Dysbiosis Clinical applications of urinary organic acids. Part 2. Dysbiosis markers Mechanisms of microbe–host interaction in Crohn's disease: dysbiosis vs. pathobiont selection Dysbiosis and the immune system Administration of probiotic mixture DM# 1 ameliorated 5-fluorouracil–induced intestinal mucositis and dysbiosis in rats Paneth cell defects in Crohn's disease patients promote dysbiosis A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis Dysbiosis of the faecal microbiota in patients with Crohn's disease and their unaffected relatives Current understanding of dysbiosis in disease in human and animal models Defining dysbiosis and its influence on host immunity and disease Dysbiosis of the gut microbiota in disease The severity of nonalcoholic fatty liver disease is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota Antibiotics, pediatric dysbiosis, and disease Proteobacteria: microbial signature of dysbiosis in gut microbiota Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases Mechanisms and consequences of intestinal dysbiosis Cognitive impairment by antibiotic-induced gut dysbiosis: analysis of gut microbiota-brain communication Deviations in human gut microbiota: a novel diagnostic test for determining dysbiosis in patients with IBS or IBD Dysbiosis in inflammatory bowel disease Gut dysbiosis is linked to hypertension Fungal microbiota dysbiosis in IBD Beyond the red complex and into more complexity: the polymicrobial synergy and dysbiosis (PSD) model of periodontal disease etiology Gut microbiota dysbiosis contributes to the development of hypertension Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity Diet-induced dysbiosis of the intestinal microbiota and the effects on immunity and disease Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism The causes of intestinal dysbiosis: a review Microbial dysbiosis in colorectal cancer (CRC) patients Microbiota dysbiosis controls the neuroinflammatory response after stroke High-throughput clone library analysis of the mucosa-associated microbiota reveals dysbiosis and differences between inflamed and non-inflamed regions of … Dysbiosis and Staphylococcus aureus colonization drives inflammation in atopic dermatitis Enteric dysbiosis associated with a mouse model of alcoholic liver disease From gut dysbiosis to altered brain function and mental illness: mechanisms and pathways Fungal dysbiosis: immunity and interactions at mucosal barriers Dysbiosis in the Gut Microbiota of Patients with Multiple Sclerosis, with a Striking Depletion of Species Belonging to Clostridia XIVa and IV Clusters Dysbiosis in inflammatory bowel diseases: the oxygen hypothesis Dysbiosis and its discontents Dysbiosis contributes to arthritis development via activation of autoreactive T cells in the intestine Dysbiosis, inflammation, and response to treatment: a longitudinal study of pediatric subjects with newly diagnosed inflammatory bowel disease Alteration of intestinal dysbiosis by fecal microbiota transplantation does not induce remission in patients with chronic active ulcerative colitis Intestinal dysbiosis in preterm infants preceding necrotizing enterocolitis: a systematic review and meta-analysis Intestinal dysbiosis associated with systemic lupus erythematosus Microbial dysbiosis is associated with human breast cancer Mechanisms of inflammation-driven bacterial dysbiosis in the gut Age-associated microbial dysbiosis promotes intestinal permeability, systemic inflammation, and macrophage dysfunction Dysbiosis gut microbiota associated with inflammation and impaired mucosal immune function in intestine of humans
Genomic instability and cancer Genomic instability and colon cancer Apoptosis and genomic instability Genomic instability induced by ionizing radiation The connection between transcription and genomic instability The role of nuclear architecture in genomic instability and ageing Radiation-induced genomic instability Genomic instability—the engine of tumorigenesis? Genomic instability in laminopathy-based premature aging Chromosomal biomarkers of genomic instability relevant to cancer Genomic instability and radiation Patterns of genomic instability in gastric cancer: clinical implications and perspectives Characterization of sporadic colon cancer by patterns of genomic instability Genomic instability and tumor progression: mechanistic considerations Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins Radiation-induced genomic instability and its implications for radiation carcinogenesis Genomic instability in Ip and human malignancies Genomic instability in Gadd45a-deficient mice The role of DNA breaks in genomic instability and tumorigenesis Genomic instability and bystander