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February 6, 2017SUPERNOVA
February 6, 2017THERMO
$275.00
INTRODUCING
“THERMO”
The Ultimate Fat Burning Formula & Glucose Disposal Agent
300 1/8 teaspoon servings per bag
DOSAGE:
A little more frequent is more effective than a lot all at once.
Start with 1/8 teaspoon in 2-4 oz of hot water
every 4-6 hours and adjust accordingly.
For OPTIMUM RESULTS to preserve muscle and burn fat take 1/8 to 1/4 teaspoon PREWORKOUT in FASTED STATE
- BENEFITS INCLUDE:
- GLUCONEOGENESIS INHIBITION. (STOPS MUSCLES FROM BEING ROBBED OF THEIR AMINO ACIDS TO PRODUCE GLUCOSE)
- INCREASED INSULIN SENSITIVITY THROUGH INSULIN MIMETICS AND INSULIN SENSITIZERS.
- ENHANCED SHUTTLING OF GLUCOSE INTO MUSCLES.
- LOWERED AND REGULATED BLOOD SUGAR.
- TARGETED REMOVAL OF STUBBORN SUBCUTANEOUS AND VISCERAL FAT.
- EFFICIENTLY DETERRING INSULIN RESISTANT INDUCED NEW FAT STORAGE.
- ENHANCED MENTAL FOCUS, ENERGY AND CLARITY.
- AMPK ACTIVATION.
- MTOR INHIBITION.
- DIABETIC AND PREDIABETIC PROTECTION WHEN COMBINED WITH LOW GLYCEMIC LOAD DIET.
Flavonoids activate thermogenesis and prevent obesity through several mechanisms:
1. Inducing white adipose tissue (WAT) browning: Flavonoids have been shown to induce the browning of white adipocytes, which involves the conversion of white adipose tissue into a more metabolically active brown-like adipose tissue. This process increases energy expenditure and promotes thermogenesis, as brown adipose tissue (BAT) is specialized in generating heat. By promoting WAT browning, flavonoids enhance thermogenesis and increase energy consumption, which can help prevent obesity.
2. Activation of the sympathetic nervous system (SNS): Flavonoids activate the sympathetic nervous system, which plays a crucial role in regulating thermogenesis. Activation of the SNS leads to the release of adrenaline and thyroid hormones, which are involved in the stimulation of thermogenesis. Adrenaline and thyroid hormones increase metabolic rate and energy expenditure, contributing to the prevention of obesity.
3. Activation of signaling pathways: Flavonoids activate specific signaling pathways involved in thermogenesis and energy metabolism. One of the key pathways is the AMP-activated protein kinase (AMPK)-PGC-1α/Sirt1 pathway. AMPK is a cellular energy sensor that regulates metabolism, and PGC-1α and Sirt1 are proteins involved in the regulation of thermogenesis and energy expenditure. Flavonoids activate these pathways, leading to increased thermogenesis and energy expenditure.
4. Regulation of peroxisome proliferator-activated receptors (PPARs): Flavonoids can modulate the activity of peroxisome proliferator-activated receptors (PPARs), which are nuclear receptors involved in the regulation of lipid metabolism and energy balance. Activation of PPARs can promote thermogenesis and increase energy expenditure. Flavonoids can activate PPAR signaling pathways, leading to the prevention of obesity.
5. Inhibition of weight gain and metabolic diseases: By inducing WAT browning, activating thermogenesis, and increasing energy expenditure, flavonoids can inhibit weight gain and prevent metabolic diseases such as obesity. Flavonoids help to improve glucose and lipid metabolism, reduce adiposity, and maintain energy balance, all of which contribute to the prevention of obesity.
Polyphenols activate thermogenesis and prevent obesity through several mechanisms:
1. Activation of Brown Adipose Tissue (BAT): Polyphenols, such as those found in green tea, can activate brown adipose tissue (BAT), which is responsible for non-shivering adaptive thermogenesis. BAT contains a protein called uncoupling protein 1 (UCP-1) that uncouples substrate oxidation from ATP synthesis, leading to the production of heat. Polyphenols can stimulate BAT through the activation of β3-adrenoreceptors and the sympathetic nervous system, resulting in increased thermogenesis and energy expenditure.
2. Increase in Energy Expenditure (EE): Polyphenols can increase energy expenditure by enhancing mitochondrial function and increasing ATP synthesis. They can activate peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α), a key regulator of mitochondrial biogenesis. By increasing the number and activity of mitochondria, polyphenols enhance oxidative phosphorylation and ATP production, leading to an increase in energy expenditure.
3. Enhancement of Fat Oxidation: Polyphenols can promote the oxidation of fatty acids, leading to increased fat metabolism. They can activate enzymes involved in fatty acid oxidation and stimulate the expression of genes related to lipid metabolism. By increasing fat oxidation, polyphenols can help to reduce fat accumulation and prevent obesity.
4. Synergistic Interactions: Some polyphenols, such as those found in green tea, exhibit synergistic interactions with caffeine and catecholamines. These interactions can enhance thermogenesis and fat oxidation. Caffeine can increase sympathetic neural release of catecholamines, while polyphenols can inhibit the degradation of catecholamines by inhibiting catechol-O-methyl transferase (COMT). This synergistic effect leads to increased thermogenesis and fat oxidation.
5. Regulation of Energy Balance: Polyphenols can help regulate energy balance by modulating appetite and satiety. They can affect the secretion of hormones involved in appetite control, such as leptin and ghrelin. By promoting satiety and reducing food intake, polyphenols can contribute to weight management and prevent obesity.
Ingredients & science
- Macrophage-Stimulating Activity of Polysaccharides Extracted from Fruiting Bodies of Coriolus versicolor (Turkey Tail Mushroom)
- Beta‐glucans in higher fungi and their health effects
- A review of research on the protein-bound polysaccharide (polysaccharopeptide, PSP) from the mushroom Coriolus versicolor (Basidiomycetes: Polyporaceae)
- Coriolus versicolor polysaccharide peptide slows progression of advanced non-small cell lung cancer
- Polysaccharopeptides of Coriolus versicolor: physiological activity, uses, and production
- Antitumor effects of a refined polysaccharide peptide fraction isolated from Coriolus versicolor: in vitro and in vivo studies
- Separation, purification, and α-glucosidase inhibition of polysaccharides from Coriolus versicolor LH1 mycelia
- Hypoglycemic effects of exo-biopolymers produced by five different medicinal mushrooms in STZ-induced diabetic rats
- In vitro chemopreventive effects of plant polysaccharides (Aloe barbadensis Miller, Lentinus edodes, Ganoderma lucidum and Coriolus versicolor)
- Anti-tumor effect of Coriolus versicolor methanol extract against mouse B16 melanoma cells: in vitro and in vivo study
- Hypoglycemic and hypolipidemic effects of ethanolic extract of Mirabilis jalapa L. root on normal and diabetic mice
- Experimental diabetes treated with trigonelline: effect on β cell and pancreatic oxidative parameters
- Study on Hypoglycemic Effect of Mirabilis jalapa on Adrenergic Model Mice [J]
- Antiviral and Antiviroid Activity of MAP-Containing Extracts from Mirabilis jalapa Roots
- Antinociceptive activity of Mirabilis jalapa in mice
- In-vitro antioxidant potential of methanolic extracts of Mirabilis jalapa Linn
- Biochemical analysis of Cassia fistula aqueous extract and phytochemically synthesized gold nanoparticles as hypoglycemic treatment for diabetes mellitus
- GC/MS and LC/MS analysis, and antioxidant and antimicrobial activities of various solvent extracts from Mirabilis jalapa tubers
- Antinociceptive effect of Mirabilis jalapa on acute and chronic pain models in mice
- Pharmacological study of antispasmodic activity of Mirabilis jalapa Linn flowers
- Evaluation of antioxidant and wound healing effects of alcoholic and aqueous extract of Ocimum sanctum Linn in rats
- Antioxidant activity and lipid-lowering effect of essential oils extracted from Ocimum sanctum L. leaves in rats fed with a high cholesterol diet
- Antidiabetic effects of the different fractions of ethanolic extracts of Ocimum sanctum in normal and alloxan induced diabetic rats
- Hypoglycemic effect of Ocimum sanctum leaf extract in normal and streptozotocin diabetic rats.
- Ethanolic extract of Ocimum sanctum leaves partially attenuates streptozotocin-induced alterations in glycogen content and carbohydrate metabolism in rats
- Effect of Ocimum sanctum leaf powder on blood lipoproteins, glycated proteins and total amino acids in patients with non-insulin-dependent diabetes mellitus
- Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic β-cells
- Antidiabetic, antihypercholesterolaemic and antioxidant effect of Ocimum sanctum (Linn) seed oil
- Randomized placebo-controlled, single blind trial of holy basil leaves in patients with noninsulin-dependent diabetes mellitus.
- Evaluation of hypoglycemic and antioxidant effect ofOcimum sanctum
- Naringenin prevents obesity, hepatic steatosis, and glucose intolerance in male mice independent of fibroblast growth factor 21
- Naringenin prevents dyslipidemia, apolipoprotein B overproduction, and hyperinsulinemia in LDL receptor–null mice with diet-induced insulin resistance
- Naringenin suppresses macrophage infiltration into adipose tissue in an early phase of high-fat diet-induced obesity
- DNA-protective effects of quercetin or naringenin in alloxan-induced diabetic mice
- Anti-inflammatory and antifibrotic effects of naringenin in diabetic mice
- Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes
- Antihyperglycemic and antioxidant effects of a flavanone, naringenin, in streptozotocin–nicotinamide-induced experimental diabetic rats
- Participation of antioxidant and cholinergic system in protective effect of naringenin against type-2 diabetes-induced memory dysfunction in rats
- Effect of citrus flavonoids on lipid metabolism and glucose-regulating enzyme mRNA levels in type-2 diabetic mice
- Inhibition of microsomal triglyceride transfer protein expression and apolipoprotein B100 secretion by the citrus flavonoid naringenin and by insulin involves activation
Oroxylum Indicum (Indian trumpet flower)
- Oroxylin A, a constituent of Oroxylum indicum inhibits adipogenesis and induces apoptosis in 3T3-L1 cells
- Modulation of liver function, antioxidant responses, insulin resistance and glucose transport by Oroxylum indicum stem bark in STZ induced diabetic rats
- Screening of six Ayurvedic medicinal plants for anti-obesity potential: An investigation on bioactive constituents from Oroxylum indicum (L.) Kurz bark
- Oroxylum indicum (L.) Kurz, an important Asian traditional medicine: from traditional uses to scientific data for its commercial exploitation
- Investigation of the anti-inflammatory and analgesic activities of ethanol extract of stem bark of Sonapatha Oroxylum indicum in vivo
- Oroxin A from Oroxylum indicum prevents the progression from prediabetes to diabetes in streptozotocin and high-fat diet induced mice
- Evaluation of antidiabetic and nephroprotective activity of Oroxylum indicum L Kurz and Quercus infectoria G Olivier
- Protective effect of aqueous extract of Oroxylum indicum Linn.(root bark) against DNBS-induced colitis in rats
- Antimicrobial and antiinflammatory activities of extracts and constituents of Oroxylum indicum (L.) Vent
- In vitro antioxidant activity from leaves of Oroxylum indicum (L.) Vent.-A North Indian highly threatened and vulnerable medicinal plant
Rauwolfia Serpentina (Indian Snakeroot)
- On the use of Rauwolfia serpentina in high blood pressure
- Methanolic root extract of Rauwolfia serpentina benth improves the glycemic, antiatherogenic, and cardioprotective indices in alloxan-induced diabetic mice
- Hypertension Treated with Rauwolfia canescens A Comparison with Rauwolfia serpentina
- Hypoglycaemic and hypolipidemic activities of Rauwolfia serpentina in alloxan-induced diabetic rats.
