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    EXCITOXICITY & THE BRAIN
    February 8, 2021
    PREVENTING SKIN AGING
    February 11, 2021
    1. brain polyamine levels are altered in Alzheimer’s disease
    2. polyamine transport, accumulation, and release in brain
    3. The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain
    4. polyamine catabolism is enhanced after traumatic brain injury
    5. polyamine metabolism in different pathological states of the brain
    6. Overview of the brain polyamine –stress-response: regulation, development, and modulation by lithium and role in cell survival
    7. polyamine metabolism and function in brain
    8. polyamine modification increases the permeability of proteins at the blood‐nerve and blood‐brain barriers
    9. Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and …
    10. Modification of biodistribution and brain uptake of copper bis (thiosemicarbazonato) complexes by the incorporation of amine and polyamine functional groups
    11. The antistress effect of ginseng total saponin and ginsenoside Rg3 and Rb1 evaluated by brain polyamine level under immobilization stress
    12. Pharmacological characterisation and autoradiographic distribution of polyamine -sensitive [3H] ifenprodil binding sites in the rat brain
    13. Attenuation of brain Edema, Blood-brain Barrier Breakdown, and injury Volume by Ifenprodil, a polyamine -Site N-Methyl-d-aspartate Receptor Antagonist, after …
    14. Contribution of polyamine oxidase to brain injury after trauma
    15. polyamine reutilization and turnover in brain
    16. brain .17.aspx”>Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression
    17. polyamine metabolism in brain tumours: diagnostic relevance of quantitative biochemistry
    18. Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain -specific mouse model of tuberous sclerosis complex
    19. polyamine uptake, binding and release in rat brain
    20. Arginase and arginine decarboxylase–where do the putative gate keepers of polyamine synthesis reside in rat brain ?
    21. polyamine metabolism in transient focal ischemia of rat brain
    22. Effects of MDL 72527, a specific inhibitor of polyamine oxidase, on brain edema, ischemic injury volume, and tissue polyamine levels in rats after temporary middle …
    23. Changes in polyamine levels in rat brain after systemic kainic acid administration: relationship to convulsant activity and brain damage
    24. Developmental regulation of the brain polyamine –stress-response
    25. In Situ Metabolomics of the Honeybee brain : The Metabolism of l-Arginine through the polyamine Pathway in the Proboscis Extension Response (PER)
    26. Maternal behavior as a regulator of polyamine biosynthesis in brain and heart of the developing rat pup
    27. Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex
    28. Depletion of 9L rat brain tumor cell polyamine content by treatment with D, L-α-difluoromethylornithine inhibits proliferation and the G1 to S transition
    29. Effect of polyamine depletion on chromatin structure in U-87 MG human brain tumour cells
    30. Regional brain polyamine levels in permanent focal cerebral ischemia
    31. … of superoxide dismutase at the blood‐nerve and blood‐brain barriers with retained enzymatic activity after covalent modification with the naturally occurring polyamine …
    32. Acute hypoxia increases ornithine decarboxylase activity and polyamine concentrations in fetal rat brain .
    33. polyamine synthesis in mammalian tissues. Isolation and characterization of spermidine synthase from bovine brain
    34. brain polyamine stress response: recurrence after repetitive stressor and inhibition by lithium
    35. Evidence that the Kennedy and polyamine pathways are dysregulated in human brain in cases of dementia with Lewy bodies
    36. polyamine synthesis in mammalian tissues: isolation and characterization of spermine synthase from bovine brain
    37. polyamine metabolism in a rat brain tumor cell line: its relationship to the growth rate
    38. polyamine biosynthesis in human fetal liver and brain
    39. Blood–brain Barrier Breakdown in Cold‐Injured brain Is Linked to a Biphasic Stimulation of Ornithine Decarboxylase Activity and polyamine Synthesis: Both Are …
    40. Autoradiographic Distribution and Characteristics of High‐ and Low‐Affinity polyamine ‐Sensitive [3H]Ifenprodil Sites in the Rat brain : Possible Relationship to …
    41. Changes in brain polyamine levels following head injury
    42. Radiation brain injury is reduced by the polyamine inhibitor α-difluoromethylornithine
    43. Effect of maternal deprivation on polyamine metabolism in preweanling rat brain and heart
    44. Developmental aspects of polyamine interconversion in rat brain
    45. Effect of ifenprodil, a polyamine site NMDA receptor antagonist, on brain edema formation following asphyxial cardiac arrest in rats
    46. Fungal Enzyme l-Lysine α-Oxidase Affects the Amino Acid Metabolism in the brain and Decreases the polyamine Level
    47. polyamine Concentrations in the brain of Vitamin B12-Deficient Rats
    48. Blood-brain barrier breakdown by cold injury. polyamine signals mediate acute stimulation of endocytosis, vesicular transport, and microvillus formation in rat cerebral …
    49. Increases in brain polyamine concentrations in chemical kindling and single convulsion induced by pentylenetetrazol in rats
