COLD SHOCK PROTEINS
February 21, 2022NOREPINEPHRINE
February 21, 2022- Hematopoietic Stem cell exhaustion impacted by p18INK4C and p21Cip1/Waf1 in opposite manners
- mTOR mediates Wnt-induced epidermal Stem cell exhaustion and aging
- Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis
- The Polycomb group gene Ezh2 prevents hematopoietic Stem cell exhaustion
- Relationships between Stem cell exhaustion , tumour suppression and ageing
- Stem cell exhaustion and leukemogenesis
- Progeria of Stem cells: Stem cell exhaustion in Hutchinson-Gilford progeria syndrome
- Short telomeres and Stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice
- Genetic regulation of hematopoietic Stem cell exhaustion during development and growth
- Could metabolic syndrome, lipodystrophy, and aging be mesenchymal Stem cell exhaustion syndromes?
- … ‐up of recipients of allogeneic bone marrow grafts reveals no progressive telomere shortening and provides no evidence for haematopoietic Stem cell exhaustion
- Pre-CFU-S quiescence and Stem cell exhaustion after cytostatic drug treatment: protective effects of the inhibitory peptide pGlu-Glu-Asp-Cys-Lys (pEEDCK)
- … be the intracellular determinants of longevity implicated in the progeric influence of obesity: Insulin, IGF-1, and leptin may all conspire to promote Stem cell exhaustion
- Stem cell exhaustion and atherosclerosis
- Hematopoietic Stem cell Quiescence Maintained by p21cip1/waf1
- Stem cell aging: what bleach can teach
- Growth signaling at the nexus of Stem cell life and death
- p21 loss compromises the relative quiescence of forebrain Stem cell proliferation leading to exhaustion of their proliferation capacity
- Stem cells and the rate of living
- DNA repair is limiting for haematopoietic Stem cells during ageing
- A Limited Role for p21Cip1/Waf1 in Maintaining Normal Hematopoietic Stem cell Functioning
- Deconstructing Stem cell self-renewal: genetic insights into cell -cycle regulation
- Does Stem cell exhaustion result from combining hematopoietic
- Signaling circuitries controlling Stem cell fate: to be or not to be
- Epigenetic control of hematopoietic Stem cell aging the case of Ezh2
- Stem cell exhaustion due to Runx1 deficiency is prevented by Evi5 activation in leukemogenesis
- The p53 tumor suppressor protein is a critical regulator of hematopoietic Stem cell behavior
- Loss of Foxo3a In FA Mice Leads to Hematopoietic Stem cell exhaustion That Can Be Attenuated by Natural Anti-Oxidant Quercetin.
- Understanding the Impact of Inflammation on Hematopoietic Stem Cells.
- Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and Stem cell loss
- Accumulation of DNA damage in hematopoietic Stem and progenitor cells during human aging
- Cellular aging leads to functional heterogeneity of hematopoietic Stem cells: a modeling perspective
- Balancing dormant and self-renewing hematopoietic Stem cells
- Telomere length dynamics in normal hematopoiesis and in disease states characterized by increased Stem cell turnover
- Controlling Stem cell proliferation: CKIs at work
- Cellular memory and hematopoietic Stem cell aging
- Enrichment of hematopoietic Stem cells with SLAM and LSK markers for the detection of hematopoietic Stem cell function in normal and Trp53 null mice
- Impaired hematopoietic Stem cell functioning after serial transplantation and during normal aging
- A dual role of p21 in Stem cell aging
- Mechanisms of Stem cell ageing
- Intrinsic and extrinsic control of haematopoietic Stem–cell self-renewal
- Runx family genes, niche, and Stem cell quiescence
- The haematopoietic Stem cell niche: new insights into the mechanisms regulating haematopoietic Stem cell behaviour
- Advances in hematopoietic Stem cell research through mouse genetics
- DNA repair is crucial for maintaining hematopoietic Stem cell function
- Regulation of hematopoietic Stem cell aging in vivo by a distinct genetic element
- Impaired Stem cell collection by consecutive courses of high-dose mobilizing chemotherapy using cyclophosphamide, etoposide, and G-CSF
- Peripheral Stem cell mobilization and engraftment in patients over age 60
- The chiaroscuro Stem cell : a unified Stem cell theory
- Quiescence regulators for hematopoietic Stem cell
- Hematopoietic Stem cell aging and self-renewal
- Etiology of limbal Stem cell transplantation failure
- DNA repair in Stem cell maintenance and conversion to cancer Stem cells
- Repopulating defect of mismatch repair–deficient hematopoietic Stem cells
- Genetic Uncoupling of the Regulation of Hematopoietic Stem cell Quiescence and Self-Renewal.
- MicroRNA miR-125a controls hematopoietic Stem cell number
- The nuclear receptor tailless induces long-term neural Stem cell expansion and brain tumor initiation
- Marrow aplasia developing 3 years after treatment with busulphan for chronic myeloid leukaemia
- Loss of proliferative capacity in immunohemopoietic Stem cells caused by serial transplantation rather than aging.
- Breaking the cell cycle of HSCs by p57 and friends
- G-CSF in the long-term treatment of cyclic neutropenia and chronic idiopathic neutropenia in adult patients.
- Mechanisms of hematopoietic Stem cell aging
- Failure of ocular surface reconstruction with amniotic membrane transplantation and living-related conjunctival limbal allograft
- Mechanisms that mediate Stem cell self‐renewal and differentiation
- Meeting summary: International Symposium and Workshop on Hematopoietic Stem Cells VI, University of Tübingen, Germany, September 14–16, 2006
- Live and let die: in vivo selection of gene-modified hematopoietic Stem cells via MGMT-mediated chemoprotection
- Clonal escape in Fanconi anemia: new hurdle for gene therapy?
- Aging of Hematopoietic Stem Cells LM Kamminga, R. van Os, A. Ausema, B. Dontje, G. DE HAAN
- Stem cell GENETICS AND GENOMICS: CONCISE REVIEW
- Identification of additional genetic alterations in RUNX1 related leukemias
- Simultaneous Maintenance of Human Cord Blood SCID‐Repopulating Cells and Expansion of Committed Progenitors at Low O2 Concentration (3%)
- How Stem cells age and why this makes us grow old
- Minimal residual disease and discontinuation of therapy in chronic myeloid leukemia: can we aim at a cure?
- Delayed mammary gland development in the p53+/m mouse, a model of accelerated aging
- Long-term interleukin-3 and intensive immunosuppression in the treatment of aplastic anemia.
- cell cycle entry of hematopoietic Stem and progenitor cells controlled by distinct cyclin-dependent kinase inhibitors
- The elements of Stem cell self-renewal: a genetic perspective
- Adult Stem cell maintenance and tissue regeneration in the ageing context: the role for A‐type lamins as intrinsic modulators of ageing in adult Stem cells and their …
- Iron overload and haematopoiesis in MDS: does blood transfusion promote progression to AML?
- Metabolic rate determines haematopoietic Stem cell self-renewal
- Vascular aging: insights from studies on cellular senescence, Stem cell aging, and progeroid syndromes
- Pivotal role for glycogen synthase kinase–3 in hematopoietic Stem cell homeostasis in mice
- Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic Stem cells
- Hematopoietic Support by Endothelium
- Maintenance of quiescent hematopoietic Stem cells in the osteoblastic niche
- Germline Stem Cells: The First Guards of Heredity
- Cancer Stem cells and “Stemness” genes in neuro-oncology
- Granulocyte colony stimulating factor for bone marrow transplantation
- Deciphering the signaling pathways of cancer Stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways.
- Aplastic anaemia: considerations on the pathogenesis
- A human iPSC model of Hutchinson Gilford Progeria reveals vascular smooth muscle and mesenchymal Stem cell defects
- Age-Adjusted Telomere Length Is Not Associated with Variation in Hematological Parameters in Ageing Women
- Ewing sarcoma gene Ews regulates hematopoietic Stem cell senescence
- Notch signaling is required to maintain all neural Stem cell populations–irrespective of spatial or temporal niche
- A conundrum in mammalian hematopoietic Stem cell polarity
- CAMT: new findings and new questions
- cell cycle regulators in Stem cells
- Musashi1: a Stem cell marker no longer in search of a function
- The CDK inhibitors: potential targets for therapeutic Stem cell manipulations?
