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      Ursolic Acid
      January 15, 2020
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      Zerumbone
      January 15, 2020

       

      Withaferin A (Ashwaganda)

      1. 2, 3-Dihydro-3β-methoxy Withaferin-A Protects Normal Cells against Stress: Molecular Evidence of Its Potent Cytoprotective Activity
      2. 2, 3-Dihydrowithaferin A-3β-O-sulfate, a new potential prodrug of withaferin A from aeroponically grown Withania somnifera
      3. 3beta-methoxy derivation of Withaferin-a Attenuates its Anticancer potency: Bioinformatics and molecular evidences
      4. 5,6-De-epoxy-5-en-7-one-17-hydroxy withaferin A, a new cytotoxic steroid from Withania somnifera L. Dunal leaves
      5. A novel combination of withaferin A and sorafenib shows synergistic efficacy against both papillary and anaplastic thyroid cancers
      6. A novel combination of withaferin A and sulforaphane inhibits epigenetic machinery, cellular viability and induces apoptosis of breast cancer cells
      7. A rapid and simple high performance thin layer chromatographic method for simultaneous analysis of β-sitosterol-D-glucoside, gallic acid, withaferin A and withanolide A in Ashvagandharishta
      8. A Study on the efficacy of Withaferin-A in reducing oxidative stress against DEN induced hepatocellular carcinoma
      9. A validated and densitometric HPTLC method for the quantification of Withaferin-A and Withanolide-A in different plant parts of two morphotypes of Withania somnifera
      10. A110 THORACIC CANCERS: PATHOGENESIS AND NOVEL TARGETS: The Use Of Withaferin-A As An Anti-Metastatic Agent In Non-Small Cell Lung Cancer
      11. Abstract A10: Withaferin-A, a natural compound inhibits AKT-induced metastatic colorectal cancer
      12. Abstract A115: withaferin A downregulates her-2/neu protein expression in human breast cancer cells.
      13. Abstract A2-32: Identification of withaferin A as a novel cancer stem cell inhibitor to overcome drug resistance in non-small cell lung carcinoma
      14. Abstract A29: Targeting adenylate kinase-4 modulation of HIF-1α: Stability identifies Withaferin-A suppresses lung cancer metastasis
      15. Abstract A4: withaferin A induces apoptosis in imatinib-resistant CML cells by repressing the Akt signaling pathway
      16. Abstract A48: Ovarian tumor-induced immunosuppression of NK cells and its prevention by dietary supplementation of herbal withaferin A (Ashwagandha).
      17. Abstract B41: withaferin A promotes ROS-mediated differentiation of neuroblastoma
      18. Abstract B57: A natural plant-derived compound, withaferin A, exploits the stress pathway to induce antitumor immunity.
      19. Abstract B84: Withaferin‐A is a novel HSF‐1 inhibitor with potent antitumor effects in melanoma in vivo
      20. Abstract C218: Novel therapeutic potential in targeting micro tubules by naturally occurring anti cancer agent withaferin A in human cancers.
      21. Abstract LB-113: A novel role of withaferin A as an effective pro-apoptotic receptor agonist (PARA) and insights into the underlying molecular mechanisms
      22. Abstract LB-154: Epigenetic silencing of triple-negative breast cancer hallmarks by withaferin A
      23. Abstract NTOC-100: OVARIAN TUMOR-ASSOCIATED GRP78 INDUCES IMMUNOSUPPRESSION AND withaferin A (ASHWAGANDHA) ENHANCES ANTI …
      24. Abstract P2-09-12: withaferin A-mediated inhibition of breast carcinoma involves concomitant activation of CHOP and Elk1 via ERK/ribosomal S6 kinase (RSK) …
      25. Abstract# 3903: Inhibition of human cervical cancer cell growth by withaferin A and potential mechanisms
      26. Actin microfilament aggregation induced by withaferin A is mediated by annexin II
      27. Activation of signal transducer and activator of transcription 3 fails to confer resistance against withaferin A-induced apoptosis in human breast cancer cells
      28. Age related differences in stress-induced neurobehavioral patterns in rats modulated by withaferin-A and other antioxidants
      29. Agrobacterium rhizogenes mediated hairy root culture system of Withania somnifera L Dunal for withaferin A production
      30. Ameliorative effect of withaferin A on ageing-mediated impairment in the dopamine system and its associated behavior of Wistar Albino Rat
      31. An adaptogen: withaferin A ameliorates in vitro and in vivo pulmonary fibrosis by modulating the interplay of fibrotic, matricelluar proteins, and cytokines
      32. An analog of withaferin A activates the MAPK and glutathione “stress” pathways and inhibits pancreatic cancer cell proliferation
      33. Anti-cancer activity of withaferin A in B-cell lymphoma
      34. Anti-cancer Effects and Molecular Mechanisms of withaferin A
      35. Anticancer Effects of withaferin A in Head and Neck Squamous Cell Carcinomas through Modulation of Heat Shock Protein Expression
      36. Anticancer effects of withaferin A on UP-LN1 carcinoma cells through the inhibition of STAT3 phosphorylation and IFN-γ-mediated induction of metastatic cancer stem …
      37. Anti-cancer Mechanisms of the Natural Plant Derived Compound, withaferin A in HER-2/neu Breast Cancer
      38. Anti-inflammatory effect of withaferin A on dopaminergic neuron of aged rat.
      39. Anti-inflammatory effects of withaferin A in islet transplantation and pancreatitis.
      40. Antiplatelet, anticoagulant, and profibrinolytic activities of withaferin A
      41. Antiproliferation potential of withaferin A on human osteosarcoma cells via the inhibition of G2/M checkpoint proteins
      42. Antitumor and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma in vivo
      43. Apoptosis induction by ayurvedic medicine constituent withaferin A in human breast cancer cells is mediated by reactive oxygen species-dependent activation of Bak
      44. Apoptosis is induced in leishmanial cells by a novel protein kinase inhibitor withaferin A and is facilitated by apoptotic topoisomerase I–DNA complex
      45. AshwaMAX and withaferin A inhibits gliomas in cellular and murine orthotopic models
      46. Assessment of hepatoprotective and nephroprotective potential of withaferin A on bromobenzene-induced injury in Swiss albino mice: possible involvement of …
      47. Assessment of the Immune Status in “withaferin A” Treated Rats in Experimental Mammary Carcinogenesis by Flow Cytometry
      48. Astaxanthin and withaferin A block paracrine cytokine interactions between UVB-exposed human keratinocytes and human melanocytes via the attenuation of …
      49. Autophagy fails to alter withaferin A-mediated lethality in human breast cancer cells
      50. Axl is a novel target of withaferin A in the induction of apoptosis and the suppression of invasion
      51. Ayurvedic medicine constituent withaferin A causes G2 and M phase cell cycle arrest in human breast cancer cells
      52. Barrier protective effects of withaferin A in HMGB1-induced inflammatory responses in both cellular and animal models
      53. Biomass production and withaferin A synthesis by Withania somnifera grown in aeroponics and hydroponics
      54. Biosynthesis of Withanolides in Acnistus breviflorus Chemical Degradation of 14C-Labelled Jaborosalactone A and withaferin A
      55. Biotransformation of withaferin-a by a culture ofArthrobacter simplex
      56. Broad-spectrum antitumor properties of withaferin A: a proteomic perspective
      57. Carbohydrate and elicitor enhanced withanolide (withaferin A and withanolide A) accumulation in hairy root cultures of Withania somnifera (L.)
