FNDC5/irisin is not only a myokine but also an adipokine Irisin/FNDC5-An updated review Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway Irisin and FNDC5 in retrospect: an exercise hormone or a transmembrane receptor? Are skeletal muscle FNDC5 gene expression and irisin release regulated by exercise and related to health? Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models FNDC5 alleviates oxidative stress and cardiomyocyte apoptosis in doxorubicin-induced cardiotoxicity via activating AKT FNDC5: a novel player in metabolism and metabolic syndrome Fndc5 knockdown significantly decreased neural differentiation rate of mouse embryonic stem cells Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies New insights into the cellular activities of Fndc5/Irisin and its signaling pathways Expression of the irisin precursor FNDC5 in skeletal muscle correlates with aerobic exercise performance in patients with heart failure Elevated skeletal muscle irisin precursor FNDC5 mRNA in obese OLETF rats FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to … A role for FNDC5/Irisin in the beneficial effects of exercise on the brain and in neurodegenerative diseases Increased FNDC5/Irisin expression in human hepatocellular carcinoma Does PGC1α/FNDC5/BDNF elicit the beneficial effects of exercise on neurodegenerative disorders? Myostatin knockout drives browning of white adipose tissue through activating the AMPK‐PGC1α‐Fndc5 pathway in muscle FNDC5/Irisin inhibits pathological cardiac hypertrophy Fndc5 overexpression facilitated neural differentiation of mouse embryonic stem cells FNDC5/Irisin–their role in the nervous system and as a mediator for beneficial effects of exercise on the brain FNDC5 overexpression and irisin ameliorate glucose/lipid metabolic derangements and enhance lipolysis in obesity Hepatic FNDC5 is a potential local protective factor against Non-Alcoholic Fatty Liver Exercise training does not increase muscle FNDC5 protein or mRNA expression in pigs FNDC5 alleviates hepatosteatosis by restoring AMPK/mTOR-mediated autophagy, fatty acid oxidation, and lipogenesis in mice FNDC5 is produced in the stomach and associated to body composition Irisin and FNDC5: effects of 12-week strength training, and relations to muscle phenotype and body mass composition in untrained women FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity A polymorphism in the Irisin-encoding gene (FNDC5) associates with hepatic steatosis by differential miRNA binding to the 3′ UTR The diagnostic value of FNDC5/irisin in renal cell cancer Progress and challenges in the biology of FNDC5 and irisin Glucocorticoid receptor positively regulates transcription of FNDC5 in the liver Can resistance exercise alter irisin levels and expression profiles of FNDC5 and UCP1 in rats? FNDC5 expression and circulating irisin levels are modified by diet and hormonal conditions in hypothalamus, adipose tissue and muscle Common Genetic Variation in the Human FNDC5 Locus, Encoding the Novel Muscle-Derived 'Browning' Factor Irisin, Determines Insulin Sensitivity FNDC5 attenuates obesity-induced cardiac hypertrophy by inactivating JAK2/STAT3-associated inflammation and oxidative stress Association of metabolic parameters and rs726344 in FNDC5 with serum irisin concentrations Effects of swimming exercise on serum Irisin and bone FNDC5
Advanced glycation end-product cross-link breakers: a novel approach to cardiovascular pathologies related to the aging process Cross-link breakers as a new therapeutic approach to cardiovascular disease Potential clinical utility of advanced glycation end product cross-link breakers in age-and diabetes-associated disorders Collagen cross-link breakers: a beginning of a new era in the treatment of cardiovascular changes associated with aging, diabetes, and hypertension Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein AI The cross-link breaker, N-phenacylthiazolium bromide prevents vascular advanced glycation end-product accumulation Potential Usefulness of AGE Cross–Link Breakers for Modulating the Progression of AMD Advanced glycation end-product cross-link