Sulforaphane
January 15, 2020
Ursolic Acid
January 15, 2020
Thymoquinone
- Thymoquinone is a potent superoxide anion scavenger
- Hepatoprotective activity of Thymoquinone in isolated rat hepatocytes
- Thymoquinone: potential cure for inflammatory disorders and cancer
- Thymoquinone: a promising anti-cancer drug from natural sources
- Fixed oil of Nigella sativa and derived Thymoquinone inhibit eicosanoid generation in leukocytes and membrane lipid peroxidation
- The influence of Thymoquinone on doxorubicin-induced hyperlipidemic nephropathy in rats
- Thymoquinone and its therapeutic potentials
- Thymoquinone protects against carbon tetrachloride hetatotoxicity in mice via an antioxidant mechanism
- Inhibitory effects of Thymoquinone against 20-methylcholanthrene-induced fibrosarcoma tumorigenesis.
- In vitro toxicological properties of Thymoquinone
- Antinociceptive effects of Nigella sativa oil and its major component, Thymoquinone, in mice
- Effects of Thymoquinone (volatile oil of black cumin) on rheumatoid arthritis in rat models
- Thymoquinone protects against experimental colitis in rats
- Anticonvulsant effects of Thymoquinone, the major constituent of Nigella sativa seeds, in mice
- Antitumor activity of gemcitabine and oxaliplatin is augmented by Thymoquinone in pancreatic cancer
- Acute and subchronic toxicity of Thymoquinone in mice
- Thymoquinone protects against doxorubicin-induced cardiotoxicity without compromising its antitumor activity.
- Inhibition of benzo (a) pyrene-induced forestomach carcinogenesis in mice by Thymoquinone.
- In Vitro acetylcholinesterase inhibitory properties of thymol, carvacrol and their derivatives Thymoquinone and thymohydroquinone
- Review on molecular and therapeutic potential of Thymoquinone in cancer
- Oral and intraperitoneal LD50 of Thymoquinone, an active principle of Nigella sativa, in mice and rats
- Improvement of experimental allergic encephalomyelitis (EAE) by Thymoquinone; an oxidative stress inhibitor.
- Thymoquinone reduces hepatic glucose production in diabetic hamsters
- In vitro inhibition of growth and induction of apoptosis in cancer cell lines by Thymoquinone
- Thymoquinone suppresses expression of inducible nitric oxide synthase in rat macrophages
- Androgen receptor–and E2F-1–targeted Thymoquinone therapy for hormone-refractory prostate cancer
- Thymoquinone inhibits tumor angiogenesis and tumor growth through suppressing AKT and extracellular signal-regulated kinase signaling pathways
- Neuroprotective effects of Thymoquinone against transient forebrain ischemia in the rat hippocampus
- Anti-inflammatory effect of Thymoquinone in a mouse model of allergic lung inflammation
- Protective effects of Thymoquinone and desferrioxamine against hepatotoxicity of carbon tetrachloride in mice
- Thymoquinone ameliorates the nephrotoxicity induced by cisplatin in rodents and potentiates its antitumor activity
- Thymoquinone-in-rats/” target=”_blank” rel=”noopener” data-saferedirecturl=”https://www.google.com/url?hl=en&q=https://vlibrary.emro.who.int/imemr/a-study-of-the-anti-inflammatory-activity-of-nigella-sativa-l-and-Thymoquinone-in-rats/&source=gmail&ust=1578765043452000&usg=AFQjCNEz35n-wi7Hac9DaSgvN3Tu5YC5bA”>Study of the anti-inflammatory activity of Nigella sativa L and Thymoquinone in rats, Saudi Pharm
- Anti-inflammatory effects of the Nigella sativa seed extract, Thymoquinone, in pancreatic cancer cells
- Antidermatophyte activity of ether extract of Nigella sativa and its active principle, Thymoquinone
- Thymoquinone extracted from black seed triggers apoptotic cell death in human colorectal cancer cells via a p53-dependent mechanism
- Reactive oxygen species mediate Thymoquinone-induced apoptosis and activate ERK and JNK signaling
- Nigella sativa oil, nigellone and derived Thymoquinone inhibit synthesis of 5-lipoxygenase products in polymorphonuclear leukocytes from rats
- Thymoquinone attenuates diethylnitrosamine induction of hepatic carcinogenesis through antioxidant signaling
- Effects of alpha-hederin and Thymoquinone, constituents of Nigella sativa, on human cancer cell lines
- Nonenzymatic reduction of Thymoquinone in physiological conditions
- Thymoquinone attenuates ifosfamide-induced Fanconi syndrome in rats and enhances its antitumor activity in mice
- Lack of p53 augments Thymoquinone-induced apoptosis and caspase activation in human osteosarcoma cells
- Targeting nuclear factor-κB activation pathway by Thymoquinone: role in suppression of antiapoptotic gene products and enhancement of apoptosis
- Thymoquinone: fifty years of success in the battle against cancer models
- Anticancer activity of Thymoquinone in breast cancer cells: possible involvement of PPAR-γ pathway
- Antibacterial activity of Thymoquinone, an active principle of Nigella sativa and its potency to prevent bacterial biofilm formation
- Thymoquinone supplementation prevents the development of gentamicin‐induced acute renal toxicity in rats
- Thymoquinone induces apoptosis through activation of caspase‐8 and mitochondrial events in p53‐null myeloblastic leukemia HL‐60 cells
- The effect of Thymoquinone on blood lipids in rats
- Thymoquinone supplementation attenuates hypertension and renal damage in nitric oxide deficient hypertensive rats
- Beneficial effects of Thymoquinone on hepatic key enzymes in streptozotocin–nicotinamide induced diabetic rats
- Effects of Thymoquinone on antioxidant enzyme activities, lipid peroxidation and DT‐diaphorase in different tissues of mice: a possible mechanism of action
- Effect of Thymoquinone and Nigella sativa seeds oil on lipid peroxidation level during global cerebral ischemia-reperfusion injury in rat hippocampus
