The results obtained indicate that A. sinensis extract can prevent the OVX-induced bone loss in rats via estrogen-independent mechanism.
Antioxidant - The antioxidant activities of three popular ingredients of traditional Chinese medicine, namely Angelica sinensis (AS), Lycium barbarum (LB) and Poria cocos (PC) were evaluated in this study.
The results showed that aqueous extracts of these crude drugs exhibited antioxidant activities in a concentration‐dependent manner. All extracts displayed an inhibitory effect on FeCl2‐ascorbic acid induced lipid peroxidation in rat liver homogenate in vitro.
Angiogenic Effects - This investigation describes the angiogenic effects of Angelica sinensis (AS) extract on human endothelial cells (HUVEC) in vitro and zebrafish in vivo. The wound healing migration assay illustrated that a dramatic increase in migration could be measured in AS extract‐treated HUVEC. Meanwhile, the number of invaded cells and the mean tube length were significantly increased in AS extract treatment groups.
All results suggest that Angelica sinensis extract can promote angiogenesis.
Neuroprotection - Ligustilide (LIG) is a principal active ingredient of traditional Chinese medicine, Radix Angelica sinensis, which has ve