Stress, CORTICOTROPIN -RELEASING FACTOR , and behavior Chemical and biological characterization of CORTICOTROPIN RELEASING FACTOR Psychiatric implications of basic and clinical studies with CORTICOTROPIN -RELEASING FACTOR CORTICOTROPIN -RELEASING FACTOR has an anxiogenic action in the social interaction test Effects of CORTICOTROPIN -RELEASING FACTOR and growth hormone-RELEASING FACTOR on sleep and activity in rats Influence of CORTICOTROPIN -RELEASING FACTOR on reproductive functions in the rat Behavioral effects of CORTICOTROPIN -RELEASING FACTOR : localization and characterization of central effects Isolation and sequence analysis of the human CORTICOTROPIN ‐RELEASING FACTOR precursor gene. CORTICOTROPIN -RELEASING FACTOR : actions on the sympathetic nervous system and metabolism Stress-induced inhibition of reproductive functions: role of endogenous CORTICOTROPIN -RELEASING FACTOR Characterization of rat hypothalamic CORTICOTROPIN -RELEASING FACTOR Primary structure of CORTICOTROPIN -RELEASING FACTOR from ovine hypothalamus CORTICOTROPIN RELEASING FACTOR decreases postburst hyperpolarizations and excites hippocampal neurons Interleukin-1 stimulates the secretion of hypothalamic CORTICOTROPIN -RELEASING FACTOR CORTICOTROPIN RELEASING FACTOR produces behavioural activation in rats CORTICOTROPIN -RELEASING FACTOR -producing neurons in the rat activated by interleukin-1 Elevated concentrations of CSF CORTICOTROPIN -RELEASING FACTOR -like immunoreactivity in depressed patients Intraventricular CORTICOTROPIN -RELEASING FACTOR enhances behavioral effects of novelty CORTICOTROPIN -RELEASING FACTOR receptors are widely distributed within the rat central nervous system: an autoradiographic study The role of CORTICOTROPIN -RELEASING FACTOR in the pathogenesis of major depression Immunocytochemical localization of CORTICOTROPIN ‐RELEASING FACTOR (CRF) in the rat brain In vivo CORTICOTROPIN -RELEASING FACTOR -induced secretion of adrenoCORTICOTROPIN , β-endorphin, and corticosterone Mediation by CORTICOTROPIN RELEASING FACTOR (CRF) of adenohypophysial hormone secretion [38] Assay of CORTICOTROPIN RELEASING FACTOR CORTICOTROPIN -RELEASING FACTOR immunoreactivity is widely distributed within the central nervous system of the rat: an immunohistochemical study CORTICOTROPIN -RELEASING FACTOR : effects on the autonomic nervous system and visceral systems. Hypothalamic control of adrenoCORTICOTROPIN secretion: advances since the discovery of 41-residue CORTICOTROPIN -RELEASING FACTOR Mechanisms of action of CORTICOTROPIN -RELEASING FACTOR and other regulators of CORTICOTROPIN release in rat pituitary cells. CORTICOTROPIN -RELEASING FACTOR receptors in the rat central nervous system: characterization and regional distribution CSF CORTICOTROPIN -RELEASING FACTOR -like immunoreactivity in depression and schizophrenia. CORTICOTROPIN -RELEASING FACTOR directly mediates colonic responses to stress Catecholaminergic modulation of CORTICOTROPIN -RELEASING FACTOR and adrenoCORTICOTROPIN secretion Reduced CORTICOTROPIN RELEASING FACTOR binding sites in the frontal cortex of suicide victims Distribution of CORTICOTROPIN -RELEASING FACTOR in rat brain. Organization of ovine CORTICOTROPIN -RELEASING FACTOR immunoreactive cells and fibers in the rat brain: an immunohistochemical study Clinical applications of CORTICOTROPIN -RELEASING FACTOR Interaction of CORTICOTROPIN -RELEASING FACTOR and Arginine Vasopressin on AdrenoCORTICOTROPIN Secretion in Vivo Physiological and behavioral responses to CORTICOTROPIN -RELEASING FACTOR administration: is CRF a mediator of anxiety or stress responses? CORTICOTROPIN -RELEASING FACTOR : effects on the sympathetic nervous system and oxygen consumption Synthetic competitive antagonists of CORTICOTROPIN -RELEASING FACTOR : effect on ACTH secretion in the rat CORTICOTROPIN -RELEASING FACTOR as the mediator of stress responses The CORTICOTROPIN -RELEASING FACTOR stimulation test: an aid in the evaluation of patients with Cushing's syndrome CORTICOTROPIN -RELEASING FACTOR potentiates acoustic startle in rats: blockade by chlordiazepoxide Effects of
