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    Solidago virgaurea
    January 15, 2020
    Thymoquinone
    January 15, 2020

    Sulforaphane

    1. Anticarcinogenic activities of Sulforaphane and structurally related synthetic norbornyl isothiocyanates.
    2. Multi-targeted prevention of cancer by Sulforaphane
    3. Molecular basis for chemoprevention by Sulforaphane: a comprehensive review
    4. Identification of Nrf2-regulated genes induced by the chemopreventive agent Sulforaphane by oligonucleotide microarray
    5. A novel mechanism of chemoprotection by Sulforaphane: inhibition of histone deacetylase
    6. Sulforaphane treatment of autism spectrum disorder (ASD)
    7. Nuclear factor κB is a molecular target for Sulforaphane-mediated anti-inflammatory mechanisms
    8. Sulforaphane as a promising molecule for fighting cancer
    9. Chemoprotection by Sulforaphane: keep one eye beyond Keap1
    10. Protective effect of Sulforaphane against oxidative stress: recent advances
    11. Molecular targets of dietary phenethyl isothiocyanate and Sulforaphane for cancer chemoprevention
    12. Sulforaphane, a dietary component of broccoli/broccoli sprouts, inhibits breast cancer stem cells
    13. Antimetastatic activity of Sulforaphane
    14. Potent induction of phase 2 enzymes in human prostate cells by Sulforaphane
    15. Sulforaphane inhibits histone deacetylase in vivo and suppresses tumorigenesis in Apcmin mice
    16. Sulforaphane reduces infarct volume following focal cerebral ischemia in rodents
    17. Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, Sulforaphane and Sulforaphane nitrile
    18. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells
    19. CYP2E1-mediated mechanism of anti-genotoxicity of the broccoli constituent Sulforaphane
    20. Preclinical and clinical evaluation of Sulforaphane for chemoprevention in the breast
    21. Heating decreases epithiospecifier protein activity and increases Sulforaphane formation in broccoli
    22. Keap1–nrf2 signaling: a target for cancer prevention by Sulforaphane
    23. Dietary Sulforaphane, a histone deacetylase inhibitor for cancer prevention
    24. Chemoprevention of colonic aberrant crypt foci in Fischer rats by Sulforaphane and phenethyl isothiocyanate
    25. Modification of keap1 cysteine residues by Sulforaphane
    26. Sulforaphane induces cell type–specific apoptosis in human breast cancer cell lines
    27. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo [a] pyrene-induced stomach tumors
    28. A Sulforaphane analogue that potently activates the Nrf2-dependent detoxification pathway
    29. Sulforaphane suppressed LPS-induced inflammation in mouse peritoneal macrophages through Nrf2 dependent pathway
    30. Identification of sensor cysteines in human Keap1 modified by the cancer chemopreventive agent Sulforaphane
    31. Electrophilic tuning of the chemoprotective natural product Sulforaphane
    32. Disposition of glucosinolates and Sulforaphane in humans after ingestion of steamed and fresh broccoli
    33. Sulforaphane as a potential protective phytochemical against neurodegenerative diseases
    34. Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells
    35. Thermal degradation of Sulforaphane in aqueous solution
    36. Sulforaphane causes epigenetic repression of hTERT expression in human breast cancer cell lines
    37. Oral Sulforaphane increases Phase II antioxidant enzymes in the human upper airway
    38. Sulforaphane and its glutathione conjugate but not Sulforaphane nitrile induce UDP-glucuronosyl transferase (UGT1A1) and glutathione transferase (GSTA1) in …
    39. Sulforaphane targets pancreatic tumour-initiating cells by NF-κB-induced antiapoptotic signalling
    40. Discovery and development of Sulforaphane as a cancer chemopreventive phytochemical1
    41. Sulforaphane-induced cell death in human prostate cancer cells is initiated by reactive oxygen species
    42. Sulforaphane improves cognitive function administered following traumatic brain injury
    43. Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cells
    44. Sulforaphane retards the growth of human PC-3 xenografts and inhibits HDAC activity in human subjects
    45. Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP and PC-3 prostate epithelial cells
    46. Cancer chemopreventive potential of sulforamate, a novel analogue of Sulforaphane that induces phase 2 drug-metabolizing enzymes
    47. Synergistic activity of sorafenib and Sulforaphane abolishes pancreatic cancer stem cell characteristics
    48. Sulforaphane: a naturally occurring mammary carcinoma mitotic inhibitor, which disrupts tubulin polymerization
    49. Glutathione S-transferase M1 polymorphism and metabolism of Sulforaphane from standard and high-glucosinolate broccoli
    50. Protective effect of Sulforaphane against dopaminergic cell death
    51. Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation
    52. Preparative HPLC Method for the Purification of Sulforaphane and Sulforaphane Nitrile from Brassica oleracea
    53. Sulforaphane protects against cisplatin-induced nephrotoxicity
    54. Gas chromatography/mass spectrometry method for the determination of Sulforaphane and Sulforaphane nitrile in broccoli
    55. Growth inhibition, cell-cycle arrest and apoptosis in human T-cell leukemia by the isothiocyanate Sulforaphane
    56. Sulforaphane enhances aquaporin‐4 expression and decreases cerebral edema following traumatic brain injury
    57. Induction of phase 2 genes by Sulforaphane protects retinal pigment epithelial cells against photooxidative damage
    58. Sulforaphane prevents mouse skin tumorigenesis during the stage of promotion
    59. Determination of Sulforaphane in broccoli and cabbage by high-performance liquid chromatography
    60. Sulforaphane suppresses LPS-induced inflammation in primary rat microglia
    61. In vivo pharmacokinetics and regulation of gene expression profiles by isothiocyanate Sulforaphane in the rat