      58. Characterizing withaferin A as a novel NRF2 inducer: implications for liver disease prevention
      59. CHEMICAL PROFILING FOR FEW PLANT METABOLITES (WITHANOLIDE-A AND WITHAFERIN-A) INCLUDING ANTI-CANCER COMPOUNDS IN FOREST SPECIES …
      60. Chemistry of withaferin-A: chemo, regio, and stereoselective synthesis of novel spiro-pyrrolizidino-oxindole adducts of withaferin-A via one-pot three-component [3+ 2] …
      61. Chemo prevention effect of withaferin A, a natural compound, on mouse models of colorectal carcinogenesis
      62. Chemopreventive and chemotherapeutic effect of Withaferin-A on in vivo models of prostate cancer
      63. Chemotherapeutic effect of withaferin A in human oral cancer cells
      64. CHEMOTHERAPEUTIC EFFICACY OF WITHAFERIN-A IN EXPERIMENTAL HEPATOCELLULAR CARCINOMA
      65. Circadian time-dependent chemopreventive potential of withaferin-A in 7, 12-dimethyl-benz [a] anthracene-induced oral carcinogenesis
      66. Combination of withaferin A and X-ray irradiation enhances apoptosis in U937 cells
      67. Combination strategies for management of ovarian cancer using doxorubicin and withaferin A
      68. Combinatorial withaferin A and Sulforaphane and Their Potential Roles in Breast Cancer Prevention and Therapy
      69. Comparison of the Protective Effect of Withaferin-‘A’and Hydrocortisone against CCL~ 4 induced Hepatotoxicity in Rats
      70. Concomitant activation of ETS-like transcription factor-1 and Death Receptor-5 via extracellular signal-regulated kinase in withaferin A-mediated inhibition of …
      71. Concomitant Inhibition of Cytoprotective Autophagy Augments the Efficacy of withaferin A in Hepatocellular Carcinoma
      72. Constituents of Withania somnifera Dun. III. The Side Chain of withaferin A*,1
      73. Constituents of Withania somnifera Dun. Part IV. The structure of withaferin A
      74. Constituents of Withania somnifera Dun. Part VI. The stereochemistry of withaferin A
      75. Constituents of Withania somnifera Dun. Part VII. Rearrangements in withaferin A
      76. Constituents of Withania somnifera Dun. Part VIII. A new steroidal lactone, 27-deoxy-14-hydroxy-withaferin A
      77. Correction: withaferin A Inhibits the Proteasome Activity in Mesothelioma In Vitro and In Vivo
      78. Cytotoxicity of Ashwagandha Derived withaferin A to Human Cancer Cells: Molecular Insights into the Response of Telomerase Plus and Minus Cell
      79. Cytotoxicity of Phytocompounds Cannabigerol (CBG) and withaferin A to SKOV3 Ovarian Cancer Cells
      80. Cytotoxicity of withaferin A in glioblastomas involves induction of an oxidative stress-mediated heat shock response while altering Akt/mTOR and MAPK signaling …
      81. Data from SILAC-based quantitative analysis of lysates from mouse microglial cells treated with withaferin A (WA)
      82. DD-03THE NATURALLY OCCURRING STEROID, withaferin A, IN SYNERGISTIC CONCERT WITH HER2/EGFR INHIBITORS ABROGATES PROLIFERATION OF …
      83. DDEL-04 AshwaMAX and withaferin A inhibits gliomas in cellular and murine orthotopic models
      84. Ddis-15. Synergistic Inhibition Of Glioma Cell Proliferation By withaferin A And Tumor Treating Fields
      85. Determination of withaferin A and withanolide A in mice plasma using high-performance liquid chromatography-tandem mass spectrometry: application to …
      86. DETERMINATION OF withaferin A CONTENT OF ROOT, STEM AND LEAF EXTRACTS OF WITHANIA SOMNIFERA (L) DUNAL COLLECTED IN KENYA
      87. Determination of Withaferin-A in two Withania Species by RP-HPLC method
      88. Development and optimization of hairy root culture systems in Withania somnifera (L.) Dunal for withaferin-Aproduction
      89. Development of a goat model for evaluation of withaferin A: Cervical implants for the treatment of cervical intraepithelial neoplasia
      90. Development of a new method for identification and estimation of Withania somnifera root, and a method for quantitative analysis of withaferin A in young and old …
      91. Development of HPTLC fingerprint by simultaneous estimation of Ashwagandha (withaferin-A) and Glycyrrhiza (18-β-glycyrrhetinic acid) in some polyherbal over the …
      92. DEVELOPMENT OF VALIDATED RP-HPLC METHOD FOR THE ESTIMATION OF WITHAFERIN-A IN WITHANIA SOMNIFERA, Its EXTRACT AND POLYHERBAL …
      93. Development of withaferin A analogs as probes of angiogenesis
      94. Different effects of 4β-hydroxywithanolide E and withaferin A, two withanolides from Solanaceae plants, on the Akt signaling pathway in human breast cancer cells
      95. Differential activities of the two closely related withanolides, withaferin A and Withanone: bioinformatics and experimental evidences
      96. Differential chemosensitization of P-glycoprotein overexpressing K562/Adr cells by withaferin A and Siamois polyphenols
      97. Differential effect of withaferin A treatment on activation of Notch1 and Notch2 in human breast cancer cells.
      98. Disease subtype independent biomarkers of breast cancer prevention by withaferin A
      99. Disease Subtype–Independent Biomarkers of Breast Cancer Chemoprevention by the Ayurvedic Medicine Phytochemical withaferin A
      100. Down-regulation of estrogen receptor-alpha and rearranged during transfection tyrosine kinase is associated with withaferin A-induced apoptosis in MCF-7 …
      101. DOXIL when combined with withaferin A (WFA) targets ALDH1 positive cancer stem cells in ovarian cancer
      102. Drug carrier for sustained release of withaferin A for pancreatic cancer treatment
      103. Dual Elicitation for Improved Production of withaferin A by Cell Suspension Cultures of Withania somnifera
      104. Early-stage treatment with withaferin A reduces levels of misfolded superoxide dismutase 1 and extends lifespan in a mouse model of amyotrophic lateral …
      105. Effect of a radiosensitiser, withaferin A, on the free radical metabolising enzymes of neutrophils, in carcinoma of uterine cervix subjected to radiotherapy
      106. Effect of rhizobacterial inoculation on withaferin-a content of ashwagandha (var. Jawahar 20) roots.
      107. Effect of withaferin A on A549 cellular proliferation and apoptosis in non-small cell lung cancer
      108. Effect of withaferin A on cells in tissue culture
      109. Effect of withaferin A on Ehrlich ascites tumor cells. II. Target tumor cell destruction in vivo by immune activation
      110. Effect of withaferin A on Ehrlich ascites tumor cells—cytological observations
      111. Effect of withaferin A on the development and decay of thermotolerance in B16F1 melanoma: A preliminary study
      112. Effect of withaferin, a radiosensitizer, on the erythrocyte antioxid-ants in carcinoma of uterine cervix
      113. Effects of dietary compounds sulforaphane and withaferin A on MCF-7 breast cancer cells
      114. Effects of withaferin A on Mouse Models of Alexander Disease
      115. Efficacy of Withania somnifera chemotypes NMITLI – 101R, 118R and withaferin A against experimental visceral leishmaniasis
      116. Elicitation of withaferin-A in hairy root culture of Withania somnifera (L.) Dunal using natural polysaccharides
      117. Elucidating Anticancer Activity of withaferin A, Major Constituent of Withania somnifera Through Suppression of NF-кB, a Prominent Marker in Cancer
      118. Elucidation of molecular mechanism of butyrate and withaferin A induced antiangiogenesis and apoptosis
      119. Endoplasmic reticulum stress mediates withaferin A-induced apoptosis in human renal carcinoma cells
      120. Enhanced activity of chemotherapeutic drugs by blueberry anthocyanidins and withaferin A against human lung cancer cells.