breakers: a novel therapeutic pathway for cardiovascular disease Cross-link Breakers and Inhibitors Cleavage of in vitro and in vivo formed lens protein cross-links by a novel cross-link breaker Therapeutic potential of AGE inhibitors and breakers of AGE protein cross-links In vitro antiglycation and cross-link breaking activities of Sri Lankan low-grown orthodox orange pekoe grade black tea (Camellia sinensis L) Characteristics, formation, and pathophysiology of glucosepane: a major protein cross-link Inhibitors and breakers of advanced glycation endproducts (AGEs): a review Effect of the age cross-link breaker alagebrium on anterior segment physiology, morphology, and ocular age and rage Restraining cross-links responsible for the mechanical properties of collagen fibers: natural and artificial Glycation end-product cross-link breaker reduces collagen and improves cardiac function in aging diabetic heart Therapeutic options to reduce advanced glycation end products in patients with diabetes mellitus: A review Cross-linking of glycated collagen in the pathogenesis of arterial and myocardial stiffening of aging and diabetes Biochemical process of AGEs formation in complications of hyperglycemia-induced diabetes and its pathological damage effects: A possible target for new drugs Evolving concepts in advanced glycation, diabetic nephropathy, and diabetic vascular disease The breakdown of preformed advanced glycation end products reverses erectile dysfunction in streptozotocin‐induced diabetic rats: Preventive versus curative … Crosslink breakers: a new approach to cardiovascular therapy AGE, RAGE, and ROS in diabetic nephropathy Laser Sub–Fractionation to Assess the Elasticity of Ageing Human Bruch's Membrane: Reversal Implications for AMD Diabetic heart disease Advanced glycation end‐products (AGEs) and heart failure: pathophysiology and clinical implications Novel cross-link breaker based on zwitterion structure: Synthesis, structure and druggability studies Advanced Glycation End Products in Diabetes‐Associated Atherosclerosis and Renal Disease: Interventional Studies Advanced glycation end product cross-link breaker attenuates diabetes-induced cardiac dysfunction by improving sarcoplasmic reticulum calcium handling The diabetic myocardium Arterial stiffness and cardiovascular therapy A cross-link breaker has sustained effects on arterial and ventricular properties in older rhesus monkeys Treating diastolic heart failure with AGE crosslink breakers: thinking outside the heart failure box Synthesis and Evaluation of Novel [1,2,4]Triazolo[5,1‐c][1,2,4]‐triazines and Pyrazolo[5,1‐c][1,2,4]triazines as Potential Antidiabetic Agents Consensus ensemble neural network modeling of Maillard reaction inhibitors Non-enzymatic glycation and oxidative stress in chronic illnesses and diabetes mellitus Advanced Glycation End Product Cross‐Linking: Pathophysiologic Role and Therapeutic Target in Cardiovascular Disease Chelation: a fundamental mechanism of action of AGE inhibitors, AGE breakers, and other inhibitors of diabetes complications The AGE/RAGE axis in diabetes‐accelerated atherosclerosis
Mitohormesis How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis) Mitohormesis and metabolic health: The interplay between ROS, cAMP and sirtuins Mitohormesis: promoting health and lifespan by increased levels of reactive oxygen species (ROS) Unraveling the truth about antioxidants: mitohormesis explains ROS-induced health benefits Metformin promotes lifespan through mitohormesis via the peroxiredoxin PRDX-2 Muscle mitohormesis promotes longevity via systemic repression of insulin signaling … of the beneficial alterations in cellular physiology produced by caloric restriction, intermittent fasting, exercise and dietary phytonutrients:“Mitohormesis” for health and … Opposite effects of statins on mitochondria of cardiac and skeletal muscles: a 'mitohormesis' mechanism involving reactive oxygen species and PGC-1 Mitohormesis primes tumor invasion and metastasis Mitohormesis in exercise training Nutritional ketosis and mitohormesis: potential implications for mitochondrial