HSP90
January 6, 2020PREMATURE SENESCENCE
January 7, 2020- A branching process model of telomere shortening
- A continuous correlation between oxidative stress and telomere shortening in fibroblasts
- A Critical Role for Pin2/TRF1 in ATM-dependent Regulation
- INHIBITION OF Pin2/TRF1 FUNCTION COMPLEMENTS telomere shortening, RADIOSENSITIVITY, AND THE G2/M CHECKPOINT DEFECT OF ATAXIA-TELANGIECTASIA CELLS
- A G-quadruplex-interactive agent, telomestatin (SOT-095), induces telomere shortening with apoptosis and enhances chemosensitivity in acute myeloid leukemia
- A Home Use Study in Healthy Volunteers to Assess Effectiveness of a Dietary Supplement to Halt the Shortening of telomere Length as Demonstrated by the “ …
- A kinetic model of telomere shortening in infants and adults
- A protein array screen for Kaposi’s sarcoma-associated herpesvirus LANA interactors links LANA to TIP60, PP2A activity, and telomere shortening
- A randomized-controlled clinical study of Telos95®, a novel antioxidative dietary supplement, on the shortening of telomere length in healthy volunteers
- A stochastic model of cell replicative senescence based on telomere shortening, oxidative stress, and somatic mutations in nuclear and mitochondrial DNA
- A tel2 Mutation That Destabilizes the Tel2-Tti1-Tti2 Complex Eliminates Rad3ATR Kinase Signaling in the DNA Replication Checkpoint and Leads to telomere shortening in Fission Yeast
- A TIN2 dyskeratosis congenita mutation causes telomerase-independent telomere shortening in mice
- A15812 Angiotensin Converting Enzyme Inhibitors Epigenetically Atenuate telomere shortening
- A7. 9 Does telomere shortening in Women with Rheumatoid Arthritis Predict X Chromosome Inactivation Bias?
- AB181. telomere shortening is associated with genetic anticipation in Chinese Von Hippel-Lindau disease families
- Abnormal telomere shortening in leucocytes of children with Shwachman–Diamond syndrome
- Abnormal telomere shortening of peripheral blood mononuclear cells and granulocytes in patients with chronic idiopathic neutropenia
- Abrogation of miR-195 Improves Function in Aged Heart by Preventing telomere shortening and Mitochondrial Dysfunction
- Abrupt telomere shortening in cell aging and cancer
- Abrupt telomere shortening in normal human fibroblasts
- Absence of telomere shortening and oxidative DNA damage in the young adult offspring of women with pre-gestational type 1 diabetes
- Abstract A63: Rsf-1, a chromatin remodeling protein, interacts with shelterin protein hRap1 and induces telomere shortening
- Abstract# 3036: telomere length shortening in individuals with sporadic compared with familial breast cancer
- Abstract# 3482: telomere shortening in human tumor cells in vitro and in vivo following treatment with telomerase inhibitor, GRN163L
- Abstract# 4505: Peripheral telomere shortening is most closely associated with young age of onset for pancreatic cancer
- Abstract# 5139: The inflammatory cytokine TNF-\# 945; induces rapid, reversible telomere shortening in breast cancer cell lines
- Accelerated aging as evidenced by increased telomere shortening and mitochondrial DNA depletion in patients with type 2 diabetes
- Accelerated telomere length shortening in granulocytes: a diagnostic marker for myeloproliferative diseases
- Accelerated telomere shortening and replicative senescence in human fibroblasts overexpressing mutant and wild-type lamin A
- Accelerated telomere shortening and senescence in human pancreatic islet cells stimulated to divide in vitro
- Accelerated telomere shortening and telomerase activation in Fanconi’s anaemia
- Accelerated telomere shortening and telomere abnormalities in radiosensitive cell lines
- Accelerated telomere shortening following allogeneic transplantation is independent of the cell source and occurs within the first year post transplant
- Accelerated telomere shortening in acromegaly; IGF-I induces telomere shortening and cellular senescence
- Accelerated telomere shortening in ataxia telangiectasia
- Accelerated telomere shortening in bonemarrow recipients
- Accelerated telomere shortening in CD8+ T-lymphocytes From Patients With Coronary Heart Disease Links Cytomegalovirus-Induced T Cell Response and …
- Accelerated telomere shortening in Fanconi anemia fibroblasts–a longitudinal study
- Accelerated telomere shortening in fibroblasts after extended periods of confluency
- Accelerated telomere shortening in peripheral blood lymphocytes after occupational polychlorinated biphenyls exposure
- Accelerated telomere shortening in Response to Air Pollution from Traffic Emissions.
- Accelerated telomere shortening in response to life stress
- Accelerated telomere shortening in rheumatic diseases: cause or consequence?
