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    • ABOUT
    • SCIENTIFIC STUDIES
      • ADAPTOGENS
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    0
    ALZHEIMER’S, DEMENTIA, PARKINSON’S
    February 2, 2020
    FOXO4
    February 10, 2020
    1. 1, 25-Dihydroxyvitamin D3 Treatment Delays Cellular Aging In Human Mesenchymal Stem Cells While Maintaining Their Multipotent Capacity
    2. 14Th Napreca Symposium And Aamps Ethnoveterinary Medicine…
    3. 1-Deoxynojirimycin Attenuates High Glucose-Accelerated Senescence In Human Umbilical Vein Endothelial Cells
    4. 24: Cerebral White Matter Lesions In Formerly (Pre)-Eclamptic Women
    5. A Deficit In Collagenase Activity Contributes To Impaired Migration Of Aged Microvascular Endothelial Cells
    6. A Drug-Induced Accelerated Senescence (Dias) Is A Possibility To Study Aging In Time Lapse
    7. A Functional Study Of Adamts7 Gene Variants.
    8. A G2/M Growth Arrest Response To Low-Dose Intermittent H2O2 In Normal Uroepithelial Cells.
    9. A Genetic Screening Identifies A Component Of The Swi/Snf Complex, Arid1B As A Senescence Regulator
    10. A Method For Fluorescent Hplc Analysis Of Cs/Ds Glycosaminoglycans
    11. A New 4-(Pyridinyl)-4H-Benzo[G]Chromene-5,10-Dione Ruthenium(Ii) Complex Inducing Senescence In 518A2 Melanoma Cells
    12. A Novel Keratanase‐Generated Keratan Sulfate Antibody And Its Application To Structural Analysis Of Skeletal And Corneal Keratan Sulfate
    13. A P53-Dependent Response Limits Epidermal Stem Cell Functionality And Organismal Size In Mice With Short Telomeres
    14. A Possible Role Of Stress-Induced Premature Senescence , Sips, As A Producer Of The Stress-Resistant Microenvironment
    15. A Study Of Cell Death Pathways And Innate Immunity In Cancer Chemotherapy
    16. A Synthetic Formulation, Dhanwantharam Kashaya, Delays Senescence In Stem Cells
    17. A Triad Of Nrp2, Dlx And P53 Proteins In Lung Cancer Metastasis
    18. Absence Of Replicative Senescence In Cultured Cells From The Short-Lived Killifish Nothobranchius Furzeri
    19. Abstract B175: Rational Combination Of Mtor And Aurora Kinase A Inhibition In Preclinical Models Of Triple-Negative Breast Cancer
    20. Abstract B63: Differences Between Replicative Senescence -Versus Radiation-Associated Secretory Phenotype
    21. Abstract Lb-32: Glioma Treatment With Temozolomide And Notch Inhibition Suppresses Neurosphere Formation And Xenograft Formation
    22. Abstract# 2194: Otx2 In Medulloblastoma: Its Function And Targets
    23. Accelerated Senescence Of Cord Blood Endothelial Progenitor Cells From Premature Neonates Is Driven By Sirt1 Decreased Expression
    24. Accelerated Tubular Cell Senescence In Smp30 Knockout Mice
    25. Activation Of A Camp Pathway And Induction Of Melanogenesis Correlate With Association Of P16Ink4 And P27Kip1 To Cdks, Loss Of E2F-Binding Activity, And …
    26. Acute Activation Of Amp-Activated Protein Kinase Prevents H2O2-Induced Premature Senescence In Primary Human Keratinocytes
    27. Acute Effects Of Rb In Retinoblastoma Cells
    28. Acyl-Coenzyme A Synthetase 5 Levels In Urothelial Cellines And Bladder Cancer Tissues Reflect Cellular Differentiation And Senescence .
    29. Adamts‐4 Activity On A Proteoglycan Vs. A Polypeptide Is Controlled By The Ancillary Domains
    30. Adenoviral P16/Cdkn2 Gene Transfer To Malignant Glioma: Role Of P16 In Growth, Invasion, And Senescence
    31. Administration Of L-Arginine Plus L-Citrulline Or L-Citrulline Alone Successfully Retarded Endothelial Senescence
    32. Ageing Of Neural Stem Cells In A Parkinson’S Disease Model
    33. Age-Like Phenotype Of Microglia During Hiv-1 Infection
    34. Age‐Related Changes In Human Meniscal Glycosaminoglycans
    35. Aging Alters The Molecular Dynamics Of Synapses In A Sexually Dimorphic Pattern In Zebrafish (Danio Rerio)
    36. Aging Decreases Collagen Iv Expression In Vivo In The Dermo-Epidermal Junction And In Vitro In Dermal Fibroblasts: Possible Involvement Of Tgf-Β1
    37. Alain Meybeck
    38. Alpha-Ketoglutarate, An Endogenous Metabolite, Extends Lifespan And Compresses Morbidity In Aging Mice
    39. Altered Signal Transduction Pathways In Melanoma
    40. Alternative Splicing Targeting The Htaf4-Tafh Domain Of Taf4 Represses Proliferation And Accelerates Chondrogenic Differentiation Of Human Mesenchymal …
    41. An Interaction Between Opticin And Heparan Sulfate May Provide The Molecular Basis For Vitreoretinal Adhesion
    42. An Ultrastructural Investigation Of Dermatopontin‐Knockout Mouse Corneas
    43. Analysis Of Cd44 Hyaluronan‐Binding Domain Mutants By Nmr
    44. Analytical Strategies For Identifying Relevant Phenotypes In Microarray Data
    45. Angiostatic Mechanisms Of Endogenous Angiogenesis Inhibitors
    46. Angiotensin Ii Induces Endothelial Cell Senescence Via The Activation Of Mitogen‐Activated Protein Kinases
    47. Annals Of Biotechnology
    48. Annulus Cells From More Degenerated Human Discs Show Modified Gene Expression In 3D Culture Compared With Expression In Cells From Healthier Discs
    49. Anti-Aging Effects Of The Proteins From Artemia Extract On Human Fibroblasts Cell Proliferation And Collagen Expression In Induced Aging Conditions
    50. Anti-Cd20 Immunotherapy Augments The Chemotherapy-Induced Senescence Response In Human Lymphoma Cells
    51. Anti‐Inflammatory Actions Of Green Tea Catechins And Ligands Of Peroxisome Proliferator‐Activated Receptors
    52. Anti-Photoaging Potential Of Botulinum Toxin Type A In Uvb-Induced Premature Senescence Of Human Dermal Fibroblasts In Vitro Through Decreasing Senescence …
    53. Approach Of Evolutionary Theories Of Ageing, Stress, Senescence -Like Phenotypes, Calorie Restriction And Hormesis From The View Point Of Far-From-Equilibrium …
    54. Areca Nut Extract Induced Senescence In Human Oral Fibroblasts Enhances Tumorigenesis Of Oral Cancer Cells
    55. Argyrin F Therapy Attenuates Carcinogensis Of Pancreatic Adenocarcinoma (Pdac)
    56. Attenuated Expression Of 70-Kda Heat Shock Protein In Wi-38 Human Fibroblasts During Aging In Vitro
    57. Author’S Response To Commentary: Cell Senescence : An Evaluation Of Replicative Senescence In Culture As A Model For Aging In Situ
    58. B60 Smoking And Particulates Impact On Lung Health: Cigarette Smoke Induces Human Airway Epithelial Senescence Via Growth Differentiation Factor …
    59. Basic—Liver, Pancreas, And Biliary Tract
    60. Beware Of Your Cre‐Ation: Lacz Expression Impairs Neuronal Integrity And Hippocampus‐Dependent Memory
    61. Biogenesis Of Pro-Senescent Microparticles By Endothelial Colony Forming Cells From Premature Neonates Is Driven By Sirt1-Dependent Epigenetic Regulation …
