegans
    91. Grape skin extract improves muscle function and extends lifespan of a Drosophila model of Parkinson’s disease through activation of mitophagy
    92. A deuterohemin peptide extends lifespan and increases stress resistance in Caenorhabditis elegans
    93. Pyrroloquinoline quinone enhances the resistance to oxidative stress and extends lifespan upon DAF-16 and SKN-1 activities in C. elegans
    94. Rhodiola rosea extends lifespan and improves stress tolerance in silkworm, Bombyx mori
    95. Maintenance of protein homeostasis in glia extends lifespan in C. elegans
    96. N-Acetylcysteine extends lifespan of Drosophila via modulating ROS scavenger gene expression
    97. … red wine consumption increases the expression of longevity-associated genes in controlled human populations and extends lifespan in Drosophila melanogaster
    98. Telomerase therapy reverses vascular senescence and extends lifespan in progeria mice
    99. Steroid hormones sulfatase inactivation extends lifespan and ameliorates age-related diseases
    100. The absence of a mitochondrial genome in rho0 yeast cells extends lifespan independently of retrograde regulation
    101. Verapamil extends lifespan in Caenorhabditis elegans by inhibiting calcineurin activity and promoting autophagy
    102. A reduction in age-enhanced gluconeogenesis extends lifespan
    103. Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy
    104. Lonidamine extends lifespan of adult Caenorhabditis elegans by increasing the formation of mitochondrial reactive oxygen species
    105. An antidiabetic polyherbal phytomedicine confers stress resistance and extends lifespan in Caenorhabditis elegans
    106. Cyclin‐dependent kinase inhibition limits glomerulonephritis and extends lifespan of mice with systemic lupus
    107. Carnitine promotes recovery from oxidative stress and extends lifespan in C. elegans
    108. Emodin extends lifespan of Caenorhabditis elegans through insulin/IGF-1 signaling pathway depending on DAF-16 and SIR-2.1
    109. PBT2 reduces toxicity in a C. elegans model of polyQ aggregation and extends lifespan, reduces striatal atrophy and improves motor performance in the R6/2 mouse …
    110. The Yang-tonifying herbal medicine cynomorium songaricum extends lifespan and delays aging in drosophila
    111. 17‐a‐estradiol late in life extends lifespan in aging UM‐HET3 male mice; nicotinamide riboside and three other drugs do not affect lifespan in either sex
    112. Resveratrol extends lifespan and preserves glia but not neurons of the Nothobranchius guentheri optic tectum
    113. Metolazone upregulates mitochondrial chaperones and extends lifespan in Caenorhabditis elegans
    114. Genistein from Vigna angularis extends lifespan in Caenorhabditis elegans
    115. Sesamin extends lifespan through pathways related to dietary restriction in Caenorhabditis elegans
    116. MicroRNA-455-3p improves synaptic, cognitive functions and extends lifespan: Relevance to Alzheimer’s disease
    117. … of Streblus asper leaves protects against glutamate-induced toxicity in HT22 hippocampal neuronal cells and extends lifespan of Caenorhabditis elegans
    118. Overexpression of pink1 or parkin in indirect flight muscles promotes mitochondrial proteostasis and extends lifespan in Drosophila melanogaster
    119. Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice
    120. Korean red ginseng tonic extends lifespan in D. melanogaster
    121. Proteasome β5 subunit overexpression improves proteostasis during aging and extends lifespan in Drosophila melanogaster
    122. TORC 1‐mediated sensing of chaperone activity alters glucose metabolism and extends lifespan
    123. As predicted by hyperfunction theory, rapamycin treatment during development extends lifespan
    124. Astragalus polysaccharide extends lifespan via mitigating endoplasmic reticulum stress in the silkworm, Bombyx mori
    125. Echinacoside, a phenylethanoid glycoside from Cistanche deserticola, extends lifespan of Caenorhabditis elegans and protects from Aβ-induced toxicity
    126. Cocoa improves age-associated health and extends lifespan in C. elegans
    127. IgG3 deficiency extends lifespan and attenuates progression of glomerulonephritis in MRL/lprmice
    128. Over-expression of human clusterin increases stress resistance and extends lifespan in Drosophila melanogaster