- Accelerated telomere shortening in the human inactive X chromosome
- Accelerated telomere shortening in young recipients of allogeneic bone-marrow transplants
- Accelerated telomere shortening in β-thalassemia/HbE patients
- Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation …
- Accelerated telomere shortening: Tracking the lasting impact of early institutional care at the cellular level
- Accumulation of single-strand breaks is the major cause of telomere shortening in human fibroblasts
- Advanced telomere shortening in respiratory chain disorders
- Age estimation in dental pulp DNA based on human telomere shortening
- Age-associated telomere shortening in mouse oocytes
- Age-associated telomere shortening in Thoroughbred horses
- Age-dependent telomere shortening is slowed down by enrichment of intracellular vitamin C via suppression of oxidative stress
- Age‐dependent telomere‐shortening is repressed by phosphorylated α‐tocopherol together with cellular longevity and intracellular oxidative‐stress reduction in …
- Age-independent telomere shortening and ion-channel defects in SCD
- Ageing and telomeres: a study into organ‐and gender‐specific telomere shortening
- Age-related telomere shortening occurs in lens epithelium from old rats and is slowed by caloric restriction
- Age-related telomere uncapping is associated with cellular senescence and inflammation independent of telomere shortening in human arteries
- Age-Related telomere Uncapping Occurs Independent of telomere shortening in Mouse Endothelial Cells
- Aging-related telomere shortening and cognitive decline in the Betula study: No evidence of coupled changes
- Alpha-tocopherol modulates hydrogen peroxide-induced DNA damage and telomere shortening of human skin fibroblasts derived from differently aged individuals
- Amplification of the human epidermal growth factor receptor 2 gene in differentiated thyroid cancer correlates with telomere shortening
- An association between telomere shortening and disease evolution patterns in MDS
- An investigation on mitochondrial DNA deletions and telomere shortening during multiple passages of adult stem cells
- An Isogenic Trisomic–Disomic Model System Using Cells from People with Mosaic Down Syndrome Unmasks Trisomy 21 Associated Increases in Age-Related Chromosomal Instability, Senescence Associated Distension of Satellites, and telomere shortening
- Analysis of the telomere shortening in the cloned caprine cultured cell line, CPF-1, derived from placenta of Shiba goat (Capra hircus)
- Ancestral telomere shortening: A countdown that will increase mean life span?
- Angiotensin II type 1 receptor gene polymorphism and telomere shortening in essential hypertension
- Antisense oligonucleotide-mediated inhibition of hTERT, but not hTERC, induces rapid cell growth decline and apoptosis in the absence of telomere shortening in human prostate cancer cells
- Artemisinin mimics calorie restriction to initiate antioxidative responses and compromise telomere shortening
- Artemisinin mimics calorie restriction to trigger mitochondrial biogenesis and compromise telomere shortening in mice
- Artificial light at night does not affect telomere shortening in a developing free-living songbird: A field experiment: Artificial light at night and telomere dynamics
- Asp-Ala-His-Lys (DAHK) inhibits copper-induced oxidative DNA double strand breaks and telomere shortening
- Association between antidiabetic agents use and leukocyte telomere shortening rates in patients with type 2 diabetes
- Association between leukocyte telomere shortening and exposure to traffic pollution: a cross-sectional study on traffic officers and indoor office workers
- Association between oxidative DNA damage and telomere shortening in circulating endothelial progenitor cells obtained from metabolic syndrome patients with …
- Association between telomere shortening and ageing during occupational exposure
- Association of Immune Abnormalities with telomere shortening in
- Association of telomere shortening in myocardium with heart weight gain and cause of death
- Association of telomere shortening with impaired glucose tolerance and diabetic macroangiopathy
- Asynchronous Shortening of telomere Length and Cardiovascular Outcomes
- ATF7 mediates TNF-α–induced telomere shortening
- Authors’ Response Correlation between baseline telomere length and shortening over time—spurious or true?
- Biological age instead of chronologic age as prognostic factor in IPF: clinical implications of telomere shortening
- Biomarkers of oxidative stress: methods and measures of oxidative DNA damage (COMET assay) and telomere shortening
- BJ fibroblasts display high antioxidant capacity and slow telomere shortening independent of hTERT transfection
- Blood cell telomere lengths and shortening rates of chimpanzee and human females
- Bone morphogenetic protein-7 induces telomerase inhibition, telomere shortening, breast cancer cell senescence, and death via Smad3.
- C21 MECHANISMS THAT LINK AGING WITH LUNG DISEASE: THE CUTTING EDGE: Acrolein Induces P53-Mediated Cellular Senescence Accompanied By Enhanced Werner’s Syndrome Protein Degradation And telomere shortening
- Can leukocyte telomere shortening be a possible biomarker to track Huntington’s disease progression?
- Can telomere shortening be the main indicator of non-viable fetus elimination?
- Can telomere shortening explain sigmoidal growth curves?
- Can telomere shortening in human peripheral blood leukocytes serve as a disease biomarker of Friedreich’s ataxia?