    62. Biological Effects Of Cigarette Smoke In Cultured Human Retinal Pigment Epithelial Cells
    63. Biological Impact Of Senescence Induction In Prostate Cancer Therapy
    64. Biological Significance Of Dna Damage Checkpoint And The Mode Of Checkpoint Signal Amplification
    65. Biosynthesis Of Heparan Sulfate–How Regulated Does It Need To Be?
    66. Blockade Of Stat3 Oncogene Addiction Induces Cellular Senescence And Reveals A Cell-Nonautonomous Activity Suitable For Cancer Immunotherapy
    67. Bmi1 Polycomb Group Protein Acts As A Master Switch For Growth And Death Of Tumor Cells: Regulates Tcf4-Transcriptional Factor-Induced Bcl2 Signaling
    68. Bmp7 Induces Dormancy Of Prostatic Tumor Stem Cell In Bone
    69. Bone Marrow-Derived Mesenchymal Stem Cells In Three-Dimensional Co-Culture Attenuate Degeneration Of Nucleus Pulposus Cells
    70. Book Of Extended Abstracts (Pdf)-9.1 Mb-Napreca
    71. Bozepinib, A Novel Small Antitumor Agent, Induces Pkr-Mediated Apoptosis And Synergizes With Ifnα Triggering Apoptosis, Autophagy And Senescence
    72. Bypassing Cellular Senescence By Genetic Screening Tools
    73. C67 Acute Lung Injury: Mitochondrial Oxphos (Complex Iii) Is An Important Regulator Of Fibroblast Differentiation: Implications In Bioenergetics And Cellular …
    74. Cancer Driver Mutations In Endometriosis: Variations On The Major Theme Of Fibrogenesis
    75. Cancer Vaccines And Immunotherapeutic Approaches In Hepatobiliary And Pancreatic Cancers
    76. Carbohydrate Microarrays And The Unravelling Of Ligands For Effector Proteins Of The Immune System
    77. Caveolin-1 Mediated P53 Activation In Stress Induced Premature Senescence And Its Antagonistic Pleiotropic Implications In Cancer
    78. Cd276 (B7‐H3) Maintains Proliferation And Regulates Differentiation In Angiogenic Function In Late Endothelial Progenitor Cells
    79. Cdh1 Regulates Cell Cycle Through Modulating The Claspin/Chk1 And The Rb/E2F1 Pathways
    80. Cdk4/6 And Autophagy Inhibitors Synergistically Induce Senescence In Rb Positive Cytoplasmic Cyclin E Negative Cancers
    81. Cell Cultures From Walleye (Sander Vitreus) For Use In Cell Biology And Virology
    82. Cellular Aging In Cardiovascular Diseases
    83. Senescence -assay_0.pdf” target=”_blank” rel=”noopener” data-saferedirecturl=”https://www.google.com/url?hl=en&q=http://www.meditecno.pt/Upload/Product/Archive/CBA-230-cellular-Senescence -assay_0.pdf&source=gmail&ust=1581475763360000&usg=AFQjCNESAjiHWM2ymArQTBQ87LFaDkqx0A”>Cellular Senescence Assay Kit (SA-β-ga l Staining)
    84. Cellular Senescence Mechanisms Independent Of Telomere Shortening And Telomerase: Other Barriers To Cell Immortalization And Carcinogenesis
    85. Changes In Mitochondrial Fitness Of Fibroblasts Due To Oxidative Stress
    86. Changes In Mucin‐Type O‐Glycosylation In Breast Cancer: Implications For The Host Immune Response
    87. Characterisation And Manipulation Of Docetaxel Resistant Prostate Cancer Cell Lines
    88. Characteristics Of Mitotic Cell Death Induced By Enediyne Antibiotic Lidamycin In Human Epithelial Tumor Cells
    89. Characterization Of A Murine Hypomorphic Allele Of The Spindle Checkpoint Gene Bub1 And Its Role In Tumorigenesis
    90. Characterization Of Bone Marrow Stromal Clonal Populations Derived From Osteoarthritis Patients
    91. Characterization Of The Thioredoxin System In The Diabetic Retina
    92. Characterizing The Role Of Non Muscle Myosin Ii In Proliferation And The Effect Of Serum Deprivation On Maintenance Of Pluripotency Of Human Wharton’S Jelly …
    93. Characterizing The Role Of The Chromatin Remodeling Component Arid1A As A Suppressor Of Sporadic Mammary Tumors In Mice
    94. Characterizing The Role Of The Retinoblastoma Protein Lxcxe Binding Cleft In Cellular Senescence And Tumor Suppression
    95. Chronic Diarrhea And Weight Loss Due To Vibrio Parahaemolyticus Infection In A Renal Transplant Recipient
    96. Chronic In Vitro Exposure To 3′-Azido-2′, 3′-Dideoxythymidine Induces Senescence And Apoptosis And Reduces Tumorigenicity Of Metastatic Mouse Mammary Tumor …
    97. Ciliary Abnormalities In Senescent Human Fibroblasts Impair Proliferative Capacity
    98. Circular Rna Expression Profile In Human Fibroblast Premature Senescence After Repeated Ultraviolet B Irradiations Revealed By Microarray
