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    SENESCENT CELLS, SASP & SENOLYTICS
    January 14, 2020
    Acorus Gramineu
    January 15, 2020

    Andrographis Paniculata

    1. Hepatoprotective activity of Andrographolide from Andrographis paniculata against carbontetrachloride.
    2. Andrographolide protects rat hepatocytes against paracetamol-induced damage
    3. In vitro and in vivo anti-inflammatory effects of Andrographolide.
    4. Hepatoprotective activity of Andrographolide against galactosamine & paracetamol intoxication in rats.
    5. A phase I trial of Andrographolide in HIV positive patients and normal volunteers
    6. Andrographolide, a potential cancer therapeutic agent isolated from Andrographis paniculata
    7. Antihyperglycemic effect of Andrographolide in streptozotocin-induced diabetic rats
    8. Choleretic Effect of Andrographolide in Rats and Guinea Pigs1
    9. Synthesis and structure–activity relationships of Andrographolide analogues as novel cytotoxic agents
    10. Antiangiogenic activity of Andrographis paniculata extract and Andrographolide
    11. Inhibitory effect of Andrographolide from Andrographis paniculata on PAF-induced platelet aggregation
    12. Semisynthesis and in vitro anticancer activities of Andrographolide analogues
    13. Pharmacological aspects of Andrographis paniculata on health and its major diterpenoid constituent Andrographolide
    14. Andrographolide prevents oxygen radical production by human neutrophils: possible mechanism (s) involved in its anti‐inflammatory effect
    15. In vitro α-glucosidase and α-amylase enzyme inhibitory effects of Andrographis paniculata extract and Andrographolide
    16. Andrographolide attenuates inflammation by inhibition of NF-κB activation through covalent modification of reduced cysteine 62 of p50
    17. Solid–liquid extraction of Andrographolide from plants—experimental study, kinetic reaction and model
    18. Andrographolide and its analogues: versatile bioactive molecules for combating inflammation and cancer
    19. Andrographolide interferes with T cell activation and reduces experimental autoimmune encephalomyelitis in the mouse
    20. Andrographolide protects against LPS-induced acute lung injury by inactivation of NF-κB
    21. Hepatoprotective effect of Andrographolide against hexachlorocyclohexane-induced oxidative injury
    22. A novel antiinflammatory role for Andrographolide in asthma via inhibition of the nuclear factor-κB pathway
    23. Targeting of Liposomal Andrographolide to L.donovani-Infected Macrophages in Vivo
    24. Mechanisms of suppression of inducible nitric oxide synthase (iNOS) expression in RAW 264.7 cells by Andrographolide
    25. Synthesis and evaluation of antibacterial activities of Andrographolide analogues
    26. Andrographolide interferes with binding of nuclear factor‐κB to DNA in HL‐60‐derived neutrophilic cells
    27. Standardization of the Indian crude drug Kalmegh by high pressure liquid chromatographic determination of Andrographolide
    28. * Semisynthesis and cytotoxic activities of Andrographolide analogues
    29. Andrographolide derivatives inhibit guanine nucleotide exchange and abrogate oncogenic Ras function
    30. Suppression of rat neutrophil reactive oxygen species production and adhesion by the diterpenoid lactone Andrographolide
    31. Six new Andrographolide metabolites in rats
    32. Critical role of pro-apoptotic Bcl-2 family members in Andrographolide-induced apoptosis in human cancer cells
    33. Pharmacokinetic and oral bioavailability of Andrographolide from Andrographis paniculata fixed combination Kan Jang in rats and human
    34. Hypoglycemic and beta cell protective effects of Andrographolide analogue for diabetes treatment
    35. Inhibition of cell-cycle progression in human colorectal carcinoma Lovo cells by Andrographolide
    36. Andrographolide: a new plant-derived antineoplastic entity on horizon
    37. Four new Andrographolide metabolites in rats
    38. A rapid method for isolation of Andrographolide from Andrographis paniculata Nees (Kalmegh)
    39. Experimental and clinical pharmacology of Andrographis paniculata and its major bioactive phytoconstituent Andrographolide
    40. Andrographolide up-regulates cellular-reduced glutathione level and protects cardiomyocytes against hypoxia/reoxygenation injury
    41. Neuroprotective effects of Andrographolide in a rat model of permanent cerebral ischaemia
    42. Andrographolide acts through inhibition of ERK1/2 and Akt phosphorylation to suppress chemotactic migration
    43. Synthesis of Andrographolide derivatives and their TNF-α and IL-6 expression inhibitory activities
    44. A new BIS-Andrographolide Ether from Andrographis paniculata Nees and evaluation of anti-HIV activity
    45. Activity of Andrographolide and its derivatives against influenza virus in vivo and in vitro
    46. Analgesic, antipyretic, anti-inflammatory and toxic effects of Andrographolide derivatives in experimental animals
    47. Protective activity of Andrographolide and arabinogalactan proteins from Andrographis paniculata Nees. against ethanol-induced toxicity in mice
    48. Andrographolide isolated from Andrographis paniculata induces cell cycle arrest and mitochondrial-mediated apoptosis in human leukemic HL-60 cells
    49. Heat-accelerated degradation of solid-state Andrographolide
    50. Activation of Cytotoxic T Lymphocyte Responses and Attenuation of Tumor Growth in vivo by Andrographis paniculata Extract and Andrographolide
    51. Synthesis of Andrographolide derivatives: a new family of α-glucosidase inhibitors
    52. Aspects of the male reproductive toxicity/male antifertility property of Andrographolide in albino rats: effect on the testis and the cauda epididymidal spermatozoa
    53. Antioxidant, antioedema and analgesic activities of Andrographis paniculata extracts and their active constituent Andrographolide
    54. Andrographolide nanoparticles in leishmaniasis: characterization and in vitro evaluations
    55. Andrographolide reduces inflammation-mediated dopaminergic neurodegeneration in mesencephalic neuron-glia cultures by inhibiting microglial activation
    56. DRF 3188 a novel semi-synthetic analog of Andrographolide: cellular response to MCF 7 breast cancer cells
    57. Andrographolide suppresses endothelial cell apoptosis via activation of phosphatidyl inositol-3-kinase/Akt pathway
    58. Studies on the novel α-glucosidase inhibitory activity and structure–activity relationships for Andrographolide analogues
    59. Andrographolide and kalmegh (Andrographis paniculata) extract: in vivo and in vitro effect on hepatic lipid peroxidation.
