GSK3 inhibitors: development and therapeutic potential The conundrum of GSK3 inhibitors: is it the dawn of a new beginning? Discovery and development of GSK3 inhibitors for […]

SIRT1 suppresses activator protein-1 transcriptional activity and cyclooxygenase-2 expression in macrophages Sirt 1 activator inhibits the AGE-induced apoptosis and p53 acetylation in human vascular endothelial cells […]

AMPK activation: a therapeutic target for type 2 diabetes? AMPK activators–potential therapeutics for metabolic and other diseases AMPK activation, a preventive therapeutic target in the transition […]

Advanced glycation end-product cross-link breakers: a novel approach to cardiovascular pathologies related to the aging process Cross-link breakers as a new therapeutic approach to cardiovascular disease […]

Mitohormesis How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis) Mitohormesis and metabolic health: The interplay between ROS, cAMP and […]

 Slimming food supplements adulterated with sibutramine and phenolphthalein  Too Fat Part Two!… … , double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of […]

Reversal of obesity by targeted ablation of adipose tissue Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ Reversal of obesity-related […]

… (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary … … a supplement containing […]

FNDC5/irisin is not only a myokine but also an adipokine Irisin/FNDC5-An updated review Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway Irisin and FNDC5 in retrospect: […]