    129. Early-stage treatment with Withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral …
    130. S‐adenosyl‐L‐homocysteine extends lifespan through methionine restriction effects
    131. A high-fat jelly diet restores bioenergetic balance and extends lifespan in the presence of motor dysfunction and lumbar spinal cord motor neuron loss in TDP …
    132. A nutritional supplement containing lactoferrin stimulates the immune system, extends lifespan, and reduces amyloid β peptide toxicity in Caenorhabditis elegans
    133. Minocycline treatment increases resistance to oxidative stress and extends lifespan in Drosophila via FOXO
    134. Sonneradon A extends lifespan of Caenorhabditis elegans by Modulating Mitochondrial and IIS Signaling Pathways
    135. Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of …
    136. Concentrated fish oil (Lovaza®) extends lifespan and attenuates kidney disease in lupus-prone short-lived (NZBxNZW) F1 mice
    137. Caloric restriction extends lifespan of mothers at the expense of offspring survival in a predatory mite (Neoseiulus cucumeris)
    138. Inhibition of histone acetyltransferase GCN5 extends lifespan in both yeast and human cell lines
    139. Bark extract of the amazonian tree Endopleura uchi (Humiriaceae) extends lifespan and enhances stress resistance in Caenorhabditis elegans
    140. Experimentally reduced insulin/IGF‐1 signaling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring
    141. Rapamycin treatment during development extends lifespan and healthspan
    142. Jouvence a small nucleolar RNA required in the gut extends lifespan in Drosophila
    143. Activation of autophagy attenuates motor deficits and extends lifespan in a C. elegans model of ALS
    144. Human IGF1 extends lifespan and enhances resistance to Plasmodium falciparum infection in the malaria vector Anopheles stephensi
    145. Translational control of gene expression by eIF2 modulates proteostasis and extends lifespan
    146. Dimethyl sulfide protects against oxidative stress and extends lifespan via a methionine sulfoxide reductase A‐dependent catalytic mechanism
    147. Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function
    148. Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice
    149. Traditional tonifying polyherbal infusion, Jatu-Phala-Tiga, exerts antioxidant activities and extends lifespan of Caenorhabditis elegans
    150. Neuron-specific overexpression of core clock genes improves stress-resistance and extends lifespan of Drosophila melanogaster
    151. Ambient temperature reduction extends lifespan via activating cellular degradation activity in an annual fish (Nothobranchius rachovii)
    152. Hypoxia extends lifespan of Brachionus manjavacas (Rotifera)
    153. Intermittent exposure to fluorescent light extends lifespan of human diploid fibroblasts in culture
    154. Neuronal‐specific proteasome augmentation via Prosβ5 overexpression extends lifespan and reduces age‐related cognitive decline
    155. Ilex paraguariensis extends lifespan and Increases an Ability to Resist Environmental Stresses in Drosophila
    156. FOXM1 delays senescence and extends lifespan
    157. Glycerol extends lifespan of Brachionus manjavacas (Rotifera) and protects against stressors
    158. Inhibition of a eukaryotic initiation factor (eIF2Bδ,/F11A3.2) during adulthood extends lifespan in Caenorhabditis elegans
    159. Crotamiton derivative JM03 extends lifespan and improves oxidative and hypertonic stress resistance in Caenorhabditis elegans via inhibiting OSM-9
    160. Brd2 haploinsufficiency extends lifespan and healthspan in C57B6/J mice
    161. Reduced expression of alpha‐1,2‐mannosidase I extends lifespan in Drosophila melanogaster and Caenorhabditis elegans
    162. Lentinan extends lifespan and increases oxidative stress resistance through DAF-16 and SKN-1 pathways in Caenorhabditis elegans
    163. Hepatic lipase deficiency delays atherosclerosis, myocardial infarction, and cardiac dysfunction and extends lifespan in SR-BI/apolipoprotein E double knockout mice
    164. Mutation of the caspase-3 cleavage site in the astroglial glutamate transporter EAAT2 delays disease progression and extends lifespan in the SOD1-G93A mouse …
    165. A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice
    166. Transition state analogue of MTAP extends lifespan of APCMin/+ mice