function and human health Epigallocatechin-3-gallate promotes healthy lifespan through mitohormesis during early-to-mid adulthood in Caenorhabditis elegans Mitohormesis, an antiaging paradigm Mitohormesis in mice via sustained basal activation of mitochondrial and antioxidant signaling The mitochondrial unfolded protein response and mitohormesis: a perspective on metabolic diseases Enoxacin extends lifespan of C. elegans by inhibiting miR-34-5p and promoting mitohormesis Molecular hydrogen protects against oxidative stress-induced SH-SY5Y neuroblastoma cell death through the process of mitohormesis A review of the inhibition of the mitochondrial ATP synthase by IF1 in vivo: reprogramming energy metabolism and inducing mitohormesis Muscle mitohormesis promotes cellular survival via serine/glycine pathway flux Mitohormesis reprogrammes macrophage metabolism to enforce tolerance Exercise-induced mitohormesis for the maintenance of skeletal muscle and healthspan extension Regulation of the H+-ATP synthase by IF1: a role in mitohormesis Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling Mitohormesis, UPRmt, and the complexity of mitochondrial DNA landscapes in cancer … status in human dermal fibroblasts using HMG-CoA reductase inhibitor over a broad range of concentrations. From mitohormesis to mitochondrial dysfunction … Mitohormesis in hypothalamic POMC neurons mediates regular exercise-induced high-turnover metabolism N‐acetyl‐l‐tyrosine is an intrinsic triggering factor of mitohormesis in stressed animals Mitohormesis; Potential implications in neurodegenerative diseases Rictor/mTORC2 deficiency enhances keratinocyte stress tolerance via mitohormesis Endogenous metabolites promote stress resistance through induction of mitohormesis Adhesion-mediated mechanosignaling forces mitohormesis Mitohormesis in muscle cells: a morphological, molecular, and proteomic approach A variety of mild stresses upregulate stanniocalcin-1 (STC-1) and induce mitohormesis in neural crest-derived cells N-Propargylglycine: a unique suicide inhibitor of proline dehydrogenase with anticancer activity and brain-enhancing mitohormesis properties L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis Effects of low concentrations of rotenone upon mitohormesis in SH-SY5Y cells Fragile lifespan expansion by dietary mitohormesis in C. elegans Sestrin2, a regulator of thermogenesis and mitohormesis in brown adipose tissue Protect the species with mitohormesis? Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis How N-Acetylcysteine Supplementation Affects Redox Regulation, Especially at Mitohormesis and Sarcohormesis Level: Current Perspective Mitohormesis: another pleiotropic effect of statins? Mitohormesis Life-Span Extension by Axenic Dietary Restriction Is Independent of the Mitochondrial Unfolded Protein Response and Mitohormesis in Caenorhabditis elegans Differences in mitochondrial coupling
Slimming food supplements adulterated with sibutramine and phenolphthalein Too Fat Part Two!... … , double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects (S)-3-[(Benzyloxy) methyl] morpholine hydrochloride: a nonstimulant appetite suppressant without conventional neurotransmitter releasing properties 1-(m-Chlorophenyl) piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain 10. Drugs Affecting Cholinergic Neurotransmission 101 Things to Do Before You Diet: Because Looking Great Isn't Just about Losing Weight 19 Diabetes and Herbal 3 CNTF and Related Neurokines 360-Degree Perspectives on Obesity 365 Skinny Smoothies: Healthy, Never-Boring Recipes with 52 Weekly Shopping Lists for Stress-Free Weight Loss 5-HT2B receptor antagonists inhibit fibrosis and protect from RV heart failure 5-HTP: The natural way to overcome depression, obesity, and insomnia 5-Hydroxyindole-2-carboxylic acid amides: novel histamine-3 receptor inverse agonists for the treatment of obesity 50 Ways to Boost Your Metabolism: How Mustard, Red Wine, and Days at the Beach Can Help You Lose Weight & Stay Healthy 7 Acetylcholinesterase inhibitory activity of spices and culinary herbs 7 Weight Management 9 Best Thermogenic