Harnessing NEUROPLASTICITY for clinical applications NEUROPLASTICITY in children Conceptualizing functional NEUROPLASTICITY Homer2 is necessary for EtOH-induced NEUROPLASTICITY Stress, depression, and NEUROPLASTICITY: a convergence of mechanisms Threoretical aspects of NEUROPLASTICITY Toward a theory of NEUROPLASTICITY Antidepressants and NEUROPLASTICITY Mitochondria and NEUROPLASTICITY Central NEUROPLASTICITY and pathological pain NEUROPLASTICITY subserving motor skill learning NEUROPLASTICITY mediated by altered gene expression The musician's brain as a model of NEUROPLASTICITY Learning in the fast lane: new insights into NEUROPLASTICITY Training-induced NEUROPLASTICITY in young children Invited Review: NEUROPLASTICITY in respiratory motor control Natural rewards, NEUROPLASTICITY, and non-drug addictions Contribution of central NEUROPLASTICITY to pathological pain: review of clinical and experimental evidence Evidence for four forms of NEUROPLASTICITY Mitochondria in NEUROPLASTICITY and neurological disorders Social influences on NEUROPLASTICITY: stress and interventions to promote well-being NEUROPLASTICITY: from MRI to depressive symptoms NEUROPLASTICITY and rehabilitation NEUROPLASTICITY and cellular resilience in mood disorders Drug addiction as a pathology of staged NEUROPLASTICITY Transcranial magnetic stimulation and NEUROPLASTICITY The dark side of NEUROPLASTICITY Buddha's brain: NEUROPLASTICITY and meditation [in the spotlight] The dynamic brain: NEUROPLASTICITY and mental health Alterations of NEUROPLASTICITY in depression: the hippocampus and beyond NEUROPLASTICITY in Alzheimer's disease NEUROPLASTICITY and swallowing NEUROPLASTICITY in the context of motor rehabilitation after stroke Principles of NEUROPLASTICITY and behavior Developmental NEUROPLASTICITY after cochlear implantation Corticosteroid receptors and NEUROPLASTICITY NEUROPLASTICITY and its applications for rehabilitation What blindness can tell us about seeing again: merging NEUROPLASTICITY and neuroprostheses NEUROPLASTICITY in mood disorders Dynamic network connectivity: a new form of NEUROPLASTICITY Structural and functional NEUROPLASTICITY in relation to traumatic stress Stress during development: Impact on NEUROPLASTICITY and relevance to psychopathology NEUROPLASTICITY failure in Alzheimer's disease: bridging the gap between plaques and tangles Exercise and NEUROPLASTICITY in persons living with Parkinson's disease NEUROPLASTICITY promoted by task complexity Studies of NEUROPLASTICITY with transcranial magnetic stimulation Functional and structural imaging of pain-induced NEUROPLASTICITY NEUROPLASTICITY, psychosocial genomics, and the biopsychosocial paradigm in the 21st century NEUROPLASTICITY and functional recovery in multiple sclerosis NEUROPLASTICITY of neocortical circuits in schizophrenia NEUROPLASTICITY and brain repair after stroke Modification of hippocampal neurogenesis and NEUROPLASTICITY by social environments Enteric NEUROPLASTICITY evoked by inflammation NEUROPLASTICITY—exercise-induced response of peripheral brain-derived neurotrophic factor D1-receptor impact on NEUROPLASTICITY in humans Harnessing NEUROPLASTICITY for clinical applications Brain damage and NEUROPLASTICITY: mechanisms of recovery or development? Neural interface technology for rehabilitation: exploiting and promoting NEUROPLASTICITY Sex differences in cortical NEUROPLASTICITY in humans NEUROPLASTICITY in the mesolimbic dopamine system and cocaine addiction Vulnerability to depression: from brain NEUROPLASTICITY to identification of biomarkers Preemptive analgesia. Clinical evidence of NEUROPLASTICITY contributing to postoperative pain. Dynamic NEUROPLASTICITY after human prefrontal cortex damage NEUROPLASTICITY and cognitive aging: the scaffolding theory of aging and cognition NEUROPLASTICITY and constraint-induced movement therapy Cellular mechanisms of NEUROPLASTICITY NEUROPLASTICITY signaling pathways linked to the pathophysiology of schizophrenia Systems NEUROPLASTICITY in the aging brain: recruiting additional neural resources for successful motor performance in elderly persons NEUROPLASTICITY following non-penetrating traumatic brain injury Stress risk factors and stress-related pathology: NEUROPLASTICITY, epigenetics and endophenotypes Impairments of NEUROPLASTICITY and cellular resilience in severe mood disorders: implications for