- A clinical trial of Rauwolfia serpentina in essential hypertension
- Phytochemical based strategies for pathogen control and antioxidant capacities of Rauwolfia serpentina extracts
- Methanolic root extract of Rauwolfia serpentina improves the glucose tolerance in wister mice
- Rauwolfia serpentina in the treatment of high blood pressure: a review of the literature
- Prospecting for novel plant-derived molecules of Rauvolfia serpentina as inhibitors of Aldose Reductase, a potent drug target for diabetes
- Rauwolfia serpentina in essential hypertension
- Obesity and thermogenesis related to the consumption of caffeine, ephedrine, capsaicin, and green tea
- Effects of capsaicin-containing yellow curry sauce on sympathetic nervous system activity and diet-induced thermogenesis in lean and obese young women
- Dietary capsaicin reduces obesity‐induced insulin resistance and hepatic steatosis in obese mice fed a high‐fat diet
- Effect of treatment with capsaicin on daily activities of patients with painful diabetic neuropathy
- Treatment of painful diabetic neuropathy with topical capsaicin. A multicenter, double-blind, vehicle-controlled study
- Topical capsaicin in painful diabetic neuropathy: effect on sensory function
- Topical capsaicin in painful diabetic neuropathy: controlled study with long-term follow-up
- The effect of cannabinoids on capsaicin-evoked calcitonin gene-related peptide (CGRP) release from the isolated paw skin of diabetic and non-diabetic rats
- A double-blind comparison of topical capsaicin and oral amitriptyline in painful diabetic neuropathy.
- Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus
- Anti-hyperlipidemic and hypoglycemic effects of Gynostemma pentaphyllum in the Zucker fatty rat
- Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): A randomized, double‐blind, placebo‐controlled trial
- Potential Hypoglycemic Effect of an Ethanol Extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db Mice
- Antidiabetic effect of Gynostemma pentaphyllum tea in randomly assigned type 2 diabetic patients
- Antidiabetic effects of add-on Gynostemma pentaphyllum extract therapy with sulfonylureas in type 2 diabetic patients
- Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients
- A novel insulin-releasing substance, phanoside, from the plant Gynostemma pentaphyllum
- Hypoglycemic effect of Gynostemma pentaphyllum saponins by enhancing the Nrf2 signaling pathway in STZ-inducing diabetic rats
- Heat-processed Gynostemma pentaphyllum extract improves obesity in ob/ob mice by activating AMP-activated protein kinase
- Effects of obesity on functional capacity
Rosa Canina (Trans-Tiliroside)
- Potent anti-obese principle from Rosa canina: structural requirements and mode of action of trans-tiliroside
- Effects of rose hip intake on risk markers of type 2 diabetes and cardiovascular disease: a randomized, double-blind, cross-over investigation in obese
- Rosehip extract inhibits lipid accumulation in white adipose tissue by suppressing the expression of peroxisome proliferator-activated receptor gamma
- Antidiabetic effect and antioxidant potential of Rosa canina fruits
- In vivo anti-inflammatory and antinociceptive activity of the crude extract and fractions from Rosa canina L. fruits
- Rosa canina extracts have antiproliferative and antioxidant effects on caco-2 human colon cancer
- Effects of Rosa canina L. fruit on glycemia and lipid profile in type 2 diabetic patients: a randomized, double-blind, placebo-controlled clinical trial
- Rose hip exerts antidiabetic effects via a mechanism involving downregulation of the hepatic lipogenic program
- Anti‐prediabetic effect of rose hip (Rosa canina) extract in spontaneously diabetic Torii rats
- Rosehip: an evidence based herbal medicine for inflammation and arthritis
botanical version of Metformin
- Novel weight‐reducing activity of Galega officinalis in mice
- A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity
- Administration of Galega officinalis in experimental and clinical investigations; a narrative review
- Alleviation of salt stress of symbiotic Galega officinalis L. (goat’s rue) by co-inoculation of Rhizobium with root-colonizing Pseudomonas
- Natural products in anti-obesity therapy
- Effect of Fabaceae (Galega Officinalis L.) consumption on levels of blood glucose, lipids and lipoproteins in streptozotocin-induced diabetic rats
- Anti-diabetic potential and Indian medicinal plants
- Antiplatelet Aggregation Activity of a Fraction Isolated from Galega officinalis L.
- The alkaloid-free fraction from Galega Officinalis extract prevents oxidative stress under experimental diabetes mellitus
- Cytotoxic, anti-inflammatory and antioxidant activities of four different extracts of Galega officinalis L (Goat’s rue)
- Recent findings of green tea extract AR25 (Exolise) and its activity for the treatment of obesity
- Effect of green tea extract on obese women: a randomized, double-blind, placebo-controlled clinical trial
- Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans
- Effects of green tea and EGCG on cardiovascular and metabolic health
- Assessment of DNA damage and lipid peroxidation in diabetic mice: effects of propolis and epigallocatechin gallate (EGCG)
- Epigallocatechin gallate (EGCG) attenuates high glucose‐induced insulin signaling blockade in human hepG2 hepatoma cells
- Effect of green tea on blood glucose levels and serum proteomic patterns in diabetic (db/db) mice and on glucose metabolism in healthy humans
- Epigallocatechin-3-O-gallate (EGCG) protects the insulin sensitivity in rat L6 muscle cells exposed to dexamethasone condition
- Protective effects of epigallocatechin gallate (EGCG) on streptozotocin-induced diabetic nephropathy in mice
- Effects of oral consumption of the green tea polyphenol EGCG in a murine model for human Sjogren’s syndrome, an autoimmune disease
- Calorie restriction-like effects of 30 days of resveratrol supplementation on energy metabolism and metabolic profile in obese humans
- Resveratrol exerts anti-obesity effects via mechanisms involving down-regulation of adipogenic and inflammatory processes in mice
- Long-term resveratrol administration reduces metabolic disturbances and lowers blood pressure in obese Zucker rats
- Resveratrol improves insulin sensitivity, reduces oxidative stress and activates the Akt pathway in type 2 diabetic patients
- Resveratrol, a red wine antioxidant, possesses an insulin-like effect in streptozotocin-induced diabetic rats
- AMP-activated protein kinase–deficient mice are resistant to the metabolic effects of resveratrol
- Effect of insulin and its combination with resveratrol or curcumin in attenuation of diabetic neuropathic pain: participation of nitric oxide and TNF‐alpha
- Resveratrol alleviates cardiac dysfunction in streptozotocin-induced diabetes: Role of nitric oxide, thioredoxin, and heme oxygenase
- Anti‐diabetic effects of resveratrol
- Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy
Ashwaghanda “Withania somnifera”
- Effects of Withania somnifera (Ashwagandha) and Terminalia arjuna (Arjuna) on physical performance and cardiorespiratory endurance in healthy young
- Effect of Ashwagandha (Withania somnifera) Root Powder Supplementation in Treatment of Hypertension
- Body weight management in adults under chronic stress through treatment with Ashwagandha root extract: a double-blind, randomized, placebo-controlled trial
- Hypoglycaemic and hypolipidaemic effects of Withania somnifera root and leaf extracts on alloxan-induced diabetic rats
- Effect of dietary intake ashwagandha roots powder on the levels of sex hormones in the diabetic and non-diabetic male rats
- Effect of Withania somnifera on Insulin Sensitivity in Non‐Insulin‐Dependent Diabetes Mellitus Rats
- Effect of withania somnifera on levels of sex hormones in the diabetic male rats
- The effect of chronic oral administration of Withania somnifera root on learning and memory in diabetic rats using passive avoidance test
- Reverse Ayurvedic pharmacology of Ashwagandha as an adaptogenic anti-diabetic plant: a pilot study
- The effect of oral administration of Withania somnifera root on formalin-induced pain in diabetic rats
- Effects of ingested turmeric oleoresin on glucose and lipid metabolisms in obese diabetic mice: a DNA microarray study
- Effects of fermented turmeric extracts on the obesity in rats fed a high-fat diet
- Curcumin inhibits adipogenesis in 3T3-L1 adipocytes and angiogenesis and obesity in C57/BL mice
- Modulatory effects of garlic, ginger, turmeric and their mixture on hyperglycaemia, dyslipidaemia and oxidative stress in streptozotocin–nicotinamide diabetic rats
- Curcumin, the active principle of turmeric (Curcuma longa), ameliorates diabetic nephropathy in rats
- Curcuminoids and Sesquiterpenoids in Turmeric (Curcuma longa L.) Suppress an Increase in Blood Glucose Level in Type 2 Diabetic KK-Ay Mice
- Hypolipidemic action of curcumin, the active principle of turmeric (Curcuma longa) in streptozotocin induced diabetic rats
- Efficacy of turmeric on blood sugar and polyol pathway in diabetic albino rats
- Effect of turmeric and curcumin on oxidative stress and antioxidant enzymes in streptozotocin-induced diabetic rat
- Curcumin and turmeric delay streptozotocin-induced diabetic cataract in rats
PIPERINE (black pepper)
- Effect of piperine in the regulation of obesity-induced dyslipidemia in high-fat diet rats
- Piperine, an active principle from Piper nigrum, modulates hormonal and apolipoprotein profiles in hyperlipidemic rats
- LIPID‐LOWERING EFFICACY OF PIPERINE FROM PIPER NIGRUM L. IN HIGH‐FAT DIET AND ANTITHYROID DRUG‐INDUCED HYPERCHOLESTEROLEMIC
- Effects of piperine on antioxidant pathways in tissues from normal and streptozotocin‐induced diabetic rats
- Evaluation of the effect of piperine per se on blood glucose level in alloxan-induced diabetic mice
- Antioxidant and anti-inflammatory effects of curcuminoid-piperine combination in subjects with metabolic syndrome
- Piperine, a natural bioenhancer, nullifies the antidiabetic and antioxidant activities of curcumin in streptozotocin-diabetic rats
- Protective effect of piperine on benzo (a) pyrene-induced lung carcinogenesis in Swiss albino mice
- Piperine reverses high fat diet-induced hepatic steatosis and insulin resistance in mice
- Effects of curcuminoids-piperine combination on systemic oxidative stress, clinical symptoms
- Effects and action mechanisms of berberine and Rhizoma coptidis on gut microbes and obesity in high-fat diet-fed C57BL/6J mice
- Structural changes of gut microbiota during berberine-mediated prevention of obesity and insulin resistance in high-fat diet-fed rats
- Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity
- Lipid-lowering effect of berberine in human subjects and rats
- Berberine inhibits adipogenesis in high-fat diet-induced obesity mice
- Berberine suppresses proinflammatory responses through AMPK activation in macrophages
- Modulating gut microbiota as an anti-diabetic mechanism of berberine
- Berberine improves glucose metabolism through induction of glycolysis
- Insulin sensitizing and insulinotropic action of berberine from Cortidis rhizoma
- Anti-diabetic effects of cinnamaldehyde and berberine and their impacts on retinol-binding protein 4 expression in rats with type 2 diabetes mellitus
stubborn fat alpha blocker
- Plasma catecholamine levels and lipid mobilization induced by yohimbine in obese and non-obese women.