    62. Sulforaphane inhibits human MCF-7 mammary cancer cell mitotic progression and tubulin polymerization
    63. Inhibition of angiogenesis and endothelial cell functions are novel Sulforaphane-mediated mechanisms in chemoprevention
    64. Inhibition of cytochromes P-450 and induction of glutathione S-transferases by Sulforaphane in primary human and rat hepatocytes
    65. Sulforaphane-induced G2/M phase cell cycle arrest involves checkpoint kinase 2-mediated phosphorylation of cell division cycle 25C
    66. High glucosinolate broccoli: a delivery system for Sulforaphane
    67. Absorption/metabolism of Sulforaphane and quercetin, and regulation of phase II enzymes, in human jejunum in vivo
    68. Autophagy inhibition enhances Sulforaphane-induced apoptosis in human breast cancer cells
    69. Dietary Sulforaphane-rich broccoli sprouts reduce colonization and attenuate gastritis in Helicobacter pylori–infected mice and humans
    70. Sulforaphane increases drug-mediated cytotoxicity toward cancer stem-like cells of pancreas and prostate
    71. The dietary isothiocyanate Sulforaphane is an antagonist of the human steroid and xenobiotic nuclear receptor
    72. Sulforaphane induces caspase-mediated apoptosis in cultured PC-3 human prostate cancer cells and retards growth of PC-3 xenografts in vivo
    73. Sulforaphane: translational research from laboratory bench to clinic
    74. Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and Sulforaphane occurring preferentially in …
    75. Transcriptome analysis of human colon Caco-2 cells exposed to Sulforaphane
    76. Targeting cell cycle machinery as a molecular mechanism of Sulforaphane in prostate cancer prevention
    77. Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6
    78. Inhibition of 7, 12-dimethylbenz (a) anthracene-induced skin tumorigenesis in C57BL/6 mice by Sulforaphane is mediated by nuclear factor E2–related factor 2
    79. Biotransformation of the naturally occurring isothiocyanate Sulforaphane in the rat: identification of phase I metabolites and glutathione conjugates
    80. Synergistic effect of combination of phenethyl isothiocyanate and Sulforaphane or curcumin and Sulforaphane in the inhibition of inflammation
    81. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by Sulforaphane-containing broccoli sprout extracts
    82. Modulation of phase II enzymes by Sulforaphane: implications for its cardioprotective potential
    83. Sulforaphane protects brains against hypoxic–ischemic injury through induction of Nrf2-dependent phase 2 enzyme
    84. Sulforaphane as a promising molecule for fighting cancer
    85. Sulforaphane enhances Nrf2 expression in prostate cancer TRAMP C1 cells through epigenetic regulation
    86. Sulforaphane induces thioredoxin through the antioxidant-responsive element and attenuates retinal light damage in mice
    87. Mechanism of Sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells
    88. Sulforaphane suppresses angiogenesis and disrupts endothelial mitotic progression and microtubule polymerization
    89. Epithiospecifier Protein from Broccoli (Brassica oleracea L. ssp. italica) Inhibits Formation of the Anticancer Agent Sulforaphane
    90. Antiproliferative activity of Sulforaphane in Akt-overexpressing ovarian cancer cells
    91. Sulforaphane suppresses oligomerization of TLR4 in a thiol-dependent manner
    92. Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: studies with Sulforaphane and garlic organosulfur compounds
    93. Induction of the phase 2 response in mouse and human skin by Sulforaphane-containing broccoli sprout extracts
    94. Sulforaphane protects ischemic injury of hearts through antioxidant pathway and mitochondrial KATP channels
    95. Cancer chemoprevention of intestinal polyposis in ApcMin/+ mice by Sulforaphane, a natural product derived from cruciferous vegetable
    96. Promoter de-methylation of cyclin D2 by Sulforaphane in prostate cancer cells
    97. Histone deacetylases as targets for dietary cancer preventive agents: lessons learned with butyrate, diallyl disulfide, and Sulforaphane
    98. Metabolism and tissue distribution of Sulforaphane in Nrf2 knockout and wild-type mice
    99. Sulforaphane protects kidneys against ischemia-reperfusion injury through induction of the Nrf2-dependent phase 2 enzyme
    100. Sulforaphane inhibits angiogenesis through activation of FOXO transcription factors
    101. Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by Sulforaphane
    102. Prevention by Sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation
    103. Formation of glucoraphanin by chemoselective oxidation of natural glucoerucin: a chemoenzymatic route to Sulforaphane
    104. Cultivation conditions and selenium fertilization alter the phenolic profile, glucosinolate, and Sulforaphane content of broccoli
    105. Gene expression profiles induced by cancer chemopreventive isothiocyanate Sulforaphane in the liver of C57BL/6J mice and C57BL/6J/Nrf2 (−/−) mice
    106. Regulation of the Keap1/Nrf2 system by chemopreventive Sulforaphane: implications of posttranslational modifications
    107. Bioavailability and kinetics of Sulforaphane in humans after consumption of cooked versus raw broccoli
    108. Bax and Bak are required for apoptosis induction by Sulforaphane, a cruciferous vegetable–derived cancer chemopreventive agent
    109. Sulforaphane protects against cytokine-and streptozotocin-induced β-cell damage by suppressing the NF-κB pathway
    110. Amelioration of Alzheimer’s disease by neuroprotective effect of Sulforaphane in animal model
    111. Sulforaphane and quercetin modulate PhIP–DNA adduct formation in human HepG2 cells and hepatocytes
    112. Phenethyl isothiocyanate and Sulforaphane and their N-acetylcysteine conjugates inhibit malignant progression of lung adenomas induced by tobacco carcinogens in …
    113. Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells
    114. Dietary agents as histone deacetylase inhibitors: Sulforaphane and structurally related isothiocyanates