- Candidate drug BIBR1532 induces telomere shortening and growth inhibition in lymphoid cell lines
- Cardiomyocyte-Specific telomere shortening is a Distinct Signature of Heart Failure in Human
- Cardiomyocyte‐Specific telomere shortening is a Distinct Signature of Heart Failure in Humans
- Casein Kinase II (csnk2a2) is Associated With Leucocyte telomere shortening and Increased Cardiovascular Disease Risk in Diabetes
- CD 57 identifies T cells with functional senescence before terminal differentiation and relative telomere shortening in patients with activated PI 3 kinase delta …
- Celiac disease autoimmunity is associated with leukocyte telomere shortening in older adults: the US National Health and Nutrition Examination Survey
- Cell contact accelerates replicative senescence of human mesenchymal stem cells independent of telomere shortening and p53 activation: roles of Ras and oxidative …
- CELL CYCLE ARREST AND ACCELERATED telomere shortening IN NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD)
- Cell cycle-dependent and-independent telomere shortening accompanies murine brain aging
- Cell senescence and telomere shortening induced by a new series of specific G-quadruplex DNA ligands
- Cell senescence in rat kidneys in vivo increases with growth and age despite lack of telomere shortening
- Cellular consequences of telomere shortening in histologically normal breast tissues
- Cellular senescence mechanisms independent of telomere shortening and telomerase: other barriers to cell immortalization and carcinogenesis
- CEREBRAL VASCULAR HEALTH AND ACCELERATED LEUKOCYTE telomere shortening IN TYPE II DIABETES.
- Childhood maltreatment and telomere shortening: preliminary support for an effect of early stress on cellular aging
- Chlorella vulgaris modulates hydrogen peroxide-induced DNA damage and telomere shortening of human fibroblasts derived from different aged individuals
- Chromosomal instability and telomere shortening in long-term culture of hematopoietic stem cells: insights from a cell culture model of RPS14 haploinsufficiency
- Chromosomal instability in Barrett’s esophagus is related to telomere shortening
- Chromosomal instability in ulcerative colitis is related to telomere shortening
- Chromosomal instability, telomere shortening, and inactivation of p21WAF1/CIP1 in dysplastic nodules of hepatitis B virus-associated multistep …
- Chromosomal telomere shortening of kidney cells in IgA nephropathy by the measurement of DNA in urinary sediment.
- Chronic Oxidative Stress Leads To Accelerated telomere shortening In Children With Alpha-1 Antitrypsin Deficiency
- Chronic psychosocial and financial burden accelerates 5-year telomere shortening: findings from the Coronary Artery Risk Development in Young Adults Study
- Clinical impact of telomere shortening in normal and leukemia cells in chronic lymphocytic leukemia
- Clinical predictive factors and prognostic implications of telomere shortening in sporadic and familial idiopathic pulmonary fibrosis
- Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible …
- Cocaine use may induce telomere shortening in individuals with HIV infection
- Colonocyte telomere shortening is greater with dietary red meat than white meat and is attenuated by resistant starch
- Comments on “Is telomere shortening reversible? A clue from NASA’s twins mission”
- Comparison of Southern blotting and Real-time PCR in measuring telomere shortening
- Concomitant telomere shortening, acquisition of multiple chromosomal aberrations and in vitro resistance to apoptosis in a single case of progressive CLL
- Consequences of acute oxidative stress in Leishmania amazonensis: From telomere shortening to the selection of the fittest parasites
- Consequences of telomere shortening at an active VSG expression site in telomerase-deficient Trypanosoma brucei
- Consequences of telomere shortening during lifespan
- Constitutive OGG1 variant together with BRCA mutations display accelerated telomere shortening
- Contact-independent suppressive activity of regulatory T cells is associated with telomerase inhibition, telomere shortening and target lymphocyte apoptosis
- Contrasting effects of telomere shortening on organ homeostasis, tumor suppression, and survival during chronic liver damage
- Convergence of adipocyte hypertrophy, telomere shortening and hypoadiponectinemia in obese subjects and in patients with type 2 diabetes
- Conversion of normal to malignant phenotype: telomere shortening, telomerase activation, and genomic instability during immortalization of human oral keratinocytes
- Correlates of telomere length shortening in peripheral leukocytes of HIV-infected individuals and association with leukoaraiosis
- Correlation of telomere length shortening with promoter methylation profile of p16/Rb and p53/p21 pathways in breast cancer
- Correlation of telomere length shortening with TP53 somatic mutations, polymorphisms and allelic loss in breast tumors and esophageal cancer
- Correlation telomere shortening in chronic lymphocytic leukemia cells with oxidative stress and dysregulation of shelterin proteins
- Correlative polymorphism of NAD (P) H: quinone oxidoreductase (NQO1) with telomere shortening in colorectal cancer.
- Cortisol increases DNA damage in lymphocytes in vitro, but is not associated with telomere shortening
- Cortisol is not associated with telomere shortening or chromosomal instability in human lymphocytes cultured under low and high folate conditions
- Critical telomere shortening regulated by the ataxia-telangiectasia gene acts as a DNA damage signal leading to activation of p53 protein and limited life-span …
- CTC1 increases the radioresistance of human melanoma cells by inhibiting telomere shortening and apoptosis
- Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells
- Data Mining in the Research and Application of telomere shortening
- Decreased dyskerin levels as a mechanism of telomere shortening in X-linked dyskeratosis congenita
- Decreasing initial telomere length in humans intergenerationally understates age‐associated telomere shortening
- Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells
- Demonstration of potential link between helicobacter pylori related promoter CpG island methylation and telomere shortening in human gastric mucosa
- Deoxyribonucleic acid telomere length shortening can predict the incidence of non‐alcoholic fatty liver disease in patients with type 2 diabetes mellitus
- Deregulated telomere transcription causes replication-dependent telomere shortening and promotes cellular senescence
- Developing a Model for Stress-Associated telomere shortening: Effects of Stress-Related Mediators on Telomerase Activity
- Development of a new multiplex quantitative real‐time PCR assay for the detection of the mtDNA4977 deletion in coronary artery disease patients: A link with telomere shortening
- Diet Influences telomere shortening: Eating Your Way to the Fountain of Youth?