- Therapeutic targeting of a Stem cell niche
- Lessons learned from the study of JunB: new insights for normal and leukemia Stem cell biology
- The MicroRNA pathway plays a regulatory role in Stem cell division
- Transcriptional activators, repressors, and epigenetic modifiers controlling hematopoietic Stem cell development
- HOXB4 overexpression mediates very rapid Stem cell regeneration and competitive hematopoietic repopulation
- p53 regulates hematopoietic Stem cell quiescence
- Regulation of hematopoietic Stem cells by the steel factor/KIT signaling pathway
- Hematopoietic Stem cells and the genetics of aging
- Stem cells and aging in the hematopoietic syStem
- Wnt signaling in the niche enforces hematopoietic Stem cell quiescence and is necessary to preserve self-renewal in vivo
- The role of the chromatin remodeler Mi-2β in hematopoietic Stem cell self-renewal and multilineage differentiation
- Adult Stem cell therapy beyond haemopoietic Stem cell transplantation? An update
- Calmodulin-dependent Protein Kinase IV Regulates Hematopoietic Stem cell Maintenance*♦
- mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: a roadmap from energy metabolism to Stem cell renewal and …
- Cdc42: a signal coordinator in hematopoietic Stem cell maintenance
- Thioredoxin-interacting protein regulates hematopoietic Stem cell quiescence and mobilization under stress conditions
- Epigenetic regulation of Stem cells in cancer and aging
- IL‐3 and peripheral blood Stem cell harvesting
- Stem cell ageing: does it happen and can we intervene?
- Stem cell factor enhances dendritic cell development
- Effect of Stem cell factor (c-kit ligand), granulocyte-macrophage colony stimulating factor and interleukin 3 on hematopoietic progenitors in human long-term bone …
- Prolonged cell cycle transit is a defining and developmentally conserved hemopoietic Stem cell property
- Stem–cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a
- Stem cell injury and premature senescence
- Haemopoietic Stem cell inhibition: Potential for dose intensification
- JunB protects against myeloid malignancies by limiting hematopoietic Stem cell proliferation and differentiation without affecting self-renewal
- Genistein induces radioprotection by hematopoietic Stem cell quiescence
- Peripheral Stem cell mobilization and engraftment in patients over age 60
- PTEN negatively regulates neural Stem cell self-renewal by modulating G0-G1 cell cycle entry
- Ionizing radiation and aging: rejuvenating an old idea
- The aryl hydrocarbon receptor has a normal function in the regulation of hematopoietic and other Stem/progenitor cell populations
- Effects of prior therapy on the in vitro proliferative potential of Stem cell factor plus filgrastim-mobilized CD34-positive progenitor cells.
- DNA repair defects in Stem cell function and aging
- DNA damage response in adult Stem cells: pathways and consequences
- Telomere dysfunction induces environmental alterations limiting hematopoietic Stem cell function and engraftment
- Survival analysis of conjunctival limbal grafts and amniotic membrane transplantation in eyes with total limbal Stem cell deficiency
- Fanconi anemia Stem cells: going round and round
- Hematopoietic Stem cell self-renewal
- Polycomb group genes: keeping Stem cell activity in balance
- Cyclophosphamide, doxorubicin, vincristine, prednisone dose intensification with granulocyte colony-stimulating factor markedly depletes Stem cell reserve for …
- Dedifferentiation rescues senescence of progeria cells but only while pluripotent
- Notch signaling in the regulation of Stem cell self-renewal and differentiation
- Neural tumor-initiating cells have distinct telomere maintenance and can be safely targeted for telomerase inhibition
- Decline in self-renewal factors contributes to aging of the Stem cell niche in the Drosophila testis
- YY1 PcG function as a potential cancer therapeutic target
- Stem cell proliferation and quiescence—two sides of the same coin
- Awakening dormant haematopoietic Stem cells
- c-Myc controls the balance between hematopoietic Stem cell self-renewal and differentiation
- Multi-genetic events collaboratively contribute to Pten-null leukaemia Stem–cell formation
- Regulation of bone marrow-derived vascular progenitor cell mobilization and maintenance
- Latent hematopoietic Stem cell toxicity associated with protracted drug administration
- Wnt-inhibitory factor 1 dysregulation of the bone marrow niche exhausts hematopoietic Stem cells
- Hematopoietic Stem cell development, aging and functional failure
- Bone marrow-derived cells: the influence of aging and cellular senescence
- Effects of dietary restriction on hematopoietic Stem–cell aging are genetically regulated
- p16INK4a and Stem cell Ageing: A Telomere-Independent Process?
- FILAMENTARY KERATITIS-A REVIEW OF ETIOP A REVIEW OF ETIOPATHOGENESIS AND MANAGEMENT THOGENESIS AND MANAGEMENT
- Limiting factors in murine hematopoietic Stem cell assays
- Pbx1 regulates self-renewal of long-term hematopoietic Stem cells by maintaining their quiescence
- Telomere dysfunction and Stem cell ageing
- The daunting task of modeling response to imatinib therapy in patients with chronic myelogenous leukemia
- Telomeres and telomerase in cancer Stem cells
- Pten deletion in adult neural Stem/progenitor cells enhances constitutive neurogenesis
- Endothelial progenitor cell mobilization after percutaneous coronary intervention
- The transcription factor EGR1 controls both the proliferation and localization of hematopoietic Stem cells
- Tissue engineering of the cornea
- Intrinsic control of Stem cell fate
- Effects of Prior Therapy on the in Vitro Proliferative Potential of Stem cell Factor Plus Filgrastim-mobilized CD34-positive Progenitor Cells1
- Hematopoiesis: an evolving paradigm for Stem cell biology
- The pessimist’s and optimist’s views of adult neurogenesis
- Mechanisms controlling hematopoietic Stem cell functions during normal hematopoiesis and hematological malignancies
- Mouse Model: Telomeres and Telomerase in Stem cell and Cancer
- Stem cell model of hematopoiesis
- Goralatide (AcSDKP), a negative growth regulator, protects the Stem cell compartment during chemotherapy, enhancing the myelopoietic response to GM‐CSF
- A risk-benefit assessment of epoetin in the management of anaemia associated with cancer
- Compartmentalized organization: a common and required feature of Stem cell niches?
- Tuning mTORC1 activity for balanced self-renewal and differentiation
- Gene therapy approaches for Stem cell protection
- Loss of the Rho GTPase activating protein p190-B enhances hematopoietic Stem cell engraftment potential
- Hematopoietic Stem cells and aging
- HEMATOPOIETIC Stem cell TRANSFER: LBNT1 VIRUS VECTORS
- The stromal cells’ guide to the Stem cell universe
- Regulation of murine hematopoietic Stem cell quiescence by Dmtf1
- Signaling through BMPR-IA regulates quiescence and long-term activity of neural Stem cells in the adult hippocampus
- Tumor suppressor dosage regulates Stem cell dynamics during aging
- Mesenchymal Stem cell transplantation for tissue repair
- EZH2 is a mediator of EWS/FLI1 driven tumor growth and metastasis blocking endothelial and neuro-ectodermal differentiation
- Telomeres in hematopoietic Stem cells
- Regulation of Stem cell pluripotency and differentiation involves a mutual regulatory circuit of the NANOG, OCT4, and SOX2 pluripotency transcription factors with …
- The roles of EZH2 in cell lineage commitment
- Hematopoietic Stem cell aging: wrinkles in Stem cell potential
- Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition
- Genomic instability in induced Stem cells
- Inactivating mutations of the histone methyltransferase gene EZH2 in myeloid disorders
- Human skin Stem cells and the ageing process
- Polycomb repressive complex 2 is dispensable for maintenance of embryonic Stem cell pluripotency
- Ontogenic growth of the haemopoietic Stem cell pool in humans
- Inside Blood: a roadmap to the best and brightest
- A low level of reactive oxygen species selects for primitive hematopoietic Stem cells that may reside in the low-oxygenic niche
- Stem cells, DNA damage, ageing and cancer
- Hematopoietic Stem cell quiescence is maintained by compound contributions of the retinoblastoma gene family
- Polycomb repressive complex 2 (PRC2) restricts hematopoietic Stem cell activity
- Maintenance of adult Stem cells: Role of the Stem cell niche
- The orphan nuclear receptor Nurr1 restricts the proliferation of haematopoietic Stem cells
- Metabolic regulation of hematopoietic Stem cells in the hypoxic niche
- Stem cell defects in ATM-deficient undifferentiated spermatogonia through DNA damage-induced cell -cycle arrest
- Ci er chun he duan li yu qing jiang yu Oryzias melastigma shou ming de xiang guan xing yan jiu
- Clonal diversity of the Stem cell compartment
- Rac1 is required for epithelial Stem cell function during dermal and oral mucosal wound healing but not for tissue homeostasis in mice
- Manifestations and mechanisms of Stem cell aging
- 6 2 6 Editorials The Journal of Pediatrics November 1996
- Age-specific bone tumour incidence rates are governed
- Autologous limbal transplantation in unilateral chemical burns
- Tracking down the Stem cells of the intestine: strategies to identify adult Stem cells
- Gfi-1: another piece in the HSC puzzle
- Polycomb group proteins: multi-faceted regulators of somatic Stem cells and cancer
- Toward ‘SMART’Stem cells
- Expression of Stem cell markers on mononuclear cells derived from heparinized cadaveric organ donors before and after disconnection from the respirator
- Handbook on Immunosenescence: Basic Understanding and Clinical Applications
- Understanding cellular networks to improve hematopoietic Stem cell expansion cultures
- Regulation of Self-Renewing Divisions in Normal and Leukaemia Stem Cells
- Using naturally occurring tumours in dogs and cats to study telomerase and cancer Stem cell biology
- Impaired PBPC collection in patients with myeloma after high-dose melphalan
- Human Stem cell engraftment in sheep
- Transplantation of hematopoietic Stem cells from the peripheral blood
- The molecular specificity of action of the tetrapeptide acetyl‐n‐ser‐asp‐lys‐pro (AcSDKP) in the control of hematopoietic Stem cell proliferation
- Altered mammary gland development in the p53+/m mouse, a model of accelerated aging
- Effect of chronic cytokine therapy on clonal dynamics in nonhuman primates
- Plzf regulates germline progenitor self-renewal by opposing mTORC1
- Telomere attrition occurs during ex vivo expansion of human dental pulp Stem cells
- Rapamycin and quasi-programmed aging: Four years later
- At the Stem of youth and health
- Heterozygous kit mutants with little or no apparent anemia exhibit large defects in overall hematopoietic Stem cell function
- Hematopoietic Stem cells reversibly switch from dormancy to self-renewal during homeostasis and repair
- cell cycle regulators in adult Stem cells
- Estimating dormant and active hematopoietic Stem cell kinetics through extensive modeling of bromodeoxyuridine label-retaining cell dynamics
- The p53–p66shc–manganese superoxide dismutase (MnSOD) network: a mitochondrial intrigue to generate reactive oxygen species
- Hemopoietic function after use of IL-1 with chemotherapy or irradiation
- A Stem cell fusion model of carcinogenesis.