TIME -Restricted feeding is a preventative and therapeutic intervention against diverse nutritional challenges TIME -Restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet TIME -Restricted feeding and risk of metabolic disease: a review of human and animal studies TIME -Restricted feeding attenuates age-related cardiac decline in Drosophila TIME -Restricted feeding entrains daily rhythms of energy metabolism in mice TIME -Restricted feeding and the realignment of biological rhythms: translational opportunities and challenges Night-TIME Restricted feeding normalises clock genes and Pai-1 gene expression in the db/db mouse liver The effects of TIME -Restricted feeding on lipid metabolism and adiposity Influence of a TIME -Restricted feeding schedule on the daily rhythm of abcb1a gene expression and its function in rat intestine Diet selection and eating behaviour of lactating goats subjected to TIME Restricted feeding in choice and single feeding system Long-term physiological alterations and recovery in a mouse model of separation associated with TIME -Restricted feeding : a tool to study anorexia nervosa … TIME -Restricted feeding of rapidly digested starches causes stronger entrainment of the liver clock in PER2:: LUCIFERASE knock-in mice TIME -Restricted feeding schedules modify temporal variation of gentamicin experimental nephrotoxicity The effect of TIME -Restricted demand feeding on feeding activity growth and feed conversion in rainbow trout (Oncorhynchus mykiss) The effects of feeding TIME and TIME -Restricted feeding on the fattening traits of White Roman geese Effect of two-step TIME -Restricted feeding on the fattening traits in geese Effects of feeding systems on social and feeding behavior and performance of finishing pigs Effect of Restricted feeding schedule on seasonal shifting of daily demand‐feeding pattern and food anticipatory activity in European sea bass (Dicentrarchus labrax L.) Diel feeding activity and the effect of TIME -Restricted self-feeding on growth and feed conversion in European sea bass feeding is not a more potent Zeitgeber than the light-dark cycle in Drosophila Reduction of anxiety after Restricted feeding in the rat: implication for eating disorders TIME -Restricted feeding of pigs: social and feeding behavior TIME -Restricted feeding and the realignment of Synchronization to light and Restricted -feeding schedules of behavioral and humoral daily rhythms in gilthead sea bream (Sparus aurata) TIME Restricted demand feeding of red sea bream, Pagrus major in outdoor tanks Quantitative analysis of light-phase Restricted feeding reveals metabolic dyssynchrony in mice The suprachiasmatic nuclei are involved in determining circadian rhythms during Restricted feeding Digestibility of different fiber fractions of diets with high and low fiber level for broilers on TIME -Restricted feeding Manipulation of feeding schedule can modify the circadian rhythms of toxicity and kinetics of theophylline in mice Intermittent fasting and human metabolic health Influence of the length of the daily feeding period on feed intake and growth of whitefish, Coregonus lavaretus Chronotoxicity and chronopharmacokinetics of methotrexate in mice: modification by feeding schedule Restricted feeding -induced sleep, activity, and body temperature changes in normal and preproghrelin-deficient mice Effects of fluvoxamine on food intake during rebound hyperphagia in rats Chronopharmacokinetics of valproic acid following constant-rate
Hypothalamic IKKβ/NF-κB and ER stress link OVERNUTRITION to energy imbalance and obesity OVERNUTRITION Maternal and postnatal OVERNUTRITION differentially impact appetite regulators and fuel metabolism A global response to a global problem: the epidemic of OVERNUTRITION Neuroinflammation and neurodegeneration in OVERNUTRITION-induced diseases The burden of disease from undernutrition and OVERNUTRITION in countries undergoing rapid nutrition transition: a view from Brazil Childhood dual burden of under-and OVERNUTRITION in low-and middle-income countries: a critical review Epidemiologic evidence for the fetal OVERNUTRITION hypothesis: findings from the mater-university study of pregnancy and its outcomes Patterns, distribution, and determinants of under-and OVERNUTRITION: a population-based study of women in India Income inequality and the double burden of under-and OVERNUTRITION in India OVERNUTRITION. A burning question: does an adipokine-induced activation of the immune system mediate the effect of OVERNUTRITION on type 2 diabetes? Dietary-induced alterations in thyroid hormone metabolism during OVERNUTRITION. Carnitine insufficiency caused by aging and OVERNUTRITION compromises mitochondrial performance and metabolic control Developmental programming in response to maternal OVERNUTRITION Lipotoxicity, OVERNUTRITION and energy metabolism in aging Medicine, morality and mothering: Public health discourses on foetal alcohol exposure, smoking around children and childhood OVERNUTRITION OVERNUTRITION and skeletal disease: an experimental study in growing Great Dane dogs. X. Discussion Exploring the Developmental OVERNUTRITION Hypothesis Using Parental–Offspring Associations and FTO as an Instrumental Variable Maternal OVERNUTRITION impacts offspring adiposity