CATALASE The mechanism of CATALASE action. I. Steady-state analysis CATALASE activity Some variables affecting the measurement of “CATALASE activity” in soil A spectrophotometric method for measuring the breakdown of hydrogen peroxide by CATALASE Perborate as substrate in a new assay of CATALASE On the mechanism of the decomposition of hydrogen peroxide by CATALASE CATALASE photoinactivation The molecular weight of crystalline CATALASE Photometric determination of CATALASE activity The reaction between aminotriazole and CATALASE New method for CATALASE determination Hydrogen peroxide formation and CATALASE activity in the lactic acid bacteria CATALASE: kinetics of photooxidation Effect of temperature on CATALASE activity A study of the inhibition of CATALASE by 3-amino-1: 2: 4-triazole An intermediate compound in the CATALASE-hydrogen peroxide reaction Isoniazid-resistance and CATALASE activity of tubercle bacilli: a preliminary report The reactions of CATALASE in the presence of the notatin system The kinetics of CATALASE synthesis and destruction in vivo Reaction between CATALASE and hydrogen peroxide Crystalline bacterial CATALASE Effect of pH upon the reaction kinetics of the enzyme-substrate compounds of CATALASE Properties of CATALASE. Catalysis of coupled oxidation of alcohols CATALASE production by lactobacilli Purification of horse-radish peroxidase and comparison of its properties with those of CATALASE and methaemoglobin CATALASE. II The mechanism of CATALASE inhibitions CATALASE OF THE LACTOBACILLACEAE The effect of CATALASE on the inhibine and peroxide values of various honeys Production of CATALASE by the pediococci Activity of CATALASE in the red cell Dissociation of CATALASE into subunits Production of CATALASE changes in animals with 3-amino-1, 2, 4-triazole The enzyme-substrate compounds of bacterial CATALASE and peroxides On some properties of CATALASE haematin Liver CATALASE I. A manometric determination of CATALASE activity Denaturation of CATALASE by freezing and thawing The reactions of azide with CATALASE and their significance Studies on the CATALASE activity of acid-fast bacilli: I. An attempt to subgroup these organisms on the basis of their CATALASE activities at different temperatures and pH The state of CATALASE in the respiring bacterial cell Spectroscopy of CATALASE CATALASE assay with special reference to manometric methods On the detailed mechanism of a new type of CATALASE-like action The decomposition of hydrogen peroxide by liver CATALASE Dissociation of bovine liver CATALASE at low pH Further Studies of the Liver CATALASE A toxic cancer tissue constituent as evidenced by its effect on liver CATALASE activity Interrelationships of CATALASE, peroxidase, hematin, and chlorophyll Peroxidatic activity of CATALASE CATALASE studies on normal and cancerous rats The effect of pH upon the equilibria of CATALASE compounds Selectivity of sorbic acid media for the CATALASE negative lactic acid bacteria and clostridia CATALASE Studies on Isoniazid and Tubercle Bacilli, II. The Growth Requirements, CATALASE Activities, and Pathogenic Properties of Isoniazid-Resistant Mutants Studies on rat liver CATALASE II. Incorporation of 14C-leucine into CATALASE of liver cell fractions in vivo CATALASE, a new enzym of general occurrence An ultracentrifugal study of CATALASE Liver CATALASE Studies on rat liver CATALASE I. Combined immunochemical and enzymatic determination of CATALASE in liver cell fractions CATALASE, peroxidase and metmyoglobin as catalysts of coupled peroxidatic
Stress, CORTICOTROPIN -RELEASING FACTOR , and behavior Chemical and biological characterization of CORTICOTROPIN RELEASING FACTOR Psychiatric implications of basic and clinical studies with CORTICOTROPIN -RELEASING FACTOR CORTICOTROPIN -RELEASING FACTOR has an anxiogenic action in the social interaction test Effects of CORTICOTROPIN -RELEASING FACTOR and growth hormone-RELEASING FACTOR on sleep and activity in rats Influence of CORTICOTROPIN -RELEASING FACTOR on reproductive functions in the rat Behavioral effects of CORTICOTROPIN -RELEASING FACTOR : localization and characterization of central effects Isolation and sequence analysis of the human CORTICOTROPIN ‐RELEASING FACTOR precursor gene. CORTICOTROPIN -RELEASING FACTOR : actions on the sympathetic nervous system and metabolism Stress-induced inhibition of reproductive functions: role of endogenous CORTICOTROPIN -RELEASING FACTOR Characterization of rat hypothalamic CORTICOTROPIN -RELEASING FACTOR Primary structure of CORTICOTROPIN -RELEASING FACTOR from ovine hypothalamus CORTICOTROPIN RELEASING FACTOR decreases postburst hyperpolarizations and excites hippocampal neurons Interleukin-1 stimulates the secretion of hypothalamic CORTICOTROPIN -RELEASING FACTOR CORTICOTROPIN RELEASING FACTOR produces behavioural activation in rats CORTICOTROPIN -RELEASING FACTOR -producing neurons in the rat activated by interleukin-1 Elevated concentrations of CSF CORTICOTROPIN -RELEASING FACTOR -like immunoreactivity in depressed patients Intraventricular CORTICOTROPIN -RELEASING FACTOR enhances behavioral effects of novelty CORTICOTROPIN -RELEASING FACTOR receptors are widely distributed within the rat central nervous system: an autoradiographic study The role of CORTICOTROPIN -RELEASING FACTOR in the pathogenesis of major depression Immunocytochemical localization of CORTICOTROPIN ‐RELEASING FACTOR (CRF) in the rat brain In vivo CORTICOTROPIN -RELEASING FACTOR -induced secretion of adrenoCORTICOTROPIN , β-endorphin, and corticosterone Mediation by CORTICOTROPIN RELEASING FACTOR (CRF) of adenohypophysial hormone secretion [38] Assay of CORTICOTROPIN RELEASING FACTOR CORTICOTROPIN -RELEASING FACTOR immunoreactivity is widely distributed within the central nervous system of the rat: an immunohistochemical study CORTICOTROPIN -RELEASING FACTOR : effects on the autonomic nervous system and visceral systems. Hypothalamic control of adrenoCORTICOTROPIN secretion: advances since the discovery of 41-residue CORTICOTROPIN -RELEASING FACTOR Mechanisms of action of CORTICOTROPIN -RELEASING FACTOR and other regulators of CORTICOTROPIN release in rat pituitary cells. CORTICOTROPIN -RELEASING FACTOR receptors in the rat central nervous system: characterization and regional distribution CSF CORTICOTROPIN -RELEASING FACTOR -like immunoreactivity in depression and schizophrenia. CORTICOTROPIN -RELEASING FACTOR directly mediates colonic responses to stress Catecholaminergic modulation of CORTICOTROPIN -RELEASING FACTOR and adrenoCORTICOTROPIN secretion Reduced CORTICOTROPIN RELEASING FACTOR binding sites in the frontal cortex of suicide victims Distribution of CORTICOTROPIN -RELEASING FACTOR in rat brain. Organization of ovine CORTICOTROPIN -RELEASING FACTOR immunoreactive cells and fibers in the rat brain: an immunohistochemical study Clinical applications of CORTICOTROPIN -RELEASING FACTOR Interaction of CORTICOTROPIN -RELEASING FACTOR and Arginine Vasopressin on AdrenoCORTICOTROPIN Secretion in Vivo Physiological and behavioral responses to CORTICOTROPIN -RELEASING FACTOR administration: is CRF a mediator of anxiety or stress responses? CORTICOTROPIN -RELEASING FACTOR : effects on the sympathetic nervous system and oxygen consumption Synthetic competitive antagonists of CORTICOTROPIN -RELEASING FACTOR : effect on ACTH secretion in the rat CORTICOTROPIN -RELEASING FACTOR as the mediator of stress responses The CORTICOTROPIN -RELEASING FACTOR stimulation test: an aid in the evaluation of patients with Cushing's syndrome CORTICOTROPIN -RELEASING FACTOR potentiates acoustic startle in rats: blockade by chlordiazepoxide Effects of
TIME -Restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges TIME -Restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet TIME -Restricted feeding and risk of metabolic disease: a review of human and animal studies TIME -Restricted feeding attenuates age-related cardiac decline in Drosophila TIME -Restricted feeding entrains daily rhythms of energy metabolism in mice TIME -Restricted feeding and the realignment of biological rhythms: translational opportunities and challenges Night-TIME Restricted feeding normalises clock genes and Pai-1 gene expression in the db/db mouse liver The effects of TIME -Restricted feeding on lipid metabolism and adiposity Influence of a TIME -Restricted feeding schedule on the daily rhythm of abcb1a gene expression and its function in rat intestine Diet selection and eating behaviour of lactating goats subjected to TIME Restricted feeding in choice and single feeding system Long-term physiological alterations and recovery in a mouse model of separation associated with TIME -Restricted feeding : a tool to study anorexia nervosa … TIME -Restricted feeding of rapidly digested starches causes stronger entrainment of the liver clock in PER2:: LUCIFERASE knock-in mice TIME -Restricted feeding schedules modify temporal variation of gentamicin experimental nephrotoxicity The effect of TIME -Restricted demand feeding on feeding activity growth and feed conversion in rainbow trout (Oncorhynchus mykiss) The effects of feeding TIME and TIME -Restricted feeding on the fattening traits of White Roman geese Effect of two-step TIME -Restricted feeding on the fattening traits in geese Effects of feeding systems on social and feeding behavior and performance of finishing pigs Effect of Restricted feeding schedule on seasonal shifting of daily demand‐feeding pattern and food anticipatory activity in European sea bass (Dicentrarchus labrax L.) Diel feeding activity and the effect of TIME -Restricted self-feeding on growth and feed conversion in European sea bass feeding