January 7, 2020
JAK inhibition alleviates the cellular senescence-associated secretory phenotype and frailty in old age A hallmark of aging is chronic sterile inflammation, which is closely associated with […]
January 8, 2020
Oncogene activation plays a critical role in human health and aging, but it’s a double-edged sword. Oncogenes are genes that, when activated, promote uncontrolled cell growth […]
January 10, 2020
Prevention of premature senescence requires JNK activation. Premature senescence is considered as a cellular defense mechanism to prevent tumorigenesis. Although recent evidences show that c-Jun N-terminal […]
January 10, 2020
MDM2 antagonists attenuate the senescence-associated secretory phenotype Processes that have been linked to aging and cancer include an inflammatory milieu driven by senescent cells. Senescent cells […]
January 14, 2020
Senescent cells are like retired workers in our bodies. They’ve stopped dividing due to stress or damage, which prevents uncontrolled growth and potential cancer. However, these […]
January 14, 2020
Andrographis Paniculata Hepatoprotective activity of Andrographolide from Andrographis paniculata against carbontetrachloride. Andrographolide protects rat hepatocytes against paracetamol-induced damage In vitro and in vivo anti-inflammatory effects of […]
January 15, 2020
Alkaloids from Acorus gramineus rhizomes and their biological activity Alpha-asarone, a major component of Acorus gramineus, attenuates corticosterone-induced anxiety-like behaviours via modulating TrkB signaling process Anti-Candida […]
January 15, 2020
Carnosine Carnosine, the protective, anti-aging peptide The roles of carnosine in aging of skeletal muscle and in neuromuscular diseases Would carnosine or a carnivorous diet help […]
January 15, 2020
Celastrol (God Vine) 532 Priming of Stem Cells With celastrol to Enhance Survival for Cell Therapy A lipidomics investigation into the intervention of celastrol in […]