NEBULA

200:1 CONCENTRATION

INTERSTELLAR BLEND

NEBULA
THIS IS AS STRONG AS IT GETS! 

4 TIMES STRONGER THAN SUPERNOVA.
10 TIMES STRONGER THAN ORIGINAL.
1/8 teaspoon 200:1 = 25 teaspoons 1:1

(300 1/8 tsp .83 a serving per bag 100g)

NEBULA IS RAW POWER AND PRESENCE. TOTAL CONFIDENCE.
​ANXIETY DECIMATOR. MOTIVATIONAL ROCKET FUEL.
DOSAGE IS 1/8 TEASPOON (best taken preworkout)

BLEND INGREDIENTS

​Reishi
“THE MUSHROOM OF IMMORTALITY” Liver Regeneration, Neuroprotector, Anti Cancer, AMPK activator, mTOR inhibitor

1. ReishiMax, mushroom based dietary supplement, inhibits adipocyte differentiation, stimulates glucose uptake and activates AMPK
2. How Reishi Combats Aging
3. How Lingzhi Mushrooms (Reishi) Combats Aging, Disease and Cancer
4. Anti-Tumor Effects of Ganoderma lucidum (Reishi) in Inflammatory Breast Cancer in In Vivo and In Vitro Models
5. Ganoderma lucidum (Reishi) suppresses proliferation and migration of breast cancer cells via inhibiting Wnt/β-catenin signaling
6. Abstract 5556: Enhancing response of Ganoderma lucidum (Reishi) and lapatinib in HER2+ inflammatory breast cancer cells
7. Abstract 1992: Ganoderma lucidum (Reishi) induces autophagy in inflammatory breast cancer by regulation of the mTOR signaling pathway
8. Abstract 1987: Ganoderma lucidum (Reishi) suppresses key protein synthesis initiation molecules in inflammatory breast cancer
9. Abstract 4228: Ganoderma lucidum (Reishi) reduces inflammatory breast cancer progression via protein synthesis inhibition
10. Abstract 3212: Ganoderma lucidum (Reishi) chemosensitizes EGFR-overexpressing inflammatory breast cancer cells to erlotinib
11. Anti-Amnesic Effect of Fermented Ganoderma lucidum Water Extracts by Lactic Acid Bacteria on Scopolamine-Induced Memory Impairment in Rats
12. Sporoderm-Broken Spores of Ganoderma lucidum Inhibit the Growth of Lung Cancer: Involvement of the Akt/mTOR Signaling Pathway
13. Evaluation of in vivo antioxidant activities of Ganoderma lucidum polysaccharides in STZ-diabetic rats
14. Antihyperglycemic Effect of Ganoderma Lucidum Polysaccharides on Streptozotocin-Induced Diabetic Mice
15. Anti-diabetic effects of Ganoderma lucidum
16. International Journal of Medicinal Mushrooms
17. Hypoglycemic effects of Ganoderma lucidum polysaccharides in type 2 diabetic mice
18. Antagonizing β-amyloid peptide neurotoxicity of the anti-aging fungus Ganoderma lucidum
19. Neuroprotective effect of preadministration with Ganoderma lucidum spore on rat hippocampus
20. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer’s Disease
21. Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota
22. Ganoderma lucidum, a new prebiotic agent to treat obesity?
23. Corrigendum: Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota
24. Hypoglycemic effect and mechanism of a proteoglycan from Ganoderma Lucidumonstreptozotocin-induced type 2 diabetic rats
25. Triterpenes From Ganoderma Lucidum Induce Autophagy in Colon Cancer Through the Inhibition of p38 Mitogen-Activated Kinase (p38 MAPK)
26. Recombinant Lz-8 from Ganoderma lucidum induces endoplasmic reticulum stress-mediated autophagic cell death in SGC-7901 human gastric cancer cells
27. Anti-cancer properties of triterpenoids isolated from Ganoderma lucidum – a review
28. Methanolic Extract of Ganoderma lucidum Induces Autophagy of AGS Human Gastric Tumor Cells
29. Antidepressant-like effects of a water-soluble extract from the culture medium of Ganoderma lucidum mycelia in rats
30. Ganoderma lucidum Protects Dopaminergic Neuron Degeneration through Inhibition of Microglial Activation

​Gynostemma
“THE HERB OF IMMORTALITY” Combats Aging, Strengthens Heart, Lifts Spirits, AMPK activator