    60. Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation
    61. Andrographolide inhibits NF-κB activation and attenuates neointimal hyperplasia in arterial restenosis
    62. On the diterpenoids of Andrographis paniculata: X-ray crystallographic analysis of Andrographolide and structure determination of new minor diterpenoids
    63. Andrographolide inhibits IFN-γ and IL-2 cytokine production and protects against cell apoptosis
    64. Separation of Andrographolide and neoAndrographolide from the leaves of Andrographis paniculata using high-speed counter-current chromatography
    65. Andrographolide: Further transformations and stereochemical evidence; the structure of isoAndrographolide
    66. Improved bioavailability of orally administered Andrographolide from pH-sensitive nanoparticles
    67. Andrographolide, the Active Constituent of Andrographis Paniculata Nees. A Preliminary Communication
    68. A stereoselective synthesis of racemic Andrographolide lactone
    69. Inhibition of the Epstein–Barr virus lytic cycle by Andrographolide
    70. Anti-tumor activities of Andrographolide, a diterpene from Andrographis paniculata, by inducing apoptosis and inhibiting VEGF level
    71. Antidiabetic and antihiperlipidemic effect of Andrographis paniculata (Burm. f.) Nees and Andrographolide in high-fructose-fat-fed rats
    72. New substituted C-19-Andrographolide analogues with potent cytotoxic activities
    73. Andrographolide suppresses the expression of inducible nitric oxide synthase in macrophage and restores the vasoconstriction in rat aorta treated with …
    74. Four new Andrographolide metabolites in human urine
    75. Andrographolide protects against cigarette smoke‐induced oxidative lung injury via augmentation of Nrf2 activity
    76. Andrographolide induces cell cycle arrest at G2/M phase and cell death in HepG2 cells via alteration of reactive oxygen species
    77. Inhibition of the JAK-STAT3 pathway by Andrographolide enhances chemosensitivity of cancer cells to doxorubicin
    78. Andrographolide, an herbal medicine, inhibits interleukin-6 expression and suppresses prostate cancer cell growth
    79. Apoptosis inducing effect of Andrographolide on TF-47 human breast cancer cell line
    80. Inhibitory effects of Andrographolide on migration and invasion in human non-small cell lung cancer A549 cells via down-regulation of PI3K/Akt signaling pathway
    81. Identification of a rare sulfonic acid metabolite of Andrographolide in rats
    82. Entrapment of Andrographolide in cross-linked aliginate pellets: II. physicochemical characterization to study the pelletization of Andrographolide
    83. The natural products parthenolide and Andrographolide exhibit anti-cancer stem cell activity in multiple myeloma
    84. Andrographolide suppresses RANKL‐induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo
    85. Natural products in combinatorial chemistry: an Andrographolide-based library
    86. Immunomodulatory activity of Andrographolide on macrophage activation and specific antibody response
    87. Andrographolide inhibits oral squamous cell carcinogenesis through NF-κB inactivation
    88. Differential inhibition of rat and human hepatic cytochrome P450 by Andrographis paniculata extract and Andrographolide
    89. Andrographolide inhibits the tumour necrosis factor‐α‐induced upregulation of ICAM‐1 expression and endothelial‐monocyte adhesion
    90. Mitochondrial-mediated apoptosis in lymphoma cells by the diterpenoid lactone Andrographolide, the active component of Andrographis paniculata
    91. Andrographolide acts as an anti-inflammatory agent in LPS-stimulated RAW264. 7 macrophages by inhibiting STAT3-mediated suppression of the NF-κB pathway
    92. Andrographolide enhances 5-fluorouracil-induced apoptosis via caspase-8-dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma …
    93. Synthesis, cytotoxicity, and structure–activity relationship (SAR) studies of Andrographolide analogues as anti-cancer agent
    94. Production of Andrographolide from adventitious root cultures of Andrographis paniculata
    95. Morphological and biochemical changes of Andrographolide-induced cell death in human prostatic adenocarcinoma PC-3 cells
    96. Benzylidene derivatives of Andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis
    97. Andrographolide sensitizes cisplatin-induced apoptosis via suppression of autophagosome-lysosome fusion in human cancer cells
    98. Study of the supramolecular inclusion of β-cyclodextrin with Andrographolide
    99. Design, synthesis and antibacterial activity of novel Andrographolide derivatives
    100. Strong synergistic induction of CYP1A1 expression by Andrographolide plus typical CYP1A inducers in mouse hepatocytes
    101. HPLC determination of Andrographolide in rat whole blood: study on the pharmacokinetics of Andrographolide incorporated in liposomes and tablets
    102. Computational study on the molecular inclusion of Andrographolide by cyclodextrin
    103. Andrographolide and analogues in cancer prevention
    104. Development of Andrographolide molecularly imprinted polymer for solid-phase extraction
    105. Inhibition of NF-κB expression and allergen-induced airway inflammation in a mouse allergic asthma model by Andrographolide
    106. Supercritical carbon dioxide extraction of Andrographolide from Andrographis paniculata: effect of the solvent flow rate, pressure, and temperature
    107. Andrographolide CONTENT IN MADHYA PRADESH, INDIA
    108. Biosynthesis of Andrographolide in Andrographis paniculata
    109. Andrographolide inhibits human hepatoma-derived Hep3B cell growth through the activation of c-Jun N-terminal kinase
    110. Andrographolide inhibits the production of TNF-α and interleukin-12 in lipopolysaccharide-stimulated macrophages: role of mitogen-activated protein kinases
    111. Andrographolide inhibits the adhesion of gastric cancer cells to endothelial cells by blocking E-selectin expression
    112. Andrographolide: a novel antimalarial diterpene lactone compound from Andrographis paniculata and its interaction with curcumin and artesunate
    113. In Vivo and In Vitro Effects of Kalmegh (Andrographis paniculata) Extract and Andrographolide on Hapatic Microsomal Drug Metabolizing Enzymes1
    114. Isolation and identification of seven glucuronide conjugates of Andrographolide in human urine
    115. Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells
    116. Andrographolide enhances nuclear factor-κB subunit p65 Ser536 dephosphorylation through activation of protein phosphatase 2A in vascular smooth muscle cells
    117. Poor oral bioavailability of a promising anticancer agent Andrographolide is due to extensive metabolism and efflux by P‐glycoprotein