effects: a historical perspective Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Heavy metals of relevance to human health induce genomic instability Radiation-induced genomic instability: radiation quality and dose response Radiation-induced genomic instability in haemopoietic cells Radiation-induced DNA damage and delayed induced genomic instability Segmental duplications: an'expanding'role in genomic instability and disease The onset and extent of genomic instability in sporadic colorectal tumor progression The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability DNA damage tumor suppressor genes and genomic instability The impact of a negligent G2/M checkpoint on genomic instability and cancer induction Genomic instability and cancer Breast tumor copy number aberration phenotypes and genomic instability Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 MicroRNAs and genomic instability The role of genomic instability in human carcinogenesis. Genomic instability in mice lacking histone H2AX Genomic instability induced by high and low LET ionizing radiation A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability Progression to cancer in Barrett's esophagus is associated with genomic instability. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability Transient excess of MYC activity can elicit genomic instability and tumorigenesis Hypoxia and defective apoptosis drive genomic instability and tumorigenesis Radiation-induced genomic instability Genomic instability in MycER-activated Rat1A-MycER cells Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX DNA helicases, genomic instability, and human genetic disease Genomic instability and cancer: networks involved in response to DNA damage Mitochondrial dysfunction leads to telomere attrition and genomic instability Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination Genomic instability and tolerance to alkylating agents. Derivation of Human Tumor
Aging, inflammation and the environment Molecular mechanisms of aging-associated inflammation Oxidative stress and vascular inflammation in aging Source of chronic inflammation in aging Exercise, inflammation and aging Para-inflammation in the aging retina Aging and inflammation in two epidemiological worlds Stress, inflammation, and aging Inflammation and the degenerative diseases of aging Inflammation in aging: cause, effect, or both? An update of the oxidation-inflammation theory of aging: the involvement of the immune system in oxi-inflamm-aging Molecular inflammation: underpinnings of aging and age-related diseases Aging, inflammation and cancer The effects of inflammation, aging and oxidative stress on the pathogenesis of diabetes mellitus (type 2 diabetes) Aging and inflammation: etiological culprits of cancer Redefining chronic inflammation in aging and age-related diseases: proposal of the senoinflammation concept Immune aging, dysmetabolism, and inflammation in neurological diseases Aging, inflammation, and HIV infection Role of inflammation in the aging bones Role of redox-regulated transcription factors in inflammation, aging and age-related diseases Retracted: chronic inflammation: accelerator of biological aging Inflammation, aging and hematopoiesis: A complex relationship Protective role of polyphenols against vascular inflammation, aging and cardiovascular disease Inflammation markers in relation to cognition in a healthy aging population Role of neutral sphingomyelinases in aging and inflammation Aging of the immune system: focus on inflammation and vaccination The role of oxidative stress and inflammation in cardiovascular aging Regulation of inflammation as an anti‐aging intervention Angiotensin II revisited: new roles in inflammation, immunology and aging Inflammation, the complement system and the diseases of aging Vascular inflammation in aging Aging-related inflammation in osteoarthritis Exploring the complex relations between inflammation and aging (inflamm-aging): anti-inflamm-aging remodelling of inflamm-aging, from robustness to frailty Molecular inflammation hypothesis of aging based on the anti‐aging mechanism of calorie restriction ELISA and multiplex technologies for cytokine measurement in inflammation and aging research Molecular inflammation as an underlying mechanism of the aging process and age-related diseases Growth hormone, inflammation and aging Chronic inflammation as a determinant of future aging phenotypes Inflammation, aging, and cancer: tumoricidal versus tumorigenesis of immunity: a common denominator mapping chronic diseases Aging, longevity, inflammation, and cancer Myosteatosis and myofibrosis: relationship with aging, inflammation and insulin resistance Inflammation: roles in aging and sarcopenia Inflammation and endothelial dysfunction during aging: role of NF-κB Adipose tissue inflammation in aging Exercise modulates oxidative stress and inflammation in aging and cardiovascular diseases Cognitive dysfunction with aging and the role of inflammation Inflammation and mesenchymal stem cell aging HIV infection, inflammation, immunosenescence, and aging Aging, inflammation, immunity and periodontal disease Oxidative stress, inflammation, and vascular aging in hypertension The inflammation hypothesis of aging: molecular modulation by calorie restriction A role for local inflammation in the formation of drusen in the aging eye Emerging relationships of inflammation, cardiovascular disease and chronic diseases of aging Low-grade systemic inflammation connects aging, metabolic syndrome and cardiovascular disease RAGE signaling in inflammation and arterial aging Evolution of the human lifespan and diseases of aging: roles of infection, inflammation, and nutrition Energy metabolism and inflammation in brain aging and Alzheimer's disease Aging, inflammation, stem cells, and bone healing
Biguanide-associated lactic acidosis: case report and review of the literature Lactic acidosis in biguanide-treated diabetics: a review of 330 cases Biguanides and NIDDM Pharmacophoric features of biguanide derivatives: an electronic and structural analysis Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide Outcome of Acanthamoeba keratitis treated with polyhexamethyl biguanide and propamidine Re-evaluation of a biguanide, metformin: mechanism of action and tolerability Biguanide The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide Metformin: a new oral biguanide New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups Interaction of a polymeric biguanide biocide with phospholipid membranes Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque activity Physical and chemical characterization of poly (hexamethylene biguanide) hydrochloride Comparing two polymeric biguanides: chemical distinction, antiseptic efficacy and cytotoxicity of polyaminopropyl biguanide and polyhexamethylene biguanide Comparison of polyhexamethylene biguanide and chlorhexidine as monotherapy agents in the treatment of Acanthamoeba keratitis Effect of a polyhexamethylene biguanide mouthrinse on bacterial counts and plaque … analysis of zigzag polyhexamethylene biguanide, polyhexamethylene adipamide, polyhexamethylene biguanide gauze and polyhexamethylene biguanide … Polyhexamethylene Biguanide (PHMB): An Addendum to Current Topical Antimicrobials. Biguanide hydrochloride Vanadyl–biguanide complexes as potential synergistic insulin mimics Synergism within polyhexamethylene biguanide biocide formulations Biguanide related compounds in traditional antidiabetic functional foods Biguanide treatment increases the number of insulin-receptor sites on human erythrocytes Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro In vitro and in vivo modulation of alternative splicing by the biguanide metformin Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication … corneal staining associated with the use of balafilcon silicone-hydrogel contact lenses disinfected with a polyaminopropyl biguanide-preserved care regimen Bactericidal effects of polyhexamethylene biguanide against intracellular Staphylococcus aureus EMRSA-15 and USA 300 Cysticidal effect on Acanthamoeba and toxicity on human keratocytes by polyhexamethylene biguanide and chlorhexidine Effects of the biguanide class of oral hypoglycemic agents on mouse embryogenesis Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1 Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents The activation of the biguanide antimalarial proguanil co‐segregates with the mephenytoin oxidation polymorphism‐a panel study. An EPR study of copper (II)-substituted biguanide complexes. Part III Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling Polyhexamethylene biguanide exposure leads to viral aggregation … biologically active molecules with phospholipid membranes: I. Fluorescence depolarization studies on the effect of polymeric biocide bearing biguanide groups in the … Reduction of bacterial burden and pain in chronic wounds using a new polyhexamethylene biguanide antimicrobial foam dressing: clinical trial results Studies on synthetic antimalarial drugs: X.—some biguanide derivatives as new types of antimalarial substances with both therapeutic and causal prophylactic activity Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis Polyhexamethylene biguanide functionalized cationic silver nanoparticles for enhanced antimicrobial activity Biguanide related lactic acidosis: incidence and risk factors. Environmental fate of polyhexamethylene biguanide Analysis of polyhexamethylene biguanide in multipurpose contact lens solutions Cooperativity in the binding of the cationic