is not a more potent Zeitgeber than the light-dark cycle in Drosophila Reduction of anxiety after Restricted feeding in the rat: implication for eating disorders TIME -Restricted feeding of pigs: social and feeding behavior TIME -Restricted feeding and the realignment of Synchronization to light and Restricted -feeding schedules of behavioral and humoral daily rhythms in gilthead sea bream (Sparus aurata) TIME Restricted demand feeding of red sea bream, Pagrus major in outdoor tanks Quantitative analysis of light-phase Restricted feeding reveals metabolic dyssynchrony in mice The suprachiasmatic nuclei are involved in determining circadian rhythms during Restricted feeding Digestibility of different fiber fractions of diets with high and low fiber level for broilers on TIME -Restricted feeding Manipulation of feeding schedule can modify the circadian rhythms of toxicity and kinetics of theophylline in mice Intermittent fasting and human metabolic health Influence of the length of the daily feeding period on feed intake and growth of whitefish, Coregonus lavaretus Chronotoxicity and chronopharmacokinetics of methotrexate in mice: modification by feeding schedule Restricted feeding -induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice Effects of fluvoxamine on food intake during rebound hyperphagia in rats Chronopharmacokinetics of valproic acid following constant-rate
Hypothalamic IKKβ/NF-κB and ER stress link OVERNUTRITION to energy imbalance and obesity OVERNUTRITION Maternal and postnatal OVERNUTRITION differentially impact appetite regulators and fuel metabolism A global response to a global problem: the epidemic of OVERNUTRITION Neuroinflammation and neurodegeneration in OVERNUTRITION-induced diseases The burden of disease from undernutrition and OVERNUTRITION in countries undergoing rapid nutrition transition: a view from Brazil Childhood dual burden of under-and OVERNUTRITION in low-and middle-income countries: a critical review Epidemiologic evidence for the fetal OVERNUTRITION hypothesis: findings from the mater-university study of pregnancy and its outcomes Patterns, distribution, and determinants of under-and OVERNUTRITION: a population-based study of women in India Income inequality and the double burden of under-and OVERNUTRITION in India OVERNUTRITION. A burning question: does an adipokine-induced activation of the immune system mediate the effect of OVERNUTRITION on type 2 diabetes? Dietary-induced alterations in thyroid hormone metabolism during OVERNUTRITION. Carnitine insufficiency caused by aging and OVERNUTRITION compromises mitochondrial performance and metabolic control Developmental programming in response to maternal OVERNUTRITION Lipotoxicity, OVERNUTRITION and energy metabolism in aging Medicine, morality and mothering: Public health discourses on foetal alcohol exposure, smoking around children and childhood OVERNUTRITION OVERNUTRITION and skeletal disease: an experimental study in growing Great Dane dogs. X. Discussion Exploring the Developmental OVERNUTRITION Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable Maternal OVERNUTRITION impacts offspring adiposity and brain appetite markers‐modulation by postweaning diet Metabolic imprinting by prenatal, perinatal, and postnatal OVERNUTRITION: a review From chronic OVERNUTRITION to insulin resistance: the role of fat-storing capacity and inflammation Early OVERNUTRITION results in early-onset arcuate leptin resistance and increased sensitivity to high-fat diet Is obesity becoming a public health problem in India? Examine the shift from under‐to OVERNUTRITION problems over time Developmental OVERNUTRITION and obesity and type 2 diabetes in offspring The double burden of undernutrition and OVERNUTRITION in developing countries: an update Neonatal OVERNUTRITION causes early alterations in the central response to peripheral ghrelin Obesity, OVERNUTRITION and the immune system Transgenerational inheritance of glucose intolerance in a mouse model of neonatal OVERNUTRITION Mothers as smoking guns: Fetal OVERNUTRITION and the reproduction of obesity Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during OVERNUTRITION Pathogenesis of NASH: how metabolic complications of OVERNUTRITION favour lipotoxicity and pro-inflammatory fatty liver disease From chronic OVERNUTRITION to metaflammation and insulin resistance: adipose tissue and liver contributions Substantial intergenerational increases in body mass index are not explained by the fetal OVERNUTRITION hypothesis: the Cardiovascular Risk in Young Finns Study Nutritional status in acute stroke: undernutrition versus OVERNUTRITION in different stroke subtypes Postnatal early