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    February 28, 2019
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    February 28, 2019

    Baicalein

    Baicalein is a type of flavonoid which inhibits pro-inflammatory metabolites. It is extracted from the roots of the Scutellaria baicalensis and Scutellaria lateriflora.


    What are flavonoids? In plants it is the protective tissue that shields it from UV radiation and acts as an antioxidant. It also provides the pigment and is known to be responsible for the many autumn colors that you can find in leaves and flowers.

    In some experiments it has been shown that flavonoids are a beneficial part of the heart and circulatory system and can be used to assist with stress in your environment.

    Benefits of Baicalein

    Neuroprotective - The neuroprotective effects of baicalin on pathological changes and behavioral deficits were explored in a mouse model of amyloid β (Aβ)(1-42) protein-induced Alzheimer's disease (AD).

    The therapeutic effects of baicalin were monitored by Morris water maze trial and probe test. Then mice were sacrificed for immunohistochemistry and western blot analysis.

    These results suggest that baicalin ameliorated Aβ(1-42) protein-related pathology and cognitive dysfunction via its anti-neuroinflammatory activity, and may be a potential candidate for the treatment of AD.

    (Article)

    Anti-Anxiety - The present study further expanded the behavioral pharmacology profile of baicalin and subtype selectivity was explored as a possible mechanism underlying its in vivo effects on mice. Baicalin was characterized using convulsion, memory, and motor function related animal tests.

    Its subtype selectivity suggested that baicalin exerted its in vivo anxiolytic-like effect mainly through the α2- and α3-containing subtypes. Therefore, the present study revealed an underlying mechanism for the selective anxiolytic profile of baicalin, suggesting α2- and α3-containing subtypes were important drug targets for flavonoid-based anxiolytics.

    (Article)

    Antioxidant -In this study, their antioxidant activity was evaluated by modified xanthine oxidase inhibition and cytochrome c reduced methods. The results showed that the order of activity on xanthine oxidase inhibition was baicalein > wogonin > baicalin.

    The present results demonstrated that baicalein and baicalin posed a different pathological pathway. The antioxidant function of baicalin was mainly based on scavenging superoxide radical whilst baicalein was a good xanthine oxidase inhibitor.

    (Article)

    Vision Health - This review focuses on the main flavones baicalein, baicalin, and wogonin isolated from the Chinese medicinal herb, Scutellariae radix (SR), which has been widely used in Asian countries for the treatment of many diseases.

    Interest in SR has grown recently following new findings that suggest multiple routes of therapeutic action.

    This review will summarize the diverse pharmacological properties, therapeutic roles, and mechanisms of these flavones of SR in cellular and animal models of ocular diseases.

    (Article)

    Anti-Cancer - The aim of the study is to explore the efficiency of combination therapy with baicalein and taxol, as well as the molecular mechanism on antitumor activity. Human ovarian cancer cells were treated with different concentration of baicalein for 48 h, and cell viability was determined by MTT assay.

    The ovarian cancer cells were treated with 10 μM of baicalein combined with increasing concentration of taxol for 48 h, and the results demonstrated that combination therapy with baicalein and taxol had much higher antitumor effects compared with the monotherapy.

    Furthermore, baicalein induced apoptosis through activation of the activities of caspase-3,-9, and increased cytoplasmic cytochrome C release.

    Baicalein has a promising potential to be developed as an antitumor compound, and combination therapy of baicalein and taxol exhibits an antitumor potential in clinical therapy for human ovarian cancers.

    (Article)

    In this next study,they observed that baicalin can be quickly converted to baicalein. We compared the antiproliferative effects of baicalin and baicalein using a panel of human cancer cell lines, including three human colorectal cancer (CRC) cell lines. In vitro antiproliferative effects on CRC cells were verified using an in vivo xenograft nude mouse model.

    Data from this study suggested that baicalein is a potent anticancer metabolite derived from S. baicalensis. Enteric microbiota play a key role in the colon cancer chemoprevention of S. baicalensis.

    (Article)

    Liver Disease - In the present study, it shows that Baicalein was able to reduce the effects of fatty liver disease beacause it increased the PPAR Gamma and insulin recptors. A rat model of NAFLD, induced by a high-fat diet, was established and orthographical experimentation was used to investigate the effects of various combinations of puerarin, baicalin and berberine on the hepatic expression of proliferator-activated receptor (PPAR)-γ and insulin receptor (IR).

    In conclusion, a combination of puerarin, baicalin and berberine induced favorable effects on NAFLD by upregulating hepatic PPAR-γ and IR expression levels, and different proportions of monomer compositions exerted variable positive effects on various stages of NAFLD.

    (Article)