    99. Cisplatin-Induced P53-Independent Growth Arrest And Cell Death In Cancer Cells.
    100. Cited2, A Novel Egfr-Induced Coactivator, Plays A Key Role In Lung Cancer Progression
    101. Claudio M. Aldaz, Md, Ph. D.
    102. Cold Atmospheric Plasma Causes A Calcium Influx In Melanoma Cells Triggering Cap-Induced Senescence
    103. Cold Atmospheric Plasma, A New Strategy To Induce Senescence In Melanoma Cells
    104. Collagenase‐Resistant Collagen Promotes Mouse Aging And Vascular Cell Senescence
    105. Combinatorial Effects Of Continuous Protein Synthesis, Erk-Signaling, And Reactive Oxygen Species On Induction Of Cellular Senescence
    106. Common Genes Responsible For Differentiation And Senescence Of Human Mucosal And Epidermal Keratinocytes
    107. Comparative Proteome Analysis Of Splenic Lymphocytes In Senescence -Accelerated Mice
    108. Comparison Of Early Passage, Senescent And Htert Immortalized Endothelial Cells
    109. Comparison Of Fibronectin And Collagen In Supporting The Isolation And Expansion Of Endothelial Progenitor Cells From Human Adult Peripheral Blood
    110. Comparison Of Proliferation, Senescence And Differentiation Into Skeletal Cell Lineages Of Murine Bone Marrow-Derived And Amniotic Fluid Mesenchymal Stem Cells
    111. Conformation Of Glycosaminoglycans By Ion Mobility Mass Spectrometry
    112. Conformations Of Cell Surface Oligosaccharides And Recognition By Lectins From Pathogens
    113. Contribution Of Estrogen Receptor-Α And Progesterone Receptor-B To Oncogenic K-Ras-Mediated Nih3T3 Cell Transformation
    114. Contributions Of Pten To Pml-Iv-Mediated Cellular Senescence And Free Fatty Acid-Induced Oxidative Stress
    115. Cyclin E Associates With Baf155 And
    116. Cystathionine beta Synthase Modulates Senescence Of Human Endothelial Cells
    117. D108 Cell Fate Decisions: Senescence , Repair, And Regeneration: Lung Fibroblasts Of Ipf Patients Display Senescence -Like Features In Vitro
    118. Deacetylation Of H4-K16Ac And Heterochromatin Assembly In Senescence
    119. Deletion Of Sphingosine Kinase 1 Inhibits Liver Tumorigenesis In Diethylnitrosamine-Treated Mice
    120. Development Of An Atlantic Salmon Heart Endothelial Cell Line (Ashe) That Responds To Lysophosphatidic Acid (Lpa)
    121. Development Of An Atlantic Salmon Heart Endothelial Cell Line (Ashe) That Responds To Lysophosphatidic Acid (Lpa) Animal
    122. Diamond Sponsor
    123. Differential Expression Of Dna Double-Strand Break Repair Proteins In Breast Cells
    124. Direct And Indirect Manipulation Of The Mek‐Erk Pathway Regulates The Formation Of A Pericellular Ha‐Dependent Matrix By Chick Articular Surface Cells Without …
    125. Dna Damage Detected With Γh2Ax In Endometrioid Adenocarcinoma Cell Lines
    126. Dna Damage, Discoordinated Gene Expression And Cellular Senescence In Osteoarthritic Chondrocytes
    127. Dna Methylation Changes In Hematopoietic Development And Ipsc-Derived Model Systems
    128. Does The Cellular Glycome Influence The Binding Properties And Signalling Functions Of Siglecs In The Immune System?
    129. Downregulation Of Histone H3 Lysine 9 Methyltransferase G9A Induces Centrosome Disruption And Chromosome Instability In Cancer Cells
    130. Drosophila Melanogaster Mitochondrial Hsp22: A Role In Resistance To Oxidative Stress, Aging And The Mitochondrial Unfolding Protein Response
    131. Dual Roles Of Erk1/2 In Cellular Senescence Induced By Excess Thymidine In Hela Cells
    132. Dynamic Regulation Of P53 Subnuclear Localization And Senescence By Morc3
    133. E2F-1 Is A Critical Modulator Of Cellular Senescence In Human Cancer
    134. Early Inflammatory Reactions In Atherosclerosis Are Induced By Proline-Rich Tyrosine Kinase/Reactive Oxygen Species–Mediated Release Of Tumor Necrosis Factor …
    135. Echinacoside Retards Cellular Senescence Of Human Fibroblastic Cells Mrc-5
    136. Echolalia In A Liver Transplant Recipient
    137. Effect Of Antisense Human Telomerase Rna Transfection On The Growth Of Human Gastric Cancer Cell Lines
    138. Effects Of A Grapevine Shoot Extract Containing Resveratrol And Resveratrol Oligomers On Intestinal Adenoma Development In Mice: In Vitro And In Vivo Studies
    139. Effects Of Low-Dose Ala-Pdt On Fibroblast Photoaging Induced By Uva Irradiation And The Underlying Mechanisms
    140. Effects Of The Antifungal Agent Ciclopirox In Hpv‐Positive Cancer Cells: Repression Of Viral E6/E7 Oncogene Expression And Induction Of Senescence And Apoptosis
    141. Efficiency Of Human Epiphyseal Chondrocytes With Differential Replication Numbers For Cellular Therapy Products
    142. Epigenetic And Pharmacological Regulation Of Gene Exprssion Involved In Senescence And Tumor Progression
    143. Epigenetic Biomarker To Determine Replicative Senescence Of Cultured Cells
    144. Epitope Mapping Of Proteins For Heparin Binding Sites
    145. Essential Role For Premature Senescence Of Myofibroblasts In Myocardial Fibrosis
    146. Establishment And Characterization Of A Human Retinal Pericyte Line: A Novel Tool For The Study Of Diabetic Retinopathy
    147. Evolution Of Melanoma Cross-Resistance To Cd8+ T Cells And Mapk Inhibition In The Course Of Brafi Treatment
    148. Evolutionarily Conserved And Nonconserved Cellular Localizations And Functions Of Human Sirt Proteins
    149. Expression Of Caveolin-1 Induces Premature Cellular Senescence In Primary Cultures Of Murine Fibroblasts: Stress-Induced Premature Senescence Upregulates The …
    150. Expression Profiles Of P53-, P16Ink4A-, And Telomere-Regulating Genes In Replicative Senescent Primary Human, Mouse, And Chicken Fibroblast Cells