OVERNUTRITION changes the leptin signalling pathway in the hypothalamic–pituitary–thyroid axis of young and adult rats Double burden of diseases worldwide: Coexistence of undernutrition and OVERNUTRITION‐related non‐communicable chronic diseases OVERNUTRITION, mTOR signaling, and cardiovascular diseases Programmed metabolic syndrome: prenatal undernutrition and postweaning OVERNUTRITION The Society for Social Medicine John Pemberton Lecture 2011. Developmental OVERNUTRITION—an old hypothesis with new importance? OVERNUTRITION stimulates intestinal epithelium proliferation through β-catenin signaling in obese mice Nutritional status of 11–12-year-old Jamaican children: coexistence of under-and OVERNUTRITION
GLUCONEOGENESIS GLUCONEOGENESIS in cattle: significance and methodology Alanine: key role in GLUCONEOGENESIS Control of GLUCONEOGENESIS in liver: I. General features of GLUCONEOGENESIS in the perfused livers of rats Inhibition of hepatic GLUCONEOGENESIS by ethanol GLUCONEOGENESIS in the perfused rat liver Hepatic ketogenesis and GLUCONEOGENESIS in humans The hormonal control of hepatic GLUCONEOGENESIS Muscle amino acid metabolism and GLUCONEOGENESIS Regulation of GLUCONEOGENESIS by glucocorticoids. The rate of GLUCONEOGENESIS from various precursors in the perfused rat liver The regulation of glycolysis and GLUCONEOGENESIS in animal tissues Control of GLUCONEOGENESIS from amino acids in the perfused rat liver GLUCONEOGENESIS in the isolated perfused rat kidney Specific inhibition of GLUCONEOGENESIS by biguanides Nonsuppressability of GLUCONEOGENESIS by glucose in septic patients Control mechanisms of GLUCONEOGENESIS and ketogenesis: I. Effects of oleate on GLUCONEOGENESIS in perfused rat liver GLUCONEOGENESIS: methodological approaches in vivo. Mechanism for the stimulation of GLUCONEOGENESIS by fatty acids in perfused rat liver. Amino acid metabolism in the regulation of GLUCONEOGENESIS in man Renal GLUCONEOGENESIS. The effect of diet on the gluconeogenic capacity of rat-kidney-cortex slices Generation of extramitochondrial reducing power in GLUCONEOGENESIS Leigh's encephalomyelopathy: an inborn error of GLUCONEOGENESIS. Quantitative aspects of propionate metabolism and GLUCONEOGENESIS in sheep GLUCONEOGENESIS from alanine in patients with progressive malignant disease GLUCONEOGENESIS, ureagenesis and ketogenesis during sepsis. Metabolic Control of Enzymes Involved in Lipogenesis and GLUCONEOGENESIS* Cancer cachexia and GLUCONEOGENESIS The regulation of GLUCONEOGENESIS by diet and insulin in rainbow trout (Salmo gairdneri) Distribution of enzymes of glycolysis and GLUCONEOGENESIS in fish tissues Sex steroid influence on hepatic GLUCONEOGENESIS and glycogen formation Acceleration of renal GLUCONEOGENESIS by ketone bodies and fatty acids Interrelationships between GLUCONEOGENESIS and ureogenesis in isolated hepatocytes. A possible role for acetyl CoA in the control of GLUCONEOGENESIS Regulation of enzymes involved in GLUCONEOGENESIS Regulation of GLUCONEOGENESIS and glycolysis: studies of mechanisms controlling enzyme activity Differential sensitivity of glycogenolysis and GLUCONEOGENESIS to insulin infusions in dogs GLUCONEOGENESIS in arctic ground squirrels between periods of hibernation The effect of dietary composition and of insulin on GLUCONEOGENESIS in rainbow trout (Salmo gairdneri) Properties of phosphofructokinase from rat liver and their relation to the control of glycolysis and GLUCONEOGENESIS Regulation of GLUCONEOGENESIS in the guinea pig liver Inhibition of fatty acid stimulation of GLUCONEOGENESIS by (+)-decanoylcarnitine in perfused rat liver Control of glycolysis and GLUCONEOGENESIS in liver and kidney cortex Hormonal control of pyruvate kinase activity and of GLUCONEOGENESIS in isolated hepatocytes Muscle alanine synthesis and hepatic GLUCONEOGENESIS Depression of hepatic GLUCONEOGENESIS and the hypoglycemia of endotoxin shock Acceleration of GLUCONEOGENESIS from lactate by lysine Interaction of glucocorticoids with glucagon and epinephrine in the control of GLUCONEOGENESIS and glycogenolysis in liver and of lipolysis in adipose tissue GLUCONEOGENESIS AND PYRUVATE METABOLISM IN RAT KIDNEY, IN VITRO Blood glucose levels and GLUCONEOGENESIS in animals bearing transplantable tumors Effects of hypothalamic stimulation on GLUCONEOGENESIS and glycolysis in rat liver GLUCONEOGENESIS by the human kidney Paths of carbon in GLUCONEOGENESIS and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate. Effects of insulin and fatty acids on GLUCONEOGENESIS