- Protective effects of propolis and Thymoquinone on development of atherosclerosis in cholesterol-fed rabbits
- Nigella sativa Thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats
- Thymoquinone protects dopaminergic neurons against MPP+ and rotenone
- Thymoquinone and cisplatin as a therapeutic combination in lung cancer: In vitro and in vivo
- Gastroprotective activity of Nigella sativa L oil and its constituent, Thymoquinone against acute alcohol-induced gastric mucosal injury in rats
- The effect of Thymoquinone on intractable pediatric seizures (pilot study)
- Gastroprotective activity of Nigella sativa oil and its constituent, Thymoquinone, against gastric mucosal injury induced by ischaemia/reperfusion in rats
- Thymoquinone supplementation attenuates cyclophosphamide‐induced cardiotoxicity in rats
- Thymoquinone: Novel gastroprotective mechanisms
- Thymoquinone induces telomere shortening, DNA damage and apoptosis in human glioblastoma cells
- Protective effects of Thymoquinone against methotrexate-induced testicular injury
- Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells
- The protective effect of Thymoquinone, an anti-oxidant and anti-inflammatory agent, against renal injury: a review
- RETRACTED: Thymoquinone poly (lactide-co-glycolide) nanoparticles exhibit enhanced anti-proliferative, anti-inflammatory, and chemosensitization potential
- The antioxidative and antihistaminic effect of Nigella sativa and its major constituent, Thymoquinone on ethanol-induced gastric mucosal damage
- The antitumor activity of Thymoquinone and thymohydroquinone in vitro and in vivo
- Combinatorial effects of Thymoquinone on the anti-cancer activity of doxorubicin
- Inhibition of 5-lipoxygenase and Leukotriene C4 Synthase in Human Blood Cells by Thymoquinone
- Neuroprotection with metformin and Thymoquinone against ethanol-induced apoptotic neurodegeneration in prenatal rat cortical neurons
- Thymoquinone and Nigella sativa oil protection against methionine-induced hyperhomocysteinemia in rats
- Nigella sativa and Derived Thymoquinone Prevents Hippocampal Neurodegeneration After Chronic Toluene Exposure in Rats
- Fatty acid profile, Thymoquinone content, oxidative stability, and antioxidant properties of cold-pressed black cumin seed oils
- Antibacterial activity of Thymoquinone and thymohydroquinone of Nigella sativa L. and their interaction with some antibiotics
- Thymoquinone protects cultured rat primary neurons against amyloid β-induced neurotoxicity
- Anticlastogenic activity of Thymoquinone against benzo (a) pyrene in mice
- Modulation of the oxidative stress and inflammatory cytokine response by Thymoquinone in the collagen induced arthritis in Wistar rats
- Elucidation of molecular mechanisms underlying the protective effects of Thymoquinone against rheumatoid arthritis
- Thymoquinone in the clinical treatment of cancer: Fact or fiction?
- Thymoquinone reduces mouse colon tumor cell invasion and inhibits tumor growth in murine colon cancer models
- Effect of Thymoquinone on cyclooxygenase expression and prostaglandin production in a mouse model of allergic airway inflammation
- Effects of Nigella sativa and its Major Constituent, Thymoquinone on Sciatic Nerves in Experimental Diabetic Neuropathy
- Black cumin (Nigella sativa) and its constituent (Thymoquinone): a review on antimicrobial effects
- Protective effects of Nigella sativa oil and Thymoquinone against toxicity induced by the anticancer drug cyclophosphamide
- The protective effect of Thymoquinone on ethanol-induced acute gastric damage in the rat
- Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome
- Thymoquinone in liposomes: a study of loading efficiency and biological activity towards breast cancer
- Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells
- Thymoquinone-induced relaxation of guinea-pig isolated trachea.
- Protective effects of Thymoquinone on streptozotocin-induced diabetic nephropathy
- Effect of Nigella Sativa (Black Seed) and Thymoquinone on Blood Glucose in Albino Rats
- Intracerebroventricular administration of Thymoquinone, the major constituent of Nigella sativa seeds, suppresses epileptic seizures in rats.
- Thymoquinone treatment against acetaminophen-induced hepatotoxicity in rats
- Antitumor and anti-angiogenesis effects of Thymoquinone on osteosarcoma through the NF-κB pathway
- Effects of Nigella sativa and Thymoquinone on biochemical and subcellular changes in pancreatic β‐cells of streptozotocin‐induced diabetic rats
- Effects of borneol and Thymoquinone on TNBS-induced colitis in mice
- Antineoplastic and apoptotic potential of traditional medicines Thymoquinone and diosgenin in squamous cell carcinoma
- Development and evaluation of Thymoquinone-encapsulated chitosan nanoparticles for nose-to-brain targeting: a pharmacoscintigraphic study
- Structure-activity studies on therapeutic potential of Thymoquinone analogs in pancreatic cancer
- Thymoquinone attenuates cisplatin-induced hepatotoxicity via nuclear factor kappa-β
- Thymoquinone produced antianxiety-like effects in mice through modulation of GABA and NO levels
- Effects of Nigella sativa oil and Thymoquinone on oxidative stress and neuropathy in streptozotocin-induced diabetic rats
- Thymoquinone supplementation reverses acetaminophen-induced oxidative stress, nitric oxide production and energy decline in mice liver
- TLC Assay of Thymoquinone in Black Seed Oil (Nigella Sativa Linn) and Identification of DiThymoquinone and Thymol
- Thymoquinone inhibits the activation of NF-kappaB in the brain and spinal cord of experimental autoimmune encephalomyelitis.
