• SHOP
    • COMBOS
    • TESTIMONIALS
    • CART
    • INGREDIENTS
      • 2-Deoxy-D-Glucose (2DG)
      • Acacia Cyanophylla Flower
      • Acori Graminei Rhizoma
      • Aegle Marmelos Correa
      • Agaricus Blazei
      • Aged Garlic Extract
      • Aframomum Melegueta
      • Aloe Arborescens
      • Albizia
      • Alpinia Officinarum
      • Alternanthera Sessilis
      • American Ginseng
      • Amygdalin
      • Anacyclus Pyrethrum
      • Angelica Archangelica
      • Angelica Sinensis
      • Antrodia
      • Artichoke Leaf
      • Artocarpin
      • Ajuga Turkestanica
      • Ashwagandha
      • Aspalathin
      • Astragalus Complanatus
      • Avena Sativa
      • Bacopa Monnieri
      • Bavachin
      • Bee Pollen
      • Betulinic Acid
      • Boswellic Acid
      • Brevilin A
      • Campesterol
      • Casticin
      • Chrysin
      • Cinnamomum Zeylanicum
      • Citrullus Colocynthis
      • Citrus Reticulata Peel
      • Codonopsis
      • Costunolide
      • Cucurbitacin D
      • Daidzein
      • Decursin
      • Delphinidin
      • Digitalis Purprea (Digoxin)
      • Diosmin
      • Embelin
      • Gallic Acid
      • Glycitein
      • Glycyrrhizin
      • Hyperforin
      • Icariin
      • Isorhamnetin
      • Isoorientin
      • Isovitexin
      • Jaceosidin
      • Kaempferol
      • Kurarinone
      • Lemon balm
      • Licoricidin
      • Lipoic acid
      • Lupeol
      • Magnolol
      • Mulberry Leaf
      • Naringenin
      • Nobiletin
      • Oleacein
      • Oleanolic acid
      • Oridonin
      • Parthenolide
      • Phloroglucinol
      • Piceatannol
      • Pristimerin
      • Proanthocyanidins
      • Procyanidin B3
      • Pseudolaric acid b
      • Pterostilbene
      • Rutin
      • Solidago Virgaurea
      • Tangeretin
      • Taraxasterol
      • Trichostatin A
      • Wedelolactone
      • Wogonin
      • Yerba Mate
    • ABOUT
    • SCIENTIFIC STUDIES
      • ALLERGIES & CYTOKINES
      • ANTI-ACNE EFFECT OF FLAVONOIDS AND POLYPHENOLS
      • ADVANCED GLYCATION END PRODUCTS (AGES)
      • AMPK
      • ANTI-AGING EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-APOPTOTIC PATHWAYS
      • ANTI-CANCER EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI COVID-19 EFFECTS OF FLAVONOIDS AND POLYPHENOLS (1000 SCIENTIFIC STUDIES)
      • ANTI-INFLAMMATORY EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • ANTI-VIRAL EFFECTS OF FLAVONOIDS & POLYPHENOLS
      • APOPTOSIS
      • AUTOPHAGY
      • BCL-2
      • BCL-W
      • BCL-XL
      • BECLIN-1 & AUTOPHAGY
      • BH3 MIMETICS
      • BIM aka BCL2L11
      • BMI-1
      • CARDIAC GLYCOSIDES
      • CENTENARIANS
      • CYP2E1
      • CYTOKINES IN PAIN, INFLAMMATION & AGING
      • DAF-16
      • EPIGENETIC MODIFIERS
      • FGF21
      • KLOTHO
      • FASTING, CALORIE RESTRICTION & EXTENDING LIFESPAN
      • FOXO3
      • FOXO4
      • HMGB1
      • HSP90 INHIBITORS
      • HYPERINSULINEMIA
      • IKK
      • IL-6/STAT3
      • INFECTOBESITY
      • INFLAMMATION & ANXIETY
      • INFLAMMATION & CANCER
      • INFLAMMATION & DEPRESSION
      • INFLAMMATION & OBESITY
      • INFLAMMAGING
      • INSULIN & AGING
      • JAK INHIBITION ALLEVIATES SASP
      • JNK ACTIVATION PREVENTS PREMATURE SENESCENCE
      • KETONE BODIES
      • KETOGENIC DIET
      • LIFESPAN EXTENSION
      • MATRIX METALLOPROTEINASES (MMPs)
      • MCL-1
      • MDM2 INHIBITION AS SASP INHIBITOR
      • MSG (MONOSOSODIUM GLUTAMATE)
      • MYOSTATIN INHIBITION
      • MYOSTATIN INHIBITION PRESERVES MUSCLE
      • mTOR: THE RAPID AGING PATHWAY
      • NEUROINFLAMMATION
      • NMDA & ANXIETY & DEPRESSION
      • NMDA RECEPTOR AND FEAR
      • NOOTROPICS
      • NRF2: MASTER REGULATOR OF THE AGING PROCESS
      • NF-KB
      • ONCOGENE ACTIVATION INDUCED SENESCENCE
      • OXIDATIVE STRESS & AGING
      • P16INK4A
      • P38MAPK
      • P53: TUMOR SUPRESSOR
      • PHYTOECDYSTEROIDS
      • PPARY2
      • PREMATURE SENESCENCE
      • SASP & ADIPOSE TISSUE
      • SENESCENT CELLS, SASP & SENOLYTICS
      • SENESCENCE-BETA-GALACTOSIDASE (SA-β-gal or SABG)
      • SKIN PHOTOAGING (Preventing & Repairing)
      • SIRT1 & LONGEVITY
      • SUGAR & AGING
      • STAT3
      • TELOMERE SHORTENING & PREMATURE AGING
    • HOME
    • FAQ
    • CONTACT
    • INTERSTELLAR 88/8: EXTREME WEIGHTLOSS PROTOCOL
    • The Ultimate Dry Fasting Resource
    0
    Hedyotis Diffusa Willd
    September 17, 2018
    Lactarius Flavidulus
    September 17, 2018