- Cardiovascular effects of ephedrine, caffeine and yohimbine measured by thoracic electrical bioimpedance in obese women
- Yohimbine: the effects on body composition and exercise performance in soccer players
- Yohimbe Alkaloids–General Discussion
- The histological effects of mixed diet containing Pausinystalia yohimbe ground stem bark on the kidney of adult Wistar rats (Rattus norvegicus)
- Noradrenergic function in generalized anxiety disorder: effects of yohimbine in healthy subjects and patients with generalized anxiety disorder
- Yohimbine for erectile dysfunction: a systematic review and meta-analysis of randomized clinical trials
- Cameroonian medicinal plants: pharmacology and derived natural products
- Effects of methanolic extract of Pausinystalia yohimbe bark on blood glucose level in normal fasting rats
- Effects of methanolic extract of yohimbe bark (Pausinystalia yohimbe) on isolated rabbit aortic strip and rat uterus
Chlorogenic Acid (Green Coffee Bean Extract)
- The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese
- Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice
- Chlorogenic acid modifies plasma and liver concentrations of: cholesterol, triacylglycerol, and minerals in (fa/fa) Zucker rats
- Coffee acutely modifies gastrointestinal hormone secretion and glucose tolerance in humans: glycemic effects of chlorogenic acid and caffeine
- Acute effects of decaffeinated coffee and the major coffee components chlorogenic acid and trigonelline on glucose tolerance
- A chlorogenic acid-induced increase in GLP-1 production may mediate the impact of heavy coffee consumption on diabetes risk
- Chlorogenic acid stimulates glucose transport in skeletal muscle via AMPK activation: a contributor to the beneficial effects of coffee on diabetes
- Anti-diabetic and anti-lipidemic effects of chlorogenic acid are mediated by ampk activation
- Coffee consumption and risk of type 2 diabetes mellitus
- Chlorogenic acid and rutin play a major role in the in vivo anti-diabetic activity of Morus alba leaf extract on type II diabetic rats
- Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men
- The antihypertensive and positive inotropic diterpene forskolin: effects of structural modifications on its activity
- Antagonism of forskolin effects by adenosine in isolated hearts and ventricular myocytes
- Effect of chronic administration of forskolin on glycemia and oxidative stress in rats with and without experimental diabetes
- Insulin and glucagon releasing activity of coleonol (forskolin) and its effect on blood glucose level in normal and alloxan diabetic rats
- Insulin biosynthesis in HIT cells: effects of glucose, forskolin, IBMX, and dexamethasone
- Direct anesthetic-like effects of forskolin on the nicotinic acetylcholine receptors of PC12 cells.
- The ionic, electrical, and secretory effects of endogenous cyclic adenosine monophosphate in mouse pancreatic B cells: studies with forskolin
- The effects of forskolin and rolipram on cAMP, cGMP and free fatty acid levels in diet induced obesity
- Forskolin effects on the voltage-gated K+ conductance of human T cells
- Efficacy of Nigella sativa on serum free testosterone and metabolic disturbances in central obese male.
- Multiple molecular targets underlie the antidiabetic effect of Nigella sativa seed extract in skeletal muscle, adipocyte and liver cells
- Antihypertensive effect of Nigella sativa seed extract in patients with mild hypertension
- Effect of Nigella sativa on glucose concentration, lipid peroxidation, anti‐oxidant defence system and liver damage in experimentally‐induced diabetic rabbits
- Hypoglycemic effects of the volatile oil of Nigella sativa seeds
- Effects of Nigella sativa on oxidative stress and β‐cell damage in streptozotocin‐induced diabetic rats
- Biochemical effects of Nigella sativa L seeds in diabetic rats
- Mechanisms of the hypoglycaemic and immunopotentiating effects of Nigella sativa L. oil in streptozotocin-induced diabetic hamsters
- Isulinotropic properties of Nigella sativa oil in Streptozotocin plus Nicotinamide diabetic hamster
- Partial regeneration/proliferation of the β-cells in the Islets of Langerhans by Nigella sativa L. in streptozotocin-induced diabetic rats
Hoodia Gordonii (Queen of the Namib)
- Effects of 15-d repeated consumption of Hoodia gordonii purified extract on safety, ad libitum energy intake, and body weight in healthy, overweight women
- Hoodia gordonii in the treatment of obesity: A review
- Metabolic effect of short term administration of Hoodia gordonii, an herbal appetite suppressant
- Hoodia gordonii: a natural appetite suppressant
- Indigenous use of Hoodia gordonii and appetite suppression
- Complementary and alternative medicine for the treatment of obesity: a critical review
- Sympathomimetic activity of a Hoodia gordonii product: a possible mechanism of cardiovascular side effects
- Hoodia gordonii extract targets both adipose and muscle tissue to achieve weight loss in rats
- Metabolic response of short term calorie restriction and supplementation with Hoodia gordonii
- In vitro transport of the steroidal glycoside P57 from Hoodia gordonii across excised porcine intestinal and buccal tissue
- Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues
- Anti-obesity and anti-diabetic effects of fucoxanthin on diet-induced obesity conditions in a murine model
- Effect of medium-chain triacylglycerols on anti-obesity effect of fucoxanthin
- Fucoxanthin and its metabolite, fucoxanthinol, suppress adipocyte differentiation in 3T3-L1 cells
- Dietary Combination of Fucoxanthin and Fish Oil Attenuates the Weight Gain of White Adipose Tissue and Decreases Blood Glucose in Obese/Diabetic KK-Ay Mice
- Anti‐obese property of fucoxanthin is partly mediated by altering lipid‐regulating enzymes and uncoupling proteins of visceral adipose tissue in mice
- Fucoxanthin regulates adipocytokine mRNA expression in white adipose tissue of diabetic/obese KK-Ay mice
- Fucoxanthin and fucoxanthinol enhance the amount of docosahexaenoic acid in the liver of KKAy obese/diabetic mice
- Effects of dietary fucoxanthin on cholesterol metabolism in diabetic/obese KK-A y mice
- The carotenoid fucoxanthin from brown seaweed affects obesity
Bitter Melon (momordica charantia)
- Effects of Momordica charantia on insulin resistance and visceral obesity in mice on high-fat diet
- Antihyperglycemic effects of three extracts from Momordica charantia
- The effect of Momordica charantia and Mucuna pruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism
- Bitter melon (Momordica charantia L.) inhibits adipocyte hypertrophy and down regulates lipogenic gene expression in adipose tissue of diet-induced obese rats
- Effects of Momordica charantia powder on serum glucose levels and various lipid parameters in rats fed with cholesterol-free and cholesterol-enriched diets
- Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review
- Inhibition of increases in blood glucose and serum neutral fat by Momordica charantia saponin fraction
- An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract
- The insulin-releasing activity of the tropical plant momordica charantia.
- Antidiabetic Potentials of Momordica charantia: Multiple Mechanisms Behind the Effects
Banaba Leaf (Lagerstroemia speciosa)
- Antiobesity activity of extracts from Lagerstroemia speciosa L. leaves on female KK-Ay mice
- Antidiabetes and anti-obesity activity of Lagerstroemia speciosa
- Hypoglycemic activity of Lagerstroemia speciosa L. extract on streptozotocin-induced diabetic rat: Underlying mechanism of action
- An extract of Lagerstroemia speciosa L. has insulin-like glucose uptake–stimulatory and adipocyte differentiation–inhibitory activities in 3T3-L1 cells
- Antidiabetic activity of a standardized extract (Glucosol™) from Lagerstroemia speciosa leaves in type II diabetics: A dose-dependence study
- Active Compounds from Lagerstroemia speciosa, Insulin-like Glucose Uptake-Stimulatory/Inhibitory and Adipocyte Differentiation-Inhibitory Activities in 3T3-L1 Cells
- Hypoglycemic effect of Lagerstroemia speciosa (L.) Pers. on alloxan-induced diabetic mice
- The hypoglycemic effect of water extract from leaves of Lagerstroemia speciosa L. in streptozotocin-induced diabetic rats.
- Lagerstroemia speciosa extract inhibit TNF-induced activation of nuclear factor-κB in rat cardiomyocyte H9c2 cells
- Hypoglycemic effect of extracts from Lagerstroemia speciosa L. leaves in genetically diabetic KK-AY mice
Gymnema Sylvestre (Miracle Fruit)
- Antihyperglycemic Effects of Gymnemic Acid IV, a Compound Derived from Gymnema sylvestre Leaves in Streptozotocin-Diabetic Mice
- Comparative effects of chromium, vanadium and Gymnema sylvestre on sugar-induced blood pressure elevations in SHR
- Evaluation of antiobesity and cardioprotective effect of Gymnema sylvestre extract in murine model
- Antidiabetic effect of a leaf extract from Gymnema sylvestre in non-insulin-dependent diabetes mellitus patients
- Possible regeneration of the islets of Langerhans in streptozotocin-diabetic rats given Gymnema sylvestre leaf extracts
- Use of Gymnema sylvestre leaf extract in the control of blood glucose in insulin-dependent diabetes mellitus
- Gymnema sylvestre stimulates insulin release in vitro by increased membrane permeability
- Enzyme changes and glucose utilisation in diabetic rabbits: the effect of Gymnema sylvestre, R. Br.
