… (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary … … a supplement containing conjugated linoleic acid on dairy performance, milk fatty acid composition, and adipose tissue reactivity to lipolytic challenge in mid … … analogs of lysolecithin and their use in a continuous spectrophotometric assay for lysophospholipases, a method with potential applicability to other lipolytic enzymes … and reduction of fat stores on the antilipolytic alpha 2-adrenoceptor in hamster adipocytes: comparison with adenosine and beta-adrenergic lipolytic … … and Yarrowia lipolytica strains in dried fermented sausage manufacture. Part 1: Evaluation of their effects on microbial evolution, lipolytic and proteolytic patterns … breast adenocarcinoma (MCF-7) cells proliferation in co-culture with human adipocytes in three dimensional collagen gel matrix: norepinephrine as a lipolytic … … diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to … … during postprandial lipemia parallels the response of triglyceride-rich lipoproteins in type 2 diabetes: no relationship between apoA-V and postheparin plasma lipolytic … … high‐density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and type 2 diabetes mellitus: role of lipolytic enzymes, lecithin: cholesterol … … human breast adenocarcinoma [MCF-7] cells proliferation in co-culture with human adipocytes in three dimensional collagen gel matrix: norepinephrine as a lipolytic … … HYPERSENSITIVE RESPONSE OF BEAN INOCULATED WITH PSEUDOMONAS SYRINGAE PV. PHASEOLICOLA RACE 1 (PHASEOLUS VULGARIS, lipolytic … … in biological materials. II. The measurement of adenosine 3', 5'-monophosphate in tissues and the role of the cyclic nucleotide in the lipolytic response of fat to … … IN THE EARLY PERIODS AFTER IONIZING RADIATION AND THE EFFECT OF WHOLE-BODY ALPHAIRRADIATION ON lipolytic ENZYME INDUCTION BY … … of 1-substituted 6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinolines: inhibition of 3H-dopamine accumulation by rat brain slices and lipolytic activity with isolated mouse … … of a versatile cassette for directional genome walking using cassette ligation-mediated PCR and its application in the cloning of complete lipolytic genes from Bacillus … … of an axenic fungal isolate of aspergillus sp.(mbl-1511) and its subsequent improvement for enhanced extracellular lipolytic potential through monoculture … … of Corticotropin. III. The Synthesis of L-Histidyl-L-phenylalanyl-L-arginyl-L-tryptophan, the Smallest Peptide Exhibiting the Melanocyte-stimulating and the lipolytic … … of hypertriglyceridemia by two diets rich either in unsaturated fatty acids or in carbohydrates: effects on lipoprotein subclasses, lipolytic enzymes, lipid transfer proteins … … of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic … … of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3 … … of sodium taurodeoxycholate, CaCl2 and albumin on the action of pancreatic lipase on droplets of trioleoylglycerol and the release of lipolytic products into aqueous … … overview of Tityus cisandinus scorpion venom: Transcriptome and

Speculating about PYRAZINES The PYRAZINES. Synthesis of imidazo [1, 2-a] annulated pyridines, PYRAZINES and pyrimidines by a novel three-component condensation Recent advances in development of imidazo [1, 2-a] PYRAZINES: synthesis, reactivity and their biological applications Microwave-accelerated three-component condensation reaction on clay: solvent-free synthesis of imidazo [1, 2-a] annulated pyridines, PYRAZINES and pyrimidines Structure–activity relationships of furazano [3, 4-b] PYRAZINES as mitochondrial uncouplers Direct Synthesis of Chiral 1,2,3,4-Tetrahydropyrrolo[1,2-a]PYRAZINES via a Catalytic Asymmetric Intramolecular Aza-Friedel–Crafts Reaction One-step synthesis of dialkynyl-1, 2-diones and their conversion to fused PYRAZINES bearing enediyne units Discovery of 8-Amino-imidazo[1,5-a]PYRAZINES as Reversible BTK Inhibitors for the Treatment of Rheumatoid Arthritis Structure-Based Drug Design of Novel Potent and Selective Tetrahydropyrazolo[1,5-a]PYRAZINES as ATR Inhibitors Synthesis of Tetrahydropyrrolo/indolo [1, 2-a] PYRAZINES by Enantioselective Hydrogenation of Heterocyclic Imines Piperazinylimidazo [1, 2-a] PYRAZINES with selective affinity for in vitro. alpha.