    115. Sulforaphane protects liver injury induced by intestinal ischemia reperfusion through Nrf2-ARE pathway
    116. … protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: the indirect antioxidant effects of Sulforaphane
    117. Sulforaphane protects astrocytes against oxidative stress and delayed death caused by oxygen and glucose deprivation
    118. Impact of Nrf2 on UVB‐induced skin inflammation/photoprotection and photoprotective effect of Sulforaphane
    119. Induction of phase II detoxification enzymes in rats by plant-derived isothiocyanates: comparison of allyl isothiocyanate with Sulforaphane and related compounds
    120. Suppression of NF-κB and NF-κB-regulated gene expression by Sulforaphane and PEITC through IκBα, IKK pathway in human prostate cancer PC-3 cells
    121. Neuroprotective effect of Sulforaphane in 6-hydroxydopamine-lesioned mouse model of Parkinson’s disease
    122. Design and synthesis of bifunctional isothiocyanate analogs of Sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication …
    123. Asymmetric synthesis of chiral sulfinate esters and sulfoxides. Synthesis of Sulforaphane
    124. Prevention of diabetic nephropathy by Sulforaphane: possible role of Nrf2 upregulation and activation
    125. Inhibition of autophagy potentiates Sulforaphane-induced apoptosis in human colon cancer cells
    126. Efficacy ofSulforaphane in eradicating Helicobacter pylori in human gastric xenografts implanted in nude mice
    127. Delay of photoreceptor degeneration in tubby mouse by Sulforaphane
    128. Sulforaphane regulates self-renewal of pancreatic cancer stem cells through the modulation of Sonic hedgehog–GLI pathway
    129. Evaporative light-scattering analysis of Sulforaphane in broccoli samples: Quality of broccoli products regarding Sulforaphane contents
    130. Chemoprevention of familial adenomatous polyposis by natural dietary compounds Sulforaphane and dibenzoylmethane alone and in combination in ApcMin/+ …
    131. Sulforaphane synergizes with quercetin to inhibit self-renewal capacity of pancreatic cancer stem cells
    132. Sulforaphane activates heat shock response and enhances proteasome activity through up-regulation of Hsp27
    133. Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by Sulforaphane and other electrophiles via an antioxidant response element
    134. Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China
    135. Effect of Sulforaphane on metallothionein expression and induction of apoptosis in human hepatoma HepG2 cells
    136. Sulforaphane enhances the therapeutic potential of TRAIL in prostate cancer orthotopic model through regulation of apoptosis, metastasis, and angiogenesis
    137. Induction of medulloblastoma cell apoptosis by Sulforaphane, a dietary anticarcinogen from Brassica vegetables
    138. Separation by solid phase extraction and quantification by reverse phase HPLC of Sulforaphane in broccoli
    139. Inhibition of human cytochrome P450 enzymes by 1, 2-dithiole-3-thione, oltipraz and its derivatives, and Sulforaphane
    140. Transcriptomic and proteomic profiling of KEAP1 disrupted and Sulforaphane-treated human breast epithelial cells reveals common expression profiles
    141. Cooking method significantly effects glucosinolate content and Sulforaphane production in broccoli florets
    142. Sulforaphane inhibits mitochondrial permeability transition and oxidative stress
    143. Mechanism of action of Sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element …
    144. The role of protein binding in induction of apoptosis by phenethyl isothiocyanate and Sulforaphane in human non–small lung cancer cells
    145. Synergy between Sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation
    146. Sulforaphane-stimulated phase II enzyme induction inhibits cytokine production by airway epithelial cells stimulated with diesel extract
    147. Protective effects of benzyl isothiocyanate and Sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters
    148. Sulforaphane, erucin, and iberin up-regulate thioredoxin reductase 1 expression in human MCF-7 cells
    149. Reprogramming of keratin biosynthesis by Sulforaphane restores skin integrity in epidermolysis bullosa simplex
    150. Sulforaphane, a natural constituent of broccoli, prevents cell death and inflammation in nephropathy
    151. Sulforaphane induces cell cycle arrest and apoptosis in acute lymphoblastic leukemia cells
    152. Nrf2 and NF-κB modulation by Sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes
    153. Development of Sulforaphane-encapsulated microspheres for cancer epigenetic therapy
    154. Sulforaphane attenuates obesity by inhibiting adipogenesis and activating the AMPK pathway in obese mice
    155. Signaling pathways and intracellular targets of Sulforaphane mediating cell cycle arrest and apoptosis
    156. HPLC screening of anti-cancer Sulforaphane from important European Brassica species
    157. Differential effects of Sulforaphane on histone deacetylases, cell cycle arrest and apoptosis in normal prostate cells versus hyperplastic and cancerous prostate cells
    158. Sulforaphane inhibits mitotic clonal expansion during adipogenesis through cell cycle arrest
    159. Sulforaphane, an activator of Nrf2, suppresses cellular accumulation of arsenic and its cytotoxicity in primary mouse hepatocytes
    160. Neuroprotective effects of Sulforaphane after contusive spinal cord injury
    161. Synthesis of (R)‐Sulforaphane Using [cpru(R, R)‐CHIRAPHOS)]+ as Chiral Auxiliary
    162. Immunomodulatory activity of Sulforaphane, a naturally occurring isothiocyanate from broccoli (Brassica oleracea)
    163. Sulforaphane inhibits growth of phenotypically different breast cancer cells
    164. Sulforaphane sensitizes tumor necrosis factor–related apoptosis-inducing ligand (TRAIL)–resistant hepatoma cells to TRAIL-induced apoptosis through reactive …
    165. Preparation and stability investigation of the inclusion complex of Sulforaphane with hydroxypropyl-β-cyclodextrin