    151. Extracellular Matrix Secreted By Senescent Fibroblasts Induced By Uvb Promotes Cell Proliferation In Hacat Cells Through Pi3K/Akt And Erk Signaling Pathways
    152. Extracellular Vesicles-Mediated Epithelial Cell Senescence By Fibroblasts In Ipf Pathogenesis
    153. Extracorporeal Photopheresis In Graft-Versus-Host Disease: Ultraviolet Radiation Mediates T Cell Senescence In Vivo
    154. Far Infra-Red Therapy Promotes Ischemia-Induced Angiogenesis In Diabetic Mice And Restores High Glucose-Suppressed Endothelial Progenitor Cell Functions
    155. Frequency, Angiogenic Potential, Phenotype And Molecular Signature Of Endothelial Colony-Forming Cells Isolated From …
    156. Functional Analysis Of The Histone Arginine Methyltransferase Prmt6
    157. Gadd34 Induces P21 Expression And Cellular Senescence
    158. Gefitinib Induces Premature Senescence In Non-Small Cell Lung Cancer Cells With Or Without Egfr Gene Mutation
    159. Genes Determining Taxol Sensitivity
    160. Ginsenoside Rg1 Enhances Endothelial Progenitor Cell Angiogenic Potency And Prevents Senescence In Vitro
    161. Ginsenoside Rg1 Protects Human Fibroblasts Against Psoralen-And Uva-Induced Premature Senescence Through A Telomeric Mechanism
    162. Globular Adiponectin Improves High Glucose-Suppressed Endothelial Progenitor Cell Function Through Endothelial Nitric Oxide Synthase Dependent Mechanisms
    163. Growth Inhibition Of Hela Cells Is A Conserved Feature Of High-Risk Hpv E8^ E2C Proteins And Can Also Be Achieved By An Artificial Repressor Protein
    164. Growth Kinetics And In Vitro Aging Of Mesenchymal Stem Cells Isolated From Rat Adipose Versus Bone Marrow Tissues
    165. Heme Oxygenase-1 And Interleukin-11 Are Overexpressed In Stress-Induced Premature Senescence Of Human Wi-38 Fibroblasts Induced By Tert-Butylhydroperoxide …
    166. Heparan Sulfate Is Essential For Neuron Migration And Axon Outgrowth In Caenorhabditis Elegans
    167. High Concentrations Of Nacl Induce Cell Swelling Leading To Senescence In Human Cells
    168. High Levels Of Oncomi R‐21 Contribute To The Senescence ‐Induced Growth Arrest In Normal Human Cells And Its Knock‐Down Increases The Replicative Lifespan
    169. Highly Diverse Heparan Sulfate Analogue Libraries: A Novel Resource For Bioactivity Screening Of Proteins
    170. Histone Deacetylation As A Mechanism Of Ypel3 Down-Regulation In Er-A Positive Breast Cancer Cell Lines
    171. Hiv Infection Promotes Lung Cellular Senescence
    172. Human Dermal Fibroblasts Escape From The Long-Term Phenocopy Of Senescence Induced By Psoralen Photoactivation
    173. Human Epidermis Reconstructed From Uv-B Irradiated Keratinocytes Mimics Epidermal Ageing
    174. Human Nevi Lack Distinguishing Senescence Traits
    175. Hyaluronan: A Simple Polysaccharide With Structural Plasticity And Functional Diversity
    176. Hyperactive S6K1 Mediates Oxidative Stress And Endothelial Dysfunction In Aging: Inhibition By Resveratrol
    177. Hyperforin Induces Senescence In Endothelial And Tumor Cells
    178. Hyperoxic Exposure Increases Senescence In Type Ii-Like Mouse Lung Epithelial Cells: Role Of P53 Signaling
    179. Hyperphosphatemia Induces Senescence In Human Endothelial Cells By Increasing Endothelin‐1 Production
    180. Hyperphosphatemia Promotes Senescence Of Myoblasts By Impairing Autophagy Through Ilk Overexpression, A Possible Mechanism Involved In Sarcopenia
    181. Id3 Contributes To Cerebrospinal Fluid Seeding And Poor Prognosis In Medulloblastoma
    182. Identification Of A Gene That Reverses The
    183. Identification Of Major Heparin‐Binding Proteins In Plasma Using Electrophoresis And Mass Spectrometry
    184. Identification Of Microrna-Mrna Functional Interactions In Uvb-Induced Senescence Of Human Diploid Fibroblasts
    185. Identification Of Molecular Determinants Of Cellular Senescence In Cancer And Aging
    186. Immune Surveillance Of Senescent Cells—Biological Significance In Cancer-And Non-Cancer Pathologies
    187. Impact Of Telomere Shortening On Cell Cycle Progression And Induction Of Senescence
    188. In Cellular Senescence , The Third Circle Of The Cell Life’S Network, P53 Acts Vital Role
    189. In Vivo Imaging Of Tumor Senescence With A Novel beta –galactosidase Specific Pet Tracer
    190. Increased Arf/P53 Activity In Stem Cells, Aging And Cancer
    191. Increased Cell Senescence Is Associated With Decreased Cell Proliferation In Vivo In The Degenerating Human Annulus
    192. Increased Circulating Cd31+/Annexin V+ Apoptotic Microparticles And Decreased Circulating Endothelial Progenitor Cell Levels In Hypertensive Patients With …
    193. Increased Expression Of The Huntingtin Interacting Protein-1 Gene In Cells From Hutchinson Gilford Syndrome (Progeria) Patients And Aged Donors
    194. Increased Mitochondrial-Encoded Gene Transcription In Immortal Df-1 Cells
    195. Increased Turnover Of Proteoglycan Aggregates In Tendon Vs. Cartilage
    196. Induction De La Sénescence Endothéliale Auriculaire Par L’Angiotensine Ii Et La Thrombine: Rôle Du Stress Oxydant Et Caractérisation Du Phénotype Pro-Thrombotique, Pro …
    197. Induction Of Apoptosis In Human Replicative Senescent Fibroblasts
    198. Induction Of Atrial Endothelial Senescence By Angiotensin Ii And Thrombin: Role Of Oxidative Stress And Characterization Of Pro-Thrombotic, Pro-Adhesive, Proteolytic And …
    199. Induction Of Cellular Senescence By Insulin-Like Growth Factor Binding Protein-5 Through A P53-Dependent Mechanism