    118. Activity of antibacterial, antiviral, anti-inflammatory in compounds Andrographolide salt
    119. Inhibition of TNF-α-induced inflammation by Andrographolide via down-regulation of the PI3K/Akt signaling pathway
    120. AP-1/IRF-3 targeted anti-inflammatory activity of Andrographolide isolated from Andrographis paniculata
    121. Enhancing bioavailability and hepatoprotective activity of Andrographolide from Andrographis paniculata, a well‐known medicinal food, through its herbosome
    122. The human bitter taste receptor hTAS2R50 is activated by the two natural bitter terpenoids Andrographolide and amarogentin
    123. Andrographolide induces autophagic cell death in human liver cancer cells through cyclophilin D-mediated mitochondrial permeability transition pore
    124. Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice
    125. Evaluation of molecular pharmaceutical and in‐vivo properties of spray‐dried isolated Andrographolide—PVP
    126. Mediation of β-endorphin in Andrographolide-induced plasma glucose-lowering action in type I diabetes-like animals
    127. ANALYSIS OF Andrographolide COMPOUNDS Ⅰ. ION PAIR HIGH PERFORMANCE LIQUID CHROMATOGRAPHIC ANALYSIS OF Andrographolide …
    128. Andrographolide: an X-ray crystallographic analysis
    129. Andrographolide ameliorates diabetic retinopathy by inhibiting retinal angiogenesis and inflammation
    130. Andrographolide reduces IL-2 production in T-cells by interfering with NFAT and MAPK activation
    131. 314. Andrographolide. Part I
    132. Herb–drug interaction of Andrographis paniculata extract and Andrographolide on the pharmacokinetics of theophylline in rats
    133. Determination of Andrographolide, deoxyAndrographolide and neoAndrographolide in the Chinese herb Andrographis paniculata by micellar electrokinetic capillary …
    134. Andrographolide exerts anti‐hepatitis C virus activity by up‐regulating haeme oxygenase‐1 via the p38 MAPK/N rf2 pathway in human hepatoma cells
    135. Therapeutic potentials of Andrographolide from Andrographis paniculata: a review
    136. Andrographolide targets androgen receptor pathway in castration-resistant prostate cancer
    137. Protective effect of Andrographolide against concanavalin A-induced liver injury
    138. Synthesis of Andrographolide cyclophosphate derivatives and their antitumor activities
    139. Andrographolide sulfonate ameliorates experimental colitis in mice by inhibiting Th1/Th17 response
    140. Biological activities and corresponding SARs of Andrographolide and its derivatives.
    141. Andrographolide could inhibit human colorectal carcinoma Lovo cells migration and invasion via down-regulation of MMP-7 expression
    142. Novel routes for the generation of structurally diverse labdane diterpenes from Andrographolide
    143. Activity of Andrographolide against chikungunya virus infection
    144. Chemistry of Andrographolide: formation of novel di-spiropyrrolidino and di-spiropyrrolizidino-oxindole adducts via one-pot three-component [3+ 2] azomethine ylide …
    145. Liquid and solid self-microemulsifying drug delivery systems for improving the oral bioavailability of Andrographolide from a crude extract of Andrographis paniculata
    146. Synthesis and biological evaluation of Andrographolide analogues as anti-cancer agents
    147. … of dynamic microwave-assisted extraction with high-performance liquid chromatography for determination of Andrographolide and dehydroAndrographolide in …
    148. Andrographolide and 14-deoxy-11, 12-didehydroAndrographolide inhibit cytochrome P450s in HepG2 hepatoma cells
    149. Cytotoxic activity and apoptosis-inducing potential of di-spiropyrrolidino and di-spiropyrrolizidino oxindole Andrographolide derivatives
    150. An investigation on the antimicrobial activity of Andrographis paniculata extracts and Andrographolide in vitro
    151. Effect and Mechanism of Andrographolide on the Recovery of Pseudomonas aeruginosa Susceptibility to Several Antibiotics
    152. A novel role of Andrographolide, an NF-kappa B inhibitor, on inhibition of platelet activation: the pivotal mechanisms of endothelial nitric oxide synthase/cyclic GMP
    153. Andrographolide suppresses melanin synthesis through Akt/GSK3β/β-catenin signal pathway
    154. Therapeutic potential of Andrographolide for treating endometriosis
    155. Andrographolide inhibits tumor angiogenesis via blocking VEGFA/VEGFR2-MAPKs signaling cascade
    156. Adaptogenic potential of Andrographolide: An active principle of the king of bitters (Andrographis paniculata)
    157. Determination of Andrographolide in human plasma by high-performance liquid chromatography/mass spectrometry
    158. Andrographolide inhibits osteopontin expression and breast tumor growth through down regulation of PI3 kinase/Akt signaling pathway
    159. Protective effect of Andrographis paniculata and Andrographolide on cyclophosphamide-induced urothelial toxicity
    160. Andrographolide inhibits ICAM-1 expression and NF-κB activation in TNF-α-treated EA. hy926 cells
    161. Screening and optimization of Andrographis paniculata (Burm. f.) Nees for total Andrographolide content, yield and its components
    162. Protective role of Andrographolide in bleomycin-induced pulmonary fibrosis in mice
    163. Andrographolide induces cell cycle arrest and apoptosis in human rheumatoid arthritis fibroblast-like synoviocytes
    164. Synthesis, structure–activity relationships and biological evaluation of dehydroAndrographolide and Andrographolide derivatives as novel anti-hepatitis B virus agents
    165. Jasmonate‐induced biosynthesis of Andrographolide in Andrographis paniculata
    166. A quantitative chemical proteomics approach to profile the specific cellular targets of Andrographolide, a promising anticancer agent that suppresses tumor metastasis
    167. Choleretic action of Andrographolide obtained from Andrographis paniculata in rats
    168. Solid lipid nanoparticles of anticancer drug Andrographolide: formulation, in vitro and in vivo studies
    169. Suppression of v-Src transformation by Andrographolide via degradation of the v-Src protein and attenuation of the Erk signaling pathway
    170. Taxifolin enhances Andrographolide-induced mitotic arrest and apoptosis in human prostate cancer cells via spindle assembly checkpoint activation
    171. Discovery of novel Andrographolide derivatives as cytotoxic agents
    172. Simultaneous determination of Andrographolide and dehydroAndrographolide in Andrographis paniculata and Chinese medicinal preparations by microemulsion …
    173. Anti-inflammatory effect of novel Andrographolide derivatives through inhibition of NO and PGE2 production