and brain appetite markers‐modulation by postweaning diet Metabolic imprinting by prenatal, perinatal, and postnatal OVERNUTRITION: a review From chronic OVERNUTRITION to insulin resistance: the role of fat-storing capacity and inflammation Early OVERNUTRITION results in early-onset arcuate leptin resistance and increased sensitivity to high-fat diet Is obesity becoming a public health problem in India? Examine the shift from under‐to OVERNUTRITION problems over time Developmental OVERNUTRITION and obesity and type 2 diabetes in offspring The double burden of undernutrition and OVERNUTRITION in developing countries: an update Neonatal OVERNUTRITION causes early alterations in the central response to peripheral ghrelin Obesity, OVERNUTRITION and the immune system Transgenerational inheritance of glucose intolerance in a mouse model of neonatal OVERNUTRITION Mothers as smoking guns: Fetal OVERNUTRITION and the reproduction of obesity Gut-derived GIP activates central Rap1 to impair neural leptin sensitivity during OVERNUTRITION Pathogenesis of NASH: how metabolic complications of OVERNUTRITION favour lipotoxicity and pro-inflammatory fatty liver disease From chronic OVERNUTRITION to metaflammation and insulin resistance: adipose tissue and liver contributions Substantial intergenerational increases in body mass index are not explained by the fetal OVERNUTRITION hypothesis: the Cardiovascular Risk in Young Finns Study Nutritional status in acute stroke: undernutrition versus OVERNUTRITION in different stroke subtypes Postnatal early OVERNUTRITION changes the leptin signalling pathway in the hypothalamic–pituitary–thyroid axis of young and adult rats Double burden of diseases worldwide: Coexistence of undernutrition and OVERNUTRITION‐related non‐communicable chronic diseases OVERNUTRITION, mTOR signaling, and cardiovascular diseases Programmed metabolic syndrome: prenatal undernutrition and postweaning OVERNUTRITION The Society for Social Medicine John Pemberton Lecture 2011. Developmental OVERNUTRITION—an old hypothesis with new importance? OVERNUTRITION stimulates intestinal epithelium proliferation through β-catenin signaling in obese mice Nutritional status of 11–12-year-old Jamaican children: coexistence of under-and OVERNUTRITION
GLUCONEOGENESIS GLUCONEOGENESIS in cattle: significance and methodology Alanine: key role in GLUCONEOGENESIS Control of GLUCONEOGENESIS in liver: I. General features of GLUCONEOGENESIS in the perfused livers of rats Inhibition of hepatic GLUCONEOGENESIS by ethanol GLUCONEOGENESIS in the perfused rat liver Hepatic ketogenesis and GLUCONEOGENESIS in humans The hormonal control of hepatic GLUCONEOGENESIS Muscle amino acid metabolism and GLUCONEOGENESIS Regulation of GLUCONEOGENESIS by glucocorticoids. The rate of GLUCONEOGENESIS from various precursors in the perfused rat liver The regulation of glycolysis and GLUCONEOGENESIS in animal tissues Control of GLUCONEOGENESIS from amino acids in the perfused rat liver GLUCONEOGENESIS in the isolated perfused rat kidney Specific inhibition of GLUCONEOGENESIS by biguanides Nonsuppressability of GLUCONEOGENESIS by glucose in septic patients Control mechanisms of GLUCONEOGENESIS and ketogenesis: I. Effects of oleate on GLUCONEOGENESIS in perfused rat liver GLUCONEOGENESIS: methodological approaches in vivo. Mechanism for the stimulation of GLUCONEOGENESIS by fatty acids in perfused rat liver. Amino acid metabolism in the regulation of GLUCONEOGENESIS in man Renal GLUCONEOGENESIS. The effect of diet on the gluconeogenic capacity of rat-kidney-cortex slices Generation of extramitochondrial reducing power in GLUCONEOGENESIS Leigh's encephalomyelopathy: an inborn error of GLUCONEOGENESIS. Quantitative aspects of propionate metabolism and GLUCONEOGENESIS in sheep GLUCONEOGENESIS from alanine in patients with progressive malignant disease GLUCONEOGENESIS, ureagenesis and ketogenesis during sepsis. Metabolic Control of Enzymes Involved in Lipogenesis and GLUCONEOGENESIS* Cancer cachexia and GLUCONEOGENESIS The regulation of GLUCONEOGENESIS by diet and insulin in rainbow trout (Salmo gairdneri) Distribution of enzymes of glycolysis and GLUCONEOGENESIS in fish tissues Sex steroid influence on hepatic GLUCONEOGENESIS and glycogen formation Acceleration of renal GLUCONEOGENESIS by ketone bodies and fatty acids Interrelationships between GLUCONEOGENESIS and ureogenesis in isolated hepatocytes. A possible role for acetyl CoA in the control of GLUCONEOGENESIS Regulation of enzymes involved in GLUCONEOGENESIS Regulation of GLUCONEOGENESIS and glycolysis: studies of mechanisms controlling enzyme activity Differential sensitivity of glycogenolysis and GLUCONEOGENESIS