      121. Enhanced bioproduction of withaferin A from suspension cultures of Withania somnifera.
      122. Enhanced production of withaferin-A in shoot cultures of Withania somnifera (L) Dunal
      123. Enhancement of radiation induced cell death in chicken B lymphocytes by withaferin A
      124. Enhancement of the response of B16F1 melanoma to fractionated radiotherapy and prolongation of survival by withaferin A and/or hyperthermia
      125. Epigenetic silencing of triple negative breast cancer hallmarks by withaferin A
      126. ERBB2 overexpression establishes ERBB3-dependent hypersensitivity of breast cancer cells to withaferin A
      127. ET-71 the antitumor effects of withaferin A in glioblastoma stem cells
      128. Evaluation of analgesic, antipyretic and ulcerogenic effect of withaferin A
      129. EVALUATION OF IN VITRO withaferin A PRODUCTION FROM WITHANIA COAGULANS (STOCKS) DUNAL
      130. EVALUATION OF withaferin A CONTENT IN DIFFERENT ACCESSIONS AND IN IN VITRO CULTURES OF WITHANIA COAGULANS (STOCKS) DUNAL
      131. Evaluation of withaferin A content in different accessions and in in vitro cultures of Withania coagulans (Stocks) Dunal.
      132. Evaluation of withaferin-A and analogues as antibacterial agents: Structure-activity relationship study
      133. Examination of the effect of the natural plant extract, withaferin A, on heat shock protein gene expression in Xenopus laevis A6 cells
      134. Examination of the effect of withaferin A on heat shock protein gene expression in Xenopus laevis A6 kidney epithelial cells
      135. Expanding the Chemical Space of withaferin A by Incorporating Silicon to Improve its Clinical Potential on Human Ovarian Carcinoma Cells
      136. Exploring the inhibitory activity of Withaferin-A against Pteridine reductase-1 of L. donovani
      137. Extraction and Isolation of withaferin A (Steroidal Lactone) from Withania Somnifera Leafs and it’s TLC and HPLC Analysis.
      138. Extraction Optimization for Phenolic- and Withanolide-Rich Fractions from Withania somnifera Roots: Identification and Quantification of withaferin A, 12-Deoxywithastromonolide, and Withanolide A in Plant Materials and Marketed Formulations Using a Reversed-Phase HPLC–Photodiode Array Detection Method
      139. FORMULATION AND EVALUATION OF SELF-NANO EMULSIFYING DRUG DELIVERY SYSTEM FOR SOLUBILITY AND BIOAVAILABILITY ENHANCEMENT OF POORLY WATER SOLUBLE withaferin A
      140. Genetic and withaferin A Analysis of Iranian Natural Populations of Withania Somnifera and W. Coagulans by RAPD and HPTLC
      141. Glucose metabolism‐targeted therapy and withaferin A are effective for epidermal growth factor receptor tyrosine kinase inhibitor‐induced drug‐tolerant persisters
      142. Growth arrest by the antitumor steroidal lactone withaferin A in human breast cancer cells is associated with down-regulation and covalent binding at cysteine 303 of β …
      143. Growth inhibitory effects of withaferin A on MDS-L cells–A human 5q Myelodysplastic Syndrome (MDS) cell line
      144. High performance thin layer chromatography method for simultaneous estimation of vicine, trigonelline and withaferin A in a polyherbal antidiabetic formulation
      145. Homology modelling, molecular docking, and molecular dynamics simulations reveal the inhibition of Leishmania donovani dihydrofolate reductase-thymidylate synthase enzyme by Withaferin-A
      146. HPLC analysis of withaferin A in Withania somnifera (L.) Dunal
      147. HPTLC method for analysis of withaferin-A in Ashwagandha (Withania somnifera)
      148. Hsp90/Cdc37 chaperone/co-chaperone complex, a novel junction anticancer target elucidated by the mode of action of herbal drug withaferin A
      149. Hypothalamic ATP Has a Crucial Role in the Pathogenesis of Leptin Resistance: A Potential Mechanism for the Amelioration of Leptin Resistance by Celastrol and withaferin A
      150. Identification and quantitative analysis of cellular proteins affected by treatment with withaferin A using a SILAC-based proteomics approach
      151. Identification of Biological Targets of the Angiogenic Agent withaferin A
      152. Identification of withaferin A as a potential candidate for anti-cancer therapy in non-small cell lung cancer
      153. Imaging withaferin A-Vimentin Interactions in Live Cells and Fibrotic Tissues
      154. Immunosuppressive activity of two plant steroidal lactones withaferin A and withanolide E.
      155. Impeding the single-strand annealing pathway of DNA double-strand break repair by withaferin A-mediated FANCA degradation
      156. In Vitro and In Vivo Cytotoxic Effects of withaferin A on Retinal Epithelial Pigmented Cells
      157. In vitro propagation and withaferin A production in Withania ashwagandha, a rare medicinal plant of India
      158. IN VITRO withaferin A PRODUCTION BY WITHANIA SOMNIFERA SUSPENSION CULTURE
      159. In vivo growth inhibitory and radiosensitizing effects of withaferin A on mouse Ehrlich ascites carcinoma
      160. Increase of withaferin And a glutathione contents of Withania somnifera (L.) Dun. shoots cultivated in vitro on medium supplemented with Zn*[2+
      161. Increased production of withanolide A, withanone, and withaferin A in hairy root cultures of Withania somnifera (L.) Dunal elicited with methyl jasmonate and salicylic …
      162. INCREASING BIOMASS ACCUMULATION AND withaferin A PRODUCTION IN CELL SUSPENSION CULTURE OF WITHANIA SOMNIFERA
      163. Induction of apoptosis by withaferin A in human leukemia U937 cells through down-regulation of Akt phosphorylation
      164. Inhibition of cell growth and induction of apoptosis in ovarian carcinoma cell lines CaOV3 and SKOV3 by natural withanolide withaferin A
      165. Inhibition of inflammatory cytokine-induced response in human islet cells by withaferin A
      166. Inhibition of monosodium urate crystal-induced inflammation by withaferin A
      167. Inhibition of NFκB by the natural product withaferin A in cellular models of Cystic Fibrosis inflammation
      168. Inhibition of the NEMO/IKKβ association complex formation, a novel mechanism associated with the NF-κB activation suppression by Withania somnifera’s key metabolite withaferin A
      169. Inhibition of VEGF: a novel mechanism to control angiogenesis by Withania somnifera’s key metabolite withaferin A
      170. Inhibitory effect of withaferin A on Helicobacter pylori‑induced IL‑8 production and NF‑κB activation in gastric epithelial cells
      171. Insights from the predicted structural analysis of carborane substituted withaferin A with Indoleamine-2, 3-dioxygenase as a potent inhibitor
      172. Integrated In silico Docking and MoMA Simulation Approaches Reveal withaferin A, Withalongolides A and B as Potent Aldo-Keto Reductase (AKR) 1C3 …
      173. Interaction studies of Withania somnifera’s key metabolite withaferin A with different receptors associated with cardiovascular disease
      174. Investigation of the role of withaferin A derivative in modulating signaling pathways in transformed cancer cells for inhibition of invasion and metastasis