    50. polyamine and aminoguanidine treatments to promote structural and functional recovery in the adult mammalian brain after injury: a brief literature review and …
    51. Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain
    52. Interaction of a polyamine analogue, 1, 19-bis-(ethylamino)-5, 10, 15-triazanonadecane (BE-4-4-4-4), with DNA and effect on growth, survival, and polyamine levels in …
    53. polyamine TURNOVER IN DIFFERENT REGIONS OF RAT brain 1
    54. Increased polyamine concentrations in the cerebrospinal fluid of patients with brain tumors
    55. Inhibitory role of ecdysone on neurogenesis and polyamine metabolism in the adult cricket brain
    56. Developmental changes in mouse brain polyamine metabolism
    57. polyamine metabolism in experimental brain tumors of rat
    58. polyamine metabolism in the brain and liver of the developing monkey
    59. Effect of immobilization stress on brain polyamine levels in spontaneously hypertensive and Wistar-Kyoto rats
    60. Cellular proliferation and infiltration following interstitial irradiation of normal dog brain is altered by an inhibitor of polyamine synthesis
    61. Effects of dl-α-methylornithine on proliferation and polyamine content of 9L rat brain tumor cells
    62. polyamine metabolism and glutamate receptor agonists‐mediated excitotoxicity in the rat brain
    63. polyamine effects on the NMDA receptor in human brain
    64. Kainate-induced seizure activity stimulates the polyamine interconversion pathway in rat brain
    65. polyamine levels in brain and plasma after acute restraint or water-immersion restraint stress in mice
    66. Regulatory interrelations between GABA and polyamines. I. brain GABA levels and polyamine metabolism
    67. THE EFFECT OF dl‐ALLYLGLYCINE ON polyamine AND GABA METABOLISM IN MOUSE brain
    68. Relationship between tissue polyamine levels and malignancy in primary brain tumors
    69. Dynamic and regional aspects of polyamine metabolism in the brain of trout (Salmo irideus Gibb.)
    70. Decreased cytotoxicity of aziridinylbenzoquinone caused by polyamine depletion in 9L rat brain tumor cells in vitro
    71. Chemotherapeutic choice of ranimustine or nimustine on the basis of regional polyamine levels in rat brain .
    72. Seizure activity-induced changes in polyamine metabolism and neuronal pathology during the postnatal period in rat brain
    73. Interrelationships between polyamines and nucleic acids. Changes of polyamine and nucleic acid concentrations in the growing fish brain (Salmo irideus Gibb.)
    74. Activity of ornithine decarboxylase (ODC) and polyamine levels as biochemical markers of malignancy in human brain tumors.
    75. Depletion of intracellular polyamine content does not alter the survival of 9L rat brain tumour cells after X-irradiation
    76. Two polyamine analogs (BE-4-4-4 and BE-4-4-4-4) directly affect growth, survival, and cell cycle progression in two human brain tumor cell lines
    77. The ability of polyamine analogues to induce Z-DNA structure in synthetic polynucleotides in vitro inversely correlates with their effects on cytotoxicity of cis …
    78. Neonatal polyamine depletion by α-difluoromethylornithine: effects on adenylyl cyclase cell signaling are separable from effects on brain region growth
    79. Regional distribution of ornithine decarboxylase activity and polyamine levels in experimental cat brain tumors
    80. Regional Heterogeneity of polyamine Effects on the N‐Methyl‐D‐Aspartate Receptor in Rat brain
    81. Influence of polyamine depletion caused by α-difluoromethylornithine, an enzyme-activated irreversible inhibitor of ornithine decarboxylase, on alkylation-and …
    82. Effects of anesthesia on polyamine metabolism and water content in the rat brain
    83. The polyamine synthesis inhibitor α-difluoromethylornithine is neuroprotective against N-methyl-D-aspartate-induced brain damage in vivo
    84. Effects of felbamate on brain polyamine changes following transient cerebral ischemia in the Mongolian gerbil
    85. Effect of eliprodil, an NMDA receptor antagonist acting at the polyamine modulatory site, on local cerebral glucose use in the rat brain
    86. The rationale for the localization of polyamine pathway enzymes in the brain
    87. polyamine Regulation of Protein Phosphorylation in the brain of the Tobacco Hornworm, Manduca sexta
    88. Effects of bilateral olfactory bulb ablations on the polyamine levels in rat brain
    89. Lithium exerts a time-dependent and tissue-selective attenuation of the dexamethasone-induced polyamine response in rat brain and liver
    90. Study of the Characterization of Partial Purified polyamine Oxidase from Sheep’s brain Tissue
    91. Changes in mitochondrial structure and function in 9L rat brain tumor cells treated in vitro with α-difluoromethylornithine, a polyamine biosynthesis inhibitor
    92. Modulation of A1 adenosine receptor function in rat brain by the polyamine , spermine
    93. Evaluation of polyamine levels in cerebrospinal fluid of children with brain tumors
    94. Effect of treatment with difluoromethylornithine on polyamine and spectrin breakdown levels in neonatal rat brain
    95. Trophic control of the ornithine decarboxylase/polyamine system in neonatal rat brain regions: lesions caused by 6-hydroxydopamine produce effects selective for …
    96. Decreased cell kill of vincristine and methotrexate against 9L rat brain tumor cells in vitro caused by α-difluoromethylornithine-induced polyamine depletion