Inhibition of Renal Glucose Reabsorption: a novel strategy for achieving Glucose control in type 2 diabetes mellitus Inhibition of Renal Glucose Reabsorption as a novel treatment for diabetes patients Renal Glucose Reabsorption inhibitors to treat diabetes Characterization of Renal Glucose Reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in Renal Glucose Reabsorption in humans Development of the Renal Glucose Reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2 Effect of Lepidium sativum L. on Renal Glucose Reabsorption and urinary TGF‐β1 levels in diabetic rats Selective SGLT2 Inhibition by tofogliflozin reduces Renal Glucose Reabsorption under hyperglycemic but not under hypo-or euglycemic conditions in rats Antihyperglycemic effect of T-1095 via Inhibition of Renal Na+-Glucose cotransporters in streptozotocin-induced diabetic rats Renal Glucose transporters: novel targets for hyperglycemia management Role of the kidney in normal Glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications Renal, metabolic and cardiovascular considerations of SGLT2 Inhibition Sodium-Glucose cotransporter-2 Inhibition and the glomerulus: a review From victim to ally: the kidney as an emerging target for the treatment of diabetes mellitus Type 2 sodium-Glucose cotransporter (SGLT2) inhibitors: from familial Renal glucosuria to the treatment of type 2 diabetes mellitus Inhibition of the intestinal sodium‐coupled Glucose transporter 1 (SGLT1) by extracts and polyphenols from apple reduces postprandial blood Glucose levels in mice … Glucose metabolism in the kidney: neurohormonal activation and heart failure development The role of the kidney and sodium-Glucose cotransporter-2 Inhibition in diabetes management Effect of phlorhizin on Renal Glucose and phosphate transport in the dog Exploring newer target sodium Glucose transporter 2 for the treatment of diabetes mellitus Glucose control by the kidney: an emerging target in diabetes Targeting Renal Glucose Reabsorption for the treatment of type 2 diabetes mellitus using the SGLT2 inhibitor dapagliflozin Inhibition of SGLT2: a novel strategy for treatment of type 2 diabetes mellitus Role of the Kidney in Type 2 Diabetes and Mechanism of Action of Sodium Glucose Cotransporter-2 Inhibitors Novel Indole-N-glucoside, TA-1887 As a Sodium Glucose Cotransporter 2 Inhibitor for Treatment of Type 2 Diabetes Dapagliflozin: a sodium Glucose cotransporter 2 inhibitor in development for type 2 diabetes SGLT2 Inhibition in diabetes mellitus: rationale and clinical prospects Effect of sodium-Glucose cotransport Inhibition on polycystic kidney disease progression in PCK rats Sodium Glucose co-transporter 2 (SGLT2) inhibitor Dapagliflozin twice daily or once daily: effect on pharmacokinetics and urinary Glucose excretion in healthy subjects The role of the kidneys in Glucose homeostasis in type 2 diabetes: clinical implications and therapeutic significance through sodium Glucose co-transporter 2 … SGLT2 Inhibition—a novel strategy for diabetes treatment Tofogliflozin, a potent and highly specific sodium/Glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice SGLT2 inhibitors: molecular design and potential differences in effect Antidiabetic effects of SGLT2-selective inhibitor ipragliflozin in streptozotocin–nicotinamide-induced mildly diabetic mice Sodium‐Glucose co‐transporter (SGLT) and Glucose transporter (GLUT) expression in the kidney of type 2 diabetic
- Phlorizin is a natural compound found in fruit trees that has been used for over 150 years in pharmaceutical and physiological research. - Its main pharmacological action is to produce renal glycosuria and block intestinal glucose absorption. - Phlorizin has played a significant role in the history of diabetes mellitus and has been used as a tool to study renal function. - It inhibits the sodium-glucose symporters (SGLTs) located in the proximal renal tubule and mucosa of the small intestine. - Phlorizin has potential uses in the treatment of diabetes, obesity, and stress hyperglycemia. - It improves insulin sensitivity and normalizes blood glucose levels in diabetic animals. - Phlorizin has antioxidant properties and may have potential cardiovascular benefits. - It has been studied for its potential use in the treatment of various conditions, including diabetes, cancer, and neurodegenerative diseases. PHLORIZIN: a review Correction of hyperglycemia with PHLORIZIN normalizes tissue sensitivity to insulin in diabetic rats. On the identity between the small intestinal enzymes PHLORIZIN hydrolase and glycosylceramidase Transcriptional regulation of the lactase-PHLORIZIN hydrolase gene by polymorphisms associated with adult-type hypolactasia A method for preparing C-glycosides related to PHLORIZIN Acute anti‐hyperglycaemic effects of an unripe apple preparation containing PHLORIZIN