      175. ISOLATION AND CHARACTERIZATION OF WITHAFERIN-A FROM THE WITHANIA SOMNIFERA (ASHWAGANDHA)
      176. Isolation and identification of withaferin A (Steroidal Lactone) from Withania somnifera (Ashwagandha).
      177. Isolation of Withaferin-A from Withania Somnifera plant root and its effects on cancer rats
      178. Lack of the cytochrome P450 3A interaction of methanolic extract of Withania somnifera, withaferin A, Withanolide A and Withanoside IV
      179. L-Arginine abolishes the anxiolytic-like effect of withaferin A in the elevated plus-maze test in rats
      180. LC-MS/MS method for the quantification of withaferin-Ain plant extracts of Withania spp.
      181. Leaf ontogenic phase-related dynamics of withaferin A and withanone biogenesis in ashwagandha (Withania somnifera Dunal.)- an important medicinal herb
      182. Ligand based virtual screening to identify potential anti cancer ligands similar to withaferin A targeting indoleamine 2, 3-dioxygenase
      183. Lipopolysaccharides-stimulated macrophage products enhance withaferin A-induced apoptosis via activation of caspases and inhibition of NF-κB pathway in human …
      184. Liquid chromatography-tandem mass spectrometry to assess the pharmacokinetics and tissue distribution of withaferin A in rats
      185. Mammary cancer chemoprevention by withaferin A is accompanied by in vivo suppression of self-renewal of cancer stem cells
      186. Mechanistic elucidation of the antitumor properties of withaferin A in breast cancer
      187. Metabolic alterations in mammary cancer prevention by withaferin A in a clinically relevant mouse model
      188. Metabolomics and proteomics reveal inhibition of glycolysis in withaferin A-mediated prevention of mammary carcinogenesis in MMTV-neu mice.
      189. Microbial transformations of natural antitumor agents. 23. conversion of withaferin-A to 12β-and 15β-hydroxy derivatives of withaferin-A.
      190. Microbial transformations of natural antitumor agents. 7. 14-alpha-Hydroxylation of withaferin-A by Cunninghamella elegans (NRRL 1393)
      191. Microbiological and chemical dehydrogenation of withaferin A
      192. Mild Thio‐Diversification of Bioactive Natural Products. withaferin A: A Case study.
      193. Mitotic catastrophe and inhibition of growth of Castration Resistant Prostate Cancers by a dietary agent Withaferin-A.
      194. Molecular conformations. Part VI. The structure of withaferin A: X-ray analysis of withaferin A acetate p-bromobenzoate
      195. Molecular docking and dynamic simulation studies evidenced plausible immunotherapeutic anticancer property by withaferin A targeting indoleamine 2, 3 …
      196. Molecular insight in the multifunctional activities of withaferin A
      197. Molecular insights into cancer therapeutic effects of the dietary medicinal phytochemical withaferin A
      198. Molecular Insights Into Withaferin-A-Induced Senescence: Bioinformatics and Experimental Evidence to the Role of NFκB and CARF
      199. Molecular mechanisms of hyperthermia-induced apoptosis enhanced by withaferin A
      200. Molecular targets and mechanisms of cancer prevention and treatment by withaferin A, a naturally occurring steroidal lactone
      201. Myeloid-derived suppressor cell function is reduced by withaferin A, a potent and abundant component of Withania somnifera root extract
      202. Natural products triptolide, celastrol, and withaferin A inhibit the chaperone activity of peroxiredoxin I
      203. Natural withanolide withaferin A induces apoptosis in uveal melanoma cells by suppression of Akt and c-MET activation
      204. Neuroprotective Effect of CR-777, a Glutathione Derivative of withaferin A, Obtained through the Bioconversion of Withania somnifera (L.) Dunal Extract by the Fungus …
      205. Neuroprotective efficacy of withaferin A on aging mediated oxidative stress in striatum and Substantia nigra of wistar albino rat.
      206. Nf-κb-Dependent Inhibition of HIV-1 Transcription by withaferin A
      207. Niosomal withaferin A with better antitumor efficacy
      208. Nitrogen treatment enhances sterols and withaferin A through transcriptional activation of jasmonate pathway, WRKY transcription factors, and biosynthesis genes in …
      209. Non-nucleosidic inhibition of Herpes simplex virus DNA polymerase: mechanistic insights into the anti-herpetic mode of action of herbal drug withaferin A
      210. Notch-1 inhibition by Withaferin-A: a therapeutic target against colon carcinogenesis
      211. Novel cytotoxic and antitumor agents. IV. withaferin A: relation of its structure to the in vitro cytotoxic effects on P388 cells.
      212. Novel validated HPTLC method for estimation of withaferin A in polyherbal formulations
      213. On the action and mechanism of withaferin-A from Withania somnifera, a novel and potent melanin dispersing agent in frog melanophores
      214. Optimisation of a microwave‐assisted method for extracting withaferin A from Withania somnifera Dunal. using central composite design
      215. Optimization of Carbon Source for Hairy Root Growth and withaferin A and Withanone Production in Withania somnifera
      216. Oral administration of withaferin A inhibits carcinogenesis of prostate in TRAMP model
      217. Oral administration of Withaferin-A effectively suppresses prostate carcinogenesis in PTEN-Knockout mice
      218. Overexpression of microRNA-25 by withaferin A induces cyclooxygenase-2 expression in rabbit articular chondrocytes
      219. Oxidative cytotoxic agent withaferin A resensitizes temozolomide-resistant glioblastomas via MGMT depletion and induces apoptosis through Akt/mTOR pathway …
      220. Oxidative stress-induced JNK/AP-1 signaling is a major pathway involved in selective apoptosis of myelodysplastic syndrome cells by Withaferin-A
      221. Par‐4 dependent modulation of cellular β‐catenin by medicinal plant natural product derivative 3‐azido withaferin A
      222. Par-4-dependent apoptosis by the dietary compound withaferin A in prostate cancer cells
      223. Pathological Evaluation of Anti-Tumour Effects of withaferin A against Experimentally Induced Mammary Tumour in Rats
      224. PAWR-mediated suppression of BCL2 promotes switching of 3-azido withaferin A (3-AWA)-induced autophagy to apoptosis in prostate cancer cells
      225. Peptidyl‐prolyl cis/trans isomerase Pin1 regulates withaferin A‐mediated cell cycle arrest in human breast cancer cells
      226. Pharmacogenomic Analysis of Adenylate Kinase-4 Gene Expression Signature Identifies Withaferin-A as an Anti-Metastatic Agent in Non-Small Cell Lung Cancer
      227. Pharmacological and analytical aspects of withaferin A: A concise report of current scientific literature
      228. Pharmacological levels of withaferin A (Withania somnifera) trigger clinically relevant anticancer effects specific to triple negative breast cancer cells
      229. Pharmaological Control of Angiofibrosis by withaferin A
      230. Phytochemicals, withaferin A and carnosol, overcome pancreatic cancer stem cells as c-Met inhibitors
      231. Pin1 is a novel target of withaferin A, a mammary cancer chemopreventative steroidal lactone from Withania somnifera
      232. Piriformospora indica elicitation of withaferin A biosynthesis and biomass accumulation in cell suspension cultures of Withania somnifera
      233. PO-293 Withaferin-A: a candidate anti-tumour natural compound for non-small cell lung cancer and stem cells
      234. Possible nitric oxide modulation in protective effects of withaferin A against stress induced neurobehavioural changes