- Genome-wide mapping of Polycomb target genes unravels their roles in cell fate transitions
- Regulation of murine hematopoietic Stem cell quiescence by cyclin D binding myb-like transcription factor-1, Dmtf1
- Signaling pathways in self-renewing hematopoietic and leukemic Stem cells: do all Stem cells need a niche?
- Bone marrow Stem cell protection from chemotherapy by low–molecular-weight compounds
- Unraveling the complex regulation of Stem cells: implications for aging and cancer
- CD34 promotes satellite cell motility and entry into proliferation to facilitate efficient skeletal muscle regeneration
- 2010 International Forum on Stem Cells (November 11–13; Tianjin, China)
- The autophagy protein Atg7 is essential for hematopoietic Stem cell maintenance
- p53-mediated hematopoietic Stem and progenitor cell competition
- Pharmacological inhibition of EGFR signaling enhances G-CSF–induced hematopoietic Stem cell mobilization
- Sustained activation of mTOR pathway in embryonic neural Stem cells leads to development of tuberous sclerosis complex-associated lesions
- Runx1 loss minimally impacts long-term hematopoietic Stem cells
- Sirolimus and tacrolimus binding proteins: double-edged swords for GVHD prophylaxis
- In vivo selection using a cell -growth switch
- Mesenchymal Stem cells inhibit proliferation and apoptosis of tumor cells: impact on in vivo tumor growth
- Telomeres and Telomerase
- Tracking adult Stem cells
- The Wnt antagonist Dickkopf-1 mobilizes vasculogenic progenitor cells via activation of the bone marrow endosteal Stem cell niche
- Identification of tumor-initiating cells in a p53-null mouse model of breast cancer
- Telomere biology in hematopoiesis and Stem cell transplantation
- Evaluation and eligibility of HLA‐identical sibling donors for Stem cell /bone marrow donation
- Ontogeny-related changes in proliferative potential of human hematopoietic cells.
- Establishment of an aging model of Sca-1+ hematopoietic Stem cell and studies on its relative biological mechanisms
- Modern genome-wide genetic approaches to reveal intrinsic properties of Stem cells
- Hematopoietic Stem cell Aging and Fate Decision
- Epithelial Stem cells: An epigenetic and wnt‐centric perspective
- Marked telomere fluctuation of leukocytes during graft-versus-host disease in allogeneic Stem cell transplantation
- Macrophage Inflammatory Protein-1α and Stem cell Inhibition
- Hematopoietic Stem cell Aging and Fate Decision
- Cytokine-mediated expansion does not deplete cord blood cells with Stem cell characteristics
- Ways of minimising hematopoietic damage induced by radiation and cytostatic drugs—the possible role of inhibitors
- Hematopoietic Stem cell emergence in embryonic life: developmental hematology revisited
- Cancer therapy-induced residual bone marrow injury: mechanisms of induction and implication for therapy
- Hayflick’s hypothesis: an approach to in vivo testing
- Expansion of LTC-ICs and Maintenance of p21 and BCL-2 Expression in Cord Blood CD34+/CD38− Early Progenitors Cultured over Human MSCs as a Feeder …
- Haemoprotection against cytostatic drugs by Stem cell inhibition
- All-trans retinoic acid induces proliferation of an irradiated Stem cell supporting stromal cell line AFT024
- Progress in the development of syStems for in vitro expansion of human hematopoietic Stem cells
- Homeostasis of telomere length rather than telomere shortening after allogeneic peripheral blood Stem cell transplantation
- From tissue turnover to the cell of origin for pancreatic cancer
- Hematopoietic Stem cells: generation and self-renewal
- Improved outcome following allogeneic Stem cell transplantation in chronic myeloid leukemia is associated with higher expression of BMI-1 and immune …
- Hematopoietic progenitor/Stem cells immortalized byLhx2 generate functional hematopoietic cells in vivo
- Hematopoiesis from human embryonic Stem cells
- Current concepts in the pathophysiology and treatment of aplastic anemia
- Do we have to kill the last CML cell ?
- High‐dose therapy with peripheral blood Stem cell transplantation results in a significant reduction of the haemopoietic progenitor cell compartment
- cell death by sugar: Bittersweet TOR
- Fanconi anaemia: new strategies
- Aplastic anemia: pathogenesis and treatment
- Epigenetic modifications of Stem cells: a paradigm for the control of cardiac progenitor cells
- Splenic primitive hematopoietic Stem cell (PHSC) activity is enhanced by steel factor because of PHSC proliferation
- Stem cell factor augments tumor necrosis factor-granulocyte-macrophage colony-stimulating factor-mediated dendritic cell hematopoiesis
- Rapamycin and other longevity‐promoting compounds enhance the generation of mouse induced pluripotent Stem cells
- The microRNA cluster miR-106b~ 25 regulates adult neural Stem/progenitor cell proliferation and neuronal differentiation
- Stems cells and the pathways to aging and cancer
- The transcriptional coactivator Cbp regulates self-renewal and differentiation in adult hematopoietic Stem cells
- Discontinuation of imatinib in patients with chronic myeloid leukaemia who have maintained complete molecular remission for at least 2 years: the prospective …
- Polycomb silencers control cell fate, development and cancer
- In vivo radioprotective effect of AcSDKP on canine myelopoiesis
- Hypoxia-inducible factors and marrow stromal function
- Management of Acute Leukemia
- Polycomb group proteins in hematopoietic Stem cell aging and malignancies
- Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations
- Posttransplant hematopoiesis in patients undergoing sibling allogeneic Stem cell transplantation reflects that of their respective donors although with a lower functional …
- Hematopoietic Stem cells are not the direct target of spontaneous leukemic transformation in p18INK4C-null reconstituted mice
- Stonewalling Drosophila Stem cell differentiation by epigenetic controls
- Hematopoietic Stem cell expansion
- The E3 ligase Itch is a negative regulator of the homeostasis and function of hematopoietic Stem cells
- The critical role of agrin in the hematopoietic Stem cell niche
- Fancd2 −/− mice have hematopoietic defects that can be partially corrected by resveratrol
- cell cycle and developmental control of hematopoiesis by Runx1
- Genotoxic stress abrogates renewal of melanocyte Stem cells by triggering their differentiation
- Gone with the Wnt/Notch: Stem cells in laminopathies, progeria, and aging
- Differentiation of neural Stem cells into oligodendrocytes: involvement of the polycomb group protein Ezh2
- Melanocyte Stem cells
- Hematopoietic Stem cells and the aging hematopoietic syStem
- In vivo T-cell dynamics during immune reconstitution after hematopoietic Stem cell gene therapy in adenosine deaminase severe combined immune deficiency
- Hemopoietic Function After Use of IL-1 with
- Genetic Regulation of Hematopoietic Stem cell Aging
- Wnt Signaling in the Niche Enforces Hematopoietic Stem cell Quiescence and Is Necessary to Preserve Self-Renewal…
- Pathophysiologic mechanisms in acquired aplastic anemia
- EWS-FLI-1 expression triggers a Ewing’s sarcoma initiation program in primary human mesenchymal Stem cells
- Shifting senescence into quiescence by turning up p53
- The Wnt receptor, Lrp5, is expressed by mouse mammary Stem cells and is required to maintain the basal lineage
- Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic Stem cells
- Clonal haemopoiesis may occur after conventional chemotherapy and is associated with accelerated telomere shortening and defects in the NQO1 pathway; possible …
- Cellular and Molecular Crossroads of Cancer and Aging
- Chaotic dynamic stabilities and instabilities of hematopoietic Stem cell growth plasticity
- Have We Reached the Point for In Vivo Rejuvenation?