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    SEVEN SAGES

    1. A 1: 1 Cocrystal Of Baicalein With Nicotinamide
    2. A Bioinformatic Approach For The Discovery Of Antiaging Effects Of Baicalein From Scutellaria Baicalensis Georgi
    3. A Catenary Model To Study Transport And Conjugation Of Baicalein, A Bioactive Flavonoid, In The Caco-2 Cell Monolayer: Demonstration Of Substrate Inhibition
    4. A Combination Therapy With Baicalein And Taxol Promotes Mitochondria-Mediated Cell Apoptosis: Involving In Akt/Β-Catenin Signaling Pathway
    5. A Comparative Study Of Baicalein And Chlorhexidine Mouthrinses On The Oral Health Of Physically Disabled Patients
    6. A Comparative Study Of The Anti-Allergic Effects Of Disodium Baicalein 6-Phosphate (Bps) And Disodium Cromoglycate (Dscg)
    7. A Convenient Method For The Synthesis Of Baicalein (5, 6, 7-Trihydroxyflavone) And 4′-Methylgamatin (4-Methoxy-3-Methyl-7-Phenylfuro-[3, 2-G][1] Benzopyran-5-One)
    8. A Joint Application Of Vibrational Spectroscopic And Quantum Mechanical Methods In Quantitative Analysis Of Baicalein Structure
    9. A Nano-Cocrystal Strategy To Improve The Dissolution Rate And Oral Bioavailability Of Baicalein
    10. A New 1, 2, 3, 4-Tetrahydroquinoxaline Derivative Combining Baicalein And 1, 2-Diphenylethylenediamine Moieties: Structure And Its Fluorescence-Based Detection Of …
    11. A New Validated Simultaneous Reversed-Phase High-Performance Liquid Chromatography Assay Method For Estimation Of Two Flavones (Baicalein And Chrysin) In …
    12. A Notch1-Regulated Lncrna, Ak022798, Contributes To The Baicalein-Induced Apoptosis In Hepatocellular Carcinoma
    13. A Novel Anti-Fibrotic Agent, Baicalein, For The Treatment Of Myocardial Fibrosis In Spontaneously Hypertensive Rats
    14. A Novel Electrochemical Sensor For Detection Of Baicalein In Human Serum Based On Dut‐9/Mesoporous Carbon Composite
    15. A Novel Inhibitory Mechanism Of Baicalein On Influenza A/Fm1/1/47 (H1N1) Virus: Interference With Mid-Late Mrna Synthesis In Cell Culture
    16. A Novel Matrix Dispersion Based On Phospholipid Complex For Improving Oral Bioavailability Of Baicalein: Preparation, In Vitro And In Vivo Evaluations
    17. A Novel Molecularly Imprinted Method With Computational Simulation For The Affinity Isolation And Knockout Of Baicalein From Scutellaria Baicalensis
    18. A Strategy To Improve The Oral Availability Of Baicalein: The Baicalein-Theophylline Cocrystal
    19. A Synopsis On Flavonoids From The Roots Of Scutellaria Baicalensis With Some Insights On Baicalein And Its Anti-Cancer Properties
    20. A Voltammetry Sensor Platform For Baicalein And Baicalin Simultaneous Detection In Vivo Based On Ta2O5-Nb2O5@ Cts Composite
    21. Abstract P125: Baicalein Preconditioning Protects Murine Cardiomyocytes From Ischemia/Reperfusion Injury Via Mitochondrial Oxidant And Akt Signaling
    22. Abstract# 2701: Effects Of Paeoniflorin, Baicalein, Hesperidin And Oleanolic Acid On Human Breast And Prostate Cancer Cells
    23. Activation Of The Nrf2/Ho-1 Signaling Pathway Contributes To The Protective Effects Of Baicalein Against Oxidative Stress-Induced Dna Damage And Apoptosis In …
    24. Acute Toxicity Test Of Baicalein Capsule In Mice
    25. Adsorption Chromatography Separation Of Baicalein And Baicalin Using Collagen Fiber Adsorbent
    26. Advances In Study On Baicalein For Regulation Of Signaling Pathways In Myocardial Ischemia/Hypoxia
    27. Afm And Fluorescence Spectrascopy Investigation For Disaggregation Of Existing Aβ Fibrils By Baicalein
    28. Amelioration Of Ionizing Radiation Induced Cell Death In Lymphocytes Redox Reaction By Baicalein
    29. Ameliorative Effects Of Baicalein In Mptp-Induced Mouse Model Of Parkinson’S Disease: A Microarray Study
    30. Ameliorative Effects Of Baicalein On An Amyloid-Β Induced Alzheimer’S Disease Rat Model: A Proteomics Study
    31. Amination, A Newly Discovered Metabolic Pathway Of Myricetin And Baicalein
    32. Amylin Amyloid Inhibition By Flavonoid Baicalein: Key Roles Of Its Vicinal Dihydroxyl Groups Of The Catechol Moiety
    33. An Agent-Based Approach To Dynamically Represent The Pharmacokinetic Properties Of Baicalein
    34. An Enhanced Preparation And Purification Of The Major Antioxidants Baicalein And Wogonin From Scutellariae Radix
    35. An Improved Drugs Screening System Reveals That Baicalein Ameliorates The Aβ/Ampa/Nmda-Induced Depolarization Of Neurons
    36. Analgesia Effect Of Baicalein Against Ntg-Induced Migraine In Rats
    37. Analysis And Comparison Of Baicalin, Baicalein And Wogonin Contents In Traditional Decoctions And Commercial Extracts Of Scutellariae Radix
    38. Analysis Of Baicalein, Baicalin And Wogonin In Scutellariae Radix And Its Preparation By Microemulsion Electrokinetic Chromatography With 1-Butyl-3-Methylimizolium …
    39. Analysis Of Inhibitory Effects Of Scutellariae Radix And Baicalein On Prostaglandin E2 Production In Rat C6 Glioma Cells
    40. Antagonism Of Saikosaponin-Induced Prostaglandin E2 Release By Baicalein In C6 Rat Glioma Cells
    41. Anti-Angiogenic And Anticancer Effects Of Baicalein Derivatives Based On Transgenic Zebrafish Model
    42. Anti-Arthritic Effect Of Baicalein Exert On Complete Freund’S Adjuvant-Induced Arthritis In Rats By Reducing The Inflammatory Reaction
    43. Antibacterial Activity And Mechanism Of Baicalein
    44. Anti-Bladder-Tumor Effect Of Baicalein From Scutellaria Baicalensis Georgi And Its Application In Vivo
    45. Anticancer Activity And Modulation Of Protein And Gene Expression By Baicalein Loaded Iron Oxide Nano Conjugates In Triple Negative Breast Cancer Cells
    46. Anticancer Activity Of Baicalein And Luteolin Studied In Colorectal Adenocarcinoma Lovo Cells And In Drug-Resistant Lovo/Dx Cells
    47. Anticancer Effects Of Baicalein In Fro Thyroid Cancer Cells Through The Up-Regulation Of Erk/P38 Mapk And Akt Pathway
    48. Anti-Cancer Effects Of Baicalein In Non-Small Cell Lung Cancer In-Vitro And In-Vivo
    49. Anticancer Effects Of Baicalein In Pancreatic Neuroendocrine Tumors In Vitro And In Vivo
    50. Anticancer Effects Of Baicalein On Hepatocellular Carcinoma Cells
    51. Anticancer Properties Of Baicalein: A Review
    52. Anticancer, Antiradical And Antioxidative Actions Of Novel Antoksyd S And Its Major Components, Baicalin And Baicalein.
    53. Antidepressant Effects Of A Plant-Derived Flavonoid Baicalein Involving Extracellular Signal-Regulated Kinases Cascade
    54. Anti-Diabetic Effect Of Baicalein Is Associated With The Modulation Of Gut Microbiota In Streptozotocin And High-Fat-Diet Induced Diabetic Rats
    55. Anti-Fibrillation Propensity Of A Flavonoid Baicalein Against The Fibrils Of Hen Egg White Lysozyme: Potential Therapeutics For Lysozyme Amyloidosis
    56. Antifibrotic Effects Of Chronic Baicalein Administration In A Ccl4 Liver Fibrosis Model In Rats
    57. Antifungal Activity Of Baicalein Against Candidakrusei Does Not Involve Apoptosis
    58. Anti-Inflammatory Activity Of Baicalein In Lps-Stimulated Raw264.7 Macrophages Via Estrogen Receptor And Nf-Κb-Dependent Pathways
    59. Anti-Inflammatory Effect Of A New Formulation: Palmitoylethanolamide/Baicalein In A Murine Model Of Myocardial Ischaemia/Reperfusion Injury
    60. Anti-Inflammatory Effect Of Baicalein On Polyinosinic–Polycytidylic Acid-Induced Raw 264.7 Mouse Macrophages
    61. Anti-Inflammatory Effects Of Baicalin, Baicalein, And Wogonin In Vitro And In Vivo