    166. Interactions between Sulforaphane and apigenin in the induction of UGT1A1 and GSTA1 in CaCo-2 cells
    167. Bioavailability and inter-conversion of Sulforaphane and erucin in human subjects consuming broccoli sprouts or broccoli supplement in a cross-over study design
    168. Sulforaphane induces inhibition of human umbilical vein endothelial cells proliferation by apoptosis
    169. Combination treatment with resveratrol and Sulforaphane induces apoptosis in human U251 glioma cells
    170. HPLC method validation for measurement of Sulforaphane level in broccoli by‐products
    171. Induction of Quinone Reductase by Sulforaphane and Sulforaphane N-Acetylcysteine Conjugate in Murine Hepatoma Cells
    172. Protection against amyloid beta cytotoxicity by Sulforaphane: role of the proteasome
    173. Sulforaphane composition, cytotoxic and antioxidant activity of crucifer vegetables
    174. Inhibition of benzo [a] pyrene-and 1, 6-dinitropyrene-DNA adduct formation in human mammary epithelial cells bydibenzoylmethane and Sulforaphane
    175. Sulforaphane treatment protects skeletal muscle against damage induced by exhaustive exercise in rats
    176. Sulforaphane and erucin, natural isothiocyanates from broccoli, inhibit bacterial quorum sensing
    177. Nrf2 activation by Sulforaphane restores the age-related decrease of TH1 immunity: Role of dendritic cells
    178. Sonic hedgehog signaling inhibition provides opportunities for targeted therapy by Sulforaphane in regulating pancreatic cancer stem cell self-renewal
    179. Role of increased expression of the proteasome in the protective effects of Sulforaphane against hydrogen peroxide-mediated cytotoxicity in murine neuroblastoma …
    180. Sulforaphane suppresses TNF-α-mediated activation of NF-κB and induces apoptosis through activation of reactive oxygen species-dependent caspase-3
    181. d , l –Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1
    182. Sulforaphane attenuates hepatic fibrosis via NF-E2-related factor 2-mediated inhibition of transforming growth factor-β/Smad signaling
    183. The dietary isothiocyanate Sulforaphane targets pathways of apoptosis, cell cycle arrest, and oxidative stress in human pancreatic cancer cells and inhibits tumor …
    184. Sulforaphane and prostate cancer interception
    185. Sulforaphane preconditioning of the Nrf2/HO-1 defense pathway protects the cerebral vasculature against blood–brain barrier disruption and neurological deficits in …
    186. Sulforaphane as an inducer of glutathione prevents oxidative stress‐induced cell death in a dopaminergic‐like neuroblastoma cell line
    187. Sulforaphane induces cell cycle arrest by protecting RB-E2F-1 complex in epithelial ovarian cancer cells
    188. Sulforaphane generates reactive oxygen species leading to mitochondrial perturbation for apoptosis in human leukemia U937 cells
    189. Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with Sulforaphane
    190. Inhibition of bladder cancer by broccoli isothiocyanates Sulforaphane and erucin: characterization, metabolism, and interconversion
    191. Protective effect of Sulforaphane pretreatment against cisplatin-induced liver and mitochondrial oxidant damage in rats
    192. Sulforaphane and erucin increase MRP1 and MRP2 in human carcinoma cell lines
    193. The dietary histone deacetylase inhibitor Sulforaphane induces human β‐defensin‐2 in intestinal epithelial cells
    194. Minocycline and Sulforaphane inhibited lipopolysaccharide-mediated retinal microglial activation
    195. Sulforaphane induces Nrf2 and protects against CYP2E1-dependent binge alcohol-induced liver steatosis
    196. Food matrix effects on bioactivity of broccoli-derived Sulforaphane in liver and colon of F344 rats
    197. Role of PI3K/Akt and MEK/ERK signaling pathways in Sulforaphane-and erucin-induced phase II enzymes and MRP2 transcription, G2/M arrest and cell death in Caco …
    198. Sulforaphane alleviates scopolamine-induced memory impairment in mice
    199. Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2 (COX-2) expression through the modulation of multiple targets in COX-2 gene promoter
    200. Pharmacogenomics of cancer chemopreventive isothiocyanate compound Sulforaphane in the intestinal polyps of ApcMin/+ mice
    201. Purification of Sulforaphane from Brassica oleracea seed meal using low-pressure column chromatography
    202. Stability and encapsulation efficiency of Sulforaphane microencapsulated by spray drying
    203. Transcription factor Nrf2 mediates an adaptive response to Sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and …
    204. Sulforaphane protects immature hippocampal neurons against death caused by exposure to hemin or to oxygen and glucose deprivation
    205. Sulforaphane ameliorates the development of experimental autoimmune encephalomyelitis by antagonizing oxidative stress and Th17-related inflammation in mice
    206. Suppression of microtubule dynamic instability and turnover in MCF7 breast cancer cells by Sulforaphane
    207. Involvement of c-Jun N-terminal Kinase in G2/M Arrest and Caspase-Mediated Apoptosis Induced by Sulforaphane in DU145 Prostate Cancer Cells
    208. Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and Sulforaphane-rich broccoli sprout beverages in Qidong, China
    209. Synergistic anti-inflammatory effects of nobiletin and Sulforaphane in lipopolysaccharide-stimulated RAW 264.7 cells
    210. Glucoraphanin hydrolysis by microbiota in the rat cecum results in Sulforaphane absorption
    211. Induction of p21 protein protects against Sulforaphane-induced mitotic arrest in LNCaP human prostate cancer cell line
    212. The impaired glutathione system and its up-regulation by Sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats
    213. Repeated intake of broccoli does not lead to higher plasma levels of Sulforaphane in human volunteers
    214. Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to Sulforaphane