- Diet-Induced Leukocyte telomere shortening Correlates with Extent of Atherosclerosis
- Diet-induced leukocyte telomere shortening in a baboon model for early stage atherosclerosis
- Diet-related telomere shortening and chromosome stability
- Different effects of accelerated development and enhanced growth on oxidative stress and telomere shortening in amphibian larvae
- Different Phase of telomere shortening with Age in Peripheral Blood Mononuclear Cells
- Different rates of telomere shortening and telomerase activity reduction in CD8 T and CD16 NK lymphocytes with ageing
- Differential expression of non-shelterin genes associated with high telomerase levels and telomere shortening in plasma cell disorders
- Differential shortening rate of telomere length in the development of human fetus
- Differential telomere shortening in blood versus arteries in an animal model of type 2 diabetes
- Differential timing of oxidative DNA damage and telomere shortening in hepatitis C and B virus–related liver carcinogenesis
- Disease anticipation is associated with progressive telomere shortening in families with dyskeratosis congenita due to mutations in TERC
- Divergent patterns of telomere shortening in tropical compared to temperate stonechats
- DNA damage and telomere length shortening in the peripheral blood leukocytes of 20 years SM-exposed veterans
- DNA Damage and telomere shortening in Embryonic Stem Cells Induced by Cigarette Smoke.
- DNA damage response correlates with telomere shortening and telomeric proteins down regulation in the colorectal multistep process
- DNA demethylation leads to telomere shortening with accelerated aging process in human diploid fibroblasts
- DNA methylation of human telomerase reverse transcriptase associated with leukocyte telomere length shortening in hyperhomocysteinemia-type hypertension in …
- Does telomere shortening precede the onset of hypertension in spontaneously hypertensive mice?
- Downregulation of methyltransferase Dnmt2 results in condition‐dependent telomere shortening and senescence or apoptosis in mouse fibroblasts
- Down-regulation of telomerase activity and replication-independent telomere shortening induced by SH-7 in human leukemia HL-60 cells
- Dynamics of telomere shortening in neutrophils and T lymphocytes during ageing and the relationship to skewed X chromosome inactivation patterns
- Dyslipidemia and chronic inflammation markers are correlated with telomere length shortening in Cushing’s syndrome
- Dysregulation of shelterin factors coupled with telomere shortening in Philadelphia chromosome negative myeloproliferative neoplasms
- Early and late steps in telomere overhang processing in normal human cells: the position of the final RNA primer drives telomere shortening
- Early growth determines longevity in male rats and may be related to telomere shortening in the kidney
- Early Senescence and Leukocyte telomere shortening in SCHIZOPHRENIA: A Role for Cytomegalovirus Infection?
- Early telomere shortening and Genomic Instability in Tubo-Ovarian Preneoplastic Lesions
- Early telomere shortening and genomic instability in tubo-ovarian preneoplastic lesions—response
- Early-senescing human skin fibroblasts do not demonstrate accelerated telomere shortening
- Effect of D-gal on mouse fibroblast telomere shortening
- Effect of maternal protein restriction upon growth, longevity and telomere shortening
- Enhanced microglial pro‐inflammatory response to lipopolysaccharide correlates with brain infiltration and blood–brain barrier dysregulation in a mouse model of telomere shortening
- Enhanced telomere shortening in transformed lymphoblasts from patients with X linked dyskeratosis
- Epigallocatechin‐3‐gallate induces telomere shortening and clastogenic damage in glioblastoma cells
- Estimating age of humans based on telomere shortening
- Estimation of human age according to telomere shortening in peripheral blood leukocytes
- Estimation of human age according to telomere shortening in peripheral blood leukocytes of Tibetan
- Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice
- Estrogen deficiency reversibly induces telomere shortening in mouse granulosa cells and ovarian aging in vivo
- EVALUATION OF DYNAMIC telomere LENGTH SHORTENING OF LYMPHOCYTES IN IMMUNOCOMPROMISED CHILDREN WITH CHRONIC DISEASES OF THE …
- Evaluation of the mechanism of nucleoplasmic bridge formation due to premature telomere shortening in agricultural workers exposed to mixed pesticides …
- Examining a scaled dynamical system of telomere shortening
- Excess Neurohormonal Activation-Induced Heart Failure Results in Significant but Non-Critical Cardiomyocyte telomere shortening, Which is Associated With …
- Excess of Yra1 RNA-Binding Factor Causes Transcription-Dependent Genome Instability, Replication Impairment and telomere shortening