    62. Anti-Inflammatory Properties And Inhibition Of Leukotriene C4 Biosynthesisin Vitro By Flavonoid Baicalein Fromscutellaria Baicalensis Georgy Roots
    63. Antineoplastic Baicalein And Baicalin Synergistic Pharmaceutical Composition
    64. Antioxidant And Free Radical Scavenging Effects Of Baicalein, Baicalin And Wogonin.
    65. Antiproliferative Effect Of Baicalein, A Flavonoid From A Chinese Herb, On Vascular Smooth Muscle Cell
    66. Anti-Pruritic Effect Of Baicalin And Its Metabolites, Baicalein And Oroxylin A, In Mice
    67. Antitumor Actions Of Baicalein And Wogonin In Ht-29 Human Colorectal Cancer Cells
    68. Antitumor Activity Of Baicalein On The Mice Bearing U14 Cervical Cancer
    69. Anti-Tumor Effects Of Baicalein On H22 Hepatocarcinoma-Bearing Mice
    70. Antitumor Effects Of Saikosaponins, Baicalin And Baicalein On Human Hepatoma Cell Lines
    71. Antitumor Effects Of Scutellariae Radix And Its Components Baicalein, Baicalin, And Wogonin On Bladder Cancer Cell Lines
    72. Antiviral Activity Of Baicalein And Quercetin Against The Japanese Encephalitis Virus
    73. Antiviral Effects Of Baicalein On Human Cytomegalovirus In Vitro
    74. Anxiolytic-Like Effects Of Baicalein And Baicalin In The Vogel Conflict Test In Mice
    75. Application Of Carrier And Plasticizer To Improve The Dissolution And Bioavailability Of Poorly Water-Soluble Baicalein By Hot Melt Extrusion
    76. Application Of Ftir Microspectroscopy For Monitoring And Discrimination Of The Anti-Adipogenesis Activity Of Baicalein In 3T3-L1 Adipocytes
    77. Application Of Soluplus To Improve The Flowability And Dissolution Of Baicalein Phospholipid Complex
    78. Ask1/Jnk-Mediated Tap63 Activation Controls The Cell Survival Signal Of Baicalein-Treated Ebv-Transformed B Cells
    79. Aspergillus Fumigatus Dbm 4057 Biofilm Formation Is Inhibited By Chitosan, In Contrast To Baicalein And Rhamnolipid
    80. Assessment Of The Treatment Effect Of Baicalein On A Model Of Parkinsonian Tremor And Elucidation Of The Mechanism
    81. Astragalus And Baicalein Regulate Inflammation Of Mesenchymal Stem Cells (Mscs) By The Mitogen-Activated Protein Kinase (Mapk)/Erk Pathway
    82. Attenuation Of Neurological Injury With Early Baicalein Treatment Following Subarachnoid Hemorrhage In Rats
    83. Attenuation Of Oxidative Stress In Hek 293 Cells By The Tcm Constituents Schisanhenol, Baicalein, Resveratrol Or Crocetin And Two Defined Mixtures
    84. Au-Pt@ Biomass Porous Carbon Composite Modified Electrode For Sensitive Electrochemical Detection Of Baicalein
    85. Author Correction: Structure-Activity Relationships Of Baicalein And Its Analogs As Novel Tslp Inhibitors
    86. Baicalein (5, 6, 7-Trihydroxyflavone) Reduces Oxidative Stress-Induced Dna Damage By Upregulating The Dna Repair System
    87. Baicalein 5, 6, 7-Trimethyl Ether Activates Peroxisomal But Not Mitochondrial Fatty Acid Β-Oxidation
    88. Baicalein 5, 6, 7‐Trimethyl Ether, A Flavonoid Derivative, Stimulates Fatty Acid Β‐Oxidation In Skin Fibroblasts Of X‐Linked Adrenoleukodystrophy
    89. Baicalein 6-Methy Ether 7-Glucoside Induced Apoptosis In Hela Cells Via Caspase Dependent Pathway
    90. Baicalein 6-O-Β-D-Glucopyranuronoside Is A Main Metabolite In The Plasma After Oral Administration Of Baicalin, A Flavone Glucuronide Of Scutellariae Radix, To Rats
    91. Baicalein 7-O-Glucuronosyltransferase 2.4. 1.253
    92. Baicalein Abrogates Reactive Oxygen Species (Ros)‐Mediated Mitochondrial Dysfunction During Experimental Pulmonary Carcinogenesis In Vivo
    93. Baicalein Accelerates Tendon-Bone Healing Via Activation Of Wnt/Β-Catenin Signaling Pathway In Rats
    94. Baicalein Activates Aryl Hydrocarbon Receptor And Decreases The Expression Of Cdk4 And Cyclin D1 To Induce G1 Phase Arrest In Oral Cancer Cells
    95. Baicalein Acts As A Nephroprotectant That Ameliorates Colistin-Induced Nephrotoxicity By Activating The Antioxidant Defence Mechanism Of The Kidneys And Down …
    96. Baicalein Administered In The Subacute Phase Ameliorates Ischemia-Reperfusion-Induced Brain Injury By Reducing Neuroinflammation And Neuronal Damage
    97. Baicalein Administration Protects Against Pentylenetetrazole-Induced Chronic Epilepsy In Rats
    98. Baicalein Alleviates Diabetic Peripheral Neuropathy Through Inhibition Of Oxidative–Nitrosative Stress And P38 Mapk Activation
    99. Baicalein Alleviates Doxorubicin-Induced Cardiotoxicity Via Suppression Of Myocardial Oxidative Stress And Apoptosis In Mice
    100. Baicalein Alleviates Liver Oxidative Stress And Apoptosis Induced By High-Level Glucose Through The Activation Of The Perk/Nrf2 Signaling Pathway
    101. Baicalein Alleviates Tubular-Interstitial Nephritis In Vivo And In Vitro By Down-Regulating Nf-Κb And Mapk Pathways
    102. Baicalein Alters Pi3K/Akt/Gsk3Β Signaling Pathway In Rats With Diabetes-Associated Cognitive Deficits
    103. Baicalein Ameliorated The Upregulation Of Striatal Glutamatergic Transmission In The Mice Model Of Parkinson’S Disease
    104. Baicalein Ameliorates Cadmium-Induced Hepatic And Renal Oxidative Damage In Rats
    105. Baicalein Ameliorates Chronic Stress-Mediated Ovarian Dysfunction By Upregulating The Expression Of Gamma-Aminobutyric Acid B2 Receptor
    106. Baicalein Ameliorates Cognitive Deficits In Epilepsy-Like Tremor Rat
    107. Baicalein Ameliorates Inflammatory-Related Apoptotic And Catabolic Phenotypes In Human Chondrocytes
    108. Baicalein Ameliorates Pristane-Induced Lupus Nephritis Via Activating Nrf2/Ho-1 In Myeloid-Derived Suppressor Cells
    109. Baicalein Ameliorates Pulmonary Arterial Hypertension Caused By Monocrotaline Through Downregulation Of Et-1 And Etar In Pneumonectomized Rats
    110. Baicalein Ameliorates Renal Interstitial Fibrosis By Inducing Myofibroblast Apoptosis In Vivo And In Vitro
    111. Baicalein Ameliorates Tnbs-Induced Colitis By Suppressing Tlr4/Myd88 Signaling Cascade And Nlrp3 Inflammasome Activation In Mice
    112. Baicalein And 12/15-Lipoxygenase In The Ischemic Brain
    113. Baicalein And Baicalin Alleviate Acetaminophen-Induced Liver Injury By Activating Nrf2 Antioxidative Pathway: The Involvement Of Erk1/2 And Pkc
    114. Baicalein And Baicalin Are Potent Inhibitors Of Angiogenesis: Inhibition Of Endothelial Cell Proliferation, Migration And Differentiation
    115. Baicalein And Baicalin As Zika Virus Inhibitors
    116. Baicalein And Baicalin Inhibit Colon Cancer Using Two Distinct Fashions Of Apoptosis And Senescence
    117. Baicalein And Baicalin Promote Antitumor Immunity By Suppressing Pd-L1 Expression In Hepatocellular Carcinoma Cells
    118. Baicalein And Genistein Display Differential Actions On Estrogen Receptor (Er) Transactivation And Apoptosis In Mcf-7 Cells
    119. Baicalein And Hydroxypropyl-Γ-Cyclodextrin Complex In Poloxamer Thermal Sensitive Hydrogel For Vaginal Administration
    120. Baicalein And Its Underlying Mechanism As A Protector Against Liver Injury Induced By Cisplatin In Mice
    121. Baicalein And Ly294002 Induces Liver Cancer Cells Apoptosis Via Regulating Phosphatidyl Inositol 3-Kinase/Akt Signaling Pathway
    122. Baicalein And Meformin Decrease Small Cell Lung Cancer Growth By Inhibiting The Mtor Pathway In Itro
    123. Baicalein And U0126 Suppress Bladder Cancer Proliferation Via Mapk Signaling Pathway
    124. Baicalein And U0126 Suppress Human Breast Cancer Cell Line Mcf-7 Through Regulating Mapk Signaling Pathway