to insulin infusions in dogs GLUCONEOGENESIS in arctic ground squirrels between periods of hibernation The effect of dietary composition and of insulin on GLUCONEOGENESIS in rainbow trout (Salmo gairdneri) Properties of phosphofructokinase from rat liver and their relation to the control of glycolysis and GLUCONEOGENESIS Regulation of GLUCONEOGENESIS in the guinea pig liver Inhibition of fatty acid stimulation of GLUCONEOGENESIS by (+)-decanoylcarnitine in perfused rat liver Control of glycolysis and GLUCONEOGENESIS in liver and kidney cortex Hormonal control of pyruvate kinase activity and of GLUCONEOGENESIS in isolated hepatocytes Muscle alanine synthesis and hepatic GLUCONEOGENESIS Depression of hepatic GLUCONEOGENESIS and the hypoglycemia of endotoxin shock Acceleration of GLUCONEOGENESIS from lactate by lysine Interaction of glucocorticoids with glucagon and epinephrine in the control of GLUCONEOGENESIS and glycogenolysis in liver and of lipolysis in adipose tissue GLUCONEOGENESIS AND PYRUVATE METABOLISM IN RAT KIDNEY, IN VITRO Blood glucose levels and GLUCONEOGENESIS in animals bearing transplantable tumors Effects of hypothalamic stimulation on GLUCONEOGENESIS and glycolysis in rat liver GLUCONEOGENESIS by the human kidney Paths of carbon in GLUCONEOGENESIS and lipogenesis: the role of mitochondria in supplying precursors of phosphoenolpyruvate. Effects of insulin and fatty acids on GLUCONEOGENESIS
Inhibition of Renal Glucose Reabsorption: a novel strategy for achieving Glucose control in type 2 diabetes mellitus Inhibition of Renal Glucose Reabsorption as a novel treatment for diabetes patients Renal Glucose Reabsorption inhibitors to treat diabetes Characterization of Renal Glucose Reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes Use of systems pharmacology modeling to elucidate the operating characteristics of SGLT1 and SGLT2 in Renal Glucose Reabsorption in humans Development of the Renal Glucose Reabsorption inhibitors: a new mechanism for the pharmacotherapy of diabetes mellitus type 2 Effect of Lepidium sativum L. on Renal Glucose Reabsorption and urinary TGF‐β1 levels in diabetic rats Selective SGLT2 Inhibition by tofogliflozin reduces Renal Glucose Reabsorption under hyperglycemic but not under hypo-or euglycemic conditions in rats Antihyperglycemic effect of T-1095 via Inhibition of Renal Na+-Glucose cotransporters in streptozotocin-induced diabetic rats Renal Glucose transporters: novel targets for hyperglycemia management Role of the kidney in normal Glucose homeostasis and in the hyperglycaemia of diabetes mellitus: therapeutic implications Renal, metabolic and cardiovascular considerations of SGLT2 Inhibition Sodium-Glucose cotransporter-2 Inhibition and the glomerulus: a review From victim to ally: the kidney as an emerging target for the treatment of diabetes mellitus Type 2 sodium-Glucose cotransporter (SGLT2) inhibitors: from familial Renal glucosuria to the treatment of type 2 diabetes mellitus Inhibition of the intestinal sodium‐coupled Glucose transporter 1 (SGLT1) by extracts and polyphenols from apple reduces postprandial blood Glucose levels in mice … Glucose metabolism in the kidney: neurohormonal activation and heart failure development The role of the kidney and sodium-Glucose cotransporter-2 Inhibition in diabetes management Effect of phlorhizin on Renal Glucose and phosphate transport in the dog Exploring newer target sodium Glucose transporter 2 for the treatment of diabetes mellitus Glucose control by the kidney: an emerging target in diabetes Targeting Renal Glucose Reabsorption for the treatment of type 2 diabetes mellitus using the SGLT2 inhibitor dapagliflozin Inhibition of SGLT2: a novel strategy for treatment of type 2 diabetes mellitus Role of the Kidney in Type 2 Diabetes and Mechanism of Action of Sodium Glucose Cotransporter-2 Inhibitors Novel Indole-N-glucoside, TA-1887 As a Sodium Glucose Cotransporter 2 Inhibitor for Treatment of Type 2 Diabetes Dapagliflozin: a sodium Glucose cotransporter 2 inhibitor in development for type 2 diabetes SGLT2 Inhibition in diabetes mellitus: rationale and clinical prospects Effect of sodium-Glucose cotransport Inhibition on polycystic kidney disease progression in PCK rats Sodium Glucose co-transporter 2 (SGLT2) inhibitor Dapagliflozin twice daily or once daily: effect on pharmacokinetics and urinary Glucose excretion in healthy subjects The role of the kidneys in Glucose homeostasis in type 2 diabetes: clinical implications and therapeutic significance through sodium Glucose co-transporter 2 … SGLT2 Inhibition—a novel strategy for diabetes treatment Tofogliflozin, a potent and highly specific sodium/Glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice SGLT2 inhibitors: molecular design and potential differences in effect Antidiabetic effects of SGLT2-selective inhibitor ipragliflozin in streptozotocin–nicotinamide-induced mildly diabetic mice Sodium‐Glucose co‐transporter (SGLT) and Glucose transporter (GLUT) expression in the kidney of type 2 diabetic