    97. Correction: Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and …
    98. Effects of the polyamine analogs BE-3-7-3, 3-8-3, and BE-3-8-3 on human brain tumor cell growth and survival.
    99. Pentylenetetrazol-induced kindling stimulates the polyamine interconversion pathway in rat brain
    100. Effect of kainate-induced seizure activity on the polyamine interconversion pathway in juvenile rat brain
    101. Alterations in methylation affect polyamine biosynthesis in mouse brain
    102. Reversal by polyamine of the aluminum-induced inhibition of hexokinase from human brain
    103. Chemotherapeutic targeting of etoposide to regions of the brain on the basis of polyamine level
    104. polyamine ‐enhanced NMDA ‐induced behavioural changes and FOS‐immunoreactivity in rat brain
    105. Effects of fructose-1, 6-bisphosphate on brain polyamine biosynthesis in a model of transient cerebral ischemia
    106. Erratum: Dysregulation of multiple metabolic networks related to brain transmethylation and polyamine pathways in Alzheimer disease: A targeted metabolomic and …
    107. Thyroxine effects on polyamine metabolism in rat cerebellum and brain cortex during postnatal development.
    108. Plasma polyamine changes and possible effects on hypofunctional NMDA receptor found in schlzophrenic brain
    109. NMDA receptors mediate activation of polyamine synthesis and blood-brain barrier breakdown after cold injury
    110. polyamine acetylation in the developing and aging mouse brain
    111. Effect of lithium on the polyamine Response in brain after stress
    112. Interaction of rigid polyamine analogues with the NMDA receptor complex from rat brain
    113. Fos‐B expression is required for polyamine ‐induced increase in nuclear activator protein‐1 DNA binding in discrete structures of murine brain
    114. Enhanced Uptake of [3 H] Spermidine by 9L Rat brain Tumors After Direct Intratumoral Infusion of Inhibitors of Enzymes of the polyamine Biosynthetic Pathway
    115. … dependence of the potentiation of 1, 3-bis (2-chloroethyl)-1-nitrosourea cytotoxicity caused by α-difluoromethylornithine-induced polyamine depletion in 9L rat brain …
    116. Effect of long-term space flight on polyamine levels in the rat brain
    117. Reversible changes in goldfish brain polyamine concentrations and synthetic enzymes after cold exposure
    118. polyamine contents in the brain and liver of rats during acclimatization to the cold
    119. A New Target for Treatment of Schizophrenia: Agmatine and brain polyamine System
    120. Ornithine decarboxylase activity and polyamine concentrations in fetal rat brain : response to chronic hypoxic-hypoxia and/or carbon monoxide-hypoxia
    121. Possible involvement of humoral regulation in the effects of elevated cerebral 4‐aminobutyric acid levels on the polyamine metabolism in brain
    122. Study of ocular tissue changes, brain GABA and polyamine levels in rats exposed to carbon disulfide.
    123. Effect of melatonin administration on the immobilization stress-induced polyamine responses in brain and gastrointestinal tract
    124. Pretreatment with the polyamine analog 1, 19-bis-(ethylamino)-5, 10, 15-triazanonadecane (BE-4-4-4-4) inhibits etoposide cytotoxicity in U-251 MG (NCI) human brain …
    125. polyamine binding sites in the rat brain hippocampus plasma membranes: MK 801 does not influence the binding process
    126. Spermine and L-NAME pretreatment effects on polyamine and nitric oxide metabolism in rat brain during seizures
    127. Analysis of polyamine Level in Certain brain Regions of Aging Rats
    128. Contribution of polyamine oxidase to brain injury after
    129. … 2-carboxypiperazin-4-yl) propyl-1-phosphonic acid ([3H] CPP) binding by ligands acting at the glycine and the polyamine sites of the rat brain NMDA receptor complex
    130. polyamine Uptake by Malignant brain Tumour Xenografts in Nude Mice
    131. brain polyamine Metabolism During Soman-induced Status Epilepticus. Modulation with alpha-DFMO.