- Developmental plasticity of Stem cells and diseases
- Musashi1 modulates mammary progenitor cell expansion through proliferin-mediated activation of the Wnt and Notch pathways
- Impact papers on aging in 2009
- Principles of hematopoietic Stem cell biology
- The t (6; 9) associated DEK/CAN fusion protein targets a population of long-term repopulating hematopoietic Stem cells for leukemogenic transformation
- GATA2 finds its macrophage niche
- Donor age and cell passage affects differentiation potential of murine bone marrow-derived Stem cells
- Hematopoietic Stem cells
- Reduced Proliferative Capacity of Hematopoietic Stem Cells Deficient in Hoxb3 and Hoxb4
- Roles of PPAR and p21WAF1/CIP1 in monocyte/macrophage differentiation: are circulating monocytes able to proliferate?
- The aryl hydrocarbon receptor: regulation of hematopoiesis and involvement in the progression of blood diseases
- Bigger is better: maternal and neonatal predictors of hematopoietic potential of umbilical cord blood units
- Transcription factor Gfi1 regulates self‐renewal and engraftment of hematopoietic Stem cells
- Wnt/β-catenin signaling induces the aging of mesenchymal Stem cells through the DNA damage response and the p53/p21 pathway
- cell divisions and mammalian aging: integrative biology insights from genes that regulate longevity
- Preservation of Hemopoietic Stem Cells
- Stable differentiation and clonality of murine long-term hematopoiesis after extended reduced-intensity selection for MGMT P140K transgene expression
- 10 Epigenetics in Cancer Stem cell Development
- The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells
- Blood disorders in the elderly
- Normal Stem cells and cancer Stem cells: similar and different
- Attributes of adult Stem cells
- Risk-adapted procedures for HSCT from alternative donor in children with severe aplastic anaemia
- Stem cell niches and other factors that influence the sensitivity of bone marrow to radiation-induced bone cancer and leukaemia in children and adults
- E47 controls the developmental integrity and cell cycle quiescence of multipotential hematopoietic progenitors
- Haploinsufficiency of SNEV causes defects of hematopoietic Stem cells functions
- The Future of Hematopoietic Growth Factors
- Telomere length in paroxysmal nocturnal hemoglobinuria correlates with clone size
- Genetic marking as an approach to studying in vivo hematopoiesis: progress in the non-human primate model
- Standardization of hematopoietic Stem cell assays: a summary of a workshop and working group meeting sponsored by the National Heart, Lung, and Blood Institute …
- Identification of Stem cell transcriptional programs normally expressed in embryonic and neural Stem cells in alloreactive CD8+ T cells mediating graft-versus …
- Inhibitors of haemopoiesis and their potential clinical relevance
- Aging Stem cells, latexin and longevity
- Sequential sectoral conjunctival epitheliectomy (SSCE)
- Activation of developmental signaling pathways in hematopoietic Stem cell regeneration
- Somatic and germline genetics at the JAK2 locus
- Kinetics of normal hematopoietic Stem and progenitor cells in a Notch1-induced leukemia model
- Rac1 Is Required for Epithelial Stem cell Function during Dermal and Oral
- MicroRNA profiling reveals age-dependent differential expression of nuclear factor κB and mitogen-activated protein kinase in adipose and bone marrow …
- Epigenetic regulation of satellite cell activation during muscle regeneration
- Antithymocyte globulin and cyclosporine for severe aplastic anemia: association between hematologic response and long-term outcome
- Essential biology of Stem cell transplantation
- Regulatory circuitries coordinated by transcription factors and microRNAs at the cornerstone of hematopoietic Stem cell self-renewal and differentiation
- Repopulating Activity of Ex Vivo‐Expanded Murine Hematopoietic Stem Cells Resides in the CD48−c‐Kit+Sca‐1+Lineage Marker− cell Population
- Retroviral expression of arginine decarboxylase attenuates oxidative burden in mouse cortical neural Stem cells
- A reappraisal by quantitative flow cytometry analysis of PTEN expression in acute leukemia
- Searching for adult Stem cells in the intestine
- Aging, exercise, and endothelial progenitor cell clonogenic and migratory capacity in men
- The tumor suppressor p53 regulates polarity of self-renewing divisions in mammary Stem cells
- Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic Stem cells in glioblastoma
- Growth factors and the molecular control of haematopoiesis
- BMI1 confers radioresistance to normal and cancerous neural Stem cells through recruitment of the DNA damage response machinery
- MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic Stem cells
- Chromatin modulation by oncogenic transcription factors: new complexity, new therapeutic targets
- Hemopoietic alterations of cancer
- Clinical challenges and cord blood transplantation: are we asking the right questions?
- Life and death in hematopoietic Stem cells
- The hemoregulatory peptide pEEDCK may inhibit Stem cell proliferation via hydropathic binding to antisense sequence motifs in interleukin-11 and other growth …
- Elucidating the role of metabolic factors in hematopoietic Stem cell maintenance
- Dysfunctional endothelial progenitor cells in chronic kidney disease
- Cancer Stem cells and aneuploid populations within developing tumors are the major determinants of tumor dormancy
- Telomere length and proliferation potential of hematopoietic Stem cells
- Age, caste, and behavior determine the replicative activity of intestinal Stem cells in honeybees (Apis mellifera L.)
- Replicative potential and telomere length in human skeletal muscle: implications for satellite cell -mediated gene therapy
- Aging and disease as modifiers of efficacy of cell therapy
- Telomerase inhibition targets clonogenic multiple myeloma cells through telomere length-dependent and independent mechanisms
- A Runx1 Intronic Enhancer Marks Hemogenic Endothelial Cells and Hematopoietic Stem Cells
- PROSPECT
- Differentiated cells are more efficient than adult Stem cells for cloning by somatic cell nuclear transfer
- Leukemia Stem Cells
- Ezh2, the histone methyltransferase of PRC2, regulates the balance between self-renewal and differentiation in the cerebral cortex
- Growth Factors Promote High-Dose Chemotherapy
- cell kinetics of CD34‐positive hematopoietic cells following chemotherapy plus colony‐stimulating factors in advanced breast cancer
- Aplastic Anemia & MDS International Foundation (AA&MDSIF): Bone marrow failure disease scientific symposium 2010
- The aryl hydrocarbon receptor has an important role in the regulation of hematopoiesis: implications for benzene-induced hematopoietic toxicity
- Accelerated telomere shortening precedes development of therapy-related myelodysplasia or acute myelogenous leukemia after autologous transplantation …
- Intratibial injection of an anti-doxorubicin monoclonal antibody prevents drug-induced myelotoxicity in mice
- Investigating The Role Of Runx1 In Hair Follicle Stem cell Development And Homeostasis
- cell cycle, CDKs and cancer: a changing paradigm
- Protective effects of BB-10010 treatment on chemotherapy-induced neutropenia in mice
- The Paton Lecture: Ocular Surface Transplantation 10 Years’ Experience
- Idiopathic Aplastic Anemia
- Mast cell growth factor enhances multilineage hematopoietic recovery in vivo following radiation-induced aplasia
- Growth factors and hematopoietic recovery
- 7 Growth inhibitors in haemopoiesis and leukaemogenesis
- Simultaneous knockdown of p18INK4C, p27Kip1 and MAD1 via RNA interference results in the expansion of long-term culture-initiating cells of murine bone marrow …
- Granulocyte colony–stimulating factor administration: adverse events
- Stem cells and cancer: evidence for bone marrow Stem cells in epithelial cancers
- Shp-2 heterozygous hematopoietic Stem cells have deficient repopulating ability due to diminished self-renewal
- Leukemia Stem Cells, A Pioneering Paradigmatic Model
- Regulation of reactive oxygen species and genomic stability in hematopoietic Stem cells
- mTOR: from growth signal integration to cancer, diabetes and ageing
- Bone marrow failure syndromes
- Dyskerin, telomerase and the DNA damage response
- The road to commitment: lineage restriction events in hematopoiesis
- Skeletal muscle Stem cells: effects of aging and metabolism on muscle regenerative function
- 22 THE NORMAL BONE MARROW AND MANAGEMENT OF TOXIN-INDUCED Stem cell FAILURE
- Targeting leukemia Stem cells: The new goal of therapy in adult acute myeloid leukemia
- Bmi1 is a MYCN target gene that regulates tumorigenesis through repression of KIF1B β and TSLC1 in neuroblastoma
- cell cycle regulation in hematopoietic Stem cells
- HLA-matched living-related conjunctival limbal allograft for bilateral ocular surface disorders: long-term results
- EZH2 and BMI1 inversely correlate with prognosis and TP53 mutation in breast cancer
- Phenotypic and Functional Changes in Cord Blood Stem cell Progeny after Cytokine Activation
- Lentiviral gene transfer regenerates hematopoietic Stem cells in a mouse model for Mpl-deficient aplastic anemia
- In vitro expansion of CD34+ cells mobilized with chemotherapy and G-CSF
- Conditional induction of the telomerase reverse transcriptase protein and effects on Stem cell division in vivo
- Replicative senescence and cell immortality: the role of telomeres and telomerase
- Histone deacetylase inhibitors in the treatment of muscular dystrophies: epigenetic drugs for genetic diseases
- Same‐day determination of chimaeric status in the immediate period following allogeneic bone marrow transplantation
- Deletion of Puma protects hematopoietic Stem cells and confers long-term survival in response to high-dose γ-irradiation
- Epigenetic therapy
- The emerging role of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in normal myelopoiesis and leukemogenesis
- Stem cells and cancer in the aerodigestive tract
- Histone deacetylase inhibitors deplete enhancer of zeste 2 and associated polycomb repressive complex 2 proteins in human acute leukemia cells
- Leukemia Stem cells and new strategies to overcome resistance to therapy
- PUMA kills Stem cells to stall cancer?