- Phlorizin is a natural compound found in fruit trees that has been used for over 150 years in pharmaceutical and physiological research. - Its main pharmacological action is to produce renal glycosuria and block intestinal glucose absorption. - Phlorizin has played a significant role in the history of diabetes mellitus and has been used as a tool to study renal function. - It inhibits the sodium-glucose symporters (SGLTs) located in the proximal renal tubule and mucosa of the small intestine. - Phlorizin has potential uses in the treatment of diabetes, obesity, and stress hyperglycemia. - It improves insulin sensitivity and normalizes blood glucose levels in diabetic animals. - Phlorizin has antioxidant properties and may have potential cardiovascular benefits. - It has been studied for its potential use in the treatment of various conditions, including diabetes, cancer, and neurodegenerative diseases. PHLORIZIN: a review Correction of hyperglycemia with PHLORIZIN normalizes tissue sensitivity to insulin in diabetic rats. On the identity between the small intestinal enzymes PHLORIZIN hydrolase and glycosylceramidase Transcriptional regulation of the lactase-PHLORIZIN hydrolase gene by polymorphisms associated with adult-type hypolactasia A method for preparing C-glycosides related to PHLORIZIN Acute anti‐hyperglycaemic effects of an unripe apple preparation containing PHLORIZIN in healthy volunteers: a preliminary study Evaluation of the anti-inflammatory effects of phloretin and PHLORIZIN in lipopolysaccharide-stimulated mouse macrophages Reevaluation of renal tubular glucose transport inhibition by PHLORIZIN analogs PHLORIZIN prevents glomerular hyperfiltration but not hypertrophy in diabetic rats The action of PHLORIZIN on the excretion of glucose, xylose, sucrose, creatinine and urea by man Dietary flavonoid and isoflavone glycosides are hydrolysed by the lactase site of lactase PHLORIZIN hydrolase Effects of PHLORIZIN and sodium on glucose-elicited alterations of cell junctions in intestinal epithelia Probing the antioxidant potential of phloretin and PHLORIZIN through a computational investigation Complete primary structure of human and rabbit lactase‐PHLORIZIN hydrolase: implications for biosynthesis, membrane anchoring and evolution of the enzyme. Simultaneous separation and purification of total polyphenols, chlorogenic acid and PHLORIZIN from thinned young apples The human lactase‐PHLORIZIN hydrolase gene is located on chromosome 2 Regulation of lactase–PHLORIZIN hydrolase gene expression by the caudal-related homoeodomain protein Cdx-2 PHLORIZIN-like effect of Fraxinus excelsior in normal and diabetic rats Energy-dependence of PHLORIZIN binding to isolated renal microvillus membranes Biosynthesis and maturation of lactase-PHLORIZIN hydrolase in the human small intestinal epithelial cells Insulin Sensitivity-Enhancing Activity of PHLORIZIN Is Associated with Lipopolysaccharide Decrease and Gut Microbiota Changes in Obese and Type 2 Diabetes (db/db … PHLORIZIN, a competitive inhibitor of glucose transport, facilitates memory storage in mice Hypothesis for the interaction of PHLORIZIN and phloretin with membrane carriers for sugars Normalization of blood glucose in diabetic rats with PHLORIZIN treatment reverses insulin-resistant glucose transport in adipose cells without restoring glucose … Expression of SGLT1 in human hearts and impairment of cardiac glucose uptake by PHLORIZIN during ischemia-reperfusion injury in mice Effect of PHLORIZIN on SGLT2 expression in the kidney of diabetic rats. Purification and characterisation of amphiphilic lactase/PHLORIZIN hydrolase from human small intestine PHLORIZIN as a probe of the small-intestinal
