Benefits of Oleuropein

Dragons Blood

February 10, 2019

Aloe Arborescens

February 12, 2019

Oleuropein

Oleuropein is a phenylethanoid, a type of phenolic compound and is one of the major bioactive constituents in green olives, olive leaves, and argan oil. Some of oleuropein’s documented pharmacological activities include antioxidant, anti-inflammatory, anti-atherogenic, anti-cancer activities, antimicrobial activity, anti-Alzheimer’s, antiviral activity, hypolipidemic and hypoglycemic effect.

Scientists have been able to isolate a molecule in olive that has health and life extending properties. Oleuropein is a type of polyphenol which has been shown to reduce cholesterol, blood pressure, prevent cancer, and oxidative stress.
The compound itself is tangy and bitter that can be found in the higher quality olive oils. This compound also contains a power antioxidant , anti inflammatory and disease fighting capabilities.
The unexpected benefits and unique properties of oleuropein provide ample rationale for continued use and study of this key component of the Mediterranean diet to promote human health.

Alzheimer's Disease - The present review summarizes the findings on the beneficial effects against neurodegeneration and other peripheral inflammatory and degenerative diseases of oleuropein aglycone (OLE), a natural phenol abundant in the extra virgin olive oil.

The data presently available suggest that OLE could provide a protective and therapeutic effect against a number of pathologies, including AD as well as obesity, type 2 diabetes, non-alcoholic hepatitis, and other natural or experimentally-induced pathological conditions.

In particular, the recent data on the cellular and molecular correlates of OLE neuroprotection suggest it could also play a therapeutic role against AD.

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Oxidative Stress - This study aimed to evaluate the significance of supplementation of oleuropein in reducing oxidative stress and hyperglycemia in alloxan-induced diabetic rabbits.

After induction of diabetes, a significant rise in plasma and erythrocyte malondialdehyde (MDA) and blood glucose as well as alteration in enzymatic and non-enzymatic antioxidants was observed in all diabetic animals.

These results demonstrate that oleuropein may be of advantage in inhibiting hyperglycemia and oxidative stress induced by diabetes and suggest that administration of oleuropein may be helpful in the prevention of diabetic complications associated with oxidative stress.

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Antioxidant - The main reaction products obtainable by the hydrolysis of commercially available oleuropein by hyperthermophilic β-glycosidase were purified and structurally characterized by UV and ¹H and ¹³C NMR analyses.

Their antioxidant activity, in particular their capacity to inhibit the fatty acid peroxidation rate, was studied. This molecule, under the reaction conditions (pH 7.0, 60 °C) required for β-glycosidase activity, rapidly gives rise to phenylethanol.

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Antimicrobial - Oleuropein, t