    167. Astaxanthin extends lifespan via altered biogenesis of the mitochondrial respiratory chain complex III
    168. Inhibition of GIP signaling extends lifespan without caloric restriction
    169. IL-10 based immunomodulation initiated at birth extends lifespan in a familial mouse model of amyotrophic lateral sclerosis
    170. Mutation of daf‐2 extends lifespan via tissue‐specific effectors that suppress distinct life‐limiting pathologies
    171. Rejuvenation of the disposable soma: repeated injury extends lifespan in an asexual annelid
    172. Reduced neuronal expression of ribose‐5‐phosphate isomerase enhances tolerance to oxidative stress, extends lifespan, and attenuates polyglutamine toxicity in …
    173. Astragaloside IV extends lifespan of Caenorhabditis elegans by Improving Age-Related Functional Declines and Triggering Antioxidant Responses
    174. The collagen-derived compound collagen tripeptide induces collagen expression and extends lifespan via a conserved p38 mitogen-activated protein kinase cascade
    175. Chinese liquor extract attenuates oxidative damage in HepG2 cells and extends lifespan of Caenorhabditis elegans
    176. DhHP-6 extends lifespan of Caenorhabditis elegans by enhancing nuclear translocation and transcriptional activity of DAF-16
    177. A critical review of the evidence that metformin is a putative anti-aging drug that enhances healthspan and extends lifespan
    178. Gemals, a new drug candidate, extends lifespan and improves electromyographic parameters in a rat model of amyotrophic lateral sclerosis
    179. Identification of a sustainable two-plant diet that effectively prevents age-related metabolic syndrome and extends lifespan in aged mice
    180. Liangyi Gao extends lifespan and exerts an antiaging effect in Caenorhabditis elegans by modulating DAF-16/FOXO
    181. Reevaluation of whether a soma–to–germ-line transformation extends lifespan in Caenorhabditis elegans
    182. Loss of NDG‐4 extends lifespan and stress resistance in Caenorhabditis elegans
    183. Autophagy extends lifespan via vacuolar acidification
    184. Reduced expression of frataxin extends the lifespan of Caenorhabditis elegans
    185. Oleuropein Enhances Stress Resistance and extends lifespan via Insulin/IGF-1 and SKN-1/Nrf2 Signaling Pathway in Caenorhabditis elegans
    186. Genetic perturbation of key central metabolic genes extends lifespan in Drosophila and affects response to dietary restriction
    187. Jujube (Ziziphus Jujuba Mill.) fruit feeding extends lifespan and increases tolerance to environmental stresses by regulating aging-associated gene expression in …
    188. A mid-life crisis for aging theory: from yeast to mice, limiting food intake slows aging and extends lifespan. Activators of the sirtuins, enzymes famously linked to this …
    189. Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
    190. Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorhabditis elegans
    191. PAK1-deficiency/down-regulation reduces brood size, activates HSP16. 2 gene and extends lifespan in Caenorhabditis elegans
    192. Syntaxin 4 overexpression ameliorates effects of aging and high-fat diet on glucose control and extends lifespan
    193. Streptococcus thermophilus extends lifespan through activation of DAF-16-mediated antioxidant pathway in Caenorhabditis elegans
    194. The neuroprotector benzothiazepine CGP37157 extends lifespan in C. elegans worms
    195. Enhancing mask activity in dopaminergic neurons extends lifespan in flies
    196. Knockdown expression of eukaryotic initiation factor 5 C-terminal domain containing protein extends lifespan in Drosophila melanogaster
    197. Cur2004-8, a synthetic curcumin derivative, extends lifespan and modulates age-related physiological changes in Caenorhabditis elegans
    198. S-allylmercapto-N-acetylcysteine protects against oxidative stress and extends lifespan in Caenorhabditis elegans
    199. Short-term enhancement of motor neuron synaptic exocytosis during early aging extends lifespan in Caenorhabditis elegans
    200. Loss of miR-83 extends lifespan and affects target gene expression in an age-dependent manner in Caenorhabditis elegans
    201. Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila
    202. A C-terminal truncated mutation of spr-3 gene extends lifespan in Caenorhabditis elegans
