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COMBOS
TESTIMONIALS
CART
INGREDIENTS
2-Deoxy-D-Glucose (2DG)
Acacia Cyanophylla Flower
Acori Graminei Rhizoma
Aegle Marmelos Correa
Agaricus Blazei
Aged Garlic Extract
Aframomum Melegueta
Aloe Arborescens
Albizia
Alpinia Officinarum
Alternanthera Sessilis
American Ginseng
Amygdalin
Anacyclus Pyrethrum
Angelica Archangelica
Angelica Sinensis
Antrodia
Artichoke Leaf
Artocarpin
Ajuga Turkestanica
Ashwagandha
Aspalathin
Astragalus Complanatus
Avena Sativa
Bacopa Monnieri
Bavachin
Bee Pollen
Betulinic Acid
Boswellic Acid
Brevilin A
Campesterol
Casticin
Chrysin
Cinnamomum Zeylanicum
Citrullus Colocynthis
Citrus Reticulata Peel
Codonopsis
Costunolide
Cucurbitacin D
Daidzein
Decursin
Delphinidin
Digitalis Purprea (Digoxin)
Diosmin
Embelin
Gallic Acid
Glycitein
Glycyrrhizin
Hyperforin
Icariin
Isorhamnetin
Isoorientin
Isovitexin
Jaceosidin
Kaempferol
Kurarinone
Lemon balm
Licoricidin
Lipoic acid
Lupeol
Magnolol
Mulberry Leaf
Naringenin
Nobiletin
Oleacein
Oleanolic acid
Oridonin
Parthenolide
Phloroglucinol
Piceatannol
Pristimerin
Proanthocyanidins
Procyanidin B3
Pseudolaric acid b
Pterostilbene
Rutin
Solidago Virgaurea
Tangeretin
Taraxasterol
Trichostatin A
Wedelolactone
Wogonin
Yerba Mate
ABOUT
SCIENTIFIC STUDIES
ALLERGIES & CYTOKINES
ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS
ADVANCED GLYCATION END PRODUCTS (AGES)
AMPK
ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS
ANTI-APOPTOTIC PATHWAYS
ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS
ANTI COVID-19 EFFECTS OF FLAVONOIDS AND POLYPHENOLS (1000 SCIENTIFIC STUDIES)
ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS
ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS
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BCL-2
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BCL-XL
BECLIN-1 & AUTOPHAGY
BH3 MIMETICS
BIM aka BCL2L11
BMI-1
CARDIAC GLYCOSIDES
CENTENARIANS
CYP2E1
CYTOKINES IN PAIN, INFLAMMATION & AGING
DAF-16
EPIGENETIC MODIFIERS
FGF21
KLOTHO
FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN
FOXO3
FOXO4
HMGB1
HSP90 INHIBITORS
HYPERINSULINEMIA
IKK
IL-6/STAT3
INFECTOBESITY
INFLAMMATION & ANXIETY
INFLAMMATION & CANCER
INFLAMMATION & DEPRESSION
INFLAMMATION & OBESITY
INFLAMMAGING
INSULIN & AGING
JAK INHIBITION ALLEVIATES SASP
JNK ACTIVATION PREVENTS PREMATURE SENESCENCE
KETONE BODIES
KETOGENIC DIET
LIFESPAN EXTENSION
MATRIX METALLOPROTEINASES (MMPs)
MCL-1
MDM2 INHIBITION AS SASP INHIBITOR
MSG (MONOSOSODIUM GLUTAMATE)
MYOSTATIN INHIBITION
MYOSTATIN INHIBITION PRESERVES MUSCLE
mTOR: THE RAPID AGING PATHWAY
NEUROINFLAMMATION
NMDA & ANXIETY & DEPRESSION
NMDA RECEPTOR AND FEAR
NOOTROPICS
NRF2: MASTER REGULATOR OF THE AGING PROCESS
NF-KB
ONCOGENE ACTIVATION INDUCED SENESCENCE
OXIDATIVE STRESS & AGING
P16INK4A
P38MAPK
P53: TUMOR SUPRESSOR
PHYTOECDYSTEROIDS
PPARY2
PREMATURE SENESCENCE
SASP & ADIPOSE TISSUE
SENESCENT CELLS, SASP & SENOLYTICS
SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG)
SKIN PHOTOAGING (Preventing & Repairing)
SIRT1 & LONGEVITY
SUGAR & AGING
STAT3
TELOMERE SHORTENING & PREMATURE AGING
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FAQ
CONTACT
INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL
The Ultimate Dry Fasting Resource
0
Klotho
July 30, 2019
HSP90
January 6, 2020
Crucial role of
p53
-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
Human SIR2 deacetylates
p53
and antagonizes PML/
p53
‐induced cellular senescence
Senescence and tumour clearance is triggered by
p53
restoration in murine liver carcinomas
Oncogenic ras provokes premature cell senescence associated with accumulation of
p53
and p16INK4a
PML regulates
p53
acetylation and premature senescence induced by oncogenic Ras
Regulation of cellular senescence by
p53
Reversal of human cellular senescence: roles of the
p53
and p16 pathways
Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the
p53
tumor suppressor
A role for both RB and
p53
in the regulation of human cellular senescence
Senescence and aging: the critical roles of
p53
A senescence program controlled by
p53
and p16INK4a contributes to the outcome of cancer therapy
Paradoxical suppression of cellular senescence by
p53
Skp2 targeting suppresses tumorigenesis by Arf-
p53
-independent cellular senescence
Premature senescence involving
p53
and p16 is activated in response to constitutive MEK/MAPK mitogenic signaling
Oncogenic ras and
p53
cooperate to induce cellular senescence
Escape from senescence in human diploid fibroblasts induced directly by mutant
p53
.
Wild-type
p53
triggers a rapid senescence program in human tumor cells lacking functional
p53
Telomere shortening triggers senescence of human cells through a pathway involving ATM,
p53
, and p21CIP1, but not p16INK4a
Tumor suppression in the absence of
p53
-mediated cell-cycle arrest, apoptosis, and senescence
JunD protects cells from
p53
-dependent senescence and apoptosis
Mutant
p53
drives metastasis and overcomes growth arrest/senescence in pancreatic cancer
p53
, ROS and senescence in the control of aging
Adriamycin-induced senescence in breast tumor cells involves functional
p53
and telomere dysfunction
Pathways connecting telomeres and
p53
in senescence, apoptosis, and cancer
Reversal of senescence in mouse fibroblasts through lentiviral suppression of
p53
p53
-independent upregulation of miR-34a during oncogene