- Antidiabetic and hypolipidemic activity of Gymnema sylvestre in alloxan induced diabetic rats
- In vitro callus and in vivo leaf extract of Gymnema sylvestre stimulate β-cells regeneration and anti-diabetic activity in Wistar rats
- Effects of exercise training and antioxidant R-ALA on glucose transport in insulin-sensitive rat skeletal muscle
- Alpha-lipoic acid as a dietary supplement: molecular mechanisms and therapeutic potential
- α-Lipoic acid: a multifunctional antioxidant that improves insulin sensitivity in patients with type 2 diabetes
- Alpha-lipoic acid as a biological antioxidant
- Antioxidant alpha-lipoic acid: a 7-month multicenter randomized controlled trial (ALADIN III Study). ALADIN III Study Group. Alpha-Lipoic Acid in Diabetic
- Effects of DL-alpha-lipoic acid on peripheral nerve conduction, blood flow, energy metabolism, and oxidative stress in experimental diabetic neuropathy
- alpha-Lipoic acid treatment decreases serum lactate and pyruvate concentrations and improves glucose effectiveness in lean and obese patients with type 2 diabetes.
- Alpha-lipoic acid: antioxidant potency against lipid peroxidation of neural tissues in vitro and implications for diabetic neuropathy
- Effects of alpha-lipoic acid on microcirculation in patients with peripheral diabetic neuropathy
- Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy.
Cissus Quadrangularis (Asthisamharaka)
- The effect of Cissus quadrangularis (CQR-300) and a Cissus formulation (CORE) on obesity and obesity-induced oxidative stress
- The use of a Cissus quadrangularis/Irvingia gabonensis combination in the management of weight loss: a double-blind placebo-controlled study
- The use of a Cissus quadrangularis formulation in the management of weight loss and metabolic syndrome
- Antioxidant and Antimicrobial Activity of Cissus quadrangularis L.
- Pharmacological actions of Cassia auriculata L. and Cissus quadrangularis Wall: A short review
- Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides
- Cissus quadrangularis stem alleviates insulin resistance, oxidative injury and fatty liver disease in rats fed high fat plus fructose diet
- Beneficial effect of Cissus quadrangularis Linn. on osteopenia associated with streptozotocin-induced type 1 diabetes mellitus in male Wistar rats
- Evaluation of the antidiabetic and antibacterial activity of Cissus sicyoides
- Cissus quadrangularis extract attenuates hyperglycaemia-mediated oxidative stress in streptozotocin-induced diabetic rats
- Effect of sesamin supplementation on cardiovascular risk factors in women with rheumatoid arthritis
- The sesame lignan sesamin attenuates vascular dysfunction in streptozotocin diabetic rats: involvement of nitric oxide and oxidative stress
- Sesame oil exhibits synergistic effect with anti-diabetic medication in patients with type 2 diabetes mellitus
- Antihypertensive effect of sesamin. IV. Inhibition of vascular superoxide production by sesamin
- Quercetin and sesamin protect neuronal PC12 cells from high-glucose-induced oxidation, nitrosative stress, and apoptosis
- Effects of vitamin E and sesamin on hypertension and cerebral thrombogenesis in stroke-prone spontaneously hypertensive rats
- Hypoglycaemic and hypolipidaemic activities of sesamin from sesame meal and its ability to ameliorate insulin resistance in KK‐Ay mice
- Effects of sesamin on streptozotocin (STZ)-induced NIT-1 pancreatic β-cell damage
- EFFECTS OF VITAMIN E AND SESAMIN ON HYPERTENSION AND CEREBRAL THROMBOGENESIS IN STROKE‐PRONE SPONTANEOUSLY HYPERTENSIVE
- Preventive effect of sesame seed cake on hyperglycemia and obesity against high fructose-diet induced Type 2 diabetes in rats
- Callophyllis japonica extract improves high-fat diet-induced obesity and inhibits adipogenesis in 3T3-L1 cells
- Anti-inflammatory effect of polyphenol-rich extract from the red alga Callophyllis japonica in lipopolysaccharide-induced RAW 264.7 macrophages
- Anti-obesity effect of Solidago virgaaurea extract in high-fat diet-fed SD rat
- Antioxidant activity of ethanol extract of Callophyllis japonica
- Investigation of the antiasthmatic properties of ethanol extract of Callophyllis japonica in mice
- Antioxidants from macroalgae: potential applications in human health and nutrition
- The radioprotective effects of the hexane and ethyl acetate extracts of Callophyllis japonica in mice that undergo whole body irradiation
- Effects of Callophyllis japonica powder on carbon tetrachloride-induced liver injury in rats
- A comparative study of radioprotection with Callophyllis japonica extract and amifostine against lethal whole body gamma irradiation in mice
- Immunomodulatory Effects of Callophyllis japonica Ethanol Extract on Dendritic Cells
Tangeritin (Citrus reticulata)
- Citrus bioactive phenolics: Role in the obesity treatment
- Citrus aurantium flavonoids inhibit adipogenesis through the Akt signaling pathway in 3T3-L1 cells
- Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese
- Effect of tangeretin, a polymethoxylated flavone on glucose metabolism in streptozotocin-induced diabetic rats
- Regulation of adipocytokine secretion and adipocyte hypertrophy by polymethoxyflavonoids, nobiletin and tangeretin
- Modulation of HepG2 cell net apolipoprotein B secretion by the citrus polymethoxyflavone, tangeretin
- Phenolic compositions and antioxidant capacities of Chinese wild mandarin (Citrus reticulata Blanco) fruits
- Studies on preparation of ready to serve mandarin (Citrus reticulata) diet drink
- Polymethoxylated, C-and O-glycosyl flavonoids in tangelo (Citrus reticulata× Citrus paradisi) juice and their influence on antioxidant properties
- Polymethoxyflavonoids tangeretin and nobiletin increase glucose uptake in murine adipocytes
- Arctigenin Inhibits Adipogenesis by Inducing AMPK Activation and Reduces Weight Gain in High‐Fat Diet‐Induced Obese Mice
- Arctigenin protects cultured cortical neurons from glutamate‐induced neurodegeneration by binding to kainate receptor
- Tumor specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L.
- Arctigenin efficiently enhanced sedentary mice treadmill endurance
- Comparative pharmacokinetics of arctigenin in normal and type 2 diabetic rats after oral and intravenous administration
- In vitro anti-inflammatory effects of arctigenin, a lignan from Arctium lappa L., through inhibition on iNOS pathway
- Immunomodulatory Effect of Arctigenin, a Lignan Compound, on Tumour Necrosis Factor‐α and Nitric Oxide Production, and Lymphocyte Proliferation
- Therapeutic effect of arctiin and arctigenin in immunocompetent and immunocompromised mice infected with influenza A virus
- Antiproliferative effect of arctigenin and arctiin
- Arctigenin, a phenylpropanoid dibenzylbutyrolactone lignan, inhibits MAP kinases and AP-1 activation via potent MKK inhibition: the role in TNF-α inhibition
Citrus Aurantium (Bitter Orange)
- Metabolic and physiological effects of ingesting extracts of bitter orange, green tea and guarana at rest and during treadmill walking in overweight males
- Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update
- A review of the human clinical studies involving Citrus aurantium (bitter orange) extract and its primary protoalkaloid p-synephrine
- Increase in the thermic effect of food in women by adrenergic amines extracted from citrus aurantium
- Citrus aurantium as a thermogenic, weight-reduction replacement for ephedra: an overview.
- Tissue lipid lowering-effect of a traditional Nigerian anti-diabetic infusion of Rauwolfia vomitoria foilage and Citrus aurantium fruit
- Effects of Citrus aurantium extract, caffeine, and St. John’s wort on body fat loss, lipid levels, and mood states in overweight healthy adults
- Thermic effect of Citrus aurantium in obese subjects
- Anxiolytic and sedative effects of extracts and essential oil from Citrus aurantium L.
- Antiobesity and cardiovascular toxic effects of Citrus aurantium extracts in the rat: a preliminary report
Pyrroloquinoline Quinone (PQQ) (Natto)
- Altering pyrroloquinoline quinone nutritional status modulates mitochondrial, lipid, and energy metabolism in rats
- Pyrroloquinoline quinone (PQQ) producing Escherichia coli Nissle 1917 (EcN) alleviates age associated oxidative stress and hyperlipidemia
- Pyrroloquinoline quinone stimulates epithelial cell proliferation by activating epidermal growth factor receptor through redox cycling
- Potential physiological importance of pyrroloquinoline quinone
- Pyrroloquinoline quinone, a novel protein tyrosine phosphatase 1B inhibitor, activates insulin signaling in C2C12 myotubes and improves impaired glucose
- Effects of dietary pyrroloquinoline quinone disodium on growth, carcass characteristics, redox status, and mitochondria metabolism in broilers
- Early PQQ supplementation has persistent long-term protective effects on developmental programming of hepatic lipotoxicity and inflammation in obese mice
- Pyrroloquinoline quinone ameliorates oxidative stress and lipid peroxidation in the brain of streptozotocin-induced diabetic mice
- Pyrroloquinoline quinone stimulates mitochondrial biogenesis through CREB phosphorylation and increased PGC-1α expression
- Pyrroloquinoline quinone prevents developmental programming of microbial dysbiosis and macrophage polarization to attenuate liver fibrosis in offspring of obese
Hesperidin (Citrus Cinsinensis osbeck)
- The hypoglycemic effects of hesperidin and naringin are partly mediated by hepatic glucose-regulating enzymes in C57BL/KsJ-db/db mice
- Effects of hesperidin on the progression of hypercholesterolemia and fatty liver induced by high-cholesterol diet in rats
- Oral intake of a combination of glucosyl hesperidin and caffeine elicits an anti-obesity effect in healthy, moderately obese subjects: a randomized double-blind
- Chemopreventive effects of diosmin and hesperidin on N‐butyl‐N‐(4‐hydroxybutyl)nitrosamine‐induced urinary‐bladder carcinogenesis in male ICR mice
- Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers
- Dietary hesperidin exerts hypoglycemic and hypolipidemic effects in streptozotocin-induced marginal type 1 diabetic rats
- Hypoglycemic and hypolipidemic effects of hesperidin and cyclodextrin-clathrated hesperetin in Goto-Kakizaki rats with type 2 diabetes
- Hesperidin prevents retinal and plasma abnormalities in streptozotocin-induced diabetic rats
- Antidiabetic effects of hesperidin and naringin in type 2 diabetic rats.
- Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases
- Antidiabetic effect of green rooibos (Aspalathus linearis) extract in cultured cells and type 2 diabetic model KK-Ay mice
- Hypoglycemic effect of aspalathin, a rooibos tea component from Aspalathus linearis, in type 2 diabetic model db/db mice
- Rooibos tea (Aspalathus linearis) partially prevents oxidative stress in streptozotocin-induced diabetic rats
- The cardioprotective effect of an aqueous extract of fermented rooibos (Aspalathus linearis) on cultured cardiomyocytes derived from diabetic rats
- Acute assessment of an aspalathin-enriched green rooibos (Aspalathus linearis) extract with hypoglycemic potential
- Effects of rooibos (Aspalathus linearis) on oxidative stress and biochemical parameters in adults at risk for cardiovascular disease
- Ameliorative effect of aspalathin from rooibos (Aspalathus linearis) on acute oxidative stress in Caenorhabditis elegans
- Aspalathin and Nothofagin from Rooibos (Aspalathus linearis) Inhibits High Glucose-Induced Inflammation In Vitro and In Vivo
- Modulation of antioxidant status in streptozotocin-induced diabetic male wistar rats following intake of red palm oil and/or rooibos
- Effects of rooibos tea extract on antigen-specific antibody production and cytokine generation in vitro and in vivo
Hibiscus (Hibiscus rosa-sinensis)
- An evaluation of the hypolipidemic effect of an extract of Hibiscus Sabdariffa leaves in hyperlipidemic Indians: a double blind, placebo controlled trial
- Development of functional beverages from blends of Hibiscus sabdariffa extract and selected fruit juices for optimal antioxidant properties
- Effect of Hibiscus sabdariffa on obesity in MSG mice
- Effects of Hibiscus sabdariffa extract powder and preventive treatment (diet) on the lipid profiles of patients with metabolic syndrome (MeSy)
- The effects of sour tea (Hibiscus sabdariffa) on hypertension in patients with type II diabetes
- Effect of Hibiscus rosa sinensis Linn. ethanol flower extract on blood glucose and lipid profile in streptozotocin induced diabetes in rats
- Hibiscus extract inhibits the lipid droplet accumulation and adipogenic transcription factors expression of 3T3-L1 preadipocytes
- Effect of Hibiscus sabdariffa L. Dried Calyx Ethanol Extract on Fat Absorption-Excretion, and Body Weight Implication in Rats
- Lipids lowering effect of Hibiscus rosa-sinensis flower petals on monosodium glutamate (MSG) induced obese rats
- Inhibition of angiotensin convertin enzyme (ACE) activity by the anthocyanins delphinidin-and cyanidin-3-O-sambubiosides from Hibiscus sabdariffa
- Capsaicin-like anti-obese activities of evodiamine from fruits of Evodia rutaecarpa, a vanilloid receptor agonist
- Anti-inflammatory and anti-infectious effects of Evodia rutaecarpa (Wuzhuyu) and its major bioactive components
- Evodia alkaloids suppress gluconeogenesis and lipogenesis by activating the constitutive androstane receptor
- Evodiamine: a novel anti-cancer alkaloid from Evodia rutaecarpa
- Effect of herbal Ephedra sinica and Evodia rutaecarpa on body composition and resting metabolic rate
- Inhibitory effect of rhetsinine isolated from Evodia rutaecarpa on aldose reductase activity
- The nociceptive and anti-nociceptive effects of evodiamine from fruits of Evodia rutaecarpa in mice
- The positive inotropic and chronotropic effects of evodiamine and rutaecarpine, indoloquinazoline alkaloids isolated from the fruits of Evodia rutaecarpa
- Anti-inflammatory effects and mechanisms of the ethanol extract of Evodia rutaecarpa and its bioactive components on neutrophils and microglial cells
- Novel anticholinesterase and antiamnesic activities of dehydroevodiamine, a constituent of Evodia rutaecarpa
- Anti-obesity effects of epigallocatechin-3-gallate, orange peel extract, black tea extract, caffeine and their combinations in a mouse model
- Antiobesity Effects of Chinese Black Tea (Pu‐erh Tea) Extract and Gallic Acid
- Antihypercholesterolemic effect of Chinese black tea extract in human subjects with borderline hypercholesterolemia
- Anti-hyperglycemic effect of black tea (Camellia sinensis) in rat
- The effect of an extract of green and black tea on glucose control in adults with type 2 diabetes mellitus: double-blind randomized study
- Modulatory effects of black v. green tea aqueous extract on hyperglycaemia, hyperlipidaemia and liver dysfunction in diabetic and obese rat models
- Glucose-lowering effect of powder formulation of African black tea extract in KK-Ay/TaJcl diabetic mouse
- Effect of Kombucha, a fermented black tea in attenuating oxidative stress mediated tissue damage in alloxan induced diabetic rats
- Effects on blood pressure of drinking green and black tea
- The effect of consuming instant black tea on postprandial plasma glucose and insulin concentrations in healthy humans
- Effects of Atractylodes macrocephala Koidzumi rhizome on 3T3-L1 adipogenesis and an animal model of obesity
- β-Eudesmol (a main component of Atractylodes lancea)-induced potentiation of depolarizing neuromuscular blockade in diaphragm muscles of normal and diabetic
- Studies on physico-chemical properties and hypoglycemic activity of complex polysaccharide AMP-B from Atractylodes macrocephala Koidz
- Stimulating effects on mouse splenocytes of glycoproteins from the herbal medicine Atractylodes macrocephala Koidz.
- Antioxidant ability and mechanism of rhizoma Atractylodes macrocephala
- Sesquiterpenoids from Atractylodes macrocephala act as farnesoid X receptor and progesterone receptor modulators
- Effects of Radish Seed, Dandelion and Atractylodes Macrocephala on Muscles of Stomach and Duodenum in Rabbit [J]
- The roots of Atractylodes macrocephala Koidzumi enhanced glucose and lipid metabolism in C2C12 myotubes via mitochondrial regulation
- The metabolism of polysaccharide from Atractylodes macrocephala Koidz and its effect on intestinal microflora
- Ethanol extract of Atractylodes macrocephala protects bone loss by inhibiting osteoclast differentiation
- Anti-obesity effect of Pinellia ternata extract in Zucker rats
- Pinellia ternata Breitenbach attenuates ovalbumin-induced allergic airway inflammation and mucus secretion in a murine model of asthma
- Effects of Pinellia ternata (Thunb.) Berit. on the metabolomic profiles of placenta and amniotic fluid in pregnant rats
- Effect of oral administration of Pinellia ternata, Zingiberis rhizoma and their mixture on the efferent activity of the gastric branch of the vagus nerve in the rat
- Transgenic Tobacco Expressing Pinellia ternata Agglutinin Confers Enhanced Resistance to Aphids
- Quantitative analysis of anti-emetic principle in the tubers of Pinellia ternata by enzyme immunoassay
- An anti-emetic principle of Pinellia ternata tuber
- Studies on Stimulating Components of Raw Pinellia ternata (Thunb.)(Banxia)
- Effect of Pinellia ternata tuber on the efferent activity of the gastric vagus nerve in the rat
- Effect of Pinellia ternata lectin on membrane currents of mouse motor nerve terminals
- Coptis chinensis alkaloids exert anti-adipogenic activity on 3T3-L1 adipocytes by downregulating C/EBP-α and PPAR-γ
- Anti-diabetic effect of Coptis Chinensis polysaccharide in high-fat diet with STZ-induced diabetic mice
- Anti-Diabetic Effects of a Coptis chinensis Containing New Traditional Chinese Medicine Formula in Type 2 Diabetic Rats
- Studies on the hypoglycemic effect of Coptis chinensis and berberine
- Hypoglycemic and Hypocholesterolemic Effects of Coptis chinensis Franch Inflorescence
- Antimicrobial properties of berberines alkaloids in Coptis chinensis Franch by microcalorimet
- Coptis chinensis Franch. exhibits neuroprotective properties against oxidative stress in human neuroblastoma cells
- Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation
- Antiinflammatory effects of a combined herbal preparation (RAH13) of Phellodendron amurense and Coptis chinensis in animal models of inflammation
- Neuroprotective Effect of Coptis chinensis in MPP and MPTP-Induced Parkinson’s Disease Models
- The Efficacy and Tolerability of Adjunctive Alternative Herbal Medicine (Salvia miltiorrhiza and Pueraria lobata) on Vascular Function and Structure in Coronary
- Effect of Salvia miltiorrhiza hydrophilic extract on antioxidant enzymes in diabetic patients with chronic heart disease: a randomized controlled trial
- Cardiovascular protective effects of adjunctive alternative medicine (Salvia miltiorrhiza and Pueraria lobata) in high-risk hypertension
- Extraction, preliminary structural characterization, and antioxidant activities of polysaccharides from Salvia miltiorrhiza Bunge
- Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion
- The protective effect of Salvia miltiorrhiza in an animal model of early experimentally induced diabetic nephropathy
- Constituents with α-glucosidase and advanced glycation end-product formation inhibitory activities from Salvia miltiorrhiza Bge.