    125. Baicalein And Wogonin Are Activators Of Rat Trek‐2 Two‐Pore Domain K+ Channel
    126. Baicalein Antagonizes Acute Megakaryoblastic Leukemia In Vitro And In Vivo By Inducing Cell Cycle Arrest
    127. Baicalein Antagonizes Rotenone-Induced Apoptosis In Dopaminergic Sh-Sy5Y Cells Related To Parkinsonism
    128. Baicalein As A Potent Neuroprotective Agent: A Review
    129. Baicalein As A Potential Inhibitor Against Bace1 And Ache: Mechanistic Comprehension Through In Vitro And Computational Approaches
    130. Baicalein Attenuates 6-Hydroxydopamine-Induced Neurotoxicity In Sh-Sy5Y Cells
    131. Baicalein Attenuates Acute Lung Injury Induced By Intestinal Ischemia/Reperfusion Via Inhibition Of Nuclear Factor-Κb Pathway In Mice
    132. Baicalein Attenuates Angiotensin Ii-Induced Cardiac Remodeling Via Inhibition Of Akt/Mtor, Erk1/2, Nf-Κb, And Calcineurin Signaling Pathways In Mice
    133. Baicalein Attenuates Astroglial Activation In The 1‐Methyl‐4‐Phenyl‐1, 2, 3, 4‐Tetrahydropyridine‐Induced Parkinson’S Disease Model By Downregulating The …
    134. Baicalein Attenuates Bleomycin-Induced Pulmonary Fibrosis In Rats Through Inhibition Of Mir-21
    135. Baicalein Attenuates Hypertrophic Scar Formation Via Inhibition Of The Transforming Growth Factor‐Β/Smad2/3 Signalling Pathway
    136. Baicalein Attenuates Impaired Hippocampal Neurogenesis And The Neurocognitive Deficits Induced By Γ‐Ray Radiation
    137. Baicalein Attenuates Impairment Of Hepatic Lysosomal Acidification Induced By High Fat Diet Via Maintaining V-Atpase Assembly
    138. Baicalein Attenuates Inflammatory Responses By Suppressing Tlr4 Mediated Nf-Κb And Mapk Signaling Pathways In Lps-Induced Mastitis In Mice
    139. Baicalein Attenuates Intimal Hyperplasia After Rat Carotid Balloon Injury Through Arresting Cell-Cycle Progression And Inhibiting Erk, Akt, And Nf-Κb Activity In Vascular …
    140. Baicalein Attenuates Lung Injury Induced By Myocardial Ischemia And Reperfusion
    141. Baicalein Attenuates Methamphetamine-Induced Loss Of Dopamine Transporter In Mouse Striatum
    142. Baicalein Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension By Inhibiting Endothelial-To-Mesenchymal Transition
    143. Baicalein Attenuates Monocrotaline-Induced Pulmonary Arterial Hypertension By Inhibiting Vascular Remodeling In Rats
    144. Baicalein Attenuates Neurological Deficits And Preserves Blood–Brain Barrier Integrity In A Rat Model Of Intracerebral Hemorrhage
    145. Baicalein Attenuates Neuropathic Pain And Improves Sciatic Nerve Function Recovery In Rats With Partial Sciatic Nerve Transection
    146. Baicalein Attenuates Ova-Induced Allergic Airway Inflammation Through The Inhibition Of The Nf-Κb Signaling Pathway
    147. Baicalein Attenuates Oxidant Stress In Cardiomyocytes
    148. Baicalein Attenuates Oxidative Stress-Induced Expression Of Matrix Metalloproteinase-1 By Regulating The Erk/Jnk/Ap-1 Pathway In Human Keratinocytes
    149. Baicalein Attenuates Oxldl-Induced Oxidative Functional Damages In Endothelial Cells
    150. Baicalein Attenuates Pancreatic Inflammatory Injury Through Regulating Mapk, Stat 3 And Nf-Κb Activation
    151. Baicalein Attenuates Proteasome Inhibition-Induced Apoptosis By Suppressing The Activation Of The Mitochondrial Pathway And The Caspase-8-And Bid-Dependent …
    152. Baicalein Attenuates Radiation-Induced Enteritis By Improving Endothelial Dysfunction
    153. Baicalein Attenuates Renal Fibrosis By Inhibiting Inflammation Via Down-Regulating Nf-Κb And Mapk Signal Pathways
    154. Baicalein Attenuates The Neuroinflammation In Lps-Activated Bv-2 Microglial Cells Through Suppression Of Pro-Inflammatory Cytokines, Cox2/Nf-Κb Expressions And …
    155. Baicalein Attenuates The Quorum Sensing-Controlled Virulence Factors Of Pseudomonas Aeruginosa And Relieves The Inflammatory Response In P. Aeruginosa …
    156. Baicalein Attenuates Vinorelbine-Induced Vascular Endothelial Cell Injury And Chemotherapeutic Phlebitis In Rabbits
    157. Baicalein Attenuates Α-Synuclein Aggregation, Inflammasome Activation And Autophagy In The Mpp+-Treated Nigrostriatal Dopaminergic System In Vivo
    158. Baicalein Blocked Cervical Carcinoma Cell Proliferation By Targeting Ccnd1 Via Wnt/Β-Catenin Signaling Pathway
    159. Baicalein Blocks Α-Synuclein Secretion From Sn4741 Cells And Facilitates Α-Synuclein Polymerization To Big Complex
    160. Baicalein Cardioprotection Via Oxidant Scavenging And Akt-Nitric Oxide Signaling: Identification Of Early Reperfusion Phase As The Critical Therapeutic Window
    161. Baicalein Combined With Dexamethasone Can Induce The Marked Pparß-Mediated Suppression Of Growth And Survival In Human Myeloma Cells.
    162. Baicalein Decreases Hydrogen Peroxide‐Induced Damage To Ng108‐15 Cells Via Upregulation Of Nrf2
    163. Baicalein Decreases Side Population Proportion Via Inhibition Of Abcg2 In Multiple Myeloma Cell Line Rpmi 8226 In Vitro
    164. Baicalein Decreases Uric Acid And Prevents Hyperuricemic Nephropathy In Mice
    165. Baicalein Disturbs The Morphological Plasticity And Motility Of Breast Adenocarcinoma Cells Depending On The Tumor Microenvironment
    166. Baicalein Enhances Cisplatin Cytotoxicity Via Increasing Gap Junction Intercellular Communication In Cx32 Transfected Hela Cells
    167. Baicalein Enhances Migration And Invasion Of Extravillous Trophoblasts Via Activation Of The Nf-Κb Pathway
    168. Baicalein Enhances The Antitumor Efficacy Of Docetaxel On Nonsmall Cell Lung Cancer In A Β‐Catenin‐Dependent Manner
    169. Baicalein Enhances The Effect Of Low Dose Levodopa On The Gait Deficits And Protects Dopaminergic Neurons In Experimental Parkinsonism
    170. Baicalein Enhances The Gap Junction In The Tm4 Sertoli Cells Of Mice
    171. Baicalein Enhances The Oral Bioavailability And Hepatoprotective Effects Of Silybin Through The Inhibition Of Efflux Transporters Bcrp And Mrp2
    172. Baicalein Enhances The Osteogenic Differentiation Of Human Periodontal Ligament Cells By Activating The Wnt/Β-Catenin Signaling Pathway
    173. Baicalein Exerts A Protective Role In Pneumonia Caused By Streptococcus Pneumoniae.
    174. Baicalein Exerts Anticancer Effect In Nasopharyngeal Carcinoma In Vitro And In Vivo
    175. Baicalein Exerts Anti-Neuroinflammatory Effects To Protect Against Rotenone-Induced Brain Injury In Rats
    176. Baicalein Exerts Beneficial Effects In D-Galactose-Induced Aging Rats Through Attenuation Of Inflammation And Metabolic Dysfunction
    177. Baicalein Exerts Neuroprotective Effects In 6-Hydroxydopamine Induced Experimental Parkisonism (Lb625)
    178. Baicalein Exerts Neuroprotective Effects In 6-Hydroxydopamine-Induced Experimental Parkinsonism In Vivo And In Vitro
    179. Baicalein Exerts Neuroprotective Effects In Fecl3-Induced Post-Traumatic Epileptic Seizures Via Suppressing Ferroptosis
    180. Baicalein Exhibits Anti-Inflammatory Effects Via Inhibition Of Nf-Κb Transactivation
    181. Baicalein Exhibits Inhibitory Effect On The Energy-Dependent Efflux Pump Activity In Non-Albicans Candida Fungi
    182. Baicalein Has Protective Effects On The 17Β-Estradiol-Induced Transformation Of Breast Epithelial Cells
    183. Baicalein Impairs Vascular Tone In Normal Rat Aortas: Role Of Superoxide Anions
    184. Baicalein Improves Antioxidant Status And Membrane-Bound Enzymes During Oxidative Stress In Benzo (A) Pyrene-Induced Lung Carcinogenesis In Mice
    185. Baicalein Improves Behavioral Dysfunction Induced By Alzheimer’S Disease In Rats