1. Gynostemma pentaphyllum Tea Improves Insulin Sensitivity in Type 2 Diabetic Patients
2. New dammarane-type glucosides as potential activators of AMP-activated protein kinase (AMPK) from Gynostemma pentaphyllum
3. Heat-processed Gynostemma pentaphyllum extract improves obesity in ob/ob mice by activating AMP-activated protein kinase
4. Antiobesity effect of Gynostemma pentaphyllum extract (actiponin): A randomized, double‐blind, placebo‐controlled trial
5. Potential Hypoglycemic Effect of an Ethanol Extract of Gynostemma pentaphyllum in C57BL/KsJ-db/db Mice
6. Chemical constituents from a Gynostemma laxum and their antioxidant and neuroprotective activities
7. Inhibitory Effect of Damulin B from Gynostemma pentaphyllum on Human Lung Cancer Cells
8. The Effect of Gynostemma Pentaphyllum Extract on DNA Damage of Aging Rats
9. Anti-Oxidative Effect of Gynostemma and Hawthorn Extracts on the Aging Mouse Model Induced by D-galactose
10. Gynostemma pentaphyllum Exhibit Differential Induction of Cell Cycle Arrest in H460 and A549 Cancer Cells
11. [A preliminary observation of preventive and blocking effect of Gynostemma pentaphyllum (Thunb) Makino on esophageal cancer in rats].
12. Anti-cancer effects of Gynostemma pentaphyllum (Thunb.) Makino (Jiaogulan)
13. EFFECTS OF GYNOSTEMMA PENTAPHYLLUM MAKINO ON THE IMMUNOLOGICAL FUNCTION OF CANCER PATIENTS
14. Antidiabetic Effect of Gynostemma pentaphyllum Tea in Randomly Assigned Type 2 Diabetic Patients[*]
15. Herbal Extract of Gynostemma Pentaphyllum Decreases Hepatic Glucose Output in Type 2 Diabetic Goto-Kakizaki Rats
16. Hypoglycemic Activity of Polysaccharide from Gynostemma pentaphyllum on Type 2 Diabetic Rats and its Mechanism
17. Two Novel Anti-Inflammatory 21-Nordammarane Saponins from Tetraploid Jiaogulan (Gynostemma pentaphyllum)
18. Phytopreventative Anti-Hyperlipidemic Effects Of Gynostemma Pentaphyllum In Rats
19. Gynostemma pentaphyllum exhibits anti-inflammatory properties and modulates antimicrobial peptide expression in the urinary bladder
20. Gypenoside L, Isolated from Gynostemma pentaphyllum, Induces Cytoplasmic Vacuolation Death in Hepatocellular Carcinoma Cells through Reactive-Oxygen-Species-Mediated Unfolded Protein Response
21. Isolation and antitumor activities of acidic polysaccharide from Gynostemma pentaphyllum Makino
22. Chemical Composition of Five Commercial Gynostemma pentaphyllum Samples and Their Radical Scavenging, Antiproliferative, and Anti-inflammatory Properties
23. Two new saponins from tetraploid jiaogulan (Gynostemma pentaphyllum), and their anti-inflammatory and α-glucosidase inhibitory activities
24. Long-term oral administration of Gynostemma pentaphyllum extract attenuates airway inflammation and Th2 cell activities in ovalbumin-sensitized mice
25. Characterization of a Novel Alkali-Soluble Heteropolysaccharide from Tetraploid Gynostemma pentaphyllum Makino and Its Potential Anti-inflammatory and Antioxidant Properties
26. Neuroprotective Effects of Herbal Ethanol Extracts from Gynostemma pentaphyllum in the 6-Hydroxydopamine-Lesioned Rat Model of Parkinson’s Disease
27. Anxiolytic Effects of Herbal Ethanol Extract from Gynostemma pentaphyllum in Mice after Exposure to Chronic Stress
28. Preconditioning of brain slices against hypoxia induced injury by a Gynostemma pentaphyllum extract – Stimulation of anti-oxidative enzyme expression
29. Protective effects of crude polysaccharide from Gynostemma pentaphyllum on swimming exercise-induced oxidative stress in rat.
30. Antidepressant Activities of Extracts from Gynostemma pentaphyllum(Thunb.) Makino

Shilajit
“DESTROYER OF WEAKNESS” Contains All Trace Minerals & the Critical Fulvic Acid – 2nd only to DNA in Importance

1. Anti-Inflammatory and Anti-Arthritic Efficacy and Safety of Purified Shilajit in Moderately Arthritic Dogs
2. Shilajit attenuates streptozotocin induced diabetes mellitus and decrease in pancreatic islet superoxide dismutase activity in rats
3. Can Nutraceuticals Prevent Alzheimer’s Disease? Potential Therapeutic Role of a Formulation Containing Shilajit and Complex B Vitamins
4. EFFECTS OF SHILAJITON MEMORY, ANXIETY AND BRAINMONOAMINES IN RATS
5. Effects of shilajit and its active constituents on learning and memory in rats
6. Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
7. Shilajit: A Humic Matter Panacea for Cancer
8. Shilajit attenuates streptozotocin induced diabetes mellitus and decrease in pancreatic islet superoxide dismutase activity in rats
9. Effect of shilajit on blood glucose and lipid profile in alloxan-induced diabetic rats
10. Shilajit‐induced potentiation of the hypoglycaemic action of insulin and inhibition of streptozotocin induced diabetes in rat
11. Phenolic antioxidant-chromium complexes for treatment or prevention of type 2 diabetes or glucose intolerance
12. Effect of Shilajit on the Levels of Pro-inflammatory and Anti-inflammation Cytokines in Hepatic Injury in Male Rats
13. Oxidative Stress Induced by Lead and Antioxidant Potential of Certain Adaptogens
14. Chemistry of shilajit, an immunomodulatory Ayurvedic rasayan
15. Antiepileptic and antipsychotic activities of standardized Śilājatu (Shilajit) in experimental animals
16. Glycine- and GABA-mimetic Actions of Shilajit on the Substantia Gelatinosa Neurons of the Trigeminal Subnucleus Caudalis in Mice
17. Effect of Shilajit enriched diet on immunity, antioxidants, and disease resistance in Macrobrachium rosenbergii (de Man) against Aeromonas hydrophila
18. Effect of Shilajit on body weight of young rats
19. Method for treating pain and inflammation associated with arthritis using chromium-three cation in combination with phyllanthus emblica and shilajit
20. Standardization and Anti-Inflammatory Activity of Shilajit

​Chaga
​”DIAMOND OF THE FOREST” ” THE GIFT FROM GOD” Super Antioxidant, Supports Overall Health, Anti Stress, Anti Aging

1. Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice
2. Suppression of Adiposity and Improvement of Fat Metabolism in High-fat Diet-induced Obese Mice Treated with an Inonotus obliquus Extract [2016]
3. Improvement of Lipid Metabolism of Inonotus obliquus and roasted Inonotus obliquus extracts in mice a fed high-fat diet
4. Medicinal Mushrooms and Cancer
5. Anti-cancer effect and structural characterization of endo-polysaccharide from cultivated mycelia of Inonotus obliquus
6. Optimization of ultrasonic/microwave assisted extraction (UMAE) of polysaccharides from Inonotus obliquus and evaluation of its anti-tumor activities
7. Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus
8. Antitumor activity of water extract of a mushroom, Inonotus obliquus, against HT‐29 human colon cancer cells
9. Lanostane-type triterpenoids from the sclerotia of Inonotus obliquus possessing anti-tumor promoting activity
10. Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells
11. Anti-inflammatory and anticancer activities of extracts and compounds from the mushroom Inonotus obliquus
12. Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer
13. Anti-diabetic effects of Inonotus obliquus polysaccharides-chromium (III) complex in type 2 diabetic mice and its sub-acute toxicity evaluation in normal mice
14. Hypoglycemic and Antioxidative Effects of Fermented Chaga Mushroom (Inonotus obliquus) on Streptozotocin-induced Diabetic Rats
15. Anti-diabetic effects of Inonotus obliquus polysaccharides in streptozotocin-induced type 2 diabetic mice and potential mechanism via PI3K-Akt signal pathway
16. Protective Effect of Polysaccharides from Inonotus obliquus on Streptozotocin-Induced Diabetic Symptoms and Their Potential Mechanisms in Rats
17. Amelioration of scopolamine induced cognitive dysfunction and oxidative stress by Inonotus obliquus – a medicinal mushroom
18. Oxidative stress response of Inonotus obliquus induced by hydrogen peroxide
19. In Vitro investigation on antioxidative effect of Inonotus obliquus extracts against oxidative stress on PC12 cells
20. Antidiabetic activities of polysaccharides separated from Inonotus obliquus via the modulation of oxidative stress in mice with streptozotocin-induced diabetes
21. Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice
22. Anti-Obesity Activity, Anti-Cancer Activity and Single Oral Dose Toxicity of Inonotus xeranticus Extracts
23. Insulin‐Sensitizing and Beneficial Lipid‐Metabolic Effects of the Water‐Soluble Melanin Complex Extracted from Inonotus obliquus
24. Identification of Inonotus obliquus and Analysis of Antioxidation and Antitumor Activities of Polysaccharides
25. Inonotus obliquus protects against oxidative stress-induced apoptosis and premature senescence
26. Anti-inflammatory effect of Inonotus obliquus, Polygala senega L., and Viburnum trilobum in a cell screening assay
27. Anti-Oxidant and Anti-Inflammatory Activities of Inonotus obliquus and Germinated Brown Rice Extracts
28. Pleurotus tuber-regium Polysaccharides Attenuate Hyperglycemia and Oxidative Stress in Experimental Diabetic Rats
29. [Triterpenoids from Inonotus obliquus protect mice against oxidative damage induced by CCl4].
30. Chaga mushroom extract inhibits oxidative DNA damage in lymphocytes of patients with inflammatory bowel disease

Eleuthero
“SIBERIAN GINSENG” Memory Booster, Anti Stress & Fatigue

1. Assessing the Anticancer Potential of NaturalHealth Products (Lemongrass, Hibiscus, andEleuthero Ginseng) Against Breast Cancer Models
2. EFFECTS OF SIBERIAN GINSENG (ELEUTHEROCOCCUS SENTICOSUS MAXIM.) ON ELDERLY QUALITY OF LIFE: A RANDOMIZED CLINICAL TRIAL
3. Eleutherococcus senticosus reduces cardiovascular stress response in healthy subjects: a randomized, placebo‐controlled trial
4. The Effect of Siberian Ginseng (Eleutherococcus Senticosus) on Substrate Utilization and Performance during Prolonged Cycling
5. The influence of active components of Eleutherococcus senticosus on cellular defence and physical fitness in man
6. Hypoglycemic Effect of Syringin from Eleutherococcus senticosus in Streptozotocin-Induced Diabetic Rats
7. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice
8. Increase of β-Endorphin Secretion by Syringin, an Active Principle of Eleutherococcus senticosus, to Produce Antihyperglycemic Action in Type 1-like Diabetic Rats
9. Anti-diabetic and Hypoglycemic Effect of Eleutherococcus spp.
10. MICROWAVE‐ASSISTED SEED ESSENTIAL OIL OF ELEUTHEROCOCCUS SENTICOSUS AND ITS ANTIOXIDANT AND FREE RADICAL‐SCAVENGING ACTIVITIES
11. Release of acetylcholine by syringin, an active principle of Eleutherococcus senticosus, to raise insulin secretion in Wistar rats
12. Eleutheroside E, An Active Component of Eleutherococcus senticosus, Ameliorates Insulin Resistance in Type 2 Diabetic db/db Mice
13. Hypoglycemic Effect of Syringin from Eleutherococcus senticosus in Streptozotocin-Induced Diabetic Rats
14. The Effect of Eight Weeks of Supplementationwith Eleutherococcus senticosus on EnduranceCapacity and Metabolism in Human
15. Increase of β-Endorphin Secretion by Syringin, an Active Principle of Eleutherococcus senticosus, to Produce Antihyperglycemic Action in Type 1-like Diabetic Rats
16. A Herbal Composition of Scutellaria baicalensis and Eleutherococcus senticosus Shows Potent Anti-Inflammatory Effects in an Ex Vivo Human Mucosal Tissue Model
17. Effect of light on oxidative stress, secondary metabolites and induction of antioxidant enzymes in Eleutherococcus senticosus somatic embryos in bioreactor
18. Isolation and Hypoglycemic Activity of Eleutherans A, B, C, D, E, F, and G: Glycans of Eleutherococcus senticosus Roots
19. Siberian ginseng (Eleutherococcus senticosus): current status as an adaptogen [1985]
20. Differential antioxidant and quinone reductase inducing activity of American, Asian, and Siberian ginseng