- Targeted apoptotic effects of Thymoquinone and tamoxifen on XIAP mediated Akt regulation in breast cancer
- Cytogenetic studies on Nigella sativa seeds extract and Thymoquinone on mouse cells infected with schistosomiasis using karyotyping
- Chemical composition, antimicrobial potential against cariogenic bacteria and cytotoxic activity of Tunisian Nigella sativa essential oil and Thymoquinone
- Thymoquinone ameliorates chemical induced oxidative stress and β-cell damage in experimental hyperglycemic rats
- Thymoquinone ameliorates renal oxidative damage and proliferative response induced by mercuric chloride in rats
- Modes of action of alpha-hederin and Thymoquinone, active constituents of Nigella sativa, against HEp-2 cancer cells
- Thymoquinone attenuates liver fibrosis via PI3K and TLR4 signaling pathways in activated hepatic stellate cells
- Thymoquinone induces mitochondria-mediated apoptosis in acute lymphoblastic leukaemia in vitro
- Cadmium‐induced hepatotoxicity and its abrogation by Thymoquinone
- Thymoquinone supplementation induces quinone reductase and glutathione transferase in mice liver: possible role in protection against chemical carcinogenesis and …
- Protective Effect of Nigella sativa Extract and Thymoquinone on Serum/Glucose Deprivation-Induced PC12 Cells Death
- Protective effect of Thymoquinone in experimental testicular torsion
- Studies on molecular mechanisms of growth inhibitory effects of Thymoquinone against prostate cancer cells: role of reactive oxygen species
- Successful abrogation by Thymoquinone against induction of diabetes mellitus with streptozotocin via nitric oxide inhibitory mechanism
- Thymoquinone attenuates proinflammatory responses in lipopolysaccharide-activated mast cells by modulating NF-kappaB nuclear transactivation
- Comparison of potential chemotherapeutic agents, 5-fluoruracil, green tea, and Thymoquinone on colon cancer cells.
- Thymoquinone and proanthocyanidin attenuation of diabetic nephropathy in rats
- Protective effect of pretreatment with Thymoquinone against Aflatoxin B1 induced liver toxicity in mice
- Mechanisms of Thymoquinone hepatorenal protection in methotrexate-induced toxicity in rats
- Thymoquinone: an emerging natural drug with a wide range of medical applications
- A simple and efficient synthesis of Thymoquinone and methyl p-benzoquinone
- Terpene Conjugates of the Nigella sativa Seed‐Oil Constituent Thymoquinone with Enhanced Efficacy in Cancer Cells
- Thymoquinone inhibits proliferation, induces apoptosis and chemosensitizes human multiple myeloma cells through suppression of signal transducer and activator of …
- Thymoquinone from Eupatorium ayapana
- HIV-1 protease inhibitor induced oxidative stress suppresses glucose stimulated insulin release: protection with Thymoquinone
- Preclinical and clinical effects of Nigella sativa and its constituent, Thymoquinone: A review
- Downregulation of leukotriene biosynthesis by Thymoquinone attenuates airway inflammation in a mouse model of allergic asthma
- Thymoquinone inhibits autophagy and induces cathepsin-mediated, caspase-independent cell death in glioblastoma cells
- Phase I safety and clinical activity study of Thymoquinone in patients with advanced refractory malignant disease
- Protective effects of Thymoquinone on vancomycin-induced nephrotoxicity in rats
- Thymoquinone inhibits growth and augments 5-fluorouracil-induced apoptosis in gastric cancer cells both in vitro and in vivo
- Effect of Thymoquinone on mouse dendritic cells
- Levels of selenium, dl-α-tocopherol, dl-γ-tocopherol, all-trans-retinol, Thymoquinone and thymol in different brands of Nigella sativa seeds
- Thymoquinone decreases AGE‐induced NF‐κB activation in proximal tubular epithelial cells
- Anti-cancer properties of Nigella spp. essential oils and their major constituents, Thymoquinone and β-elemene
- Thymoquinone ameliorates lead-induced brain damage in Sprague Dawley rats
- Anti-metastasis effect of Thymoquinone on human pancreatic cancer
- Antibacterial and resistance-modifying activities of Thymoquinone against oral pathogens
- The protective effect of Thymoquinone against sepsis syndrome morbidity and mortality in mice
- Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma
- Is Thymoquinone an antioxidant?
- Thymoquinone attenuates Doxorubicin-induced nephrotoxicity in rats: Role of Nrf2 and NOX4
- Immunomodulatory and anti-inflammatory action of Nigella sativa and Thymoquinone: A comprehensive review
- Attenuation of Aβ-induced neurotoxicity by Thymoquinone via inhibition of mitochondrial dysfunction and oxidative stress
- Effects of Thymoquinone in the expression of mucin 4 in pancreatic cancer cells: implications for the development of novel cancer therapies
- Contrasting actions of diesel exhaust particles on the pulmonary and cardiovascular systems and the effects of Thymoquinone
- Thymoquinone as an anticancer agent: evidence from inhibition of cancer cells viability and invasion in vitro and tumor growth in vivo
- Induction of apoptosis by Thymoquinone in lymphoblastic leukemia Jurkat cells is mediated by a p73-dependent pathway which targets the epigenetic integrator …
- Nanocarrier based formulation of Thymoquinone improves oral delivery: stability assessment, in vitro and in vivo studies
- In search of novel highly active mitochondria‐targeted antioxidants: Thymoquinone and its cationic derivatives
- Regulation of renal organic anion and cation transporters by Thymoquinone in cisplatin induced kidney injury
- Inhibitory effects of topical Thymoquinone on corneal neovascularization
- Thymoquinone alleviates thioacetamide-induced hepatic fibrosis and inflammation by activating LKB1–AMPK signaling pathway in mice
- Thymoquinone-induced suicidal erythrocyte death
- Black cumin (Nigella sativa) and its active constituent, Thymoquinone: an overview on the analgesic and anti-inflammatory effects
- Effect of Thymoquinone on ethylene glycol-induced kidney calculi in rats
- Effect of Thymoquinone on the lung pathology and cytokine levels of ovalbumin-sensitized guinea pigs
- Synergism from combinations of cisplatin and oxaliplatin with quercetin and Thymoquinone in human ovarian tumour models
- Thymoquinone accelerates new bone formation in the rapid maxillary expansion procedure
- Comparative evaluation of anti-inflammatory properties of Thymoquinone and curcumin using an asthmatic murine model
- Anti-fibrotic effect of Thymoquinone on hepatic stellate cells
- Effects of (-) epigallocatechin gallate and Thymoquinone on proliferation of a PANC-1 cell line in culture.