    203. Knock-down of odr-3 and ife-2 additively extends lifespan and healthspan in C. elegans
    204. Ethanol extends lifespan of the rotifer Brachionus plicatilis
    205. Increased Akt signaling in the fat body of Anopheles stephensi extends lifespan and increases lifetime fecundity through modulation of insulin-like peptides
    206. Potassium restriction boosts vacuolar acidity and extends lifespan in yeast
    207. A steroid hormone that extends the lifespan of Caenorhabditis elegans
    208. Consumption of a low glycaemic index diet in late life extends lifespan of Balb/c mice with differential effects on DNA damage
    209. 2-SeCD treatment extends lifespan, improves healthspan and enhances resistance to stress in Caenorhabditis elegans
    210. Rapamycin additively extends lifespan in short-and long-lived lines of the nematode Caenorhabditis remanei
    211. Degradation of alpha-synuclein by dendritic cell factor 1 delays neurodegeneration and extends lifespan in Drosophila
    212. Cell-cell metabolite exchange creates a pro-survival metabolic environment that extends lifespan
    213. Enhancing autophagy by redox regulation extends lifespan in Drosophila
    214. Glucose extends lifespan through enhanced intestinal barrier integrity in Drosophila
    215. Rapamycin extends maximal lifespan in cancer-prone mice
    216. Dietary Glycine Supplementation extends lifespan of Genetically Heterogeneous Mice
    217. Increased expression of BubR1 protects against aneuploidy and cancer and extends healthy lifespan
    218. 10-Hydroxy-2-decenoic acid, the major lipid component of royal jelly, extends the lifespan of Caenorhabditis elegans through dietary restriction and target of …
    219. Alpha-ketoglutarate extends Drosophila lifespan by inhibiting mTOR and activating AMPK
    220. Valproic acid extends Caenorhabditis elegans lifespan
    221. Hyperactivation of the proteasome core particle in Caenorhabditis elegans protects against proteotoxic stress and extends lifespan
    222. Osh6 overexpression extends the lifespan of yeast by increasing vacuole fusion
    223. Pyropia haitanensis polysaccharide extends lifespan by inhibiting protein aggregation in Caenorhabditis elegans
    224. Downregulation of EDTP in glial cells suppresses polyglutamine protein aggregates and extends lifespan in Drosophila melanogaster
    225. Enhanced proteasome degradation extends Caenorhabditis elegans lifespan and alleviates aggregation-related pathologies
    226. A genetic model of methionine restriction extends Drosophila health-and lifespan
    227. Systemic delivery of rAAV6-microdystrophin preserves muscle function and extends lifespan in a murine model of severe muscular dystrophy
    228. ENA-A actimineral resource A extends lifespan associated with antioxidant mechanism in SMP30 knockout mice
    229. Overexpression of Fatty-Acid-𝜷-Oxidation-Related Genes extends the lifespan of Drosophila melanogaster
    230. Transition state analogue of MTAP extends lifespan of APCMin/+ mice
    231. Crocus sativus L. protects against SDS‑induced intestinal damage and extends lifespan in Drosophila melanogaster
    232. PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila
    233. Anti-aging effects of Ketanserin; Ketanserin extends lifespan in female drosophila, inhibits cellular senescence and promotes wound healing in-vitro
    234. LanCL1 promotes motor neuron survival and extends the lifespan of amyotrophic lateral sclerosis mice
    235. Lindera obtusiloba extends lifespan of Caenorhabditis elegans
    236. Correction: PGAM5 promotes lasting FoxO activation after developmental mitochondrial stress and extends lifespan in Drosophila
    237. Inhibition of retrotransposition improves health and extends lifespan of SIRT6 knockout mice
    238. Fructose extends lifespan and Reduces Intestinal Fat Deposition in Caenorhabditis elegans
    239. Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexes
    240. Author Correction: IL-10 based immunomodulation initiated at birth extends lifespan in a familial mouse model of amyotrophic lateral sclerosis
    241. Commentary: Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans
    242. Withanolide A extends the lifespan in human EGFR-driven cancerous Caenorhabditis elegans
    243. eIF2B extends lifespan through inhibition of the integrated stress response