Rhodiola
​”THE GOLDEN ROOT” Mood Enhancer, Combats Anxiety & Depression, mTOR inhibitor

1. Rhodiola crenulata extract suppresses hepatic gluconeogenesis via activation of the AMPK pathway
2. Rhodiola crenulata extract regulates hepatic glycogen and lipid metabolism via activation of the AMPK pathway
3. Rhodiola rosea extracts and salidroside decrease the growth of bladder cancer cell lines via inhibition of the mTOR pathway and induction of autophagy
4. Protective Effects of Rhodiola Crenulata Extract on Hypoxia-Induced Endothelial Damage via Regulation of AMPK and ERK Pathways
5. Rhodiola crenulata Attenuates γ-Ray Induced Cellular Injury via Modulation of Oxidative Stress in Human Skin Cells
6. Antioxidative Effects of Rhodiola Genus: Phytochemistry and Pharmacological Mechanisms against the Diseases
7. Rhodiola rosea L.: an Herb with Anti-Stress, Anti-Aging, and Immunostimulating Properties for Cancer Chemoprevention
8. Rhodiola crenulata inhibits Wnt/β-catenin signaling in glioblastoma
9. Rosenroot (Rhodiola): Potential Applications in Aging-related Diseases
10. Rhodiola: A Promising Anti-Aging Chinese Herb
11. Study of anti-aging and anti-dementia effects of Rhodosin on aging rats and experimental dementia rats
12. Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses
13. Rhodiola algida improves chemotherapy-induced oral mucositis in breast cancer patients
14. The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer (experimental clinical research)
15. Rhodiola crenulata Induces Death and Inhibits Growth of Breast Cancer Cell Lines
16. Free radical scavenging property and antiproliferative activity of Rhodiola imbricata Edgew extracts in HT-29 human colon cancer cells
17. Rhodiola crenulata induces an early estrogenic response and reduces proliferation and tumorsphere formation over time in MCF7 breast cancer cells
18. Aqueous extract of Rhodiola imbricata rhizome inhibits proliferation of an erythroleukemic cell line K-562 by inducing apoptosis and cell cycle arrest at G2/M phase
19. Effect of Rhodiola on nude mice with human breast cancer xenografts
20. The effect of Rhodiola kirilowiiextracts ontumor-induced angiogenesis in mice
21. Evaluation of Rhodiola crenulata and Rhodiola rosea for management of Type II diabetes and hypertension.
22. Anti-Diabetes Functionality of Kefir Culture-Mediated Fermented Soymilk Supplemented with Rhodiola Extracts
23. Rhodiola crenulata root ameliorates derangements of glucose and lipid metabolism in a rat model of the metabolic syndrome and type 2 diabetes
24. Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice
25. Citrus aurantium and Rhodiola rosea in combination reduce visceral white adipose tissue and increase hypothalamic norepinephrine in a rat model of diet-induced obesity
26. [Investigation of a compound, compatibility of Rhodiola crenulata, Cordyceps militaris, and Rheum palmatum, on metabolic syndrome treatment II – improving obesity].
27. Evaluation of Rhodiola rosea supplementation on skeletal muscle damage and inflammation in runners following a competitive marathon
28. Early use of Chinese drug rhodiola compound for patients with post-trauma and inflammation in prevention of ALI/ARDS
29. In vitro protective effect of Rhodiola rosea extract against hypochlorous acid-induced oxidative damage in human erythrocytes
30. [Effects of Rhodiola rosea on level of 5-hydroxytryptamine, cell proliferation and differentiation, and number of neuron in cerebral hippocampus of rats with depression induced by chronic mild stress].

Wild Ginseng
​”KING OF HERBS” Anti Stress & Fatigue, Promotes Strength & Endurance, AMPK activator

1. Ginsenoside Rc, an active component of Panax ginseng, stimulates glucose uptake in C2C12 myotubes through an AMPK-dependent mechanism
2. Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathway
3. Korean Red Ginseng attenuates ethanol-induced steatosis and oxidative stress via AMPK/Sirt1 activation
4. Fermented Ginseng Attenuates Hepatic Lipid Accumulation and Hyperglycemia through AMPK Activation
5. Korean red ginseng (Panax ginseng) improves insulin sensitivity and attenuates the development of diabetes in Otsuka Long-Evans Tokushima fatty rats
6. Anti-diabetic effect of black ginseng extract by augmentation of AMPK protein activity and upregulation of GLUT2 and GLUT4 expression in db/db mice
7. An enzymatically fortified ginseng extract inhibits proliferation and induces apoptosis of KATO3 human gastric cancer cells via modulation of Bax, mTOR, PKB and IκBα
8. Red ginseng extracts attenuate skin inflammation in atopic dermatitis through p70 ribosomal protein S6 kinase activation
9. Role of ginsenosides, the main active components of Panax ginseng, in inflammatory responses and diseases
10. Studies on the Anti – aging Action of Korean Ginseng
11. Effects of red ginseng extract on UVB irradiation-induced skin aging in hairless mice
12. Effects of ginseng saponins isolated from red ginseng on ultraviolet B-induced skin aging in hairless mice
13. The Preventive Effect of Ginseng with Du-Zhong Leaf of Protein Metabolism in Aging
14. Nanoemulsion comprising metabolites of ginseng saponin as an active component and a method for preparing the same, and a skin-care composition for anti-aging containing the same
15. Cancer Prevention and Therapeutics: Panax Ginseng.
16. Chemistry and Cancer Preventing Activities of Ginseng Saponinsand Some Related Triterpenoid Compounds
17. Inflammation, Cancer, and Targets of Ginseng
18. In vitro anti-cancer activity and structure–activity relationships of natural products isolated from fruits of Panax ginseng
19. Cancer chemopreventive and therapeutic activities of red ginseng
20. Ginseng and Diabetes
21. American Ginseng (Panax quinquefolius L) Reduces Postprandial Glycemia in Nondiabetic Subjects and Subjects With Type 2 Diabetes Mellitus
22. Herbal remedies in the management of diabetes: Lessons learned from the study of ginseng
23. Korean red ginseng (Panax ginseng) improves glucose and insulin regulation in well-controlled, type 2 diabetes: Results of a randomized, double-blind, placebo-controlled study of efficacy and safety
24. Effect of Crude Saponin of Korean Red Ginseng on High Fat Diet-Induced Obesity in the Rat
25. Korean red ginseng (Panax ginseng) prevents obesity by inhibiting angiogenesis in high fat diet-induced obese C57BL/6J mice
26. A ginseng metabolite, compound K, induces autophagy and apoptosis via generation of reactive oxygen species and activation of JNK in human colon cancer cells
27. Ginseng treatment attenuates autophagic cell death in chronic cyclosporine nephropathy
28. Effects of Panax ginseng extract on exercise-induced oxidative stress
29. Ginseng administration protects skeletal muscle from oxidative stress induced by acute exercise in rats
30. Effect of fermented Panax ginseng extract (GINST) on oxidative stress and antioxidant activities in major organs of aged rats