    174. Modifications of Andrographolide to increase some biological activities: a patent review (2006–2011)
    175. Andrographolide exhibits anti-invasive activity against colon cancer cells via inhibition of MMP2 activity
    176. Effect of Andrographolide and Kan Jang–fixed combination of extract SHA-10 and extract SHE-3–on proliferation of human lymphocytes, production of cytokines and …
    177. Synthesis and preliminary anti-HIV activities of Andrographolide derivatives
    178. Protective mechanism of Andrographolide against carbon tetrachloride-induced acute liver injury in mice
    179. Pancreatic effect of Andrographolide isolated from Andrographis paniculata (Burm. f.) Nees
    180. Efficient regioselective acylation of Andrographolide catalyzed by immobilized Burkholderia cepacia lipase
    181. Andrographolide inhibits human umbilical vein endothelial cell invasion and migration by regulating MMP-2 and MMP-9 during angiogenesis
    182. Andrographolide inhibits PI3K/AKT-dependent NOX2 and iNOS expression protecting mice against hypoxia/ischemia-induced oxidative brain injury
    183. Effect of Andrographolide on QS regulating virulence factors production in Pseudomonas aeruginosa
    184. Recrystallization of Andrographolide using the supercritical fluid antisolvent process
    185. Simultaneous estimation of Andrographolide and wedelolactone in herbal formulations
    186. Induction of heme oxygenase-1 and inhibition of TPA-induced matrix metalloproteinase-9 expression by Andrographolide in MCF-7 human breast cancer cells
    187. Hypolipidemic effects of Andrographolide and neoAndrographolide in mice and rats
    188. Effects of Andrographolide on sexual functions, vascular reactivity and serum testosterone level in rodents
    189. Modulation of the cannabinoid receptors by Andrographolide attenuates hepatic apoptosis following bile duct ligation in rats with fibrosis
    190. An in vitro study of anti-inflammatory activity of standardised Andrographis paniculata extracts and pure Andrographolide
    191. Effects of 14-alpha-lipoyl Andrographolide on quorum sensing in Pseudomonas aeruginosa
    192. Andrographolide sensitizes Ras-transformed cells to radiation in vitro and in vivo
    193. Protective role of 14-deoxy-11, 12-didehydroAndrographolide, a noncytotoxic analogue of Andrographolide, in allergic airway inflammation
    194. Engineered Andrographolide nanoparticles mitigate paracetamol hepatotoxicity in mice
    195. Bioavailability of Andrographolide and protection against carbon tetrachloride-induced oxidative damage in rats
    196. QSAR studies on Andrographolide derivatives as α-glucosidase inhibitors
    197. Antinociceptive and antiedematogenic activities of Andrographolide isolated from Andrographis paniculata in animal models
    198. Determination of Andrographolide and dehydroAndrographolide in rabbit plasma by on-line solid phase extraction of high-performance liquid chromatography
    199. Andrographolide: solving chemical instability and poor solubility by means of cocrystals
    200. Water-soluble Andrographolide sulfonate exerts anti-sepsis action in mice through down-regulating p38 MAPK, STAT3 and NF-κB pathways
    201. Andrographolide inhibits hypoxia-inducible factor-1 through phosphatidylinositol 3-kinase/AKT pathway and suppresses breast cancer growth
    202. The HLJ1 -targeting drug screening identified Chinese herb Andrographolide that can suppress tumour growth and invasion in non-small-cell lung …
    203. Modulation of immune response in mice immunised with an inactivated Salmonella vaccine and gavaged with Andrographis paniculata extract or Andrographolide
    204. Suppression of NF-κB signaling by Andrographolide with a novel mechanism in human platelets: regulatory roles of the p38 MAPK-hydroxyl radical-ERK2 cascade
    205. Synthesis and anticancer activity of some novel indolo [3, 2-b] Andrographolide derivatives as apoptosis-inducing agents
    206. Effect of dietary supplemented Andrographolide on growth, non-specific immune parameters and resistance against Aeromonas hydrophila in Labeo rohita (Hamilton)
    207. Physicochemical characteristics and oral bioavailability of Andrographolide complexed with hydroxypropyl-β-cyclodextrin
    208. Preparation and evaluation of Andrographolide-loaded microemulsion
    209. Andrographolide and 14-deoxy-11, 12-didehydroAndrographolide from Andrographis paniculata attenuate high glucose-induced fibrosis and apoptosis in murine …
    210. Effects of Andrographis paniculata extract and Andrographolide on hepatic cytochrome P450 mRNA expression and monooxygenase activities after in vivo …
    211. Induction of heme oxygenase 1 and inhibition of tumor necrosis factor α-induced intercellular adhesion molecule expression by Andrographolide in EA. hy926 cells
    212. Inactivation of PI3K/Akt signaling mediates proliferation inhibition and G2/M phase arrest induced by Andrographolide in human glioblastoma cells
    213. Andrographolide inhibits growth of acute promyelocytic leukaemia cells by inducing retinoic acid receptor‐independent cell differentiation and apoptosis
    214. Synergetic effect of Andrographis paniculata polysaccharide on diabetic nephropathy with Andrographolide
    215. Andrographolide radiosensitizes human ovarian cancer SKOV3 xenografts due to an enhanced apoptosis and autophagy
    216. 12-Amino-Andrographolide analogues: synthesis and cytotoxic activity
    217. Andrographolide stimulates neurogenesis in the adult hippocampus
    218. Andrographolide: A review of its anti-inflammatory activity via inhibition of NF-kappaB activation from computational chemistry aspects
    219. Synthesis and in vitro cytotoxicity of Andrographolide-19-oic acid analogues as anti-cancer agents
    220. Andrographolide suppress tumor growth by inhibiting TLR4/NF-κB signaling activation in insulinoma
    221. Andrographolide derivative AL‐1 improves insulin resistance through down‐regulation of NF‐κB signalling pathway
    222. Andrographolide analogue induces apoptosis and autophagy mediated cell death in U937 cells by inhibition of PI3K/Akt/mTOR pathway
    223. Enhancement of absorption and hepatoprotective potential through soya-phosphatidylcholine-Andrographolide vesicular system
    224. Anti-HIV activity of semisynthetic derivatives of Andrographolide and computational study of HIV-1 gp120 protein binding
    225. Andrographolide: progression in its modifications and applications–a patent review (2012–2014)
    226. Gender-associated modulation of inducible CYP1A1 expression by Andrographolide in mouse liver
    227. Constitutive and tumor necrosis factor-α-induced activation of nuclear factor-κB in adenomyosis and its inhibition by Andrographolide