- Exercise training increase antioxidant enzyme capacity and protect the shortening of telomere length
- Exome Sequencing Links Loss-of-Function and Missense Mutations in PARN and RTEL1 with Familial Pulmonary Fibrosis and telomere shortening
- Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening
- Expression of miR-23a induces telomere shortening and is associated with poor clinical outcomes in patients with coronary artery disease
- Expression of mutant RPA in human cancer cells causes telomere shortening
- Expression of TRF1, TRF2, TIN2, TERT, KU70, and BRCA1 proteins is associated with telomere shortening and may contribute to multistage carcinogenesis of gastric …
- Extracellular superoxide dismutase is a major antioxidant in human fibroblasts and slows telomere shortening
- F19. telomere shortening IN YOUNG PEOPLE WITH FIRST EPISODE PSYCHOSIS: A 12-MONTH FOLLOW-UP STUDY
- Fetal growth restriction is associated with accelerated telomere shortening and increased expression of cell senescence markers in the placenta
- Flow cytometric detection of accelerated telomere shortening in myelodysplastic syndromes: correlations with aetiological and clinical–biological findings
- Forensic application of telomere shortening in age-at-death estimation
- Fragmentation and rapid shortening of telomere in HeLa cells in the early phase of hydroxyl radical-induced apoptosis
- From cellular senescence to Alzheimer’s disease: The role of telomere shortening
- From incomplete penetrance with normal telomere length to severe disease and telomere shortening in a family with monoallelic and biallelic PARN pathogenic …
- Functional haplotypes of the hTERT gene, leukocyte telomere length shortening, and the risk of peripheral arterial disease
- Fusing Aging Theories: telomere shortening Leads to Mitochondrial Dysfunction Fusing Aging Theories: telomere shortening Leads to Mitochondrial …
- Gemcitabine causes telomere shortening by stabilizing TRF2
- Gender specific profiles of human telomere shortening during aging
- Gene disruption of a G4-DNA-dependent nuclease in yeast leads to cellular senescence and telomere shortening
- Genetic anticipation is associated with telomere shortening in hereditary breast cancer
- Genetic heterogeneity of HER2 amplification and telomere shortening in papillary thyroid carcinoma
- Genomic imbalances in key ion channel genes and telomere shortening in sudden cardiac death victims
- Genotoxic risk of ethyl‐paraben could be related to telomere shortening
- Ginger (Zingiber officinale) Extract Promotes telomere shortening and Induces Cellular Senescence in A549 Lung Cancer Cells
- Ginger Extract Promotes telomere shortening and Cellular Senescence in A549 Lung Cancer Cells
- GP 12.03 telomere shortening and telomere-associated proteins in Duchenne muscular dystrophy
- Gradual telomere shortening and increasing chromosomal instability among PanIN grades and normal ductal epithelia with and without cancer in the …
- Growth arrest, apoptosis, and telomere shortening of Barrett’s-associated adenocarcinoma cells by a telomerase inhibitor
- Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative stress‐induced premature senescence
- Growth kinetics rather than stress accelerate telomere shortening in cultures of human diploid fibroblasts in oxidative…
- Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic …
- Helicobacter pylori-induced chronic inflammation causes telomere shortening of gastric mucosa by promoting PARP-1-mediated non-homologous end joining of DNA
- Hepatocellular telomere shortening correlates with chromosomal instability and the development of human hepatoma
- Hepatocyte telomere shortening and senescence are general markers of human liver cirrhosis
- Hepatocyte telomere shortening of primary HCC correlates with increasing aneuploidy of chromosome 8
- High lead exposure is associated with telomere length shortening in Chinese battery manufacturing plant workers
- High resolution telomere FISH analysis of testicular germ cell tumors reveals telomere anomalies specific to cancer subtypes and demonstrates telomere shortening as an early event in TGCT carcinogenesis
- Higher serum phenylalanine concentration is associated with more rapid telomere shortening in men
- Hostility and telomere shortening among US military veterans: Results from the National Health and Resilience in Veterans Study
- Hydroxyl radical‐induced apoptosis in human tumor cells is associated with telomere shortening but not telomerase inhibition and caspase activation
- Immortalization of human oral keratinocytes is associated with elevation of telomerase activity and shortening of telomere length.
- Immunosenescence and rheumatoid arthritis: does telomere shortening predict impending disease?