      235. Potent Anti-Fibrotic Activity of withaferin A in Ocular Injury Models
      236. Potential Angiopreventive Mode of Action of withaferin A
      237. Preliminary Study on the Synthesis of withaferin A.
      238. Prevention of articular cartilage degeneration in a rat model of monosodium iodoacetate induced osteoarthritis by oral treatment with withaferin A
      239. Prevention of mammary carcinogenesis and pulmonary metastasis by Ayurvedic medicine constituent withaferin A in a clinically-relevant transgenic mouse model.
      240. Preventive effects of withaferin A isolated from the leaves of an Indian medicinal plant Withania somnifera (L.): comparisons with 17-β-estradiol and alendronate
      241. Probing the anticancer mechanism of prospective herbal drug withaferin A on mammals: a case study on human and bovine proteasomes
      242. Production dynamics of withaferin A in Withania somnifera (L.) Dunal complex
      243. Production of reactive oxygen species by withaferin A causes loss of type collagen expression and COX-2 expression through the PI3K/Akt, p38, and JNK pathways in …
      244. Production of the Anticancer Compound withaferin A from Genetically Transformed Hairy Root Cultures of Withania Somnifera
      245. Production of withaferin A in shoot cultures of Withania somnifera
      246. Proinflammatory cytokines IL-6 and TNF-α increased telomerase activity through NF-κB/STAT1/STAT3 activation, and withaferin A inhibited the signaling in colorectal …
      247. Protection against cerebral infarction by withaferin A involves inhibition of neuronal apoptosis, activation of PI3K/Akt signaling pathway, and reduced intimal …
      248. Protective effect of Withaferin-A on micronucleus frequency and detoxication agents during experimental oral carcinogenesis
      249. Protective effect of Withaferin-A on tumour formation in 7, 12-dimethylbenz [a] anthracene induced oral carcinogenesis in hamsters
      250. Protective Effect Of Withania Somnifera And Its Active Component withaferin A In Bromobenzene Induced Hepato And Nephrotoxicity
      251. Protective role of withaferin‐A on 7, 12‐dimethylbenz (a) anthracene‐induced genotoxicity in bone marrow of Syrian golden hamsters
      252. Protective role of Withaferin-A on immunoexpression of p53 and bcl-2 in 7, 12-dimethylbenz (a) anthracene-induced experimental oral carcinogenesis
      253. Protective role of Withaferin-A on red blood cell integrity during 7, 12-dimethylbenz [a] anthracene induced oral carcinogenesis
      254. Proteomic characterization of withaferin A-targeted protein networks for the treatment of monoclonal myeloma gammopathies
      255. Quantification of withaferin-A and withanolide-A in diploid (n = 12) and tetraploid cytotypes (n = 24) of “Rassbhary”, Physalis angulata L
      256. Radiosensitization of a mouse melanoma by withaferin A: In vivo studies
      257. Radiosensitizing effect of withaferin A combined with hyperthermia on mouse fibrosarcoma and melanoma
      258. Rapid and sensitive method for determination of withaferin-A in human plasma by HPLC
      259. Reactions of withaferin-A with model biological nucleophiles
      260. Reactive oxygen species generation and mitochondrial dysfunction in the apoptotic cell death of human myeloid leukemia HL-60 cells by a dietary compound withaferin A with concomitant protection by N-acetyl cysteine
      261. Regiospecific Synthesis of Ring A Fused withaferin A Isoxazoline Analogues: Induction of Premature Senescence by W-2b in Proliferating Cancer Cells
      262. Relationship between chemical structure and antitumor activity of withaferin A analogues
      263. Response of a mouse fibrosarcoma to withaferin A and radiation
      264. Response Surface Optimization Of In Vitro Culture Medium For Enhanced Production Of The Therapeutically Important Secondary Metabolite–withaferin A
      265. Ring A structural modified derivatives of withaferin A and the evaluation of their cytotoxic potential
      266. Role of mitogen‐activated protein kinases and Mcl‐1 in apoptosis induction by withaferin A in human breast cancer cells
      267. Role of withaferin A as a Neuroprotectant against Beta Amyloid Induced Toxicity and associated mechanism
      268. RP-HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF WITHAFERIN-A IN RANGER CAPSULE
      269. Safety and Pharmacokinetics of Withaferin-A in advanced stage high grade Osteosarcoma: A phase I trial
      270. Safety assessment of Withania somnifera extract standardized for withaferin A: acute and sub-acute toxicity study
      271. Scientific Evidence for Anticancer Effects of Withania somnifera and Its Primary Bioactive Component withaferin A
      272. Selective cytotoxicity of non-small cell lung cancer cells by the withaferin A-fortified root extract of Ashwagandha involves differential cell-cycle arrest and …
      273. Semi-synthesis of a novel hybrid isoxazolidino withaferin via chemoselective and diastereoselective 1, 3-dipolar nitrone cycloaddition reaction
      274. Semi-synthetic approach of withaferin A: Related steroidal lactones as a potent anti proliferative agents
      275. Simultaneous estimation of guggulsterone E, guggulsterone Z, KBA, AKBA, withaferin A and 6-gingerol by using HPLC-DAD method from ariflex tablet …
      276. Simultaneous Estimation of Stigmasterol and withaferin A in Union Total Herbal Formulation Using Validated HPTLC Method
      277. Simultaneous Estimation of withaferin A and Z-Guggulsterone in Marketed Formulation by RP-HPLC
      278. Simultaneous High-Performance Thin-Layer Chromatographic Quantification of withaferin A and Withanolide A in Solanum nigrum L. “Black Nightshade”
      279. STAT3 inhibitory activity of structurally simplified withaferin A analogues
      280. Stress induced somatic embryogenesis: an alternative technique to enhance production of withaferin A in Indian ginseng (Withania somnifera L.) Dunal
      281. Structure-based design of new analogs of withaferin A as antitumor agents
      282. Structure-based design, synthesis, and biological evaluation of withaferin A-analogues as potent apoptotic inducers