- Neuroprotective effect of Thymoquinone in acrylamide-induced neurotoxicity in Wistar rats
- Effects of Thymoquinone on isolated and cellular proteasomes
- Thymoquinone protects renal tubular cells against tubular injury
- Thymoquinone ameliorates the immunological and histological changes induced by exposure to imidacloprid insecticide
- Mechanistic perspectives on cancer chemoprevention/
chemotherapeutic effects of Thymoquinone - The effect of route of administration in Thymoquinone toxicity in male and female rats
- Thymoquinone inhibits tumor growth and induces apoptosis in a breast cancer xenograft mouse model: the role of p38 MAPK and ROS
- Neuroprotective effect of Thymoquinone, the nigella sativa bioactive compound, in 6-hydroxydopamine-induced hemi-parkinsonian rat model
- Antitussive effect of Thymoquinone, a constituent of Nigella sativa seeds, in guinea pigs
- Radiosensitization in human breast carcinoma cells by Thymoquinone: role of cell cycle and apoptosis
- Macrophage-derived cytokine and nitric oxide profiles in type I and type II diabetes mellitus: effect of Thymoquinone
- Hypolipidemic and antioxidant activities of Thymoquinone and limonene in atherogenic suspension fed rats
- Simple HPLC method for the determination of Thymoquinone in black seed oil (Nigella sativa Linn)
- Perinatal supplementation with Thymoquinone improves diabetic complications and T cell immune responses in rat offspring
- Effect of Thymoquinone on malformations and oxidative stress-induced diabetic mice
- Protective effect of Thymoquinone against cisplatin-induced ototoxicity
- The effect of Thymoquinone, the main constituent of Nigella sativa on tracheal responsiveness and white blood cell count in lung lavage of sensitized guinea pigs
- Protective effect of Thymoquinone on sodium fluoride-induced hepatotoxicity and oxidative stress in rats
- Inhibition of the formation of advanced glycation end products by Thymoquinone
- Leishmanicidal and cytotoxic activities of Nigella sativa and its active principle, Thymoquinone
- Delivery of phytochemical Thymoquinone using molecular micelle modified poly (D, L lactide-co-glycolide)(PLGA) nanoparticles
- Molecular targeting of Akt by Thymoquinone promotes G1 arrest through translation inhibition of cyclin D1 and induces apoptosis in breast cancer cells
- Structural and vibrational analysis of Thymoquinone
- Thymoquinone-loaded nanostructured lipid carriers: preparation, gastroprotection, in vitro toxicity, and pharmacokinetic properties after extravascular …
- Therapeutic potential of Thymoquinone against anti-tuberculosis drugs induced liver damage
- Thymoquinone regulates gene expression levels in the estrogen metabolic and interferon pathways in MCF7 breast cancer cells
- Thymoquinone prevents and ameliorates dextran sulfate sodium-induced colitis in mice
- Anti-inflammatory effects of Thymoquinone in activated BV-2 microglial cells
- Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition
- Anti-inflammatory Effect of Seeds and Callus of Nigella sativa L. Extracts on Mix Glial Cells with Regard to Their Thymoquinone Content
- Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein
- Thymoquinone attenuates cyclophosphamide-induced pulmonary injury in rats
- Preventive effects of Thymoquinone in a rat periodontitis model: a morphometric and histopathological study
- Investigation of antioxidant synergisms and antagonisms among thymol, carvacrol, Thymoquinone and p-cymene in a model system using the Briggs–Rauscher …
- A comparison of 5-fluorouracil and natural chemotherapeutic agents, EGCG and Thymoquinone, delivered by sustained drug delivery on colon cancer cells.
- Thymoquinone triggers anti-apoptotic signaling targeting death ligand and apoptotic regulators in a model of hepatic ischemia reperfusion injury
- Thymoquinone, a potential therapeutic agent of Nigella sativa, binds to site I of human serum albumin
- Redox cycling of endogenous copper by Thymoquinone leads to ROS-mediated DNA breakage and consequent cell death: putative anticancer mechanism of …
- Thymoquinone ameliorates acute renal failure in gentamicin-treated adult male rats
- Enrichment of the Thymoquinone content in volatile oil from Satureja montana using supercritical fluid extraction
- Protective role of Thymoquinone against liver damage induced by tamoxifen in female rats
- Thymoquinone improves aging-related endothelial dysfunction in the rat mesenteric artery
- Thymoquinone induces apoptosis in oral cancer cells through p38β inhibition
- Protective effect of Nigella sativa and Thymoquinone on serum/glucose deprivation-induced DNA damage in PC12 cells
- Thymoquinone inhibits proliferation and invasion of human nonsmall-cell lung cancer cells via ERK pathway
- Thymoquinone inhibits the CXCL12-induced chemotaxis of multiple myeloma cells and increases their susceptibility to Fas-mediated apoptosis
- Pharmacokinetic plasma behaviors of intravenous and oral bioavailability of Thymoquinone in a rabbit model
- Therapeutic implications of black seed and its constituent Thymoquinone in the prevention of cancer through inactivation and activation of molecular pathways
- Aqueous solubility and degradation kinetics of the phytochemical anticancer Thymoquinone; probing the effects of solvents, pH and light
- Thymoquinone induces apoptosis in malignant T-cells via generation of ROS.
