Saponins, classification and occurrence in the plant kingdom Biological activities and distribution of plant saponins Saponins and plant defence—a soap story A mechanism for the hypocholesterolaemic activity of saponins Chromatographic determination of plant saponins Chromatographic determination of plant saponins—an update (2002–2005) Saponins from edible legumes: chemistry, processing, and health benefits Saponins from Allium minutiflorum with antifungal activity Mechanism of antiviral activity of triterpenoid saponins Saponins in pulses and their health promoting activities: A review Saponins versus plant fungal pathogens Antimicrobial activity of saponins from Medicago sp.: structure‐activity relationship Investigations of the mechanism of membrane activity of selected triterpenoid saponins Antimicrobial activity of saponins from Acacia auriculiformis Effect of saponins on the growth and activity of rhizosphere bacteria Effects of saponins on lipid metabolism: A review of potential health benefits in the treatment of obesity In vitro antifungal activity of triterpenoid saponins Evaluation of the antimicrobial activity of saponins extract of Sorghum bicolor L. Moench The impact of saponins or saponin-containing plant materials on ruminant production A Review Novel advances with plant saponins as natural insecticides to control pest insects In vitro determination of the spermicidal activity of plant saponins Plant-derived saponins: a review of their surfactant properties and applications Characterization and antimutagenic activity of soybean saponins Separation and characterization of saponins with adjuvant activity from Quillaja saponaria Molina cortex. Structure-activity relationships of haemolytic saponins Anti-tumor activity of the crude saponins obtained from asparagus Chemical and Biological Activity of Triterpene Saponins from Medicago Species Exploration of the correlation between the structure, hemolytic activity, and cytotoxicity of steroid saponins Cytotoxic activity of some triterpenoid saponins Role of saponins in plant defense against specialist herbivores Plant triterpenoid saponins: biosynthesis, in vitro production, and pharmacological relevance Anti-inflammatory activity of unusual lupane saponins from Bupleurum fruticescens Steroidal saponins from Asparagus officinalis and their cytotoxic activity Saponins with biological and pharmacological activity Saponins of the ivy plant, Hedera helix, and their leishmanicidic activity In vivo anti-inflammatory activity of saponins from Bupleurum rotundifolium Five New Steroidal Saponins from Solanum chrysotrichum Leaves and Their Antimycotic Activity Structure and hemolytic activity relationships of triterpenoid saponins and sapogenins Commercial utilization of plant-derived saponins: an overview of medicinal, pharmaceutical, and industrial applications Structural analogues of diosgenyl saponins: synthesis and anticancer activity Production of plant bioactive triterpenoid saponins: elicitation strategies and target genes to improve yields Soybean saponins. Fate of ingested soybean saponins and the physiological aspect of their hemolytic activity Challenges associated with elucidating the mechanisms of the hypocholesterolaemic activity of saponins Anthelmintic activity of steroidal saponins from Paris polyphylla Open-chain steroidal glycosides, a diverse class of plant saponins Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro A review of ultrasound-assisted extraction for plant bioactive compounds: Phenolics, flavonoids, thymols, saponins and proteins Antitumor activity of Pulsatilla koreana saponins and their structure–activity relationship Flavonoids and saponins in plant rhizospheres: roles, dynamics, and the potential for agriculture Control of insect pests in crop plants and stored food grains using plant saponins: A review Production of plant bioactive triterpenoid

Garlic as an anti‐fatigue agent Anti-fatigue-fracture hydrogels Glutamine as an anti-fatigue amino acid in sports nutrition Anti-fatigue effect of traditional Chinese medicines: A review Antioxidant and anti-fatigue constituents of okra Anti‐stress and anti‐fatigue effect of fermented rice bran Anti-fatigue activity of the water-soluble polysaccharides isolated from Panax ginseng CA Meyer The anti-fatigue effect of 20 (R)-ginsenoside Rg3 in mice by intranasally administration Anti-fatigue effects of proteins isolated from Panax quinquefolium Study on effect of jellyfish collagen hydrolysate on anti-fatigue and anti-oxidation Anti‐Fatigue and Highly Conductive Thermocells for Continuous Electricity Generation An anti‐fatigue design strategy for 3D ribbon‐shaped flexible electronics Anti-fatigue properties of tartary buckwheat extracts in mice Anti-Fatigue Activity of Extracts of Stem Bark from Acanthopanax senticosus Bioactivity-guided fractionation for anti-fatigue property of Acanthopanax senticosus Anti-fatigue effects of salidroside in mice Purification and anti-fatigue activity of flavonoids from corn silk Stretchable hydrogels with low hysteresis and anti-fatigue fracture based on polyprotein cross-linkers Effects of macamides on endurance capacity and anti-fatigue property in prolonged swimming mice Anti-fatigue activity of polysaccharides from the fruits of four Tibetan plateau indigenous medicinal plants Anti-fatigue