    132. polyamine modulation of phosphorylation of channel-forming cytosolic protein in bovine brain
    133. Pentylenetetrazol-induced kindling stimulates polyamine acetylation in rat brain
    134. … for Treatment of Alzheimer Disease by polyamine Modification of Antioxidant Enzymes and Neurotrophic Factors to Increase Their Permeability at the Blood-brain …
    135. polyamine acetylation in rat brain during N-ethyl-N-nitrosourea-induced cerebral carcinogenesis
    136. Influences of Hydrocortisone, DHEA, Estradiol and Testosterone on the polyamine Metabolism of Mouse brain , Kidney, Liver and Intestine
    137. Anti-stress effects of the ginsenosides Rg3 and R bl on the changes in brain polyamine levels after immobilization stress
    138. Effect of Melatonin on brain polyamine Contents and Hippocampal Neuronal Damage after Transient Global Ischemia in Mongolian Gerbil
    139. Choice of vincristine or 6-mercaptopurine on the basis of polyamine level in tumor-bearing regions of the brain
    140. Modulation of the NMDA receptor by polyamines
    141. Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines
    142. Molecular basis of positive allosteric modulation of GluN2B NMDA receptors by polyamines
    143. Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor
    144. Role of polyamines and NMDA receptors in ethanol dependence and withdrawal
    145. The involvement of the polyamines binding sites at the NMDA receptor in creatine-induced spatial learning enhancement
    146. polyamines contribute to ethanol withdrawal‐induced neurotoxicity in rat hippocampal slice cultures through interactions with the NMDA receptor
    147. Effects of polyamines on NMDA -induced currents in rat hippocampal neurons: a whole-cell and single-channel study
    148. polyamines modulate the neurotoxic effects of NMDA in vivo
    149. The role of hydrophobic interactions in binding of polyamines to non NMDA receptor ion channels
    150. glutamate and glycine co-activate while polyamines merely modulate the NMDA receptor complex.
    151. The polyamines, spermine and spermidine, negatively modulate N-methyl-d-aspartate (NMDA ) and quisqualate receptor mediated responses in vivo: Cerebellar …
    152. polyamines and the NMDA receptor: Modifying intrinsic activities with aromatic substituents
    153. Lack of evidence for direct involvement of NMDA receptors or polyamines in blood–brain barrier injury after cerebral ischemia in rats
    154. polyamines and NMDA receptors modulate pericapillary astrocyte swelling following cerebral cryo-injury in the rat
    155. Motor depressant effects of systemically administered polyamines in mice: involvement of central NMDA receptors
    156. Histamine release from mast cells by polyamines: an NMDA receptor-mediated event?
    157. polyamines modulate [3H] L-689 binding to the glycine site of the NMDA receptor from rat brain
    158. polyamines modulate events mediated by the N-methyl-D-aspartate (NMDA ) receptor complex through an ifenprodil-insensitive pathway: in vivo measurements of …
    159. Histamine and NMDA -receptors in the hippocampus: polyamines and intracellular binding site.
    160. Differential effects of linear and cyclic polyamines on NMDA receptor activities
    161. Comparison of anti-amnesia properties of NMDA -receptor” fast” blockers and polyamines
    162. Do polyamines regulate the NMDA inhibition of muscarinic receptor-induced phosphoinositide turnover in guinea pig brain ?
    163. Anatomical and developmental heterogeneity of the effects of polyamines on the NMDA receptor.
    164. The actions of polyamines on NMDA receptors: Electrophysiological and molecular studies.
    165. The actions of polyamines on NMDA receptors: Electrophysiological and molecular studies
    166. polyamines and the NMDA receptor: Modifying intrinsic activities with aromatic substituents pp 2837–2841
    167. Antidepressant-like actions of the polyamine site NMDA antagonist, eliprodil (SL-82.0715)
    168. Characterization of polyamines having agonist, antagonist, and inverse agonist effects at the polyamine recognition site of the NMDA receptor
    169. Synthetic analogues of conantokin‐G: NMDA antagonists acting through a novel polyamine ‐coupled site
    170. An allosteric interaction between the NMDA receptor polyamine and ifenprodil sites in rat cultured cortical neurones
    171. Selective antagonism of native and cloned kainate and NMDA receptors by polyamine -containing toxins.
    172. polyamine analogue regulation of NMDA MK-801 binding: A structure− activity study
    173. Characterisation of a functional polyamine site on rat mast cells: association with a NMDA receptor macrocomplex
    174. Inhibition of the polyamine system counteracts β-amyloid peptide-induced memory impairment in mice: involvement of extrasynaptic NMDA receptors
    175. polyamine -like actions of peptides derived from conantokin-G, an N-methyl-D-aspartate (NMDA ) antagonist
    176. Molecular features associated with polyamine modulation of NMDA receptors
    177. Effects of acamprosate and some polyamine site ligands of NMDA receptor on short-term memory in rats
    178. Blockade of the polyamine site of NMDA receptors produces antinociception and enhances the effect of morphine, in mice
    179. Effects of ifenprodil, a polyamine site NMDA receptor antagonist, on reperfusion injury after transient focal cerebral ischemia
    180. Impact of polyamine Analogs on the NMDA Receptor
    181. Radioligand binding studies reveal agmatine is a more selective antagonist for a polyamine -site on the NMDA receptor than arcaine or ifenprodil
    182. Combined stimulation of the glycine and polyamine sites of the NMDA receptor attenuates NMDA blockade-induced learning deficits of rats in a 14-unit T-maze