    215. Sulforaphane alleviates muscular dystrophy in mdx mice by activation of Nrf2
    216. Temporal changes in gene expression induced by Sulforaphane in human prostate cancer cells
    217. Sulforaphane induces DNA single strand breaks in cultured human cells
    218. Sulforaphane modulates cell cycle and apoptosis in transformed and non‐transformed human T lymphocytes
    219. Requirement and epigenetics reprogramming of Nrf2 in suppression of tumor promoter TPA-induced mouse skin cell transformation by Sulforaphane
    220. Induction of phase 2 antioxidant enzymes by broccoli Sulforaphane: perspectives in maintaining the antioxidant activity of vitamins A, C, and E
    221. Sulforaphane increases the efficacy of doxorubicin in mouse fibroblasts characterized by p53 mutations
    222. Effect of Sulforaphane on cell growth, G0/G1 phase cell progression and apoptosis in human bladder cancer T24 cells
    223. Sulforaphane suppresses polycomb group protein level via a proteasome-dependent mechanism in skin cancer cells
    224. Sulforaphane inhibited expression of hypoxia‐inducible factor‐1α in human tongue squamous cancer cells and prostate cancer cells
    225. Induction of hepatic thioredoxin reductase activity by Sulforaphane, both in Hepa1c1c7 cells and in male Fisher 344 rats
    226. Urease from Helicobacter pylori is inactivated by Sulforaphane and other isothiocyanates
    227. HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with Sulforaphane and related dietary isothiocyanates
    228. Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of Sulforaphane in rats: Implications for its chemopreventive activity
    229. Sulforaphane enhances TRAIL-induced apoptosis through the induction of DR5 expression in human osteosarcoma cells
    230. Factors influencing glucoraphanin and Sulforaphane formation in Brassica plants: a review
    231. p53-independent G1 cell cycle arrest of human colon carcinoma cells HT-29 by Sulforaphane is associated with induction of p21CIP1 and inhibition of expression of …
    232. Sulforaphane–PLGA microspheres for the intra-articular treatment of osteoarthritis
    233. Sulforaphane-rich broccoli sprout extract attenuates nasal allergic response to diesel exhaust particles
    234. Sulforaphane and 2-oxohexyl isothiocyanate induce cell growth arrest and apoptosis in L-1210 leukemia and ME-18 melanoma cells
    235. Sulforaphane restores cellular glutathione levels and reduces chronic periodontitis neutrophil hyperactivity in vitro
    236. Isothiocyanate concentrations and interconversion of Sulforaphane to erucin in human subjects after consumption of commercial frozen broccoli compared to fresh …
    237. Sulforaphane inhibits restenosis by suppressing inflammation and the proliferation of vascular smooth muscle cells
    238. The effect of indole‐3‐carbinol and Sulforaphane on a prostate cancer cell line
    239. Quantitative measurement of Sulforaphane, iberin and their mercapturic acid pathway metabolites in human plasma and urine using liquid chromatography–tandem …
    240. Sulforaphane, quercetin and catechins complement each other in elimination of advanced pancreatic cancer by miR-let-7 induction and K-ras inhibition
    241. Protective effect of Sulforaphane on human vascular endothelial cells against lipopolysaccharide-induced inflammatory damage
    242. Sulforaphane represses matrix‐degrading proteases and protects cartilage from destruction in vitro and in vivo
    243. Targeting cancer stem cells with Sulforaphane, a dietary component from broccoli and broccoli sprouts
    244. Induction of apoptosis by isothiocyanate Sulforaphane in human cervical carcinoma HeLa and hepatocarcinoma HepG2 cells through activation of caspase-3
    245. Repeated transient Sulforaphane stimulation in astrocytes leads to prolonged Nrf2-mediated gene expression and protection from superoxide-induced damage
    246. Effects of Sulforaphane and 3, 3′-diindolylmethane on genome-wide promoter methylation in normal prostate epithelial cells and prostate cancer cells
    247. Quantitative combination effects between Sulforaphane and 3,3′-diindolylmethane on proliferation of human colon cancer cells in vitro
    248. Modulation of experimental herpes encephalitis-associated neurotoxicity through Sulforaphane treatment
    249. Metabolic effects of Sulforaphane oral treatment in streptozotocin-diabetic rats
    250. Sulforaphane attenuates gentamicin-induced nephrotoxicity: role of mitochondrial protection
    251. Attenuation of-amyloid-induced oxidative cell death by Sulforaphane via activation of NF-E2-related factor 2
    252. Stimulation of phagocytosis by Sulforaphane
    253. Modulation of rat pulmonary carcinogen-metabolising enzyme systems by the isothiocyanates erucin and Sulforaphane
    254. Sulforaphane sensitizes tumor necrosis factor-related apoptosis-inducing ligand-mediated apoptosis through downregulation of ERK and Akt in lung adenocarcinoma …
    255. Sulforaphane prevents the development of cardiomyopathy in type 2 diabetic mice probably by reversing oxidative stress-induced inhibition of LKB1/AMPK pathway
    256. Cellular responses to cancer chemopreventive agent D, L-Sulforaphane in human prostate cancer cells are initiated by mitochondrial reactive oxygen species
    257. Sulforaphane inhibits TNF-α-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cells
    258. Epithelial-mesenchymal transition, a novel target of Sulforaphane via COX-2/MMP2, 9/Snail, ZEB1 and miR-200c/ZEB1 pathways in human bladder cancer cells
    259. Sulforaphane but not ascorbigen, indole‐3‐carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase‐2 and antioxidant enzymes in human …
    260. Sulforaphane induced adipolysis via hormone sensitive lipase activation, regulated by AMPK signaling pathway
    261. Sulforaphane induces autophagy through ERK activation in neuronal cells
    262. Anti-tumor activity and signaling events triggered by the isothiocyanates, Sulforaphane and phenethyl isothiocyanate, in multiple myeloma