- Polycomb-group oncogenes EZH2, BMI1, and RING1 are overexpressed in prostate cancer with adverse pathologic and clinical features
- Growth factor changes in ex vivo expansion of human limbal epithelial cells on human amniotic membrane
- cell cycle control and check points in hematopoietic Stem cells
- Ovarian cancer plasticity and epigenomics in the acquisition of a Stem-like phenotype
- Practical Use of Hematopoietic Growth Factors in HIV Infection
- Novel Treatment Options
- Replicative senescence of mesenchymal Stem cells causes DNA-methylation changes which correlate with repressive histone marks
- Genetic Regulation of Hematopoietic Stem cell Numbers in Mice
- The biology of cancer Stem cells
- Self-renewal of primitive hematopoietic cells: a focus on asymmetric cell division
- The Tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro (Goralatide) Protects From
- 2006 Kent Award Lecture: Is cell death and replacement a factor in aging?
- Transcriptional and epigenetic regulation of B cell development
- Cigarette Smoke Triggers Code Red: p21CIP1/WAF1/SDI1 Switches on Danger Responses in the Lung
- cell Cycle-Related Changes in Repopulating Capacity of Human Mobilized Peripheral Blood CD34+ Cells in Non-Obese Diabetic/Severe Combined Immune …
- degree of Doctor of Philosophy (Ph. D.)
- Research on Hutchinson-Gilford progeria syndrome
- TOR-driven aging: speeding car without brakes
- Prolonged cell Cycle Transit Is a Defining
- The BALANCE Study: clinical benefit and long-term outcome after intracoronary autologous bone marrow cell transplantation in patients with acute myocardial …
- Mobilization of Peripheral Blood Stem Cells from Normal Donors
- Angiopoietin1 contributes to the maintenance of cell quiescence in EVI1high leukemia cells
- Mobilization and transplantation of peripheral blood Stem cells
- The role of telomere biology in bone marrow failure and other disorders
- Telomere biology of human hematopoietic Stem cells
- Haemopoietic defect and decreased expansion potential of bone marrow autografts from patients with acute myeloid leukaemia in first remission
- Wnt signaling regulates hepatic metabolism
- Epigenetic dysregulation in cancer
- The DNA-damage response in human biology and disease
- Pharmacologic Induction of CD8+ T cell Memory: Better Living Through Chemistry
- Mice severely deficient in growth hormone have normal hematopoiesis
- Erythropoiesis in murine long‐term bone‐marrow cell cultures: Dependence on erythropoietin and endogenous production of an erythropoietic stimulating activity
- Mobilization of Pheripheral Blood Stem Cells from Normal Donors
- Empowering adult Stem cells for myocardial regeneration
- Short-term injection of antiapoptotic cytokine combinations soon after lethal γ-irradiation promotes survival
- Overview of hemopoiesis and hemopoietic reconstruction
- Factors that may impact on immunosenescence: an appraisal
- Dietary Restriction: A Model SyStem Probing the cell Fate Decision Between Cancer and Senescence
- Lineage-specific hematopoietic growth factors
- Protection from arabinofuranosylcytosine and n-mustard-induced myelotoxicity using hemoregulatory peptide pGlu-Glu-Asp-Cys-Lys monomer and dimer
- Modeling notch signaling in normal and neoplastic hematopoiesis: global gene expression profiling in response to activated notch expression
- Dependency on the polycomb gene Ezh2 distinguishes fetal from adult hematopoietic Stem cells
- Functional analysis of the homeobox gene HOXB4 in primitive hematopoietic cells
- Changing concepts in the management of severe ocular surface disease over twenty-five years
- TGFβ signaling in male germ cells regulates gonocyte quiescence and fertility in mice
- Short telomeres resulting from heritable mutations in the telomerase reverse transcriptase gene predispose for a variety of malignancies
- Recurrence of aplastic anemia following cyclophosphamide and syngeneic bone marrow transplantation: evidence for two mechanisms of graft failure
- In Vitro Modifications Induced by Granulocyte-Macrophage Colony-Stimulating Factor in Human Long-Term Bone Marrow Cultures
- Mechanisms of Wnt-and Notch-mediated Stem cell self-renewal
- Cancer Stem cells: the emerging challenge of drug targeting
- An RbAp48-like gene regulates adult Stem cells in planarians
- GM-CSF multiple course priming and long-term administration in newly diagnosed acute myeloid leukemia: Comparison of three different GM-CSF routes and …
- Genome-wide promoter DNA methylation dynamics of human hematopoietic progenitor cells during differentiation and aging
- Premeiotic germ cell defect in seminiferous tubules of Atm-null testis
- cell cycle regulators and hematopoiesis
- Quantitative analysis of mixed chimerism following allogeneic bone marrow transplantation using telomere flow-FISH
- Senescence and apoptosis in yeast mother cell -specific aging and in higher cells: a short review
- Bid is a positive regulator for donor-derived lymphoid cell regeneration in γ-irradiated recipients
- Peripheral blood progenitor cells versus bone marrow
- Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
- Transplante alogênico inter vivo de limbo conjuntival com pareamento HLA em doenças bilaterais da superfície ocular: resultados em longo prazo
- Activation of adenosine A3 receptors supports hematopoiesis-stimulating effects of granulocyte colony-stimulating factor in sublethally irradiated mice
- The biology and clinical uses of blood Stem cells
- The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic Stem cells and mature lineage progenitors by protecting from genotoxic stress
- Autologous and allogeneic transplantation with peripheral blood CD34+ cells: a pediatric experience
- Craniofacial Reconstruction and Aging of Human Mesenchymal Stem Cells
- Principles of hematotoxicology: laboratory assessment and interpretation of data
- Telomere dynamics in hematopoietic Stem cells
- Characterisation of the leukemic Stem cell in a murine model of CALM/AF10 positive myeloid leukemia
- cell aging in relation to stress arousal and cardiovascular disease risk factors
- Cytokine receptors, growth factors and cell cycle in human bone marrow and peripheral blood hematopoietic progenitors
- A low level of reactive oxygen species selects for primitive hematopoietic
- RUNX1 regulates the CD34 gene in haematopoietic Stem cells by mediating interactions with a distal regulatory element
- Norc sIGNALLING Is REQUIRED FOR
- Additive effect of TAp63 deficiency on the adrenocortical dysplasia (acd) phenotype
- Protection and selection for gene therapy in the hematopoietic syStem
- Genetic variation in healthy oldest-old
- Haemopoietic Stem cells: their heterogeneity and regulation
- Age-related decline in immunity: implications for vaccine responsiveness
- Promiscuous and lineage-specific roles of cell cycle regulators in haematopoiesis
- Bone marrow CD34+ cells expanded on human brain endothelial cells reconstitute lethally irradiated baboons in a variable manner
- A Runx1-Smad6 rheostat controls Runx1 activity during embryonic hematopoiesis
- Myelodysplastic syndrome and aplastic anemia: distinct entities or diseases linked by a common pathophysiology?
- Mechanisms of Yin Yang 1 in oncogenesis: the importance of indirect effects
- Mutations of mitochondrial DNA–cause or consequence of the ageing process?