- Impact of telomere shortening on cell cycle progression and induction of senescence
- Impact of telomere shortening with Age in Stem Cell Therapy: New Strategies to Increase telomere Length
- Improved Methods for Analysis of Telomere-initiated Cellular Senescence and telomere shortening in Saccharomyces Cerevisiae
- In vitro proinflammatory gene expression predicts in vivo telomere shortening: A preliminary study
- In utero TNF‐α treatment induces telomere shortening in young adult mice in an ATF7‐dependent manner
- Increased expression of p21 in CD14+ human monocytes correlates with telomere shortening in ocular sarcoidosis patients
- Increased genomic alteration complexity and telomere shortening in B-CLL cells resistant to radiation-induced apoptosis
- Independent and Combined Effects of telomere shortening and mtDNA4977 Deletion on Long-term Outcomes of Patients with Coronary Artery Disease
- Induction of nitric oxide synthase-dependent telomere shortening after functional inhibition of Hsp90 in human tumor cells
- Induction of telomere shortening and cellular apoptosis by sodium meta-arsenite in human cancer cell lines
- Induction of telomere shortening and replicative senescence by cryopreservation
- Inflammatory response to acute mental stress is associated with altered cortisol reactivity and telomere shortening in patients with coronary artery disease
- Inhibition of 6A8 α-mannosidase gene expression resulted in telomere length shortening in nasopharyngeal carcinoma cell CNE-2L2
- Inhibition of human telomerase in immortal human cells leads to progressive telomere shortening and cell death
- Inhibition of microRNA-34a Protects against Aging and Progeria Associated Cardiac Dysfunction by Interfering with telomere shortening and DNA Damage …
- Inhibition of tankyrase 1 in human gastric cancer cells enhances telomere shortening by telomerase inhibitors
- INSULIN RESISTANCE DETERMINES telomere shortening IN PHAGOCYTIC CELLS FROM METABOLIC SYNDROME PATIENTS. INVOLVEMENT OF …
- Intramitotic and intraclonal variation in proliferative potential of human diploid cells: explained by telomere shortening
- Inula Viscosa Extracts Induces telomere shortening and Apoptosis in Cancer Cells and Overcome Drug Resistance
- Investigation of telomere shortening caused by dyskeratosis congenita-associated heterozygous TIN2 mutations
- Ionizing radiation-induced gene modulations, cytokine content changes and telomere shortening in mouse fetuses exhibiting forelimb defects
- iPSC modeling of severe aplastic anemia reveals impaired differentiation and telomere shortening in blood progenitors
- Irreversible cellular senescence induced by prolonged exposure to H2O2 involves DNA-damage-and-repair genes and telomere shortening
- Irreversible telomere shortening by 3′-azido-2′, 3′-dideoxythymidine (AZT) treatment
- Is telomere Length shortening a Predictive Biomarker for Cancer Risk in Ulcerative Colitis?
- Is telomere shortening Related to Progeria?
- Is telomere shortening reversible? A clue from NASA’s Twin study.
- Knockdown of homeobox containing 1 increases the radiosensitivity of cervical cancer cells through telomere shortening
- Lack of age‐associated telomere shortening in long‐and short‐lived species of sea urchins
- Lack of telomerase causes telomere shortening in RA
- Lack of telomere shortening during senescence in Paramecium.
- Lack of telomere shortening with age in mouse resting zone chondrocytes
- Lactobacilli modulated AMPK activity and prevented telomere shortening in ageing rats
- L-carnosine reduces telomere damage and shortening rate in cultured normal fibroblasts
- Leucocyte telomere shortening in relation to newly diagnosed type 2 diabetic patients with depression
- Leucocyte telomere shortening is associated with nonalcoholic fatty liver disease‐related advanced fibrosis
- Leukocyte telomere Length Shortening and Alzheimer’s Disease Etiology
- Leukocyte telomere Length Shortening, hTERT Genetic Polymorphisms and Risk of Childhood Acute Lymphoblastic Leukemia
- Leukocyte telomere shortening in elderly Type2DM patients with previous myocardial infarction
- Leukocyte telomere shortening in grown-up patients with congenital heart disease
- Leukocyte telomere shortening in Huntington’s disease
- Leukocyte telomere shortening in staff working in cardiac catheterization laboratory
- Lifetime pesticide use and telomere shortening among male pesticide applicators in the Agricultural Health Study
- Limited telomere shortening in hematopoietic stem cells after transplantation
- Lineage-specific telomere shortening and unaltered capacity for telomerase expression in human T and B lymphocytes with age
- Lipid peroxidation-mediated telomere shortening in hydroxyl radical-induced apoptosis in HeLa cells
- Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
- Longitudinal associations between metabolic syndrome components and telomere shortening
- Longitudinal telomere length shortening and cognitive and physical decline in later life: The Lothian Birth Cohorts 1936 and 1921
- Longitudinal telomere shortening and early Alzheimer’s disease progression in adults with down syndrome
- Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule
- Long‐term follow‐up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic stem …
- Long-term lymphoma survivors following high-dose chemotherapy and autograft: evidence of permanent telomere shortening in myeloid cells, associated with marked …
- Lower antioxidant capacity and elevated p53 and p21 may be a link between gender disparity in renal telomere shortening, albuminuria, and longevity
- LSC Abstract–Increased oxidative stress leads to telomere shortening in children with alpha-1 antitrypsin deficiency
- Luminal and cancer cells in the breast show more rapid telomere shortening than myoepithelial cells and fibroblasts
- Lung alveolar integrity is compromised by telomere shortening in telomerase-null mice