    186. Baicalein Improves Cognitive Deficits And Hippocampus Impairments In Temporal Lobe Epilepsy Rats
    187. Baicalein Improves Cognitive Deficits Induced By Chronic Cerebral Hypoperfusion In Rats
    188. Baicalein Improves Glucose Metabolism In Insulin Resistant Hepg2 Cells
    189. Baicalein Improves Insulin Resistance Via Regulating Socs3 And Enhances The Effect Of Acarbose On Diabetes Prevention
    190. Baicalein Improves Liver Inflammation In Diabetic Db/Db Mice By Regulating Hmgb1/Tlr4/Nf-Κb Signaling Pathway
    191. Baicalein Improves Sepsis-Associated Encephalopathy Via Suppressing Oxidative Stress And Inos-Mediated No Production And Enhancing Bdnf/Trkb …
    192. Baicalein Increases Cisplatin Sensitivity Of A549 Lung Adenocarcinoma Cells Via Pi3K/Akt/Nf-Κb Pathway
    193. Baicalein Increases Keratin 1 And 10 Expression In Hacat Keratinocytes Via Trpv 4 Receptor Activation
    194. Baicalein Increases The Cytotoxicity Of Cisplatin By Enhancing Gap Junction Intercellular Communication
    195. Baicalein Increases The Expression And Reciprocal Interplay Of Runx3 And Foxo3A Through Crosstalk Of Ampkα And Mek/Erk1/2 Signaling Pathways In …
    196. Baicalein Induced Apoptosis And Autophagy Of Undifferentiated Thyroid Cancer Cells By The Erk/Pi3K/Akt Pathway
    197. Baicalein Induced Cell Apoptosis Of Human Hepatoma Cell Line Hepg2 May Be Via Mir-34A [J]
    198. Baicalein Induced Cell Cycle Arrest And Apoptosis In Human Lung Squamous Carcinoma Ch27 Cells
    199. Baicalein Induced In Vitro Apoptosis Undergo Caspases Activity In Human Promyelocytic Leukemia Hl-60 Cells
    200. Baicalein Induces A Dual Growth Arrest By Modulating Multiple Cell Cycle Regulatory Molecules
    201. Baicalein Induces Apoptosis And Autophagy Of Breast Cancer Cells Via Inhibiting Pi3K/Akt Pathway In Vivo And Vitro
    202. Baicalein Induces Apoptosis And Autophagy Via Endoplasmic Reticulum Stress In Hepatocellular Carcinoma Cells
    203. Baicalein Induces Apoptosis And Reduces Inflammation In Lps-Stimulated Keratinocytes By Blocking The Activation Of Nf-Κb: Implications For Alleviating Oral Lichen …
    204. Baicalein Induces Apoptosis In Esophageal Squamous Cell Carcinoma Cells Through Modulation Of The Pi3K/Akt Pathway
    205. Baicalein Induces Apoptosis In Scc-4 Human Tongue Cancer Cells Via A Ca2+-Dependent Mitochondrial Pathway
    206. Baicalein Induces Apoptosis Of Human Cervical Cancer Hela Cells In Vitro
    207. Baicalein Induces Apoptosis Through Ros-Mediated Mitochondrial Dysfunction Pathway In Hl-60 Cells.
    208. Baicalein Induces Apoptosis Via A Mitochondrial-Dependent Caspase Activation Pathway In T24 Bladder Cancer Cells
    209. Baicalein Induces Apoptosis Via Ros-Dependent Activation Of Caspases In Human Bladder Cancer 5637 Cells
    210. Baicalein Induces Autophagic Cell Death Through Ampk/Ulk1 Activation And Downregulation Of M Torc 1 Complex Components In Human Cancer Cells
    211. Baicalein Induces Autophagy And Apoptosis Through Ampk Pathway In Human Glioma Cells
    212. Baicalein Induces Beclin 1-And Extracellular Signal-Regulated Kinase-Dependent Autophagy In Ovarian Cancer Cells
    213. Baicalein Induces Cancer Cell Death And Proliferation Retardation By The Inhibition Of Cdc2 Kinase And Survivin Associated With Opposite Role Of P38 Mitogen-Activated …
    214. Baicalein Induces Caspase‐Dependent Apoptosis Associated With The Generation Of Ros And The Activation Of Ampk In Human Lung Carcinoma A549 Cells
    215. Baicalein Induces Caspase-Dependent Apoptosis In Human Melanoma A375 Cells Associated With Elicitation Of Extrinsic Apoptotic Pathway And Upregulation Of …
    216. Baicalein Induces Caspase-Dependent Apoptosis In Human Melanoma A375 Cells Associated With Elicitation Of Intrinsic And Extrinsic Apoptotic Pathways
    217. Baicalein Induces Cd4+ Foxp3+ T Cells And Enhances Intestinal Barrier Function In A Mouse Model Of Food Allergy
    218. Baicalein Induces Cell Apoptosis Via The Mapk Pathway In Fro Anaplastic Thyroid Cancer Cells
    219. Baicalein Induces Cell Death In Murine T Cell Lymphoma Via Inhibition Of Thioredoxin System
    220. Baicalein Induces Cervical Cancer Apoptosis Through The Nf-Κb Signaling Pathway
    221. Baicalein Induces Functional Hypoxia-Inducible Factor-1Α And Angiogenesis
    222. Baicalein Induces G1 Arrest In Oral Cancer Cells By Enhancing The Degradation Of Cyclin D1 And Activating Ahr To Decrease Rb Phosphorylation
    223. Baicalein Induces Hela Cell Growth Inhibition By Down-Regulation Of Matrix Metalloproteinases And Activating Extracellular Signal-Regulated Kinase
    224. Baicalein Induces Human Osteosarcoma Cell Line Mg-63 Apoptosis Via Ros-Induced Bnip3 Expression
    225. Baicalein Induces Proliferation Inhibition In B16F10 Melanoma Cells By Generating Reactive Oxygen Species Via 12-Lipoxygenase
    226. Baicalein Induces The Apoptosis Of Hct116 Human Colon Cancer Cells Via The Upregulation Of Depp/Gadd45A And Activation Of Mapks
    227. Baicalein Induces The Apoptosis Of U251 Glioblastoma Cell Lines Via The Nf-Kb-P65-Mediated Mechanism
    228. Baicalein Induces Tumor Suppression In Triple Negative Breast Cancer By Mtor Inhibition Mediated Through Ddit4 Expression
    229. Baicalein Induction Of Hydroxyl Radical Formation Via 12-Lipoxygenase In Human Platelets: An Esr Study
    230. Baicalein Inhibites Multiple Myeloma Cells Proliferation And Migration By Interfering Wnt Signaling Pathway
    231. Baicalein Inhibition Of Hydrogen Peroxide-Induced Apoptosis Via Ros-Dependent Heme Oxygenase 1 Gene Expression
    232. Baicalein Inhibition Of Oxidative-Stress-Induced Apoptosis Via Modulation Of Erks Activation And Induction Of Ho-1 Gene Expression In Rat Glioma Cells C6
    233. Baicalein Inhibits Acinar‐To‐Ductal Metaplasia Of Pancreatic Acinal Cell Ar42J Via Improving The Inflammatory Microenvironment
    234. Baicalein Inhibits Adipocyte Differentiation By Enhancing Cox-2 Expression
    235. Baicalein Inhibits Agonist-And Tumor Cell-Induced Platelet Aggregation While Suppressing Pulmonary Tumor Metastasis Via Camp-Mediated Vasp Phosphorylation …
    236. Baicalein Inhibits Amadori-Glycated Albumin-Induced Mcp-1 Expression In Retinal Ganglion Cells Via A Microrna-124–Dependent Mechanism
    237. Baicalein Inhibits Angiogenesis Induced By Lipopolysaccharide Through Traf6 Mediated Toll-Like Receptor 4 Pathway
    238. Baicalein Inhibits Breast Cancer Growth Via Activating A Novel Isoform Of The Long Noncoding Rna Pax8‐As1‐N
    239. Baicalein Inhibits Cell Development, Metastasis And Emt And Induces Apoptosis By Regulating Erk Signaling Pathway In Osteosarcoma
    240. Baicalein Inhibits Cell Growth And Increases Cisplatin Sensitivity Of A549 And H460 Cells Via Mir‐424‐3P And Targeting Pten/Pi3K/Akt Pathway
    241. Baicalein Inhibits Cervical Cancer Progression Via Downregulating Long Noncoding Rna Bdlnr And Its Downstream Pi3 K/Akt Pathway
    242. Baicalein Inhibits Dextran Sulfate Sodium-Induced Mouse Colitis
    243. Baicalein Inhibits Dmba/Tpa-Induced Skin Tumorigenesis In Mice By Modulating Proliferation, Apoptosis, And Inflammation
    244. Baicalein Inhibits Dmba–Dna Adduct Formation By Modulating Cyp1A1 And Cyp1B1 Activities
    245. Baicalein Inhibits Energy-Dependent Efflux Pump Activity In Candida Species
    246. Baicalein Inhibits Epithelial To Mesenchymal Transition Via Downregulation Of Cyr61 And Loxl-2 In Mda-Mb231 Breast Cancer Cells