Astragalus
​”SUPER IMMUNE BOOSTER” Improves Energy, Promotes Longevity, Anti Aging, Builds Qi, Preserves Telomere Length, mTOR inhibitor

1. Astragalus polysaccharides alleviates glucose toxicity and restores glucose homeostasis in diabetic states via activation of AMPK
2. Astragalus polysaccharide induces anti-inflammatory effects dependent on AMPK activity in palmitate-treated RAW264.7 cells
3. Astragalus polysaccharide stimulates glucose uptake in L6 myotubes through AMPK activation and AS160/TBC1D4 phosphorylation
4. Astragalus Polysaccharide Improves Palmitate-Induced Insulin Resistance by Inhibiting PTP1B and NF-κB in C2C12 Myotubes
5. Astragalus polysaccharide attenuates free fatty acid-induced toxicity by activating AMPK in C2C12 myoblasts
6. Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells
7. Astragalus polysaccharides decrease muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signalling in 5/6 nephrectomised rats
8. Mitochondrial Protection and Anti-aging Activity of Astragalus Polysaccharides and Their Potential Mechanism
9. Anti-Aging Implications of Astragalus Membranaceus (Huangqi): A Well-Known Chinese Tonic
10. Deferring senile effect of polysaccharides from Angelica and Astragalus on aging mice
11. Anti-oxidative effect of total extract of astragalus(TEA) on aging mice
12. Research Astragalus and Cell on Aging
13. Astragalus-Based Chinese Herbs and Platinum-BasedChemotherapy for Advanced Non–Small-Cell Lung Cancer:Meta-Analysis of Randomized Trials
14. Extraction, characterization of Astragalus polysaccharides and its immune modulating activities in rats with gastric cancer
15. Astragalus saponins induce growth inhibition and apoptosis in human colon cancer cells and tumor xenograft
16. Astragalus polysaccharide injection integrated with vinorelbine and cisplatin for patients with advanced non-small cell lung cancer: effects on quality of life and survival
17. Traditional Chinese medicine Astragalus reverses predominance of Th2 cytokines and their up-stream transcript factors in lung cancer patients
18. Safety and pharmacokinetic trial of docetaxel plus an Astragalus-based herbal formula for non-small cell lung cancer patients
19. Astragalus extract inhibits destruction of gastric cancer cells to mesothelial cells by anti-apoptosis
20. Astragalus Polysaccharides: An Effective Treatment for Diabetes Prevention in NOD Mice
21. Astragalus polysaccharides decreased the expression of PTP1B through relieving ER stress induced activation of ATF6 in a rat model of type 2 diabetes
22. Biological Active Ingredients of Traditional Chinese Herb Astragalus membranaceus on Treatment of Diabetes: A Systematic Review
23. Astragalus Polysaccharide Suppresses Skeletal Muscle Myostatin Expression in Diabetes: Involvement of ROS-ERK and NF-κB Pathways
24. Astragalus membranaceus-Polysaccharides Ameliorates Obesity, Hepatic Steatosis, Neuroinflammation and Cognition Impairment without Affecting Amyloid Deposition in Metabolically Stressed APPswe/PS1dE9 Mice
25. Insulin Sensitization and Anti-obesity Effects of Astragalus Polysaccharide on High Fat Diet-fed C57BL/6J Mice
26. Astragalus polysaccharide improves insulin sensitivity in KKAy mice: Regulation of PKB/GLUT4 signaling in skeletal muscle
27. Hypoglycemic effect of polysaccharide enriched extract of Astragalus membranaceus in diet induced insulin resistant C57BL/6J mice and its potential mechanism
28. Drosophila melangogaster longevity test for Astragalus membranaceus
29. Astragalus polysaccharides inhibits PCV2 replication by inhibiting oxidative stress and blocking NF-κB pathway
30. Aqueous extract of Astragalus mongholicusameliorates high cholesterol diet induced oxidativeinjury in experimental rats models

Cordyceps
“HERBAL TONIC SUPERSTAR” Boosts Energy & Improves Oxygen Utilization, Increases Endurance