Calorie restriction—the SIR2 connection How does Calorie restriction work? Calorie restriction and aging: review of the literature and implications for studies in humans Aging, adiposity, and Calorie restriction Calorie restriction and SIR2 genes—towards a mechanism Requirement of NAD and SIR2 for life-span extension by Calorie restriction in Saccharomyces cerevisiae Sir2-independent life span extension by Calorie restriction in yeast Sir2 mediates longevity in the fly through a pathway related to Calorie restriction Calorie restriction and aging: A life‐history analysis Increase in activity during Calorie restriction requires Sirt1 Relative effects of Calorie restriction and weight loss in noninsulin-dependent diabetes mellitus Calorie restriction in rhesus monkeys The inflammation hypothesis of aging: molecular modulation by Calorie restriction Calorie restriction and cancer prevention: metabolic and molecular mechanisms Calorie restriction mimetics: an emerging research field Development of Calorie restriction mimetics as a prolongevity strategy Molecular mechanisms linking Calorie restriction and longevity Long-term Calorie restriction is highly effective in reducing the risk for atherosclerosis in humans Tissue-specific regulation of SIRT1 by Calorie restriction Calorie restriction and prevention of age-associated chronic disease Calorie restriction, SIRT1 and metabolism: understanding longevity Calorie restriction in primates: will it work and how will we know? Calorie restriction, aging, and cancer prevention: mechanisms of action and applicability to humans HST2 mediates SIR2-independent life-span extension by Calorie restriction SIR2: a potential target for Calorie restriction mimetics Mammalian sirtuins—emerging roles in physiology, aging, and Calorie restriction Nicotinamide and PNC1 govern lifespan extension by Calorie restriction in Saccharomyces cerevisiae Calorie restriction and the exercise of chromatin Molecular inflammation hypothesis of aging based on the anti‐aging mechanism of Calorie restriction Calorie restriction: what recent results suggest for the future of ageing research Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration Effect of Calorie restriction with or without exercise on body composition and fat distribution Oxidative stress and mitochondrial function with aging–the effects of Calorie restriction Calorie restriction alters mitochondrial protein acetylation Sir2 and Calorie restriction in yeast: a skeptical perspective Calorie restriction and stroke Intermittent versus daily Calorie restriction: which diet regimen is more effective for weight loss? SIRT1 transgenic mice show phenotypes resembling Calorie restriction Calorie restriction increases muscle mitochondrial biogenesis in healthy humans Calorie restriction or exercise: effects on coronary heart disease risk factors. A randomized, controlled trial Short-term Calorie restriction enhances skeletal muscle stem cell function Calorie restriction induces mitochondrial biogenesis and bioenergetic efficiency Effect of Calorie restriction on the metabolic history of chronologically aging yeast Calorie restriction: is AMPK a key sensor and effector? Tor1/Sch9-regulated carbon source substitution is as effective as Calorie restriction in life span extension NRF2, cancer and Calorie restriction Calorie restriction increases life span: a molecular mechanism Chronic Calorie restriction attenuates experimental autoimmune encephalomyelitis Calorie restriction and resveratrol in cardiovascular health and disease Calorie restriction extends yeast life span by lowering the level of NADH Calorie restriction and aging in nonhuman primates Mitochondria—a nexus for aging, Calorie restriction, and sirtuins? Calorie restriction: decelerating mTOR-driven aging from cells
Lipid droplets finally get a little RESPECT The life of Lipid droplets Lipid dropletsand cellular Lipidmetabolism TIP47 associates with Lipid droplets Lipid droplets at a glance The biophysics and cell biology of Lipid droplets Cell biology of Lipid droplets Lipid droplets: size matters A role for Lipid dropletsin inter‐membrane Lipid traffic Proteins under new management: Lipid droplets deliver Imaging of Lipidbiosynthesis: how a neutral Lipidenters Lipid droplets Lipid droplets: a unified view of a dynamic organelle Lipid droplets in inflammation and cancer Cidea is associated with Lipid droplets and insulin sensitivity in humans Controlling the size of Lipid droplets: Lipidand protein factors Lipid droplets: a classic organelle with new outfits TIP47 functions in the biogenesis of Lipid droplets The role of Lipid dropletsin metabolic disease in rodents and humans Phospholipids and Lipid droplets Perilipins, ADRP, and other proteins that associate with intracellular neutral Lipid dropletsin animal cells Isolating Lipid dropletsfrom multiple species Deformation of Lipid dropletsin fixed samples Balancing the fat: Lipid dropletsand human disease Lipid droplets: a dynamic organelle moves into focus Regulation of Lipid dropletsby autophagy Interactomic study on interaction between Lipid dropletsand mitochondria Lipid droplets: proteins floating on a pool of fat The surface of Lipid dropletsis a phosphoLipidmonolayer with a unique fatty acid composition Fluorescent detection of Lipid dropletsand associated proteins Live