    228. Synergistic increases of metabolism and oxidation–reduction genes on their expression after combined treatment with a CYP1A inducer and Andrographolide
    229. Cytotoxic biotransformed products from Andrographolide by Rhizopus stolonifer ATCC 12939
    230. Development of Andrographolide loaded PLGA microspheres: optimization, characterization and in vitro–in vivo correlation
    231. Elicitation of Andrographolide in the Suspension Cultures of Andrographis paniculata
    232. Enhanced protective activity of nano formulated Andrographolide against arsenic induced liver damage
    233. Andrographolide inhibits TNFα-induced ICAM-1 expression via suppression of NADPH oxidase activation and induction of HO-1 and GCLM expression through the …
    234. Andrographolide regulates epidermal growth factor receptor and transferrin receptor trafficking in epidermoid carcinoma (A‐431) cells
    235. Critical roles of cellular glutathione homeostasis and jnk activation in Andrographolide‐mediated apoptotic cell death in human hepatoma cells
    236. Preventive effects of Andrographolide on the development of diabetes in autoimmune diabetic NOD mice by inducing immune tolerance
    237. Mechanisms of Andrographolide‐induced platelet apoptosis in human platelets: regulatory roles of the extrinsic apoptotic pathway
    238. Cell type-dependent effects of Andrographolide on human cancer cell lines
    239. … of natural killer cell activity, antibody-dependent cellular cytotoxicity, and antibody-dependent complement-mediated cytotoxicity by Andrographolide in normal and …
    240. Modulation of thioacetamide-induced hepatic inflammations, angiogenesis and fibrosis by Andrographolide in mice
    241. Molecular interaction between Andrographolide and glutathione follows second order kinetics
    242. Herb–drug interaction prediction based on the high specific inhibition of Andrographolide derivatives towards UDP-glucuronosyltransferase (UGT) 2B7
    243. Modulation of the expression of the π class of glutathione S-transferase by Andrographis paniculata extracts and Andrographolide
    244. Andrographolide causes apoptosis via inactivation of STAT3 and Akt and potentiates antitumor activity of gemcitabine in pancreatic cancer
    245. Andrographolide Sensitizes the Cytotoxicity of Human Colorectal Carcinoma Cells Toward Cisplatin via Enhancing Apoptosis Pathways In Vitro and In Vivo
    246. Gastroprotective effect of Andrographolide sodium bisulfite against indomethacin-induced gastric ulceration in rats
    247. DETERMINATION OF Andrographolide IN COMMERCIAL ANDROGRAPHIS ( ANDROGRAPHIS PANICULATA ) PRODUCTS USING HPLC WITH …
    248. Andrographolide ameliorate rheumatoid arthritis by promoting the development of regulatory T cells
    249. Andrographolide induces vascular smooth muscle cell apoptosis through a SHP-1-PP2A-p38MAPK-p53 cascade
    250. Intracellular glutathione regulates Andrographolide-induced cytotoxicity on hepatoma Hep3B cells
    251. Bioavailability comparison between Andrographolide oral microemulsion and Andrographolide pill in rabbits
    252. Anticancer activity of Andrographolide semisynthetic derivatives
    253. A potential Andrographolide analogue against the replication of herpes simplex virus type 1 in vero cells
    254. Andrographolide suppresses proliferation of nasopharyngeal carcinoma cells via attenuating NF-B pathway
    255. A simple and sensitive HPLC–ESI-MS/MS method for the determination of Andrographolide in human plasma
    256. Andrographolide induces apoptosis in B16F-10 melanoma cells by inhibiting NF-κB-mediated bcl-2 activation and modulating p53-induced caspase-3 gene …
    257. Andrographolide-loaded PLGA-PEG-PLGA micelles to improve its bioavailability and anticancer efficacy
    258. Andrographolide inhibits the activation of NF‑κB and MMP‑9 activity in H3255 lung cancer cells
    259. Plant growth regulators induced changes in antioxidant potential and Andrographolide content in Andrographis paniculata Wall. ex Nees
    260. Acute toxicity and the effect of Andrographolide on porphyromonas gingivalis-induced hyperlipidemia in rats
    261. Andrographolide prevents human breast cancer-induced osteoclastic bone loss via attenuated RANKL signaling
    262. Evaluation of anti–bacterial and anti–oxidant potential of Andrographolide and echiodinin isolated from callus culture of Andrographis paniculata Nees
    263. Preparation of Andrographolide-loaded solid lipid nanoparticles and their in vitro and in vivo evaluations: characteristics, release, absorption, transports …
    264. A biochemical study on the gastroprotective effect of Andrographolide in rats induced with gastric ulcer
    265. Quantitative HPLC analysis of Andrographolide in Andrographis paniculata at two different stages of life cycle of plant
    266. Synergistic effect of 14-alpha-lipoyl Andrographolide and various antibiotics on the formation of biofilms and production of exopolysaccharide and pyocyanin by …
    267. Entrapment of Andrographolide in cross-linked alginate pellets: I. Formulation and evaluation of associated release kinetics
    268. Andrographolide attenuates tumor necrosis factor-alpha-induced insulin resistance in 3T3-L1 adipocytes
    269. Synthesis of new Andrographolide derivatives and evaluation of their antidyslipidemic, LDL-oxidation and antioxidant activity
    270. Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis
    271. A novel microwave-assisted extraction for the isolation of Andrographolide from Andrographis paniculata and its in vitro antioxidant activity
    272. Andrographolide, a novel NF-κB inhibitor, induces vascular smooth muscle cell apoptosis via a ceramide-p47phox-ROS signaling cascade
    273. A novel Andrographolide derivative AL‐1 exerts its cytotoxicity on K 562 cells through a ROS‐dependent mechanism
    274. Synthesis and biological evaluation of Andrographolide derivatives as potent anti-HIV agents
    275. Antioxidative and cytoprotective effects of Andrographolide against CCl4-induced hepatotoxicity in HepG2 cells
    276. Andrographis paniculata: a critical appraisal of extraction, isolation and quantification of Andrographolide and other active constituents
    277. Activation of α1A-adrenoceptor by Andrographolide to increase glucose uptake in cultured myoblast C2C12 cells
    278. Andrographolide induces apoptosis of C6 glioma cells via the ERK-p53-caspase 7-PARP pathway
    279. Neuroprotective effects of the Andrographolide analogue AL-1 in the MPP+/MPTP-induced Parkinson’s disease model in vitro and in mice
    280. In vitro susceptibilities of wild and drug resistant Leishmania donovani amastigote stages to Andrographolide nanoparticle: role of vitamin E derivative TPGS …