    247. Baicalein Inhibits Fibronectin-Induced Epithelial–Mesenchymal Transition By Decreasing Activation And Upregulation Of Calpain-2
    248. Baicalein Inhibits Formation Of Α‐Synuclein Oligomers Within Living Cells And Prevents Aβ Peptide Fibrillation And Oligomerisation
    249. Baicalein Inhibits Growth Of Cervical Carcinoma Via Inducing Apoptosis Of Tumor Cells In Vivo
    250. Baicalein Inhibits Growth Of Epstein-Barr Virus-Positive Nasopharyngeal Carcinoma By Repressing The Activity Of Ebna1 Q-Promoter
    251. Baicalein Inhibits Hepatocellular Carcinoma Cells Through Suppressing The Expression Of Cd24
    252. Baicalein Inhibits Hmgb1 Release And Mmp-2/-9 Expression In Lipopolysaccharide-Induced Cardiac Hypertrophy
    253. Baicalein Inhibits Il-1Β-And Tnf-Α-Induced Inflammatory Cytokine Production From Human Mast Cells Via Regulation Of The Nf-Κb Pathway
    254. Baicalein Inhibits Il-6-Mediated Multiple Signaling Cascades Through Jak Family Kinase In Human Myeloma Cells.
    255. Baicalein Inhibits Inflammatory And Catabolic Gene Expression In Interleukin-1Beta-Induced Human Chondrocytes
    256. Baicalein Inhibits Interleukin-1Β-Induced Proliferation Of Human Rheumatoid Arthritis Fibroblast-Like Synoviocytes
    257. Baicalein Inhibits Lipid Accumulation By Regulating Early Adipogenesis And M-Tor Signaling
    258. Baicalein Inhibits Lipid Accumulation Through Regulation Of Mce And Cell Cycle During 3T3-L1 Adipocyte Differentiation.
    259. Baicalein Inhibits Matrix Metalloproteinase 1 Expression Via Activation Of Trpv 1‐Ca‐Erk Pathway In Ultraviolet B–Irradiated Human Dermal Fibroblasts
    260. Baicalein Inhibits Mcf-7 Cell Proliferation In Vitro, Induces Radiosensitivity, And Inhibits Hypoxia Inducible Factor
    261. Baicalein Inhibits Melanogenesis Through Activation Of The Erk Signaling Pathway
    262. Baicalein Inhibits Migration And Invasion Of Gastric Cancer Cells Through Suppression Of The Tgf‑Β Signaling Pathway
    263. Baicalein Inhibits Mitochondrial Apoptosis Induced By Oxidative Stress In Cardiomyocytes By Stabilizing March5 Expression
    264. Baicalein Inhibits Mmp-2 Expression In Human Ovarian Cancer Cells By Suppressing The P38 Mapk-Dependent Nf-Κb Signaling Pathway
    265. Baicalein Inhibits Mmps Expression Via A Mapk-Dependent Mechanism In Chondrocytes
    266. Baicalein Inhibits Neuroapoptosis Via Pathways In Sevoflurane Induced Rats
    267. Baicalein Inhibits Nuclear Factor-Κb And Apoptosis Via C-Flip And Mapk In D-Galn/Lps Induced Acute Liver Failure In Murine Models
    268. Baicalein Inhibits Orthotopic Human Non-Small Cell Lung Cancer Xenografts Via Src/Id1 Pathway
    269. Baicalein Inhibits Osteoclast Differentiation And Induces Mature Osteoclast Apoptosis
    270. Baicalein Inhibits Osteosarcoma Cell Proliferation And Invasion Through The Mir‑183/Ezrin Pathway
    271. Baicalein Inhibits Oxidative Stress-Induced Cellular Damage Via Antioxidant Effects
    272. Baicalein Inhibits Pancreatic Cancer Cell Proliferation And Invasion Via Suppression Of Nedd9 Expression And Its Downstream Akt And Erk Signaling Pathways
    273. Baicalein Inhibits Pi3K/Akt Signaling Pathway And Induces Autophagy Of Mgc-803 Cells
    274. Baicalein Inhibits Progression Of Gallbladder Cancer Cells By Downregulating Zfx
    275. Baicalein Inhibits Progression Of Osteosarcoma Cells Through Inactivation Of The Wnt/Β-Catenin Signaling Pathway
    276. Baicalein Inhibits Proliferation Activity Of Human Colorectal Cancer Cells Hct116 Through Downregulation Of Ezrin
    277. Baicalein Inhibits Proliferation And Collagen Synthesis Of Mice Fibroblast Cell Line Nih/3T3 By Regulation Of Mir-9/Insulin-Like Growth Factor-1 Axis
    278. Baicalein Inhibits Proliferation And Migration Of Bladder Cancer Cell Line T24 By Down-Regulation Of Microrna-106
    279. Baicalein Inhibits Proliferation Of Myeloma U266 Cells By Downregulating Ikzf1 And Ikzf3
    280. Baicalein Inhibits Prostate Cancer Cell Growth And Metastasis Via The Caveolin-1/Akt/Mtor Pathway
    281. Baicalein Inhibits Pulmonary Carcinogenesis-Associated Inflammation And Interferes With Cox-2, Mmp-2 And Mmp-9 Expressions In-Vivo
    282. Baicalein Inhibits Raf-1-Mediated Phosphorylation Of Mek-1 In C6 Rat Glioma Cells
    283. Baicalein Inhibits Staphylococcus Aureus Biofilm Formation And The Quorum Sensing System In Vitro
    284. Baicalein Inhibits Stx1 And 2 Of Ehe: Effects Of Baicalein On The Cytotoxicity, Production, And Secretion Of Shiga Toxins Of Enterohaemorrhagic Escherichia …
    285. Baicalein Inhibits The Enhancing Effects Of Cigarette Smoke Extract (Cse) On Inflammatory Cytokine Production In Il-1Beta Activated Mast Cells (35.5)
    286. Baicalein Inhibits The Growth Of Oral Squamous Cell Carcinoma Cells By Downregulating The Expression Of Transcription Factor Sp1
    287. Baicalein Inhibits The Il-1Β-Induced Inflammatory Response In Nucleus Pulposus Cells And Attenuates Disc Degeneration In Vivo
    288. Baicalein Inhibits The Invasion And Metastatic Capabilities Of Hepatocellular Carcinoma Cells Via Down-Regulation Of The Erk Pathway
    289. Baicalein Inhibits The Invasion Of Gastric Cancer Cells By Suppressing The Activity Of The P38 Signaling Pathway
    290. Baicalein Inhibits The Invasion Of Human Cervical Cancer Cells By Inhibiting The Hedgehog/Gli Signaling Pathway
    291. Baicalein Inhibits The Invasion, Migration And Epithelial-Mesenchymal Transition Of Bgc-823 Cells Through Nf-Κb/Snail Signaling Pathway
    292. Baicalein Inhibits The Migration And Invasion Of B16F10 Mouse Melanoma Cells Through Inactivation Of The Pi3K/Akt Signaling Pathway
    293. Baicalein Inhibits The Migration And Invasion Of Colorectal Cancer Cells Via Suppression Of The Akt Signaling Pathway
    294. Baicalein Inhibits The Migration And Invasive Properties Of Human Hepatoma Cells
    295. Baicalein Inhibits The Proliferation And Invasion Of Oral Squamous Cell Carcinoma And Its Possible Signaling Pathway
    296. Baicalein Inhibits The Proliferation Of Cervical Cancer Cells Through The Gsk3Β-Dependent Pathway
    297. Baicalein Inhibits Tnf-Α-Induced Nf-Κb Activation And Expression Of Nf-Κb-Regulated Target Gene Products
    298. Baicalein Inhibits Tumor Migration And Invasion By Modulating Cell Adhesion And Declining Rhoa Pathway In Highly Invasive Non-Small-Cell Lung Cancer Cells
    299. Baicalein Inhibits Tumor Progression By Inhibiting Tumor Cell Growth And Tumor Angiogenesis
    300. Baicalein Inhibits Α-Synuclein Oligomer Formation And Prevents Progression Of Α-Synuclein Accumulation In A Rotenone Mouse Model Of Parkinson’S Disease
    301. Baicalein Is A Potent In Vitro Inhibitor Against Both Reticulocyte 15-Human And Platelet 12-Human Lipoxygenases
    302. Baicalein Is An Available Anti-Atherosclerotic Compound Through Modulation Of Nitric Oxide-Related Mechanism Under Oxldl Exposure
    303. Baicalein Is Neuroprotective In Rat Mcao Model: Role Of 12/15-Lipoxygenase, Mitogen-Activated Protein Kinase And Cytosolic Phospholipase A2
    304. Baicalein Iud Baicalin As Inhibitors Of Hiv-1 Integrase
    305. Baicalein Liposome Encapsulation Rate Determination
    306. Baicalein Loaded In Tocol Nanostructured Lipid Carriers (Tocol Nlcs) For Enhanced Stability And Brain Targeting
    307. Baicalein Loaded Polysorbate 80 Nanostructured Lipid Carriers Offered Enhanced Stability And In Vitro Drug Release
    308. Baicalein Lowers Intraocular Pressure And Increases Outflow Facility In Mouse Eye
    309. Baicalein Lowers Intraocular Pressure In Gerbils