- Efficacy of up-front 5-fluorouracil–epidoxorubicin–cyclophosphamide (FEC) chemotherapy with an increased dose of epidoxorubicin in high-risk breast cancer …
- Notch1 modulates timing of G1-S progression by inducing SKP2 transcription and p27Kip1 degradation
- Adult-onset, short-term dietary restriction reduces cell senescence in mice
- The emerging roles of forkhead box (Fox) proteins in cancer
- Overexpression of Enhancer of zeste homolog 2 with trimethylation of lysine 27 on histone H3 in adult T-cell leukemia/lymphoma as a target for epigenetic …
- The molecular mechanisms that control thrombopoiesis
- Hematopoietic Effect of Fractions from the Enzyme-Digested colla corii asini on Mice with 5-Fluorouracil Induced Anemia
- The Wnt Receptor
- Stem cells for skeletal muscle repair
- Three-month therapeutic effect of bone marrow mesenchymal Stem cells transplantation on the treatment of X-linked muscular distrophy mice
- The evolution and classification of ocular surface transplantation
- Hematopoietic Stem Cells and Somatic Stem Cells
- Prospective isolation and molecular characterization of hematopoietic Stem cells with durable self-renewal potential
- Pseudo-DNA damage response in senescent cells
- Interferon-γ and tumor necrosis factor-α differentially affect cytokine expression and migration properties of mesenchymal Stem cells
- CDKs and CKIs: molecular targets for tissue remodelling
- Clonality analysis of childhood ALL in remission: no evidence of clonal hematopoiesis
- Aryl hydrocarbon receptor-null allele mice have hematopoietic Stem/progenitor cells with abnormal characteristics and functions
- Biology of bone marrow-derived endothelial cell precursors
- Telomere dysfunction triggers developmentally regulated germ cell apoptosis
- Paroxysmal nocturnal hemoglobinuria: pathophysiology, natural history and treatment options in the era of biological agents
- Issues in the clinical development of recombinant methionyl human granulocyte colony-stimulating factor: A review
- Telomeres and telomerase regulation
- Increased longevity of hematopoiesis in continuous bone marrow cultures derived from NOS1 (nNOS, mtNOS) homozygous recombinant negative mice correlates with …
- Macrophage Inflammatory Protein 1α Attenuates the Toxic Effects of Temozolomide in Human Bone Marrow Granulocyte-Macrophage Colony-forming Cells
- Chemoprotection and selection by chemotherapy of multidrug resistance-associated protein-1 (MRP1) transduced cells
- Radio-and chemoprotection of bone marrow cells by opposite cell cycle-acting cytokines
- Lineage-specific differences in telomere length after bone marrow transplantation
- Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia …
- DNA damage and cellular differentiation: more questions than responses
- Granulocyte-stimulating factor and severe aplastic anemia: a survey by the European Group for Blood and Marrow Transplantation (EBMT)
- DNMT3b’s Role in Hematopoietic Stem Cells
- Opposing roles of polycomb repressive complexes in hematopoietic Stem and progenitor cells
- Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal
- Macrophage Inflammatory Protein 1 Attenuates the Toxic Effects of Temozolomide in Human Bone Marrow Granulocyte-Macrophage Colony-forming Cells1
- Your use of the JSTOR archive indicates your acceptance of JSTOR’s Terms and Conditions of Use, available at
- Accelerated wound healing by mTOR activation in genetically defined mouse models
- Unexpected Proatherogenic Properties of p21
- Autophagy and aging
- Cotransplantation of third-party mesenchymal stromal cells can alleviate single-donor predominance and increase engraftment from double cord transplantation
- The ageing epigenome: damaged beyond repair?
- Focal adhesion kinase is required for intestinal regeneration and tumorigenesis downstream of Wnt/c-Myc signaling
- WNT signaling in adult cardiac hypertrophy and remodeling: lessons learned from cardiac development
- cell death in the nervous syStem
- In vivo haemoprotective activity of tetrapeptide AcSDKP combined with granulocyte‐colony stimulating factor following sublethal irradiation
- Ndy1/KDM2B immortalizes mouse embryonic fibroblasts by repressing the Ink4a/Arf locus
- A continuum model for tumour suppression
- Steel factor coordinately regulates the molecular signature and biologic function of hematopoietic Stem cells
- Myelopoietic response in tumour-bearing mice by an aggregated polymer isolated from Aspergillus oryzae
- Overexpression of the MnSOD transgene product protects cryopreserved bone marrow hematopoietic progenitor cells from ionizing radiation
- Stimulatory effects of polar glycopeptidolipids of Mycobacterium chelonae on murine haematopoietic Stem cells and megakaryocyte progenitors
- EWS-FLI-1 Expression Triggers a Ewing’s Sarcoma Initiation Program in Primary Human Mesenchymal Stem Cells
- Microsatellite instability is not an uncommon finding in adult de novo acute myeloid leukemia
- Macrophages in injured skeletal muscle: a perpetuum mobile causing and limiting fibrosis, prompting or restricting resolution and regeneration
- Aging of the Hematopoietic SyStem
- Specific roles of Target of rapamycin in the control of Stem cells and their progeny in the Drosophila ovary
- cell senescence: the future of ageing?
- Circadian‐based effects of AcSDKP, with or without rhG–CSF on hematologic toxicity of chemotherapy in mice
- Aging-associated decline in innate immunity and therapeutic strategies to counteract it
- Characterization of CD62L as a marker of hematopoietic differentiation in adult mice
- Canonical and non-canonical Wnt signaling in hematopoiesis and lymphocyte
- The Role of the DNA Mismatch Repair Pathway in Adult Stem Cells In Vivo
- Retroviral gene therapy in hematopoietic diseases
- Hematopoietic Stem cells: molecular diversification and developmental interrelationships
- Abnormalities of axon growth in human olfactory mucosa
- SDF-1 involvement in endothelial phenotype and ischemia-induced recruitment of bone marrow progenitor cells
- Unexpected proatherogenic properties of p21: beyond cell cycle control?
- Genetic modification of ex-vivo expanded Stem cells for clinical application
- Wnt/β-catenin signaling in normal and cancer Stem cells
- How transcription factors program chromatin—lessons from studies of the regulation of myeloid-specific genes
- Intra-articular injections in capsulitis
- Targeting malignant B cell self-renewal and differentiation
- Graft failure following allogeneic blood and marrow transplant: evidence-based nursing case study review
- Gene transfer of cytidine deaminase protects myelopoiesis from cytidine analogs in an in vivo murine transplant model
- Molecular damage in cancer: an argument for mTOR-driven aging
- Intercellular feedback in hematopoiesis
- Acute myeloblastic leukemia and recombinant granulocyte colony stimulating factor.
- Retrospective Review of Odontogenic Infections at a Tertiary Medical Center: Clinical Correlations Based on Culture and Sensitivity Data
- As a matter of fat: new perspectives on the understanding of age-related bone loss
- Suppression of tumor suppressors in prostate cancer: the emergence of a novel oncogenic pathway
- Management of the hematologic manifestations of HIV disease
- Expression of CDK4 or CDK2 in mouse oral cavity is retained in adult pituitary with distinct effects on tumorigenesis
- ANALYSIS/PROSPECTS
- Stromal pleiotrophin regulates repopulation behavior of hematopoietic Stem cells
- Physiological relevance of cell cycle kinases
- The SKP2 E3 ligase regulates basal homeostasis and stress-induced regeneration of HSCs
- Sequential administration of interleukin-3 and granulocyte-macrophage colony-stimulating factor following intensified, accelerated CEE (cyclophosphamide …
- Enrichment of functionally distinct mouse hematopoietic progenitor cell populations using CD62L
- Beta 2 agonists and asthma.
- Blood progenitor cell (BPC) mobilization studied in multiple myeloma, solid tumor and non-Hodgkin’s lymphoma patients after combination chemotherapy and G-CSF
- Sparing of extraocular muscle in aging and muscular dystrophies: a myogenic precursor cell hypothesis
- Towards cure of CML: why we need to know more about CML Stem cells?
- Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
- The Role of Hox Transcription Factors in the Regulation of Hematopoiesis
- Highlights of the 2007 Progeria Research Foundation scientific workshop: progress in translational science
- KRASG12V enhances proliferation and initiates myelomonocytic differentiation in human Stem/progenitor cells via intrinsic and extrinsic pathways
- The molecular basis of cutaneous aging
- MicroRNA-101 negatively regulates Ezh2 and its expression is modulated by androgen receptor and HIF-1α/HIF-1β
- Hyaluronic acid facilitates the recovery of hematopoiesis following 5‐fluorouracil administration
- Epigenetics: prenatal exposure to genistein leaves a permanent signature on the hematopoietic lineage
- Diabetes induced changes in rat mesenchymal Stem cells
- Epigenetic corruption of VDR signalling in malignancy
- Intra-articular injections in capsulitis
- Combined epigenetic therapy with the histone methyltransferase EZH2 inhibitor 3-deazaneplanocin A and the histone deacetylase inhibitor panobinostat against …
- B-lymphocyte commitment: identifying the point of no return
- Effects of recombinant human granulocyte colony‐stimulating factor on leucopenia in zidovudine‐treated patients with AIDS and AIDS related complex, a phase I/II …
- Probing the mitotic history and developmental stage of hematopoietic cells using single telomere length analysis (STELA)
- Ex vivo culture of Fancc-/- Stem/progenitor cells predisposes cells to undergo apoptosis, and surviving Stem/progenitor cells display cytogenetic abnormalities and an …
- Telomere length dynamics in normal and malignant hematopoiesis
- Hematopoietic growth factors in transplantation: Biology and applications
- Reduction in the duration of myelotoxicity associated with radioimmunotherapy with infusions of the hemoregulatory peptide, HP5b in mice
- Recombinant human granulocyte colony-stimulating factor in the management of cancer patients: five years on
- Hematopoietic Stem cells
- Intrinsic and Microenvironmental Defects Are Involved in the Age-Related Changes of Lin−c-kit+ Hematopoietic Progenitor Cells
- Relationships between hematopoiesis and hepatogenesis in the midtrimester fetal liver characterized by dynamic transcriptomic and proteomic profiles
- Apoptotic regulation in primitive hematopoietic precursors
- Theories and mechanisms of aging
- 11 Blood compared to marrow as a source of allogeneic hematopoietic Stem cells for
- RUNX1 Mutations in Clonal Myeloid Disorders: From Conventional Cytogenetics to Next Generation Sequencing, A Story 40 Years in the Making
- Without Hemopoietic cell Support
- Human somatic mutation rate estimated from SNP chips
- The use of hematopoietic growth factors to support cytotoxic chemotherapy for patients with breast cancer
- Telomere dynamics in childhood leukemia and solid tumors: a follow-up study
- EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence
- Polycomb protein Ezh2 regulates pancreatic β-cell Ink4a/Arf expression and regeneration in diabetes mellitus
- The role of DNA damage and repair in aging: new approaches to an old problem
- Proliferation Society Meeting
- The polycomb gene BMI1 in normal hematopoiesis and leukemia
- The high functionalization of temperature-responsive culture dishes for establishing advanced cell sheet engineering
- Haemopoietic growth factors and dose intensity in high-grade and intermediate-grade lymphoma
- Eosinophils, but not neutrophils, exibit an efficient DNA repair machinary and high nucleolar activity
- PTEN loss in the continuum of common cancers, rare syndromes and mouse models
- Insulin signaling and life span
- Polycomb proteins in mammalian cell differentiation and plasticity
- The genetics of dyskeratosis congenita
- Stimulation of myelopoiesis in Lister a monocytogenes-infected mice by an aggregated polymer isolated from Asp ergillus oryzae
- High-efficiency retroviral gene transfer into murine high-proliferative-potential cells cycle-activated by cytosine arabinoside
- Perturbation in the ability of bone marrow stroma from patients with acute myeloid leukemia but not chronic myeloid leukemia to support normal early hematopoietic …
- Emerin and the nuclear lamina in muscle and cardiac disease
- Radiation-induced Hemopoietic and Immune Dysfunction
- Telomere length in Hutchinson-Gilford progeria syndrome
- A Randomized Phase-II Study of BB-10010 (Macrophage Inflammatory Protein-1) in Patients With Advanced Breast Cancer Receiving 5-Fluorouracil, Adriamycin …
- Anemia, Paroxysmal Nocturnal Hemoglobinuria, Pure Red Blood cell
- Cancer Initiating Cells in Head and Neck Squamous cell Carcinoma
- Therapy with recombinant human erythropoietin in patients with myelodysplastic syndromes
- XXIII International Association for Comparative Research on Leukemia and Related Diseases Symposium: from Molecular Pathogenesis to Targeted Therapy in …
- An examination of ethical issues raised in the pretreatment of normal volunteer granulocyte donors with granulocyte colony-stimulating factor
- Telomere binding proteins including TRF1 and TRF2 (indicated by light and
- Granulocyte colony-stimulating factor (G-CSF) prevents dose-limiting neutropenia in lymphoma patients receiving standard dose chemotherapy
- Reduction in carboplatin hematopoietic toxicity in tumor bearing mice: comparative mechanisms and effects of interleukin-1β and corticosteroids
- Functions of Pleiotrophin in the Regulation of Hematopoiesis
- Therapy for Fanconi Anemia
- HGPS and related premature aging disorders: from genomic identification to the first therapeutic approaches
- Hematopoietic growth factors in cancer treatment
- Ku, Artemis, and ataxia-telangiectasia-mutated: signalling networks in DNA damage
- Defective Notch activation in microenvironment leads to myeloproliferative disease
- Myostatin Propeptide Gene Delivery by Adeno-Associated Virus Serotype 8 Vectors Enhances Muscle Growth and Ameliorates Dystrophic Phenotypes in mdx Mice
- The role of haemopoietic growth factors in bone marrow transplantation
- The role of hematopoietic growth factors in small cell lung cancer: a review
- Pathophysiology and treatment of acquired
- Recombinant human interleukin-1 receptor antagonist protects early myeloid progenitors in a murine model of cyclophosphamide-induced myelotoxicity
- NCI’s provocative questions on cancer: some answers to ignite discussion
- Regulation of senescence in cancer and aging
- Telomere elongation followed by telomere length reduction, in leukocytes from divers exposed to intense oxidative stress–implications for tissue and organismal aging
- Diffuse plasmacytosis in a child with brainStem glioma following multiagent chemotherapy and intensive growth factor support
- The design of differentiation therapies
- Effect of recombinant human granulocyte-macrophage colony-stimulating factor on hematopoietic reconstitution after high-dose chemotherapy and autologous bone …
- The p38 mitogen-activated protein kinase pathway in interferon signal transduction
- Vascular progenitor cells: origin and mechanisms of mobilization, differentiation, integration, and vasculogenesis
- The role of apoptosis, proliferation, and the Bcl-2–related proteins in the myelodysplastic syndromes and acute myeloid leukemia secondary to MDS
- Telomeres and telomerase in adrenocortical tissue maintenance, carcinogenesis, and aging
- Identification and Characterization of Tumour Initiating Cells From Gynaecological Malignancies
- Pretreatment with granulocyte colony-stimulating factor reduces myelopoiesis in irradiated mice
- Effects of adenosine A3 receptor agonist on bone marrow granulocytic syStem in 5-fluorouracil-treated mice
- Biology of the Mi-2/NuRD complex in SLAC (Stemness, longevity/ageing, and cancer)
- Frequency Analysis of Multidrug Resistance-1 Gene Transfer into Human Primitive Hematopoietic Progenitor Cells Using the Cobblestone Area-Forming cell Assay …
- Epigenetic factors in cancer development: polycomb group proteins
- Genomic instability in incuded Stem cells and regulation of P14ARF expression
- Final checkup of neoplastic DNA replication: Evidence for failure in decision-making at the mitotic cell cycle checkpoint G1/S
- Transient monoparesis following blade plate removal in a Hutchinson-Gilford progeria syndrome patient. A case report
- Aging and cancer: can mTOR inhibitors kill two birds with one drug?
- Theoretical Paper: Exploring Overlooked Natural Mitochondria-Rejuvenative Intervention: The Puzzle of Bowhead Whales and Naked Mole Rats
- General introduction: Epigenetic programming by Polycomb group (PcG) proteins throughout development
- Erythropoietin and Wnt1 govern pathways of mTOR, Apaf-1, and XIAP in inflammatory microglia
- Basic Science of Breast Cancer in Older Patients
- Defective DSB repair correlates with abnormal nuclear morphology and is improved with FTI treatment in Hutchinson-Gilford progeria syndrome fibroblasts
- TOR signaling never gets old: aging, longevity and TORC1 activity
- Akt signaling maintains survival and proliferation in immature T cells and hematopoietic Stem cells
- Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin
- CXCR4 and mobilization of hematopoietic precursors
- The regulation of mammary prolactin receptor metabolism by a retroviral envelope protein
- PI3Kδ inhibitors in cancer: rationale and serendipity merge in the clinic
- The role of the homeobox gene Hhex in definitive hematopoietic progenitor proliferation and differentiation
- The importance of the telomere and telomerase syStem in hematological malignancies
- Anatomy and physiology of hematopoiesis
- Analysis of developmentally programmed changes in hematopoietic Stem cells
- The Role of BMP Signaling and Endoglin in Regulation of Hematopoiesis
- Large scale gene expression profiles of regenerating inner ear sensory epithelia
- Genetically determined syndromes associated with premature aging
- The regulation of self-renewal in hematopoietic regeneration and malignancy
- Dose adjustment and supportive care before and during treatment
- A phase I/II trial of recombinant granulocyte-macrophage colony-stimulating factor for children with aplastic anemia
- Gene expression profiling for adult human olfactory neuroepithelial-derived progenitors
- Growth-inhibiting N-substituted endogenous peptides
- Alpha sarcoglycan is required for FGF-dependent myogenic progenitor cell proliferation in vitro and in vivo
- Current status of retroviral vector mediated gene transfer into human hematopoietic Stem cells
- The DNA damage response: making it safe to play with knives
- Requirement of the transcription factor and onco-protein Gfil for the development and function of hematopoietic Stem cells and progenitor cells
- EZH2 is over-expressed in SCLC as a result of genomic deregulation of the Rb/E2F pathway.