      283. Studies on oral bioavailability and first‐pass metabolism of withaferin A in rats using LC–MS/MS and Q‐TRAP
      284. Study on the Anticarcinogenic Efficacy of Withaferin-A in DEN Induced Hepatocellular Carcinoma: Morphology and Histopathology
      285. Synergistic antitumor activity of withaferin A combined with oxaliplatin triggers reactive oxygen species-mediated inactivation of the PI3K/AKT pathway in human …
      286. Synergistic cytotoxic action of cisplatin and withaferin A on ovarian cancer cell lines
      287. Synergistic inhibition of glioma cell proliferation by withaferin A and tumor treating fields
      288. Synthetic studies of withanolide I Synthesis of AB ring moiety of withaferin A
      289. Targeting glioblastoma stem cells with withaferin A
      290. Targeting Her-2/neu breast cancers with a plant derived natural compound, withaferin A (53.15)
      291. Targeting NFκB and MAP Kinases in Pancreatic Beta Cells to Suppress Islet Inflammation By withaferin A.: Abstract# C1727
      292. Targeting RAW 264.7 macrophages (M1 type) with Withaferin-A decorated mannosylated liposomes induces repolarization via downregulation of NF-κB and …
      293. The Anti-Angiogenic Activity of withaferin A Is Mediated by the Intermediate Filament Protein Vimentin
      294. The chemopreventive effect of withaferin A on spontaneous and inflammation-associated colon carcinogenesis models
      295. The effect of withaferin A on human peripheral blood lymphocytes: An electron-microscope study
      296. The effect of withaferin A on plant cells
      297. The effect of withaferin A, a natural steroidal lactone, on the fine structure of S-180 tumor cells
      298. The Effects of withaferin A on Normal and Malignant Immune Cells
      299. The glucose metabolism targeting therapies and withaferin A eliminate epidermal growth factor tyrosine kinase inhibitor-induced drug-tolerant persisters in non-small …
      300. The inhibitory effect of withaferin A on the growth of orthotopic xenograft tumor of hepatocellular carcinoma in nude mice and the mechanism
      301. The Natural Compound withaferin A Covalently Binds to Cys239 of β-Tubulin to Promote Tubulin Degradation
      302. The tumor inhibitor and antiangiogenic agent withaferin A targets the intermediate filament protein vimentin
      303. The tumor proteasome is a primary target for the natural anticancer compound withaferin A isolated from “Indian winter cherry”
      304. The use of withaferin A to study intermediate filaments
      305. Therapeutic relevance of withaferin-A induced apoptotic and autophagic regulation in human cancer cell-lines
      306. Thiol dependent NF-κB suppression and inhibition of T-cell mediated adaptive immune responses by a naturally occurring steroidal lactone withaferin A
      307. To check the glioprotective effect of withaferin A on C6 Glioma cell Culture challenged with Kainic Acid
      308. To Test The Role Of withaferin A In Neuroprotection On Sh-Sy5Y Cell Line Challenged By Kainic Acid
      309. Towards Therapeutic Chemical Genetics: Polypharmacology of withaferin A on Corneal Angiogenesis and Retinal Gliosis is Mediated by Type III Intermediate …
      310. Treatment of adult and pediatric high-grade gliomas with withaferin A: antitumor mechanisms and future perspectives
      311. Tumor inhibitors. XXXIX. Active principles of Acnistur arborescens. Isolation and structural and spectral studies of withaferin A and withacnistin
      312. Tumor Size Reduction With withaferin A In A Murine Model Of Uveal Melanoma
      313. Validated HPLC method development for simultaneous analysis of withaferin-A and 6-gingerol
      314. Vassobia breviflora root-extract withaferin A as a novel cytotoxic and synergistic agent against malignant gliomas
      315. Vimentin and Glial Fibrillar Acidic Protein are Targeted by withaferin A in Retinal Gliosis
      316. Vimentin Phosphorylation Underlies Corneal Myofibroblast Sensitivity to withaferin A
      317. Vimentin phosphorylation underlies myofibroblast sensitivity to withaferin A in vitro and during corneal fibrosis
      318. Water-soluble withaferin A polymer prodrugs via a drug-functionalized RAFT CTA approach
      319. withaferin A
      320. withaferin A (WFA) inhibits tumor growth and metastasis by targeting ovarian cancer stem cells
      321. withaferin A abolishes the stem cell factor-stimulated pigmentation of human epidermal equivalents by interrupting the auto-phosphorylation of c-KIT in human …
      322. withaferin A activates stress signalling proteins in high risk acute lymphoblastic leukemia
      323. withaferin A activity against glioblastoma cells: Supression of microtubule dynamics
      324. withaferin A alone and in combination with cisplatin suppresses growth and metastasis of ovarian cancer by targeting putative cancer stem cells
      325. withaferin A alters intermediate filament organization, cell shape and behavior
      326. withaferin A ameliorates ovarian cancer-induced cachexia and proinflammatory signaling
      327. withaferin A ameliorates renal injury due to its potent effect on inflammatory signaling
      328. withaferin A analogs that target the AAA+ chaperone p97
      329. withaferin A analogues up-regulate the MAPK and glutathione metabolic pathways prior to activation of apoptosis in pancreatic cancer cells
      330. withaferin A and its potential role in glioblastoma (GBM)
      331. withaferin A and sulforaphane regulate breast cancer cell cycle progression through epigenetic mechanisms
      332. withaferin A and tumor treating fields synergistically inhibit glioma proliferation
      333. withaferin A and Withanolide D analogues with dual heat-shock-inducing and cytotoxic activities: semisynthesis and biological evaluation
      334. withaferin A associated differential regulation of inflammatory cytokines
      335. withaferin A attenuates Alcohol Abstinence Signs in Rats
      336. withaferin A attenuates bleomycin‐induced scleroderma by targeting FoxO3a and NF‐κβ signaling: Connecting fibrosis and inflammation
      337. withaferin A attenuates lipopolysaccharide-induced acute lung injury in neonatal rats.