    310. Baicalein Mediates Inhibition Of Migration And Invasiveness Of Skin Carcinoma Through Ezrin In A431 Cells
    311. Baicalein Mitigates Radiation-Induced Enteritis By Improving Endothelial Dysfunction
    312. Baicalein Modulates Nrf2/Keap1 System In Both Keap1-Dependent And Keap1-Independent Mechanisms
    313. Baicalein Modulates Stress-Resistance And Life Span In C. Elegans Via Skn-1 But Not Daf-16
    314. Baicalein Neutralizes Hypercholesterolemia-Induced Aggravation Of Cardiac Oxidative Injury
    315. Baicalein Neutralizes Hypercholesterolemia-Induced Aggravation Of Oxidative Injury In Rats
    316. Baicalein Or Scutellarein And Doxifluridine Combined
    317. Baicalein Overcomes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Resistance Via Two Different Cell-Specific Pathways In Cancer Cells But Not In Normal Cells
    318. Baicalein Potently Inhibits Rho Kinase Activity And Suppresses Actin Stress Fiber Formation In Angiotensin Ii-Stimulated H9C2 Cells
    319. Baicalein Potently Suppresses Angiogenesis Induced By Vascular Endothelial Growth Factor Through The P53/Rb Signaling Pathway Leading To G1/S Cell Cycle Arrest
    320. Baicalein Preconditioning Modulates Hepatocellular Injury Following Liver Ischemia And Reperfusion In Rats Via Anti-Inflammatory And Antioxidant Signaling
    321. Baicalein Preconditioning Protects Cardiomyocytes From Ischemia-Reperfusion Injury Via Mitochondrial Oxidant Signaling
    322. Baicalein Pretreatment Confers Cardioprotection Against Acute Myocardial Infarction By Activating The Endothelial Nitric Oxide Synthase Signaling Pathway And …
    323. Baicalein Pretreatment Protects Against Liver Ischemia/Reperfusion Injury Via Inhibition Of Nf-Κb Pathway In Mice
    324. Baicalein Pretreatment Reduces Liver Ischemia/Reperfusion Injury Via Induction Of Autophagy In Rats
    325. Baicalein Preventive Treatment Confers Optimal Cardioprotection By Pten/Akt/No Activation
    326. Baicalein Prevents 6-Hydroxydopamine-Induced Dopaminergic Dysfunction And Lipid Peroxidation In Mice
    327. Baicalein Prevents 6-Hydroxydopamine-Induced Mitochondrial Dysfunction In Sh-Sy5Y Cells Via Inhibition Of Mitochondrial Oxidation And Up-Regulation Of Dj-1 Protein …
    328. Baicalein Prevents 6-Ohda/Ascorbic Acid-Induced Calcium-Dependent Dopaminergic Neuronal Cell Death
    329. Baicalein Prevents Human Prion Protein-Induced Neuronal Cell Death By Regulating Jnk Activation
    330. Baicalein Prolongs The Lifespan Of Drosophila Melanogaster Through Antioxidation Activity
    331. Baicalein Promotes Angiogenesis And Odontoblastic Differentiation Via The Bmp And Wnt Pathways In Human Dental Pulp Cells
    332. Baicalein Promotes Neuronal And Behavioral Recovery After Intracerebral Hemorrhage Via Suppressing Apoptosis, Oxidative Stress And Neuroinflammation
    333. Baicalein Promotes Ppar-Β-Mediated Alternative Activation Of Microglia In Alleviating Experimental Autoimmune Encephalomyelitis (164.4)
    334. Baicalein Promotes The Apoptosis Of Hela Cells By Inhibiting Erk1/2 Expression
    335. Baicalein Protect Pancreatic Injury In Rats With Severe Acute Pancreatitis By Inhibiting Pro-Inflammatory Cytokines Expression
    336. Baicalein Protects Against 6-Ohda-Induced Neurotoxicity Through Activation Of Keap1/Nrf2/Ho-1 And Involving Pkcα And Pi3K/Akt Signaling Pathways
    337. Baicalein Protects Against Cardiac Hypertrophy Through Blocking Mek‐Erk1/2 Signaling
    338. Baicalein Protects Against Doxorubicin‐Induced Cardiotoxicity By Attenuation Of Mitochondrial Oxidant Injury And Jnk Activation
    339. Baicalein Protects Against Endothelial Cell Injury By Inhibiting The Tlr4/Nf‑Κb Signaling Pathway
    340. Baicalein Protects Against Hypertension Associated With Diabetes: Effect On Vascular Reactivity And Stiffness
    341. Baicalein Protects Against Oxldl-Caused Oxidative Stress And Inflammation By Modulation Of Ampk-Alpha
    342. Baicalein Protects Against Polymicrobial Sepsis-Induced Liver Injury Via Inhibition Of Inflammation And Apoptosis In Mice
    343. Baicalein Protects Against Retinal Ischemia By Antioxidation, Antiapoptosis, Downregulation Of Hif-1Α, Vegf, And Mmp-9 And Upregulation Of Ho-1
    344. Baicalein Protects Against Rotenone-Induced Neurotoxicity Through Induction Of Autophagy
    345. Baicalein Protects Against The Development Of Angiotensin Ii-Induced Abdominal Aortic Aneurysms By Blocking Jnk And P38 Mapk Signaling
    346. Baicalein Protects Against Type 2 Diabetes Via Promoting Islet Β-Cell Function In Obese Diabetic Mice
    347. Baicalein Protects C6 Glial Cells Against Hydrogen Peroxide-Induced Oxidative Stress And Apoptosis Through Regulation Of The Nrf2 Signaling Pathway
    348. Baicalein Protects Cardiomyocytes Against H2O2-Induced Mitochondrial Injury
    349. Baicalein Protects Cardiomyocytes Against Mitochondrial Oxidant Injury Associated With Jnk Inhibition And Mitochondrial Akt Activation
    350. Baicalein Protects Chicken Embryonic Cardiomyocyte Against Hypoxia–Reoxygenation Injury Via Μ-And Δ-But Not Κ-Opioid Receptor Signaling
    351. Baicalein Protects Cortical Neurons From Β-Amyloid (25-35) Induced Toxicity
    352. Baicalein Protects Hippocampal Neuronal Ht22 Cells From Er Stress-Induced Apoptosis By Modulating Unfolded Protein Responses-Associated Proteins
    353. Baicalein Protects Ht22 Murine Hippocampal Neuronal Cells Against Endoplasmic Reticulum Stress-Induced Apoptosis Through Inhibition Of Reactive Oxygen …
    354. Baicalein Protects Human Melanocytes From H2O2-Induced Apoptosis Via Inhibiting Mitochondria-Dependent Caspase Activation And The P38 Mapk Pathway
    355. Baicalein Protects Human Skin Cells Against Ultraviolet B-Induced Oxidative Stress
    356. Baicalein Protects Human Vitiligo Melanocytes From Oxidative Stress Through Activation Of Nf-E2-Related Factor2 (Nrf2) Signaling Pathway
    357. Baicalein Protects Isoproterenol Induced Myocardial Ischemic Injury In Male Wistar Rats By Mitigating Oxidative Stress And Inflammation
    358. Baicalein Protects Mice Against Radiation-Induced Dna Damages And Genotoxicity
    359. Baicalein Protects Normal Human Epidermal Keratinocytes Against Bullous Pemphigoid Immunoglobulin G-Induced Alteration
    360. Baicalein Protects Rat Brain Mitochondria Against Chronic Cerebral Hypoperfusion-Induced Oxidative Damage
    361. Baicalein Protects Rat Cardiomyocytes From Hypoxia/Reoxygenation Damage Via A Prooxidant Mechanism
    362. Baicalein Protects Rat Insulinoma Ins-1 Cells From Palmitate-Induced Lipotoxicity By Inducing Ho-1
    363. Baicalein Protects Rats With Diabetic Cardiomyopathy Against Oxidative Stress And Inflammation Injury Via Phosphatidylinositol 3-Kinase (Pi3K)/Akt Pathway
    364. Baicalein Protects Renal Tubular Epithelial Cells Againsthypoxia-Reoxygenation Injury
    365. Baicalein Protects Tert‑Butyl Hydroperoxide‑Induced Hepatotoxicity Dependent Of Reactive Oxygen Species Removal
    366. Baicalein Protects The Brain Against Neuron Impairments Induced By Mptp In C57Bl/6 Mice
    367. Baicalein Reduced Hepatic Fat Accumulation By Activating Ampk In Oleic Acid-Induced Hepg2 Cells And High-Fat Diet-Induced Non-Insulin Resistant Mice
    368. Baicalein Reduces Airway Injury In Allergen And Il-13 Induced Airway Inflammation
    369. Baicalein Reduces Angiogenesis In The Inflammatory Microenvironment Via Inhibiting The Expression Of Ap-1