    281. Synthesis and discovery of Andrographolide derivatives as non-steroidal farnesoid X receptor (FXR) antagonists
    282. Andrographolide inhibits hepatoma cells growth and affects the expression of cell cycle related proteins.
    283. Andrographolide exerted its antimicrobial effects by upregulation of human β-defensin-2 induced through p38 MAPK and NF-κB pathway in human lung epithelial …
    284. Inhibitory effect of Andrographolide in 3T3-L1 adipocytes differentiation through the PPARγ pathway
    285. Andrographolide inhibits COX-2 expression in human fibroblast cells due to its interaction with arginine and histidine in cyclooxygenase site
    286. Synthesis and Biological Evaluation of Andrographolide Derivatives as Potent Anti‐HIV Agents
    287. Andrographolide exerts pro-osteogenic effect by activation of Wnt/β-Catenin signaling pathway in vitro
    288. Andrographolide, a novel bioactive phytoconstituent encapsulated in sustained release biodegradable nanoparticles
    289. Supercritical antisolvent precipitation of Andrographolide from Andrographis paniculata extracts: Effect of pressure, temperature and CO2 flow rate
    290. Design, synthesis, and biological evaluation of Andrographolide derivatives as potent hepatoprotective agents
    291. Aqueous Hydrotropic Solution as an Efficient Solubilizing Agent for Andrographolide from Andrographis paniculata Leaves
    292. Cytotoxic potential of dispirooxindolo/acenaphthoquino Andrographolide derivatives against MCF-7 cell line
    293. Nanoparticle engineering enhances anticancer efficacy of Andrographolide in MCF-7 cells and mice bearing EAC
    294. Suppression of matrix metalloproteinase-9 expression by Andrographolide in human monocytic THP-1 cells via inhibition of NF-κB activation
    295. A facile route for the synthesis of limonidilactone analogues from Andrographolide
    296. Andrographolide prevents high-fat diet–induced obesity in C57BL/6 mice by suppressing the sterol regulatory element-binding protein pathway
    297. Pharmacokinetic analysis and tissue distribution of Andrographolide in rat by a validated LC-MS/MS method
    298. Andrographolide and kalmegh (Andrographis paniculata) extract: effect on intestinal brush-border membrane-bound hydrolases.
    299. Specificity and inhibitory mechanism of Andrographolide and its analogues as antiasthma agents on NF-κB p50
    300. In vitro & in vivo correlation of release behavior of Andrographolide from silica and PEG assisted silica gel matrix
    301. Andrographolide activates the canonical Wnt signalling pathway by a mechanism that implicates the non-ATP competitive inhibition of GSK-3β: autoregulation of GSK …
    302. Optimization of microwave assisted extraction of Andrographolide from Andrographis paniculata and its comparison with refluxation extraction method
    303. Identification, purification and quantification of Andrographolide from Andrographis paniculata (burm. F.) Nees by HPTLC at different stages of life cycle of crop
    304. Flow injection spectrophotometric determination of Andrographolide from Andrographis paniculata
    305. Synthesis of new ent-labdane diterpene derivatives from Andrographolide and evaluation on cytotoxic activities
    306. Andrographis paniculata extract and Andrographolide modulate the hepatic drug metabolism system and plasma tolbutamide concentrations in rats
    307. In vitro determination of the effect of Andrographis paniculata extracts and Andrographolide on human hepatic cytochrome P450 activities
    308. Andrographolide inhibits proliferation of human lung cancer cells and the related mechanisms
    309. Potential compounds for oral cancer treatment: resveratrol, nimbolide, lovastatin, bortezomib, vorinostat, berberine, pterostilbene, deguelin, Andrographolide …
    310. Preparation and characterisation of Andrographolide niosomes and its anti-hepatocellular carcinoma activity
    311. … of Uterine Contractility, and Alleviation of Generalized Hyperalgesia in Mice With Induced Adenomyosis by Levo-Tetrahydropalmatine (l-THP) and Andrographolide
    312. Solubility of Andrographolide in various solvents from (288.2 to 323.2) K
    313. Mapping study of an ultrasonic bath for the extraction of Andrographolide from Andrographis paniculata using ultrasound
    314. In situ imaging and proteome profiling indicate Andrographolide is a highly promiscuous compound
    315. Andrographolide inhibits the migration, invasion and matrix metalloproteinase expression of rheumatoid arthritis fibroblast-like synoviocytes via inhibition of HIF-1α …
    316. Enzymatic synthesis and antibacterial activity of Andrographolide derivatives
    317. Effect of the derivatives of Andrographolide on the morphology of Bacillus subtilis
    318. Oviposition deterrent activity of Andrographolide against the diamondback moth (DBM), Plutella xylostella (Lepidoptera: Yponomeutidae)
    319. Stability of Andrographolide in powdered Andrographis herb under accelerated conditions
    320. Andrographolide drop-pill in treatment of acute upper respiratory tract infection with external wind-heat syndrome: a multicenter and randomized controlled trial
    321. Anti-diabetic effect of a combination of Andrographolide-enriched extract of Andrographis paniculata (Burm f.) Nees and asiaticoside-enriched extract of Centella …
    322. FT-IR spectra and vibrational spectroscopy of Andrographolide
    323. Determination of six components of Andrographis paniculata extract and one major metabolite of Andrographolide in rat plasma by liquid chromatography–tandem …
    324. Eudragit® EPO based nanoparticle suspension of Andrographolide: in vitro and in vivo
    325. Andrographolide downregulates the v-Src and Bcr-Abl oncoproteins and induces Hsp90 cleavage in the ROS-dependent suppression of cancer malignancy
    326. Potency of Andrographolide as an antitumor compound in BHC-induced liver damage
    327. Effects of Andrographolide on the pharmacokinetics of aminophylline and doxofylline in rats
    328. Anti-proliferative and pro-apoptotic effects from sequenced combinations of Andrographolide and cisplatin on ovarian cancer cell lines
    329. Protective Effects of Andrographis paniculata Extract and Pure Andrographolide Against Chronic Stress-Triggered Pathologies in Rats
    330. Induction of apoptosis in cholangiocarcinoma by an Andrographolide analogue is mediated through topoisomerase II alpha inhibition
    331. Inhibition of topoisomerase II α activity and induction of apoptosis in mammalian cells by semi-synthetic Andrographolide analogues
    332. Enhanced synthesis of Andrographolide by Aspergillus niger and Penicillium expansum elicitors in cell suspension culture of Andrographis paniculata (Burm …
    333. Preparation and in vitro Drug-release Behavior of Andrographolide Liposomes
    334. Enhanced hepatoprotective activity of Andrographolide complexed with a biomaterial
    335. Anti-tumor initiating potential of Andrographolide in 7, 12-dimethylbenz [a] anthracene induced hamster buccal pouch carcinogenesis
    336. Andrographolide: a potent antituberculosis compound that targets aminoglycoside 2′-N-acetyltransferase in Mycobacterium tuberculosis
    337. Proteomic alterations in mouse kidney induced by Andrographolide sodium bisulfite
    338. Antibacterial Activity of Ethanolic Leaf Extract of Andrographis paniculata Nees (Acanthaceae) and Its Bioactive Compound Andrographolide.