    263. Stability of Sulforaphane for topical formulation
    264. Sulforaphane inhibits growth of a colon cancer cell line
    265. Sulforaphane halts breast cancer cell growth.
    266. Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells
    267. The inhibition of autophagy potentiates anti-angiogenic effects of Sulforaphane by inducing apoptosis
    268. Antithrombotic activities of Sulforaphane via inhibiting platelet aggregation and FIIa/FXa
    269. Sulforaphane inhibits 4-aminobiphenyl-induced DNA damage in bladder cells and tissues
    270. Inhibition of synovial hyperplasia, rheumatoid T cell activation, and experimental arthritis in mice by Sulforaphane, a naturally occurring isothiocyanate
    271. D, L-Sulforaphane causes transcriptional repression of androgen receptor in human prostate cancer cells
    272. Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells
    273. Administration of the Nrf2–ARE activators Sulforaphane and carnosic acid attenuates 4-hydroxy-2-nonenal-induced mitochondrial dysfunction ex vivo
    274. Sulforaphane can protect lens cells against oxidative stress: implications for cataract prevention
    275. Radiosensitization of head and neck cancer cells by the phytochemical agent Sulforaphane
    276. Epigallocatechin gallate and Sulforaphane combination treatment induce apoptosis in paclitaxel-resistant ovarian cancer cells through hTERT and Bcl-2 down …
    277. Potential health benefits of Sulforaphane: a review of the experimental, clinical and epidemiological evidences and underlying mechanisms
    278. Interaction of the isothiocyanate Sulforaphane with drug disposition and metabolism: pharmacological and toxicological implications
    279. Potent induction of total cellular and mitochondrial antioxidants and phase 2 enzymes by cruciferous Sulforaphane in rat aortic smooth muscle cells: cytoprotection …
    280. Sulforaphane prevents pulmonary damage in response to inhaled arsenic by activating the Nrf2-defense response
    281. Enhanced Nrf2-dependent induction of glutathione in mouse embryonic fibroblasts by isoselenocyanate analog of Sulforaphane
    282. Histone deacetylase turnover and recovery in Sulforaphane-treated colon cancer cells: competing actions of 14-3-3 and Pin1 in HDAC3/SMRT corepressor …
    283. Impact of Thermal Processing on Sulforaphane Yield from Broccoli (Brassica oleracea L. ssp. italica)
    284. … in vitro cell-transforming and DNA-damaging activities by glucoraphanin, the bioprecursor of the chemopreventive agent Sulforaphane found in broccoli
    285. Selenium and Sulforaphane modify the expression of selenoenzymes in the human endothelial cell line EAhy926 and protect cells from oxidative damage
    286. Phase II enzyme inducer, Sulforaphane, inhibits UVB‐induced AP‐1 activation in human keratinocytes by a novel mechanism
    287. Sulforaphane enhances proteasomal and autophagic activities in mice and is a potential therapeutic reagent for Huntington’s disease
    288. Sulforaphane: from chemoprevention to pancreatic cancer treatment?
    289. … -2 and selenium decreased inflammation and tumors in a mouse model of inflammation-associated carcinogenesis whereas Sulforaphane effects differed with …
    290. The indirect antioxidant Sulforaphane protects against thiopurine-mediated photooxidative stress
    291. Analysis and anti-Helicobacter activity of Sulforaphane and related compounds present in broccoli (Brassica oleracea L.) sprouts
    292. Sulforaphane prevention of diabetes-induced aortic damage was associated with the up-regulation of Nrf2 and its down-stream antioxidants
    293. Anticancer activity of a broccoli derivative, Sulforaphane, in barrett adenocarcinoma: potential use in chemoprevention and as adjuvant in chemotherapy
    294. Sulforaphane Inhibits Osteoclastogenesis by Inhibiting Nuclear Factor-κB.
    295. Preparation of (R)-Sulforaphane by biotransformation using Helminthosporium species NRRL 4671
    296. Sulforaphane-a-key-chemopreventive-ingredient-in-broccoli-implications-for-cancer-prevention/632B634A8D2C8165AC0B9959F8CD5302″ target=”_blank” rel=”noopener” data-saferedirecturl=”https://www.google.com/url?hl=en&q=https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/organspecific-exposure-and-response-to-Sulforaphane-a-key-chemopreventive-ingredient-in-broccoli-implications-for-cancer-prevention/632B634A8D2C8165AC0B9959F8CD5302&source=gmail&ust=1579108247854000&usg=AFQjCNExPYrOWraYGEQgg0E_ca6UqSR-Yw”>Organ-specific exposure and response to Sulforaphane, a key chemopreventive ingredient in broccoli: implications for cancer prevention
    297. Sulforaphane protects Microcystin-LR-induced toxicity through activation of the Nrf2-mediated defensive response
    298. Sulforaphane inhibits constitutive and Interleukin-6–induced activation of Signal Transducer and Activator of Transcription 3 in prostate cancer cells
    299. Sulforaphane suppresses ultraviolet B-induced inflammation in HaCaT keratinocytes and HR-1 hairless mice
    300. Time-dependent modulation of thioredoxin reductase activity might contribute to Sulforaphane-mediated inhibition of NF-κB binding to DNA
    301. Sulforaphane induces antioxidative and antiproliferative responses by generating reactive oxygen species in human bronchial epithelial BEAS-2B cells
    302. … oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in Sulforaphane-treated human mesothelioma …
    303. Synthesis of 14C‐labelled Sulforaphane
    304. Sulforaphane protects human chondrocytes against cell death induced by various stimuli
    305. Sulforaphane induces cell cycle arrest and apoptosis in murine osteosarcoma cells in vitro and inhibits tumor growth in vivo
    306. Chemoprevention of cancerogenesis-the role of Sulforaphane
    307. Relevance of anti-inflammatory and antioxidant activities of exemestane and synergism with Sulforaphane for disease prevention
    308. The influence of Sulforaphane on vascular health and its relevance to nutritional approaches to prevent cardiovascular disease