- The effect of nigellone and Thymoquinone on inhibiting trachea contraction and mucociliary clearance
- Thymoquinone prevents β-amyloid neurotoxicity in primary cultured cerebellar granule neurons
- … -density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by Thymoquinone-rich fraction and Thymoquinone in HepG2 cells
- Thymoquinone attenuates lung injury induced by chronic toluene exposure in rats
- A review of the effects of Nigella sativa L. and its constituent, Thymoquinone, in metabolic syndrome
- Crystal structure determination of Thymoquinone by high-resolution X-ray powder diffraction
- Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets
- Thymoquinone blocks pSer/pThr recognition by Plk1 Polo-box domain as a phosphate mimic
- Thymoquinone therapy abrogates toxic effect of cadmium on rat testes
- Anti-cancer effects of Thymoquinone in mouse neuroblastoma (Neuro-2a) cells through caspase-3 activation with down-regulation of XIAP
- Thymoquinone-induced relaxation of isolated rat pulmonary artery
- Protective effect of Thymoquinone on glucose or methylglyoxal-induced glycation of superoxide dismutase
- Thymoquinone reduces migration and invasion of human glioblastoma cells associated with FAK, MMP-2 and MMP-9 down-regulation
- Thymoquinone blocks lung injury and fibrosis by attenuating bleomycin-induced oxidative stress and activation of nuclear factor Kappa-B in rats
- Thymoquinone decreases F-actin polymerization and the proliferation of human multiple myeloma cells by suppressing STAT3 phosphorylation and Bcl2/Bcl …
- Thymoquinone‐induced platelet apoptosis
- The effects of Nigella sativa hydro-alcoholic extract and Thymoquinone on lipopolysaccharide-induced depression like behavior in rats
- Antihyperglycemic effect of Thymoquinone and oleuropein, on streptozotocin-induced diabetes mellitus in experimental animals
- Thymoquinone and curcumin attenuate gentamicin-induced renal oxidative stress, inflammation and apoptosis in rats
- PEGylated-Thymoquinone–
nanoparticle mediated retardation of breast cancer cell migration by deregulation of cytoskeletal actin polymerization through miR-34a - Thymoquinone anticancer discovery: possible mechanisms
- Protective effects of Thymoquinone on the neuronal injury in frontal cortex after chronic toluene exposure
- Thymoquinone attenuates cypermethrin induced oxidative stress in Swiss albino mice
- Effects of Thymoquinone on STZ-induced diabetic nephropathy: an immunohistochemical study
- Thymoquinone reestablishes spermatogenesis after testicular injury caused by chronic toluene exposure in rats
- Thymoquinone inhibits TNF-α-induced inflammation and cell adhesion in rheumatoid arthritis synovial fibroblasts by ASK1 regulation
- Effect of Thymoquinone, a constituent of Nigella sativa L., on ischemia–reperfusion in rat skeletal muscle
- Protective effect of Thymoquinone against lead-induced hepatic toxicity in rats
- The use of Thymoquinone in nephrotoxicity related to acetaminophen
- Thymoquinone: a promising antidiabetic agent
- Effect of Thymoquinone on hepatorenal dysfunction and alteration of CYP3A1 and spermidine/spermine N‐1‐acetyl‐transferase gene expression induced by renal …
- Thymoquinone, the Nigella sativa Bioactive Compound, Prevents Circulatory Oxidative Stress Caused by 1,2-Dimethylhydrazine in Erythrocyte during Colon …
- Thymoquinone-loaded PLGA nanoparticles: antioxidant and anti-microbial properties
- Thymoquinone inhibits IL-1β-induced inflammation in human osteoarthritis chondrocytes by suppressing NF-κB and MAPKs signaling pathway
- Thymoquinone attenuates tumor growth in Apc Min mice by interference with Wnt-signaling
- Cellular responses with Thymoquinone treatment in human breast cancer cell line MCF-7
- Evaluation of antifungal activities of the essential oil and various extracts of Nigella sativa and its main component, Thymoquinone against pathogenic dermatophyte …
- Thymoquinone overcomes chemoresistance and enhances the anticancer effects of bortezomib through abrogation of NF-κB regulated gene products in …
- Protective effects of Thymoquinone against cholestatic oxidative stress and hepatic damage after biliary obstruction in rats
- Effect of Thymoquinone on 1, 2-dimethyl-hydrazine-induced oxidative stress during initiation and promotion of colon carcinogenesis
- Synthesis, characterization and anti-tumor activity of novel Thymoquinone analogs against pancreatic cancer
- Thymoquinone protects cultured hippocampal and human induced pluripotent stem cells-derived neurons against α-synuclein-induced synapse damage
- Thymoquinone accelerates osteoblast differentiation and activates bone morphogenetic protein-2 and ERK pathway
- Physiological responses of ES-2 ovarian cell line following administration of epigallocatechin-3-gallate (EGCG), Thymoquinone (TQ), and selenium (SE).
- Inhibitory effects of Thymoquinone from Nigella sativa on pathogenic Saprolegnia in fish
- Effects of Thymoquinone rich fraction and Thymoquinone on plasma lipoprotein levels and hepatic low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl …
- Thymoquinone attenuates toxicity and oxidative stress induced by bisphenol A in liver of male rats
- Quantification and evaluation of Thymoquinone loaded mucoadhesive nanoemulsion for treatment of cerebral ischemia
- In vitro challenge using Thymoquinone on hepatocellular carcinoma (HepG2) cell line
- Thymoquinone inhibits cell proliferation through regulation of G1/S phase cell cycle transition in N-nitrosodiethylamine-induced experimental rat hepatocellular …
- Neuroprotective effects of mitochondria-targeted plastoquinone and Thymoquinone in a rat model of brain ischemia/reperfusion injury
- Protective effects of Thymoquinone against apoptosis and oxidative stress by arsenic in rat kidney
- A new agent for treatment of acute respiratory distress syndrome: Thymoquinone. An experimental study in a rat model
- Regulation of apolipoprotein A‐1 and apolipoprotein B100 genes by Thymoquinone rich fraction and Thymoquinone in HepG2 cells
- The comparison of anticancer activity of Thymoquinone and nanoThymoquinone on human breast adenocarcinoma
- Protective effects of Thymoquinone and methotrexate on the renal injury in collagen-induced arthritis
- Neuroprotective effects of Thymoquinone against spinal cord ischemia-reperfusion injury by attenuation of inflammation, oxidative stress, and apoptosis
- Rearrangement of azidoquinones. Reaction of Thymoquinone and 2, 5-dimethyl-1, 4-benzoquinone with sodium azide in trichloroacetic acid
- Impact of protein binding on the analytical detectability and anticancer activity of Thymoquinone
- On the structure of the photodimer of Thymoquinone
- Thymoquinone prevents RANKL-induced osteoclastogenesis activation and osteolysis in an in vivo model of inflammation by suppressing NF-KB and MAPK …
- Attenuation of the development of hypercholesterolemic atherosclerosis by Thymoquinone
- Amelioration of chronic relapsing experimental autoimmune encephalomyelitis (cr-eae) using Thymoquinone-biomed 2009.