-adrenergic receptor subtypes Identification of 2-amino-5-aryl-PYRAZINES as inhibitors of human lactate dehydrogenase Cascade synthesis of indolizines and pyrrolo [1, 2-a] PYRAZINES from 2-formyl-1-propargylpyrroles Novel thieno-[3, 4-b]-PYRAZINES cored dendrimers with carbazole dendrons: design, synthesis, and application in solution-processed red organic light-emitting diodes Thieno[3,4-b]PYRAZINES:  Synthesis, Structure, and Reactivity Discovery of Imidazo[1,2-a]PYRAZINES and Pyrazolo[1,5-c]pyrimidines as TARP γ-8 Selective AMPAR Negative Modulators 2,3-Diphenylthieno[3,4-b]PYRAZINES as Hole-Transporting Materials for Stable, High-Performance Perovskite Solar Cells PYRAZINES in foods Pyrido[4,3-e][1,2,4]triazolo[4,3-a]PYRAZINES as Selective, Brain Penetrant Phosphodiesterase 2 (PDE2) Inhibitors Brönsted acid hydrotrope combined catalyst for environmentally benign synthesis of quinoxalines and pyrido [2, 3-b] PYRAZINES in aqueous medium PYRAZINES: occurrence, formation and biodegradation Control strategies of PYRAZINES generation from Maillard reaction General microwave-assisted protocols for the expedient synthesis of quinoxalines and heterocyclic PYRAZINES Combretastatin A-4 inspired novel 2-aryl-3-arylamino-imidazo-pyridines/PYRAZINES as tubulin polymerization inhibitors, antimitotic and anticancer agents Parallel synthesis of 3-aminoimidazo [1, 2-a] pyridines and PYRAZINES by a new three-component condensation Assembly of 1,2,3,4-Tetrahydropyrrolo[1,2-a]PYRAZINES via the Domino Reaction of 2-Imidazolines and Terminal Electron-Deficient Alkynes Synthesis, biological evaluation and molecular modeling study of 2-amino-3, 5-disubstituted-PYRAZINES as Aurora kinases inhibitors Imidazo [1, 2-a] pyrimidines and imidazo [1, 2-a] PYRAZINES: the role of nitrogen position in inotropic activity Synthesis and evaluation of imidazo [1, 5-a] PYRAZINES as corticotropin releasing hormone receptor ligands Characterization of PYRAZINES in some Chinese liquors and their approximate concentrations PYRAZINES: Synthesis and industrial application of these valuable flavor and fragrance compounds The biological roles of PYRAZINES: evidence for a warning odour function Influence of free amino acids, oligopeptides, and polypeptides on the formation of PYRAZINES in Maillard model systems Preparation of quinoxalines, dihydroPYRAZINES, PYRAZINES and piperazines using tandem oxidation processes Advances in the directed metallation of azines and diazines (pyridines, pyrimidines, PYRAZINES, pyridazines, quinolines, benzodiazines and carbolines). Part 1 … … Modeling of New Pyrrolo[1,2-a]quinoxalines, Bispyrrolo[1,2-a]quinoxalines, Bispyrido[3,2-e]pyrrolo[1,2-a]PYRAZINES, and Bispyrrolo[1,2-a]thieno[3,2-e]PYRAZINES Preparation of Pyrido-(2, 3)-PYRAZINES, Pyrido-(3, 4)-PYRAZINES and Imidazo-(b)-pyridines 2-and 3-substituted imidazo [1, 2-a] PYRAZINES as inhibitors of bacterial type IV secretion Design and evaluation of 3, 6-di (hetero) aryl imidazo [1, 2-a] PYRAZINES as inhibitors of checkpoint and other kinases Synthesis of 2, 3-disubstituted PYRAZINES and quinoxalines by Heck cross-coupling reactions of 2, 3-dichloropyrazine and 2, 3-dichloroquinoxaline. Influence of the … … of azines and

The biology of PGC-1α and its therapeutic potential PGC-1α: a key regulator of energy metabolism PGC-1α-mediated adaptations in skeletal muscle PGC-1α and PGC-1β regulate mitochondrial density in neurons Bioenergetic analysis of peroxisome proliferator-activated receptor γ coactivators 1α and 1β (PGC-1α and PGC-1β) in muscle cells Multiple environmental and genetic factors influence skeletal muscle PGC-1α and PGC-1β gene expression in twins … PGC-1α) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-α and-γ: identification of novel leucine-rich interaction motif within PGC … Role of PGC‐1α signaling in skeletal muscle health and disease Lipin 1 is an inducible amplifier of the hepatic PGC-1α/PPARα regulatory pathway PGC-1α: turbocharging mitochondria Impaired PGC-1α function in muscle in Huntington's disease PGC-1α, a new therapeutic target in Huntington's disease? PGC-1α in aging and anti-aging interventions PGC-1α regulation by exercise training and its influences on muscle function and insulin sensitivity Peroxisome proliferator-activated receptor-γ coactivator 1α (PGC-1α): transcriptional coactivator and metabolic regulator PGC-1α supports glutamine metabolism in breast cancer FGF15/19 regulates hepatic glucose metabolism by inhibiting the CREB-PGC-1α pathway Transcriptional coactivators PGC-1α and PGC-lβ control overlapping programs required for perinatal maturation of the heart Transcriptional control of mitochondrial biogenesis: the central role of PGC-1α … transcription of the peroxisome proliferator-activated receptor-γ co-activator-1α (PGC-1α) gene in skeletal muscle through the PGC-1α autoregulatory loop and … Activation of nuclear receptor coactivator PGC-1α by arginine