- Inhibition of interleukin-12 and interferon-γ production in immune cells by tanshinones from Salvia miltiorrhiza
- Aqueous extract of Salvia miltiorrhiza attenuates increased endothelial permeability induced by tumor necrosis factor-α
- Effects of purified herbal extract of Salvia miltiorrhiza on ischemic rat myocardium after acute myocardial infarction
- Antihypertensive Effects of Gynura procumbens Extract in Spontaneously Hypertensive Rats
- Hypoglycemic effect of combination of Azadirachta indica A. Juss. and Gynura procumbens (Lour.) Merr. ethanolic extracts standardized by rutin
- Rice Cakes Containing Dietary Fiber Supplemented with or without Artemisia Annua and Gynura Procumbens Merr. Alleviated the Risk Factors of Metabolic
- Effects of an ethanolic extract of Gynura procumbens on serum glucose, cholesterol and triglyceride levels in normal and streptozotocin-induced diabetic rats
- Antidiabetic properties and mechanism of action of Gynura procumbens water extract in streptozotocin-induced diabetic rats
- Flavonoid identification and hypoglycaemic studies of the butanol fraction from Gynura procumbens
- Hypoglycemic and anti–hyperglycemic study of Gynura procumbens leaf extracts
- Antidiabetic effect of Gynura procumbens leaves extracts involve modulation of hepatic carbohydrate metabolism in streptozotocin-induced diabetic rats
- Hypoglycemic effects of Gynura procumbens fractions on streptozotocin-induced diabetic rats involved phosphorylation of GSK3β (Ser-9) in liver
- The effect of extraction temperature on total phenols and antioxidant activity of Gynura procumbens leaf
Higenamine Nelumbo nucifera (lotus seeds)
- Antiobesity and hypolipidemic effects of lotus leaf hot water extract with taurine supplementation in rats fed a high fat diet
- Ethanol extract of lotus (Nelumbo nucifera) root exhibits an anti-adipogenic effect in human pre-adipocytes and anti-obesity and anti-oxidant effects in rats fed a high
- Chemical constituents from Nelumbo nucifera leaves and their anti-obesity effects
- Higenamine 4′-O-β-D-glucoside in the lotus plumule induces glucose uptake of L6 cells through β2-adrenergic receptor
- Groups of Diabetic KK-CAy Mice Specifically Bred for High and Low Sensitivity to Exogenous Acetylcholine and β1-Adrenergic Stimulation: Interaction of Higenamine
- The relaxation effect and mechanism of action of higenamine in the rat corpus cavernosum
- Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acids and energy expenditure in human subjects
- Higenamine inhibits apoptosis and maintains survival of gastric smooth muscle cells in diabetic gastroparesis rat model via activating the β2-AR/PI3K/AKT pathway
- Higenamine reduces HMGB1 during hypoxia-induced brain injury by induction of heme oxygenase-1 through PI3K/Akt/Nrf-2 signal pathways
- Higenamine (Norcoclaurine) as stimulant and fat burner
Oleuropein
- Oleuropein attenuates visceral adiposity in high‐fat diet‐induced obese mice through the modulation of WNT10b‐ and galanin‐mediated signalings
- Effects of olive oil and its minor phenolic constituents on obesity-induced cardiac metabolic changes
- Evaluation of hypocholesterolemic effect of oleuropein in cholesterol-fed rats
- Oleuropein aglycone enhances UCP1 expression in brown adipose tissue in high-fat-diet-induced obese rats by activating β-adrenergic signaling
- Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases
- Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits
- Antidiabetic and Antioxidant Effects of Hydroxytyrosol and Oleuropein from Olive Leaves in Alloxan-Diabetic Rats
- Oleuropein offers cardioprotection in rats with simultaneous type 2 diabetes and renal hypertension
- Antihyperglycemic effect of thymoquinone and oleuropein, on streptozotocin-induced diabetes mellitus in experimental animals
- Hypoglycemic, hypolipidemic and antiatherogenic effects of oleuropein in alloxan-induced Type 1 diabetic rats
Warnings: As with any supplement, consult your medical practitioner prior to using this product if you are pregnant, may become pregnant, breastfeeding, taking medication, other dietary supplements or have a medical condition. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. *Daily Value has not been established.
Kristina –
I like this blend when I’m trying to drop a few lbs. Love ❤️ it! I get right back into the shape I want with this blend and a nice workout regimen. I also eat strict paleo during a shed phase 🙂 Also, look at all the yummy for your body nutrients in the blend!
Shanna Flint –
You want serious weight loss? Serious stamina to help you push through a workout with stable, relaxed, focused energy?? You want to literally watch the fat melt off of you and feel good while you’re doing it!?
Not to be super cheesy, but this is seriously the product for you, if you do.
I’m a busy single momma, raising my daughter on my own; trying to do it all. I work 50+ hours a week and bellydances twice a week. I don’t have time or money for bullshit that doesn’t work.
Let me just say… THIS …stuff …works. And it feels good in my body. There’s no jittery, hyper feeling. Only good, balanced stamina and power that lasts through my workout and beyond!!
I love this stuff.
Kim Martinez –
I love Thermo! I take a slightly heaping 1/4 teaspoon in the morning with my coffee and it cleans me out and gives me a steady euphoric smooth energy all day long. When I take it I find myself working dawn to dusk getting all kinds of stuff done around the house inside and out. It was real nice having it when I tilled and planted my garden! 🙂 I also add the scoop provided of Shilajit on some days. Also I seem to sleep better when taking it. Nebula is awesome too!
Matt Gonzalez –
I take this as part of my pre workout while in a fasted state, I can honestly say my body feels like it’s more in a burn mode than usual.
When taken on non workout days, I feel my body is more hungry than on days I don’t take it making me believe it’s burning more than normal. This is blend that I feel the most out of.
Phoebe (verified owner) –
I’ve tried most of Gavin’s blends and Thermo is by far my favorite (hmm to be fair Peel is a close second). It’s the holidays so I’ve been out at parties and gorging on unhealthy food, yet I haven’t gained a single pound ( even kept off the lbs I lost from my last fast) and the only thing Im taking consistenly is thermo everytime I eat something. You know that horrible nauseous feeling you get when youve been eating healthy and then you had one unhealthy meal (or when you break a fast with a burger), thermo will definitely make it go away. If I can only have just one blend from Gavin, I ll take just Thermo anyday!
Mary Nakamya –
With Thermo you get energy instantly and you wake up feeling refreshed, can’t trade it for anything.
Elysia Hartzell –
I began using Thermo along with Trinity to support myself in fasting to drop weight and heal my body. I had done some fasting prior to using the blends, and this was a game changer!!! Not only was fasting WAY easier, but the weight came off faster, I had more energy, and my mood drastically improved. I have lost over 30 pounds and have kept it off for several months now, even over the holidays when I let my eating and exercise habits slide. I have since added other blends such as Peel and Spice, and have been more than thrilled with every single one! Thank you so much Gavin for sharing these blends and your extensive knowledge!!
Carol (verified owner) –
Thermo has given me a lot more energy to last throughout each day, I climb stairs several times a day and was always tired by afternoon, since I started using Thermo, I am still bounding up and down the stairs until late afternoon! Thank you!
Anish –
Thermo was one of the first blends that I tried from Interstellar and is my favorite. I typically use in the morning mixed with Shilajit in tea which keeps going until the late afternoon. I have found that this helps when intermittent fasting and on the first day of an extended fast. I also like that there is data to support the use of the specific herbs in this blend.
Ariane Taylor (verified owner) –
I am doing IF 22/2 and it is SO much more sustainable with Thermo. My daily plan is now 1/2 tsp Thermo
1/4 tsp Trinity
1/4 tsp Peel
in a cup of tea 3xday.
With this, I am not counting the hours until I can eat again, I have an even mood and can go about my day without thinking too much about food
(although I definitely enjoy my meal when it comes around!)
Here are some things that have helped me (they may or may not apply to you):
1. I mix three blends (as above). It seems that every time I add a blend, my fasting gets easier. I add them one at a time, for about a week, to determine
the effect of each individual one. The next one I will add is spice. In my experience, this is definitely a positive addition to my life and health, but the
exact blends and amounts have to be tweaked individually.
2. At first, I was taking them once a day in the morning. Then I read that smaller servings taken several times a day are more effective. Sure enough, that
is true! I have not figured out how to dry fast while taking these blends, so my fasting is with tea with each serving.
3. To my taste, the blends are bitter (though not intolerably so). Morning and noon, I like to drink them with “Harney & Sons, Hot cinnamon spice black tea).
This neutralizes the bitterness a bit. In the evening, I mix them with Camomile tea, to favor a good night’s sleep. At any rate, the taste is an acquired
taste.
Best of luck to all who are researching this approach. The price of the blends is definitely covered by the smaller grocery and restaurant budget. So it is
like getting better health and a better body for free (dollar wise)!
[email protected] –
I’ve purchased a couple of different blends (along with getting few samples) & love them all. I really adore how Thermo makes me feel all warm & fuzzy inside. Along with the other blends I have energy like never before but this, SUPERNOVA & PEEL are my FAVES!
In the past three weeks, I’ve done mostly 88/8 and a couple 44/4 & 22/2 and I was able to drop more weight than ever all while feeling great.
I have the energy to workout dry fasted! My thoughts are so clear & my mind is so sharp. I don’t feel ANY hunger at all. Struggle with food is GONE! I look & feel better than I felt in years.
Most of all, I have a skin condition (annulare granuloma) which is starting to look so much better with less inflammation, less noticeable & I’m really HOPEFUL that the blends & dry fasting will help the appearance of my skin without steroids!
Friends & family are noticing the changes and starting to ask questions, I’m raving about these blends to EVERYONE! I was on the fence at first (I’m a total & utter skeptic) but I’m so thrilled I gave this a chance. LIFE CHANGING.
Aeona Staley –
I’ve been using Thermo and several other blends for almost two weeks. It was hard to narrow down which blends I wanted to try first. I chose Pine Pollen and Supernova. I was surprised to find several samples of other blends and was excited to use Thermo along with Trinity. I used both as fasting companions and noticed a bigger loss with one of my recent extended fasts. I deal with Fibro flareups and fatigue on a daily basis and have spent a considerable sum of money over these last 4.5 years, following the birth and postpartum hemorrhage with my youngest daughter, on trying to treat or remedy the chronic pain and fatigue. I’ve also dealt with low thyroid, though still dealing with other symptoms even while on natural dessicated t4/t3. I still get flareups and deal with fatigue and weight loss is on the slower side. I usually do 22:2 or 23:1 fast and extended 3-4 day fasts and these protocols have helped a lot. I was curious to see how these blends could help with my symptoms and improve my mental clarity and mood during extended fasts and even boost my losses. I really love the energized feeling I get when I take Thermo. I usually add it to black coffee or cacao nib drink. I’m currently doing another fast cycle and am continuing to take Thermo and Trinity and hope I continue seeing great results. I definitely need to order a larger size for continued use and my husband is interested in trying the blends.
Victoria –
I am 46 years old and was considered pre-diabetic at age 42. I am not overweight and I do cardio and weightlifting six days a week. I change my diet to attempt to deal with my elevated A1 C of 5.8. I was introduced to interstellar Blends. I initially tried the flavonoid peels. I began to feel a difference in my health and no longer felt sluggish. At this point I was dealing with early onset and sudden menopause. I am not sure if it’s a coincidence but my hot flashes stopped. I work very hard to maintain my weight so when I saw a thermo blend for weight loss on the site I decided to begin using that. I began to put it in my coffee every morning as well as in my 2nd cup of coffee later in the day.
I was able to maintain my weight without changing my diet and also maintain it through the holidays and too extensive vacations.
I was then introduced to intermittent fasting and I decided to use the thermo blends in conjunction with the fasting. I put the Thermo blend in my coffee in the morning and generally again in the afternoon. I follow a fasting schedule of 19/5. I only eat within that five hour window and the other 19 I have water Black Coffee and the thermal blend.
This past week when I got my blood work back I was so happy. Actually I was more like floored because I couldn’t believe that it all worked. My A1 C is down to 5.1 and I am no longer considered pre-diabetic. I honestly have no other explanation to why this happened other than the interstellar blends combined with the fasting. I tried for an entire year to lower my levels and nothing worked but these blends worked. I am completely through menopause without a single ounce of added weight gain. I am more toned and when I change my foods Within my eating window, I find it easier than ever to lose weight. I give these blends five stars.