- Down-regulation of cyclic nucleotide phosphodiesterase PDE1A is the key event of p73 and UHRF1 deregulation in Thymoquinone-induced acute lymphoblastic …
- Thymoquinone enhances the activities of enzymes related to energy metabolism in peripheral leukocytes of diabetic rats
- Thymoquinone induces cell death in human squamous carcinoma cells via caspase activation-dependent apoptosis and LC3-II activation-dependent …
- Extractive components from INCENSE-cedar heartwood (Libocedrus decurrens Torrey) I. Occurrence of carvacrol, hydroThymoquinone, and Thymoquinone
- Anti-inflammatory and antioxidant activity of Thymoquinone in a rat model of acute bacterial prostatitis
- Effects of Thymoquinone and selenium on the proliferation of mg 63 cells in tissue culture.
- Elucidation of mechanisms of actions of Thymoquinone-enriched methanolic and volatile oil extracts from Nigella sativa against cardiovascular risk parameters …
- A simple differential pulse polarographic method for the determination of Thymoquinone in black seed oil
- Immunomodulatory and cytotoxic effects of Nigella sativa and Thymoquinone on rat splenocytes
- Thymoquinone ameliorates cadmium-induced nephrotoxicity, apoptosis, and oxidative stress in rats is based on its anti-apoptotic and anti-oxidant properties
- Thymoquinone-induced reactive oxygen species causes apoptosis of chondrocytes via PI3K/Akt and p38kinase pathway
- Antioxidative and anti-inflammatory effect of Thymoquinone in an acute Pseudomonas prostatitis rat model
- Thymoquinone inhibits lipopolysaccharide-induced inflammatory mediators in BV2 microglial cells
- Therapeutic effects of Thymoquinone in a model of neuropathic pain
- Dual drug-loaded paclitaxel–Thymoquinone nanoparticles for effective breast cancer therapy
- Inhibition of brain oxidative stress and inducible nitric oxide synthase expression by Thymoquinone attenuates the development of morphine tolerance and …
- Thymoquinone Restores Radiation‐Induced TGF‐β Expression and Abrogates EMT in Chemoradiotherapy of Breast Cancer Cells
- Anti-asthmatic and anti-allergic effects of Thymoquinone on airway-induced hypersensitivity in experimental animals
- Protective effect of Thymoquinone against high-fructose diet-induced metabolic syndrome in rats
- Cytotoxicity of Thymoquinone (TQ) from Nigella sativa towards human cervical carcinoma cells (HeLa)
- Enhancement of bioavailability and pharmacodynamic effects of Thymoquinone via nanostructured lipid carrier (NLC) formulation
- Thymoquinone suppressses in vitro production of IL-5 and IL-13 by mast cells in response to lipopolysaccharide stimulation
- Thymoquinone induces G2/M arrest, inactivates PI3K/Akt and nuclear factor-κB pathways in human cholangiocarcinomas both in vitro and in vivo
- Beneficial interaction of Thymoquinone and sodium valproate in experimental models of epilepsy: reduction in hepatotoxicity of valproate
- Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo
- Study on the potential toxicity of a Thymoquinone-rich fraction nanoemulsion in Sprague Dawley rats
- Upregulation of Chemoprotective Enzymes and Glutathione by Nigella sativa (Black Seed) and Thymoquinone in CCl4-Intoxicated Rats
- Thymoquinone, a bioactive component of black caraway seeds, causes G1 phase cell cycle arrest and apoptosis in triple-negative breast cancer cells with mutant p53
- Thymoquinone attenuates astrogliosis, neurodegeneration, mossy fiber sprouting, and oxidative stress in a model of temporal lobe epilepsy
- NADPH quinone oxidoreductase 1 mediates breast cancer cell resistance to Thymoquinone-induced apoptosis
- Attenuation of high cholesterol-induced oxidative stress in rabbit liver by Thymoquinone
- Radiation-modifying abilities of Nigella sativa and Thymoquinone on radiation-induced nitrosative stress in the brain tissue
- Thymoquinone induces apoptosis in human colon cancer HCT116 cells through inactivation of STAT3 by blocking JAK2-and Src‑mediated phosphorylation of …
- Apoptotic activities of Thymoquinone, an active ingredient of black seed (Nigella sativa), in cervical cancer cell lines
- Thymoquinone inhibits inflammation, neoangiogenesis and vascular remodeling in asthma mice
- Effects of combinations of curcumin, linalool, rutin, safranal, and Thymoquinone on glucose/serum deprivation-induced cell death
- Thymoquinone supplementation ameliorates lead-induced testis function impairment in adult rats
- Thymoquinone suppression of the human hepatocellular carcinoma cell growth involves inhibition of IL-8 expression, elevated levels of TRAIL receptors, oxidative …
- Thymoquinone-loaded nanostructured lipid carrier exhibited cytotoxicity towards breast cancer cell lines (MDA-MB-231 and MCF-7) and cervical cancer cell lines …
- Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer
- The effect of Thymoquinone, an active component of Nigella sativa, on isoproterenol induced myocardial injury
- Mitigation of Obesity-Promoted Diseases by Nigella sativa and Thymoquinone
- Thymoquinone alleviates nonalcoholic fatty liver disease in rats via suppression of oxidative stress, inflammation, apoptosis
- Protective effects of Thymoquinone and melatonin on intestinal ischemia–reperfusion injury
- Intestinal, airway, and cardiovascular relaxant activities of Thymoquinone
- Evaluation of the protective effect of Nigella sativa extract and its primary active component Thymoquinone against DMBA-induced breast cancer in female rats
- Thymoquinone hydrazone derivatives cause cell cycle arrest in p53-competent colorectal cancer cells
- Pronounced transcriptional regulation of apoptotic and TNF–NF-kappa-B signaling genes during the course of Thymoquinone mediated apoptosis in HeLa cells
- Overcoming Akt induced therapeutic resistance in breast cancer through siRNA and Thymoquinone encapsulated multilamellar gold niosomes
- Antioxidant Property, Thymoquinone Content and Chemical Characteristics of Different Extracts from Nigella sativa L. Seeds
- Thymoquinone chemosensitizes colon cancer cells through inhibition of NF‑κB
- Novel combination of docetaxel and Thymoquinone induces synergistic cytotoxicity and apoptosis in DU-145 human prostate cancer cells by modulating PI3K–AKT …
- Thymoquinone ameliorates bacterial translocation and inflammatory response in rats with intestinal obstruction
- Ameliorative effect of Thymoquinone on ovalbumin-induced allergic conjunctivitis in Balb/c mice
- Thymoquinone inhibits Escherichia coli ATP synthase and cell growth
- Thymoquinone alleviates the experimental diabetic peripheral neuropathy by modulation of inflammation
- Modulation of hepatic drug metabolizing enzymes by dietary doses of Thymoquinone in female New Zealand White rabbits
- Thymoquinone inhibits murine leukemia WEHI-3 cells in vivo and in vitro
- The effect of single dose of Thymoquinone, the main constituents of Nigella sativa, in guinea pig model of asthma
- Thymoquinone improves the kidney and liver changes induced by chronic cyclosporine A treatment and acute renal ischaemia/reperfusion in rats
- A review on the hypoglycemic effect of Nigella sativa and Thymoquinone
- Thymoquinone inhibits phorbol ester-induced activation of NF-κB and expression of COX-2, and induces expression of cytoprotective enzymes in mouse skin in vivo
- Anti-neoplastic agent Thymoquinone induces degradation of α and β tubulin proteins in human cancer cells without affecting their level in normal human fibroblasts
- Antidepressant effect of Thymoquinone in animal models of depression
- Thymoquinone a potential therapy for cerebral oxidative stress
- The effect of conventional and sustained delivery of Thymoquinone and levodopa on SH-SY5Y human neuroblastoma cells.