    200. Induction Of Cellular Senescence In A Telomerase Negative Human Immortal Fibroblast Cell Line, Lcs-Af. 1-3, By Human Chromosome 6
    201. Induction Of Senescence -Like State And Suppression Of Telomerase Activity Through Inhibition Of Hpv E6/E7 Gene Expression In Cells Immortalized By Hpv16 Dna
    202. Induction Of Telomere Shortening And Replicative Senescence By Cryopreservation
    203. Inhibition Of Senescence And Promotion Of The Proliferation Of Chondrocytes From Articular Cartilage By Csa And Fk506 Involves Inhibition Of P38Mapk
    204. Inhibition Of Trpm7 Blocks Mrtf/Srf-Dependent Transcriptional And Tumorigenic Activity
    205. Integrative Physiology/Experimental Medicine
    206. Integrin-Linked Kinase Regulates Senescence In An Rb-Dependent Manner In Cancer Cell Lines
    207. Interleukin-8 Release By Endothelial Colony-Forming Cells Isolated From Idiopathic Pulmonary Fibrosis Patients Might Contribute To Their Pathogenicity
    208. Intratumor Injection Of Small Interfering Rna-Targeting Human Papillomavirus 18 E6 And E7 Successfully Inhibits The Growth Of Cervical Cancer
    209. Introductory Lecture
    210. Investigating The Role Of Heparin Sulfate Proteoglycans In Hereditary Multiple Exostoses (Hme) Tumourigenesis
    211. Involvement Of Notch Signalling Pathway In Senescence Of Human Dental Pulp Cells
    212. Involvement Of Spata31 Copy Number Variable Genes In Human Lifespan
    213. Lamin B Receptor (Lbr) Is Involved In The Induction Of Cellular Senescence In Human Cells
    214. Lamin B Receptor Plays A Key Role In Cellular Senescence Induced By Inhibition Of The Proteasome
    215. Large Liver Cell Dysplasia In Hepatitis B Virus X Transgenic Mouse Liver And Human Chronic Hepatitis B Virus-Infected Liver
    216. Late Breaking Abstract-Wnt/ß-Catenin Signaling Induces Cellular Senescence In Lung Alveolar Epithelial Cells
    217. Levels Of Acyl-Coenzyme A Synthetase 5 In Urothelial Cells And Corresponding Neoplasias Reflect Cellular Differentiation
    218. Live-Cell Imaging Visualizes Frequent Mitotic Skipping During Senescence -Like Growth Arrest In Mammary Carcinoma Cells Exposed To Ionizing Radiation
    219. Low Doses Of Ionizing Radiation Suppress Doxorubicin-Induced Senescence -Like Phenotypes By Activation Of Erk1/2 And Suppression Of P38 Kinase In Mcf7 Human …
    220. Low-Dose Etoposide-Treatment Induces Endoreplication And Cell Death Accompanied By Cytoskeletal Alterations In A549 Cells: Does The Response Involve …
    221. Lsc-2017-Senolytic Drugs Target Alveolar Epithelial Cell Function And Attenuate Experimental Lung Fibrosis Ex Vivo
    222. Lung Fibroblasts Of Ipf Patients Display Senescence -Like Features In Vitro
    223. Mammalian Prohibitin Proteins Respond To Mitochondrial Stress And Decrease During Cellular Senescence
    224. Manipulation Of Molecular Pathways And Senescence Hallmarks By Natural Compounds In Fibroblast Cells
    225. Map Kinases And Heat Shock–Induced Hormesis In Human Fibroblasts During Serial Passaging In Vitro
    226. Marked Heterogeneity In Growth Characteristics Of Myoblast Clonal Cultures And Myoblast Mixed Cultures Obtained From The Same Individual
    227. Mesenchymal Stem Cells And Progenitor Cells In Connective Tissue Engineering And Regenerative Medicine: Is There A Future For Transplantation?
    228. Mesenchymal Stem Cells From Murine Amniotic Fluid As A Model For Preclinical Investigation
    229. Methionine Restriction Slows Down Senescence In Human Diploid Fibroblasts
    230. Micro Rna‐622 Is A Novel Mediator Of Tumorigenicity In Melanoma By Targeting Kirsten Rat Sarcoma
    231. Microrna 217 Modulates Endothelial Cell Senescence Via Silent Information Regulator 1
    232. Microrna Mir-885-5P Targets Cdk2 And Mcm5, Activates P53 And Inhibits Proliferation And Survival
    233. Mir-23A-Depressed Autophagy Is A Participant In Puva-And Uvb-Induced Premature Senescence
    234. Mir-93-5P Suppresses Cellular Senescence By Directly Targeting Bcl-W And P21
    235. Mnk1 Expression Increases During Cellular Senescence And Modulates The Subcellular Localization Of Hnrnp A1
    236. Modification Of The Atm/Atr Directed Dna Damage Response State With Aging And Long After Hepatocyte Senescence Induction In Vivo
    237. Modulating Human Mesenchymal Stem Cells Using Poly (N-Butyl Acrylate) Networks In Vitro With Elasticity Matching Human Arteries
    238. Modulation Of Heparan Sulfate/Chemokine Interactions Using Rna Interference
    239. Molecular Characterization Of Growth Hormone-Producing Tumors In The Gc Rat Model Of Acromegaly
    240. Molecular Determinants Of Radioresponse In Prostate Cancer
    241. Molecular Principles Of Cancer Invasion And Metastasis
    242. Molecular Recognition And Modulation Of Hepatocyte Growth Factor Activity By Heparan And Dermatan Sulfates
    243. Ms Strategies For High Throughput Glycomics And Glyco‐Proteomics
    244. Mtor Inhibition Impairs Proliferation Of Hepatocytes With Dna Damage During Chronic Liver Injury Thereby Delaying Liver Tumor Development
    245. Multi-Parameter Analysis Of Biobanked Human Bone Marrow Stromal Cells Shows Little Influence Of Donor Age And Mild Comorbidities On Phenotypic And Functional …
    246. Necdin Modulates Proliferative Cell Survival Of Human Cells In Response To Radiation-Induced Genotoxic Stress
    247. Neolignans From Saururus Chinensis Inhibit Pc-3 Prostate Cancer Cell Growth Via Apoptosis And Senescence -Like Mechanisms
    248. New Approaches For Mapping The Recognition Sites In Protein–Gag Interactions: A Study Of Gag Binding By Hepatocyte Growth Factor/Scatter Factor