1. Cordycepin Down-Regulates Multiple Drug Resistant (MDR)/HIF-1α through Regulating AMPK/mTORC1 Signaling in GBC-SD Gallbladder Cancer Cells
2. Cordycepin activates AMP‐activated protein kinase (AMPK) via interaction with the γ1 subunit
3. Cordycepin Inhibits Lipopolysaccharide (LPS)-Induced Tumor Necrosis Factor (TNF)-α Production via Activating AMP-Activated Protein Kinase (AMPK) Signaling
4. Cordyceps cicadae mycelia and its active compound HEA exert beneficial effects on blood glucose in type 2 diabetic db/db mice
5. Antiproliferative and Apoptosis-Inducing Activities of 4-Isopropyl-2,6-bis(1-phenylethyl)phenol Isolated from Butanol Fraction of Cordyceps bassiana
6. Polysaccharides from the Medicinal Mushroom Cordyceps taii Show Antioxidant and Immunoenhancing Activities in a D-Galactose-Induced Aging Mouse Model
7. Protective Effects on Mitochondria and Anti-Aging Activity of Polysaccharides from Cultivated Fruiting Bodies of Cordyceps militaris
8. [An experimental study on anti-aging action of Cordyceps extract].
9. THE PURIFICATION AND ANTIOXIDATIVE ACTIVITIES IN D‐GALACTOSE‐INDUCED AGING MICE OF A WATER‐SOLUBLE POLYSACCHARIDE FROM CORDYCEPS GUNNII (BERK.) BERK. MYCELIUM
10. Ecology‐based screen identifies new metabolites from a Cordyceps‐colonizing fungus as cancer cell proliferation inhibitors and apoptosis inducers
11. Induction of apoptosis by aqueous extract of Cordyceps militaris through activation of caspases and inactivation of Akt in human breast cancer MDA-MB-231 Cells.
12. Polysaccharide of Cordyceps sinensis Enhances Cisplatin Cytotoxicity in Non–Small Cell Lung Cancer H157 Cell Line
13. Antitumor activity of Cordyceps militaris on human cancer cell line
14. [Inhibitory effects of cordyceps extract on growth of colon cancer cells].
15. Anti-cancer Effects of CME-1, a Novel Polysaccharide, Purified from the Mycelia of Cordyceps sinensis against B16-F10 Melanoma Cells
16. A Contemporary Treatment Approach to Both Diabetes and Depression by Cordyceps sinensis, Rich in Vanadium
17. Anti-hyperglycemic Activity of Natural and Fermented Cordyceps sinensis in Rats with Diabetes Induced by Nicotinamide and Streptozotocin
18. Immunoregulatory Cordyceps sinensis increases regulatory T cells to Th17 cell ratio and delays diabetes in NOD mice
19. Effects of Extract from Solid-State Fermented Cordyceps sinensis on Type 2 Diabetes Mellitus
20. Effect of Cordyceps militaris extract and active constituents on metabolic parameters of obesity induced by high-fat diet in C58BL/6J mice
21. Effects of North Cordyceps sinensis’s Extract on the Reproductivity and Longevity of the Drosophila melangogaster
22. Anti-inflammation Effects of Cordyceps sinensis Mycelium in Focal Cerebral Ischemic Injury Rats
23. Effects of the Immunomodulatory Agent Cordyceps militaris on Airway Inflammation in a Mouse Asthma Model
24. Anti-inflammation and antioxidant effect of Cordymin, a peptide purified from the medicinal mushroom Cordyceps sinensis, in middle cerebral artery occlusion-induced focal cerebral ischemia in rats
25. A potent sphingomyelinase inhibitor from Cordyceps mycelia contributes its cytoprotective effect against oxidative stress in macrophages
26. Protective effect of Cordyceps militaris against high glucose-induced oxidative stress in human umbilical vein endothelial cells
27. Cordyceps militaris Extract Protects Human Dermal Fibroblasts against Oxidative Stress-Induced Apoptosis and Premature Senescence
28. Vanadium-Enriched Cordyceps sinensis, a Contemporary Treatment Approach to Both Diabetes and Depression in Rats
29. Increasing oxidative stress tolerance and subculturing stability of Cordyceps militaris by overexpression of a glutathione peroxidase gene
30. Effect of polysaccharide from cultured Cordyceps sinensis on immune function and anti-oxidation activity of mice exposed to 60Co

Schizandra
​”THE HERB THAT DOES IT ALL” Boosts Memory & Alertness, Supports All Organs & Bodily Functions, Relieves Fatigue