in healthy volunteers: a preliminary study Evaluation of the anti-inflammatory effects of phloretin and PHLORIZIN in lipopolysaccharide-stimulated mouse macrophages Reevaluation of renal tubular glucose transport inhibition by PHLORIZIN analogs PHLORIZIN prevents glomerular hyperfiltration but not hypertrophy in diabetic rats The action of PHLORIZIN on the excretion of glucose, xylose, sucrose, creatinine and urea by man Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase PHLORIZIN hydrolase Effects of PHLORIZIN and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia Probing the antioxidant potential of phloretin and PHLORIZIN through a computational investigation Complete primary structure of human and rabbit lactase‐PHLORIZIN hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme. Simultaneous separation and purification of total polyphenols, chlorogenic acid and PHLORIZIN from thinned young apples The human lactase‐PHLORIZIN hydrolase gene is located on chromosome 2 Regulation of lactase–PHLORIZIN hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2 PHLORIZIN-like effect of Fraxinus excelsior in normal and diabetic rats Energy-dependence of PHLORIZIN binding to isolated renal microvillus membranes Biosynthesis and maturation of lactase-PHLORIZIN hydrolase in the human small intestinal epithelial cells Insulin Sensitivity-Enhancing Activity of PHLORIZIN Is Associated with Lipopolysaccharide Decrease and Gut Microbiota Changes in Obese and Type 2 Diabetes (db/db … PHLORIZIN, a competitive inhibitor of glucose transport, facilitates memory storage in mice Hypothesis for the interaction of PHLORIZIN and phloretin with membrane carriers for sugars Normalization of blood glucose in diabetic rats with PHLORIZIN treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose … Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by PHLORIZIN during ischemia-reperfusion injury in mice Effect of PHLORIZIN on SGLT2 expression in the kidney of diabetic rats. Purification and characterisation of amphiphilic lactase/PHLORIZIN hydrolase from human small intestine PHLORIZIN as a probe of the small-intestinal
Calorie restriction—the SIR2 connection How does Calorie restriction work? Calorie restriction and aging: review of the literature and implications for studies in humans Aging, adiposity, and Calorie restriction Calorie restriction and SIR2 genes—towards a mechanism Requirement of NAD and SIR2 for life-span extension by Calorie restriction in Saccharomyces cerevisiae Sir2-independent life span extension by Calorie restriction in yeast Sir2 mediates longevity in the fly through a pathway related to Calorie restriction Calorie restriction and aging: A life‐history analysis Increase in activity during Calorie restriction requires Sirt1 Relative effects of Calorie restriction and weight loss in noninsulin-dependent diabetes mellitus Calorie restriction in rhesus monkeys The inflammation hypothesis of aging: molecular modulation by Calorie restriction Calorie restriction and cancer prevention: metabolic and molecular mechanisms Calorie restriction mimetics: an emerging research field Development of Calorie restriction mimetics as a prolongevity strategy Molecular mechanisms linking Calorie restriction and longevity Long-term Calorie restriction is highly effective in reducing the risk for atherosclerosis in humans Tissue-specific regulation of SIRT1 by Calorie restriction Calorie restriction and prevention of age-associated chronic disease Calorie restriction, SIRT1 and metabolism: understanding longevity Calorie restriction in primates: will it work and how will we know? Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans HST2 mediates SIR2-independent life-span extension by Calorie restriction SIR2: a potential target for Calorie restriction mimetics Mammalian sirtuins—emerging roles in physiology, aging, and Calorie restriction Nicotinamide and PNC1 govern lifespan extension by Calorie restriction in Saccharomyces cerevisiae Calorie restriction and the exercise of chromatin Molecular inflammation hypothesis of aging based on the anti‐aging mechanism of Calorie restriction Calorie restriction: what recent results suggest for the future of ageing research Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration Effect of Calorie restriction with or without exercise on body composition and fat distribution Oxidative stress and mitochondrial function with aging–the effects of Calorie restriction Calorie restriction alters mitochondrial protein acetylation Sir2 and Calorie restriction in yeast: a skeptical perspective Calorie restriction and stroke Intermittent versus daily Calorie restriction: which diet