    183. polyamine -like actions of aminoglycosides and aminoglycoside derivatives at NMDA receptors
    184. polyamine and ifenprodil interactions with the NMDA receptor’s glycine site
    185. Effect of ifenprodil, a polyamine site NMDA receptor antagonist, on brain edema formation following asphyxial cardiac arrest in rats
    186. A critical importance of polyamine site in NMDA receptors for neurite outgrowth and fasciculation at early stages of P19 neuronal differentiation
    187. Potent analgesia induced in rats by combined action at PCP and polyamine recognition sites of the NMDA receptor complex
    188. Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors
    189. Design, synthesis, and evaluation of polyamine -memantine hybrids as NMDA channel blockers
    190. … of the antinociceptive activity of combinations of competitive and non-competitive NMDA antagonists with agents acting at allosteric-glycine and polyamine receptor …
    191. polyamine effects on the NMDA receptor in human brain
    192. polyamine regulation of the NMDA receptor complex as a target in drug development
    193. Exploring the polyamine regulatory site of the NMDA receptor: a parallel synthesis approach
    194. polyamine -enhanced NMDA receptor activity: effect of ethanol
    195. New polyamine -sensitive inhibitors of the NMDA receptor: Syntheses and pharmacological evaluation
    196. Developmental differences in antagonism of NMDA toxicity by the polyamine site antagonist ifenprodil
    197. Chronic treatment with the uncompetitive NMDA receptor antagonist memantine influences the polyamine and glycine binding sites of the NMDA receptor complex in …
    198. Blockade by polyamine NMDA antagonists related to ifenprodil of NMDA ‐induced synthesis of cyclic GMP, increases in calcium and cytotoxicity in cultured neurones
    199. Neuroprotective potential of the polyamine site-directed NMDA receptor antagonists—ifenprodil and eliprodil
    200. SL 82.0715, an NMDA antagonist acting at the polyamine site, does not induce neurotoxic effects on rat cortical neurons
    201. polyamine sulfonamides with NMDA antagonist properties are potent calmodulin antagonists and cytotoxic agents
    202. [125I] Ifenprodil: a convenient radioligand for binding and autoradiographic studies of the polyamine -sensitive site of the NMDA receptor
    203. NMDA receptor subtype selectivity: eliprodil, polyamine spider toxins, dextromethorphan, and desipramine selectively block NMDA ‐evoked striatal acetylcholine but …
    204. Modification of the philanthotoxin-343 polyamine moiety results in different structure-activity profiles at muscle nicotinic ACh, NMDA and AMPA receptors
    205. Inverse agonists at the polyamine -sensitive modulatory site of the NMDA receptor: 50-fold increase in potency by insertion of an aromatic ring into an alkanediamine …
    206. The polyamine diaminodecane (DA-10) produces a voltage-dependent flickery block of single NMDA receptor channels
    207. Effect of eliprodil, an NMDA receptor antagonist acting at the polyamine modulatory site, on local cerebral glucose use in the rat brain
    208. Ornithine decarboxylase inhibition or NMDA receptor antagonism reduce cortical polyamine efflux associated with dialysis probe implantation
    209. Effects of the polyamine spermidine on NMDA -induced arterial hypertension in freely moving rats
    210. A photoaffinity probe for the polyamine site regulating the NMDA receptor
    211. Conantokin-G and its analogs: Novel probes of the NMDA receptor-associated polyamine site
    212. Regulation of polyamine and magnesium inhibition of the N-methyl-d-aspartate (NMDA ) receptor ionophore complex
    213. The putative polyamine antagonists ifenprodil and SL 82.0715 enhance dopamine efflux from rat striatal slices independent of NMDA receptor activation
    214. polyamine ‐enhanced NMDA ‐induced behavioural changes and FOS‐immunoreactivity in rat brain
    215. polyamine conjugates as selective NMDA inhibitors and anti-cancer drugs
    216. Intracellular polyamine levels are involved in NMDA ‐evoked nitric oxide production in chick retina cells
    217. polyamine potentiation and inhibition of NMDA -mediated increases of intracellular free Ca2+ in cultured chick cortical neurons
    218. polyamine -sensitive binding of [125I] ifenprodil in washed, frozen-thawed synaptic membranes: evidence for high affinity binding requiring an open NMDA channel
    219. Aminooxy-analogues of spermidine: new partial agonists and antagonists at the polyamine site of the rat hippocampal NMDA receptor complex
    220. Plasma polyamine changes and possible effects on hypofunctional NMDA receptor found in schlzophrenic brain
    221. Chronic neonatal blockade of NMDA receptor does not affect developmental polyamine metabolism but results in altered response to the excitotoxic induction of …
    222. Central effects of SL 82.0715, an antagonist of polyamine site of the NMDA receptor complex.
    223. NMDA receptors mediate activation of polyamine synthesis and blood-brain barrier breakdown after cold injury
    224. Interaction of rigid polyamine analogues with the NMDA receptor complex from rat brain
    225. QSAR studies combined with DFT-calculations and Molecular docking of polyamine -sensitive inhibitors of the NMDA receptor
    226. An alternative approach to understand schizophrenia: polyamine hypothesis through NMDA receptors
    227. polyamine conjugates as selective NMDA inhibitors and anti-cancer drugs
    228. Lack of antidepresant-like activity of some ligands of polyamine binding sites of NMDA receptors in models of depression