Curran Coughlin –
I am doing 88/8 and let me tell you Thermo has surprised me so much! It gives you a positive well-being and very clean energy. It’s not like caffeine energy, and it doesn’t make you feel like you’re on a drug either. It gives you a positive drive with a energizing effect very forward moving per se. Absolutely love this, this is one of my personal favorites! This one and the seven sages are at the top of my list thank you so much Gavin for your awesome herbs 🙂
Tia Riki –
GAME CHANGER!!!
I’ve been taking 10-15 mile walks daily as a part of Gavin’s 88/8 challenge regiment and up to cylce 5 I was finding myself having very little trouble energy-wise completing my walks. Some leg and foot pain…but no real fatigue. But cycle 5 brought with it Mother Nature’s monthly calling card and with it a fatigue that blew the wind out of me…until Thermo.
I do my walks first thing in the morning when I work or have lots of things to do and even with the first recommended shot for the challenge I was finding myself dragging…having to stop and take 3 minute breaks dang near after every mile or so. Then came the second shot with Thermo.
I can’t even explain the night and day difference walking those first couple of miles without Thermo vs. walking the last couple of miles with it. I would take the shot…swish it around my mouth for 30 seconds as Gavin recommends…and I swear I would feel my whole body awaken almost instantly!
I’ve now added Thermo to EACH of my shots throughtout the day for the crazy clean energy it gives…and I’m ordering another Thermo for backup so that I never run out!!!
As a person who has suffered from low-energy ALL HER LIFE…with that time of the month being a particulaly debilitating time for me energy-wise…you have no idea how awesome it is to have something that gives me my life back the way Thermo does! There was a time I would literally have to call off from work during my cycle because of how incredibly fatigued I would be. To be able to go from that to being able to walk 10 miles during my cycle with ease…LIFE CHANGING!
Diana Beck –
I have always been health conscious but with the approach of my 60th birthday, I have really felt the need to step things up. I’ve been following a Keto/Paleo lifestyle for the last few years but my progress had stalled. My weight was stuck, my brain was stuck and my life felt stuck. I was really looking for something to kickstart new progress. I had been researching functional medicine, Chinese herbs and ayurvedic medicine when I saw a big black truck with an InterstellarPlan.com window decal. Naturally I was curious and was surprised to find it was exactly what I had been looking for. The coincidence was too much to ignore.
After some research I ended up purchasing Super Ultimate Sampler Pack with Spice and Peel. I was busy with packing and getting ready to move so at first I didn’t pay attention to any difference. After a few weeks of taking the blends I started to notice how my mood had improved, how I was much calmer and positive and felt more energetic. Then I noticed that when I got up in the morning my ankles wouldn’t pop for the first 5 minutes of walking and the dull ache in my hip had disappeared. These may not seem like huge changes but for someone who has been actively supplementing, exercising and trying to optimize their health for decades, this was big!
I’ve now been taking the blends for over two months and feel like I have found the tools to achieve great health. I especially love using Thermo for the great boost to my workouts and for the fact that it regulates my glucose levels. It helps me keep my weight in check and that’s a good thing.
Gavin seems to really want to help people and I feel good about supporting that!
Dana Beaurem –
MY ABSOLUTE FAVORITE. 2 weeks ago I started the 88/8 challenge. I had always been sn excercise junkie but struggled to get up to go the the gym and maintain a level of energy to get me tgrough my 10-12 hour work day but The blends started giving me that push on day. After my does of Thermi my energy level hit the roof; my energy was amazing.
In addition to Trinty, Nebula, Matcha, Spice, Peel, and Autophagy my life has changed. The energy, my mental clarity, my appearance, the way my skin feels abd glows,…I can go on. I couldn’t hsve made a better choice in my selection of the blends.
If anyone is on the fence abd feels skeptical; don’t be. The only thing you will lose is the old you. The feeling tired, obese bad skin, and any other ailments that has you in a slump. It sounds so funny to say but in less then 1 week I felt GREAT!! Try the sample packs and trust the processes you wint won’t regret a single decision ither than you procrastination to purchase the blends sooner.
If tgere was a t-shirt that I could buy that promotes Thermo I would wear to the gym during my 4am.workouts.
Thank you Gavin for you support in my selection and throughout my 88/8 and 66/6. I have now found what works for me.
Dana aka can’t live without my THERMO.
Molly (verified owner) –
The past few years, I found my energy declining. Once a marathoner, I lost all enthusiasm for running, as well as my commitment to follow a training plan. The less I moved, the more unwell I started becoming.. Food stopped being a fuel for the body that I had once control over, grazing became an all day, every day event. I had insatiable sugar cravings that I couldn’t resist. Just as unhealthy as the physical changes were the defense mechanisms I found myself developing to justify my not thriving … I had a lame excuse for everything! Still, I knew I was out of balance but any attempts I made to correct it were worthless. Motivational thinking, self help books are rather worthless when your physical self is out of whack.
Not recognizing myself, I made an appointment for a physical evaluation. I always had scalp psoriasis, now bloodwork revealed borderline Hashimotos (hypothyroid),. and many of my symptoms, brain fog and bloating, suggested celiac….all auto immune disorders. I was looking at a lifetime of pharmaceutical intervention.
Fortunately at that time, a friend reintroduced me to Interstellar, the original blend. Incredibly, it made it possible for me to commit to a 4 hour daily eating window. Within ten days I began noticing physical changes, scalp psoriasis GONE, my hair looked shiny and felt softer, my skin had a clearer quality, and most significantly, I stopped waking up just as tired as when i went to bed…I began to feel a return of energy!
I then decided to invest in Trinity and less than a month ago added Thermo. What I’m experiencing can only be described as FREEDOM. My thinking is clear and for the first in a long time I’m able to keep focused on my daily goals. The uncontrollable cravings for garbage food is gone. I’ve started running again and am building up mileage. Even in the Northeast winter weather, I am grateful for every mile I log…I’m feeling like quite a badass, lol. Not to mention, I lost 9 pound. I’m looking forward to my first fast this weekend.
Thank you for your work and product. The blends are restoring my freedom to live life to its fullest again.
Vlad Okel (verified owner) –
I ordered THERMO one month ago. It is my first time trying this stuff. I heard a lot about it from my friend but was hesitant to try it. I’m battling my blood sugar in pre-diabetes range. So I decided to give it a try.
I received my blend and started with 1/8 teaspoon dose. I was surprised to see results in three days! My fasting glucose level was about 20% lower! And I didn’t feel any discomfort or bloating in my stomach when I was taking the blend.
I am almost done with my pack now and getting ready to order more. I love the effect of THERMO and feel really good about taking this NATURAL supplement. I will try other products and definitely tell others about it. I already promised my friend a dinner for inspiring me to try it!
Alice Tyre (verified owner) –
This is the second blend I have used from Gavin (the first is autophagy which is amazing!! and i use it daily for dry fasting). Thermo is something special. I am 56 years old and literally feel 20 years younger.
I am doing 88/8 protocol. I did the first and second round with just autophagy blend. I walk 3 hours a day and, even as great as autophagy is, I would still find myself muddling through the last hour of that walk. So I came to the website and started searching for the next blend i would add that would maybe increase my energy during walking while fasting.
Enter Thermo! WOW! I take this in my second “shot” of the day, right before i head out to walk. And, I have to say that from the very first dose I could feel a difference. That third hour is now a breeze! And the first two go very much quicker, I am getting 10-11 mile walks in each day. I have no aches and pains and I just feel calm and relaxed while doing it. Just amazing
Ben Lévesque (verified owner) –
This product is really working well! I used this product and we can definitely see a big difference ! Use it during fasting and you will see awesome results very quick! Wow !
Ruth Miguel-Alleyne –
I started off using the Thermo, Matcha and Nebula blends with one of Gavin’s challenges. I was able to drop 22 lbs in four days(5months ago), and to this day have been able to keep off 15lbs. What i love most about the blends is that from practically the first use i felt a positive difference in my body. The blends were exceptional in providing the support i needed to avoid eating unhealthy foods and also to do my 10 mile walks. Before using the blends I would be extremely tired after my 4hr commute to and from work, the blends gave me energy to walk when I got home.
I was so impressed by the blends it didn’t take me long for me to rave to my friends about the positive difference I felt and they saw how I was better equipped to face the challenges of balancing work and family life. One of my friends decided to try the blend because of this and was so impressed that she once said to me she needed to figure out how to keep the blends as part of her daily routine for the rest of her life.
B.A. –
Thermo is such an amazing blend! If you’re interested in fitness of any kind, Thermo is a must-have in your arsenal. It’s packed with over 45 ingredients that support insulin recovery, fat burning, blood sugar regulation, longevity, energy, and mental focus.
The results are incredible! As soon as I take it, I feel this smooth jolt of energy – not jittery whatsoever. My body warms up and my appetite is suppressed. I feel sharp and focused. I also notice diuretic effects. So I’m often peeing like a racehorse, which is great for those who struggle with water retention issues like myself.
Lastly, dare I say that the taste isn’t bad at all. I take it in 1 oz shots of hot water (with Interstellar matcha) or 1 oz shots of espresso. Oftentimes, I mix in Interstellar shilajit for what I call my TURBO JET shot. It’s the best preworkout I’ve ever had – I take it fasted and it doesn’t make my stomach queasy like other preworkout drinks. It’s the cleanest fuel you’ll find to power your workouts – electrifying and charging your body in the best way.
C.S. –
Thermo works amazing for me! I was sceptical at first, but a friend talked me into it. I started taking Thermo when I started training again after a 4 month back injury. I started with a coach and I strictly logged it.
The first 3 months the goal was to lose fat, I was in a 10% caloric deficit with 4 workouts a week: I lost 13 pounds without losing any muscle. I went from 16.3% to 10.9% fat.
Then the following 3 months (till now) I changed it up in (in steps of 5% a week) to a 20% caloric surplus with 5 workouts a week, now I’m gaining muscle and still losing fat! I’m down to 9% fat now, while I gained 5 pounds of muscle (I’m a advanced trainee, so that’s a LOT!).
All I can say is: if you are a serious trainee I absolutely recommend Thermo in addition to your diet!
Shaya Lomax –
This blend has been working well for me. Got samples of this, trinity, and supernova and will take some with coffee or tea 2-3 times a day. If you follow the dry fasting schedules they really do work. I find myself not craving food as much and really not being drawn towards unhealthy snacks.