    244. Valproic ACID extends lifespan of the Zebrafish Model of CLN2 Disease (Late Infantile Neuronal Ceroid Lipofuscinosis)
    245. Dietary Restriction extends lifespan through Metabolic Regulation of Innate Immunity
    246. Overexpression of protein carboxyl methyltransferase extends lifespan in Drosophila melanogaster
    247. Antioxidant extends lifespan
    248. d-Allulose, a stereoisomer of d-fructose, extends Caenorhabditis elegans lifespan through a dietary restriction mechanism: A new candidate dietary restriction mimetic
    249. Forcing contacts between mitochondria and the endoplasmic reticulum extends lifespan in a Drosophila model of Alzheimer’s disease.
    250. … of rheumatoid arthritis. Nat. Med. (2005) 11:936-943, and BARBER DF, BARTOLOMÉ A, HERNANDEZ C et al.: PI3Kg inhibition blocks glomerulonephritis and extends lifespan in a mouse …
    251. INCREASE IN HSP25 extends lifespan AND IMPROVES RESPONSE TO TAU TOXICITY THROUGH A CELL, NON-AUTONOMOUS MECHANISM
    252. Hepatocyte Transplantation (HTx) extends lifespan, Increases Branched Chain a-Keto Acid Dehydrogenase (BCKDH) Activity, and Improves Neurotransmitter and …
    253. Systemic Administration of Telomerase RNA Reverses Vascular Senescence and extends lifespan in Progeria Mice
    254. ZOLEDRONATE extends lifespan AND HEALTHSPAN IN VIVO
    255. Ophiopogon japonicus herbal tea ameliorates oxidative stress and extends lifespan in caenorhabditis elegans
    256. Lithium extends lifespan and Slows Brain Aging
    257. NEURONAL-SPECIFIC PROTEASOME AUGMENTATION VIA extends lifespan AND REDUCES AGE-RELATED NEURODEGENERATION
    258. Celecoxib extends C. elegans lifespan via inhibition of insulin‐like signaling but not cyclooxygenase‐2 activity
    259. Downregulation of the tyrosine degradation pathway extends Drosophila lifespan
    260. Inhibition of lipid peroxidation during the reproductive period extends the lifespan of Caenorhabditis elegans
    261. REGULATION OF GLUCOSE STORAGE extends lifespan AND PROMOTES HEALTHSPAN
    262. Prohibitin depletion extends lifespan of a TORC2/SGK-1 mutant through autophagy
    263. No evidence that wine drinking extends lifespan
    264. Drinking Chamomile Tea extends lifespan
    265. Use of stable isotopes to examine how dietary restriction extends Drosophila lifespan
    266. Royalactin extends lifespan of C. elegans through EGF signaling
    267. Calorie restriction extends the chronological lifespan of Saccharomyces cerevisiae independently of the Sirtuins
    268. A small molecule norathyriol extends lifespan in association with mitochondrial function in C. elegans
    269. Supplementation with elenocysteine extends lifespan and modulates age-related physiological alterations in C. elegans
    270. Chicoric Acid Promotes Glucose Uptake and extends lifespan
    271. Enzyme role found for aging gene: two labs independently discover mechanism for how Sir2 extends lifespan.(Hot Papers)
    272. Metformin extends C. elegans lifespan through lysosomal pathway
    273. jouvence, a new small nucleolar RNA required in the gut extends lifespan in Drosophila
    274. Long live the Queen-Royalactin extends lifespan of C. elegans through epidermal growth factor (EGF) signaling
    275. β‐Guanidinopropionic acid extends the lifespan of Drosophila melanogaster via an AMP‐activated protein kinase‐dependent increase in autophagy
    276. Korean Red Ginseng Tonic extends lifespan in D. melanogaster
    277. Inhibition of Isw2‐mediated chromatin remodeling by calorie restriction extends lifespan by potentiating stress response
    278. Synergism between soluble guanylate cyclase signaling and neuropeptides extends lifespan in the nematode Caenorh…
    279. Alaskan Lowbush Cranberry extends lifespan in C. elegans
    280. Tissue-specific downregulation of EDTP suppresses polyglutamine protein aggregates and extends lifespan in Drosophila
    281. Fully hydrogenated canola oil extends lifespan in stroke-prone spontaneously hypertensive rats
    282. Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy.
    283. Rapamycin extends murine lifespan but has limited effects on aging
    284. β‐Hydroxy‐β‐methylbutyrate extends lifespan and attenuates age‐dependent loss of flight ability in Drosophila melanogaster (246.2)
    285. Corrigendum to “Autophagy induction extends lifespan and reduces lipids content in response to frataxin silencing in C. elegans”[Exp. Gerontol. 48 (2013) 191–201]