    229. Complex polyamine effects on [3H] MDL 105,519 binding to the NMDA receptor glycine site.
    230. … of [3H] 3-((±)-2-carboxypiperazin-4-yl) propyl-1-phosphonic acid ([3H] CPP) binding by ligands acting at the glycine and the polyamine sites of the rat brain NMDA …
    231. polyamine -phospholipid complex blocks NMDA -activated currents in vitro
    232. Screening for novel ligands at a polyamine recognition domain on the N-methyl-D-aspartate (NMDA ) receptor complex.
    233. polyamine spider toxins and NMDA receptors: structural basis for channel block and binding of argiotoxin636
    234. Characterization of the polyamine site associated with the N-methyl-D-aspartate (NMDA ) receptor/ionophore complex.
    235. polyamine _Site_in_N_Methyl_D_Aspartate.1187.aspx”>ROLE OF polyamine SITE IN N-METHYL-D-ASPARTATE (NMDA ) RECEPTORMEDIATED NEUROTOXICITY OF CULTURED CORTICAL NEURONS.
    236. (sup 125 I) Ifenprodil: a convenient radioligand for binding and autoradiographic studies of the polyamine -sensitive site of the NMDA receptor
    237. Ifenprodil and SL 82.0715 antagonize the effects of NMDA via a polyamine -sensitive modulatory site
    238. polyamine -dependent facilitation of postsynaptic AMPA receptors counteracts paired-pulse depression
    239. Targets of polyamine dysregulation in major depression and suicide : activity-dependent feedback, excitability, and neurotransmission
    240. brain .17.aspx”>Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression
    241. The side effects of antimalarial drugs indicates a polyamine involvement in both schizophrenia and depression
    242. COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines
    243. depression of polyamine synthesis in L1210 leukemic mice during treatment with a potent antileukemic agent, 5-azacytidine
    244. Lack of antidepresant-like activity of some ligands of polyamine binding sites of NMDA receptors in models of depression
    245. Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers
    246. Global gene expression profiling of the polyamine system in suicide completers
    247. Evidence of altered polyamine concentrations in cerebral cortex of suicide completers
    248. suicide and the polyamine system
    249. Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide
    250. Targets of polyamine dysregulation in major depression and suicide : activity-dependent feedback, excitability, and neurotransmission
    251. Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide
    252. Effects of the suicide inhibitors of arginine and ornithine decarboxylase activities on organogenesis, growth, free polyamine and hydroxycinnamoyl putrescine levels in …
    253. Susceptibility of Microsporum and Trichophyton species to suicide inhibitors of polyamine biosynthesis
    254. polyamine ‐mediated regulation of S‐adenosylmethionine decarboxylase expression in mammalian cells: Studies using 5′‐{[(Z)‐4‐amino‐2‐butenyl]methylamino} …
    255. Involvement of the polyamine System in suicide
    256. polyamines and suicide risk
    257. polyamines, Hydroxycinnamoylputrescines, and Root Formation in Leaf Explants of Tobacco Cultivated in Vitro: Effects of the suicide Inhibitors of Putrescine …
    258. Oxidation of polyamines and brain injury
    259. Age-related changes in polyamines in memory-associated brain structures in rats
    260. polyamines in the brain : distribution, biological interactions, and their potential therapeutic role in brain ischaemia
    261. Limited blood‐brain barrier transport of polyamines
    262. The role of glia in stress: polyamines and brain disorders
    263. polyamines in human brain : regional distribution and influence of aging
    264. polyamines in the basal ganglia of human brain . Influence of aging and degenerative movement disorders
    265. Effect of deltamethrin on regional brain polyamines and behaviour in young rats
    266. A novel role for polyamines in adult neurogenesis in rodent brain
    267. Neuronal and glial responses to polyamines in the ischemic brain
    268. The regional distribution of the polyamines spermidine and spermine in brain
    269. The dynamics of synthesis and degradation of polyamines in normal and regenerating rat liver and brain
    270. Short biodegradable polyamines for gene delivery and transfection of brain capillary endothelial cells
    271. A quantitative GC‐MS method for three major polyamines in postmortem brain cortex
    272. polyamines in brain tumor therapy
    273. polyamines in human brain tumors
    274. polyamines stimulate mitochondrial calcium transport in rat brain
    275. Block of native Ca (2+)‐permeable AMPA receptors in rat brain by intracellular polyamines generates double rectification.
    276. Synthesis and biological evaluation of boron-containing polyamines as potential agents for neutron capture therapy of brain tumors
    277. Blood brain barrier breakdown in brain edema following cold injury is mediated by microvascular polyamines
    278. Boron-containing polyamines as DNA targeting agents for neutron capture therapy of brain tumors: Synthesis and biological evaluation
    279. stress-induced dynamic changes in mouse brain polyamines. Role in behavioral reactivity
    280. Inhibition of Na, K-ATPase from chick brain by polyamines
    281. brain polyamines are controlled by N-methyl-D-aspartate receptors during ischemia and recirculation.
