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  • Gavin McGowen
January 10, 2020

JNK PREVENTS PREMATURE SENESCENCE

Prevention of premature senescence requires JNK activation. Premature senescence is considered as a cellular defense mechanism to prevent tumorigenesis. Although recent evidences show that c-Jun N-terminal […]
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January 10, 2020

MDM2

MDM2 antagonists attenuate the senescence-associated secretory phenotype Processes that have been linked to aging and cancer include an inflammatory milieu driven by senescent cells. Senescent cells […]
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January 14, 2020

SENESCENT CELLS, SASP & SENOLYTICS

Senescent cells are like retired workers in our bodies. They’ve stopped dividing due to stress or damage, which prevents uncontrolled growth and potential cancer. However, these […]
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January 14, 2020

Andrographis Paniculata

Andrographis Paniculata Hepatoprotective activity of Andrographolide from Andrographis paniculata against carbontetrachloride. Andrographolide protects rat hepatocytes against paracetamol-induced damage In vitro and in vivo anti-inflammatory effects of […]
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January 15, 2020

Acorus Gramineu

Alkaloids from Acorus gramineus rhizomes and their biological activity Alpha-asarone, a major component of Acorus gramineus, attenuates corticosterone-induced anxiety-like behaviours via modulating TrkB signaling process Anti-Candida […]
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January 15, 2020

Carnosine

Carnosine Carnosine, the protective, anti-aging peptide The roles of carnosine in aging of skeletal muscle and in neuromuscular diseases Would carnosine or a carnivorous diet help […]
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January 15, 2020

Celastrol

  Celastrol (God Vine) 532 Priming of Stem Cells With celastrol to Enhance Survival for Cell Therapy A lipidomics investigation into the intervention of celastrol in […]
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January 15, 2020

Curcumin

  Curcumin Curcumin ameliorates arterial dysfunction and oxidative stress with aging Curcumin and aging Curcumin Extends Life Span, Improves Health Span, and Modulates the Expression of […]
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January 15, 2020

EF24 (Tumeric Root)

  EF24 (Tumeric Root) A liposomal formulation of the synthetic curcumin analog EF24 (Lipo-EF24) inhibits pancreatic cancer progression: towards future combination therapies Abstract P4-16-02: EF24 targets […]
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