Fat Burners in 2022 for Weight Loss A behavioral approach to weight management A Behavioural Genetic Model of the Mechanisms Underlying the Link Between Obesity and Dimensional Measures of Attention-Deficit/Hyperactivity Disorder (ADHD) A bidirectional network for appetite control in larval zebrafish A bidirectional network for appetite control in larval zebrafish A bidirectional network for appetite control in zebrafish A botanical approach to managing obesity A cholinergic basal forebrain feeding circuit modulates appetite suppression A combined healthy strategy for successful weight loss, weight maintenance and improvement of hepatic lipid metabolism A Comparison Study between Orlistat and Moringa Oleifera as an Appetite Suppressant in Case of Obese Patients A content analysis of marketing on the packages of dietary supplements for weight loss and muscle building A contextual analysis of obesity and smoking among women in Oklahoma City A Cost-Effective Analysis of Appetite Suppressants for Obesity Treatment in a Managed Care Organization A critical review on obesity: Herbal approach, bioactive compounds, and their mechanism A dual role for astroglia in substituted amphetamine-induced serotonin nerve degeneration: Neuroprotective and neurotoxic A flavonoid-rich fraction of Monolluma quadrangula inhibits xanthine oxidase and ameliorates potassium oxonate-induced hyperuricemia in rats A Functional Magnetic Resonance Imaging Study Evaluating the Effects of Intranasal Insulin on Food Related Reward and Appetite A GC–EI-MS-MS method for simultaneous determination of seven adulterants in slimming functional foods A herbal approach to obesity Management: a review A high-throughput fluorescence-based assay system for appetite-regulating gene and drug screening A history of neuromuscular block and its antagonism A low carbohydrate diet: Treating obesity related disorders in adults A low-carbohydrate, ketogenic diet versus a low-fat diet to treat obesity and hyperlipidemia: a randomized, controlled trial A Mechanistic Review of Anti-Obesity Drugs A medicinal plants survey for treatment of obesity A Multi-Ingredient Supplement Protects against Obesity and Infertility in Western Diet-Fed Mice A multimodal approach to the treatment of obesity A natural solution for obesity: Bioactives for the
Reversal of obesity by targeted ablation of adipose tissue Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ Reversal of obesity-related hypoadiponectinemia by lifestyle intervention: a controlled, randomized study in obese adolescents Reversal of diet-induced obesity and diabetes in C57BL/6J mice Appearance of brown adipocytes in white adipose tissue during CL 316,243-induced reversal of obesity and diabetes in Zucker fa/fa rats Leptin Activation of Corticosterone Production in Hepatocytes May Contribute to the Reversal of Obesity and Hyperglycemia in Leptin-Deficient ob/ob Mice Hypertrophy of brown adipocytes in brown and white adipose tissues and reversal of diet-induced obesity in rats treated with a β3-adrenoceptor agonist Trends in fatness and the origins of obesity Reversal of obesity in the genetically obese fa/fa Zucker rat with an ephedrine/methylxanthines thermogenic mixture Reversal of Obesity-and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption.... Mifepristone (RU 486), a blocker of type II glucocorticoid and progestin receptors, reverses a dietary form of obesity Obesity and sarcopenia after menopause are reversed by sex hormone replacement therapy Myocardial fatty acid oxidation rates remain elevated in ob/ob mice despite reversal of obesity and diabetes by caloric restriction Body weight regulation in obese and obese-reduced rats. Inflammation and the IKKβ/IκB/NF-κB axis in obesity-and diet-induced insulin resistance Polycythemia of obesity: further studies of its mechanism and a report of two additional cases Brain responses to obesogenic diets and diet-induced obesity Development of obesity in transgenic mice after genetic ablation of brown adipose tissue Hypothalamic obesity: the autonomic hypothesis and the lateral hypothalamus Role of Endoplasmic