regimen is more effective for weight loss? SIRT1 transgenic mice show phenotypes resembling Calorie restriction Calorie restriction increases muscle mitochondrial biogenesis in healthy humans Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial Short-term Calorie restriction enhances skeletal muscle stem cell function Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency Effect of Calorie restriction on the metabolic history of chronologically aging yeast Calorie restriction: is AMPK a key sensor and effector? Tor1/Sch9-regulated carbon source substitution is as effective as Calorie restriction in life span extension NRF2, cancer and Calorie restriction Calorie restriction increases life span: a molecular mechanism Chronic Calorie restriction attenuates experimental autoimmune encephalomyelitis Calorie restriction and resveratrol in cardiovascular health and disease Calorie restriction extends yeast life span by lowering the level of NADH Calorie restriction and aging in nonhuman primates Mitochondria—a nexus for aging, Calorie restriction, and sirtuins? Calorie restriction: decelerating mTOR-driven aging from cells
Lipid droplets finally get a little RESPECT The life of Lipid droplets Lipid dropletsand cellular Lipidmetabolism TIP47 associates with Lipid droplets Lipid droplets at a glance The biophysics and cell biology of Lipid droplets Cell biology of Lipid droplets Lipid droplets: size matters A role for Lipid dropletsin inter‐membrane Lipid traffic Proteins under new management: Lipid droplets deliver Imaging of Lipidbiosynthesis: how a neutral Lipidenters Lipid droplets Lipid droplets: a unified view of a dynamic organelle Lipid droplets in inflammation and cancer Cidea is associated with Lipid droplets and insulin sensitivity in humans Controlling the size of Lipid droplets: Lipidand protein factors Lipid droplets: a classic organelle with new outfits TIP47 functions in the biogenesis of Lipid droplets The role of Lipid dropletsin metabolic disease in rodents and humans Phospholipids and Lipid droplets Perilipins, ADRP, and other proteins that associate with intracellular neutral Lipid dropletsin animal cells Isolating Lipid dropletsfrom multiple species Deformation of Lipid dropletsin fixed samples Balancing the fat: Lipid dropletsand human disease Lipid droplets: a dynamic organelle moves into focus Regulation of Lipid dropletsby autophagy Interactomic study on interaction between Lipid dropletsand mitochondria Lipid droplets: proteins floating on a pool of fat The surface of Lipid dropletsis a phosphoLipidmonolayer with a unique fatty acid composition Fluorescent detection of Lipid dropletsand associated proteins Live cell multicolor imaging of Lipid dropletswith a new dye, LD540 Nuclear Lipid droplets: a novel nuclear domain Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of Lipid droplets A role for phosphatidic acid in the formation of “supersized” Lipid droplets Coatomer-dependent protein delivery to Lipid droplets Minireview: Lipid dropletsin lipogenesis and lipolysis Nile red: a selective fluorescent stain for intracellular Lipid droplets. Structural determinants that target the hepatitis C virus core protein to Lipid droplets Proteomic analysis of proteins associated with Lipid dropletsof basal and lipolytically stimulated 3T3-L1 adipocytes Lipid dropletsinteract with mitochondria using SNAP23 Emerging roles for Lipid dropletsin immunity and host-pathogen interactions Fat on the move: intracellular motion of Lipid droplets Hepatic stellate cell Lipid droplets: a specialized Lipiddroplet for retinoid storage Triacylglycerol synthesis enzymes mediate Lipiddroplet growth by relocalizing from the ER to Lipid droplets Perilipin is located on the surface layer of intracellular Lipid dropletsin adipocytes. Influence of emulsifier type on in vitro digestibility of Lipid dropletsby pancreatic lipase Lipid droplets: FSP27 knockout enhances their sizzle Lipid dropletsand hepatitis C virus infection Fixation methods for the study of Lipid dropletsby immunofluorescence microscopy Identification of the major functional proteins of prokaryotic Lipid droplets Lipid dropletslighting up: insights from live microscopy The perilipin family of structural Lipiddroplet proteins: stabilization of Lipid dropletsand control of lipolysis The dynamic roles of intracellular Lipid droplets: from archaea to mammals FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular Lipid droplets Lipid dropletsas dynamic organelles connecting storage and efflux of lipids Emerging role of Lipid dropletsin host/pathogen interactions Network distribution of mitochondria and Lipid dropletsin human muscle fibres The emergence of