I take Thermo really as a pre-workout in the morning and afternoon and I really can see it working. I can push through my runs and have that extra drive that I haven’t had before. Its key to mixing well and not really put heavy cream in your drink because that basically ruins the purpose of the blends. I’ve gone down about 5 pounds being diligent with fasting, blends, and exercise over the past two weeks.
Mixing the blends has also helped clear up some brain fog that I’ve had before. In the past two years, I’ve felt the same kind of loneliness and sends of not doing anything important around this time of year. Taking the blends almost automatically puts me in a better mood and helps me stay focused on anything that I have to do in the day.
Dasha Mohlala –
This blend is my second favorite after SUPERNOVA… I cannot wait to order more of them both in bulk if my bank account allows (which it probably will because I’ll have saved so much from not needing to buy as many grocery hauls 😗😗✌🏽).
I take this before morning workouts in a fasted state with SUPERNOVA and time flies hah. After the second week of taking THERMO 3x a day in the recommended servings I looked like a different person in the mirror. I don’t weigh myself (haven’t in years) but the physical change was actually a shock to me. There’s not much more I can say about this blend because the results speak for themselves but this is a definite must try/buy if you’re wanting to lose or maintain weight without fad diets or too much change in your routine. It also just makes fasting a blissful experience.
Thank you again to Gavin for these blends – I’m looking forward to trying PINE POLLEN and NEBULA in my next batch along with the blends I’ve already tried!🔥🔥🔥
Erika Slim Valle –
Thermo became my absolute go to in the mornings. I take it on an empty stomach with hot water and then I take my morning coffee with some Trinity and get to work. That combo has made my mornings a mix of absolute bliss, focus and productivity. Absolute 5 star blend. I’m sure I will be taking my daily Thermo for years to come. Thanks Gavin!
L Kelly –
I Purchased the combo blend that included trinity and i must say how life changing the effects were. I run 2 companies and play full time football my life is hectic i suffer with anxiety a lot and so does my mum, since starting these blends i have had more energy and focus and little to no anxiety plus the physical benefits for football have been amazing better cardiovascular results and muscle definition. I want to thank this company so so much and iv recommended to literally everyone i know such a small price to pay for the benefits
Rich Ryan –
Thermo really helps me avoid that sugar hit and crash when I eat dessert. Also helps keep my blood pressure down. And if you’re fasting, it’s the perfect blend to fast with as well. It really helps to burn the fat off as fast as possible! Combine with walking or light cardio for best results!
Stephen Redding –
We have tried almost every product from this shop.. Thermo has become a staple for me and my girl. We look at it sort of like a fat burner. But what is great about Thermo is it does what fat burners do , only more effectively , without the jitters!
We can feel it warming us up, literally. Thermo totally lives up to it’s name. It seems to melt away our mid sections. We had taken a break from it for a few months and admittedly due to our food choices noticed some fat returning around our mid-sections. This stuff works and works quickly. Within about two weeks of using Thermo (we also combined it with Seven Sages and trinity) our clothes were fitting more comfortable again and about a month or so into this now we are still seeing results and still sliming down.
Another thing I like about Thermo is it warms me up so much , that cold weather is more enjoyable. I found myself not needing to grab a jacket in the morning and just heading out for work. So it’s really warming but not to the point it makes me uncomfortable, even in warmer weather. We just took a family trip to Florida and were in the sun and at the beach a good deal and were still ritually taking our Thermo.
My girl and I have come to really enjoy the warming effects from this blend. It really stands out to us even when combining with other blends. Thanks Gavin!
Nicole Rodriguez (verified owner) –
Ever since I had kids, I have been overweight & have struggled to lose weight. I also used food as a crutch and was not eating or living the healthiest lifestyle. I was introduced to interstellar blends from a friend and, for several months, I tried just the Thermo blend. I lost 15 lbs with this fantastic blend on its own, and then I started to branch out to try other combinations with Thermo.
I added Trinity, Autophagy, Senolytic, Anti-Adipogenic, and most recently, I added Super Sonic hair. I have lost 30 lbs in 4 weeks with these fantastic blends while also following a strict keto diet. I also do not crave sugar or sweets as I did before, which has been a tremendous change in my life. To say these blends have been a miracle in my life is not an exaggeration.
Losing weight in my 30’s has been challenging, and now that I have hit my 40’s, I am looking forward to enjoying the athletic & lean body I had pre-kids and seeing food for its nutritional value and not as a coping mechanism. Thank you, interstellar blends, for changing my life.
Rosie Kisun –
I tried Interstellar herbs a few years back only having tried Trinity and loved it! It was like magic in a bottle (bag). Due to financial constraints I couldn’t continue but promised myself that when I was ready that these herbs would be a part of my daily routine.
I’ve been taking Thermo for a week now, combined with Spice and Peel and can already notice the different it’s making with increased energy, more focus, clarity and overall well being. I’m motivated to get through my extensive to-do list without it being a chore.
I also deal with a little anxiety and have found this week to be more cruisy. These herbs are a god send!
Ray (verified owner) –
I take Thermo as part of my pre-workout while in a fasted state, I can honestly say my body feels like it’s more in a burn mode than usual. With Thermo you get energy instantly and you wake up feeling refreshed, can’t trade it for anything.
This product is amazing and does wonders to your body. Definitely use it during fasting and will see more results.
Thank you for creating such an amazing Blend.
Paul (verified owner) –
A couple years ago, I went to help my sister move house. At the time, I looked like a beanpole and was recovering from some pretty rotten heart issues (to which all of the blends I’ve used have been amazing and life saving—literally, I didn’t think I would live to see 35; now it’s only a few months away, and I know I’ll be fine!). Somedays, it was a miracle I could even get out of bed, somedays, the miracle didn’t come. It was a dark time, but I was slowly getting better and was starting to have more good days than bad, thanks to the blends. Only problem was, I’d run out of the the typical blends I used to help me with my heart issues, and so I was prepared for the worst.
What I didn’t expect was for Thermo to help energize me so much.
Now, you might be wondering why I used Thermo when I was a beanpole, and the reason was, was because I’d trusted Gavin’s products, and I needed the energy and strength boost, and Thermo had given my wife a lot of energy during her crazy work schedule. So I decided to try it, and I was alert and awake and feeling well enough to go help my sister move.
It was pretty grueling, as house moves can be, but I was strong, despite the heart issues. My sister said “Dang, Paul, I didn’t know you were such a muscle man!” I said, “You should see me on all the blends.”
Since then, Thermo has pretty much been a staple. I’ve noticed it pairs exceptionally well with several of the blends, and if you want a pre-workout rush—Thermo, Trinity, Supernova—mind-blown. One of my favorites is Thermo and Autonomous blended together—beautiful clarity, and high-quality creative thought.
I can’t take it with coffee because my heart goes crazy, (sounds like AFib, but it’s not), but I can take it with cacao, or just by itself (or with the other blends). And maybe this is cheating, but I do take it with stevia, and I’m still reaping the benefits.
For me, it works best in small doses a few hours apart, and I don’t take it after 3:00 pm.
And just like the name, I feel warmer when I take it. It’s butt cold where I live (as of writing this in early March, it’s literally -22 with the windchill!), and if I’ve got stuff to do outside, Thermo helps me stay warm.
It also helps me not get the dad-pudge—even when I’m not working out and eating more than I know I should (don’t get me wrong, I typically eat pretty clean, but you know how it goes sometimes, and I’ve also found if I don’t eat enough sugars, I literally can’t sleep, so sometimes I over-eat). But when I do workout, it’s almost like I can synthesize protein better because I start packing on the muscle easier.
I love this stuff. Highly recommended.
Amanda Collins (verified owner) –
Thermo is the best blend for losing weight! I lost 20 pounds in 2 months, by just fasting and without even working out. I can’t believe how fast the weight fell off. I have so much energy now too from taking blends daily. I feel stronger mentally and psychically!
Fabiola (verified owner) –
Thermo is my favorite blend before the workout. I sweat a lot, and I feel more energetic.
I drink it with coffee before the workout and then two more times during the day.
It helps me to drop those last pounds that are hard to loose, and it also helps me to fast longer without feeling hungry. Bonus: I like hoe it tastes when I drink it in hot water.
Ronald (verified owner) –
I LOVE THIS BLEND ITS ONE MY NEW FAV BLENDS
IT HAS HELPED TO LOSE SOME STUBBORN BELLY FAT ALONG WITH GAINZ WHICH IS ANOTHER AMAZING BLEND
WHICH I HIGLY SUGGEST
Nikita Petko –
We’ve experimented with nearly every product available at this store. Thermo has become a must-have for both my partner and me, serving as our go-to fat burner. What sets Thermo apart is its ability to achieve the effects of fat burners, but with enhanced effectiveness and without any jittery sensations.
The warming sensation it provides is quite noticeable. Thermo truly lives up to its name, seemingly melting away excess weight, especially around our midsections. After taking a break for a few months and noticing some return of fat due to dietary choices, we resumed Thermo use. The results were swift – within about two weeks, combined with Seven Sages and Trinity, our clothes fit more comfortably. Even a month into the routine, we continue to see positive changes, steadily slimming down.
One aspect we appreciate about Thermo is the comforting warmth it imparts, making cold weather more enjoyable. I’ve found myself skipping the morning jacket routine for work, thanks to the cozy warmth Thermo provides. Remarkably, it doesn’t become uncomfortably hot, even in warmer weather. During a recent family trip to Florida, we continued our Thermo regimen, enjoying the sun and beach without missing a beat.
My partner and I have grown to truly relish the warming effects of this blend, which stands out even when combined with other blends. Thank you, Gavin, for a product that has genuinely made a positive impact on our well-being!
George –
Interstellar Blends is a company that offers a range of high-quality health supplements that are designed to help people achieve their fitness goals. I have personally tried three of their products – Rewire, Trinity, and Thermo – and I must say that I am highly impressed with the results. Not only have these products helped me with my fasting and weight loss journey, but they have also improved my overall feeling of well-being.
Rewire is a cognitive enhancer that contains a blend of natural nootropics that improve focus, memory, and mental clarity. It helped me stay on track with my fasting regimen and avoid mindless snacking during my feeding windows. Trinity, on the other hand, is a powerful blend of three potent herbs that support healthy digestion and improve gut health. It helped me feel lighter and more energized, especially during longer fasts. Lastly, Thermo is a thermogenic fat burner that helped me shed excess body fat and achieve my weight loss goals faster.
Overall, I would highly recommend Interstellar Blends to anyone looking for a natural and effective way to support their health and fitness goals. Their products are of the highest quality, and they offer a range of benefits that go beyond just weight loss and fasting. Whether you are looking to improve your cognitive performance, gut health, or energy levels, Interstellar Blends has something for you.