cell multicolor imaging of Lipid dropletswith a new dye, LD540 Nuclear Lipid droplets: a novel nuclear domain Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of Lipid droplets A role for phosphatidic acid in the formation of “supersized” Lipid droplets Coatomer-dependent protein delivery to Lipid droplets Minireview: Lipid dropletsin lipogenesis and lipolysis Nile red: a selective fluorescent stain for intracellular Lipid droplets. Structural determinants that target the hepatitis C virus core protein to Lipid droplets Proteomic analysis of proteins associated with Lipid dropletsof basal and lipolytically stimulated 3T3-L1 adipocytes Lipid dropletsinteract with mitochondria using SNAP23 Emerging roles for Lipid dropletsin immunity and host-pathogen interactions Fat on the move: intracellular motion of Lipid droplets Hepatic stellate cell Lipid droplets: a specialized Lipiddroplet for retinoid storage Triacylglycerol synthesis enzymes mediate Lipiddroplet growth by relocalizing from the ER to Lipid droplets Perilipin is located on the surface layer of intracellular Lipid dropletsin adipocytes. Influence of emulsifier type on in vitro digestibility of Lipid dropletsby pancreatic lipase Lipid droplets: FSP27 knockout enhances their sizzle Lipid dropletsand hepatitis C virus infection Fixation methods for the study of Lipid dropletsby immunofluorescence microscopy Identification of the major functional proteins of prokaryotic Lipid droplets Lipid dropletslighting up: insights from live microscopy The perilipin family of structural Lipiddroplet proteins: stabilization of Lipid dropletsand control of lipolysis The dynamic roles of intracellular Lipid droplets: from archaea to mammals FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular Lipid droplets Lipid dropletsas dynamic organelles connecting storage and efflux of lipids Emerging role of Lipid dropletsin host/pathogen interactions Network distribution of mitochondria and Lipid dropletsin human muscle fibres The emergence of
Repair of iron-induced DNA oxidation by the flavonoid myricetin in primary rat hepatocyte cultures Dietary flavonoids protect human colonocyte DNA from oxidative attack in vitro Protective effect of rutin, a flavonol glycoside, on the carcinogen-induced DNA damage and repair enzymes in rats The effect of dietary flavonoids on DNA damage (strand breaks and oxidised pyrimdines) and growth in human cells Quercetin and myricetin protect against hydrogen peroxide-induced DNA damage (strand breaks and oxidised pyrimidines) in human lymphocytes Protection from UV-B-induced DNA damage by flavonoids Basic mechanisms of antioxidant activity Hibiscus protocatechuic acid protects against oxidative damage induced by tert-butylhydroperoxide in rat primary hepatocytes Differential visualization of transparent testa mutants in Arabidopsis thaliana Cancer‐Protective Factors in Fruits and Vegetables: Biochemical and Biological Background. The biochemistry of green tea polyphenols and their potential application in human skin cancer Severe sensitivity to ultraviolet radiation in an Arabidopsis mutant deficient in flavonoid accumulation Bioactive phytochemicals with emphasis on dietary practices Higher plants and UV-B radiation: balancing damage, repair and acclimation Kaempferol-induced nuclear DNA damage and lipid peroxidation Oxygen and nitrogen are pro-carcinogens. Damage to DNA by reactive oxygen, chlorine and nitrogen species: measurement, mechanism and the effects of nutrition Quercetin prevents DNA single strand breakage and cytotoxicity caused by tert-butylhydroperoxide: free radical scavenging versus iron chelating mechanism Antioxidant and pro-oxidant actions of flavonoids : effects on DNA damage induced by nitric oxide, peroxynitrite and nitroxyl anion Effect of emodin on cooked-food mutagen activation DNA repair in higher plants Genotoxic effects of crude juices from Brassica vegetables and juices and extracts from phytopharmaceutical preparations and spices of cruciferous plants origin in … Biological effects of myricetin Arabidopsis mutants lacking phenolic sunscreens exhibit enhanced ultraviolet-B injury and oxidative damage flavonoids modulate comet assay responses to food mutagens in human lymphocytes and sperm Stimulation of bioactive flavonoid production in suspension and bioreactor-based cell cultures A review of the genetic effects of naturally occurring flavonoids , anthraquinones and related compounds Antioxidant defence mechanisms: from the beginning to the end (of the beginning) Protection by the flavonoids myricetin, quercetin, and rutin against hydrogen peroxide-induced DNA damage in Caco-2 and Hep G2 cells Mechanistic considerations in