    339. Engineered Andrographolide nanosystems for smart recovery in hepatotoxic conditions
    340. On the structure of Andrographolide
    341. Effect of Andrographolide on monkey hepatocytes against galactosamine induced cell toxicity: an in-vitro study
    342. Efficient and highly regioselective acylation of Andrographolide catalyzed by lipase in acetone
    343. Andrographolide inhibits the expression and metabolic activity of cytochrome P450 3A4 in the modified Caco-2 cells
    344. Andrographolide reduces proliferation and migration of lens epithelial cells by modulating PI3K/Akt pathway
    345. Improved inhibitory activities against tumor-cell migration and invasion by 15-benzylidene substitution derivatives of Andrographolide
    346. Andrographolide decreased VEGFD expression in hepatoma cancer cells by inducing ubiquitin/proteasome-mediated cFos protein degradation
    347. Effects of Andrographolide and 14-deoxy-11, 12-didehydroAndrographolide on cultured primary astrocytes and PC12 cells
    348. Inhibition of MDA-MB-231 breast cancer cell migration and invasion activity by Andrographolide via suppression of nuclear factor-κB-dependent matrix …
    349. Technical optimization of the extraction of Andrographolide by supercritical CO2
    350. Quinone reductase (QR) inducers from Andrographis paniculata and identification of molecular target of Andrographolide
    351. Andrographolide inhibits HMGB 1‐induced inflammatory responses in human umbilical vein endothelial cells and in murine polymicrobial sepsis
    352. Modulation of lianbizi injection (Andrographolide) on some immune functions
    353. Protective effects of Andrographolide analogue AL-1 on ROS-induced RIN-mβ cell death by inducing ROS generation
    354. Andrographolide Protects against Cigarette Smoke‐Induced Lung Inflammation through Activation of Heme Oxygenase‐1
    355. Dry state microcrystals stabilized by an HPMC film to improve the bioavailability of Andrographolide
    356. Rat Intestine Absorption Characteristics Study on Andrographolide with Isolated Everted Intestine Model [J]
    357. Cellular glutathione content modulates the effect of Andrographolide on β-naphthoflavone-induced CYP1A1 mRNA expression in mouse hepatocytes
    358. Synthesis and evaluation of anticancer activity of novel Andrographolide derivatives
    359. Andrographolide sodium bisulfate-induced apoptosis and autophagy in human proximal tubular endothelial cells is a ROS-mediated pathway
    360. Effect of integrated nutrient management on Andrographolide content of Andrographis paniculata
    361. Rapid extraction of Andrographolide from Andrographis paniculata Nees by three phase partitioning and determination of its antioxidant activity
    362. Therapeutic potential of Andrographolide isolated from the leaves of Andrographis paniculata Nees for treating lung adenocarcinomas
    363. Improving the efficacy of conventional therapy by adding Andrographolide sulfonate in the treatment of severe hand, foot, and mouth disease: a randomized controlled …
    364. Regioselective glucuronidation of Andrographolide and its major derivatives: metabolite identification, isozyme contribution, and species differences
    365. Prediction of the relationship between the structural features of Andrographolide derivatives and α-glucosidase inhibitory activity: a quantitative structure-activity …
    366. Column chromatography for isolation of Andrographolide from in vitro grown medicinal plant Andrographis paniculata Wall. ex Nees
    367. A pilot study on the use of Andrographolide to treat symptomatic adenomyosis
    368. Selective reduction of Andrographolide
    369. A novel bioactivity of Andrographolide from Andrographis paniculata on cerebral ischemia/reperfusion-induced brain injury through induction of cerebral endothelial …
    370. Role of plant growth regulators for improving Andrographolide in Andrographis paniculata
    371. Fast batch to continuous transposition: application to the extraction of Andrographolide from plants
    372. Advances in study on anti-tumor mechanism of Andrographolide
    373. Andrographolide: The active principle of Kalmegh
    374. Antifertility studies of curcumin and Andrographolide combination in female rats
    375. Determination of apparent oil-water partition coefficient of Andrographolide and dehydroAndrographolide and effect of pH on them
    376. Investigation of basic physical and chemical properties of Andrographolide
    377. Separation and Enrichment of Andrographolide by Solvent Floatation [J]
    378. Comparative pharmacokinetic studies of Andrographolide and its metabolite of 14‐deoxy‐12‐hydroxy‐Andrographolide in rat by ultra‐performance liquid …
    379. Andrographolide antagonizes cigarette smoke extract-induced inflammatory response and oxidative stress in human alveolar epithelial A549 cells through induction …
    380. Novel bioconversion products of Andrographolide by Aspergillus ochraceus and their cytotoxic activities against human tumor cell lines
    381. A novel semi-synthetic Andrographolide analogue A5 inhibits tumor angiogenesis via blocking the VEGFR2-p38/ERK1/2 signal pathway
    382. CHP1002, a novel Andrographolide derivative, inhibits pro-inflammatory inducible nitric oxide synthase and cyclooxygenase-2 expressions in RAW264. 7 …
    383. Acute and subacute toxicity study of Andrographolide bioactive in rodents: Evidence for the medicinal use as an alternative medicine
    384. Andrographolide as an anti-H1N1 drug and the mechanism related to retinoic acid-inducible gene-I-like receptors signaling pathway