Reticulum Stress and c-Jun NH2-Terminal Kinase Pathways in Inflammation and Origin of Obesity and Diabetes Severe orthostatic hypotension following weight reduction surgery The role of beta3-adrenergic receptors in control of brown and white adipose tissues and of energy balance: Reversal of obesity by CL 316,243, a new beta3 … The liver in obesity and type 2 diabetes mellitus Effects of fasting and refeeding on blood pressure are determined by nutritional state, not by body weight change Maternal obesity is associated with younger age at obesity onset in US adolescent offspring followed into adulthood Thematic review series: adipocyte biology. Sympathetic and sensory innervation of white adipose tissue The inflammatory syndrome: the role of adipose tissue cytokines in metabolic disorders linked to obesity Using mouse models to dissect the genetics of obesity Energy balance in reversible obesity Effect of diet on adipose tissue and skeletal muscle VLDL receptor and LPL: implications for obesity and hyperlipidemia Pathophysiologic changes of obesity Role of the autonomic nervous system in the development of ventromedial hypothalamic obesity Aspirin as a promoter of ephedrine-induced thermogenesis: potential use in the treatment of obesity The effects of subdiaphragmatic vagotomy in rats with ventromedial hypothalamic obesity Brain somatic cross-talk: ghrelin, leptin and ultimate challengers of obesity Reduction of elevated serum retinol binding protein in obese children by lifestyle intervention: association with subclinical inflammation Pathogenesis of type 2 diabetes mellitus Internal regulation and the evolution of normal growth as the basis for prevention of obesity in
… (GH) analog can antagonize the ability of native GH to promote differentiation of 3T3-F442A preadipocytes and stimulate insulin-like and lipolytic activities in primary … … a supplement containing conjugated linoleic acid on dairy performance, milk fatty acid composition, and adipose tissue reactivity to lipolytic challenge in mid … … analogs of lysolecithin and their use in a continuous spectrophotometric assay for lysophospholipases, a method with potential applicability to other lipolytic enzymes … and reduction of fat stores on the antilipolytic alpha 2-adrenoceptor in hamster adipocytes: comparison with adenosine and beta-adrenergic lipolytic … … and Yarrowia lipolytica strains in dried fermented sausage manufacture. Part 1: Evaluation of their effects on microbial evolution, lipolytic and proteolytic patterns … breast adenocarcinoma (MCF-7) cells proliferation in co-culture with human adipocytes in three dimensional collagen gel matrix: norepinephrine as a lipolytic … … diabetes mellitus is the result of the inability to secrete insulin. Augmented insulin secretion normally limits the glycemic, but not the lipolytic or ketogenic, response to … … during postprandial lipemia parallels the response of triglyceride-rich lipoproteins in type 2 diabetes: no relationship between apoA-V and postheparin plasma lipolytic … … high‐density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and type 2 diabetes mellitus: role of lipolytic enzymes, lecithin: cholesterol … … human breast adenocarcinoma [MCF-7] cells proliferation in co-culture with human adipocytes in three dimensional collagen gel matrix: norepinephrine as a lipolytic … … HYPERSENSITIVE RESPONSE OF BEAN INOCULATED WITH PSEUDOMONAS SYRINGAE PV. PHASEOLICOLA RACE 1 (PHASEOLUS VULGARIS, LIPOLYTIC … … in biological materials. II. The measurement of adenosine 3', 5'-monophosphate in tissues and the role of the cyclic nucleotide in the lipolytic response of fat to … … IN THE EARLY PERIODS AFTER IONIZING RADIATION AND THE EFFECT OF WHOLE-BODY ALPHAIRRADIATION ON LIPOLYTIC ENZYME INDUCTION BY … … of 1-substituted 6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinolines: inhibition of 3H-dopamine accumulation by rat brain slices and lipolytic activity with isolated mouse … … of a versatile cassette for directional genome walking using cassette ligation-mediated PCR and its application in the cloning of complete lipolytic genes from Bacillus … … of an axenic fungal isolate of aspergillus sp.