methylation Regulation of peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) and mitochondrial function by MEF2 and HDAC5 Nutrient control of glucose homeostasis through a complex of PGC-1α and SIRT1 PGC-1α, mitochondrial dysfunction, and Huntington's disease Metabolic adaptations through the PGC-1α and SIRT1 pathways A fundamental system of cellular energy homeostasis regulated by PGC-1α PGC-1α regulates the mitochondrial antioxidant defense system in vascular endothelial cells Sirtuin 3, a new target of PGC-1α, plays an important role in the suppression of ROS and mitochondrial biogenesis SUMOylation attenuates the function of PGC-1α A role for the transcriptional coactivator PGC-1α in muscle refueling Development of insulin resistance in mice lacking PGC-1α in adipose tissues The estrogen-related receptor α (ERRα) functions in PPARγ coactivator 1α (PGC-1α)-induced mitochondrial biogenesis Regulation of PGC-1α, a nodal regulator of mitochondrial biogenesis Insulin-regulated hepatic gluconeogenesis through FOXO1–PGC-1α interaction Regulation of PPARγ coactivator 1α (PGC-1α) signaling by an estrogen-related receptor α (ERRα) ligand PARIS (ZNF746) repression of PGC-1α contributes to neurodegeneration in Parkinson's disease Endothelial PGC-1α mediates vascular dysfunction in diabetes IRF4 is a key thermogenic transcriptional partner of PGC-1α PGC-1α regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy Fibroblast growth factor 21 regulates energy metabolism by activating the AMPK–SIRT1–PGC-1α pathway PGC-1α expression decreases in the Alzheimer disease brain as a function of dementia The many roles of PGC-1α in muscle—recent developments The role of PGC-1α in the pathogenesis of neurodegenerative disorders The role of PGC-1α on mitochondrial function and apoptotic susceptibility in muscle Metformin induces PGC‐1α expression and selectively affects hepatic PGC‐1α functions PGC-1α is coupled to HIF-1α-dependent gene expression by increasing mitochondrial oxygen consumption in skeletal muscle cells Re-evaluating the FOXO1–PGC-1α connection PGC-1α promotes recovery after

Anti-ovarian cancer potential of phytocompound and extract from South African medicinal plants and their role in the development of chemotherapeutic agents Effect of a combination of extract from several plants on Cell‐mediated and humoral immunity of patients with advanced ovarian cancer Aqueous extract of herba Scutellaria barbatae, a Chinese herb used for ovarian cancer, induces apoptosis of ovarian cancer cell lines The inhibitory effect of ginger extract on ovarian cancer cell line; application of systems biology … , characterization, cytotoxicity, antioxidant, and anti-human ovarian cancer activities of Curcumae kwangsiensis leaf aqueous extract green-synthesized gold … Antitumor activities of Rauwolfia vomitoria extract and potentiation of carboplatin effects against ovarian cancer Effects of Agarum clathratum extract on cell death and calcium ion levels of ovarian cancer cell Huaier aqueous extract inhibits ovarian cancer cell motility via the AKT/GSK3β/β-catenin pathway Synergistic effects of green tea extract and paclitaxel in the induction of mitochondrial apoptosis in ovarian cancer cell lines Evaluation of characteristics of CD44+ CD117+ ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional … The fractionated Toona sinensis leaf extract induces apoptosis of human ovarian cancer cells and inhibits tumor growth in a murine xenograft model The induction of apoptosis in human melanoma, breast and ovarian cancer cell lines using an essential oil extract from the conifer Tetraclinis articulata. Emblica officinalis extract Induces Autophagy and Inhibits Human ovarian cancer Cell Proliferation, Angiogenesis, Growth of Mouse Xenograft Tumors The plant extract of Pao pereira potentiates carboplatin effects against ovarian cancer Anti-human ovarian cancer and cytotoxicity effects of nickel nanoparticles green-synthesized by Alhagi maurorum leaf aqueous extract Efficient biogenesis of Cu2O nanoparticles using extract of Camellia sinensis leaf: Evaluation of catalytic, cytotoxicity, antioxidant, and anti-human ovarian cancer … Characterizing the efficacy of fermented wheat germ extract against ovarian cancer and defining the genomic basis of its activity Anti-proliferative and anti-apoptotic effects of grape seed extract on chemo-resistant OVCAR-3 ovarian cancer cells Kaempferia parviflora extract inhibits TNF-α-induced release of MCP-1 in ovarian cancer cells through the suppression of NF-κB signaling Investigation of anti-human ovarian cancer effects