Adapting proteostasis for disease intervention Biological and chemical approaches to diseases of proteostasis deficiency Proteostasis and aging The proteostasis network and its decline in ageing The […]

AMPK activation: a therapeutic target for type 2 diabetes? AMPK activators–potential therapeutics for metabolic and other diseases AMPK activation, a preventive therapeutic target in the transition […]

… (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary … … […]

Biguanide-associated lactic acidosis: case report and review of the literature Lactic acidosis in biguanide-treated diabetics: a review of 330 cases Biguanides and NIDDM Pharmacophoric features of […]

Sulfonylureas Sulfonylureas in NIDDM Sulfonylureas. Sulfonylureas Sulfonylureas Why, Which, and How? Sulfonylureas and Sulfonylthioureas. Effects on lipid profile of dipeptidyl peptidase 4 inhibitors, pioglitazone, acarbose, and […]

Recent developments in synthetic α-glucosidase inhibitors: A comprehensive review with structural and molecular insight Synthesis of novel indenoquinoxaline derivatives as potent α-glucosidase inhibitors Studies on α-glucosidase […]

Comparative review of dipeptidyl peptidase‐4 inhibitors and sulphonylureas Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences Dipeptidyl peptidase‐4 (DPP‐4) inhibitors for type 2 diabetes mellitus Safety […]

Nutrient-sensing mechanisms and pathways Nutrient sensing and signaling: NPKS Nutrient-sensing mechanisms across evolution Perspective: hexosamines and nutrient sensing Nutrient sensing and inflammation in metabolic diseases Structure […]

Aging, inflammation and the environment Molecular mechanisms of aging-associated inflammation Oxidative stress and vascular inflammation in aging Source of chronic inflammation in aging Exercise, inflammation and […]