    249. New Insights Into The Alternating Sequences Of Heparan Sulfate
    250. New Insights On Plm Tumor Suppressor Degradation In Cancer
    251. New Origin Firing Is Inhibited By Apc/Ccdh1 Activation In S-Phase After Severe Replication Stress.
    252. Nf‐Κb As A Determinant Of Distinct Cell Death Pathways
    253. Nf-Кb As A Determinant Of Distinct Cell Death Pathways
    254. Niacin Improves Ischemia-Induced Neovascularization In Diabetic Mice By Enhancement Of Endothelial Progenitor Cell Functions Independent Of Changes In Plasma …
    255. Nicotinamide Phosphoribosyltransferase In Smooth Muscle Cells And Aortic Integrity
    256. Nicotinamide Phosphoribosyltransferase In Smooth Muscle Cells Maintains Genome Integrity, Resists Aortic Medial Degeneration, And Is Suppressed In Human Thoracic …
    257. No Increase In Senescence ‐Associated Β‐galactosidase Activity In Werner Syndrome Fibroblasts After Exposure To H2O2
    258. Noncomposite Simultaneous Liver And Intestinal Transplantation
    259. Non-Small Cell Lung Cancer Is Susceptible To Induction Of Dna Damage Responses And Inhibition Of Angiogenesis By Telomere Overhang Oligonucleotides
    260. Novel Insights Into The Role Of Aberrantly Expressed Mnx1 (Hlxb9) In Infant Acute Myeloid Leukemia
    261. Nuclear Transfer In Rabbits With Different Types Of Donor Cells
    262. Oligomeric Collagen Xviii‐Derived Endostatin Requires Cell Surface Heparan Sulfate In Order To Induce Morphological Changes In Endothelial And Epithelial Cell Lines In …
    263. On The Relationship Of Yap And Fak In Hmscs And Osteosarcoma Cells: Discrimination Of Fak Modulation By Nuclear Yap Depletion Or Yap Silencing
    264. Oncogene-Expressing Senescent Melanocytes Up-Regulate Mhc Class Ii, A Candidate Melanoma Suppressor Function
    265. Oncogene-Induced Senescence And The Role Of P53 In Brafv600E Melanoma
    266. Onset Of Heterogeneity In Culture-Expanded Bone Marrow Stromal Cells
    267. Osteoarthritis: Aging Of Matrix And Cells-Going For A Remedy
    268. Our Products
    269. P16 Controls Epithelial Cell Growth And Suppresses Carcinogenesis Through Mechanisms That Do Not Require Rb1 Function
    270. P16 Regulation Of Lung Epithelial Cell Growth, Repair After Injury And Transformation
    271. P53-Related Apoptosis Resistance And Tumor Suppression Activity In Uvb-Induced Premature Senescent Human Skin Fibroblasts
    272. Papel Dual De La Senescencia En La Tumorigénesis
    273. Partial Lipodystrophy With Severe Insulin Resistance And Adult Progeria Werner Syndrome
    274. Pašatjaunošanās Un Paātrinātas Novecošanās Attiecības Normālās Un Vēža Šūnās Pēc Dns Bojājuma
    275. Peritoneal Dialysis: A Biological Membrane With A Nonbiological Fluid
    276. Peroxisome Senescence In Human Fibroblasts
    277. Phage Display‐Derived Antibodies: New Tools To Study Heparan Sulfate Diversity
    278. Pharmaceutical Efficacy Of Human Epiphyseal Chondrocytes With Differential Replication Numbers For Cellular Therapy Products
    279. Phenotype Specific Analyses Reveal Distinct Regulatory Mechanism For Chronically Activated P53
    280. Phosphoglucose Isomerase/Autocrine Motility Factor Plays An Important Role In Maintaining Proliferation And Suppression Of Senescence In Tumor Cells.
    281. Physiology Of Homeostasis And Repair Of Skin And The Role Of Metabolic And Endrocrine Factors
    282. Polycomb Repressive Complex 1 Coordinates Enhanced Replication And Transcription In Transit Amplifying Chondrogenic Progenitors.
    283. Poster Presentations–Sunday, September 17
    284. Postinfarction Hearts Are Protected By Premature Senescent Cardiomyocytes Via Gata 4‐Dependent Ccn 1 Secretion
    285. Powerful Graft-Versus-Leukemia Effects Exerted By Hla-Haploidentical Grafts Engrafted With A Reduced-Intensity Regimen For Relapse Following Myeloablative Hla …
    286. Probucol Inhibits Jak2−Stat Pathway Activation And Protects Human Glomerular Mesangial Cells From Tert-Butyl Hydroperoxide Induced Premature Senescence
    287. Prognostic Value Of The Sleep-Time Relative Blood Pressure Decline In Normotensive Individuals: The Hygia Proyect
    288. Promyelocytic Leukemia Protein Function In Normal, Tumor And Senescent Human Cells
    289. Protection From Oxidative Stress By Enhanced Glycolysis; A Possible Mechanism Of Cellular Immortalization
    290. Protective Effects Of Fucoidan Against Uvb-Induced Aging In Human Skin Fibroblasts
    291. Protective Effects Of Nmda Receptor Antagonist, Memantine, Against Senescence Of Pc12 Cells: A Possible Role Of Nnos And Combined Effects With Donepezil
    292. Proteinsignatur Der Replikativen Und Prämaturen Seneszenz In Humanen Nicht-Kleinzelligen Bronchialkarzinom-Und Fibroblastenzelllinien
    293. Purification And Characterization Of Endocan (Endothelial Cell‐Specific Molecule‐1), A Circulating Proteoglycan Involved In Tumour Progression And Inflammatory …
    294. Pva Combined With 0.8% Alginate: A Potential 3‐Dimensional Vehicle To Deliver And Retain Cells During Autologous Repair Of Connective Tissues?