(mbl-1511) and its subsequent improvement for enhanced extracellular lipolytic potential through monoculture … … of Corticotropin. III. The Synthesis of L-Histidyl-L-phenylalanyl-L-arginyl-L-tryptophan, the Smallest Peptide Exhibiting the Melanocyte-stimulating and the Lipolytic … … of hypertriglyceridemia by two diets rich either in unsaturated fatty acids or in carbohydrates: effects on lipoprotein subclasses, lipolytic enzymes, lipid transfer proteins … … of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic … … of preadipocytes with fish oil, mixed oil, or soybean oil-based lipid emulsions have differential effects on the regulation of lipogenic and lipolytic genes in mature 3T3 … … of sodium taurodeoxycholate, CaCl2 and albumin on the action of pancreatic lipase on droplets of trioleoylglycerol and the release of lipolytic products into aqueous … … overview of Tityus cisandinus scorpion venom: Transcriptome and mass fingerprinting reveal conserved toxin homologs across the Amazon region and novel lipolytic … … PHOSPHOLIPASE C (CLOSTRIDIUM PERFRINGENS α TOXIN) AND OF INSULIN ON LIPOLYSIS STIMULATED BY LIPOLYTIC HORMONES AND THEOPHYLLINE … regulation of hormone-sensitive lipase in intact adipocytes: identification of phosphorylated sites
Anti-obesogenic and antidiabetic effects of plants and mushrooms Medicinal plants and phytochemicals with anti-obesogenic potentials: A review The anti-obesogenic effects of dietary berry fruits: A review Potential of enhancing anti-obesogenic agriceuticals by applying sustainable fertilizers during plant cultivation Mechanisms of action for the anti-obesogenic activities of phytochemicals The anti-obesogenic effects and underpinning mechanisms of fermented plant-based foods: A review Anti-obesogenic effects of WY14643 (PPAR-alpha agonist): Hepatic mitochondrial enhancement and suppressed lipogenic pathway in diet-induced obese mice Antioxidative, anti-inflammatory, anti-obesogenic, and antidiabetic properties of tea polyphenols—The positive impact of regular tea consumption as an … The conversion of β-carotene to vitamin A in adipocytes drives the anti-obesogenic effects of β-carotene in mice Saponins are responsible for the anti-obesogenic activity of Acacia concinna Dietary n-3 long-chain polyunsaturated fatty acids upregulate energy dissipating metabolic pathways conveying anti-obesogenic effects in mice Phenolic Profile, Antioxidant Activity, and Anti-obesogenic Bioactivity of Mao Luang Fruits (Antidesma bunius L.) Prawn shell chitosan has anti-obesogenic properties, influencing both nutrient digestibility and microbial populations in a pig model Anti-obesogenic effect of apple cider vinegar in rats subjected to a high fat diet Potential Anti-obesogenic Effects of Ginkgo biloba Observed in Epididymal White Adipose Tissue of Obese Rats Potential anti-obesogenic properties of non-digestible carbohydrates: specific focus on resistant dextrin The Allium Derivate Propyl Propane Thiosulfinate Exerts Anti-Obesogenic Effects in a Murine Model of Diet-Induced Obesity Prawn Shell Chitosan Exhibits Anti-Obesogenic Potential through Alterations to Appetite, Affecting Feeding Behaviour and Satiety Signals In Vivo Anti-Obesogenic Effects of Sulforaphane-Rich Broccoli (Brassica oleracea var. italica) Sprouts and Myrosinase-Rich Mustard (Sinapis alba L.) Seeds In Vitro and In … Selection of Thai medicinal plants with anti-obesogenic potential via in vitro methods Caffeic acid and hydroxytyrosol have anti-obesogenic properties in zebrafish and rainbow trout models Arabinoxylans and gelled arabinoxylans used as anti-obesogenic agents could protect the stability of intestinal microbiota of rats consuming high-fat diets Socioeconomic status and use of obesogenic and anti-obesity medications in the United States: a population-based study Anti-obesogenic and hypolipidemic effects of a glucagon-like peptide-1 receptor agonist derived from the saliva of the Gila monster Anti‐obesogenic effects of calcium prevent changes in the GLP‐1 profile in adult rats primed by early weaning Copaiba