    309. Sulforaphane absorption and excretion following ingestion of a semi-purified broccoli powder rich in glucoraphanin and broccoli sprouts in healthy men
    310. Cyclin D3 and p53 mediate Sulforaphane-induced cell cycle delay and apoptosis in non-transformed human T lymphocytes
    311. Commercially produced frozen broccoli lacks the ability to form Sulforaphane
    312. Induction of apoptosis by Sulforaphane in highly metastatic B16F-10 melanoma cells
    313. Sulforaphane prevents microcystin-LR-induced oxidative damage and apoptosis in BALB/c mice
    314. Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene
    315. Regulation of estrogen receptor α expression in human breast cancer cells by Sulforaphane
    316. Sulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cells
    317. Hydrogen sulfide mediates the anti-survival effect of Sulforaphane on human prostate cancer cells
    318. Sulforaphane protects cortical neurons against 5‐S‐cysteinyl‐dopamine‐induced toxicity through the activation of ERK1/2, Nrf‐2 and the upregulation of …
    319. Chemoprevention of pancreatic cancer using solid-lipid nanoparticulate delivery of a novel aspirin, curcumin and Sulforaphane drug combination regimen
    320. Differential modulation of keratin expression by Sulforaphane occurs via Nrf2-dependent and-independent pathways in skin epithelia
    321. Activation of several concurrent proapoptic pathways by Sulforaphane in human colon cancer cells SW620
    322. Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes
    323. Brain mitochondria from rats treated with Sulforaphane are resistant to redox-regulated permeability transition
    324. Sulforaphane decreases viability and telomerase activity in hepatocellular carcinoma Hep3B cells through the reactive oxygen species-dependent pathway
    325. Repeated Nrf2 stimulation using Sulforaphane protects fibroblasts from ionizing radiation
    326. DSS-induced acute colitis in C57BL/6 mice is mitigated by Sulforaphane pre-treatment
    327. Sulforaphane inhibits the Th2 immune response in ovalbumin-induced asthma
    328. Sulforaphane counteracts aggressiveness of pancreatic cancer driven by dysregulated Cx43-mediated gap junctional intercellular communication
    329. Sulforaphane-and phenethyl isothiocyanate–induced inhibition of aflatoxin B1–mediated genotoxicity in human hepatocytes: Role of GSTM1 genotype and CYP3A4 …
    330. Comparison of the effects of phenethyl isothiocyanate and Sulforaphane on gene expression in breast cancer and normal mammary epithelial cells
    331. Modulation of mitochondrial functions by the indirect antioxidant Sulforaphane: a seemingly contradictory dual role and an integrative hypothesis
    332. Inhibition of activator protein-1 by Sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced …
    333. Sulforaphane down-regulates COX-2 expression by activating p38 and inhibiting NF-κB-DNA-binding activity in human bladder T24 cells
    334. Sulforaphane inhibited melanin synthesis by regulating tyrosinase gene expression in B16 mouse melanoma cells
    335. Sulforaphane attenuation of type 2 diabetes-induced aortic damage was associated with the upregulation of Nrf2 expression and function
    336. Sulforaphane inhibits pancreatic cancer through disrupting Hsp90–p50Cdc37 complex and direct interactions with amino acids residues of Hsp90
    337. Effects of metal ions on myrosinase activity and the formation of Sulforaphane in broccoli seed
    338. Effects of the Sulforaphane analog compound 30, indole-3-carbinol, D-limonene or relafen on glutathione S-transferases and glutathione peroxidase of the rat …
    339. The dietary isothiocyanate Sulforaphane modulates gene expression and alternative gene splicing in a PTEN null preclinical murine model of prostate cancer
    340. … breaks by N-nitrosodimethylamine and 2-amino-3-methylimidazo [4, 5-f] quinoline in THLE cells expressing human CYP isoenzymes and inhibition by Sulforaphane
    341. Sulforaphane-induced apoptosis involves p53 and p38 in melanoma cells
    342. Sulforaphane causes a major epigenetic repression of myostatin in porcine satellite cells
    343. Glucoraphanin, the bioprecursor of the widely extolled chemopreventive agent Sulforaphane found in broccoli, induces phase-I xenobiotic metabolizing enzymes and …
    344. Mechanisms of anticancer activity of Sulforaphane from Brassica oleracea in HEp-2 human epithelial carcinoma cell line
    345. Sulforaphane induces growth arrest and apoptosis in human ovarian cancer cells
    346. Chemopreventive agent Sulforaphane enhances radiosensitivity in human tumor cells
    347. Quantification of Sulforaphane mercapturic acid pathway conjugates in human urine by high-performance liquid chromatography and isotope-dilution tandem mass …
    348. Part of the series: from dietary antioxidants to regulators in cellular signaling and gene regulation: Sulforaphane and selenium, partners in adaptive response and …
    349. Sulforaphane induces CYP1A1 mRNA, protein, and catalytic activity levels via an AhR-dependent pathway in murine hepatoma Hepa 1c1c7 and human HepG2 cells
    350. Sulforaphane protects rodent retinas against ischemia-reperfusion injury through the activation of the Nrf2/HO-1 antioxidant pathway
    351. Sulforaphane and α-Lipoic Acid Upregulate the Expression of the π Class of Glutathione S-Transferase through c-Jun and Nrf2 Activation
    352. The molecular mechanism of action of aspirin, curcumin and Sulforaphane combinations in the chemoprevention of pancreatic cancer
    353. Chemoprevention of prostate cancer by d, l-Sulforaphane is augmented by pharmacological inhibition of autophagy
    354. Serotonin receptors, novel targets of Sulforaphane identified by proteomic analysis in Caco-2 cells
    355. Separation and purification of Sulforaphane from broccoli by solid phase extraction
    356. Synergistic effects of a combination of dietary factors Sulforaphane and (−) epigallocatechin-3-gallate in HT-29 AP-1 human colon carcinoma cells