    282. Differential response of rat brain polyamines to convulsant agents
    283. Cellular and subcellular rat brain spermidine synthase expression patterns suggest region‐specific roles for polyamines, including cerebellar pre‐synaptic function
    284. Differential responses of regional brain polyamines followingin utero exposure to synthetic pyrethroid insecticides: A preliminary report
    285. polyamines in the developing mouse brain
    286. Changes in concentration of polyamines in the developing mouse brain
    287. polyamines+brain +&ots=g5N0UwYBfz&sig=PnJOjebl9NetKHAbV3_nOOeMUVg”>polyamines and brain Tumors 1, 2
    288. Glia and glial polyamines. Role in brain function in health and disease
    289. Depletion of intracellular polyamines may alter DNA conformation in 9L rat brain tumor cells
    290. polyamines mediate the reversible opening of the blood-brain barrier by the intracarotid infusion of hyperosmolal mannitol
    291. polyamines contribute to calcium-stimulated release of aspartate from brain particulate fractions
    292. On the turnover of polyamines spermidine and spermine in mouse brain and other organs
    293. polyamines: DEVELOPMENTAL ALTERATIONS IN REGIONAL DISPOSITION AND METABOLISM IN RAT brain 1
    294. Metabolism of polyamines and oxidative stress in the brain of cholestatic rats
    295. Interrelations between polyamines and nucleic acids: changes of polyamine and nucleic acid concentrations in the developing rat brain
    296. … of growth sparing during neonatal nutritional deprivation or enhancement: ornithine decarboxylase, polyamines, and macromolecules in brain regions and heart
    297. Effects of polyamines on the uptake of neurotransmitters by rat brain synaptosomes
    298. polyamines allosterically modulate [3H] nitrendipine binding to the voltage-sensitive calcium channel in rat brain
    299. polyamines and Ca2+ Mediate Hyperosmolal Opening of the Blood‐brain Barrier: In Vitro Studies in Isolated Rat Cerebral Capillaries
    300. Accumulation of exogenous polyamines in gerbil brain after ischemia
    301. Toxic effects of putrescine in rat brain : polyamines can be involved in the action of excitotoxins
    302. polyamines and nucleic acid metabolism during development of chick embryo brain
    303. Decreased cytotoxicity of cis-diamminedichloroplatinum (II) by α-difluoromethylornithine depletion of polyamines in 9L rat brain tumor cells in vitro
    304. Regulation of the phosphoinositide cascade by polyamines in brain
    305. Relationships between GABA and polyamines in developing rat brain
    306. Analysis of dansyl derivatives of di-and polyamines in mouse brain , human serum and duodenal biopsy specimens by high-performance liquid chromatography on a …
    307. Analysis of histidine-containing dipeptides, polyamines, and related amino acids by high-performance liquid chromatography: Application to guinea pig brain
    308. Characterization of serotonin receptors in fish brain : polyamines inhibit the binding process
    309. Regulatory interrelations between GABA and polyamines. I. brain GABA levels and polyamine metabolism
    310. Effects of polyamines on calcium‐dependent rat brain phosphatidylinositol‐phosphodiesterase
    311. Role of polyamines in experience-dependent brain plasticity
    312. The research of role of non ureotelic arginases in polyamines biosynthesis in brain and kidney in vitro
    313. Effect of polyamines on the stability of brain -cortex ribosomes
    314. Interrelationships between polyamines and nucleic acids. III. Metabolic and autoradiographic studies of putrescine in mouse brain
    315. polyamines of the human brain during normal fetal and postnatal growth and during postnatal malnutrition
    316. Inhibition of glutamate Dehydrogenase in brain Mitochondria and Synaptosomes by Mg2+ and polyamines: A Possible Cause for Its Low In Vivo Activity
    317. Effect of dibutyltin dilaurate on regional brain polyamines in rats
    318. Interrelationships between polyamines and nucleic acids. Changes of polyamine and nucleic acid concentrations in the growing fish brain (Salmo irideus Gibb.)
    319. polyamines increase in the brain stem and cerebellum following labyrinthectomy.