    286. Geranylgeranylacetone Ameliorates Beta-Amyloid Toxicity and extends lifespan via the Heat Shock Response in Caenorhabditis elegans
    287. Reprogrammed M1 macrophages with inhibited STAT3, STAT6 and/or SMAD3 extends lifespan of mice with experimental carcinoma
    288. miR-17 extends mouse lifespan by inhibiting senescence signaling mediated by MKP7
    289. … TREATMENT REGIMENS MITIGATE THE IMPACT OF RAPAMYCIN ON GLUCOSE HOMEOSTASIS AND THE IMMUNE SYSTEM, AND extends lifespan
    290. Dietary restriction extends the lifespan of circadian mutants tim and per
    291. Moderate hypoxia (10 kPa) extends lifespan with adult but not juvenile exposure in the fruitfly, Drosophila melanogaster
    292. 629. Intravenous Delivery of a MTMR2-Encoding AAV9 Vector extends lifespan and Improves Muscle Function in Mice with X-Linked Myotubular Myopathy
    293. 713. IntraCSF Administration of AAV9/MeCP2 extends lifespan of MeCP2-Null Mice While Preventing Toxicity Associated With IV Administration
    294. Enhancing S-adenosyl-methionine catabolism extends Drosophila lifespan
    295. Neoagarotetraose extends the lifespan of Caenorhabditis elegans through AMPK mediated signaling pathways and activation of autophagy
    296. Is Gcn4-induced autophagy the ultimate downstream mechanism by which hormesis extends yeast replicative lifespan?
    297. Nmdmc overexpression extends Drosophila lifespan and reduces levels of mitochondrial reactive oxygen species
    298. Caffeine extends yeast lifespan by targeting TORC1
    299. A salicylic acid derivative extends the lifespan of Caenorhabditis elegans by activating autophagy and the mitochondrial unfolded protein response
    300. A new Schizosaccharomyces pombe chronological lifespan assay reveals that caloric restriction promotes efficient cell cycle exit and extends longevity
    301. Ferulsinaic acid attenuation of advanced glycation end products extends the lifespan of Caenorhabditis elegans
    302. Inhibition of GMP synthesis extends yeast replicative lifespan
    303. CAN1 arginine permease deficiency extends yeast replicative lifespan via translational activation of stress response genes
    304. HUMAN IGF1 extends MOZZIE lifespan
    305. Restoration of energy homeostasis by SIRT6 extends healthy lifespan
    306. Overexpression of malic enzyme in the larval stage extends Drosophila lifespan
    307. Inhibitor GSK690693 extends Drosophila lifespan via reduce AKT signaling pathway
    308. rBTI extends Caenorhabditis elegans lifespan by mimicking calorie restriction
    309. Neuronal expression of a single‐subunit yeast NADH–ubiquinone oxidoreductase (Ndi1) extends Drosophila lifespan
    310. Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan
    311. Isonicotinamide extends yeast chronological lifespan through a mechanism that diminishes nucleotides
    312. Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan
    313. Aiweixin, a Traditional Uyghur Medicinal Formula, extends the lifespan of Caenorhabditis elegans
    314. SIRT1 markedly extends replicative lifespan if the NAD+ salvage pathway is enhanced
    315. Elevated Proteasome Capacity extends Replicative lifespan in Saccharomyces cerevisiae
    316. Caloric restriction or catalase inactivation extends yeast chronological lifespan by inducing H2O2 and superoxide dismutase activity
    317. Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway
    318. Curcumin Acetylsalicylate extends the lifespan of Caenorhabditis elegans
    319. gas1 mutation extends chronological lifespan via Pmk1 and Sty1 MAPKs in Schizosaccharomyces pombe
    320. SKO1 deficiency extends chronological lifespan in Saccharomyces cerevisiae
    321. Gengnianchun extends the lifespan of Caenorhabditis elegans via the insulin/IGF-1 signalling pathway
    322. The Gcn4 transcription factor reduces protein synthesis capacity and extends yeast lifespan
    323. Deficiency of the RNA-binding protein Cth2 extends yeast replicative lifespan by alleviating its repressive effects on mitochondrial function
    324. Reduced expression of C/EBPβ-LIP extends health and lifespan in mice
    325. Post-reproductive inhibition of the autophagic vesicle nucleation complex extends C. elegans lifespan through the neurons
    326. Growth hormone receptor gene disruption in mature-adult mice improves male insulin sensitivity and extends female lifespan