    Hericium Erinaceus

    Hericium Erinaceus or more commonly known as Lion's Mane Mushroom is known as a nootropic that is capable of improving one’s cognitive ability.



    It is also known as Hou To Gu or the Bearded Tooth Fungus and has been used in many Asian countries as a type of culinary and medicinal uses. When cooked or eaten raw it has been said to have a similar taste to that of sea food. This mushroom contains many bioactive compounds that has amazing effects on our body and brain.

    Benefits of Hericium Erinaceus

    Anti-Tumor - We investigated antitumor effects of the following four extracts of freeze-dried Hericium erinaceus mushrooms in Balb/c mice intracutaneously transplanted on the backs with CT-26 colon cancer cells.

    Daily intraperitoneal (ip) injections of HWE and MWE for 2 weeks significantly reduced tumor weights by 38 and 41%

    Reduced COX-2 and 5-LOX expression down-regulated VEGF expression, resulting in inhibition of neo-angiogenesis inside the tumors. The results indicate that induction of NK activity, activation of macrophages, and inhibition of angiogenesis all contribute to the mechanism of reduction of tumor size.

    (Article)

    In this study, Hericium erinaceus and Hericium laciniatum were separately cultivated in a shaker at 25 degrees C for 25 days.

    The results revealed that both polysaccharides had significant anti-artificial pulmonary metastatic tumor effects in mice (p < 0.05).

    (Article)

    Apoptosis - It has been demonstrated that the Hericium erinaceus (HE) mushroom, which primarily consists of polysaccharides, possesses anti-tumor activities.

    Our study demonstrates that HE acts as an enhancer to sensitize doxorubicin (Dox)-mediated apoptotic signaling.

    These findings suggest that HE in combination with Dox serves as an effective tool for treating drug-resistant human hepatocellular carcinoma.

    (Article)

    In the present study, we evaluated hot water (HWE), microwaved 50% ethanol (MWE), acidic (ACE), and alkaline (AKE) extracts of the fruitbody (sporocarp) of Hericium erinaceus (Yamabushitake, Lion's Mane) mushrooms for their ability to induce apoptosis (programmed cell death