Sulfonylureas Sulfonylureas in NIDDM Sulfonylureas. Sulfonylureas Sulfonylureas Why, Which, and How? Sulfonylureas and Sulfonylthioureas. Effects on lipid profile of dipeptidyl peptidase 4 inhibitors, pioglitazone, acarbose, and sulfonylureas: meta-analysis of placebo-controlled trials Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6. 2 mutations State of the art paper Sulfonylureas and their use in clinical practice Increased cancer-related mortality for patients with type 2 diabetes who use sulfonylureas or insulin Risk of mortality and adverse cardiovascular outcomes in type 2 diabetes: a comparison of patients treated with sulfonylureas and metformin Metformin, sulfonylureas, or other antidiabetes drugs and the risk of lactic acidosis or hypoglycemia: a nested case-control analysis Incidence and risk factors for serious hypoglycemia in older persons using insulin or sulfonylureas Effective treatment with oral sulfonylureas in patients with diabetes due to sulfonylurea receptor 1 (SUR1) mutations Individual sulfonylureas and serious hypoglycemia in older people Homeostasis model assessment as a clinical index of insulin resistance in type 2 diabetic patients treated with sulfonylureas. Glucose, Sulfonylureas, and Neurotransmitter Release: Role of ATP-Sensitive K+ Channels Variation in TCF7L2 Influences Therapeutic Response to Sulfonylureas: A GoDARTs Study Rates of hypoglycemia in users of sulfonylureas Incidence of dementia is increased in type 2 diabetes and reduced by the use of sulfonylureas and metformin The pharmacology of sulfonylureas The receptor for antidiabetic sulfonylureas controls the activity of the ATP-modulated K+ channel in insulin-secreting cells. Cardiovascular safety of sulfonylureas: a meta‐analysis of randomized clinical trials Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K (ATP) channels. Is the combination of sulfonylureas and metformin associated with an increased risk of cardiovascular disease or all-cause mortality? A meta-analysis of observational … Mortality risk among sulfonylureas: a systematic review and network meta-analysis Comparison of efficacy, secondary failure rate, and complications of sulfonylureas Effects on the incidence of cardiovascular events of the addition of pioglitazone versus sulfonylureas in patients with type 2 diabetes inadequately controlled with … The place of sulfonylureas in the therapy for type 2 diabetes mellitus Mechanisms of the glycaemic effects of sulfonylureas Sulfonylureas and the risks of cardiovascular events and death: a methodological meta-regression analysis of the observational studies Loss‐of‐function CYP2C9 variants improve therapeutic response to sulfonylureas in type 2 diabetes: a Go‐DARTS study Extrapancreatic effects of sulfonylureas—a comparison between glimepiride and conventional sulfonylureas Clinical observation on trigonella foenum-graecum L. total saponins in combination with sulfonylureas in the treatment of type 2 diabetes mellitus Sulfonylureas as second line drugs in type 2 diabetes and the risk of cardiovascular and hypoglycaemic events: population based cohort study Efficacy and safety of once-weekly semaglutide versus once-daily insulin glargine as add-on to metformin (with or without sulfonylureas) in insulin-naive patients with … Sulfonylureas and ischaemic preconditioning; a double-blind, placebo-controlled evaluation of glimepiride and glibenclamide PKC-dependent stimulation of exocytosis by sulfonylureas in pancreatic β cells Tissue-specific effects of sulfonylureas: lessons from studies of cloned KATP channels Metformin and sulfonylureas in relation to cancer risk in type II diabetes patients: a meta-analysis using primary data of published studies Sulfonylureas: a
Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight Synthesis of novel indenoquinoxaline derivatives as potent α-glucosidase inhibitors Studies on α-glucosidase inhibitors development: magic molecules for the treatment of carbohydrate mediated diseases Newer insights into the drug delivery approaches of α-glucosidase inhibitors Novel inhibitors with sulfamethazine backbone: synthesis and biological study of multi-target cholinesterases and α-glucosidase inhibitors Synthesis of andrographolide derivatives: a new family of α-glucosidase inhibitors Rapid screening and identification of α‐glucosidase inhibitors from mulberry leaves using enzyme‐immobilized magnetic beads coupled with HPLC/MS and NMR Interaction of antidiabetic α‐glucosidase inhibitors and gut bacteria α‐glucosidase Synthetic