      338. withaferin A Attenuates Myocardial Ischemia/Reperfusion Injury via Mitochondrial Death Cascade Blockade in an AMPK Dependent Manner
      339. withaferin A attenuates ovalbumin induced airway inflammation
      340. withaferin A binds covalently to the N-terminal domain of annexin A2
      341. withaferin A blocks formation of IFN-γ-induced metastatic cancer stem cells through inhibition of the CXCR4/CXCL12 pathway in the UP-LN1 carcinoma cell model
      342. withaferin A causes activation of Notch2 and Notch4 in human breast cancer cells
      343. withaferin A causes autophagy in normal as well as cancerous human breast cells
      344. withaferin A causes FOXO3a-and Bim-dependent apoptosis and inhibits growth of human breast cancer cells in vivo
      345. withaferin A disrupts ubiquitin-based NEMO reorganization induced by canonical NF-κB signaling
      346. withaferin A down-regulates lipopolysaccharide-induced cyclooxygenase-2 expression and PGE2 production through the inhibition of STAT1/3 activation in microglial …
      347. withaferin A downregulates tubulins and covalently binds β-tubulin at cysteine-303 in human breast cancer cells
      348. withaferin A effectively targets soluble vimentin in the glaucoma filtration surgical model of fibrosis
      349. withaferin A enhances radiation-induced apoptosis in Caki cells through induction of reactive oxygen species, Bcl-2 downregulation and Akt inhibition
      350. withaferin A exerts anti-tumor effects in gliobIastoma cells by arresting cell cycle at G2/M phase
      351. withaferin A from cell cultures of Withania somnifera
      352. withaferin A Improves Nonalcoholic Steatohepatitis in Mice
      353. withaferin A in combination with cisplatin targets CD44 and Oct4 positive cancer stem cells in ovarian cancer
      354. withaferin A induced impaired autophagy and unfolded protein response in human breast cancer cell-lines MCF-7 and MDA-MB-231
      355. withaferin A induces apoptosis and inhibits adipogenesis in 3T3‐L1 adipocytes
      356. withaferin A induces apoptosis by activating p38 mitogen-activated protein kinase signaling cascade in leukemic cells of lymphoid and myeloid origin through …
      357. withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cells
      358. withaferin A induces apoptosis in human melanoma cells through generation of reactive oxygen species and down-regulation of Bcl-2
      359. withaferin A induces apoptosis in rat C6 glioma cells through regulating NF-ΚB nuclear translocation and activation of caspase cascade
      360. withaferin A induces apoptosis through the generation of thiol oxidation in human head and neck cancer cells
      361. withaferin A induces cell death and differentiation in multiple myeloma cancer stem cells
      362. withaferin A induces cell death selectively in androgen-independent prostate cancer cells but not in normal fibroblast cells
      363. withaferin A induces cytoprotective autophagy in hepatocellular cancer cells and concomitant autophagic inhibition augments the efficacy of withaferin A in …
      364. withaferin A induces heme oxygenase (HO-1) expression in endothelial cells via activation of the Keap1/Nrf2 pathway
      365. withaferin A induces mitochondrial-dependent apoptosis in non-small cell lung cancer cells via generation of reactive oxygen species.
      366. withaferin A induces nonprotective autophagy in a STK11-independent manner and mediates breast cancer inhibition via energetic impairment
      367. withaferin A induces Nrf2-dependent protection against liver injury: role of Keap1-independent mechanisms
      368. withaferin A induces oxidative stress-mediated apoptosis and DNA damage in oral cancer cells
      369. withaferin A Induces p27Kip1 Expression to Inhibit Corneal Angio-Fibrosis
      370. withaferin A induces p53-dependent apoptosis by repression of HPV oncogenes and upregulation of tumor suppressor proteins in human cervical cancer cells
      371. withaferin A induces proteasome inhibition, endoplasmic reticulum stress, the heat shock response and acquisition of thermotolerance
      372. withaferin A induces proteasome-dependent degradation of breast cancer susceptibility gene 1 and heat shock factor 1 proteins in breast cancer cells
      373. withaferin A induces ROS-mediated paraptosis in human breast cancer cell-lines MCF-7 and MDA-MB-231
      374. withaferin A inhibits activation of signal transducer and activator of transcription 3 in human breast cancer cells
      375. withaferin A inhibits adipogenesis in 3T3-F442A cell line, improves insulin sensitivity and promotes weight loss in high fat diet-induced obese mice
      376. withaferin A inhibits apoptosis via activated Akt-mediated inhibition of oxidative stress
      377. withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
      378. withaferin A inhibits epithelial to mesenchymal transition in non-small cell lung cancer cells
      379. withaferin A inhibits epithelial-to-mesenchymal transition in non-small lung cell cancer cells via regulation of SMAD and NFkB signaling
      380. withaferin A inhibits experimental epithelial–mesenchymal transition in MCF‐10A cells and suppresses vimentin protein level in vivo in breast tumors
      381. withaferin A inhibits expression of ataxia telangiectasia and Rad3‐related kinase and enhances sensitivity of human breast cancer cells to cisplatin
      382. withaferin A inhibits helicobacter pylori-induced production of IL-1β in dendritic cells by regulating NF-κB and NLRP3 inflammasome activation
      383. withaferin A inhibits hepatoma cell proliferation through induction of apoptosis and cell cycle arrest
      384. withaferin A inhibits in vivo growth of breast cancer cells accelerated by Notch2 knockdown
      385. withaferin A inhibits inflammatory responses induced by Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans in macrophages
      386. withaferin A inhibits iNOS expression and nitric oxide production by Akt inactivation and down-regulating LPS-induced activity of NF-κB in RAW 264.7 cells
      387. withaferin A inhibits JAK/STAT3 signaling and induces apoptosis of human renal carcinoma Caki cells
      388. withaferin A inhibits lysosomal activity to block autophagic flux and induces apoptosis via energetic impairment in breast cancer cells
      389. withaferin A inhibits matrix metalloproteinase-9 activity by suppressing the Akt signaling pathway
      390. withaferin A inhibits NF-kappaB activation by targeting cysteine 179 in IKKβ
      391. withaferin A inhibits nuclear factor-κB-dependent pro-inflammatory and stress response pathways in the astrocytes
      392. withaferin A inhibits osteosarcoma cells through inactivation of Notch-1 signalling
      393. withaferin A inhibits pro-inflammatory cytokine-induced damage to islets in culture and following transplantation
      394. withaferin A inhibits prostate carcinogenesis in a PTEN-deficient mouse model of prostate cancer
      395. withaferin A inhibits STAT3 and induces tumor cell death in neuroblastoma and multiple myeloma
      396. withaferin A inhibits the malignant pleural mesothelioma growth in vitro and in vivo
      397. withaferin A inhibits the proliferation of gastric cancer cells by inducing G2/M cell cycle arrest and apoptosis
      398. withaferin A inhibits the proteasome activity in mesothelioma in vitro and in vivo
      399. withaferin A inhibits tumor necrosis factor-α-induced expression of cell adhesion molecules by inactivation of Akt and NF-κB in human pulmonary epithelial cells
      400. withaferin A Is a Chemical Genetic Probe of the Intermediate Filament Protein Vimentin
      401. withaferin A is a leptin sensitizer with strong antidiabetic properties in mice
      402. withaferin A is a potent inhibitor of angiogenesis
      403. withaferin A is an inhibitor of endothelial protein C receptor shedding in vitro and in vivo
      404. withaferin A is effective in inhibiting the survival of B cell lymphomas and chronic lymphocytic leukemias (P2052)
      405. withaferin A modulates AIM2 inflammasome and caspase-1 expression in THP-1 polarized macrophages
      406. withaferin A modulates the Spindle Assembly Checkpoint by degradation of Mad2–Cdc20 complex in colorectal cancer cell lines
      407. withaferin A Prevents Myocardial Ischemia/Reperfusion Injury by Upregulating AMP-Activated Protein Kinase-Dependent B-Cell Lymphoma2 Signaling
      408. withaferin A Production by Root Cultures of Withania coagulans
      409. withaferin A promotes proliferation and migration of brain endothelial cells
      410. withaferin A Protects Against High-Fat Diet–Induced Obesity Via Attenuation of Oxidative Stress, Inflammation, and Insulin Resistance
      411. withaferin A protects against palmitic acid-induced endothelial insulin resistance and dysfunction through suppression of oxidative stress and inflammation
      412. withaferin A protects against spinal cord injury by inhibiting apoptosis and inflammation in mice
      413. withaferin A regulates LRRK2 levels by interfering with the Hsp90-Cdc37 chaperone complex
      414. withaferin A Regulates Muller Glial Cell Cycle During Retinal Gliosis
      415. withaferin A reverses bile duct ligation‐induced liver fibrosis by modulating extracellular matrix deposition: Role of LOXL2/Snail1, vimentin, and NFκB signaling
      416. withaferin A sensitizes TRAIL-induced apoptosis through reactive oxygen species-mediated up-regulation of death receptor 5 and down-regulation of c-FLIP
      417. withaferin A strongly elicits IκB kinase β hyperphosphorylation concomitant with potent inhibition of its kinase activity
      418. withaferin A suppresses and inhibits hepatocellular carcinoma-cell proliferation and tumor burden via activation of ERK1/2-ELK1-RSK-DR5 axis
      419. withaferin A suppresses anti-apoptotic BCL2, Bcl-xL, XIAP and Survivin genes in cervical carcinoma cells
      420. withaferin A suppresses Beta amyloid in APP expressing cells: Studies for Tat and Cocaine associated neurological dysfunctions
      421. withaferin A suppresses estrogen receptor‐α expression in human breast cancer cells
      422. withaferin A suppresses liver tumor growth in a nude mouse model by downregulation of cell signaling pathway leading to invasion and angiogenesis
      423. withaferin A suppresses the expression of vascular endothelial growth factor in Ehrlich ascites tumor cells via Sp1 transcription factor
      424. withaferin A suppresses the growth of myelodysplasia and leukemia cell lines by inhibiting cell cycle progression
      425. withaferin A suppresses the up‐regulation of acetyl‐coA carboxylase 1 and skin tumor formation in a skin carcinogenesis mouse model
      426. withaferin A suppresses tumor promoter 12‐O‐tetradecanoylphorbol 13‐acetate‐induced decreases in isocitrate dehydrogenase 1 activity and mitochondrial function …
      427. withaferin A synergistically enhances the effects of paclitaxel against lung cancer.