    370. Baicalein Reduces E46K Α‐Synuclein Aggregation In Vitro And Protects Cells Against E46K Α‐Synuclein Toxicity In Cell Models Of Familiar Parkinsonism
    371. Baicalein Reduces Endometriosis By Suppressing The Viability Of Human Endometrial Stromal Cells Through The Nuclear Factor‑Κb Pathway In Vitro
    372. Baicalein Reduces Inflammatory Process In A Rodent Model Of Diabetic Retinopathy
    373. Baicalein Reduces Lipopolysaccharide-Induced Inflammation Via Suppressing Jak/Stats Activation And Ros Production
    374. Baicalein Reduces Liver Injury Induced By Myocardial Ischemia And Reperfusion
    375. Baicalein Reduces Oxidative Stress In Cho Cell Cultures And Improves Recombinant Antibody Productivity
    376. Baicalein Reduces The Invasion Of Glioma Cells Via Reducing The Activity Of P38 Signaling Pathway.
    377. Baicalein Reduces The Occurrence Of Cirrhotic Endotoxemia By Reducing Intestinal Mucosal Apoptosis
    378. Baicalein Reduces Β‐Amyloid And Promotes Nonamyloidogenic Amyloid Precursor Protein Processing In An Alzheimer’S Disease Transgenic Mouse Model
    379. Baicalein Represses Tgf-Β1-Induced Fibroblast Differentiation Through The Inhibition Of Mir-21
    380. Baicalein Rescues Delayed Cooling Via Preservation Of Akt Activation And Akt-Mediated Phospholamban Phosphorylation
    381. Baicalein Rescues Delayed Therapeutic Hypothermia In Cardioprotection
    382. Baicalein Restrains Proliferation, Migration, And Invasion Of Human Malignant Melanoma Cells By Down-Regulating Colon Cancer Associated Transcript-1
    383. Baicalein Retards Proliferation And Collagen Deposition By Activating P38Mapk‐Jnk Via Microrna‐29
    384. Baicalein Reverses Chronic Stress-Induced Ovarian Cancer Promotion Through Gaba Receptors
    385. Baicalein Reverses Hypoxia-Induced 5-Fu Resistance In Gastric Cancer Ags Cells Through Suppression Of Glycolysis And The Pten/Akt/Hif-1Α Signaling Pathway
    386. Baicalein Reverses The Methamphetamine-Induced Striatal Dopaminergic Neurotoxicity In Mice
    387. Baicalein Reverts L-Valine-Induced Persistent Sodium Current Up-Modulation In Primary Cortical Neurons
    388. Baicalein Selectively Induce Apoptosis In Human Leukemia K562 Cells
    389. Baicalein Selectively Induces Apoptosis In Activated Lymphocytes And Ameliorates Concanavalin A-Induced Hepatitis In Mice
    390. Baicalein Sensitizes Hepatocellular Carcinoma Cells To 5-Fu And Epirubicin By Activating Apoptosis And Ameliorating P-Glycoprotein Activity
    391. Baicalein Significantly Protects Human Retinal Pigment Epithelium Cells Against H2O2-Induced Oxidative Stress By Scavenging Reactive Oxygen Species And …
    392. Baicalein Stimulates Fibroblast Growth Factor 21 Expression By Up-Regulating Retinoic Acid Receptor-Related Orphan Receptor Α In C2C12 Myotubes
    393. Baicalein Stimulates Osteoblast Differentiation Via Coordinating Activation Of Map Kinases And Transcription Factors
    394. Baicalein Suppress Emt Of Breast Cancer By Mediating Tumor-Associated Macrophages Polarization
    395. Baicalein Suppresses 17-Β-Estradiol-Induced Migration, Adhesion And Invasion Of Breast Cancer Cells Via The G Protein-Coupled Receptor 30 Signaling Pathway
    396. Baicalein Suppresses Egf-Induced Proliferation And Migration Of Glioma Cells Via Egfr/Akt Signaling Pathways
    397. Baicalein Suppresses Hypoxia-Induced Hif-1Α Protein Accumulation And Activation Through Inhibition Of Reactive Oxygen Species And Pi 3-Kinase/Akt Pathway In Bv2 …
    398. Baicalein Suppresses Metastasis Of Breast Cancer Cells By Inhibiting Emt Via Downregulation Of Satb1 And Wnt/Β-Catenin Pathway
    399. Baicalein Suppresses Non Small Cell Lung Cancer Cell Proliferation, Invasion And Notch Signaling Pathway
    400. Baicalein Suppresses Repeat Tau Fibrillization By Sequestering Oligomers
    401. Baicalein Suppresses Stem Cell-Like Characteristics In Radio-And Chemoresistant Mda-Mb-231 Human Breast Cancer Cells Through Up-Regulation Of Ifit2
    402. Baicalein Suppresses Tau Fibrillization By Sequestering Oligomers
    403. Baicalein Suppresses The Androgen Receptor (Ar)-Mediated Prostate Cancer Progression Via Inhibiting The Ar Nc Dimerization And Ar-Coactivators Interaction
    404. Baicalein Suppresses The Proliferation Of Acute T-Lymphoblastic Leukemia Jurkat Cells By Inhibiting The Wnt/Β-Catenin Signaling
    405. Baicalein Suppresses The Proliferation Of Human Cervical Cancer Cells Via Notch 1/Hes Signaling Pathway
    406. Baicalein Suppresses The Sos Response System Of Staphylococcus Aureus Induced By Ciprofloxacin
    407. Baicalein Suppresses The Viability Of Mg-63 Osteosarcoma Cells Through Inhibiting C-Myc Expression Via Wnt Signaling Pathway
    408. Baicalein Synergy Lenalidomide To Induce Apoptosis Of Myeloma Cell
    409. Baicalein Targets Gtpase‐Mediated Autophagy To Eliminate Liver Tumor–Initiating Stem Cell–Like Cells Resistant To Mtorc1 Inhibition
    410. Baicalein Treatment Promotes Osteoblast Proliferation And Osteogenic Differentiation Through Activation Of Immediate Early Response 3
    411. Baicalein Triazole Prevents Respiratory Tract Infection By Rsv Through Suppression Of Oxidative Damage
    412. Baicalein Triggers Autophagy And Inhibits The Protein Kinase B/Mammalian Target Of Rapamycin Pathway In Hepatocellular Carcinoma Hepg2 Cells
    413. Baicalein Triggers Mitochondria-Mediated Apoptosis And Enhances The Antileukemic Effect Of Vincristine In Childhood Acute Lymphoblastic Leukemia Ccrf-Cem Cells
    414. Baicalein Upregulates Ddit4 Expression Which Mediates Mtor Inhibition And Growth Inhibition In Cancer Cells
    415. Baicalein, A Bioflavonoid, Prevents Cisplatin-Induced Acute Kidney Injury By Up-Regulating Antioxidant Defenses And Down-Regulating The Mapks And Nf-Κb …
    416. Baicalein, A Component Of Scutellaria Baicalensis, Attenuates Kidney Injury Induced By Myocardial Ischemia And Reperfusion
    417. Baicalein, A Component Of Scutellaria Baicalensis, Induces Apoptosis By Mcl-1 Down-Regulation In Human Pancreatic Cancer Cells
    418. Baicalein, A Component Of Scutellaria Radix From Huang-Lian-Jie-Du-Tang (Hljdt), Leads To Suppression Of Proliferation And Induction Of Apoptosis In Human …
    419. Baicalein, A Constituent Of Scutellaria Baicalensis, Reduces Glutamate Release And Protects Neuronal Cell Against Kainic Acid-Induced Excitotoxicity In Rats
    420. Baicalein, A Flavonoid Extracted From A Methanolic Extract Of Oroxylum Indicum Inhibits Proliferation Of A Cancer Cell Line In Vitro Via Induction Of Apoptosis
    421. Baicalein, A Flavonoid, Causes Prolonged Estrus And Suppressed Fertility Output Upon Prenatal Exposure In Female Mice
    422. Baicalein, A Natural Anti-Cancer Compound, Alters Microrna Expression Profiles In Bel-7402 Human Hepatocellular Carcinoma Cells
    423. Baicalein, A Natural Product, Selectively Activating Ampkα2 And Ameliorates Metabolic Disorder In Diet-Induced Mice
    424. Baicalein, A Novel Anti-Diabetic Compound
    425. Baicalein, A Novel Apoptotic Agent For Hepatoma Cell Lines: A Potential Medicine For Hepatoma
    426. Baicalein, An Active Component Of Scutellaria Baicalensis Georgi, Improves Cardiac Contractile Function In Endotoxaemic Rats Via Induction Of Heme Oxygenase-1 And …
    427. Baicalein, An Active Component Of Scutellaria Baicalensis Georgi, Induces Apoptosis In Human Colon Cancer Cells And Prevents Aom/Dss-Induced Colon …
    428. Baicalein, An Active Component Of Scutellaria Baicalensis Georgi, Prevents Lysophosphatidylcholine-Induced Cardiac Injury By Reducing Reactive Oxygen …