    327. A novel gene, ecl1+, extends the chronological lifespan in fission yeast
    328. Telomere elongation in the gut extends zebrafish lifespan
    329. Low-dose chloroquine treatment extends the lifespan of aged rats
    330. Glucosamine extends the lifespan of Caenorhabditis elegans via autophagy induction
    331. Parishin from Gastrodia elata extends the lifespan of yeast via regulation of Sir2/Uth1/TOR signaling pathway
    332. Acidic Food pH Increases Palatability and Consumption and extends Drosophila lifespan
    333. Dairy Propionibacterium extends the mean lifespan of Caenorhabditis elegans via activation of the innate immune system
    334. D-Allose, a Stereoisomer of D-Glucose, extends the lifespan of Caenorhabditis elegans via Sirtuin and Insulin Signaling D-Allose extends Nematode lifespan via …
    335. Aspirin extends the lifespan of Caenorhabditis elegans via AMPK and DAF-16/FOXO in dietary restriction pathway
    336. Haploinsufficiency of Trp53 dramatically extends the lifespan of Sirt6-deficient mice
    337. Reduced expression of C/EBPb-LIP extends health and lifespan in mice
    338. Korean mistletoe (Viscum album coloratum) extract extends the lifespan of nematodes and fruit flies
    339. Mild Muscle Mitochondrial Fusion Distress extends Drosophila lifespan through an Early and Systemic Metabolome Reorganization
    340. Iron supplementation delays aging and extends cellular lifespan through potentiation of mitochondrial function
    341. Loss of tumor suppressor STAG2 promotes telomere recombination and extends the replicative lifespan of normal human cells
    342. Tectochrysin increases stress resistance and extends the lifespan of Caenorhabditis elegans via FOXO/DAF-16
    343. Sulfur restriction extends fission yeast chronological lifespan through Ecl1 family genes by downregulation of ribosome
    344. Zymolytic Grain Extract (ZGE) Significantly extends the lifespan and Enhances the Environmental Stress Resistance of Caenorhabditis elegans
    345. A mutation that alters the 255th glutamate to lysine in RSKS-1/S6 kinase reliably extends the lifespan of C. elegans
    346. Expression of human HSP27 in yeast extends replicative lifespan and uncovers a hormetic response
    347. Serum from calorie-restricted animals delays senescence and extends the lifespan of normal human fibroblasts in vitro
    348. Gentiopicroside, a secoiridoid glycoside from Gentiana rigescens Franch, extends the lifespan of yeast via inducing mitophagy and antioxidative Stress
    349. Loss of E2F-1 reduces tumorigenesis and extends the lifespan of Rb1 (+/−) mice
    350. Nordihydroguaiaretic Acid extends the lifespan of Drosophila and Mice, Increases Mortality-Related Tumors and Hemorrhagic Diathesis, and Alters …
    351. Honeysuckle extract (Lonicera pallasii L.) exerts antioxidant properties and extends the lifespan and healthspan of Drosophila melanogaster
    352. Lithocholic Acid extends Yeast Chronological lifespan, Drives the Evolution of Longevity Regulation Mechanisms in Ecosystems and Suppresses Mitochondrial …
    353. Inhibition of intestinal absorption of cholesterol by ezetimibe or bile acids by SC-435 alters lipoprotein metabolism and extends the lifespan of SR-BI/apoE double …
    354. The retrotransposon Ty1 extends chronological lifespan in Saccharomyces paradoxus by influencing cellular responses to stress
    Share
    0
    INTERSTELLAR BLEND

    Related posts

    June 1, 2022

    STEM CELL THERAPY


    Read more
    June 1, 2022

    PHYTOCHEMICALS


    Read more
    June 1, 2022

    SMALLPOX


    Read more

    Comments are closed.

    Recent Posts

    • STEM CELL THERAPY
    • PHYTOCHEMICALS
    • SMALLPOX
    • ELLAGIC ACID
    • CYANIDIN
    © 2022 Interstellar Blends | Activate Your Super Powers!. © 2019 Interstellar Blends | Activate Your Super Powers!. All Rights Reserved.

    Mandatory FDA Disclaimer
    Privacy Policy
    Terms and Conditions
    Have Questions?
    Contact Gavin Robert McGowen Here

    Join the following facebook groups to learn more:
    Ultimate Weightloss Challenge , Dry Fasting, Longevity Agents , Interstellar Blend Seven Sages, The Infinitely Postive, THE INTERSTELLAR BLEND CHALLENGE: Fluid Restricted Fasting w/ Superherbs

    Love this Website? Contact David Rodriguez to build you one!