- Lung function and telomere shortening in blood leukocytes in clean-up workers of Chornobyl NPP suffered of COPD
- Mammalian telomere dynamics: healing, fragmentation shortening and stabilization
- Marked telomere shortening in mobilized peripheral blood progenitor cells (PBPC) following two tightly spaced high-dose chemotherapy courses with G-CSF
- Markers of cellular senescence. telomere shortening as a marker of cellular senescence
- Maternal smoking hastens telomere shortening in neonatal umbilical cord blood leukocytes
- Maternal‐fetal cross talk through cell‐free fetal DNA, telomere shortening, microchimerism, and inflammation
- Mathematical modeling confirms the length-dependency of telomere shortening
- Mathematical modeling of telomere shortening: an overview
- Mathematical modeling of vascular endothelial layer maintenance: the role of endothelial cell division, progenitor cell homing, and telomere shortening
- Mathematical Models and Computer Simulations of telomere shortening
- Mean leukocyte telomere length shortening and type 2 diabetes mellitus: a case-control study
- Measurement of telomere length in cells from pleural effusion: Asbestos exposure causes telomere shortening in pleural mesothelial cells
- Mechanism of acridine-based telomerase inhibition and telomere shortening
- Mechanism of p53 Accumulation and Activation by Ionizing Radiation and telomere shortening
- Mechanism of telomere shortening by oxidative stress
- Mechanism of telomere shortening in photoaging model induced by 8-methoxypsoralen and ultraviolet A
- Mechanisms of breast cancer risk in shift workers: association of telomere shortening with the duration and intensity of night work
- Mechanisms of telomere shortening in placentas from pregnancies complicated with intrauterine growth restriction
- Medaka fish exhibits longevity gender gap, a natural drop in estrogen and telomere shortening during aging: a unique model for studying sex-dependent …
- Microbiota and telomere shortening in gut-lung axis of human immunodeficiency virus infected donors
- Minimal Shortening of Leukocyte telomere Length Across Age Groups in a Cross-Sectional Study for Carriers of a Longevity-Associated FOXO3 Allele
- Mitogen stimulation cooperates with telomere shortening to activate DNA damage responses and senescence signaling
- MitoQ counteracts telomere shortening and elongates lifespan of fibroblasts under mild oxidative stress
- Modeling of the Process of telomere shortening: an Overview
- Modelling telomere shortening and the role of oxidative stress
- Moderate stem-cell telomere shortening rate postpones cancer onset in a stochastic model
- Monocyte telomere shortening and oxidative DNA damage in type 2 diabetes
- Mutated telomeres sensitize tumor cells to anticancer drugs independently of telomere shortening and mechanisms of telomere maintenance
- Mutations in XLF/NHEJ1/Cernunnos gene results in downregulation of telomerase genes expression and telomere shortening
- Nanoparticle mediated delivery of 2′-O-methyl-RNA leads to efficient telomerase inhibition and telomere shortening in human lung cancer cells
- Nestling telomere shortening, but not telomere length, reflects developmental stress and predicts survival in wild birds
- Neural Correlates and Peripheral miRNAs Associated with Stress-Related telomere shortening
- No evidence of substantia nigra telomere shortening in Parkinson’s disease
- No telomere shortening in marrow stroma from patients with MDS
- Nonmyeloablative conditioning does not prevent telomere shortening after allogeneic stem cell transplantation
- Novel and potent telomerase antagonist (GRN163L) inhibits telomerase activity, resulting in telomere shortening and apoptosis of multiple myeloma cells
- Novel biomolecules of ageing, sex differences and potential underlying mechanisms of telomere shortening in coronary artery disease
- Nutrition, oxidative damage, telomere shortening, and cellular senescence: individual or connected agents of aging?
- On telomere shortening in soft-tissue tumors
- On the origin of Robertsonian fusions in nature: evidence of telomere shortening in wild house mice
- OP20 Hepatocytes and cholangiocytes do not have significant telomere shortening with increasing chronological age in normal livers
- Organization of telomere sequences in birds: evidence for arrays of extreme length and for in vivo shortening
- Osteoarthritis and telomere shortening
- Oxidative DNA damage and telomere shortening
- Oxidative stress and telomere shortening in normal human fibroblasts after ir-radiation with X-rays
- Oxidative stress, telomere shortening, and DNA methylation in relation to low‐to‐moderate occupational exposure to welding fumes
- Oxidative stress‐induced renal telomere shortening as a mechanism of cyclosporine‐induced nephrotoxicity
- Oxidative stress-induced telomere length shortening of circulating leukocyte in patients with obstructive sleep apnea
- P-039: telomere shortening and/or “absence” may indicate dementia/AD status in older individuals with down syndrome
- P3995Advanced glycation end-products and telomere shortening contribute to cardiac aging: the relationship with myocardial strain
- P838Expression of miR-23a induces leukocyte telomere shortening and is associated with poor clinical outcomes in patients with coronary artery disease
- Parallel telomere shortening in multiple body tissues owing to malaria infection
- Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening
- Pharmacodynamics of telomerase inhibition and telomere shortening by noncytotoxic suramin
- Phosphorylation of telomeric repeat binding factor 1 (TRF1) by Akt causes telomere shortening
- Placental Ageing in Adverse Pregnancy Outcomes: telomere shortening, Cell Senescence, and Mitochondrial Dysfunction
- Placental telomere shortening in stillbirth: a sign of premature senescence?