1. Huang-Lian-Jie-Du-Tang Supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce Improved Glucose Tolerance by Potentiating Insulinotropic Actions in Islets in 90% Pancreatectomized Diabetic Rats
2. Schisandra chinensis berry extract protects against steatosis by inhibiting histone acetylation in oleic acid–treated HepG2 cells and in the livers of diet-induced obese mice
3. Protective effect of acidic polysaccharide from Schisandra chinensis on acute ethanol-induced liver injury through reducing CYP2E1-dependent oxidative stress
4. Anticancer activity of gomisin J from Schisandra chinensis fruit
5. SCP, a polysaccharide from Schisandra chinensis, induces apoptosis in human renal cell carcinoma Caki-1 cells through mitochondrial-dependent pathway via inhibition of ERK activation
6. Schisandra chinensis produces the antidepressant-like effects in repeated corticosterone-induced mice via the BDNF/TrkB/CREB signaling pathway
7. Antidepressant-like effects and cognitive enhancement of Schisandra chinensis in chronic unpredictable mild stress mice and its related mechanism
8. Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells
9. Antioxidative and Cardioprotective Effects of Schisandra chinensis Bee Pollen Extract on Isoprenaline-Induced Myocardial Infarction in Rats
10. Lignans from Schisandra chinensis ameliorate cognition deficits and attenuate brain oxidative damage induced by D-galactose in rats
11. In Vivo Antioxidant Action of a Lignan-Enriched Extract of Schisandra Fruit and an Anthraquinone-Containing Extract of Polygonum Root in Comparison with Schisandrin B and Emodin
12. Metabolomics study of the therapeutic mechanism of Schisandra chinensis lignans on aging rats induced by d-galactose
13. Kudsuphilactone B, a nortriterpenoid isolated from Schisandra chinensis fruit, induces caspase-dependent apoptosis in human ovarian cancer A2780 cells
14. Constituents of Schisandra verruculosa. and Their Cytotoxic Effect on Human Cancer Cell Lines
15. Gomisin N isolated from Schisandra chinensis significantly induces anti-proliferative and pro-apoptotic effects in hepatic carcinoma
16. Antioxidant and anti-proliferative activities of five compounds from Schisandra chinensis fruit
17. Isolation of lignans from Schisandra chinensis with anti-proliferative activity in human colorectal carcinoma: Structure–activity relationships
18. Antitumor and immunomodulatory activity of a water-soluble low molecular weight polysaccharide from Schisandra chinensis (Turcz.) Baill
19. Antitumor and antiangiogenic activity of Schisandra chinensis polysaccharide in a renal cell carcinoma model
20. Schisandra chinensis fruit extract attenuates albuminuria and protects podocyte integrity in a mouse model of streptozotocin-induced diabetic nephropathy
21. Anti-diabetic effects of polysaccharides from ethanol-insoluble residue of Schisandra chinensis (Turcz.) Baill on alloxan-induced diabetic mice
22. In Vitro Antioxidant activities and anti-diabetic effect of a polysaccharide from Schisandra sphenanthera in rats with type 2 diabetes
23. Huang-Lian-Jie-Du-Tang Supplemented with Schisandra chinensis Baill. and Polygonatum odoratum Druce Improved Glucose Tolerance by Potentiating Insulinotropic Actions in Islets in 90% Pancreatectomized Diabetic Rats
24. Schisandra Extracts on Blood Glucose of Diabetic Mice
25. Schisandra chinensis fruit modulates the gut microbiota composition in association with metabolic markers in obese women: a randomized, double-blind placebo-controlled study
26. Anti-obesity effect of Schisandra chinensis in 3T3-L1 cells and high fat diet-induced obese rats
27. Schisandra chinensis berry extract protects against steatosis by inhibiting histone acetylation in oleic acid–treated HepG2 cells and in the livers of diet-induced obese mice
28. Schisandra chinensis Prevents Hepatic Lipid Peroxidation and Oxidative Stress in Rats Subjected to Heat Environmental Stress
29. Ameliorative Effects of 5-Hydroxymethyl-2-furfural (5-HMF) from Schisandra chinensis on Alcoholic Liver Oxidative Injury in Mice
30. Schisandra Lignan Extract Protects against Carbon Tetrachloride-Induced Liver Injury in Mice by Inhibiting Oxidative Stress and Regulating the NF-κB and JNK Signaling Pathways

Polyrhachis Ant
“HERB OF KINGS” Dramatic Increase in Strength & Power, Speeds Workout Recovery

1. Analgesic and Anti-inflammatory Activities of Total Extract and Individual Fractions of Chinese Medicinal Ants Polyrhachis lamellidens
2. Nutritional composition of Polyrhachis vicina Roger(Edible Chinese black ant)
3. Constituents from the edible Chinese black ants (Polyrhachis dives) showing protective effect on rat mesangial cells and anti-inflammatory activity
4. Dopamine derivatives from the insect Polyrhachis dives as inhibitors of ROCK1/2 and stimulators of neural stem cell proliferation

Red Asparagus Root
“THE FLYING HERB” Elevates Mood, Promotes Deep Sleep, Lung Tonic – Increases the Lung’s Ability to Extract Qi (life force) from Air

1. Enzyme-treated Asparagus officinalis Extract Shows Neuroprotective Effects and Attenuates Cognitive Impairment in Senescence-accelerated Mice
2. In vitro antioxidant and antitumor activities of polysaccharides extracted from Asparagus officinalis
3. Asparagus officinalis extract controls blood glucose by improving insulin secretion and β-cell function in streptozotocin-induced type 2 diabetic rats
4. T-DNA organization in tumor cultures and transgenic plants of the monocotyledon Asparagus officinalis
5. Evaluation of drying technologies for retention of physical quality and antioxidants in asparagus (Asparagus officinalis, L.)
6. The aqueous extract of Asparagus officinalis L. by‐product exerts hypoglycaemic activity in streptozotocin‐induced diabetic rats
7. Hypolipidaemic and hepatoprotective effects of ethanolic and aqueous extracts from Asparagus officinalis L. by‐products in mice fed a high‐fat diet
8. Asparagus adscendens (Shweta musali) stimulates insulin secretion, insulin action and inhibits starch digestion
9. Insulin secretory actions of extracts of Asparagus racemosus root in perfused pancreas, isolated islets and clonal pancreatic β-cells
10. Antihyperglycaemic activity of Asparagus racemosus roots is partly mediated by inhibition of carbohydrate digestion and absorption, and enhancement of cellular insulin action
11. Enzyme-treated Asparagus Extract (ETAS) Enhances Memory in Normal Rats and Induces Neurite-outgrowth in PC12 Cells
12. Effects of Temperature on Longevity, Reproduction, and Development of the Asparagus Aphid (Homoptera: Aphididae) and the Parasitoid, Diaeretiella rapae (Hymenoptera: Braconidae)
13. Therapeutic effect of ethyl acetate extract from Asparagus cochinchinensis on phthalic anhydride-induced skin inflammation
14. Anti-nociceptive and anti-inflammatory effects of methanolic extract of Asparagus pubescens root in rodents
15. Saponin-enriched extract of Asparagus cochinchinensis alleviates airway inflammation and remodeling in ovalbumin-induced asthma model
16. Effect of Asparagus‐P® on cell metabolism of cultured kidney and inflammation‐mediating cells
17. Neuroprotective Activity of Asparagus racemosus Linn. Against Ethanol-Induced Cognitive Impairment and Oxidative Stress in Rats Brain: Auspicious for Controlling the Risk of Alzheimer’s Disease
18. Protective effects of Asparagusracemosus on oxidative damage in isoniazid-induced hepatotoxic rats: an in vivo study
19. Hypoglycemic, antioxidant and hypolipidemic activity of Asparagus racemosus on streptozotocin-induced diabetic in rats
20. Action of Asparagus racemosus Against Streptozotocin-Induced Oxidative Stress
21. Hypolipidemic and antioxidant activities of Asparagus racemosus in hypercholesteremic rats
22. Effect of methanolic extract of Asparagus racemosus Willd. on lipopolysaccharide induced-oxidative stress in rats
23. LC–ESI–MS/MS analysis of Asparagus racemosus Willd. roots and its protective effects against t-BHP induced oxidative stress in rats
24. Effect of Asparagus racemosus on sexual dysfunction in hyperglycemic male rats
25. Enzyme‐Treated Asparagus Extract Promotes Expression of Heat Shock Protein and Exerts Antistress Effects
26. Cytosolic acidification and γ-aminobutyric acid synthesis during the oxidative burst in isolated Asparagus sprengeri mesophyll cells
27. Ameliorative effect of Asparagus racemosus root extract against pentylenetetrazol-induced kindling and associated depression and memory deficit
28. Evaluation of Anxiolytic-Like Effect of Aqueous Extract of Asparagus Stem in Mice
29. Anti-neuroinflammatory constituents from Asparagus cochinchinensis
30. The New Phytoformula Containing Morus alba, Schizandra sinensis and Asparagus cochinchinensis Inhibits Lung Inflammation in vitro and in vivo