- Thymoquinone induces apoptosis and increase ROS in ovarian cancer cell line
- Thymoquinone, the active ingredient of Nigella sativa seeds, enhances survival and activity of antigen-specific CD8-positive T cells in vitro
- Identification of potential sources of Thymoquinone and related compounds in Asteraceae, Cupressaceae, Lamiaceae, and Ranunculaceae families
- Thymoquinone and Vitamin C Attenuates Pentylenetetrazole-Induced Seizures Via Activation of GABAB1 Receptor in Adult Rats Cortex and Hippocampus
- The histopathological effect of Thymoquinone on experimentally induced rhinosinusitis in rats
- Protective effects of Thymoquinone against methotrexate-induced germ cell apoptosis in male mice
- Stability‐indicating ultra‐performance liquid chromatography method for the estimation of Thymoquinone and its application in biopharmaceutical studies
- Thymoquinone pretreatment overcomes the insensitivity and potentiates the antitumor effect of gemcitabine through abrogation of Notch1, PI3K/Akt/mTOR regulated …
- Characterization of Thymoquinone binding to human α1-acid glycoprotein
- The Thymoquinone-induced production of reactive oxygen species promotes dedifferentiation through the ERK pathway and inflammation through the p38 and …
- Preparation, characterization and antiproliferative activity of Thymoquinone-β-cyclodextrin self assembling nanoparticles
- Effect of Thymoquinone on oxidative stress in Escherichia coli–induced pyelonephritis in rats
- Natural products as topoisomerase II poisons: Effects of Thymoquinone on DNA cleavage mediated by human topoisomerase IIα
- A structural study on the protection of glycation of superoxide dismutase by Thymoquinone
- Thymoquinone induces caspase-independent, autophagic cell death in CPT-11-resistant lovo colon cancer via mitochondrial dysfunction and activation of JNK and …
- Thymoquinone supplementation reverses lead-induced oxidative stress in adult rat testes.
- The physiological effect of conventional treatment with epigallocatechin-3-gallate, Thymoquinone, and tannic acid on the LNCaP cell line.
- Role of NF-κB in the anti-tumor effect of Thymoquinone on bladder cancer
- Thymoquinone inhibits microtubule polymerization by tubulin binding and causes mitotic arrest following apoptosis in A549 cells
- Thymoquinone effectively alleviates lung fibrosis induced by paraquat herbicide through down-regulation of pro-fibrotic genes and inhibition of oxidative stress
- Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro
- Nigella sativa and its active constituent Thymoquinone in oral health
- Thymoquinone synergistically potentiates temozolomide cytotoxicity through the inhibition of autophagy in U87MG cell line
- Effects of intraperitoneal Thymoquinone on chronic neuropathic pain in rats
- Nigella sativa seed extract and its bioactive compound Thymoquinone: the new melanogens causing hyperpigmentation in the wall lizard melanophores
- Combinatorial effects of Thymoquinone on the anticancer activity and hepatotoxicity of the prodrug CB 1954
- Effect of Thymoquinone on P53 gene expression and consequence apoptosis in breast cancer cell line
- Mesalazine and Thymoquinone attenuate intestinal tumour development in Msh2loxP/loxP Villin-Cre mice
- Maternal supplementation of diabetic mice with Thymoquinone protects their offspring from abnormal obesity and diabetes by modulating their lipid profile and …
- Analysis on chemical components of volatile oil and determination of Thymoquinone from seed of Nigella glandulifera
- Protective effect of Thymoquinone against cyclophosphamide-induced hemorrhagic cystitis through inhibiting DNA damage and upregulation of Nrf2 …
- Validated high‐performance thin‐layer chromatographic method for the quantification of Thymoquinone in Nigella Sativa extracts and formulations
- Thymoquinone protects against myocardial ischemic injury by mitigating oxidative stress and inflammation
- Chemopreventive and therapeutic potentials of Thymoquinone in HepG2 cells: mechanistic perspectives
- Alleviation of plasma, erythrocyte and liver lipidemic-oxidative stress by Thymoquinone and limonene in atherogenic suspension fed rats
- Thymoquinone from nutraceutical black cumin oil activates Neu4 sialidase in live macrophage, dendritic, and normal and type I sialidosis human fibroblast cells via …
- Cardioprotective effect of Thymoquinone: A constituent of Nigella sativa L., against myocardial ischemia/reperfusion injury and ventricular arrhythmias in …
- Characterization and stability evaluation of Thymoquinone nanoemulsions prepared by high-pressure homogenization
- Mitigating role of Thymoquinone rich fractions from Nigella sativa oil and its constituents, Thymoquinone and limonene on lipidemic-oxidative injury in rats
- Biophysical investigation of Thymoquinone binding to ‘N’and ‘B’isoforms of human serum albumin: exploring the interaction mechanism and radical scavenging activity
- Effect of Thymoquinone on ethanol and high fat diet induced chronic pancreatitis—a dose response study in rats
- Synergistic effects of Thymoquinone and curcumin on immune response and anti-viral activity against avian influenza virus (H9N2) in turkeys
- Effect of Thymoquinone on cytosolic pH and Na+/H+ exchanger activity in mouse dendritic cells