- Platinum (II) phenanthroimidazole G-quadruplex ligand induces selective telomere shortening in A549 cancer cells
- Poor maternal nutrition followed by accelerated postnatal growth leads to telomere shortening and increased markers of cell senescence in rat islets
- Potential CO2 effects on telomere shortening in Porites lutea & Method improvements for telomere assessment in corals
- Predictive factors and prognostic effect of telomere shortening in pulmonary fibrosis
- Premature telomere shortening and impaired regenerative response in hepatocytes of individuals with NAFLD
- Premature telomere shortening in polymorphonuclear neutrophils from patients with systemic lupus erythematosus is related to the lupus disease activity
- Prevalence of telomere shortening in familial and sporadic pulmonary fibrosis is increased in men
- Prevention of critical telomere shortening by oestradiol in human normal hepatic cultured cells and carbon tetrachloride induced rat liver fibrosis
- Prevention of Radiation-Induced telomere shortening, A Novel Mechanism Underlying Low-Dose Arsenic-Mediated Protection of Normal T-Lymphocytes
- Prevention Of telomere shortening
- Pro12Ala Polymorphism of the PPARγ2 Gene Interacts With a Mediterranean Diet to Prevent telomere shortening in the PREDIMED-NAVARRA Randomized Trial
- Progressive telomere shortening and telomerase reactivation during hepatocellular carcinogenesis
- Progressive telomere shortening is part of the natural history of chronic lymphocytic leukaemia and impacts clinical outcome: evidences from long term follow-up.
- Progressive telomere shortening occurs in cultured rat microglia, but not astrocytes
- Progressive telomere shortening of Epstein-Barr virus-specific memory T cells during HIV infection: contributor to exhaustion?
- Prostate stromal cell telomere shortening is associated with risk of prostate cancer in the placebo arm of the Prostate Cancer Prevention Trial
- Proteomic and microRNA data clarifying the effects of telomere shortening on cancer cells
- Proximity to roads, but not exposure to metal pollution, is associated with accelerated developmental telomere shortening in nestling great tits
- Race-related health disparities and biological aging: does rate of telomere shortening differ across blacks and whites?
- Radiation and chemotherapy bystander effects induce early genomic instability events: telomere shortening and bridge formation coupled with mitochondrial …
- Radiation-induced senescence-like growth arrest requires TP53 function but not telomere shortening
- Radiobiological effectiveness of ultrashort laser-driven Electron bunches: micronucleus frequency, telomere shortening and cell viability
- Rapid telomere shortening in children
- Rate of telomere shortening and cardiovascular damage: a longitudinal study in the 1946 British Birth Cohort
- RATE OF telomere shortening AND CARDIOVASCULAR PHENOTYPES
- Rate of telomere shortening and metabolic and cardiovascular risk factors: A longitudinal study in the 1934–44 Helsinki Birth Cohort Study
- Recent advances of Blood telomere length (BTL) shortening: A potential biomarker for development of cancer
- Relationship between microsatellite instability and telomere shortening in colorectal cancer
- Relationship between spontaneous or radiation-induced apoptosis and telomere shortening in G0 human lymphocytes
- Relationship between telomere shortening, genetic instability, and site of tumour origin in colorectal cancers
- Renal failure induces telomere shortening in the rat heart
- Replicative senescence as a model of aging: the role of oxidative stress and telomere shortening–an overview
- Replicative senescence of hematopoietic stem cells during serial transplantation: does telomere shortening play a role?
- Replicative senescence, telomere shortening and cell proliferation rate in Gaddi goat’s skin fibroblast cell line
- Resistance to senescence induction and telomere shortening by a G-quadruplex ligand inhibitor of telomerase
- Response to comments on is telomere shortening reversible? A clue from NASA’s twins mission
- Reversibility of defective hematopoiesis caused by telomere shortening in telomerase knockout mice
- Revisiting telomere shortening in Cancer
- Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells
- Robertsonian translocation as a result of telomere shortening during replicative senescence and immortalization of bovine oviduct epithelial cells
- Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping
- Role of cell‐cycle turnover and oxidative stress in telomere shortening and cellular senescence in patients with chronic hepatitis C
- Role of Oxidative DNA Damage in telomere shortening and Cellular Aging
- Role of oxidative stress in telomere shortening in cultured fibroblasts from normal individuals and patients with ataxia–telangiectasia
- Role of shelterin proteins for telomere shortening in chronic lymphocytic leukemia
- Saccharomyces cerevisiae as a model to study replicative senescence triggered by telomere shortening
- Senescence and chromosomal instability induced by telomere shortening affect liver regeneration and hepatocarcinogenesis
- Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines
- Senescence occurs with hTERT repression and limited telomere shortening in human oral keratinocytes cultured with feeder cells
- Senescence, telomere shortening and telomere maintenance
- Sepsis induces telomere shortening: a potential mechanism responsible for delayed pathophysiological events in sepsis survivors?
- Sex-dependent telomere shortening, telomerase activity and oxidative damage in marine medaka Oryzias melastigma during aging
- Shortening of telomere length by metabolic factors in diabetes: protective effects of fenofibrate
- Shortening telomere is associated with subclinical atherosclerosis biomarker in omnivorous but not in vegetarian healthy men
- Significant telomere shortening in acute and chronic leukemia
- Significant telomere shortening in childhood leukemia
- Site‐specific DNA damage at GGG sequence by oxidative stress may accelerate telomere shortening
- Site-specific DNA damage at the GGG sequence by UVA involves acceleration of telomere shortening
- Six-year telomere shortening