oleoresin presents anti-obesogenic effect and mitigates inflammation and redox imbalance in adipose tissue Anti-obesity natural products tested in juvenile zebrafish obesogenic tests and mouse 3T3-L1 adipogenesis assays Putative hormone with anti-obesogenic and insulin-sensitizing effect Zebrafish obesogenic test identifies anti‐adipogenic fraction in Moringa oreifera leaf extracts A long-term obesogenic high-fat diet in mice partially dampens the anti-frailty benefits of late-life intermittent fasting The Anti-Obesogenic Effect of Lean Fish Species Is Influenced by the Fatty Acid Composition in Fish Fillets Obesity causes irreversible mitochondria failure in visceral adipose tissue despite successful anti-obesogenic lifestyle-based interventions Molecular Mechanisms of Adipogenesis: The Anti-Obesogenic Role of AMP-Activated Protein Kinase and Recently Reported Plant Products Mechanistic analysis of Thai medicinal plants on anti-obesogenic activity [an abstract of dissertation and a summary of dissertation review] Investigating the antioxidant, immunomodulatory and anti-obesogenic propertiesof novel BSG-derived extracts and their potential as
Of mice and men: The physiological role of adipose triglyceride lipase (ATGL) Hints on ATGL implications in cancer: beyond bioenergetic clues Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl) Recent advances on the role of ATGL in cancer Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1 ATGL has a key role in lipid droplet/adiposome degradation in mammalian cells The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-α in 3T3-L1 adipocytes and is a target for transactivation by PPARγ ATGL promotes autophagy/lipophagy via SIRT1 to control hepatic lipid droplet catabolism FoxO1 controls insulin-dependent adipose triglyceride lipase (ATGL) expression and lipolysis in adipocytes Desnutrin/ATGL is regulated by AMPK and is required for a brown adipose phenotype Cold-induced thermogenesis depends on ATGL-mediated lipolysis in cardiac muscle, but not brown adipose tissue ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids Long non-coding RNA NEAT1-modulated abnormal lipolysis via ATGL drives hepatocellular carcinoma proliferation Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte triglyceride content through adipose triglyceride lipase (ATGL) Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2 ATGL-catalyzed lipolysis regulates SIRT1 to control PGC-1α/PPAR-α signaling Dysregulation of lipolysis and lipid metabolism in visceral and subcutaneous adipocytes by high-fat diet: role of ATGL, HSL, and AMPK AMPK phosphorylates desnutrin/ATGL and hormone-sensitive lipase to regulate lipolysis and fatty acid oxidation within adipose tissue Insulin inhibits lipolysis in adipocytes via the evolutionarily conserved mTORC1-Egr1-ATGL-mediated pathway SIRT1 controls lipolysis in adipocytes via FOXO1-mediated expression of ATGL Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover Prolonged AICAR-induced AMP-kinase activation promotes energy dissipation in white adipocytes: novel mechanisms integrating HSL and ATGL Skeletal muscle PLIN proteins, ATGL and CGI-58, interactions at rest and following stimulated contraction Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction Impact of reduced ATGL-mediated adipocyte lipolysis on obesity-associated insulin resistance and inflammation in male mice Fat-specific protein 27 (FSP27) interacts with adipose triglyceride lipase (ATGL) to regulate lipolysis and insulin sensitivity in human adipocytes The minimal domain of adipose triglyceride lipase (ATGL) ranges until leucine 254 and can be activated and inhibited by CGI-58 and G0S2, respectively LncRNA SRA promotes hepatic steatosis through repressing the expression of adipose triglyceride lipase (ATGL) Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells Adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL) deficiencies affect expression of lipolytic activities in mouse adipose tissues Adipose triglyceride lipase (ATGL) expression in human skeletal muscle is type I (oxidative) fiber specific Fasting, but not exercise, increases adipose triglyceride lipase (ATGL) protein and reduces G (0)/G (1) switch gene 2 (G0S2) protein and mRNA content in human … Effect of endurance training intensity (low, moderate and high) on the expression of skeletal muscle ATGL protein and serum