activity of a Lachnum polysaccharide and its carboxymethylated derivative in mice Anti-fatigue activity of polysaccharides extract from Radix Rehmanniae Preparata A practical model for efficient anti-fatigue design and selection of metallic materials: I. Model building and fatigue strength prediction Anti-fatigue effect of Amarkand on endurance exercise capacity in rats Anti‐fatigue effect of quercetin on enhancing muscle function and antioxidant capacity Anti-fatigue activity of a novel polysaccharide conjugates from Ziyang green tea Anti-fatigue activities of polysaccharides extracted from Hericium erinaceus Anti-fatigue effects of dietary nucleotides in mice Anti-fatigue effects of 20 (S)-protopanaxadiol and 20 (S)-protopanaxatriol in mice In vitro antioxidant activity and in vivo anti-fatigue effect of loach (Misgurnus anguillicaudatus) peptides prepared by papain digestion A verification of the assumption of anti-fatigue design Human-tissue-inspired anti-fatigue-fracture hydrogel for a sensitive wide-range human–machine interface Anti-fatigue effect of anwulignan via the NRF2 and PGC-1α signaling pathway in mice Anti-fatigue effect of Myelophil in a chronic forced exercise mouse model Scavenging and anti-fatigue activity of fermented defatted soybean peptides Effects of oat β-glucan on endurance exercise and its anti-fatigue properties in trained rats Anti-stress and anti-fatigue effects of fermented rice bran A practical model for efficient anti-fatigue design and selection of metallic materials: II. Parameter analysis and fatigue strength improvement Anti-fatigue effects of active ingredients from traditional Chinese medicine: a review Anti-fatigue activity of polysaccharide fractions from Lepidium meyenii Walp.(maca) Anti-fatigue mats, low back pain, and electromyography: An interventional study Purification, characterization and anti-fatigue activity of polysaccharide fractions from okra (Abelmoschus esculentus (L.) Moench) Structural characterization and anti-fatigue activity of polysaccharides from the roots of Morinda officinalis Corrosion fatigue behavior and anti-fatigue mechanisms of an additively manufactured biodegradable zinc-magnesium gyroid scaffold Synthesis, stability and anti-fatigue activity of selenium nanoparticles stabilized by Lycium barbarum polysaccharides Recent Advances in Panax ginseng CA Meyer as a Herb for Anti-Fatigue: An Effects and Mechanisms Review Anti-fatigue performance in SSVEP-based visual acuity assessment: A comparison of six stimulus paradigms Anti-fatigue

Genomic instability and cancer Genomic instability and colon cancer Apoptosis and genomic instability Genomic instability induced by ionizing radiation The connection between transcription and genomic instability The role of nuclear architecture in genomic instability and ageing Radiation-induced genomic instability Genomic instability—the engine of tumorigenesis? Genomic instability in laminopathy-based premature aging Chromosomal biomarkers of genomic instability relevant to cancer Genomic instability and radiation Patterns of genomic instability in gastric cancer: clinical implications and perspectives Characterization of sporadic colon cancer by patterns of genomic instability Genomic instability and tumor progression: mechanistic considerations Genomic instability in colorectal cancer: relationship to clinicopathological variables and family history Mechanisms of genomic instability in human cancer: insights from studies with human papillomavirus oncoproteins Radiation-induced genomic instability and its implications for radiation carcinogenesis Genomic instability in Ip and human malignancies Genomic instability in Gadd45a-deficient mice The role of DNA breaks in genomic instability and tumorigenesis Genomic instability and bystander effects: a historical perspective Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions Heavy metals of relevance to human health induce genomic instability Radiation-induced genomic instability: radiation quality and dose response Radiation-induced genomic instability in haemopoietic cells Radiation-induced DNA damage and delayed induced genomic instability Segmental duplications: an'expanding'role in genomic instability and disease The onset and extent of genomic instability in sporadic colorectal tumor progression The presence of p53 mutations in human osteosarcomas correlates with high levels of genomic instability DNA damage tumor suppressor genes and genomic instability The impact of a negligent G2/M checkpoint on genomic instability and cancer induction Genomic instability and cancer Breast tumor copy number aberration phenotypes and genomic instability Genomic instability and aging-like phenotype in the absence of mammalian SIRT6 MicroRNAs and genomic instability The role of genomic instability in human carcinogenesis. Genomic instability in mice lacking histone H2AX Genomic instability induced by high and low LET ionizing radiation A role for mitochondrial dysfunction in perpetuating radiation-induced genomic instability Progression to cancer in Barrett's esophagus is associated with genomic instability. Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation Inactivation of the SR protein splicing factor ASF/SF2 results in genomic instability Transient excess of MYC activity can elicit genomic instability and tumorigenesis Hypoxia and defective apoptosis drive genomic instability and tumorigenesis Radiation-induced genomic instability Genomic instability in MycER-activated Rat1A-MycER cells Suppression of genomic instability by SLX5 and SLX8 in Saccharomyces cerevisiae Small polydispersed circular DNA (spcDNA) in human cells: association with genomic instability Increased ionizing radiation sensitivity and genomic instability in the absence of histone H2AX DNA helicases, genomic instability, and human genetic disease Genomic instability and cancer: networks involved in response to DNA damage Mitochondrial dysfunction leads to telomere attrition and genomic instability Genomic instability is an early event during the progression pathway of ulcerative-colitis-related neoplasia Radiation-induced genomic instability: a paradigm-breaking phenomenon and its relevance to environmentally induced cancer Human SHPRH suppresses genomic instability through proliferating cell nuclear antigen polyubiquitination Genomic instability and tolerance to alkylating agents. Derivation of Human Tumor

Biguanide-associated lactic acidosis: case report and review of the literature Lactic acidosis in biguanide-treated diabetics: a review of 330 cases Biguanides and NIDDM Pharmacophoric features of biguanide derivatives: an electronic and structural analysis Treatment of Acanthamoeba keratitis with polyhexamethylene biguanide Outcome of Acanthamoeba keratitis treated with polyhexamethyl biguanide and propamidine Re-evaluation of a biguanide, metformin: mechanism of action and tolerability Biguanide The response of Escherichia coli to exposure to the biocide polyhexamethylene biguanide Metformin: a new oral biguanide New polymeric biocides: synthesis and antibacterial activities of polycations with pendant biguanide groups Interaction of a polymeric biguanide biocide with phospholipid membranes Structural requirements of guanide, biguanide, and bisbiguanide agents for antiplaque activity Physical and chemical characterization of poly (hexamethylene biguanide) hydrochloride Comparing two polymeric biguanides: chemical distinction, antiseptic efficacy and cytotoxicity of polyaminopropyl biguanide and polyhexamethylene biguanide Comparison of polyhexamethylene biguanide and chlorhexidine as monotherapy agents in the treatment of Acanthamoeba keratitis Effect of a polyhexamethylene biguanide mouthrinse on bacterial counts and plaque … analysis of zigzag polyhexamethylene biguanide, polyhexamethylene adipamide, polyhexamethylene biguanide gauze and polyhexamethylene biguanide … Polyhexamethylene Biguanide (PHMB): An Addendum to Current Topical Antimicrobials. Biguanide hydrochloride Vanadyl–biguanide complexes as potential synergistic insulin mimics Synergism within polyhexamethylene biguanide biocide formulations Biguanide related compounds in traditional antidiabetic functional foods Biguanide treatment increases the number of insulin-receptor sites on human erythrocytes Biguanide-induced mitochondrial dysfunction yields increased lactate production and cytotoxicity of aerobically-poised HepG2 cells and human hepatocytes in vitro In vitro and in vivo modulation of alternative splicing by the biguanide metformin Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication … corneal staining associated with the use of balafilcon silicone-hydrogel contact lenses disinfected with a polyaminopropyl biguanide-preserved care regimen Bactericidal effects of polyhexamethylene biguanide against intracellular Staphylococcus aureus EMRSA-15 and USA 300 Cysticidal effect on Acanthamoeba and toxicity on human keratocytes by polyhexamethylene biguanide and chlorhexidine Effects of the biguanide class of oral hypoglycemic agents on mouse embryogenesis Polybiguanides, particularly polyethylene hexamethylene biguanide, have activity against human immunodeficiency virus type 1 Antidiabetic and antimalarial biguanide drugs are metal-interactive antiproteolytic agents The activation of the biguanide antimalarial proguanil co‐segregates with the mephenytoin oxidation polymorphism‐a panel study. An EPR study of copper (II)-substituted biguanide complexes. Part III Biguanide metformin acts on tau phosphorylation via mTOR/protein phosphatase 2A (PP2A) signaling Polyhexamethylene biguanide exposure leads to viral aggregation … biologically active molecules with phospholipid membranes: I. Fluorescence depolarization studies on the effect of polymeric biocide bearing biguanide groups in the … Reduction of bacterial burden and pain in chronic wounds using a new polyhexamethylene biguanide antimicrobial foam dressing: clinical trial results Studies on synthetic antimalarial drugs: X.—some biguanide derivatives as new types of antimalarial substances with both therapeutic and causal prophylactic activity Miltefosine and polyhexamethylene biguanide: a new drug combination for the treatment of Acanthamoeba keratitis Polyhexamethylene biguanide functionalized cationic silver nanoparticles for enhanced antimicrobial activity Biguanide related lactic acidosis: incidence and risk factors. Environmental fate of polyhexamethylene biguanide Analysis of polyhexamethylene biguanide in multipurpose contact lens solutions Cooperativity in the binding of the cationic

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