    320. CSF polyamines: Potential as brain tumor markers
    321. Effects of gestational or neonatal treatment with alpha-difluoromethylornithine on ornithine decarboxylase and polyamines in developing rat brain and on adult rat …
    322. Effects of polyamines on proline endopeptidase activity in rat brain
    323. Lack of evidence for direct involvement of NMDA receptors or polyamines in blood–brain barrier injury after cerebral ischemia in rats
    324. polyamines in rat brain extracellular space after ischemia
    325. polyamines in brain and heart of the neontal rat: Effects of inhibitors of ornithine decarboxylase and spermidine synthase
    326. Ornithine decarboxylase and polyamines in developing rat brain and heart: Effects of perinatal hypothyroidism
    327. Effect of l-arginine on metabolism of polyamines in rat’s brain with extrahepatic cholestasis
    328. Acetylation of polyamines in mouse brain : subcellular and regional distribution
    329. Complex interactions between polyamines and calpain‐mediated proteolysis in rat brain
    330. Cerebrospinal fluid polyamines: biochemical markers of malignant childhood brain tumors
    331. Blood levels of polyamines in patients with brain tumor: Special reference to relationship between blood levels of polyamines and histological finding, extension as …
    332. The biosynthesis of polyamines in the brain of audiogenic seizure‐susceptible and‐resistant deermice
    333. polyamines Differentially Inhibit Cyclic AMP‐Dependent Protein Kinase‐Mediated Phosphorylation in the brain of the Tobacco Hornworm, Manduca sexta
    334. Ontogeny of polyamines in relation to nucleic acids in brain and spinal cord of the developing human fetus
    335. Stimulation of brain lipase activity by polyamines. Comparison with the effect of ACTH
    336. High-resolution capillary gas chromatography in combination with mass spectrometry for quantification of three major polyamines in postmortem brain cortex
    337. polyamines modulate [3H] L-689 binding to the glycine site of the NMDA receptor from rat brain
    338. Effects of polyamines on amino acid incorporation into protein by cerebral and cerebellar as well as “Neuronal” and “glial” nuclei of rat brain
    339. Metabolism of polyamines in normal and scrapie‐affected mouse brain and spleen
    340. Increased brain concentrations of polyamines in rats with encephalopathy due to a galactosamine-induced fulminant hepatic failure
    341. Multiple phosphorylation of pp30, a rat brain polyribosomal protein, sensitive to polyamines and corticotropin
    342. The effect of polyamines on the enzymes of the 4-aminobutyric acid metabolism in mouse brain in vitro
    343. Biosynthesis of polyamines in mouse brain : Effects of methionine sulfoximine and adenosylhomocysteine
    344. Acetylation of polyamines in chicken brain and retina.
    345. Red blood cell polyamines in brain tumour patients
    346. Diurnal levels of polyamines and activities of ornithine and S-adenosyl-l-methionine decarboxylases in mouse brain
    347. Phosphatidylinositol‐4‐phosphate kinase from rat brain : Activation by polyamines and inhibition by phosphatidylinositol 4, 5‐bisphosphate
    348. Role of polyamines in the Control of the Immune Response in the brain
    349. Stabilization of neuronal microtubules by polyamines and transglutaminase: its roles in brain function
    350. polyamines and the regulation of protein synthesis in brain .
    351. brain polyamines and aggressive behavior of isolated mice
    352. Rat brain polyamines: an analytical method validation
    353. Influence of the naturally occurring polyamines spermine, spermidine and putrescine on the kinetic properties of acetylcholinesterase. Comparative studies with the …
    354. polyamines IN THE NORMALLY DEVELOPING MALE AND FEMALE MOUSE brain .
    355. … characterization of the binding of (+)-5-methyl-10, 11-dihydro-5H-dibenzo [a, d] cyclohepten-5, 10-imine ([3H] MK-801) in rat brain : regional effects of polyamines.
    356. Determination of blood polyamines in patients with brain tumor-with special reference to relationship between varieties of tumors and concentrations of blood …
    357. Electrophysiological studies on the brain : Effects of nucleotide and tryptophan metabolites as modified by polyamines in normal and psychotic subjects.
    358. Monoamine oxidase activity and brain levels of histamine and polyamines in various extreme exposures
    359. The Control of Casein Kinase II Activity and Protein Phosphorylation in the brain of ManducaSexta by polyamines
    360. [3H]MK‐801 Binding to N‐Methyl‐d‐Aspartate Receptors Solubilized from Rat brain : Effects of Glycine Site Ligands, polyamines, Ifenprodil, and Desipramine
    361. Do polyamines regulate the NMDA inhibition of muscarinic receptor-induced phosphoinositide turnover in guinea pig brain ?
    362. … between abilities of a variety of polyamines to increase activator protein-1 DNA binding and to inhibit [3H] spermidine transport in nuclear fractions of murine brain
    363. Accumulation of Exogenous polyamines in Gerbil brain After lschemia
    364. Free and acetylated polyamines in cyst fluids of brain tumors
    365. CSF polyamines in childhood brain tumors.
    366. Variations in red blood cell polyamines in brain tumour patients treated with stereotactic radiosurgery
    367. Modulation by polyamines of the phosphorylation of the channel-forming cytosol protein of bovine brain
    368. The levels of polyamines in autopsy materials of some structures of brain lymbic system and reticular formation of patients with schizophrenia
    369. The levels of polyamines in autopsy materials of some structures of brain lymbic system and reticular formation of patients with schizophrenia
    370. Effect of hyperoxia on content of the polyamines spermine and spermidine in rat brain and liver
    371. Spermine and spermidine polyamines in the brain and liver of rats under hyperoxic action
    372. Improved analytical procedure for the measurements of selected biogenic polyamines by HPLC following dabsyl derivatisation in brain tissue
    373. Determination of polyamines in samples of human brain , spinal cord, CSF, muscle and muscle microdialysate by precolumn derivatization with 9-fluorenylmethyl …
    374. Measurement of blood polyamines in patients with brain tumor–special reference to relationship between the blood levels of spermidine and spermine, and …
    375. Activation of brain mitochondrial Ca2+ uptake by polyamines and by Ca2+
    376. Activation of brain mitochondrial Ca sup 2+ uptake by polyamines and by Ca sup 2+
    377. Metabolism of polyamines in rats’ brain with extrahepatic cholestasis
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