The lipase inhibitor tetrahydrolipstatin binds covalently to the putative active site serine of pancreatic lipase A new pancreatic lipase inhibitor isolated from the roots of Actinidia arguta A new pancreatic lipase inhibitor from Broussonetia kanzinoki Quercetin is a promising pancreatic lipase inhibitor in reducing fat absorption in vivo Weight Gain Reduction in Mice Fed Panax ginseng Saponin, a Pancreatic Lipase Inhibitor Anti-obesity effects of galangin, a pancreatic lipase inhibitor in cafeteria diet fed female rats Inhibition of pancreatic lipase in vitro by the covalent inhibitor tetrahydrolipstatin Cetilistat (ATL-962), a novel pancreatic lipase inhibitor, ameliorates body weight gain and improves lipid profiles in rats Anti-obesity activity of hen egg anti-lipase immunoglobulin yolk, a novel pancreatic lipase inhibitor Antiobesity action of ɛ-polylysine, a potent inhibitor of pancreatic lipase Relationship between improved postprandial lipemia and low-density lipoprotein metabolism during treatment with tetrahydrolipstatin, a pancreatic lipase inhibitor High-Resolution Bioassay Profiling with Complemented Sensitivity and Resolution for Pancreatic Lipase Inhibitor Screening Proteinaceous pancreatic lipase inhibitor from the seed of Litchi chinensis Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini I. Producing organism, fermentation, isolation and biological activity Lipstatin, an inhibitor of pancreatic lipase, produced by Streptomyces toxytricini II. Chemistry and structure elucidation Elucidating the Biosynthetic Pathway for Vibralactone: A Pancreatic Lipase Inhibitor with a Fused Bicyclic β‐Lactone Kojic acid repurposing as a pancreatic lipase inhibitor and the optimization of its production from a local Aspergillus oryzae soil isolate Development of QSAR model using machine learning and molecular docking study of polyphenol derivatives against obesity as pancreatic lipase inhibitor Studies on the antiobesity activity of tetrahydrolipstatin, a potent and selective inhibitor of pancreatic lipase. Cassia grandis Lf nanodispersion is a hypoglycemic product with a potent α-glucosidase and pancreatic lipase inhibitor effect … aldol-lactonization (TMAL) reaction: A concise and highly diastereoselective route to β-lactones applied to the total synthesis of the potent pancreatic lipase inhibitor … In-vitro functional efficacy of extracts from Phyllanthus emblica, Eucalyptus globulus, Tinospora cordifolia as pancreatic lipase inhibitor and source of anti-oxidant in … Phytochemical and Biological Profile of Moricandia arvensis (L.) DC.: An Inhibitor of Pancreatic Lipase Theophylline extracted from fu brick tea affects the metabolism of preadipocytes and body fat in mice as a pancreatic lipase inhibitor The community management of chylous fistula using a pancreatic lipase inhibitor (orlistat) Proteinous pancreatic lipase inhibitor is responsible for the antiobesity effect of young barley (Hordeum vulgare L.) leaf extract Peptide inhibitor of pancreatic lipase selected by phage display using different elution strategies Synthesis and Study of a Lipophilic α-Keto Amide Inhibitor of Pancreatic Lipase Utilization of Agro-Waste of Piper longum for a Potential Pancreatic Lipase Inhibitor 5-Hydroxy-7-(4′-hydroxy-3′-methoxyphenyl)-1-phenyl-3-heptanone: a pancreatic lipase inhibitor isolated from Alpinia officinarum Operon for biosynthesis of lipstatin, the beta-lactone inhibitor of human pancreatic lipase Saponin isolates from cucumber (Cucumis sativus L.) fruit mesocarp and their activity as pancreatic lipase inhibitor Functional Imaging and Inhibitor Screening of Human Pancreatic Lipase by a Resorufin-Based Fluorescent Probe Large spectral changes accompany the conformational transition of human pancreatic lipase induced by acylation with the inhibitor
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