α-glucosidase inhibitors as promising anti-diabetic agents: Recent developments and future challenges α-Glucosidase inhibitors prevent diet-induced increases in intestinal sugar transport in diabetic mice Discovery of novel α-glucosidase inhibitors based on the virtual screening with the homology-modeled protein structure Oxindole based oxadiazole hybrid analogs: Novel α-glucosidase inhibitors Polyoxomolybdates as α-glucosidase inhibitors: Kinetic and molecular modeling studies α-glucosidase inhibitors as host-directed antiviral agents with potential for the treatment of COVID-19 Synthesis and molecular docking studies of potent α-glucosidase inhibitors based on biscoumarin skeleton First Identification of α-Glucosidase Inhibitors from Okra (Abelmoschus Esculentus) Seeds Synthesis and bioevaluation of glycosyl ureas as α-glucosidase inhibitors and their effect on mycobacterium α-Glucosidase inhibitors reduce dengue virus production by affecting the initial steps of virion morphogenesis in the endoplasmic reticulum Mini-Special Issue paper Management of diabetic patients with hypoglycemic agents α-Glucosidase inhibitors and their use in clinical practice Antioxidants and α-glucosidase inhibitors from Ipomoea batatas leaves identified by bioassay-guided approach and structure-activity relationships Triazoloquinazolines as a new class of potent α-glucosidase inhibitors: in vitro evaluation and docking study Thielavins A, J and K: α-Glucosidase inhibitors from MEXU 27095, an endophytic fungus from Hintonia latiflora New novel α–glucosidase inhibitors produced by microbial conversion A Determination of Potential α-Glucosidase Inhibitors from Azuki Beans (Vigna angularis) α-Glucosidase Inhibitors from a Xylaria feejeensis Associated with Hintonia latiflora Acylated flavonol monorhamnosides, α-glucosidase inhibitors, from Machilus philippinensis α-Glucosidase Inhibitors from Vauquelinia corymbosa α-Glucosidase Inhibitors from Clove (Syzgium aromaticum) Discovery of novel oxindole derivatives as potent α-glucosidase inhibitors Fruit by-products: The potential natural sources of antioxidants and α-glucosidase inhibitors Microbial α-glucosidase inhibitors: chemistry, biochemistry, and therapeutic potential α-Glucosidase inhibitors from Commelina communis Five-membered iminocyclitol α-glucosidase inhibitors: synthetic, biological screening and in silico studies α-Glucosidase inhibitors from brown rice bound phenolics extracts (BRBPE): Identification and mechanism New α-glucosidase inhibitors from the resins of Boswellia species with structure–glucosidase activity and molecular docking studies Synthesis, in vitro evaluation and molecular docking studies of novel triazine-triazole derivatives as potential α-glucosidase inhibitors Triterpenes as α-glucosidase inhibitors from Fagus hayatae Effect of two α-glucosidase inhibitors, voglibose and acarbose, on postprandial hyperglycemia correlates with subjective abdominal symptoms Probing 2-acetylbenzofuran hydrazones and their metal complexes as α-glucosidase inhibitors Comparative study of dietary flavonoids with different structures as α-glucosidase inhibitors and insulin sensitizers Hetarylcoumarins: synthesis and biological evaluation as potent α-glucosidase inhibitors Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC …
Comparative review of dipeptidyl peptidase‐4 inhibitors and sulphonylureas Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences Dipeptidyl peptidase‐4 (DPP‐4) inhibitors for type 2 diabetes mellitus Safety of dipeptidyl peptidase 4 inhibitors: a perspective review Pharmacology, physiology, and mechanisms of action of dipeptidyl peptidase-4 inhibitors Dipeptidyl peptidase‐4 inhibitors in the treatment of type 2 diabetes: a comparative review Whey proteins as source of dipeptidyl dipeptidase IV (dipeptidyl peptidase-4) inhibitors Mechanism of action of inhibitors of dipeptidyl-peptidase-4 (DPP-4) Dipeptidyl peptidase 4 inhibitors and their potential immune modulatory functions Comparative clinical pharmacokinetics of dipeptidyl peptidase-4 inhibitors The nonglycemic actions of dipeptidyl peptidase-4 inhibitors Dipeptidyl peptidase-4 (DPP-4) inhibitors in the management of diabetes Safety of dipeptidyl peptidase-4 inhibitors: a meta-analysis of randomized clinical trials Dipeptidyl peptidase 4 inhibitors in the treatment of type 2 diabetes mellitus A review of dipeptidyl peptidase‐4 inhibitors. Hot topics from randomized controlled trials Dipeptidyl peptidase-4 inhibitors and bone fractures: a meta-analysis of randomized clinical trials Safety of dipeptidyl peptidase-4 inhibitors for treating type 2 diabetes Dipeptidyl peptidase-4 inhibitors: Novel mechanism of actions Tolerability of