      428. withaferin A synergizes the therapeutic effect of doxorubicin through ROS-mediated autophagy in ovarian cancer
      429. withaferin A targeting both cancer stem cells and metastatic cancer stem cells in the UP-LN1 carcinoma cell model
      430. withaferin A targets apoptosis inhibitor cIAP1: A potential anticancer candidate
      431. withaferin A targets heat shock protein 90 in pancreatic cancer cells
      432. withaferin A targets intermediate filaments glial fibrillary acidic protein and vimentin in a model of retinal gliosis
      433. withaferin A triggers G2/M arrest and intrinsic apoptosis in glioblastoma cells via ATF4‐ATF3‐CHOP axis
      434. withaferin A, a constituent of Indian Ayurvedic medicinal plant Withania somnifera, causes G2 phase and mitotic arrest in human breast cancer cells
      435. withaferin A, a Cytotoxic Steroid from Vassobia breviflora, Induces Apoptosis in Human Head and Neck Squamous Cell Carcinoma
      436. withaferin A, a natural compound with anti-tumor activity, is a potent inhibitor of transcription factor C/EBPβ
      437. withaferin A, a novel compound of Indian ginseng (Withania somnifera), ameliorates Cerulein‐induced acute pancreatitis: Possible role of oxidative stress and …
      438. withaferin A, a potent and abundant component of Withania somnifera root extract, reduces myeloid-derived suppressor cell function (P2103)
      439. withaferin A, a potent and abundant component of Withania somnifera root extract, reduces myeloid-derived suppressor cell function.
      440. withaferin A, a Potential Regulator of Astrocyte Reactivity
      441. withaferin A, a Steroidal Lactone from Withania somnifera, Induces Mitotic Catastrophe and Growth Arrest in Prostate Cancer Cells
      442. withaferin A: a new radiosensitizer from the Indian medicinal plant Withania somnifera
      443. withaferin A: A NOVEL THERAPEUTIC APPROACH FOR MALIGANT BRAIN TUMORS
      444. withaferin A: a proteasomal inhibitor promotes healing after injury and exerts anabolic effect on osteoporotic bone
      445. withaferin A: From ayurvedic folk medicine to preclinical anti-cancer drug
      446. withaferin A–A Phytosteroid of Promise for Tumour Sensitization in Cancer Therapy
      447. withaferin A-caused production of intracellular reactive oxygen species modulates apoptosis via PI3K/Akt and JNKinase in rabbit articular chondrocytes
      448. withaferin A-induced apoptosis in human breast cancer cells is associated with suppression of inhibitor of apoptosis family protein expression
      449. withaferin A-induced apoptosis in human breast cancer cells is mediated by reactive oxygen species
      450. withaferin A-mediated apoptosis in breast cancer cells is associated with alterations in mitochondrial dynamics
      451. withaferin A-mediated inhibition of breast carcinoma involves concomitant activation of CHOP and Elk1 via ERK/ribosomal S6 kinase (RSK) signaling axis regulating …
      452. withaferin A-related steroids from Withania aristata exhibit potent antiproliferative activity by inducing apoptosis in human tumor cells
      453. withaferin A-stimulated Ca2+ entry, ceramide formation and suicidal death of erythrocytes
      454. Withaferin-A as a Potential Candidate for Cancer Therapy: Experimental Evidence of Its Effects on Telomerase Plus and Minus Cancer Cells
      455. Withaferin-A attenuates multiple low doses of Streptozotocin (MLD-STZ) induced type 1 diabetes
      456. Withaferin-A displays enhanced anxiolytic efficacy without tolerance in rats following sub chronic administration
      457. Withaferin-A in Ameliorating the Effects of High Glucose on Inflammatory and Phagocytic Response of Mouse Macrophages.
      458. Withaferin-A induces apoptosis in osteosarcoma U2OS cell line via generation of ROS and disruption of mitochondrial membrane potential
      459. Withaferin-A inhibits colon cancer cell growth by blocking STAT3 transcriptional activity
      460. Withaferin-A Inhibits Growth of Drug-Resistant Breast Carcinoma by Inducing Apoptosis and Autophagy, Endogenous Reactive Oxygen Species (ROS) …
      461. Withaferin-A inhibits prostate tumor growth by enhancing anti-tumor immune response
      462. Withaferin-A isolated from the cell cultures of Withania somnifera
      463. Withaferin-A isolated from the cell cultures of Withania somnifera.
      464. Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences
      465. Withaferin-A reduces acetaminophen-induced liver injury in mice
      466. Withaferin-A reduces type I collagen expression in vitro and inhibits development of myocardial fibrosis in vivo
      467. Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells
      468. Withaferin-A, a steroidal lactone encapsulated mannose decorated liposomes ameliorates rheumatoid arthritis by intriguing the macrophage repolarization in adjuvant …
      469. Withaferin-A: A Potential Anticancer Withanolide from Withania somnifera (L.) Dun.
      470. Withaferin-A—A natural anticancer agent with pleitropic mechanisms of action
      471. Withania somnifera (Ashwagandha) and withaferin A: Potential in integrative oncology
      472. Withania somnifera chemotypes NMITLI 101R, NMITLI 118R, NMITLI 128R and withaferin A protect Mastomys coucha from Brugia malayi infection
      473. Withania somnifera Extract/withaferin A as a Prospective Anti-pigmenting Agent
      474. WITHDRAWN: Anti-tumor and proapoptotic effect of withaferin A is mediated by up-regulation of Bax and inhibition NF-κB in Ehrlich ascites tumor cells
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