- EZH2 depletion blocks the proliferation of colon cancer cells
- Identification and characterisation of novel haemopoietic gene products derived from murine embryonal Stem cells
- Functional interactions between Lmo2, the Arf tumor suppressor, and Notch1 in murine T-cell malignancies
- Laminopathies and A-type lamin-associated signalling pathways
- Control of mRNA Translation in Erythropoiesis
- Visualizing the dynamics of p21Waf1/Cip1 cyclin-dependent kinase inhibitor expression in living animals
- The role of the transcription factor 3 gene product E47 in multipotent hematopoietic Stem cells and progenitors
- Therapeutic Modulation of DNA Damage and Repair Mechanisms in Blood Cells
- Stromal cell –immune cell interactions
- Polycomb group genes as epigenetic regulators of normal and leukemic hemopoiesis
- Therapy Approach of Neurodegenerative Disorders by Bone Marrow Stem Cells
- Aging and TOR: interwoven in the fabric of life
- DNA damage, somatic aneuploidy, and malignant sarcoma susceptibility in muscular dystrophies
- Mouse models in aging research
- Disposable end tidal carbon dioxide detectors.
- Transcription factors, chromatin and cancer
- T cell function in the aged: Lessons learned from animal models
- FLIP: a novel regulator of macrophage differentiation and granulocyte homeostasis
- A phase I/II trial of recombinant human interleukin‐6 in patients with aplastic anaemia
- Hyphal Development in Candida albicans Requires Two Temporally Linked Changes in Promoter Chromatin for Initiation and Maintenance
- Stress responses of human dermal fibroblasts exposed to zinc pyrithione
- Walking in old age and development of metabolic syndrome: the health, aging, and body composition study
- The latest waves in calcium signaling
- Leukemias: principles and practice of therapy
- Alterations in chromatin are associated with increases in collagen III expression in aging nephropathy
- Accelerated features of age-related bone loss in zmpste24 metalloproteinase-deficient mice
- Embryonic senescence and laminopathies in a progeroid zebrafish model
- Mitochondrial ROS Generation and Its Regulation: Mechanisms Involved in H2O2 Signaling
- The investigation of macrophage inflammatory protein-1α as a myeloprotective agent
- A panel of monoclonal antibodies against human polycomb group proteins
- Effects of caloric restriction on cell proliferation in several tissues in mice: role of intermittent feeding
- The Hematopoietic Microenvironment
- 752Tissue Regeneration and Wound Healing
- Duchenne muscular dystrophy gene therapy: Lost in translation?
- Regulation of immune responses and hematopoiesis by the Rap1 signal
- Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo model for genetically transferred chemoprotection
- Genetic analysis of mammalian cyclin-dependent kinases and their inhibitors
- Genetic and pharmacologic regulation of cyclin dependent kinase 4 and 6 activity in mammalian hematopoiesis
- Physical activity and telomere biology: exploring the link with aging-related disease prevention
- Hypertension, obesity, and inflammation: the complex designs of a deadly trio
- 13 Aging and Intrinsic Aging: Pathogenesis and Manifestations
- Postgraduate haematology
- Gene transfer of multidrug resistance into a factor-dependent human hematopoietic progenitor cell line: in vivo…
- Bridging the gap between clinical trials of antiplatelet therapies and applications among elderly patients
- The effect of vascular aging on cancer progression and metastasis
- PI3K/mTOR signaling regulates prostatic branching morphogenesis
- Pancytopenia and the hypocellular bone marrow
- Workshop on immunizations in older adults: identifying future research agendas
- Early Blood cell Formation
- The role of the histone methyltransferase egg/dSETDB1 in Drosophilia development and oogenesis
- Hematologic Disorders in the Elderly
- Fragments of functional proteins: role in endocrine regulation
- Cytokine regulation of hematopoietic Stem cells and lymphopoiesis
- Effects of white adipose tissue grafts on total body fat and cellularity are dependent on graft type and location
- Spontaneous abrogation of the G2 DNA damage checkpoint has clinical benefits but promotes leukemogenesis in Fanconi anemia patients
- Biodegradabable [sic] endovascular stents: fulfilling the mission and then stepping away
- Analysis of murine mammary epithelial cellular hierarchy
- Chemoprotection by transfer of resistance genes
- Statin’s excitoprotection is mediated by sAPP and the subsequent attenuation of calpain-induced truncation events, likely via rho-ROCK signaling
- Distinct Roles of Cellular Copper and Erythropoietin Receptor on Hematopoietic Engraftment
- Lehrstuhl für Entwicklungsgenetik
- The role of the TSC-mTOR pathway on the regulation of the hematopoietic Stem cells
- Characterization of perforin and Fas ligand effector and regulatory T cell functions in allogeneic bone marrow transplantation
- G1 phase control and cell differentiation
- The effects of physiological adaptations to calorie restriction on global cell proliferation rates
- Programmed cell Death and Its Role in Neurological Disease
- PI3K𝛅 Inhibitors in Cancer: Rationale and Serendipity Merge in the Clinic
- Handbook of Experimental Pharmacology
- Telomeres: hallmarks of radiosensitivity
- The role of telomerase in age-related degenerative disease and cancer
- Animal models of human genetic diseases: do they need to be faithful to be useful?
- The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity
- DNA Damage
- The Influence of MIP-1α and Its Receptors in Haemopoiesis
- Chromatin structure regulation in transforming growth factor-β-directed epithelial-mesenchymal transition
- Regulation of Stem cells and neurogenesis in the adult olfactory epithelium
- Identification, isolation and ex vivo expansion of haemopoietic progenitor and Stem cells
- Polycomb group protein Ezh2 regulates pancreas regeneration and neoplasia
- Mouse models for understanding the molecular mechanism of bone disease in Hutchinson-Gilford progeria syndrome
- Double Strand Break Signaling in Health and Diseases
- Bibliography Current World Literature Vol 14 No 4 July 2007
- CLINICAL RESEARCH PROJECT
- Telomere length and dynamics in Hutchinson-Gilford progeria syndrome
- Effects of Physiologic, Metabolic and Molecular Adaptations to Calorie Restriction on Biomarkers of Longevity
- Roles for E2F in mouse hematopoiesis and pancreas homeostasis
- 1 3 Hematopoietic Growth Factors
- The role of the RhoA/rho-kinase pathway in pulmonary hypertension
- Osteogenesis imperfecta
- Genomic approaches for pathway identification in regenerating sensory epithelia of the inner ear
- Les syndromes lipodystrophiques: des adipopathies congénitales ou acquises
- Nuclear lamins: major factors in the structural organization and
- International Workshop” From Homo sapiens to Homo sapiens liberatus
- cell cycle and cancer: the G1 restriction point and the G1/S transition
- TO ALLOMETRY AND SURVIVORSHIP
- The Role of CDKs in Normal and Neoplastic Proliferation
- Mechanisms of Gfi-1 mediated transcriptional repression
- Non-integrating integrase and long terminal repeat attachment site mutant HIV-1-derived lentiviral vectors
- Cancer Genome and DNA Repair
- Cancer, Senescence, and Aging: Translation from Basic Research to Clinics
- hGTSE-1 Protein Unveils a New Pathway that Regulates p21CIP1/WAF1 Stability and Subcellular Localization
- Role of the Transcription Factor Zfx in T cell Homeostasis
- Phospho-regulation of the DNA Damage Response Kinase ATR
- Spatial, temporal and reversible regulation of endogenous genes in vivo using RNA interference
- Genetic studies of familial myeloproliferative disorders
- Accelerated aging in COPD: the relationship of telomere length and mortality in COPD
- Investigations of Polyamine Function Using Transgenic Mouse Models with Spermidine Synthase and S-adenosylmethionine Decarboxylase Overexpression
- hGTSE1 protein unveils new pathways that regulate apoptosis and cell motility
- DNA sequence and chromatin directed compartmentalization of chromosomal domains to the nuclear lamina
- Role of the MUTYH protein in the response to oxidative damage to DNA
- Characterisation of the role of the transcription factor Gfi-1B in haematopoiesis
- JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING 33 (4): 474-482, 2006 UMCG Disciplinegroep: NUC Annovazzi, A., Bonanno, E., Arca, M., D’ …
- The effect of maternal malaria during pregnancy on birth size, early childhood growth and blood pressure in Nigerian children
- Macrophage Inflammatory Protein-1&alpha: An Inhibitor of Clonogenic Epidermal Keratinocyte Proliferation?
- CTC1 deletion results in defective telomere replication, leading to catastrophic telomere loss and Stem cell exhaustion
- Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult Stem cell exhaustion
- Loss of aryl hydrocarbon receptor promotes gene changes associated with premature hematopoietic Stem cell exhaustion and development of a myeloproliferative …
- C/EBPβ promotes BCR–ABL-mediated myeloid expansion and leukemic Stem cell exhaustion
- Age-specific bone tumour incidence rates are governed by Stem cell exhaustion influencing the supply and demand of progenitor cells
- Control of the epithelial Stem cell epigenome: the shaping of epithelial Stem cell identity
- aPKCλ controls epidermal homeostasis and Stem cell fate th