    295. Quantitative And Integrated Proteome And Microrna Analysis Of Endothelial Replicative Senescence
    296. Radiolabeled Compounds‐Oncology (Imaging) Session 2
    297. Radiotherapy-Induced Senescence And Its Effects On Responses To Treatment
    298. Radiotracers For Noninvasive Molecular Imaging Of Tumor Cell Death
    299. Recent Advances In Conditional Cell Immortalization Technology
    300. Recent Advances In Understanding The Biomolecular Basis Of Chronic Beryllium Disease: A Review
    301. Reduced Mitochondrial Membrane Potential And Altered Responsiveness Of A Mitochondrial Membrane Megachannel In P53-Induced Senescence
    302. Regulation Of Erk1/2 Signaling In Melanoma
    303. Regulation Of Htert Expression And Function In Newly Immortalized P53 (+) Human Mammary Epithelial Cell Lines
    304. Regulation Of Promyelocytic Leukemia Protein Expression
    305. Regulation Of Signal Transduction By Glycosylation
    306. Regulation Of The Unfolded Protein Response Through Atf4 And Fam129A In Prostate Cancer
    307. Repeated Lipopolysaccharide Stimulation Induces Cellular Senescence In Bv2 Cells
    308. Replicative Senescence And Oxidant‐Induced Premature Senescence : Beyond The Control Of Cell Cycle Checkpoints
    309. Replicative Senescence Of Activated Human Hepatic Stellate Cells Is Accompanied By A Pronounced Inflammatory But Less Fibrogenic Phenotype
    310. Report Date: September 1999
    311. Restoring Effects Of Natural Anti-Oxidant Quercetin On Cellular Senescent Human Dermal Fibroblasts
    312. Restriction Of Protein Synthesis Abolishes Senescence Features At Cellular And Organismal Levels
    313. Retinoic Acid Extends The In Vitro Life Span Of Normal Human Oral Keratinocytes By Decreasing P16Ink4A Expression And Maintaining Telomerase Activity
    314. Role Of 5-Azacytidine In Therapy Of Myelodysplastic Syndrome
    315. Role Of Endonuclease G In Senescence -Associated Cell Death Of Human Endothelial Cells
    316. Role Of Heparan Sulfate In Embryoid Body Formation
    317. Role Of Melanoma Inhibitory Activity In Melanocyte Senescence
    318. Role Of Subcytotoxic Stress In Tissue Ageing
    319. Role Of The Transcription Factor T (Brachyury) In The Pathogenesis Of Sporadic Chordoma: A Genetic And Functional‐Based Study
    320. Role Of The Transcriptional Coactivators Megakaryoblastic Leukemia Proteins 1 And 2 In Tumorigenesis
    321. Role Of Twist1 Transcription Factor In Thyroid Tumor Progression
    322. Role Of Vitamin D Signalling In Vascular Smooth Muscle Cells-Morphological And Molecular Study
    323. Rolle Der Histonmethyltransferase Suv39H1 In Zellulärer Seneszenz Und Ras-Induzierter Lymphomgenese
    324. Schwannomas, Bening Tumors With A Senescent Phenotype
    325. Selenium Concentrations For Maximisation Of Thioredoxin Reductase 2 Activity And Upregulation Of Its Gene Transcripts In Senescent Human Fibroblasts
    326. Selezione Bibliografica Su Polygonum Cuspidatum E Resveratrolo
    327. Self-Consumption: The Interplay Of Autophagy And Apoptosis
    328. Senescence
    329. Senescence Escape In Melanoma: Role Of Spleen Tyrosine Kinase Syk
    330. Senescence Induction In Cancer Cells
    331. Senescence , Apoptosis Or Autophagy?
    332. Senescence -Associated ß-galactosidase As A Senescence Biomarker Showed In Rat Hippocampus
    333. Seno-Destructive Smooth Muscle Cells In The Ascending Aorta Of Patients With Bicuspid Aortic Valve Disease
    334. Senolytika-Současný Stav
    335. Sharp-1 Mediates P53-Dependent Cellular Senescence Through Antagonism Of Sirt1
    336. Similarities In Gene Expression Profiles During In Vitro Aging Of Primary Human Embryonic Lung And Foreskin Fibroblasts
    337. Sirt6 Deacetylates H3K18Ac At Pericentric Chromatin To Prevent Mitotic Errors And Cellular Senescence
    338. Site‐Specific N‐Linked Glycosylation Analysis On The Human Salivary Mucin Muc5B Using Precursor Ion Discovery On The Caplc Q‐Tof System
    339. Small Molecules As Modulators Of Mitotic Arrest And Senescence In Cancer
    340. Some New Insights On The Molecular Structure And Function Of Heparan Sulfate
    341. Stem Cell Passage Affects Directional Migration Of Stem Cells In Electrotaxis
    342. Strategies For Future Histocompatible Stem Cell Therapy
    343. Stress-Induced (Premature) Senescence
    344. Stress-Induced Premature Senescence Or Stress-Induced Senescence -Like Phenotype: One In Vivo Reality, Two Possible Definitions?