of decorated Au nanoparticles on Thymbra spicata extract modified Fe3O4 nanoparticles Antiangiogenesis efficacy of ethanol extract from Amomum tsaoko in ovarian cancer through inducing ER stress to suppress p-STAT3/NF-kB/IL-6 and VEGF … Bitter Melon (Momordica charantia) extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in ovarian cancer Cells Through Targeting AMPK … … -mediated synthesis of CuO nanoparticles using aqueous leaf extract of Artemisia deserti and their anticancer effects on A2780-CP cisplatin-resistant ovarian cancer … Solanum incanum extract downregulates aldehyde dehydrogenase 1-mediated stemness and inhibits tumor formation in ovarian cancer cells … extract from Baiye No.1 Tea (Camellia sinensis) Flowers Induced S Phase Cell Cycle Arrest and Apoptosis via AKT-MDM2-p53 Signaling Pathway in ovarian cancer … Aqueous extract of Paris polyphylla (AEPP) Inhibits ovarian cancer via Suppression of Peroxisome Proliferator-Activated Receptor-Gamma Coactivator (PGC) … Overcoming cisplatin resistance by targeting the MTDH-PTEN interaction in ovarian cancer with sera derived from rats exposed to Guizhi Fuling wan extract

Anti-cancer effect of Annona Muricata Linn Leaves Crude extract (AMCE) on breast cancer cell line … ) extract Inhibits breast cancer Cell Proliferation by Modulating Cell Cycle Regulatory Genes and Promotes ApoptosisBitter Melon extract Inhibits breast cancer Cell … Anti-cancer properties of diethylether extract of wood from sukun (Artocarpus altilis) in human breast cancer (T47D) cells Effects of salvia officinalis extract on the breast cancer cell line Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF‐7 human breast cancer cell Eugenia jambolana Lam. Berry extract Inhibits Growth and Induces Apoptosis of Human breast cancer but Not Non-Tumorigenic breast Cells Huaier aqueous extract inhibits proliferation of breast cancer cells by inducing apoptosis A phase I/II trial of a polysaccharide extract from Grifola frondosa (Maitake mushroom) in breast cancer patients: immunological effects Cytotoxic activity of Piper cubeba extract in breast cancer cell lines Anticancer activities of an anthocyanin-rich extract from black rice against breast cancer cells in vitro and in vivo Apoptosis and necrosis of human breast cancer cells by an aqueous extract of garden cress (Lepidium sativum) seeds Chemical composition of Solanum nigrum linn extract and induction of autophagy by leaf water extract and its major flavonoids in AU565 breast cancer cells Anticancer activity of litchi fruit pericarp extract against human breast cancer in vitro and in vivo Hydroxytyrosol rich extract from olive leaves modulates cell cycle progression in MCF-7 human breast cancer cells Isopropanolic black cohosh extract and recurrence-free survival after breast cancer The Anti-cancer Activities of Vernonia amygdalina extract in Human breast cancer Cell Lines Are Mediated through Caspase-Dependent and p53 … Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in MDA-MB-231 and MCF-7 breast cancer cells Cytotoxic activity of physodic acid and acetone extract from Hypogymnia physodes against breast cancer cell lines Selective growth inhibition of human breast cancer cells by graviola fruit extract in vitro and in vivo involving downregulation of EGFR expression Antioxidant and apoptotic effects of an aqueous extract of Urtica dioica on the MCF-7 human breast cancer cell line Pomegranate fruit extract impairs invasion and motility in human breast cancer extract from Astragalus membranaceus inhibit breast cancer cells proliferation via PI3K/AKT/mTOR signaling pathway Bitter melon extract inhibits breast cancer growth in preclinical model by inducing autophagic cell death Benefit–risk profile of black cohosh (isopropanolic Cimicifuga racemosa extract) with and without St John's wort in breast cancer patients Antiproliferatory effects of crab shell extract on breast cancer cell line (MCF7) Anti-tumor potential of ethanol extract of Curcuma phaeocaulis Valeton against breast cancer cells Curcumin- and natural extract-loaded nanofibres for potential treatment of lung and breast cancer: in vitro efficacy evaluation … effects of Mangifera indica L. kernel extract on human breast cancer (MCF-7 and MDA-MB-231 cell lines) and bioactive constituents in the crude extract Cytotoxic activity of biosynthesized gold nanoparticles with an extract of the red seaweed Corallina officinalis on the MCF-7 human breast cancer cell line Anticancer and Anti-Inflammatory Properties of Ganoderma lucidum extract Effects on Melanoma and Triple-Negative breast cancer