dipeptidyl peptidase-4 inhibitors: a review Dipeptidyl peptidase-4 inhibitors for treatment of type 2 diabetes mellitus in the clinical setting: systematic review and meta-analysis Emerging dipeptidyl peptidase-4 inhibitors for the treatment of diabetes Dipeptidyl peptidase-4 inhibitors: 3 years of experience Efficacy and safety of dipeptidyl peptidase-4 inhibitors in type 2 diabetes: meta-analysis Dipeptidyl peptidase‐4 inhibitors for the treatment of type 2 diabetes mellitus Dipeptidyl peptidase-4 inhibitors and heart failure: a meta-analysis of randomized clinical trials Predictors of response to dipeptidyl peptidase‐4 inhibitors: evidence from randomized clinical trials Emerging role of dipeptidyl peptidase-4 inhibitors in the management of type 2 diabetes Dipeptidyl peptidase-4 inhibitors for the treatment of type 2 diabetes: comparison, efficacy and safety Dipeptidyl peptidase‐4 inhibitors and cardiovascular risk: a meta‐analysis of randomized clinical trials Overview of the gliptin class (dipeptidyl peptidase-4 inhibitors) in clinical practice Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors Meta-analysis of effect of dipeptidyl peptidase-4 inhibitors on cardiovascular risk in type 2 diabetes mellitus Dipeptidyl peptidase‐4 inhibitors for the treatment of type 2 diabetes: focus on sitagliptin Cardiovascular effects of dipeptidyl peptidase-4 inhibitors: from risk factors to clinical outcomes Dipeptidyl peptidase‐4 inhibitors and cardiovascular outcomes: meta‐analysis of randomized clinical trials with 55,141 participants Cardiovascular effects of dipeptidyl peptidase-4 inhibitors in diabetic patients: a meta-analysis Dipeptidyl‐peptidase‐4 inhibitors and pancreatic cancer: a cohort study Exposure to dipeptidyl‐peptidase‐4 inhibitors and COVID‐19 among people with type 2 diabetes: a case‐control study Differences in the glucose-lowering efficacy of dipeptidyl peptidase-4 inhibitors between Asians and non-Asians: a systematic review and meta-analysis Role of dipeptidyl peptidase 4 inhibitors in antidiabetic treatment Effects on lipid profile of dipeptidyl peptidase 4 inhibitors, pioglitazone, acarbose, and sulfonylureas: meta-analysis of placebo-controlled trials Clinical implications of cardiovascular preventing pleiotropic effects of dipeptidyl peptidase-4 inhibitors Longer term safety of dipeptidyl peptidase‐4 inhibitors in patients with type 2 diabetes mellitus: systematic review and meta‐analysis Dipeptidyl peptidase-4 inhibitors cause bullous pemphigoid in diabetic patients: report of two cases The incretin
Nutrient-sensing mechanisms and pathways Nutrient sensing and signaling: NPKS Nutrient-sensing mechanisms across evolution Perspective: hexosamines and nutrient sensing Nutrient sensing and inflammation in metabolic diseases Structure of the nutrient-sensing hub GATOR2 Nutrient sensing and metabolic decisions Nutrient sensing, metabolism, and cell growth control Nutrient sensing in plant meristems Hexosamines as mediators of nutrient sensing and regulation in diabetes TOR signaling and nutrient sensing Nutrient sensing and signaling in the yeast Saccharomyces cerevisiae Regulation of tissue growth through nutrient sensing The unfolded protein response in nutrient sensing and differentiation Neuronal regulation of homeostasis by nutrient sensing The metabolic impact of small intestinal nutrient sensing Nutrient sensing in the gut: new roads to therapeutics? Nutrient sensing and the oxidative stress response Hypothalamic nutrient sensing in the control of energy homeostasis Minireview: nutrient sensing and the regulation of insulin action and energy balance The TOR kinases link nutrient sensing to cell growth The “Real-Time” revolution for in situ soil nutrient sensing Regulation of reproduction and longevity by nutrient-sensing pathways Nutrient sensing and TOR signaling in yeast and mammals Role of placental nutrient sensing in developmental programming Nutrient sensing and signalling in plants: potassium and phosphorus Nutrient sensing in cancer The eukaryotic plasma membrane as a nutrient-sensing device Nutrient sensing, autophagy, and diabetic nephropathy Nutrient-sensing pathways and metabolic regulation in stem cells Nutrient sensing and signalling by the gut Nutrient-sensing nuclear receptors coordinate autophagy A nutrient-sensing pathway regulates leptin gene expression in muscle and fat With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging Nutrient sensing and the circadian clock AMPK and TOR: the yin and yang of cellular nutrient sensing and growth control Molecular disruption of hypothalamic nutrient sensing induces obesity Gut microbiota, nutrient sensing and energy balance Integration of nutrient