Tribulus
Enhances Mood, Protects Urinary Tract, Increases Sperm Count, Restores Vigor, Vitality & Stamina

1. Antioxidant Activities and Anti-tyrosinase Activity of Tribulus terrestris
2. Pilot Study on the Effect of Botanical Medicine (Tribulus terrestris) on Serum Testosterone Level and Erectile Function in Aging Males With Partial Androgen Deficiency (PADAM)
3. Evaluating the efficacy in improving male sexual function with a new natural compound made of Tribulus Terrestris, Biovis and Alga Ecklonia Cava and its synergic anti-aging action
4. Hypoglycemic Effect of Saponin from Tribulus terrestris
5. [The inhibitory effect of saponins from Tribulus terrestris on Bcap-37 breast cancer cell line in vitro].
6. Aqueous extract of Tribulus terrestris Linn induces cell growth arrest and apoptosis by down-regulating NF-κB signaling in liver cancer cells
7. Saponins from Tribulus terrestris L. Are Less Toxic for Normal Human Fibroblasts than for Many Cancer Lines: Influence on Apoptosis and Proliferation
8. Terrestrosin D, a Steroidal Saponin from Tribulus terrestris L., Inhibits Growth and Angiogenesis of Human Prostate Cancer in vitro and in vivo
9. Chemopreventive potential of Tribulus terrestris against 7,12- dimethylbenz (a) anthracene induced skin papillomagenesis in mice.
10. [Investigation on inhibitory and apoptosis-inducing effects of saponins from Tribulus terrestris on hepatoma cell line BEL-7402].
11. Cytotoxic and antitumor effects of Tribulus terrestrisL fruit methanolic extract
12. Changes in gene expression of CXCR4, CCR7 and BCL2 after treatment of breast cancer cells with saponin extract from Tribulus terrestris
13. In-Silico Molecular Docking Analysis of Cancer Biomarkers with Bioactive Compounds of Tribulus terrestris
14. The Protective Effect of Tribulus terrestris in Diabetes
15. Efficacy of Tribulus Terrestris Extract on the Serum Glucose and Lipids of Women with Diabetes Mellitus
16. Hypoglycemic and hypolipidemic effects of alcoholic extract of Tribulus alatus in streptozotocin-induced diabetic rats: A comparative study with T. terrestris (Caltrop)
17. Efficacy of the Hydroalcoholic Extract of Tribulus terrestris on the Serum Glucose and Lipid Profile of Women With Diabetes Mellitus: A Double-Blind Randomized Placebo-Controlled Clinical Trial
18. ANTIHYPERLIPIDEMIC POTENTIAL OF FRUITS OF TRIBULUS TERRESTRIS LINN
19. Protective effect of an aphrodisiac herb Tribulus terrestris Linn on cadmium-induced testicular damage
20. Anti-hyperglycaemic Activity of Tribulus terrestris L Aerial Part Extract in Glucose-loaded Normal Rabbits
21. Proteomic analysis reveals the renoprotective effect of Tribulus terrestris against obesity-related glomerulopathy in rats
22. ATILIPIDEMIC ACTIVITY OF CISSUSQUADRAGULARIS AD TRIBULUS TERRESTRIS O OBESITY I HIGH FAT FED RATS
23. EFFECTS OF SAPONINS FROM TRIBULUS TERRESTRIS L. ON INSULIN RESISTANCE AND HYPERLIPIDEMIA IN THE DIET-INDUCED OBESE RATS
24. ANTI-INFLAMMATORY AND ANTIMICROBIAL ACTIVITIES OF METHANOLIC EXTRACT OF TRIBULUS TERRESTRIS LINN PLANT
25. Anti-inflammatory activity of Tribulus terrestris in RAW264.7 Cells (54.2)
26. N‑trans‑ρ‑caffeoyl tyramine isolated from Tribulus terrestris exerts anti‑inflammatory effects in lipopolysaccharide‑stimulated RAW 264.7 cells