    357. Sulforaphane induces reactive oxygen species-mediated mitotic arrest and subsequent apoptosis in human bladder cancer 5637 cells
    358. Autophagy and cell death signaling following dietary Sulforaphane act independently of each other and require oxidative stress in pancreatic cancer
    359. Sulforaphane protects against ethanol‐induced oxidative stress and apoptosis in neural crest cells by the induction of N rf2‐mediated antioxidant response
    360. Separation and purification of Sulforaphane from broccoli seeds by solid phase extraction and preparative high-performance liquid chromatography
    361. Sulforaphane Protects from T Cell–Mediated Autoimmune Disease by Inhibition of IL-23 and IL-12 in Dendritic Cells
    362. Chemopreventive functions of Sulforaphane: a potent inducer of antioxidant enzymes and apoptosis
    363. Protective effects of an extract of young radish (Raphanus sativus L) cultivated with sulfur (sulfur-radish extract) and of Sulforaphane on carbon tetrachloride-induced …
    364. Dual action of Sulforaphane in the regulation of thioredoxin reductase and thioredoxin in human HepG2 and Caco-2 cells
    365. Sulforaphane reverses glucocorticoid-induced apoptosis in osteoblastic cells through regulation of the Nrf2 pathway
    366. Effect of Sulforaphane on micronucleus induction in cultured human lymphocytes by four different mutagens
    367. Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner
    368. Sulforaphane decreases endothelial cell apoptosis in fuchs endothelial corneal dystrophy: a novel treatment
    369. … the nuclear factor E2–related factor 2 (Nrf2)–antioxidant-response element (ARE) pathway is essential for neuroprotective effects of Sulforaphane and 6-(methylsulfinyl …
    370. Neuroprotective effects of Sulforaphane on cholinergic neurons in mice with Alzheimer’s disease-like lesions
    371. Role of Lipid Peroxidation in Cellular Responses to d,l-Sulforaphane, a Promising Cancer Chemopreventive Agent
    372. Combination of Doxorubicin and Sulforaphane for Reversing Doxorubicin‐Resistant Phenotype in Mouse Fibroblasts with p53Ser220 Mutation
    373. Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB …
    374. Sulforaphane induces oxidative stress and death by p53-independent mechanism: implication of impaired glutathione recycling
    375. Sulforaphane Inhibits Oral Carcinoma Cell Migration and Invasion In Vitro
    376. Sulforaphane induced cell cycle arrest in the G2/M phase via the blockade of cyclin B1/CDC2 in human ovarian cancer cells
    377. Sulforaphane inhibits the engagement of LPS with TLR4/MD2 complex by preferential binding to Cys133 in MD2
    378. … -mediated apoptosis in ovarian cancer cells through potentiating G2/M arrest and p21 upregulation by combinatorial epigallocatechin gallate and Sulforaphane
    379. The potential to intensify Sulforaphane formation in cooked broccoli (Brassica oleracea var. italica) using mustard seeds (Sinapis alba)
    380. Concurrent Sulforaphane and eugenol induces differential effects on human cervical cancer cells
    381. Protective effects of the antioxidant Sulforaphane on behavioral changes and neurotoxicity in mice after the administration of methamphetamine
    382. Isothiocyanate metabolism, distribution, and interconversion in mice following consumption of thermally processed broccoli sprouts or purified Sulforaphane
    383. Photothrombosis-induced infarction of the mouse cerebral cortex is not affected by the Nrf2-activator Sulforaphane
    384. Sulforaphane-induced autophagy flux prevents prion protein-mediated neurotoxicity through AMPK pathway
    385. Sulforaphane reduction of testicular apoptotic cell death in diabetic mice is associated with the upregulation of Nrf2 expression and function
    386. Modulation of cell-mediated immune response in B16F-10 melanoma-induced metastatic tumor-bearing C57BL/6 mice by Sulforaphane
    387. Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, Sulforaphane
    388. Sulforaphane and related mustard oils in focus of cancer prevention and therapy
    389. Anti-carcinogenic effects of Sulforaphane in association with its apoptosis-inducing and anti-inflammatory properties in human cervical cancer cells
    390. Pretreatment of human epidermal keratinocytes with D, L-Sulforaphane protects against sulfur mustard cytotoxicity
    391. Sulforaphane induces cytotoxicity and lysosome-and mitochondria-dependent cell death in colon cancer cells with deleted p53
    392. D,L‐Sulforaphane‐induced apoptosis in human breast cancer cells is regulated by the adapter protein p66Shc
    393. Effects of the antioxidant Sulforaphane on hyperlocomotion and prepulse inhibition deficits in mice after phencyclidine administration
    394. Sulforaphane induces G2–M arrest and apoptosis in high metastasis cell line of salivary gland adenoid cystic carcinoma
    395. Sulforaphane controls TPA-induced MMP-9 expression through the NF-κB signaling pathway, but not AP-1, in MCF-7 breast cancer cells
    396. Kinetics of Sulforaphane in mice after consumption of Sulforaphane‐enriched broccoli sprout preparation
    397. Comparison of the apoptosis-inducing capability of Sulforaphane analogues in human colon cancer cells
    398. Simultaneous determination of Sulforaphane and its major metabolites from biological matrices with liquid chromatography–tandem mass spectroscopy
    399. Sulforaphane potentiates the efficacy of imatinib against chronic leukemia cancer stem cells through enhanced abrogation of Wnt/β-catenin function
    400. Sulforaphane suppresses vascular adhesion molecule-1 expression in TNF-α-stimulated mouse vascular smooth muscle cells: involvement of the MAPK, NF-κB and …
    401. The phase 2 enzyme inducers ethacrynic acid, DL-Sulforaphane, and oltipraz inhibit lipopolysaccharide-induced high-mobility group box 1 secretion by RAW 264.7 …
    402. The dietary phase 2 protein inducer