    385. Experimental and modelling studies of Andrographolide extraction from andrographis paniculata.
    386. Synthesis and in vitro cytotoxicity of novel C-12 substituted-14-deoxy-Andrographolide derivatives as potent anti-cancer agents
    387. In-vivo effect of Andrographolide on alveolar bone resorption induced by Porphyromonas gingivalis and its relation with antioxidant enzymes
    388. Inhibition of matrix metalloproteinases and inducible nitric oxide synthase by Andrographolide in human osteoarthritic chondrocytes
    389. Preparation and Recognition Properties of Andrographolide Molecularly Imprinted Ploymer Microspheres
    390. SAR studies of 3, 14, 19-derivatives of Andrographolide on anti-proliferative activity to cancer cells and toxicity to zebrafish: an in vitro and in vivo study
    391. The genotoxicity and cytotoxicity assessments of Andrographolide in vitro
    392. Multiple shoot induction and jasmonic versus salicylic acid driven elicitation for enhanced Andrographolide production in Andrographis paniculata
    393. Andrographolide suppresses epithelial mesenchymal transition by inhibition of MAPK signalling pathway in lens epithelial cells
    394. Synthesis and preliminary antihyperlipidaemic activities evaluation of Andrographolide derivatives
    395. Positive therapy of Andrographolide in vocal fold leukoplakia
    396. Andrographolide, a novel NF-κB inhibitor, inhibits vascular smooth muscle cell proliferation and cerebral endothelial cell inflammation
    397. Refined Crystal and Molecular Structure of Andrographolide—Diterpene
    398. Application of gas anti-solvent process to the recovery of Andrographolide from Andrographis paniculatanees
    399. Evaluation of the effect of Andrographolide on atherosclerotic rabbits induced by Porphyromonas gingivalis
    400. Potential anti-angiogenic sulfates of Andrographolide
    401. Regeneration of Andrographis paniculata Nees: analysis of genetic fidelity and Andrographolide content in micropropagated plants
    402. Andrographolide inhibits nuclear factor-B activation through JNK-Akt-p65 signaling cascade in tumor necrosis factor-α-Stimulated vascular smooth muscle cells
    403. Synthesis and preliminary COX-2 expression inhibitory activities of Andrographolide derivatives
    404. Antitussive arabinogalactan of Andrographis paniculata demonstrates synergistic effect with Andrographolide
    405. Membrane transport of Andrographolide in artificial membrane and rat small intestine
    406. Development and validation of HPTLC method for the determination of Andrographolide from Andrographis paniculata (whole plant)
    407. Anti-inflammatory effect of Andrographolide microemulsion [J]
    408. Pharmacological activity effect of Andrographolide
    409. Simultaneous determination of 9‐dehydro‐17‐hydro‐Andrographolide and sodium 9‐dehydro‐17‐hydro‐Andrographolide‐19‐yl sulfate in rat plasma by UHPLC‐ESI …
    410. Clinical efficacy of Andrographolide sulfonate in the treatment of severe hand, foot, and mouth disease (HFMD) is dependent upon inhibition of neutrophil activation
    411. Andrographolide attenuates LPS-induced cardiac malfunctions through inhibition of IκB phosphorylation and apoptosis in mice
    412. Microwave and Ultrasonic Assisted Extraction of Andrographolide from Andrographis paniculata [J]
    413. Influence of magnetic field on the morphology of the Andrographolide crystal from supercritical carbon dioxide extraction–crystallization
    414. Andrographolide, a major component of Andrographis paniculata leaves, has the neuroprotective effects on glutamate-induced HT22 cell death
    415. SRS06, a new semisynthetic Andrographolide derivative with improved anticancer potency and selectivity, inhibits nuclear factor-κB nuclear binding in the A549 non …
    416. Determination of Andrographolide and 14-deoxy-11, 12-didehydroAndrographolide in Compound Chuanxinlian tablets by HPLC
    417. Influence of light intensity on gas exchange, herbage yield and Andrographolide content in Andrographis paniculata (Nees.)
    418. MODELING OF SUPERCRITICAL CARBON DIOXIDE EXTRACTION OF Andrographolide FROM ANDROGRAPHIS PANICULATA LEAVES
    419. HPLC Determination of Andrographolide, NeoAndrographolide and Dehydro-Andrographolide in Biological Fluids
    420. Pretreatment with Andrographolide Pills® Attenuates Lipopolysaccharide‐Induced Pulmonary Microcirculatory Disturbance and Acute Lung Injury in Rats
    421. Establishment of In Vitro Adventitious Root Cultures and Analysis of Andrographolide in Andrographis Paniculata
    422. Efficacy of Andrographolide on pupal-adult transformation of Corcyra cephalonica Stainton
    423. Andrographolide sodium bisulphite-induced inactivation of urease: inhibitory potency, kinetics and mechanism
    424. Synthesis and Biological Evaluation of Andrographolide C‐Glycoside Derivatives as α‐Glycosidase Inhibitors
    425. Andrographolide suppresses high glucose‐induced fibronectin expression in mesangial cells via inhibiting the AP‐1 pathway
    426. Biochemical estimation and quantitative determination of medicinally important Andrographolide in Andrographis peniculata at different growth stages.
    427. Two novel creatinine adducts of Andrographolide in human urine
    428. Effect of aging on Andrographolide content in Andrographis paniculata
    429. Insights into the antiatherogenic molecular mechanisms of Andrographolide against Porphyromonas gingivalis-induced atherosclerosis in rabbits
    430. Evaluating Andrographolide as a potent inhibitor of NS3-4A protease and its drug-resistant mutants using in silico approache