sensing in fish hypothalamus Nutrient sensing: another chemosensitivity of the olfactory system Nutrient sensing, signal transduction and immune responses The role of placental nutrient sensing in maternal-fetal resource allocation Role of nutrient-sensing signals in the pathogenesis of diabetic nephropathy Control of YAP/TAZ activity by metabolic and nutrient-sensing pathways Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals p62 is a key regulator of nutrient sensing in the mTORC1 pathway γδ T cells regulate the intestinal response to nutrient sensing The emerging role of mTORC1 signaling in placental nutrient-sensing mTOR couples cellular nutrient sensing to organismal metabolic homeostasis Nutrient sensing modulates malaria parasite virulence eIF4GI links nutrient sensing by mTOR to cell proliferation and inhibition of autophagy Autophagy-nutrient sensing pathways in diabetic complications Nutrient sensing: what can we learn from different tastes about the nutrient contents in today's foods? Nutrient-sensing mechanisms in the gut as therapeutic targets for diabetes Nutrient sensing systems in fish: impact on food intake regulation and energy homeostasis Dietary restriction in C. elegans: from rate-of-living effects to nutrient sensing pathways Lactobacillus plantarum promotes Drosophila systemic growth by modulating hormonal signals through TOR-dependent nutrient sensing Modeling metabolic homeostasis and nutrient sensing in Drosophila: implications for aging and metabolic diseases Nutrient sensing, growth and senescence
Thiazolidinediones Nonhypoglycemic effects of thiazolidinediones Thiazolidinediones Thiazolidinediones: an update The mode of action of thiazolidinediones Metabolic and additional vascular effects of thiazolidinediones Thiazolidinediones in the treatment of insulin resistance and type II diabetes How safe is the use of thiazolidinediones in clinical practice? Unraveling the mechanism of action of thiazolidinediones Insulin resistance and its treatment by thiazolidinediones. A meta-analysis comparing the effect of thiazolidinediones on cardiovascular risk factors Use of thiazolidinediones and fracture risk Thiazolidinediones as anti-cancer agents Thiazolidinediones in type 2 diabetes mellitus: current clinical evidence Effect of thiazolidinediones on body weight in patients with diabetes mellitus Thiazolidinediones and fractures in men and women Thiazolidinediones: a new class of antidiabetic drugs Thiazolidinediones and liver toxicity. Protection of the kidney by thiazolidinediones: an assessment from bench to bedside Long-term use of thiazolidinediones and fractures in type 2 diabetes: a meta-analysis Thiazolidinediones: a 2010 perspective Thiazolidinediones: effects on insulin resistance and the cardiovascular system Thiazolidinediones and cardiovascular outcomes in older patients with diabetes Pleiotropic effects of thiazolidinediones The adipocyte in insulin resistance: key molecules and the impact of the thiazolidinediones Hepatotoxicity with thiazolidinediones: is it a class effect? Hepatotoxicity of the thiazolidinediones Thiazolidinediones-mechanisms of action Thiazolidinediones and blood lipids in type 2 diabetes Thiazolidinediones and heart failure: a teleo-analysis Thiazolidinediones: metabolic actions in vitro Mechanisms of early insulin-sensitizing effects of thiazolidinediones in type 2 diabetes The effect of thiazolidinediones on plasma adiponectin levels in normal, obese, and type 2 diabetic subjects Thiazolidinediones and inflammation Mechanisms by which thiazolidinediones enhance insulin action Comparative cardiovascular effects of thiazolidinediones: systematic review and meta-analysis of observational studies The safety of thiazolidinediones Considerations for management of fluid dynamic issues associated with thiazolidinediones Effect of thiazolidinediones on albuminuria and proteinuria in diabetes: a meta-analysis Thiazolidinediones, metformin, and outcomes in older patients with diabetes and heart failure: an observational study Hepatotoxicity of thiazolidinediones Thiazolidinediones and the risk of edema: a meta-analysis Thiazolidinediones: a comparative review of approved uses Thiazolidinediones and the risk of lung, prostate, and colon cancer in patients with diabetes Thiazolidinediones block fatty acid release by inducing glyceroneogenesis in fat cells Thiazolidinediones, peripheral edema, and type 2 diabetes: incidence, pathophysiology, and clinical implications Thiazolidinediones improve β-cell function in type 2 diabetic patients The effect of thiazolidinediones on BMD and osteoporosis Thiazolidinediones for the treatment of type 2 diabetes Visfatin is an adipokine, but it is not regulated