    345. Stress-Induced Premature Senescence . Essence Of Life, Evolution, Stress, And Aging.
    346. Stromal Senescence By Prolonged Cdk4/6 Inhibition Potentiates Tumor Growth
    347. Structural And Functional Studies On Hyaluronan‐Protein Aggregates Produced In Vitro
    348. Study On Novel Physiological Function Of 1-Deoxynojirimycin Derived From Mulberry Leaves
    349. Studying The Role Of Heparin In The Formation Of Fgf1‐Fgfr2 Complexes Using Gel Chromatography
    350. Subcytotoxic H2O2 Stress Triggers A Release Of Tgf-ß1 Which Induces Biomarkers Of Cellular Senescence Of Human Diploid Fibroblasts
    351. Suppression Of Free-Radicals And Protection Against H2O2-Induced Oxidative Damage In Hpf-1 Cell By Oxidized Phenolic Compounds Present In Black Tea
    352. Suppression Of Proliferative Defects Associated With Processing-Defective Lamin A Mutants By Htert Or Inactivation Of P53
    353. Switching Off Immp2L Signaling Drives Senescence Via Simultaneous Metabolic Alteration And Blockage Of Cell Death
    354. Synergistic Induction Of The Senescence -Associated Genes By 5-Bromodeoxyuridine And At-Binding Ligands In Hela Cells
    355. Synthetic Lethality In Breast Cancer Cells: Genes Required For Tumor Survival
    356. Synthetic Oligopeptides As Cancer Cell Cycle Modulators
    357. Systemic Dysfunction Of Osteoblast Differentiation In Adipose-Derived Stem Cells From Patients With Multiple Myeloma
    358. Testosterone Deficiency Accelerates Neuronal And Vascular Aging Of Samp8 Mice: Protective Role Of Enos And Sirt1
    359. Tgf-ß Induced Cellular Senescene In Cancer Cells Is Reversible And Operates Via Two Separate And Independent Pathways
    360. The Analysis Of The Fibroblast Growth Factor Ligand‐Receptor Complex Using A Quartz Crystal Microbalance‐Dissipation
    361. The Dna Helicase Recql4 Is Required For Normal Osteoblast Expansion And Osteosarcoma Formation
    362. The Effect Of Stress Induced Premature Senescence On The Expression Of Heterogeneous Ribonucleoieoprotein
    363. The Effects Of Baicalin Against Uva-Induced Photoaging In Skin Fibroblasts
    364. The Effects Of Chronic And Acute Toxicological Exposures On The Expression Of The Tumor Suppressor P16Ink4A
    365. The Effects Of Human Intervertebral Disc Aggrecan On Neuronal And Endothelial Cell Growth
    366. The Effects Of Iron Chelators On The Phenotype Of Hpv-Positive Cervical Cancer Cells
    367. The Gap Between The Physiological And Therapeutic Roles Of Mesenchymal Stem Cells
    368. The Immunoregulatory Effects Of Cmv-Infection In Human Fibroblasts And The Impact On Cellular Senescence
    369. The Impact Of Long-Term In Vitro Expansion On The Senescence -Associated Markers Of Human Adipose-Derived Stem Cells
    370. The Microtubule-Associated Protein Prc1 Is A Potential Therapeutic Target For Lung Cancer
    371. The Molecular Evolution Of The Collagen X (C1Q/Tnfα) Supergene Family
    372. The Molecular Frame Of Pancreatic Carcinogenesis
    373. The Mrna Phenotype Of A Human Rpe Cell Line At Replicative Senescence
    374. The Novel Mkl Target Gene Myoferlin Modulates Expansion And Senescence Of Hepatocellular Carcinoma
    375. The Novel Mkl1/2 Dependent Target Gene Myoferlin Modulates Expansion And Senescence Of Hepatocellular Carcinoma
    376. The P53/Mir-17/Smurf1 Pathway Mediates Skeletal Deformities In An Age-Related Model Via Inhibiting The Function Of Mesenchymal Stem Cells
    377. The Pi3K/Akt/Mtor Pathway Is Implicated In The Premature Senescence Of Primary Human Endothelial Cells Exposed To Chronic Radiation
    378. The Possible Involvement Of The Receptor For Advanced Glycation End Products In Vascular Senescence In Diabetes
    379. The Regulation Of Signaling In Hematopietic Stem Cell Maintenance.
    380. The Reverse Transcription Inhibitor Abacavir Shows Anticancer Activity In Prostate Cancer Cell Lines
    381. The Role Of A-Type Lamins And Lap2A In Cellular Ageing Of Human Fibroblasts In Vitro
    382. The Role Of Cks Proteins In Cancer Development
    383. The Role Of Drosophila Bx42/Skip In Cell Cycle
    384. The Role Of Mutant Phosphoinositide 3-Kinase P110Alpha In Liver And Bile Duct Cancer
    385. The Role Of P53 In The Drug Resistance Phenotype Of Childhood Neuroblastoma
    386. The Role Of Polycomb Group Gene Bmi1 In The Development Of Prostate Cancer
    387. The Role Of Polyhomeotic In Polycomb Group-Mediated Regulation Of The Tumour Suppressor P16Ink4A
    388. The Role Of Proteoglycans In Regeneration And Plasticity
    389. The Role Of Sumoylation In Senescence
    390. The Role Of Vimentin Intermediate Filaments In The Physiology Of Adipocytes
    391. The Sand Rat (Psammomys Obesus Obesus) Model Of Spontaneous, Age-Related Intervertebral Disc Degeneration
    392. The Senescence Accelerated Mouse Prone 8 (Samp8): A Novel Murine Model For Cardiac Aging
    393. The Senescence -Associated Secretory Phenotype Mediates Oncogene-Induced Senescence In Pediatric Pilocytic Astrocytoma
    394. The Senescence -Associated Secretory Phenotype Regulates The Growth Behavior Of Pediatric Pilocytic Astrocytoma
    395. The Swi/Snf Atpases Are Required For Triple Negative Breast Cancer Cell Proliferation
    396. The Tumor Suppressive Role Of Wif1 In Glioblastoma
    397. The Twists And Turns Of Chromatin And Histone Modifications In Human Cells
    398. The Upregulation Of Toll-Like Receptor 3 Via Autocrine Ifn-beta Signaling Drives The Senescence Of Human Mesenchymal Stem Cells Through Jak1
    399. The Upregulation Of Toll-Like Receptor 3 Via Autocrine Ifn-Β Signaling Drives The Senescence Of Human Umbilical Cord Blood-Derived Mesenchymal Stem …
    400. The Use Of Sa‐Β‐Gal To Assess Cell Senescence In Intervertebral Disc Cells
    401. The Zo-1–Associated Y-Box Factor Zonab Regulates Epithelial Cell Proliferation And Cell Density
    402. Time-Dependently Expressed Markers And The Characterization For Premature Senescence Induced By Ionizing Radiation In Mcf7
    403. Topic 01–Atherosclerosis, Hemostasis, Inflammation, Age–A
    404. Transcriptional Changes Associated With Breast Cancer Occur As Normal Human Mammary Epithelial Cells Overcome Senescence Barriers And Become …
    405. Transcriptionally Regulated, Prostate-Targeted Gene Therapy For Prostate Cancer
    406. Transforming Growth Factor Β Triggers Two Independent-Senescence Programs In Cancer Cells
    407. Triethylene Tetramine, A Novel Ligand Of G-Quadruplex, Induces Senescence Of Mcf-7 Cells
    408. Ultrastructure Of Inclusion Bodies In Annulus Cells In The Degenerating Human Intervertebral Disc
    409. Understanding The Effect Of 1, 3-Butadiene On Human Lung Fibroblasts: Does Exposure To 1, 3-Butadiene Induce Senescence ?
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