chemopreventive drug development Mechanisms of inhibitors of mutagenesis and carcinogenesis Commentary oxidative stress, nutrition and health. Experimental strategies for optimization of nutritional antioxidant intake in humans Modulating effects of flavonoids on food mutagens in human blood and sperm samples in the comet assay Plant‐derived products as antimutagens Inhibition of the induction of cancer by antioxidants Antimutagenesis and antioxidation by phenolic compounds Generation of hydrogen peroxide by “antioxidant” beverages and the effect of milk addition. Is cocoa the best beverage? Dietary modifiers of carcinogenesis. Can oxidative DNA damage be used as a biomarker of cancer risk in humans? Problems, resolutions and preliminary results from nutritional supplementation studies Natural-product inhibitors of human DNA ligase I Inhibition of 7, 12-dimethylbenz (a) anthracene-and N-nitrosomethylurea-induced rat mammary cancer by dietary flavonol quercetin Protective effects of dried flower extracts of Hibiscus sabdariffa L. against oxidative stress in rat primary hepatocytes
Studies on the effect of nicotinic acid on catecholamine stimulated lipolysis in adipose tissue in vitro. Hormone-stimulated lipolysis in isolated fat cells from “young” and “old” rats Impairment of cold-stimulated lipolysis by acute hypoxia Bimodal effect of insulin on hormone-stimulated lipolysis: relation to intracellular 3′, 5′-cyclic adenylic acid and free fatty acid levels lipolysis in chicken adipose tissue in vitro Effects of electrolytes on epinephrine stimulated lipolysis in adipose tissue in vitro Effect of vitamin D2 on hormone-stimulated lipolysis in vitro Metabolic inhibitors and catecholamine-stimulated lipolysis Role of Ca2+ in adrenocorticotropic hormone-stimulated lipolysis in the perifused fat cell system The inhibition of norepinephrine-stimulated lipolysis by acute hypoxia Digitoxin and prostaglandin ei as inhibitors of catecholamine-stimulated lipolysis and their interaction with Ca2+ in the process Endotoxin-induced alterations in isolated fat cells: Effect on norepinephrine-stimulated lipolysis and cyclic 3′, 5′-adenosine monophosphate accumulation Effect of cell size on lipolysis and antilipolytic action of insulin in human fat cells Effect of antimycin A on hormone-stimulated lipolysis in vitro Dependence of hormone-stimulated lipolysis on energy metabolism INFLUENCE OF THE HYPOTHYROID STATE ON lipolysis IN HUMAN ADIPOSE TISSUE IN VITRO: Hypothyroid State and lipolysis Effect of Nicotinic Acid on ACTH and Noradrenaline stimulated lipolysis in the Rabbit. II. In Vitro Studies Including Comparison with Prostaglandin E1 Hormonal regulation of lipolysis and phosphorylase activity in human fat cells The effect of local anaesthetic agents on lipolysis by human adipose tissue lipolysis of human adipose tissue cells: influence of donor factors The effect of dihydroergotamine on ACTH-stimulated lipolysis in rat adipocytes An abnormality of adrenaline, phentolamine stimulated lipolysis in adipose tissue from obese, maturity-onset diabetics The action of local anaesthetics on lipolysis and on adenosine 3′: 5′-cyclic monophosphate content in isolated rat fat-cells Ethanol inhibition of serum stimulated lipolysis in isolated fat cells of the rat lipolysis of genetically obese and/or hyperglycemic mice with reference to insulin response of adipose tissue Growth and lipolysis of rat adipose tissue: effect of age, body weight, and food intake Studies on lipolysis in human adipose cells The effect of human placental lactogen on adipose tissue lipolysis Diethyl chelidonate, a specific inhibitor of hormone-stimulated lipolysis lipolysis by human adipose tissue: The role of cyclic 3′, 5′-adenosine monophosphate and adrenergic receptor sites Effect of weight and cell size on hormone-induced lipolysis in New Zealand obese mice and American obese hyperglycemic micce lipolysis in vitro in adipose tissue from embryonic and growing chicks Effect of nicotinic acid on ACTH and noradrenaline stimulated lipolysis in the rabbit. 1. In vivo studies. Transport-inducing antibiotics (Gramicidin and Valinomycin) as inhibitors of catecholamine-stimulated lipolysis in vitro Stimulation of lipolysis and calcium accumulation by parathyroid hormone in rat adipose tissue in vitro after adrenalectomy and administration of high doses of … Inhibition of lipolysis in bovine adipose tissue by butyrate and β-hydroxybutyrate The effect of local anaesthetics on lipolysis in fat-cells An in vitro effect of triiodothyronine on lipolysis, cyclic AMP-C14 accumulation and oxygen consumption in isolated fat cells lipolysis and lipogenesis from glucose in human fat cells of