by thiazolidinediones Pharmacokinetic interactions with thiazolidinediones Thiazolidinediones and fractures: evidence from translating research into action for diabetes Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones Thiazolidinediones block tumor necrosis factor-alpha-induced inhibition of insulin signaling. Thiazolidinediones as anti‐inflammatory and anti‐atherogenic agents Thiazolidinediones: the case for early use PPARγ-independent antitumor effects of thiazolidinediones The role of thiazolidinediones in non-alcoholic steatohepatitis–a systematic review and meta analysis New drugs for the treatment of diabetes mellitus: part I: Thiazolidinediones and their evolving cardiovascular implications Thiazolidinediones–some recent developments Thiazolidinediones, insulin resistance and obesity: finding a balance Pleiotropic effects of thiazolidinediones: taking a look beyond antidiabetic activity Thiazolidinediones can
Antilipolytic effect of insulin in isolated fat cells of the rat The Antilipolytic action of insulin in obese subjects with resistance to its glucoregulatory action Effect of cell size on lipolysis and Antilipolytic action of insulin in human fat cells Antilipolytic action of insulin on fat cells Systemic resistance to the Antilipolytic effect of insulin in black and white women with visceral obesity Various phosphodiesterase subtypes mediate the in vivo Antilipolytic effect of insulin on adipose tissue and skeletal muscle in man Resveratrol, a naturally occurring diphenolic compound, affects lipogenesis, lipolysis and the Antilipolytic action of insulin in isolated rat adipocytes Antilipolytic action of insulin: role of cAMP phosphodiesterase activation The Antilipolytic effect of insulin in human adipose tissue in obesity, diabetes mellitus, hyperinsulinemia, and starvation Adipose tissue lipolysis revisited (again!): lactate involvement in insulin Antilipolytic action Insensitivity of large rat adipocytes to the Antilipolytic effects of insulin Evidence for the key role of the adipocyte cGMP-inhibited cAMP phosphodiesterase in the Antilipolytic action of insulin Pro12Ala Polymorphism in the Peroxisome Proliferator–Activated Receptor-γ2 Gene Is Associated With Increased Antilipolytic insulin Sensitivity insulin receptor down-regulation and impaired Antilipolytic action of insulin in diabetic patients after pancreas/kidney transplantation Antilipolytic actions of vanadate and insulin in rat adipocytes mediated by distinctly different mechanisms A longitudinal study of the Antilipolytic effect of insulin in women following bariatric surgery Antilipolytic effects of insulin and adenylate cyclase inhibitors on isolated human fat cells. Effect of the Antilipolytic nicotinic acid analogue acipimox on whole-body and skeletal muscle glucose metabolism in patients with non-insulin-dependent diabetes … Regulation of insulin-stimulated glucose transport in the isolated rat adipocyte. cAMP-independent effects of lipolytic and Antilipolytic agents. Role of phosphodiesterase III in the Antilipolytic effect of insulin in vivo Influence of obesity on the Antilipolytic effect of insulin in isolated human fat cells obtained before and after glucose ingestion. insulin-mimetic compound hexaquis (benzylammonium) decavanadate is Antilipolytic in human fat cells Glucocorticoids antagonize tumor necrosis factor-α-stimulated lipolysis and resistance to the Antilipolytic effect of insulin in human adipocytes Evidence for marked sensitivity to the Antilipolytic action of insulin in obese maturity-onset diabetics The Antilipolytic effects of insulin and epidermal growth factor in rat adipocytes are mediated by different mechanisms Molecular mechanisms involved in the Antilipolytic action of insulin: phosphorylation and activation of a particulate adipocyte cAMP phosphodiesterase Antilipolytic actions of insulin on basal and hormone-induced lipolysis in rat adipocytes Overactivation of the endocannabinoid system alters the Antilipolytic action of insulin in mouse adipose tissue Comparative studies of the Antilipolytic effect of insulin and adenosine in the perifused isolated fat cell The Antilipolytic effect of insulin in human adipocytes requires activation of the phosphodiesterase Lowering of triglycerides by gemfibrozil affects neither the glucoregulatory nor Antilipolytic effect of insulin in type 2 (non-insulin-dependent) diabetic patients Glucose stimulation of the Antilipolytic effect of insulin in humans Resistance to the Antilipolytic effect of insulin in adipocytes of African-American compared to Caucasian postmenopausal women PKB inhibition prevents the stimulatory effect of insulin on glucose transport and protein translocation but