- Potential implications of GRP58 expression and susceptibility of cervical cancer to cisplatin and Thymoquinone-based therapy
- Protective effect of Thymoquinone against testicular torsion induced oxidative injury
- Thymoquinone enhances cisplatin-response through direct tumor effects in a syngeneic mouse model of ovarian cancer
- Reduction of hypervalent states of myoglobin and hemoglobin to their ferrous forms by Thymoquinone: the role of GSH, NADH and NADPH
- Liposomal Thymoquinone effectively combats fluconazole-resistant Candida albicans in a murine model
- Ameliorative effects of Thymoquinone against eye lens changes in streptozotocin diabetic rats
- Attenuation of oxidative stress-induced vascular endothelial dysfunction by Thymoquinone
- Protective effects of Thymoquinone and l-cysteine on cadmium-induced reproductive toxicity in rats
- Interaction of human telomeric G-quadruplex DNA with Thymoquinone: a possible mechanism for Thymoquinone anticancer effect
- The protective role of Thymoquinone in the prevention of gentamicin ototoxicity
- Thymoquinone β-Cyclodextrin Nanoparticles System: A Preliminary Study
- Thymoquinone from Nigella sativa seeds promotes the antitumor activity of noncytotoxic doses of topotecan in human colorectal cancer cells in vitro
- Thymoquinone ameliorates lead-induced suppression of the antioxidant system in rat kidneys
- Evaluation of chemopreventive effects of Thymoquinone on cell surface glycoconjugates and cytokeratin expression during DMBA induced hamster buccal pouch …
- The combination of Thymoquinone and paclitaxel shows anti-tumor activity through the interplay with apoptosis network in triple-negative breast cancer
- Microenvironmental effects limit efficacy of Thymoquinone treatment in a mouse model of ovarian cancer
- Thymoquinone strongly inhibits fMLF-induced neutrophil functions and exhibits anti-inflammatory properties in vivo
- Upregulation of SIRT1-AMPK by Thymoquinone in hepatic stellate cells ameliorates liver injury
- Protective effect of Thymoquinone on cholestatic rats with liver injury
- Antiproliferative and proapoptotic effects of topotecan in combination with Thymoquinone on acute myelogenous leukemia
- Effects of Thymoquinone, lycopene, and selenomethione in the presence of estrogen on the viability of SiHa cells in vitro.
- Acute and subacute toxicity profiles of Thymoquinone-loaded nanostructured lipid carrier in BALB/c mice
- Thymoquinone, an active constituent of Nigella sativa seeds, binds with bilirubin and protects mice from hyperbilirubinemia and cyclophosphamide-induced …
- Thymoquinone protects end organs from abdominal aorta ischemia/reperfusion injury in a rat model
- Protective mechanisms of Thymoquinone on methotrexate-induced intestinal toxicity in rats
- Synthesis, morphology and antifungal activity of nano-particulated amphotericin-B, ketoconazole and Thymoquinone against Candida albicans yeasts and Candida …
- A review of Neuropharmacology Effects of Nigella sativa and Its Main Component, Thymoquinone
- Anticancer drugs with chemotherapeutic interactions with Thymoquinone in osteosarcoma cells
- The effect of Thymoquinone on the renal functions following ischemia-reperfusion injury in the rat
- Attenuation of morphine tolerance and dependence by Thymoquinone in mice
- Anti-diabetic properties of Thymoquinone is unassociated with glycogen phosphorylase inhibition
- Modulation of hydrogen peroxide-induced oxidative stress in human neuronal cells by Thymoquinone-rich fraction and Thymoquinone via transcriptomic regulation of …
- Implication of Thymoquinone as a remedy for polycystic ovary in rat
- Study on the anticonvulsant activity of Thymoquinone, the major constituent of Nigella sativa L. seeds, through intracerebroventricular injection
- The effect of Thymoquinone treatment on the combined renal and pulmonary toxicity of cisplatin and diesel exhaust particles
- Thymoquinone vapor significantly affects the results of Staphylococcus aureus sensitivity tests using the standard broth microdilution method
- ANTIFUNGAL EFFECT OF THYMOL, Thymoquinone AND THYMOHYDROQUINONE AGAINST YEASTS, DERMATOPHYTES AND NON-DERMATOPHYTE …
- Protective effect of Thymoquinone improves cardiovascular function, and attenuates oxidative stress, inflammation and apoptosis by mediating the PI3K/Akt …
- Insights into the molecular interactions of Thymoquinone with histone deacetylase: evaluation of the therapeutic intervention potential against breast cancer
- Thymoquinone, a bioactive component of Nigella sativa, normalizes insulin secretion from pancreatic β-cells under glucose overload via regulation of malonyl-CoA
- The Th1/Th2 paradigm in lambda cyhalothrin-induced spleen toxicity: the role of Thymoquinone
- The antioxidant effects of Thymoquinone in activated BV-2 murine microglial cells
- Phosphorylated IκBα predicts poor prognosis in activated B-cell lymphoma and its inhibition with Thymoquinone induces apoptosis via ROS release
- Thymoquinone: An edible redox-active quinone for the pharmacotherapy of neurodegenerative conditions and glial brain tumors. A short review
- Thymoquinone subdues tumor growth and potentiates the chemopreventive effect of 5-fluorouracil on the early stages of colorectal carcinogenesis in rats
- Neuroprotective effects of Thymoquinone on the hippocampus in a rat model of traumatic brain injury